EPSRC Centre for Innovative Manufacturing in Medical Devices

Lead Research Organisation: University of Leeds
Department Name: Mechanical Engineering

Abstract

The EPSRC Centre in Innovative Manufacturing in Medical Devices will research and develop advanced methods for functionally stratified design and near patient manufacturing, to enable cost effective matching of device function to the patient needs and surgical environment. This will deliver "the right product, by the right process to the right patient at the right time" to an enhanced standard of reliability and performance. The centre will research and develop:
1) Functionally stratified design systems, which will be initially applied to existing device manufacturing processes and subsequently to the manufacture of scaffolds, developing novel pre-clinical simulation methods, which match implant design to patient function, delivering a cost effective Stratified Approach for Enhanced Reliability (SAFER)
2) Innovative near patient manufacturing processes, enabled by stratified and individualised definitions of patient need, to provide a more cost effective approach to personalised devices.

The two flagship challenges will be integrated with the key platform capabilities, across the centre to generate, for the first time, a closed loop design and manufacturing framework for medical devices to deliver enhanced performance and reliability. These innovative design and manufacturing advances will focus in the first instance on class 3 medical devices for musculoskeletal disease, where the cost of device failure and need for throughout life reliability are high.

The National Centre will develop, lead and integrate an international network of industrialists, academics, clinicians and regulatory body representatives in order to support the musculoskeletal medical device manufacturing industry to deliver the innovative design and manufacturing challenges and implement the outcomes into manufacturing practice in a global highly regulated market. The Centre will create the research infrastructure, tools and methods, expertise and suitably qualified personnel to support continued innovation and growth of the medical device manufacturing sector in the UK. To do so, the Centre will work across the EPSRC priority research areas "Manufacturing the Future" and "Towards next generation healthcare," drawing upon capabilities and collaborating with existing centres of excellence. The Centre will provide a platform for fundamental innovative device manufacturing research and promote its rapid exploitation by industry through outreach and translation activities and a generic platform for diversification into other technologies.

It will grow the UK's research capability in medical device manufacturing research to underpin the development of next generation medical devices and the development of high quality manufacturing processes to provide cost effective, reliable and effective devices. It will be applied to enhanced manufacturing of existing devices such as joint replacements and support manufacture of new products and biomaterial scaffolds. The Centre will operate across five leading academic centres of excellence in the field. The Centre will be led by Leeds University (Fisher, Williams, Ingham, Wilcox, Jennings and Redmond) and will be supported by collaboration from Newcastle (Dalgarno and McKaskie), Nottingham (Grant, Ahmed and Warrior), Sheffield (Hatton) and Bradford (Coates). The Centre will work closely with major manufacturers and users including surgeons who see at first hand the challenges of patient and surgical variation. The Centre will provide a platform for developing fundamental medical device manufacturing science and promote its rapid exploitation by industry.

Planned Impact

Who will benefit?
The Centre will grow the UK's research capability in medical device manufacturing research to underpin the development of next generation medical devices and the development of high quality manufacturing processes to provide cost effective, reliable and effective devices. The approach has been co-created to shape and define medical device manufacturing research needs. However, the outcomes of the centre will extend beyond these users to a wide platform of beneficiaries that will include:

UK Medical Device Companies: The Centre will develop, lead and integrate an international network of industrialists, academics, clinicians and regulatory body representatives in order to support the UK musculoskeletal medical device manufacturing industry to deliver the innovative design and manufacturing challenges and implement the outcomes into manufacturing practice in a global highly regulated market. Through this approach the Centre will benefit and support the UK medical device industry to develop and implement new manufacturing methods for existing and new next generation devices. The Centre intends to work with the regulatory bodies (MHRA, BSI and NICE) as well as the joint registries that collate data on post-market surveillance of medical devices. This approach will allow better sharing of intelligence and new research findings amongst the regulatory community in the UK and more widely to ensure regulatory requirements continue to be defined to improve patient outcomes and deliver affordable healthcare.

Individual Patients and the NHS: The outcomes from the Centre will provide new methods and systems and intelligence on the requirements of different patient groups and individual patient needs that will lead to enhanced reliability and performance of devices in the patients who receive them. This will result in better recovery and restoration of function leading to quality of life benefits in those patients. Furthermore, the delivery of stratified and personalised medical devices will lead to significant reduction in healthcare costs through earlier, better and, where possible, minimal invasive interventions, and through reduced need for revision and replacement.

The UK Innovation Ecosystem: The Centre intends to develop a defined and connected innovation system that will develop fundamental research and connect to other national centres to ensure the value of that research can be utilised to benefit UK companies, healthcare providers and ultimately patients. The Centre intends to work with other EPSRC Centres to maximise impact and ensure the research findings can be shared with and used in other sectors. The Centre will also fit within the UK innovation landscape to support the Cell Therapies and High Value Manufacturing Catapults who can benefit from and provide support for technologies developed through the Centre.

The Economy in the UK: The medical technologies sector in the UK is broad and diverse with many SMEs who need access to world leading research that can support their growth and lead to wealth creation n the UK. The Centre will aim to foster collaboration between researchers, clinicians, regulators and end users to allow better access to and sharing of research findings for innovative device design and manufacture. The expertise, know-how and IP created by the Centre will underpin the competiveness of the UK business base.

How will they benefit?
There is a demand across all markets for increased reliability and assurance of throughout lifetime performance of medical devices. New developments in regulation and compliance will require enhanced pre-clinical simulation and a fuller evaluation of the wide range of conditions under which devices have to perform. The Centre will provide new approaches to design and manufacturing and new materials technologies to meet these needs within the existing cost envelope; supported by less invasive surgery and shorter hospital stays.

Organisations

Publications

10 25 50

publication icon
Tcacencu I (2018) Osseointegration of porous apatite-wollastonite and poly(lactic acid) composite structures created using 3D printing techniques. in Materials science & engineering. C, Materials for biological applications

publication icon
Thompson A (2017) X-ray computed tomography and additive manufacturing in medicine: a review in International Journal of Metrology and Quality Engineering

 
Description MeDe Innovation was created to lead the UK in the innovative manufacture of implants, biomaterials and new regenerative devices for the treatment of musculoskeletal disease and related disorders.
Our definition of 'manufacturing' spans the entire value chain, from creative idea and patient need, right through to manufactured products and services delivered to the patient and the market. We aim to advanced knowledge and technology towards creating lasting social value, as well as supporting UK manufacturing in growing its share of a global market that will be worth $75 billion by 2020.
With an ageing population that expects to be more active for longer, we must deliver 21st century products and services and personalised interventions that last for '50 years after 50'. This requires an exceptional underpinning research base, the right collaborations, the vision to see how new advancements in different technologies can be combined into new multifunctional products and services to address clinical and industry challenges, and to develop people who are equipped with the right skills and experience to deliver.
Four years into our funding, we have many successes to celebrate.
We've built a strong community from which we can draw together the best collaborations possible to address specific challenges in research translation and delivery of social and economic benefits.
Our core partnership of five universities - Leeds, Sheffield, Newcastle, Bradford and Nottingham - now collaborates with 48 universities around the world.
Our 17 original industrial partners have now grown to over 30. These relationships deliver mutual benefits in terms of research advances and commercial success and have leveraged a further £64m of funding and investment of which £38m are new external grants awarded in the last four years.
Through our international partnerships with both universities and companies we can offer our staff and those of our partners, greater opportunities for of skills development at all professional levels. These events, conferences, training workshops, research collaborations and secondments are ensuring that people and businesses can thrive.
Our work with DePuy Synthes is just one example of this success. Through this partnership, we have delivered experimental and computational simulation systems for artificial joints that are unrivalled, and our natural knee simulator developed in collaboration with Simulation Solutions for tissue sparing interventions is a world first. Our long-standing relationship has seen DePuy Synthes expand its new research, development and technical centre in Leeds, securing approximately 500 jobs including 70 industrial R&D positions.
All of these achievements directly match the key elements of the government's Industrial Strategy on science, research and innovation that seek to enable the UK to harness its world-leading science base to drive economic growth.
The Centre has grown its funding through the development of research and innovation activities, actively seeking external funding to deliver the translation of research.
The success of our approach is evident: from a core grant of £9m, our total funding to date has now exceeded £70m.
As a powerhouse for innovative manufacturing research, we attract resources and funding and from a variety of sources, including the public sector, Universities charities and industry and we have been successful in aligning over £64m of investment and new funding to the strategic goals of the centre . To date, our collaborative approach to developing research projects has seen us be successful in securing £38m in new external research awards in the last four years to support the on going research activities in the centre.
We will continue to work intensively with our partners to jointly respond to funding opportunities, and to strengthen and expand the distinctive collaborative approaches that underpin the Centre's success. Below we provide short descriptions of different research areas

Joint Replacements.
Artificial hip and knee joints are among the most successful orthopaedic surgical interventions today, but they do not meet the needs of an increasingly active, ageing population. This has created a growing demand and expectation that joint replacements should last their lifetime, yet for patients in their 50s, the revision rate for hip replacement over their lifetime is 30% - and for knee replacements, this rises to 35%.
Improving the reliability and lifetime of joint replacements involves not just the application of new and emerging technologies to existing devices and the design and manufacture of new products; crucially, it also needs to consider variations in surgical positioning and patient needs - and a much more sophisticated stratification of patient populations and activities.
These multiple variables present complex challenges to both researchers and to industry in addressing the growing demand for '50 active years after 50'.
To support the medical device industry's response to this global clinical and economic need, we are advancing methodologies for the simulation, design and preclinical testing of hip and knee prostheses. This is enabling us to increase the precision and reliability - and improve long-term outcomes - of hip and knee replacements and we're now taking similar approaches in developing methodologies for ankle joints and spinal interventions.
Our advanced simulation methodologies have been adopted by industry in the development of new prostheses and MeDe Innovation researchers have led and contributed to two new international standards for the pre-clinical testing of hip and knee replacements. Our collaboration with Simulation Solutions now sees our simulators being sold around the world.
Our experimental natural knee simulation system - the first of its kind - offers pre-clinical simulation of the biomechanical and tribological function of new tissue sparing devices we are developing, which will aid the design, manufacture and testing of new products.
Ultimately, we expect to see manufactured devices that are enhanced with digitally-enabled technologies that will aid their surgical positioning, performance and longevity. Our virtual simulation systems which are already being used to help design new products is one step towards that goal.

Acellular scaffolds.
Soft tissue damage to the knee is a common and debilitating problem, particularly for young and otherwise healthy adults who participate in sports. Our research seeks to produce a next-generation treatment for these types of injuries, which are currently repaired using autograft or allograft donations. Acellular biological scaffolds offer an off-the-shelf solution that can be used without taking tissue from other parts of a patient's body and so avoiding the additional damage this can cause.
They also do not carry the same risk of immunological rejection of grafts from donated tissue.
We are developing acellular scaffolds for osteochondral, ligament and meniscus repair and replacement. These include both single tissue scaffolds and composite scaffolds, comprising soft tissue and bone in a single graft, which helps to improve integration into the recipient site.
For such grafts to be used clinically, manufacturers need to be able to produce such scaffolds with well-defined properties that can be matched to the patient's needs. Our work has focused on refining the processes needed to reliably source, process and sterilise scaffolds without adversely affecting the biomechanical properties and the capacity for recellularisation following implantation.
The knowledge and processes developed under this theme are being used by our partners in ongoing clinical trials and to develop Good Manufacturing Practice processes by NHS Blood & Transplant Tissue & Eye Services.
There is still further work to be done on refining grafts so they can be better matched to patient populations by varying the size, shape and mechanical properties of the harvested tissue. Scaffolds can also be treated to increase or reduce the mechanical properties to more closely match the patient`s tissue. This will be done with the aim of providing a wider range of off-the-shelf solutions that are suitable for the patient's sex, size and lifestyle.

