Reliably unreliable nanotechnologies

Lead Research Organisation: University of Southampton
Department Name: Sch of Electronics and Computer Sci

Abstract

Nanoscale resistive switching (RS) elements, also known as memristors, are nowadays regarded as a promising solution for establishing next-generation memory, due to their infinitesimal dimensions, their capacity to store multiple bits of information per element and the miniscule energy required to write distinct states. Currently, the microelectronics community aspires exploiting these attributes in a deterministic fashion where information encoding and processing is realised via static representations. In consequence, research efforts are focused on optimising memristor technology in a "More Moore" approach to comply with existing CMOS devices attributes, i.e. high-yield, supreme reproducibility, very long retention characteristics and conventional circuit design formalisms. The functional properties of such elements are however associated with irreversible rate-limiting electro/thermo-dynamic changes that often bring them in "far from equilibrium" conditions, manifesting opportunities for unconventional computing within a probabilistic framework.

This fellowship aims exploiting the strong emergence of ultra-thin functional oxides, nanoscale resistive switching elements and large-scale systems of the same. We will first investigate the effect of quantum phase transitions and the mechanisms leading into thermodynamically stable/unstable long-range order/disorder of distinct materials. These mechanisms will then be exploited in nanoscale solid-state devices for establishing the state-of-the-art in non-volatile multi-state memory but also volatile elements that could potentially be employed as dynamic computational elements. The rich-dynamics of the later will be compared against reaction-diffusion mechanisms of naturally occurring nano-systems to facilitate novel design paradigms and emerging ICT applications for substantiating unconventional computation formalisms. A successful outcome will demonstrate a mature memristive device manufacturing technology that will be supported by the necessary design tools, for taking CMOS technology far beyond its current state-of-art.

Planned Impact

The interdisciplinary work proposed within this unconventional fellowship framework seeks providing authoritative answers to an extremely diverse audience, including: computer science, electronics, physics, materials, chemistry, neuroscience, education and other communities that are intrigued by the way memory and computation are transcribed in nanosystems. Thus the anticipated impact expands across three main areas: (1) Economy, (2) Host Institutions (Imperial College London, STFC) and UK science-base, and (3) Society.

Economy: The main beneficiaries stand to be the semiconductor and micro/nano-electronics industries. The proposed research will disentangle the fundamental processes involved in the functioning of the memristor to promote its use as a fully dynamic computation element. This newly discovered device has already impacted the memory industry, with multi-billion global businesses such as HP, Samsung, Hynix and IBM investing substantially for harnessing this technology in emerging data-storage concepts. The impact of this fellowship will thus be reflected in the semiconductor industry of tomorrow, by adjusting processing techniques and materials to accommodate the reliable fabrication of memristors as static-loads in the short-term and as purely dynamic rate-limiting computation elements in the long-term. Respective technological advancements will also be realized for employing such elements along with conventional devices in standard technologies, with the provision of extending this towards a totally probabilistic platform, supported by appropriate models and circuitry. This strategy bares significant impact for the computer-science industry as we foresee the reshaping of existing computation strategies, with the potential to facilitate novel applications that in turn could provoke further R&D investments for exploiting this technology in emerging products and services.

Host Organisations and UK-science: By combining the multi-disciplinary strengths of our collaborators and the host departments we aim to:
- Innovate using the ingredients from different disciplines for enhancing the knowledge economy.
- Develop end-to-end infrastructure from a range of technologies, design methodologies and applications.
- Cultivate inter-disciplinary IP for accelerating the commercialization of this disruptive technology.
- Foster the training of highly skilled researchers.

Society: Biology makes excellent use of resources to solve a given task, being efficient, robust, adaptable, real-time, effective, scalable and reliable. For the above reasons, any engineer would do extremely well in learning from nature. The technology we propose developing could shine more light in the way memory and computation is transcribed in biological systems. This question has often been addressed by a broad range of disciplines, from philosophy to medicine and more recently engineering. Apart from providing knowledge to society, we believe that this project could be further exploited, leading into advances on international developments, primarily in healthcare and automation, as computation-demanding spatial problems are often encountered in both application domains. Without doubt, a successful knowledge translation of this technology could significantly enhance the "quality of life" through innovating new services, improving the effectiveness of existing ones but also contributing towards sustaining environmental resources.
 