Non woven collagen scaffolds:
As the main structural protein in most hard and soft tissues in the human body, collagen has great potential for use as scaffolds in tissue engineering. It has low immunogenicity, a porous structure, good biocompatibility and will biodegrade, avoiding the need for surgical procedures to remove it at a later stage. Collagen scaffolds, however, lack mechanical strength and stability when hydrated, which limits their usability. Our research has sought to develop manufacturing processes that can overcome these limitations, while maintaining the other natural properties of collagen in a reliable way.
The multiscale manufacturing platform we have produced allows precise control of the physical properties of this important biomaterial so that performance can be customised to meet specific requirements. This allows the collagen to be produced in a wide range of formats and with physical properties that can be tuned to meet different clinical demands. This can be done either at the manufacturing stage or at the point of delivery in order to meet the needs of patients. Importantly, the collagen can be produced in non-woven formats that are already familiar to clinicians and patients, meaning there is no need to learn new techniques for manipulating these products.
The flexibility of our manufacturing platform has allowed us to work with clinicians on a number of different applications. Initially, we have developed solutions for guided bone repair in maxillofacial surgery and thicker scaffolds for use in wound care. We are now working towards studies that will aid the translation of these into the clinic. There is also work underway to investigate the use of collagen-based non-woven fabrics for bone repair at other sites. Our future work includes exploring the properties of the new photoactive atelocollagen materials produced by our platform, including their ability to control microbial activity.
Alongside this, we are continuing development of a wet-spinning manufacturing platform to ensure fibres can be produced consistently. We also hope to address the scalability of our manufacturing process as well as ensuring it meets Good Manufacturing Practice.

Multiphase fixation devices.
Repairs to hard tissue often require metallic pins, screws and plates to be surgically implanted to allow healing. These fixation devices can then require further surgery at a later stage to remove them. This carries inherent risks to the patient, so it is attractive to instead use fully resorbable devices that will be replaced over time by cells. One of the main hurdles to achieving this is the sudden degradation that can occur with resorbable devices, which can lead to failure of an entire device and prevent proper integration. Our research is developing manufacturing technologies for glasses where the resorption rate can be controlled to avoid this loss of mechanical properties too early. This has allowed us to create next-generation multi-phase materials and devices that can progressively be resorbed, allowing a gradual replacement of the composite fibres with cells. The initial applications are in orthopaedic fixation and repair, but we are also exploring other applications for these resorbable glasses. We have developed processes that can apply the glasses as coatings for medical implants and this work is now developing into new areas, such creating sacrificial layers or layers with antimicrobial activity. Another innovative manufacturing process we have developed also produces glass microspheres for use in repairing damaged bone tissue.
We are also developing computational models to produce three dimensional images from a range of different medical imaging technologies. These detailed 3D models can then be used to enable the design and manufacture of patient specific implants or surgical tools. The imaging can also be used post-surgery to assess the performance of an implant. We have been working with partners in business to develop medical devices using this technology and have applied for a patent.

Minimally invasive implantation of bioactive materials
Repairing osteochondral damage can often require open surgery, which carries greater risks of infection and longer recovery times for patients. Creating suitable devices that strong enough to be load-bearing yet small enough to be delivered through minimally invasive procedures is challenging. Our work has focused on developing manufacturing methods to produce new devices that might overcome these difficulties.
This has included the manufacture of membranes with enhanced biofunctionality for use in osteochondral repair. By using innovative assembly techniques, we have been able to deliver new properties to these membranes, such as enhancing bone tissue regeneration and drug delivery. This work has led to an unexpected commercial translation as an innovative device for tissue regeneration in oral medicine.
Another approach has been to develop new economic methods for producing nanoscale bioactive materials that can be used as injectable bone graft substitutes. We are also now exploring ways of adding new biofunctionality to these commercially important products.
Infections associated with implanted devices can also be a serious risk to patients and are a significant burden health service resources. In an attempt to address this, we have collaborated with partners in Europe on research to design new generations of bioactive glasses with antimicrobial properties. We are now working with commercial partners to develop these further.
We have also developed 3D printing techniques to create bone replacement devices in a range of bioceramic materials that have load bearing capacity while still supporting bone growth. This work has been performed in collaboration with international partners and our work in the future with industry will focus on developing the ability to produce specific devices at a large scale.


Processes for in-clinic manufacture
There is currently no treatment for patients with small defects in hip or knee joints, often meaning these deteriorate over a number of years, leading to osteoarthritis. To repair such defects and prevent deterioration requires implants that can be delivered with minimally invasive surgery.
Our research is developing methods for rapidly and reliably combining cells with structural biomaterials so it is possible to create musculoskeletal implants that can be delivered without the need for major surgery. The aim is for implants to be produced, incorporating cells harvested from the patient, as they are being built in the clinic, potentially even during surgery.
To do this, however, requires synthetic and biological materials to be processed alongside each other, reliably and at speed. We are developing cell printing techniques that will enable load bearing, bioactive, personalised osteochondral implants to be produced to meet these demands in the clinic. Part of this has involved developing novel bio-inks that can be co-processed with materials to create implants. This work has also led to a new strand of work developing possible replacements for animal models of osteoarthritis.
Our research has also included developing a new way to 3D print cell-laden hydrogels that can be used to create gel based structures with high precision. Looking forward, we aim to develop bioprinters to the point where they can be used as genuine plug and play systems for use in the clinic. This will require collaborations with clinicians and colleagues in the biosciences to validate and trial the technology. We have also been researching techniques to create solid and cannulated fixation devices that can be programmed to change shape in situ on exposure to body temperature or body fluid. The aim is to create devices that can used to fix soft tissue to bone or bone to bone
Exploitation Route MeDe Innovation is engaged at every stage of the innovation and translation pipeline, from initial ideas and concepts, through developing methods, technologies and intellectual property, to collaborating with device manufacturers and clinicians to deliver new products.
Our focus has always been on supporting continuous innovation: establishing and nurturing an innovation pipeline that enables ideas to flourish and supports researchers to develop those ideas through different Technology Readiness Levels (TRLs) towards commercial development. To date, there are more than 90 projects in our portfolio, progressing from TRL 1 to TRL5 and beyond.
Through our network, we are able to support innovation in a wider sense too, through sharing information about available funding opportunities, and promoting Knowledge Transfer Partnerships and CASE awards to encourage collaboration. We support academic and industry secondments, to stimulate knowledge sharing throughout the sector and work with businesses to translate knowledge through an extensive range of consultancy work and contracts.
Our Early Career Researcher Network is vital to the early-stage process: developing the next generation of researchers in medical device manufacture is essential if we are to continue to produce innovative ideas and projects. Initiatives such as our Sandpit events, and post-graduate secondments have provided valuable opportunities for our ECRs to develop projects; but equally important is our ECR Forum, which links members together to share ideas and form partnerships through workshops, presentations and virtual networking. The progression of the careers of our highly trained researchers, moving on to new positions in industry regulatory bodies and other research centres and Universities is a key part of our successful innovation and translation
Further along the innovation pipeline, we've been able to accelerate the commercial development of several of our technologies and apply the very latest innovation management practice through collaboration with the Medical Technologies IKC.
Sectors Healthcare,Manufacturing, including Industrial Biotechology

URL http://imbe.leeds.ac.uk
 
Description The EPSRC Centre for Innovative Manufacturing in Medical Devices, is developing new methodologies for stratified and personalised design and manufacture of innovative technologies and products, focusing initially on the musculoskeletal system to support 50 active years after fifty ® in a healthy ageing population. Research addresses all elements of the manufacturing value chain from product concept to patient delivery and adoption: focusing on novel virtual models for functional simulation; design and prediction of performance; near patient manufacturing; and enhanced pre-clinical test methods using Stratified Approaches For Enhanced Reliability - SAFER. Outcomes, Translation and impact, progression beyond TRL3 Translation of knowledge and technology Research and technology created in the centre has been advanced beyond TRL3 by our industry partners to support design development and manufacture and to create commercial value. These include development projects by our partners DePuy Synthes, Invibio, NHS Blood & Transplant, Tissue Regenix Group Plc, Biocomposites, Simulation Solutions, Mathys AG, Ceramsys, Surgical Dynamics,JRI which have been supported by the centre. We have created six cases studies to describe this translation and impact. Knowledge is also translated and business has been assisted through an extensive range of consultancy work and contracts. Inward investment to develop MeDe knowledge and IP, beyond TRL 3 in the UK Partners DePuy Synthes, Invibio, Tissue Regenix Group Plc and NHS Blood & Transplant have invested in technology development and manufacturing facilities in the UK, alongside investments in new product development programmes and the establishment of new manufacturing processes. Policy advice, Standards development, Expert advice, Advocacy The centre has led and contributed to the development of two new international standards for pre-clinical testing of joint replacements, have contributed to policy work and advice through the RAEng, EPSRC. The Director sits on the LEPs business and Innovation Growth panel. Jennings chairs the ISO standards committee, Wilcox sits on RAEng Biomedical Engineering Group. Consultancy advice is provided in an ongoing basis to six companies. Work has led to new international standard for pre clinical testing hip prostheses The Role of the Centre Advisory Board The Advisory Board has industry, clinical, regulatory and academic members.it was enlarged on initial creation to ensure membership from manufacturing industry alongside the device, regulatory and clinical perspective. Its key functions include: • An independent national and international perspective • Oversight of strategy and plans • Monitoring performance • Advising on translation and outcomes • Advising on future strategy MeDe Innovation is engaged at every stage of the innovation and translation pipeline, from initial ideas and concepts, through developing methods, technologies and intellectual property, to collaborating with device manufacturers and clinicians to deliver new products. Our focus has always been on supporting continuous innovation: establishing and nurturing an innovation pipeline that enables ideas to flourish and supports researchers to develop those ideas through different Technology Readiness Levels (TRLs) towards commercial development. To date, there are more than 90 projects in our portfolio, progressing from TRL 1 to TRL5 and beyond. Through our network, we are able to support innovation in a wider sense too, through sharing information about available funding opportunities, and promoting Knowledge Transfer Partnerships and CASE awards to encourage collaboration. We support academic and industry secondments, to stimulate knowledge sharing throughout the sector and work with businesses to translate knowledge through an extensive range of consultancy work and contracts. Our Early Career Researcher Network is vital to the early-stage process: developing the next generation of researchers in medical device manufacture is essential if we are to continue to produce innovative ideas and projects. Initiatives such as our Sandpit events, and post-graduate secondments have provided valuable opportunities for our ECRs to develop projects; but equally important is our ECR Forum, which links members together to share ideas and form partnerships through workshops, presentations and virtual networking. The progression of the careers of our highly trained researchers, moving on to new positions in industry regulatory bodies and other research centres and Universities is a key part of our successful innovation and translation Further along the innovation pipeline, we've been able to accelerate the commercial development of several of our technologies and apply the very latest innovation management practice through collaboration with the Medical Technologies IKC. Examples of impact of our research and and technical outcomes and industry uptake in their development and manufacturing processes and the creation of ecomonic value in the UK include, Full impact case studies are available for each of these cases on request examples are provide below New international standard for hip simulation New hip joint simulator Simulation Solutions New knee joint simulator Simulation Solutions Natural knee joint simulator Simulation Solutions Support for All polymer knee being developed by InVibio Support for development new ceramic hip Mathys Support for development bone void filler Biocomposites Support for new hip joint development DePuy Support for new knee joint replacements and the evaluation of existing products and new product development with DePuySynthes Pre clinical definitions and recommendations for use of joint replacements including, surgical positioning, patient activities and their effect on clinical performance of prostheses Support for development and manufacture new acellular bone patellar bone graft NHSBT Support for development acellular ligament graft Tissue Regenix completed clinical trial
First Year Of Impact 2015
Sector Healthcare,Manufacturing, including Industrial Biotechology
Impact Types Societal,Economic

 
Description Chair of ISO TC150/SC4 Bone and Joint Replacements
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact New international standards published, including a test method developed at the University of Leeds (ISO14242-4).
 
Description LCR BIG Panel
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Membership of a guideline committee
Impact Membership of local economic partnership Leeds city region , west Yorkshire combined authority business Innovation growth Panel - special advisor on research innovation Universities
 
Description Med ical technology science and innovation audit
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
Impact Leadership of Medical Technology science an dInnovation audit, Leeds City region Plus
 
Description Presented 'provocation' and participated in Wellcome Health Exchange - Wellcome Trust discussion on healthy aging research chaired by Eliza Manningham-Buller (Ruth Wilcox)
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
 
Description Provided evidence and represented RAEng at Royal College of Surgeons Commission on the Future of Surgery (Ruth Wilcox)
Geographic Reach National 
Policy Influence Type Contribution to a national consultation/review
URL https://futureofsurgery.rcseng.ac.uk/?_ga=2.204377936.1302407628.1552062378-663961335.1547802634
 
Description Versus Arthritis Research Advisory Group - Ruth Wilcox
Geographic Reach National 
Policy Influence Type Participation in a guidance/advisory committee
 
Description international standards committee chair
Geographic Reach Asia 
Policy Influence Type Membership of a guideline committee
Impact international pre clinical testing standards
 
Description A*Star-University of Sheffield collaborative PhD studentship
Amount £85,000 (GBP)
Organisation A*STAR - Southampton Research Attachment Programme 
Sector Academic/University
Country United Kingdom
Start 09/2016 
End 08/2019
 
Description ARUK
Amount £700,000 (GBP)
Organisation Versus Arthritis 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2016 
End 09/2021
 
Description Active aGeIng and Osteoporosis: The next challenge for smarT nanobiOmaterials and 3D Technologies
Amount € 5,660,096 (EUR)
Funding ID 814410 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 01/2019 
End 02/2023
 
Description Arthritis Research UK Tissue Engineering Centre - Phase II
Amount £2,000,000 (GBP)
Funding ID 21156 
Organisation Versus Arthritis 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2016 
End 03/2021
 
Description Arthritis Research UK Translation
Amount £100,000 (GBP)
Funding ID 21501 
Organisation Versus Arthritis 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2017 
End 11/2018
 
Description Arthritis Research UK Translational Medical Technologies Proof of Concept Award
Amount £97,000 (GBP)
Funding ID 21161 
Organisation Versus Arthritis 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2015 
End 12/2016
 
Description BBSRC IAA- Proof of Concept, Molecular recycling as a strategy for regenerative medicine: local tissue response to a new biodegradable orthobiologics scaffold and effect on inflammation
Amount £25,000 (GBP)
Organisation University of Nottingham 
Sector Academic/University
Country United Kingdom
Start 01/2019 
End 07/2019
 
Description Biocomposites
Amount £200,000 (GBP)
Funding ID LMJ 
Organisation Biocomposites 
Sector Private
Country United Kingdom
Start 01/2013 
End 01/2016
 
Description Biomedical research unit
Amount £6,000,000 (GBP)
Funding ID Leeds musculoskeletal biomedical research unit 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2014 
End 03/2017
 
Description Bridging the Gaps
Amount £12,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 01/2017 
End 06/2017
 
Description Bridging the Gaps - Antimicrobial Resistance
Amount £40,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 03/2017 
End 07/2017
 
Description British Council Newton Researcher Links 'Healthcare Technologies for Aging Populations'
Amount £24,000 (GBP)
Funding ID 227337704 
Organisation British Council 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2016 
End 01/2017
 
Description CASE Studentship
Amount £54,000 (GBP)
Organisation Croda International 
Sector Private
Country United Kingdom
Start 10/2017 
End 09/2021
 
Description CASE Studentship Funding
Amount £35,000 (GBP)
Organisation AO Foundation 
Department AO Research Institute
Sector Charity/Non Profit
Country Switzerland
Start 10/2017 
End 09/2021
 
Description CASE Studentship Funding
Amount £60,000 (GBP)
Organisation Depuy International 
Sector Private
Country United Kingdom
Start 09/2017 
End 10/2021
 
Description CASE Studentship Industrial Contribution
Amount £30,000 (GBP)
Organisation Glass Technology Services 
Sector Private
Country United Kingdom
Start 10/2015 
End 09/2019
 
Description CASE Studentship Industrial Contribution
Amount £30,000 (GBP)
Organisation Alcyomics Ltd 
Sector Private
Country United Kingdom
Start 10/2015 
End 09/2019
 
Description CASE Studentship Industry Contribution
Amount £30,000 (GBP)
Organisation QuantuMDx Group Ltd. 
Sector Private
Country United Kingdom
Start 09/2015 
End 10/2019
 
Description CCTMIH Manufacture of Future Fibrous Products Research Fellowship
Amount £250,000 (GBP)
Organisation University of Leeds 
Sector Academic/University
Country United Kingdom
Start 03/2019 
End 03/2021
 
Description CDT 2014-22
Amount £4,000,000 (GBP)
Funding ID CDT TERM 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 06/2014 
End 09/2022
 
Description Capital equipment CDT
Amount £240,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 11/2015 
End 04/2019
 
Description Capital equipment hip and knee simulators
Amount £920,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 04/2015 
End 04/2020
 
Description Catalyst Medical Technologies
Amount £3,000,000 (GBP)
Organisation Higher Education Funding Council for England 
Sector Public
Country United Kingdom
Start 10/2015 
End 10/2018
 
Description China-UK Researcher Links Workshop on Healthcare Technologies
Amount £1,800 (GBP)
Organisation University of Bradford 
Department University of Bradford: Newton Fund
Sector Academic/University
Country United Kingdom
Start 12/2016 
End 12/2016
 
Description Clothworkers Foundation/UoL - CCTMIH Equipment
Amount £500,000 (GBP)
Organisation University of Leeds 
Sector Academic/University
Country United Kingdom
Start 12/2018 
End 12/2019
 
Description Commercial sponsorship (Wilcock / nanoHA biocomp. Jan to Mar 2016)
Amount £6,127 (GBP)
Organisation Ceramisys 
Sector Private
Country United Kingdom
Start 01/2016 
End 03/2016
 
Description Confidence in Concept
Amount £29,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2017 
End 03/2018
 
Description Contract Research
Amount £51,500 (GBP)
Funding ID IDEXXX 
Organisation Sheffield Hallam University 
Sector Academic/University
Country United Kingdom
Start 05/2014 
End 10/2016
 
Description Contract Research (Nobel Biocare)
Amount £137,826 (GBP)
Organisation Nobel Biocare 
Sector Private
Country United Kingdom
Start 10/2015 
End 09/2019
 
Description DTC 208-2017
Amount £7,000,000 (GBP)
Funding ID DTC 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 06/2008 
End 09/2017
 
Description DTP
Amount £2,000,000 (GBP)
Funding ID DTP 
Organisation DePuy Synthes 
Sector Private
Country United States
Start 01/2014 
End 01/2016
 
Description Depuy
Amount £300,000 (GBP)
Organisation Depuy International 
Sector Private
Country United Kingdom
Start 01/2016 
End 01/2017
 
Description EPSRC - VaxHub Thermostable Formulations
Amount £192,000 (GBP)
Organisation University of Leeds 
Sector Academic/University
Country United Kingdom
Start 05/2019 
End 07/2020
 
Description EPSRC Centre for Doctoral Training in Polymers and Soft Matter
Amount £120,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 09/2015 
End 08/2019
 
Description EPSRC Centres for Doctoral Training
Amount £361,000 (GBP)
Funding ID EP/L01534X/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 04/2014 
End 09/2022
 
Description EPSRC Centres for Doctoral Training Capital Award
Amount £110,000 (GBP)
Funding ID EP/L01534X/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 07/2014 
End 03/2015
 
Description EPSRC DTC TERM studentship now MeDe associated (with industrial CASE partners) - Joss Atkinson Ceramisys top up
Amount £5,250 (GBP)
Organisation Ceramisys 
Sector Private
Country United Kingdom
Start 06/2014 
End 07/2016
 
Description EPSRC DTC TERM studentship now MeDe associated (with industrial CASE partners) - Joss Atkinson JRI top up
Amount £5,250 (GBP)
Organisation JRI Orthapaedics 
Sector Private
Country United Kingdom
Start 06/2014 
End 07/2016
 
Description EPSRC Healthcare Impact Partnership
Amount £904,074 (GBP)
Funding ID EP/R024324/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 07/2018 
End 06/2021
 
Description EPSRC IAA
Amount £75,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 04/2018 
End 04/2019
 
Description EPSRC IAA - Proof of Concept,Novel water resistant Coupling Agent for Bioresorbable Fibre Reinforced Composites
Amount £30,000 (GBP)
Organisation University of Nottingham 
Sector Academic/University
Country United Kingdom
Start 06/2018 
End 01/2019
 
Description EPSRC cartilage programme
Amount £4,600,000 (GBP)
Funding ID EPG01121721 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 06/2009 
End 06/2015
 
Description EPSRC i-sense Exploratory Project Funding
Amount £89,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 01/2016 
End 04/2017
 
Description European Research Council advanced award
Amount £2,000,000 (GBP)
Funding ID Proposal 267114 
Organisation European Research Council (ERC) 
Sector Public
Country Belgium
Start 04/2011 
End 04/2016
 
Description Feasibility testing of SelfGel Powder Spray
Amount £20,000 (GBP)
Organisation Grow MedTech 
Sector Academic/University
Country United Kingdom
Start 03/2019 
End 06/2019
 
Description HEFCE Catalyst PhD industrial PhD research extension with Ceramisys (for Wilcock)
Amount £27,000 (GBP)
Organisation Higher Education Funding Council for England 
Sector Public
Country United Kingdom
Start 07/2015 
End 12/2015
 
Description HERMES Fellowships
Amount £23,000 (GBP)
Organisation University of Nottingham 
Department Higher Education Innovation Fund
Sector Academic/University
Country United Kingdom
Start 10/2016 
End 03/2017
 
Description Healthcare Impact Partnership
Amount £1,025,492 (GBP)
Funding ID EP/N02480X/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 06/2016 
End 05/2021
 
Description Healthcare Technologies Programme Grant
Amount £3,962,447 (GBP)
Funding ID EP/N02480X/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 10/2016 
End 09/2021
 
Description Impact Acceleration Account
Amount £132,287 (GBP)
Funding ID BRNDOG 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 12/2015 
End 03/2017
 
Description Impact Accelerator Account: Proof of Concept
Amount £90,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 12/2015 
End 03/2017
 
Description Industrially funded research
Amount £7,800 (GBP)
Funding ID 150359 (URMS code) 
Organisation Dermtreat 
Sector Private
Country Denmark
Start 11/2016 
End 10/2017
 
Description Industry Biocomposites
Amount £150,000 (GBP)
Organisation Biocomposites 
Sector Private
Country United Kingdom
Start 07/2015 
End 07/2016
 
Description Industry Invibio
Amount £300,000 (GBP)
Organisation Invibio 
Sector Private
Country United Kingdom
Start 10/2015 
End 10/2017
 
Description Innovate UK
Amount £1,016,000 (GBP)
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start 09/2017 
End 02/2019
 
Description Innovative Solution for Polyp-lifting
Amount £4,989 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 03/2019 
End 05/2019
 