Description We have developed novel nanoscale devices (memristors) and models, as well as circuits that exploit these elements into new applications. Particularly, we have shown for the first time how such devices can be used to mimic neuronal circuits. We have also demonstrated novel insists on the fundamentals of switching mechanism via challenging Synchrotron experiments. Our developments leverage the team's interdisciplinary expertise and span across: new materials and processes, methods for characterising fundamental physical mechanisms, minuscule (close to atomic scale) devices and circuits for characterising these challenging devices. We have also demonstrated new technologies that leverage memristors unconventional dynamics for enabling real-time processing of biosignals, bringing the society a step closer to advanced machine/human interfaces and bioelectronic medicines.
Exploitation Route The focus on process development and materials is in compliance with commercially available technologies for ensuring a prompt uptake of the technology.
Our devices are currently exploited via our instrumentation boards in collaboration with UK (Sheffield and Imperial) but also international (NUDT, ETH, TU-Graz and Michigan) groups into new applications, to name a few: RRAM, neuromorphic, analogue and RF circuits. Moreover, through our company ArC Instruments, industrial and academic customers have acquired our premier ArC One en-masse characterisation board for accelerating process development and application demonstrators.
Sectors Aerospace, Defence and Marine,Digital/Communication/Information Technologies (including Software),Education,Electronics,Environment,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology

URL http://www.nanomemristors.com
 
Description The unconventional dynamics of our prototypes are currently exploited for facilitating neuromorphic architectures that are typically used in extracting and classifying patterns. We have also demonstrated a disruptive approach where memristive devices are used for processing efficiently biosignals in real time; this brings new prospects to advanced neural interfaces and the field of bioelectronics. We have also pioneered state-of-art tools (ArC One en-masse characterisation board) and models (Verilog-A memristor model) for acceleration the pace of discovery both within academic and industry. These tools are now available from our spin-out company ArC Instruments and we already have numerous customers (ArC One) as well as users.
First Year Of Impact 2014
Sector Aerospace, Defence and Marine,Digital/Communication/Information Technologies (including Software),Education,Electronics,Manufacturing, including Industrial Biotechology
Impact Types Economic

 
Description International Technology Roadmap for Semiconductors
Geographic Reach Multiple continents/international 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Dr Prodromakis is a member of the Emerging Research Devices working group that shapes the International Technology Roadmap for Semiconductors (ITRS). The objective of the ITRS is to ensure cost-effective advancements in the performance of the integrated circuit and the advanced products and applications that employ such devices, thereby continuing the health and success of this industry.
URL http://www.itrs.net/home.html
 
Description Future and Emerging Technologies
Amount € 2,100,000 (EUR)
Funding ID 612058 
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start 11/2013 
End 05/2017
 
Description Impact Acceleration Account
Amount £150,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 01/2018 
End 01/2019
 
Description Lloyds Register Foundation International Consortium in Nanotechnologies
Amount £3,000,000 (GBP)
Organisation Lloyd's Register Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2015 
End 04/2022
 
Description PhD Scholarships
Amount £75,000 (GBP)
Organisation AG Leventis Foundation 
Sector Charity/Non Profit
Country Cyprus
Start 07/2011 
End 06/2014
 
Description Royal Academy of Engineering Chair in Emerging technologies
Amount £2,800,000 (GBP)
Organisation Royal Academy of Engineering 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2019 
End 12/2029
 
Description Royal Society Industry Fellowship
Amount £281,550 (GBP)
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2017 
End 08/2021
 
Description SYNCH
Amount € 4,000,000 (EUR)
Organisation EU-T0 
Sector Public
Country European Union (EU)
Start 01/2019 
End 01/2023
 
Description UKRI Centre for Doctoral Training in Machine Intelligence for Nano-electronic Devices and Systems
Amount £5,820,891 (GBP)
Funding ID EP/S024298/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 03/2019 
End 09/2027
 
Title Memristor Verilog-A model 
Description The translation of emerging application concepts that exploit Resistive Random Access Memory (ReRAM) into large-scale practical systems requires realistic, yet computationally efficient, empirical models that can capture all observed physical devices. Here, we present a Verilog-A ReRAM model built upon experimental routines performed on TiOx-based prototypes. This model was based on custom biasing protocols, specifically designed to reveal device switching rate dependencies on a) bias voltage and b) initial resistive state. Our model is based on the assumption that a stationary switching rate surface m(R,v) exists for sufficiently low voltage stimulation. The proposed model comes in compact form as it is expressed by a simple voltage dependent exponential function multiplied with a voltage and initial resistive state dependent second order polynomial expression, which makes it suitable for fast and/or large-scale simulations. 
Type Of Material Improvements to research infrastructure 
Year Produced 2017 
Provided To Others? Yes  
Impact Enabled the circuits and systems community to innovate novel circuitry and systems. 
URL https://arxiv.org/abs/1703.01167
 
Title RRAM instrumentation 
Description Selector-less crossbar arrays of resistive random access memory (RRAM), also known as memristors, conduct large sneak currents during operation which can significantly corrupt the accuracy of cross-point analogue resistance measurements. In order to mitigate this issue we have designed, built and tested a customised instrument that forces redistribution of sneak currents within the crossbar array and thus dramatically increases the measurement accuracy. 
Type Of Material Improvements to research infrastructure 
Year Produced 2014 
Provided To Others? Yes  
Impact Our instrument facilitates the full exploitation of RRAM scaling (beyond Moore) benefits without reoccurring to additional fabrication steps for monolithically integrating selector devices. At the same time, it provides a versatile and powerful tool for RRAM process development as it could facilitate large-scale testing in an automated manner; speeding up the discovery and classification of new materials in RRAM. This has more recently led to starting-up ArC Instruments Ltd, a company that delivers high performance testing platforms for characterising 'en masse' novel technologies in a fast and automated fashion. The company has been profitable from its first year without relying on any external funding. Customers include Toshiba as well as other international leading research and industrial groups. 
URL http://www.arc-instruments.co.uk
 
Title Activity dependent model 
Description We have developed a novel SPICE model that captures activity dependent resistive switching of solid-state memristive devices. The model is demonstrated via a number of simulation cases and is benchmarked against measured results acquired by solid-state TiO2 ReRAM. 
Type Of Material Computer model/algorithm 
Year Produced 2015 
Provided To Others? Yes  
Impact Simulation of biophysically realistic neuromorphic systems. 
URL http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120506
 
Title Memristor Verilog-A model 
Description The translation of emerging application concepts that exploit Resistive Random Access Memory (ReRAM) into large-scale practical systems requires realistic, yet computationally efficient, empirical models that can capture all observed physical devices. Here, we present a Verilog-A ReRAM model built upon experimental routines performed on TiOx-based prototypes. This model was based on custom biasing protocols, specifically designed to reveal device switching rate dependencies on a) bias voltage and b) initial resistive state. Our model is based on the assumption that a stationary switching rate surface m(R,v) exists for sufficiently low voltage stimulation. The proposed model comes in compact form as it is expressed by a simple voltage dependent exponential function multiplied with a voltage and initial resistive state dependent second order polynomial expression, which makes it suitable for fast and/or large-scale simulations. 
Type Of Material Computer model/algorithm 
Year Produced 2017 
Provided To Others? Yes  
Impact Enabled the circuits and systems community to innovate novel circuitry and systems. 
URL https://arxiv.org/abs/1703.01167
 