Description Invention for Innovation (i4i) Challenge Awards
Amount £1,121,425 (GBP)
Funding ID II-C3-0714-20001 
Organisation National Institute for Health Research 
Department NIHR i4i Invention for Innovation (i4i) Programme
Sector Public
Country United Kingdom
Start 10/2015 
End 09/2018
 
Description Knowledge Transfer Partnership
Amount £173,000 (GBP)
Funding ID KTP006777 
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start 12/2016 
End 06/2019
 
Description Leeds Musculoskeletal Biomedical Research Centre
Amount £6,000,000 (GBP)
Organisation University of Leicester 
Department NIHR Biomedical Research Centre
Sector Hospitals
Country United Kingdom
Start 04/2017 
End 03/2022
 
Description MRC Confidence in Concept Transitional Funding
Amount £75,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2016 
End 08/2017
 
Description MeDe Innovation Early Career Researchers Collaborative Funding
Amount £5,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 03/2017 
End 08/2017
 
Description MeDe Innovation Early Careers Researchers Grant to fund travel to secondment to clinic for Katherine Pitrolino
Amount £800 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 01/2017 
End 01/2018
 
Description Mecical technologies Innovation and Knowledge Centre Phase 2 Regenerative Devices
Amount £4,000,000 (GBP)
Funding ID EP/N00941X/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 07/2015 
End 07/2020
 
Description Medcial engineering centre
Amount £160,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 07/2015 
End 07/2019
 
Description Medical engineering centre
Amount £4,200,000 (GBP)
Funding ID WELMEC 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2014 
End 09/2015
 
Description Microfluidic Co-cultures for OA Modelling
Amount £96,000 (GBP)
Funding ID NS/A000051/1 
Organisation National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) 
Sector Public
Country United Kingdom
Start 01/2017 
End 06/2017
 
Description Microfluidic Co-cultures for OA Modelling (CRACKITOC-PI-11) Phase II
Amount £1,000,000 (GBP)
Funding ID NC/C016102/1 
Organisation National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) 
Sector Public
Country United Kingdom
Start 10/2018 
End 09/2021
 
Description NHSBT
Amount £200,000 (GBP)
Funding ID EI 
Organisation NHS Blood and Transplant (NHSBT) 
Sector Public
Country United Kingdom
Start 01/2014 
End 01/2017
 
Description Newcastle University MSE Equipment Fund
Amount £80,000 (GBP)
Organisation Newcastle University 
Sector Academic/University
Country United Kingdom
Start 01/2014 
End 07/2014
 
Description ORUK Studentship
Amount £70,000 (GBP)
Organisation Orthopaedic Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2016 
End 12/2019
 
Description Optimising knee therapies
Amount £4,000,000 (GBP)
Funding ID EP/P001076/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 09/2016 
End 09/2021
 
Description Regener8 IKC PoC funding for project entitled "Manufacturing Bone Tissue Using Resorbable Porous Calcium Phosphate Microspheres Loaded with Autologous Stem Cells"
Amount £98,778 (GBP)
Funding ID EP/G032483/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 10/2013 
End 10/2014
 
Description Research
Amount £70,000 (GBP)
Organisation The Clothworkers' Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2017 
End 09/2020
 
Description Royal Academy of Engineering Fellowship
Amount £20,000 (GBP)
Funding ID 1314RECI013 
Organisation Royal Academy of Engineering 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2014 
End 05/2015
 
Description Royal Society Newton Advanced Fellowship
Amount £111,000 (GBP)
Funding ID NA150222 
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2015 
End 08/2018
 
Description SelfGel technology: Polymer free and temperature independent bioadhesive in-situ gelling system UK ICURe Award
Amount £35,000 (GBP)
Funding ID IC1-20 
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start 07/2018 
End 09/2018
 
Description Studentship
Amount £49,659 (GBP)
Organisation University of Nottingham 
Sector Academic/University
Country United Kingdom
Start 10/2016 
End 09/2019
 
Description Studentship plus consumables
Amount £72,000 (GBP)
Organisation Zimmer Biomet 
Sector Private
Country United States
Start 10/2016 
End 09/2019
 
Description Tissue regenix
Amount £60,000 (GBP)
Funding ID EI 
Organisation Tissue Regenix Ltd 
Sector Private
Country United Kingdom
Start 01/2016 
End 01/2018
 
Description University of Bradford match for EPSRC Capital funding grant
Amount £684,000 (GBP)
Organisation University of Bradford 
Sector Academic/University
Country United Kingdom
Start 03/2014 
End 03/2018
 
Description University of Bradford match funding for EPSRC grant
Amount £160,000 (GBP)
Organisation University of Bradford 
Sector Academic/University
Country United Kingdom
Start 01/2014 
End 10/2017
 
Description University of Bradford match staff funding for EPSRC Capital grant
Amount £1,320,000 (GBP)
Organisation University of Bradford 
Sector Academic/University
Country United Kingdom
Start 01/2014 
End 03/2018
 
Description University of Sheffield PhD studentship (no 1 to MeDe Innovation)
Amount £65,000 (GBP)
Organisation University of Sheffield 
Sector Academic/University
Country United Kingdom
Start 09/2016 
End 08/2019
 
Description University of Sheffield PhD studentship (no. 2 to MeDe Innovation)
Amount £65,000 (GBP)
Organisation University of Sheffield 
Sector Academic/University
Country United Kingdom
Start 09/2016 
End 08/2019
 
Description WEL
Amount £80,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2015 
End 09/2018
 
Description White Rose Mucosal Drug Delivery Network
Amount £10,000 (GBP)
Organisation White Rose University Consortium 
Sector Academic/University
Country United Kingdom
Start 09/2017 
End 09/2018
 
Description contract
Amount £5,000 (GBP)
Organisation JRI Orthapaedics 
Sector Private
Country United Kingdom
Start 04/2017 
End 04/2017
 
Description depuy
Amount £250,000 (GBP)
Organisation Depuy International 
Sector Private
Country United Kingdom
Start 01/2017 
End 01/2018
 
Description epsrc
Amount £1,000,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 07/2015 
End 07/2020
 
Description invibio
Amount £400,000 (GBP)
Funding ID LMJ 
Organisation Invibio 
Sector Private
Country United Kingdom
Start 01/2014 
End 12/2016
 
Description invibio
Amount £200,000 (GBP)
Organisation Invibio 
Sector Private
Country United Kingdom
Start 12/2016 
End 12/2018
 
Description lmbrc
Amount £7,500,000 (GBP)
Organisation National Institute for Health Research 
Department NIHR Biomedical Research Centre
Sector Public
Country United Kingdom
Start 04/2017 
End 04/2022
 
Description mathys
Amount £400,000 (GBP)
Funding ID LMJ 
Organisation Mathys 
Sector Private
Country Switzerland
Start 01/2014 
End 01/2016
 
Description senior investigator
Amount £100,000 (GBP)
Funding ID LMBRU 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2014 
End 04/2015
 
Title Ankle joint simulation 
Description Ankle joint simulation system 
Type Of Material Model of mechanisms or symptoms - human 
Provided To Others? No  
Impact Wear prediction in total ankle joint 
 
Title Hip Joint simulator 
Description In vitro simulator for artificial hip joints 
Type Of Material Model of mechanisms or symptoms - in vitro 
Year Produced 2013 
Provided To Others? Yes  
Impact Method commercialised by Simulation Solutions 
 
Title Knee joint simulator 
Description artificial knee joint simulator 
Type Of Material Model of mechanisms or symptoms - in vitro 
Year Produced 2013 
Provided To Others? Yes  
Impact Simulator and simulation method commercialised by simulation solution 
 
Title Natural knee simulator 
Description Simulation system for natural knee 
Type Of Material Model of mechanisms or symptoms - in vitro 
Year Produced 2013 
Provided To Others? Yes  
Impact Simulator commercially available, Simulation Solutions 
 
Title Patellar simulation 
Description Simulation of mechanics and wear of patellae femoral joint 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2015 
Provided To Others? Yes  
Impact Determination of wear in patellar femoral joint 
 
Title natural hip simulator 
Description Simulation system for natural hip 
Type Of Material Model of mechanisms or symptoms - mammalian in vivo 
Year Produced 2014 
Provided To Others? Yes  
Impact System commercially availa le from Simulation Solutions 
 
Title Biomechanical and biotribological simulation model natural hip 
Description Biomechanical and biotribological model of natural hip 
Type Of Material Computer model/algorithm 
Year Produced 2013 
Provided To Others? Yes  
Impact used in follow on research 
 
Title Biomechanical model of functional spinal unit 
Description model of functional spinal unit 
Type Of Material Computer model/algorithm 
Year Produced 2014 
Provided To Others? Yes  
Impact used in follow on research 
 
Title Biotribological model naturala knee 
Description Biotribological model natural knee 
Type Of Material Computer model/algorithm 
Year Produced 2014 
Provided To Others? Yes  
Impact Used in follow on research on regenerative devices 
 
Title Combined Wear and Ageing of Ceramic-on-Ceramic Bearings in Total Hip Replacement under Edge Loading Conditions 
Description Data associated with the paper "Combined Wear and Ageing of Ceramic-on-Ceramic Bearings in Total Hip Replacement under Edge Loading Conditions" 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/526/
 
Title Data Associated with "The effect of surgical alignment and soft tissue conditions on the kinematics and wear of a fixed bearing total knee replacement" 
Description Data associated with the paper "The effect of surgical alignment and soft tissue conditions on the kinematics and wear of a fixed bearing total knee replacement". This dataset contains: - Figure 3. The raw data for mean output AP displacement with the 95% CI for each alignment condition under the stiff knee, preserved PCL and resected PCL soft tissue conditions. - Figure 4. The raw data for mean output TR rotation with the 95% CI for each alignment condition under the stiff knee, preserved PCL and resected PCL soft tissue conditions. - Figure 5. The raw data for mean output AA rotation with the 95% CI for each alignment condition under the stiff knee, the preserved PCL and the resected PCL soft tissue conditions. - Figure 6. The raw data for Mean wear rates with 95% CI over 2 MC for the ideal, 4° varus, 14° rotational mismatch and 10° tibial slope alignment conditions for two soft tissue conditions. 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/661/
 
Title Data associated with "Influence of Third Body Particles Originating from Bone Void Fillers on the Wear of Ultra High Molecular Weight Polyethylene" 
Description The dataset contains material to supplement the paper "Influence of Third Body Particles Originating from Bone Void Fillers on the Wear of Ultra High Molecular Weight Polyethylene" including: wear rates of UHMWPE pins and surface roughness analysis of cobalt chrome plates using both the contacting Form Talysurf and the Bruker NPFlex. 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/47/
 
Title Data associated with "PEEK-OPTIMA (Trademark) as an Alternative to Cobalt Chrome in the Femoral Component of Total Knee Replacement: A Preliminary Study". 
Description The dataset contains material to supplement the paper "PEEK-OPTIMA (Trademark) as an Alternative to Cobalt Chrome in the Femoral Component of Total Knee Replacement: A Preliminary Study" including: wear rates of UHMWPE tibial components articulating against PEEK-OPTIMA (Trademark) and cobalt chrome femoral components under two kinematic conditions, surface roughness analysis of PEEK-OPTIMA and cobalt chrome femoral components following wear simulation using a contacting Form Talysurf and measurements of the bulk lubricant temperature using a thermocouple. 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/74/
 
Title Data associated with "The Influence of Malalignment and Ageing Following Sterilisation by Gamma Irradiation in an Inert Atmosphere on the Wear of UHMWPE in Patella-Femoral Replacements". 
Description The dataset contains material to supplement the paper "The Influence of Malalignment and Ageing Following Sterilisation by Gamma Irradiation in an Inert Atmosphere on the Wear of UHMWPE in Patella-Femoral Replacements" including: wear rates of UHMWPE patellae, surface roughness of patellae using the contacting Form Talysurf and analysis of the size of the wear scars. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/111/
 
Title Data associated with "Third body wear of UHMWPE-on-PEEK-OPTIMA™" 
Description The dataset contains material to supplement the paper "Third body wear of UHMWPE-on-PEEK-OPTIMA™" including: measurements of the surface topography of PEEK and cobalt chrome plates following third body damage simulation with particles of PMMA cement and wear factors of UHMWPE against PEEK and cobalt chrome plates damaged both with cement particles and scratched with a diamond stylus. 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact Pre-clinical data that reduces need for in vivo animal models 
URL http://archive.researchdata.leeds.ac.uk/658/
 
Title Data associated with "Wear and Friction of UHMWPE-on-PEEK OPTIMA™" 
Description The dataset contains material to supplement the paper "Wear and Friction of UHMWPE-on-PEEK OPTIMA™" by Cowie R M., Briscoe A, Fisher J, Jennings LM (2019) J. Mech. Behav. Biomed. Mater. Volume 89, January 2019, Pages 65-71. https://doi.org/10.1016/j.jmbbm.2018.09.021 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/423/
 
Title Data associated with 'The Influence of Calcium Sulfate Bone Void Filler on the Third Body Damage and Polyethylene Wear of Total Knee Replacements' 
Description The dataset contains material to supplement the paper "The Influence of Calcium Sulfate Bone Void Filler on the Third Body Damage and Polyethylene Wear of Total Knee Replacements" including: wear rates and wear volumes of UHMWPE tibial components and surface roughness analysis of cobalt chrome femoral components following both third body damage simulation and experimental wear simulation using a contacting Form Talysurf. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/436/
 
Title Data associated with 'The Influence of Kinematic Conditions and Variations in Component Positioning on the Severity of Edge Loading andWear of Ceramic-on-Ceramic Hip Bearings' 
Description Data associated with the paper "The Influence of Kinematic Conditions and Variations in Component Positioning on the Severity of Edge Loading and Wear of Ceramic-on-Ceramic Hip Bearings". This dataset contains: - Figure 4. Dynamic separation (mean +/- 95% confidence limits, n = 3) of 36 mm diameter BIOLOX®delta ceramic-on-ceramic bearings under two axes and three axes of rotation conditions with 45 degree and 65 degree cup inclination angle conditions and 1, 2, 3 and 4 mm of medial-lateral translational mismatch conditions. - Figure 5. Load at the rim at separation (mean +/- 95% confidence limits, n = 3)of 36 mm diameter BIOLOX®delta ceramic-on-ceramic bearings under two axes and three axes of rotation conditions at 45 degree and 65 degree cup inclination angles with 1, 2, 3 and 4 mm of medial-lateral translational mismatch. - Figure 6. Severity of edge loading (mean ± 95% confidence limits, n = 3) of 36 mm diameter BIOLOX®delta ceramic-on-ceramic bearings under two axes and three axes of rotation conditions with 45 degree and 65 degree cup inclination angles and 1, 2, 3 and 4 mm of medial-lateral translational mismatch conditions (offset deficiency). - Figure 7. Wear rates (mean ± 95% confidence limits, n = 6) of 36 mm diameter BIOLOX®delta ceramicon-ceramic bearings under two axes and three axes of rotation conditions with 45 degree and 65 degree cup inclination angles and 4 mm of medial-lateral translational mismatch conditions. 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/665/
 
Title Data set for paper "Representing the Effect of Variation in Soft Tissue Constraints in Experimental Simulation of Total Knee Replacements" 
Description Data set for paper "Representing the effect of variation in soft tissue constraints in experimental simulation of total knee replacements". Data includes experimental results from a knee simulator that are represented in the figures and text of the paper. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/id/eprint/400
 
Title Dataset supporting the publication 'A Comprehensive Combined Experimental and Computational Framework for Pre-clinical Wear Simulation of Total Knee Replacements' 
Description A more robust pre-clinical wear simulation framework is required in order to simulate wider and higher ranges of activities, observed in different patient populations such as younger more active patients. Such a framework will help to understand and address the reported higher failure rates for younger and more active patients (National_Joint_Registry, 2016). The current study has developed and validated a comprehensive combined experimental and computational framework for pre-clinical wear simulation of total knee replacements (TKR). The input mechanical (elastic modulus and Poisson's ratio) and wear parameters and of the moderately cross-linked ultra-high molecular weight polyethylene (UHMWPE) bearing material were independently measured from experimental studies under realistic test conditions, similar to the loading conditions found in the total knee replacements.. The wear predictions from the computational wear simulation were validated against the direct experimental wear measurements for size 3 Sigma curved total knee replacements (DePuy, UK) in an independent experimental wear simulation study under three different daily activities; walking, deep squat, and stairs ascending kinematic conditions. The measured compressive mechanical properties of the moderately cross-linked UHMWPE material were more than 20% lower than that reported in the literature under tensile test conditions. The pin-on-plate wear coefficient of moderately cross-linked UHMWPE was significantly dependant of the contact stress and the degree of cross-shear at the articulating surfaces. The computational wear predictions for the TKR from the current framework were consistent and in a good agreement with the independent full TKR experimental wear simulation measurements, with 0.94 coefficient of determination of the framework. In addition, the comprehensive combined experimental and computational framework was able to explain the complex experimental wear trends from the three different daily activities investigated. Therefore, such a framework can be adopted as a pre-clinical simulation approach to optimise different designs, materials, as well as patient's specific total knee replacements for a range of activities. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/301/
 
Title Dataset supporting the publication 'A comparison between electromechanical and pneumatic controlled knee simulators for the investigation of wear of total knee replacements' 
Description More robust pre-clinical experimental wear simulation methods are required in order to simulate a wider range of activities, observed in different patient populations such as younger more active patients, as well as fully meeting and being capable of going well beyond the existing requirements of the relevant international standards. A new six station electromechanically driven simulator (Simulation Solutions, UK) with five fully independently controlled axes of articulation for each station, capable of replicating deep knee bending as well as other adverse conditions, which can be operated in either force or displacement control with improved input kinematic following, has been developed to meet these requirements. This study investigated the wear of a fixed bearing total knee replacement using this electromechanically driven fully independent knee simulator, and compared it to previous data from a predominantly pneumatically controlled simulator in which each station was not fully independently controlled. In addition, the kinematic performance and the repeatability of the simulators have been investigated and compared to the international standard requirements. The wear rates from the electromechanical and pneumatic knee simulators were not significantly different, with wear rates of 2.6 ± 0.9 and 2.7 ± 0.9 [mm3/MC] (mean ± 95% CI, p=0.99) and 5.4 ± 1.4 and 6.7 ± 1.5 [mm3/MC] (mean ± 95% CI, p=0.54) from the electromechanical and pneumatic simulators, under intermediate levels (maximum 5 mm) and high levels (maximum 10 mm) of AP displacements respectively. However, the output kinematic profiles of the control system, which drives the motion of the simulator followed the input kinematic profiles more closely on the electromechanical simulator than the pneumatic simulator. In addition, the electromechanical simulator was capable of following kinematic and loading input cycles within the tolerances of the international standard requirements (ISO 14243-3, 2014). The new generation electromechanical knee simulator with fully independent control has the potential to be used for a much wider range of kinematic conditions, including high-flexion and other severe conditions, due to its improved capability and performance in comparison to the previously used pneumatic controlled simulators. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/131/
 
Title Influence of conformity on the wear of total knee replacement: An experimental study - dataset. University of Leeds. 
Description Wear of total knee replacement continues to be a significant factor influencing the clinical longevity of implants. The aim of this study was to investigate the effect of insert conformity on the wear performance of a fixed bearing total knee replacement through experimental simulation. Two geometries of insert were studied under standard gait conditions. This dataset contains the images and wear data relating to the study understanding conformity influence on wear of a fixed bearing total knee replacement. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/id/eprint/422
 
Title PEEK CFR-PEEK pin plate study dataset 
Description Pin on plate studies to understand the influence of contact pressure, cross shear and counterface were undertaken with surface analysis measured prior to test and at completion. Mean wear factors for each condition were calculated at the completion of the study. This dataset includes the mean wear factor for each condition and the surface roughness measurements. 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/92/
 
Title PEEK and CFR-PEEK knee wear dataset 
Description This study investigated the wear performance of PEEK and CFR-PEEK in a low conformity total knee replacement configuration. Custom-made flat inserts were tested against cobalt-chromium femoral bearings in a knee wear simulation for a period of three million cycles. Wear was assessed gravimetrically at intervals throughout the study. This dataset presents the input profile for the knee wear simulator, the experimental wear data and associated figures relating to the paper 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact None 
URL http://archive.researchdata.leeds.ac.uk/137/
 
Title wear simulation model artificial hip 
Description wear simulation model artificial hip 
Type Of Material Computer model/algorithm 
Year Produced 2010 
Provided To Others? Yes  
Impact applied in industry contract research 
 
Title wear simulation model artificial knee 
Description wear simulation model artificial knee 
Type Of Material Computer model/algorithm 
Year Produced 2012 
Provided To Others? Yes  
Impact used in industry contract research 
 
Description AO Foundation 
Organisation AO Foundation
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Collaboration in tissue modelling for musculoskeletal applications
Collaborator Contribution Collaboration in tissue modelling for musculoskeletal applications
Impact The collaboration has led to CASE-type sponsorship of a PhD studentship at Newcastle.
Start Year 2017
 
Description Aterius oriented polymer stents 
Organisation Arterius Limited
Country United Kingdom 
Sector Private 
PI Contribution precision small scale die drawing of bioresorbable polymers to make oriented tubes, used to laser cut stents. Shared IP with Arterius
Collaborator Contribution Original approach to us from Arterius, IP (shared), for use of our oriented polymer routes.
Impact the only British drug eluting, resorbable stent - currently close to commercialisation, in trials. Combination of engineering sciences and pharmaceutical science.
Start Year 2009
 
Description Biocomposites Ltd 
Organisation Biocomposites
Country United Kingdom 
Sector Private 
PI Contribution Calcium Phosphate Bone Void Filler - A Pin-on-Plate Study; Calcium Sulphate Bone Void Filler Comparison - A Pin-on-Plate Study
Collaborator Contribution participate in research and publication
Impact Publication
Start Year 2014
 
Description Bradford Science Bridges China 
Organisation University of Bradford
Country United Kingdom 
Sector Academic/University 
PI Contribution Contributed to workshops and conferences
Collaborator Contribution Project is run by Bradford
Impact None as yet
Start Year 2015
 
Description Bradford Science Bridges China (TP and MSR collaborative visit to China) 
Organisation Sichuan University
Country China 
Sector Academic/University 
PI Contribution Two PDRAs working on MeDe Innovation projects attended a workshop in Chengdu where they developed two collaborative projects. We are providing materials manufactured in our laboratories for subsequent evaluation in China.
Collaborator Contribution The Chinese partners will make modifications to and/or undertake testing e.g. antimicrobial properties in their laboratories to increase knowledge of structure-property relationships in innovative devices.
Impact Multi-disciplinary with materials and life sciences applied to medicine and dentistry
Start Year 2015
 
Description Collaboration on Coatings 
Organisation Biomet, Inc
Country United States 
Sector Private 
PI Contribution Studentship
Collaborator Contribution support towards stipend and consumable of a PhD student
Impact Shared results. Conference papers/presentations and papers
Start Year 2015
 
Description Corin 
Organisation Corin Group PLC
Country United Kingdom 
Sector Private 
PI Contribution research
Collaborator Contribution funds time materials
Impact multidisciplinary engineering medicine
Start Year 2016
 