Title Volatile memristor model 
Description We have developed a new memristor SPICE model that introduces volatile effects, which can render a rate-dependent bipolar nonvolatile switching operation. The model is demonstrated via a number of simulation cases and is benchmarked against measured results acquired by solid-state TiO2 ReRAM. 
Type Of Material Computer model/algorithm 
Year Produced 2014 
Provided To Others? Yes  
Impact Currently, no available SPICE memristor model accounts for both nonvolatile and volatile resistive switching characteristics, the coexistence of which has been recently demonstrated to manifest on practical ReRAM. Besides exploiting this model for studying RRAM retention, our model can for the first time facilitate a more biorealistic exploitation of RRAM cells as chemical synapse emulators; allowing to capture both short- and long-term dynamics that co-exist in real neural circuits. This opens up a new design paradigm for neuromorphic engineering. 
URL http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6680642
 
Description GlaxoSmithKline 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution Shaping the Bioelectronics agenda. Attended the inaugural Bioelectronics Summit in New York, December 2013. Also our team has directly contributed towards addressing grand challenges of state-of-art neural interfaces related with power consumption and bandwidth requirements that prohibit upscaling above 1,000 channels.
Collaborator Contribution Provided access to data and facilities for in-vitro/-vivo testing at Stevenage.
Impact Lead into the award of a Royal Society Industry Fellowship for translating technology developed through EPSRC funding into Bioelectronic products. Lead to the establishment of neuroLink ltd, a start-up that promotes the use of emerging resistive memory technology (memristors) as efficient computation (on-node processing) elements.
Start Year 2013
 
Description NUDT 
Organisation National University of Defense Technology
Country China 
Sector Academic/University 
PI Contribution Provided experience and expertise in memristive devices.
Collaborator Contribution Provided a full time PhD student.
Impact Through this collaboration we have proved that solid-state memristive devices also possess memcapacitive attributes that provide new opportunities in exploiting this technology in RF and Microwave systems.
Start Year 2012
 
Title Method and system for detecting events in an input signal 
Description An efficient method for detecting spiking events in real-time with memristor technology. This method has shown potential for significant improvements in power consumption (2-3 orders of magnitude from current state-of-art) and bandwidth (x200 improvement). 
IP Reference N409296GB 
Protection Patent application published
Year Protection Granted 2016
Licensed No
Impact This patent application is part of the IP portfolio of our new start-up neuroLink ltd.
 
Title Method and system for detecting events in an input signal 
Description This invention leverages memristors intrinsic thresholding capability for detecting neuronal spiking activity. 
IP Reference N409296GB 
Protection Patent application published
Year Protection Granted 2017
Licensed Commercial In Confidence
Impact Prof Prodromakis was awarded a prestigious Royal Society Industry Fellowship that exploits this technology in developing bioelectronic devices for Galvani Bioelectronics.
 
Title Method and system for processing data from a sensor 
Description An efficient method for classifying spiking events in real-time with memristor technology. This method has shown potential for significant improvements in power consumption (2-3 orders of magnitude from current state-of-art) and bandwidth (x200 improvement). 
IP Reference N409294GB 
Protection Patent application published
Year Protection Granted 2016
Licensed No
Impact This patent application is part of the IP portfolio of our new start-up neuroLink ltd.
 
Title Tunable CMOS Circuit, template matching module, neural spike recording system, and fuzzy logic gate 
Description The present invention relates to a tunable CMOS circuit, a template matching module for determining a match between an analogue neural spike signal and a programmable template, a neural spike recording system for recording neuronal activity in-vivo, and a fuzzy logic gate. 
IP Reference GB17508512.7 
Protection Patent application published
Year Protection Granted 2017
Licensed No
Impact The background science underpinning this invention is currently considered for publication in Nature Communications. Also recently (Jan 2018), we have secured funding from the University of Southampton for developing a proof of concept platform for demonstrating to potential investors/customers.
 