Description Credentis 
Organisation Credentis
Country Switzerland 
Sector Private 
PI Contribution Use of Self assembling peptide(SAP) technology for hard tissue engineering (dental applications)
Collaborator Contribution materilas
Impact Ip piublications
Start Year 2014
 
Description DePuy 
Organisation Depuy International
Country United Kingdom 
Sector Private 
PI Contribution Thirty-three projects.
Collaborator Contribution funds , materilas staff
Impact publications
Start Year 2013
 
Description DePuy partnership 2016 
Organisation Depuy International
Country United Kingdom 
Sector Private 
PI Contribution Research supply
Collaborator Contribution Research funding cash, materials and in kind
Impact publications IP multidisciplinary, engineering medicine biology
Start Year 2016
 
Description DePuy partnership 2017 
Organisation Depuy International
Country United Kingdom 
Sector Private 
PI Contribution Research supply
Collaborator Contribution Funding, materials , know how, staff time
Impact publications multidisciplinary engineering biological sciences, medicine
Start Year 2017
 
Description Depuy International Ltd 
Organisation Depuy International
Country United Kingdom 
Sector Private 
Start Year 2004
 
Description Depuy Kennedy 16-17 
Organisation Depuy International
Country United Kingdom 
Sector Private 
PI Contribution Knowledge advice
Collaborator Contribution knowledge expertise
Impact multidiciplines engineering medicine
Start Year 2016
 
Description Depuy Nutter 16-17 
Organisation DePuy Synthes
Country United States 
Sector Private 
PI Contribution Research , knowledge advice
Collaborator Contribution advice , knowledge
Impact knowledge advice multidisciplinary engineering biology medicine
Start Year 2016
 
Description Depuy Synthes 
Organisation Depuy International
Country United Kingdom 
Sector Private 
PI Contribution Collaboration in the area of additive manufacture of orthopaedic implants
Collaborator Contribution Collaboration in the area of additive manufacture of orthopaedic implants
Impact Collaboration has led to CASE-type studentship support for two research students
Start Year 2017
 
Description Edwards Powell 2016-17 
Organisation Edwards Lifesciences Corporation
Country United States 
Sector Private 
PI Contribution knowledge advice
Collaborator Contribution advice expertise
Impact multidisciplinary engineering , mediicne
Start Year 2016
 
Description GTS 
Organisation Glass Technology Services
Country United Kingdom 
Sector Private 
PI Contribution 3d printing of bioceramic powders.
Collaborator Contribution Provision of raw materials
Impact Has also led to support for a CASE studentship
Start Year 2013
 
Description Innovate Orthopaedics - soft tissue and bone fixations 
Organisation Innovate Orthopaedics Ltd
Country United Kingdom 
Sector Private 
PI Contribution Solid phase orientation of polymers for a range of soft tissue and bone fixation shape memory devices
Collaborator Contribution technical and market knowledge for fixations, and clinician connections
Impact new 3 year EPSRC HIP grant being announced, March 2018
Start Year 2017
 
Description JRI 
Organisation JRI Orthapaedics
Country United Kingdom 
Sector Private 
PI Contribution Design and manufacture of medical devices
Collaborator Contribution Design and manufacture of medical devices
Impact Has led to translational award funded by Arthritis Research UK
Start Year 2013
 
Description JRI BRNDOG 
Organisation JRI Orthapaedics
Country United Kingdom 
Sector Private 
PI Contribution research and IP
Collaborator Contribution Commercialisation route an droad mapping
Impact further funding - road mapping and progress to commercialisation
Start Year 2015
 
Description Joao Fernandes placement (from 3Bs University of Minho, Portugal) 
Organisation University of Minho
Department 3B’s Research Group (Biomaterials, Biodegradables and Biomimetics)
Country Portugal 
Sector Academic/University 
PI Contribution 6 month PhD student placement on MeDe associated project with Hatton, Miller and Crawford as Sheffield research supervisors.
Collaborator Contribution Provision of PhD student and glasses prepared in the 3Bs group in Portugal.
Impact Papers submitted, to be updated
Start Year 2015
 
Description Joint International Laboratory for Polymer Micro Processing 
Organisation Sichuan University
Country China 
Sector Academic/University 
PI Contribution Establishment of a micro moulding facility in Sichuan, to mirror the (more extensive) facilities in Bradford, to develop further our collaborative research. Joint IP for conducting polymer products.
Collaborator Contribution Materials engineering expertise, including polymer nano composite products, especially for electrically conducting products. Joint IP for conducting polymer products.
Impact Joint publications. Joint IP
Start Year 2010
 
Description Joint International Laboratory for Soft Matter Technologies 
Organisation Beijing University of Technology
Department College of Environmental and Energy Engineering
Country China 
Sector Academic/University 
PI Contribution Hosting Researcher Exchanges leading to joint publications; advisory role with respect to development of particular technologies
Collaborator Contribution sending researchers to our laboratory, leading to joint publications; Support (from Prof Zhang Liqun) for meetings with the Ministry of Science & Technology in Beijing
Impact joint publications
Start Year 2016
 
Description Joint Laboratory for Polymer Process Physics 
Organisation Changchun Institute of Applied Chemistry
Country China 
Sector Academic/University 
PI Contribution Royal Society Newton award, following Science Bridges China researcher exchanges (two way)
Collaborator Contribution High quality x-ray analysis of oriented polymers
Impact Journal papers (Macromolecules)
Start Year 2015
 
Description LMBRU LTHT 
Organisation Leeds Teaching Hospitals NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution patient specific and population based simulation an d modelling publications and outputs
Collaborator Contribution clinical imaging patient data retrieval bank patient participation
Impact publications simulation methods new standards joint grant applications
Start Year 2015
 
Description LTHT 
Organisation Leeds Teaching Hospitals NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution research
Collaborator Contribution facilities, materials implants data
Impact engineering medicine
Start Year 2016
 
Description Mathys Medical 
Organisation Mathys
Country Switzerland 
Sector Private 
PI Contribution Four projects including: Evaluation of potential ceramic matrix hips Ceramic matrix composite hip Wear of Experimental Ceramics in Total Hip Replacement - A Hip Joint Simulator Study (Mathys IV) Wear of Experimental Ceramics in Total Hip Replacement - A Hip Joint Simulator Study (Mathys V)
Collaborator Contribution materials , research methods , analysis
Impact papres
Start Year 2013
 
Description Medical Technologies Innovation and Knowledge Centre 
Organisation University of Leeds
Country United Kingdom 
Sector Academic/University 
PI Contribution Academic partner in the network
Collaborator Contribution Leeds University leads the programme
Impact None yet
Start Year 2016
 
Description NAMSA 
Organisation North American Science Associates Inc
Country United States 
Sector Private 
PI Contribution In vivo testing of dCell bone to detremine osseointegration and biocompatibility
Collaborator Contribution undertaking research work
Impact pubication
Start Year 2015
 
Description NHSBT 
Organisation NHS Blood and Transplant (NHSBT)
Department National Blood Service
Country United Kingdom 
Sector Public 
PI Contribution Research
Collaborator Contribution funding, materials and time
Impact publications multidisciplinary engineering biology
Start Year 2016
 
Description National Blood Service 
Organisation NHS Blood and Transplant (NHSBT)
Department National Blood Service
Country United Kingdom 
Sector Public 
Start Year 2003
 
Description Neotherix 
Organisation Neotherix Ltd
Country United Kingdom 
Sector Private 
PI Contribution Repair of oral and peridontal defects using regenerative and antibacterial strategies delivered by a novel tissue scaffold vehicle Polymeric scaffolds functionalised for periodontal repair
Collaborator Contribution materials
Impact multidisciplinary
Start Year 2015
 
Description Nuvasive 
Organisation Nuvasive
Country United States 
Sector Private 
PI Contribution Cellular Characterisation of Osteocel Plus
Collaborator Contribution materials
Impact multidisciplinary engineering medicne
Start Year 2013
 
Description Re-distributed Manufacturing in Healthcare Network 
Organisation University of the West of England
Department Department of Geography and Environmental Management
Country United Kingdom 
Sector Academic/University 
PI Contribution Member of the executive group of the network, and contributed to events and workshops
Collaborator Contribution Network was led by UWE, with input also from Nottingham, Brunel and Cambidge Universities
Impact No outputs to date. Engineering and healthcare disciplines
Start Year 2015
 
Description Sabic programme on micro needle manufacture 
Organisation Saudi Basic Industries Corporation
Country Saudi Arabia 
Sector Private 
PI Contribution research skills and facilities
Collaborator Contribution commercial opportunities and materials tailoring
Impact confidential to company
Start Year 2015
 
Description Simpleware 
Organisation Simpleware Ltd
Country United Kingdom 
Sector Private 
PI Contribution Development of finite element simulation tools to capture patient variation for the analysis of orthopaedic devices across a patient cohort
Collaborator Contribution software
Impact papers
Start Year 2014
 
Description Simsol2016 
Organisation Simulation Solutions
Country United Kingdom 
Sector Private 
PI Contribution Research
Collaborator Contribution equipment , staff time, expertise
Impact multidisciplinary engineering medicine
Start Year 2016
 
Description Simulation Solutions 
Organisation Simulation Solutions
Country United Kingdom 
Sector Private 
PI Contribution 10 projects in collaboration with Simulation Solutions: High flex knee simulator Natural knee simulator Natural hip simulator Natural spine simulator Natural joint friction simulator knee joint simulator SOP for hip simulator SOP for knee simulator Natural Knee Simulation System Electro mechanical hip simulator method SOP and training
Collaborator Contribution equipment development
Impact publications
Start Year 2014
 
Description Sinopec solid phase orientation project 
Organisation Sinopec Group
Country China 
Sector Private 
PI Contribution research skills and facilities for solid phase orientation processing of polymers
Collaborator Contribution materials manipulation and supply
Impact confidential to company
Start Year 2013
 
Description Smith & Nephew programmes 
Organisation Smith and Nephew
Country United Kingdom 
Sector Private 
PI Contribution solid phase processing of polymers and development of shape memory materials and products for tissue fixations. Joint IP on these materials and products.
Collaborator Contribution Development of shape memory materials and products for tissue fixations. Joint IP on these materials and products. Clinical challenges and assistance.
Impact extensive knowledge on shape memory materials for potential products in fixations. Combination of physics, mechanical engineering, biomedical engineering, biomaterials, medical technology.
 
Description Supply of GMP Collagen 
Organisation Collagen Solutions
Country United Kingdom 
Sector Private 
PI Contribution Information of collagen materials manufacturing
Collaborator Contribution FoC supply of commercial grade GMP collagen
Impact Manufacture of collagen fibres and gels
Start Year 2014
 
Description The General Infirmary at Leeds 
Organisation Leeds General Infirmary
Country United Kingdom 
Sector Hospitals 
Start Year 2004
 
Description Tissue 
Organisation Tissue Regenix Ltd
Country United Kingdom 
Sector Private 
PI Contribution Research
Collaborator Contribution materials
Impact multidisciplinary engineering biology
Start Year 2016
 
Description Tissue Regenix Ltd 
Organisation Tissue Regenix Ltd
Country United Kingdom 
Sector Private 
PI Contribution research
Collaborator Contribution materials Ip
Impact papers
Start Year 2014
 
Description Vascutec 
Organisation Vascutek Ltd
Country United Kingdom 
Sector Private 
PI Contribution Heart valve conduit
Start Year 2010
 
Description Visiting PhD studentship from Politecnico di Torino to MeDe Innovation at Sheffield (Silvia Caddeo) 
Organisation Polytechnic University of Turin
Department Department of Mechanical and Aerospace Engineering (DIMEAS)
Country Italy 
Sector Academic/University 
PI Contribution Silvia Cadeo has manufactured a series of porous scaffolds that mimic healthy and osteoporotic bone in terms of porosity and surface area:volume ratio. Working with the Sheffield lead (Hatton) and other academics associated with MeDe Innovation, Sylvia has demonstrated that bone marrow stromal cells respond differently to the two scaffold systems, and that these differences do not appear to be related solely to changes in mass transfer and related phenomena. Towards this work, the MeDe team at Sheffield have provided expertise in bone cell culture and bioassays.
Collaborator Contribution The partners have provided the PhD student (Silvia Caddeo) for six months and two types of fully characterised porous scaffolds manufactured in Italy.
Impact Abstract submitted for presentation at TERMIS-EU 2016 in Uppsala and publication in European Cells and Materials. Full papers are in preparation.
Start Year 2015
 
Description invibio 2016 
Organisation Invibio
Country United Kingdom 
Sector Private 
PI Contribution research
Collaborator Contribution funds, time, materials
Impact multidiciplinary
Start Year 2016
 
Title COMPOSITE BONE IMPLANTS 
Description The invention provides natural multi-composite bone implants such as bone-connective tissue-bone and osteochondral implants for the replacement and/or repair of, for example and in particular a damaged or defective bone-meniscus-bone joint or a bone-patella tendon-bone joint or osteochondral lesions, methods of preparing the composites and uses thereof. The invention also provides natural or native composite bone-connective tissue- bone and osteochondral matrices or scaffolds that are substantially decellularised for subsequent transplantation/implantation. 
IP Reference WO2014037713 
Protection Patent application published
Year Protection Granted 2014
Licensed No
Impact Proof of concept phase in large animal model completed for bone-tendon-bone, discussions ongoing with a company on development re licensing
 
Title Implant 
Description A method of manufacture of an at least partially bioresorbable implant, the method comprising the steps of: providing an at least partially bioresorbable precursor containing a polymeric material; and forming an implant by forging the precursor. An at least partially bioresorbable forged implant containing a polymeric material. 
IP Reference US20150133934 
Protection Patent application published
Year Protection Granted 2015
Licensed No
Impact Publication of five peer-reviewed journal papers.
 
Title Improvements relating to bone anchors patent application number 1511646.0 (July 2015) 
Description Improvements relating to bone anchors 
IP Reference GB1511646.0 
Protection Patent application published
Year Protection Granted 2015
Licensed Commercial In Confidence
Impact commercialization through licensing to third parties
 
Title METHOD OF PRODUCING A TUBE FOR USE IN THE FORMATION OF A STENT, AND SUCH TUBE 
Description Bioresorbable polymeric tubes suitable for use in a stent have been produced by a using a die drawing technique, comprising: - deforming an orientable, thermoplastic polymer tubing (4) in the solid phase by drawing it over a mandrel (1) and/or through a die (3), where the mandrel (1) has a lead end and an exit end and the die (3) has an entry side and an exit side, wherein a drawing mechanism applies a drawing tension to the tubing (4) from the exit end of the mandrel (1) and/or the exit side of the die (3), said tension being insufficient to cause tensile failure of the tubing but sufficient to deform the tubing, thereby drawing the tubing over the mandrel (1) and/or through the die (3) in the solid phase to induce uniaxial or biaxial orientation of the polymer; and - collecting the deformed tubing from the exit end of the mandrel (1) and/or the exit side of the die (3). 
IP Reference WO2014045068 
Protection Patent granted
Year Protection Granted 2014
Licensed Commercial In Confidence
Impact this is the only UK-based route to bioresorbable polymer stents, from a company set up in the University of Bradford incubator.
 
Title PRINTING APPARATUS AND METHOD 
Description A printing apparatus and method. The printing apparatus is for impinging liquids from at least two liquid sources. The apparatus comprises a first jet actuator configured to dispense a first liquid from a first liquid source and a second jet actuator configured to dispense a second liquid from a second liquid source. The apparatus further comprises an adjustment element configured to adjust a trajectory of at least the first liquid dispensed from the first jet actuator such that the first liquid impinges the second liquid dispensed from the second jet actuator. 
IP Reference WO2019008373 
Protection Patent application published
Year Protection Granted 2019
Licensed No
Impact None to date.
 
Title Porous Material 
Description A porous material comprising a substantially continuous matrix comprising an at least-partially-cross-linked water-soluble polymer with pores therein. The present invention relates to a porous material and articles or products comprising the porous material. The invention also relates to methods of manufacture and uses of the porous material and articles or products comprising the porous material. Porous materials are useful in a wide range of applications, including medical and non-medical applications. 
IP Reference GB1717112.5 
Protection Patent application published
Year Protection Granted 2017
Licensed No
Impact Obtaining several grants such as EPSRC IAA, ARUK and IKC.
 
Title Additive manufacture of personalised implants 
Description Manufacture of personalised musculoskeletal implants in titanium alloy using EBM and SLM technology through KTP with DePuy-Synthes 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Initial development
Year Development Stage Completed 2017
Development Status Under active development/distribution
Impact New knowledge on design and QA of metal additive manuafctured parts 
 
Title Arthroscopic cartilage repair process and material 
Description In vivo material deposition for cartilage defect repair - being refined to give best combination of materials and deposition effectiveness. 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Initial development
Year Development Stage Completed 2016
Development Status Under active development/distribution
Impact None yet. 
 
Title Biphase osteochondral plug 
Description Osteochondral plug, currently being evaluated in a large animal study. 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Refinement. Non-clinical
Year Development Stage Completed 2016
Development Status Under active development/distribution
Impact None yet. 
 
Title Cell-infused scaffolds for musculoskeletal repair 
Description Processing techniques which can co-process cells and load bearing materials to create autologous cell infused scaffolds for musculoskeletal repair. 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Initial development
Year Development Stage Completed 2016
Development Status Under active development/distribution
Impact None yet. 
 
Title High Throughput Bioprinting Technologies 
Description New printheads for high throughput cell printing - potential for use in creating micro-tissues for therapeutic use. 
Type Support Tool - For Medical Intervention
Current Stage Of Development Initial development
Year Development Stage Completed 2016
Development Status Under active development/distribution
Impact Could also be used for drug screening or disease models 
 
Title ISO accredited simulation test laboratory 
Description ISO accredited simulation test laboratory for pre clinical testing and trials widely used by customers around globe 
Type Support Tool - For Medical Intervention
Current Stage Of Development Wide-scale adoption
Year Development Stage Completed 2013
Development Status Under active development/distribution
Impact uptake by wide range of companies 
 
Title Minimally Invasive Delivery of Osteospheres 
Description Prototype Device for Minimally Invasive Delivery of Osteospheres for the Treatment of Osteoporosis 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Refinement. Non-clinical
Year Development Stage Completed 2014
Development Status Actively seeking support
Impact still under development 
 
Title Mobile Phone Based Diagnostic Systems 
Description Point of care diagnostic systems developed for use with mobile phone cameras and analysis 
Type Diagnostic Tool - Imaging
Current Stage Of Development Initial development
Year Development Stage Completed 2016
Development Status Under active development/distribution
Impact New chip design for lab-on-a-chip systems 
 
Title acellular bone 
Description under development and in in vivo trials 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Refinement. Non-clinical
Year Development Stage Completed 2014
Development Status Under active development/distribution
Impact under development and in animal trials 
 
Title acellular bone cartilage osteochondral graft 
Description under development 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Initial development
Year Development Stage Completed 2014
Development Status Under active development/distribution
Impact under developemnt 
 
Title acellular bone cartilage osteochondral graft 
Description under development NHSBT 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Initial development
Year Development Stage Completed 2015
Development Status Under active development/distribution
Impact under development 
 
Title acellular bone patellar bone graft 
Description under development by NHSBT 
Type Therapeutic Intervention - Surgery
Current Stage Of Development Refinement. Non-clinical
Year Development Stage Completed 2014
Development Status Under active development/distribution
Impact under development by NHSBT 
 
Title acellular dcell dermis 
Description commercialised by Tissue regenix from 2014 
Type Therapeutic Intervention - Medical Devices
Year Development Stage Completed 2014
Development Status Under active development/distribution
Impact sold and distributed in USA 
 
Title acellular dermis 
Description supplied as clinical product by NHSBT 
Type Therapeutic Intervention - Surgery
Current Stage Of Development Small-scale adoption
Year Development Stage Completed 2014
Development Status Under active development/distribution
Impact supplied by NHSBT, improved wound healing in chronic leg ulcers 
 
Title all polymer knee 
Description collaborative development with Invibio 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Initial development
Year Development Stage Completed 2015
Development Status Under active development/distribution
Impact collaborative development with Invibio 
 
Title bioresorbable polymer arterial stent 
Description Arterius Ltd have previously secured InnovateUK funding with us, and have most recently undertaken in-animal trials which show a very successful performance of the stents compared with market leading metallic stents. 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Initial development
Year Development Stage Completed 2017
Development Status Under active development/distribution
Impact die drawing technology transferred from the University to Arterius who now have a precision processing facility in a clean room in their company. 
URL http://arterius.co.uk
 
Title dcell ligament 
Description Under commercial development by tissue Regenix, progressing to CE mark and product launch 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Refinement. Non-clinical
Year Development Stage Completed 2014
Development Status Under active development/distribution
Clinical Trial? Yes
Impact under commercial development by Tissue Regenix in clinical trial started 2015 proceeding to Ce mark and product launch 2017 
URL https://clinicaltrials.gov/show/NCT02540811
 
Title dcell meniscus 
Description Developed by tissue Regenix In clinical trial started 2015 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Late clinical evaluation
Year Development Stage Completed 2014
Development Status Under active development/distribution
Clinical Trial? Yes
Impact first in man clinical trial started 2015 
URL https://clinicaltrials.gov/show/NCT02270905
 
Title ankle joint simulator 
Description ankle joint simulator 
Type Of Technology Physical Model/Kit 
Year Produced 2015 
Impact support product development 
 
Title hip joint simulator 
Description hip joint simulator 
Type Of Technology Physical Model/Kit 
Year Produced 2012 
Impact commercial product Simulation solutions 
 
Title knee joint simulator 
Description knee joint simulator 
Type Of Technology Physical Model/Kit 
Year Produced 2013 
Impact Commercial product simulation solutions 
 
Title patellar simulator 
Description patellar femoral joint simulator 
Type Of Technology Physical Model/Kit 
Year Produced 2009 
Impact Support for new product development 
 
Company Name Tissue Regenix 
Description Developemnt and manufacture of Regenerative Biological Scaffolds for tissue repair in vascular, cardiovascular and musculoskeletal systems 
Year Established 2007 
Impact aim listed d raised £0m investment value £150m 4 clinical products
 
Description 10th World Biomaterials Congress (WBC) (Montreal, Canada) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Urasha Patel had a poster about her PhD work under the title of ''Calcium/strontium substituted phosphate based glasses for orthopaedic applications''.
Year(s) Of Engagement Activity 2016
URL http://wbc2016.org/index.php/wbc-2016
 
Description 10th World Biomaterials Congress (WBC) (Montreal, Canada) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Colin Scotchford had a poster about Integrated Multimodal Analysis Platform for Stem Cell Chondrogenic Differentiation.
Year(s) Of Engagement Activity 2016
URL http://www.wbc2016.org/
 
Description 10th World Biomaterials Congress (WBC) (Montreal, Canada) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Andy Parsons had a poster about integrated molecular design of melt-processable Bioresorbable Engineering Nanocomposites for Healthcare (BENcH).
Year(s) Of Engagement Activity 2016
URL http://wbc2016.org/index.php/wbc-2016
 
Description 15th Annual Conference United Kingdom Society of Biomaterials (UKSB) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Dhanak Gupta, Ifty Ahmed, Zakir Hossain, David Grant and Virginie Sottile. Behaviour and osteogenic differentiation of human mesenchymal stem cells on 2D and 3D culture environments
Year(s) Of Engagement Activity 2016
URL https://sites.google.com/a/my.westminster.ac.uk/uksb2016/
 
Description 15th Annual Conference United Kingdom Society of Biomaterials (UKSB) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Caitriona McCarron, Virginie Sottile and Ifty Ahmed. Resorbable Invert Phosphate Glasses for Orthopaedic Applications
Year(s) Of Engagement Activity 2016
URL https://sites.google.com/a/my.westminster.ac.uk/uksb2016/
 
Description 15th Annual Conference United Kingdom Society of Biomaterials (UKSB) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Ifty Ahmed, Uresha Patel, Zakir Hossain, Virginie Sottile, David Grant and Brigitte Scammell. Novel Microstructural Features in Resorbable Phosphate-Based Glass Microspheres
Year(s) Of Engagement Activity 2016
URL https://sites.google.com/a/my.westminster.ac.uk/uksb2016/
 
Description 16th Annual Conference United Kingdom Society of Biomaterials (UKSB) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Over 100 delegates from the UK Society of Biomaterials, industry representatives and academics were present for the annual conference at Loughborough University. Katherine Pitrolino presented my work to all that attended. Her work was well received and I won first prize for the best oral presentation.
Year(s) Of Engagement Activity 2017
URL http://www.lboro.ac.uk/departments/chemistry/news-events/events/2017/uk-society-for-biomaterials--16...
 