Company Name ARC Instruments 
Description ArC Instruments delivers high performance testing platforms for characterising 'en masse' novel technologies in a fast and automated fashion. The company was born out of the necessity to efficiently close the loop between characterisation and development of emerging memory technologies, like Resistive Random Access Memory (RRAM). We have taken a user-centric approach in addressing this niche by developing high-precision testing instruments and intuitive software that are easy to operate. Our instruments are ideal for implementing a variety of read and write protocols along with developing advanced automated test modules for nearly all technologies in the emerging non-volatile memory sector. And besides characterization purposes, our products can effortlessly enable the hybrid interfacing among distinct technologies, for example CMOS circuitry and RRAM, for demonstrating concepts and applications. 
Year Established 2015 
Impact Our instruments offer two major benefits to users: •A software system designed specifically to allow easy development of advanced bespoke testing protocols. •A versatile hardware infrastructure that can handle a variety of testing requirements in voltage, current and time resolutions. These benefits are essential for achieving real-time access to test samples, both on-wafer and in-package, for ensuring targeted, prompt and overall cost-effective technological developments.
Website http://www.arc-instruments.co.uk/
 
Company Name neuroLink Ltd. 
Description NeuroLink Ltd is responsible for developing efficient on-node hardware processors for neural interfacing technologies. 
Year Established 2016 
Impact - Submitted 2 patent applications with one more under filing. - Showcased technology in Nature Communications.
 
Description 1st Annual ICON conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact The conference provided an opportunity for the ICON network to come together to consider the grand challenges in nanotechnology. The agenda of this meeting is attached:
- Welcome - the ICON vision, Themis Prodromakis - ICON Project Director
- Promoting safety - the Foundation vision, Jan Pryzdatek -Associate Director of Programmes, Lloyd's Register Foundation
- Nanotechnology 'in the wild' - the Industry vision, Ivy Fang - LR Group representative
- Safety of novel nano materials, Steve Hankin - IMO
- Nanotechnology - research to impact. Vladimir Falko - Research Director of National Graphene Institute
- Applications of nanotechnology in the oil and gas industry, Norani Mohammed - Application of Nano materials
- Internet of Things, Jamie Phillips - Nano devices
- Where can Nano take you?, Laura Vivar (NSIRC PhD student)
- Rebecca Boston (RA Fellowship supported by the Foundation)
- Nanotechnology - grand challenges and its impact, Giacomo Prando, Editor of Nature Nano
- ICON Student Overview
Year(s) Of Engagement Activity 2017
URL http://www.lrf-icon.com/events/workshops/first-icon-conference
 
Description CAS-FEST 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Type Of Presentation workshop facilitator
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact World-leased experts in the field were available for taking questions and facilitating a brain-storming session. This was particularly useful for young engineers (PhDs, MSc students) who had the chance to talk to distinguished scientists (both from academia and industry) not just for research but also future directions (skills, employment, etc).

This workshop facilitated additional links among international groups that allowed people to find jobs, exchange knowledge and form new collaborations (joint publications and grants).
Year(s) Of Engagement Activity 2014
URL http://iscas2014.org/cas-fest
 
Description International Conference on Memristive Materials, Devices & Systems (MEMRISYS 2017) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact MEMRISYS 2017 provided a timely discussion on Memristor Technologies presenting the latest developments across a wide range of fields: from materials to devices, circuits, systems and applications. The impact of this topic was showcased by the ever-increasing number of publications in topical journals and conference proceedings as well as the numerous targeted workshops and symposia organised. The need for more transdisciplinary interactions is however acknowledged for further progressing the state-of-art. MEMRISYS addressed this need by consolidating the underlying research communities in materials science, electron devices, circuits and systems, computation and neuromorphic engineering in a single international conference that will bring a new holistic view of developments in the field.
Year(s) Of Engagement Activity 2017
URL http://memrisys2017.eventsadmin.com/Home/Welcome
 
Description Outreach activities in Nanotechnology 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact We have delivered 3 outreach events for introducing the NanoWorld to primary school students. This was so successful that attracted the interest of the RAEng with whom we co-delivered one of the events and also Nature Nanotechnology who praised our approach by commissioning an article that describes our unique activity (Nature Nanotechnology, vol. 12, 832, 2017).
Year(s) Of Engagement Activity 2017,2018,2019
URL https://youtu.be/QoBOdwJ9ubc