Description 16th International Conference on Deformation, Yield and Fracture of Polymers (Kerkrade, Netherlands) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Mike ward presented his PhD work about mechanical response and structure evolution of degrading medical polylactides for resorbable medical implants.
Year(s) Of Engagement Activity 2015
URL http://www.dyfp2015.tue.nl/
 
Description 18th EFORT Vienna Congress (Vienna) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Wear analysis of explanted conventional metal back polyethylene glenoid liners
Year(s) Of Engagement Activity 2017
URL https://www.efort.org/vienna2017/
 
Description 2016 China-UK Researcher Links Workshop on Healthcare Technologies, Sichuan Province, Chengdu, China 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact During the workshop, 50 scholars from both nations presented their technical reports or wall exhibitions, and sorted out, by seriously discussing and combing the potential innovative points of future China-UK cooperation, over 20 specific cooperative research ideas, covering some cutting-edge interdisciplinary research areas like bio-medical technologies, tissue engineering restoration materials, artificial skin materials, drug sustained-release materials and medical electrodes. The attended representatives also visited the SCU's State Key Laboratory of Polymer Materials Engineering and International Cooperation Research Center for Biomaterials, as well as Chengdu OCI Medical Devices Co., Ltd, thus having an insight into the SCU's 120-year historical and cultural connotations and technological innovation spirit, as well as the development status and prospect of biomedical materials in Sichuan Province. This successful workshop has set up a communication platform for Chinese and British young scholars and laid a solid foundation for further communication and cooperation in the future.
Year(s) Of Engagement Activity 2016
URL http://www.scu.edu.cn/en/news/webinfo/2016/12/1478149598054427.htm
 
Description 20th International Conference on Composite Materials (Copenhagen, Denmark) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Andy Parsons had a presentation about Developing Multifilament Drawing Facilities for Phosphate Glasses
Year(s) Of Engagement Activity 2015
URL http://www.iccm20.org/
 
Description 20th International Conference on Composite Materials (Copenhagen, Denmark) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Menghao Chen presented his PhD work about developing an in-situ polymerisation process for biocomposite manufacturing.
Year(s) Of Engagement Activity 2015
URL http://www.iccm20.org/
 
Description 29th EUROPEAN SOCIETY FOR BIOMATERIALS 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Michal Zurawski had a poster presentation about his research on the investigation into bacterial biofilm formation on metal orthopaedic scaffolds.
Year(s) Of Engagement Activity 2018
URL http://www.esbiomaterials.eu/
 
Description 29th EUROPEAN SOCIETY FOR BIOMATERIALS 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Kathryn Thomas presented a poster about her research on sacrificial phosphate based glass coatings for in vivo biofilm prevention.
Year(s) Of Engagement Activity 2018
URL http://www.esb2018maastricht.org/
 
Description 30th Annual Conference of the Polymer processing society (Cleveland, Ohio) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Gabriel Choong gave a presentation about Rheological Techniques for Determining Degradation of Polylactic Acid in Bioresorbable Medical Polymer Systems.
Year(s) Of Engagement Activity 2014
URL http://www.pps30.com/
 
Description 30th Annual Meeting of the Wound Healing Society 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation by Dr. Tronci on Photoactive Type I (atelo) collagen as Building Blocks of Advanced Wound Dressings
Year(s) Of Engagement Activity 2018
 
Description 32nd international conference of the Polymer Processing Society (Lyon, France) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Magdalena M. Tomczynska presented her PhD work about the effect of particle morphology and dispersants on processing and properties of PLA-HA nanocomposites
Year(s) Of Engagement Activity 2016
URL https://pps-32.sciencesconf.org/
 
Description 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'16) (Florida, USA) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Investigation of changes in the electrical properties of novel knitted conductive textiles during cyclic loading
Year(s) Of Engagement Activity 2016
URL http://embc.embs.org/2016/
 
Description 3D MedNet Bioprinting article 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact In this interview, Kenny Dalgarno, Newcastle University (UK), discusses his work with Arthritis Research UK (Chesterfield, UK), development of a revolutionary method of 3Dbioprinting and the road ahead to commercializing 3D printing and bioprinting.
Year(s) Of Engagement Activity 2016
 
Description 3D-bioprinting: The next step for additive manufacture in orthopaedics 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Online article profiling Kenny Dalgarno and his work on 3D printing of cells and how it's helping to promote tissue regeneration
Year(s) Of Engagement Activity 2018
URL http://www.opnews.com/2018/05/3d-bioprinting-the-next-step-for-additive-manufacture-in-orthopaedics/...
 
Description 3rd International Conference on Bio-based Polymers and Composites (BiPoCo) (Szeged, Hungary) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Michael Ward presented his PhD work about the influence of process conditions on the structure and properties of melt processed poly (lactic acid) nanohydroxyapatite composites
Year(s) Of Engagement Activity 2016
URL http://www.bipoco2016.hu/
 
Description 5th International Conference of Bionic Engineering (Ningbo, China) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Andy Parsons gave a presention about melt-processed PLA/HA platelet nanoparticle composites produced using tailored dispersants.
Year(s) Of Engagement Activity 2016
URL http://www.icbe2016-unnc.org/
 
Description Arthritis Research Christmas Open Morning Discussion 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Supporters
Results and Impact Presentation at the Arthritis Research Christmas Open Morning Discussion on "3D Printing".
Year(s) Of Engagement Activity 2018
 
Description Article in China Daily, 9 Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact China Daily article in Beijing, after the Award Ceremony for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.chinadaily.com.cn/a/201801/09/WS5a53fa36a31008cf16da5d10.html
 
Description Article: Regen Med Nears the Market - GEN 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Supporters
Results and Impact Article published by Genetic Engineering and Biotechnology news about the IKC and Regener8

Increased memberships to Regener8
Year(s) Of Engagement Activity 2012
URL http://www.genengnews.com/gen-articles/regen-med-nears-the-market/4597/
 
Description Ask the Expert - Clinically Led Manufacture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Four separate presentations given by:
- Prof Nikos Donos, Head of the Clinical Oral Research Center at the Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London (QMUL) in collaboration with SJ Russell.
- SJ Russell (Leeds)
- P Giannoudis (Leeds)
- M. Mehr (Geistlich Pharma AG)
Year(s) Of Engagement Activity 2018
URL http://mede-innovation.ac.uk/event/mede-innovation-ask-expert-oct-18/
 
Description Ask the Expert: Biomaterials and manufacturing from a clinical perspective 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact This event will give an overview of novel biomaterials from the perspective of an Orthopaedic surgeon and a Maxillofacial prosthetist. As biomaterials are expanding from bio inert prosthetics to next generation bioactive materials, the interaction of implantable materials with living tissue is transforming the medical field leading to less invasive and more effective treatments. The eventual commercialisation of implantable devices is governed by clinical demand and proven efficacy.

Repairs to hard tissue often require metallic pins, screws and plates to be surgically implanted. These fixation devices can then require further surgery at a later stage to remove them. This carries inherent risks to the patient, so it is attractive to instead use fully resorbable devices that will gradually transfer load to the healing tissue over time. One of the main hurdles to achieving this is the different degradation rates that can occur with resorbable devices, which can often lead to premature loss of mechanical properties, preventing proper integration and tissue remodelling.

This workshop will give an overview of the current research and offer attendees the opportunity to discuss the technologies with engineers, scientists and clinicians who work with it on a day-to-day basis.
Year(s) Of Engagement Activity 2018
URL http://mede-innovation.ac.uk/event/mede-innovation-ask-expert-biomaterials/
 
Description BORS Annual Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The BOARS conferences are designed for the communication of work in progress and as such are particularly suitable for clinician/scientists who would like feedback on their research.
Year(s) Of Engagement Activity 2015
 
Description British Council Newton Researcher Links Workshop for Early Career Researchers 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact 13 UK-China Researcher Exchanges (funded separately from the Workshop) are being set up to run before Sep 2017
Year(s) Of Engagement Activity 2016
URL http://www.ukchina-amri.com
 
Description British Orthopaedic Association (BOA) Annual Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Engagement of clinicians and industry
Year(s) Of Engagement Activity 2015
 
Description CCTV longer interview 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact CCTV mainstream news - my experience of the Golden Era through my research collaborations, and a celebration of the top award in China to a foreign scientist.
Year(s) Of Engagement Activity 2018
URL http://www.ukchina-amri.com
 
Description China Daily Europe article on top award in China made to Prof Phil Coates; 12 Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact China Daily article in Europe, after the Award Ceremony in Beijing for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://europe.chinadaily.com.cn/a/201801/12/WS5a57acafa3102c394518ea1e.html
 
Description Chinese International Award 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Articles in China Daily - in English - in the UK and China; and other Chinese national newspapers concerning the Award to Prof Coates of the International Science & Technology Cooperation Award, the top award in China for a foreign scientist.
Year(s) Of Engagement Activity 2018
URL http://www.ukchina-amri.com
 
Description Chracterisation and Treatment of Wounds Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact This workshop provides an opportunity for academics to meet with likeminded individuals to develop and discuss ways to address identified un-met clinical needs in the area of wound characterisation and treatment. We will discuss identified un-met clinical needs, develop new patient-focussed ideas which respond to these needs, and refine ideas into potential project opportunities which can be further supported and progressed in conjunction with the Translate team. The workshop will also provide a forum for presentations from national organisations and funders, relevant to your area of work.

Specifically, the workshop will focus on:

• Physical, non-invasive methodologies to measure and characterise the condition and status of a wound
• Techniques for treating wounds to promote new blood vessels, blood flow, or tissue regeneration
Year(s) Of Engagement Activity 2016
 
Description ECNS China article on top Chinese Award to Prof Phil Coates, 12 Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact ECNS article in Beijing, after the Award Ceremony for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.ecns.cn/business/2018/01-12/288042.shtml
 
Description EPSRC Website blog by John Fisher 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Online article profiling the Engineer's Collaborate to Innovate (C2I) Awards. The leads for three of the winning categories highlight their work - including John Fisher profiling the EPSRC Centre for Innovative Manufacturing in Medical Devices
Year(s) Of Engagement Activity 2017
URL https://epsrc.ukri.org/blog/great-research-and-innovation-have-collaboration-at-their-core/
 
Description ESB2014 talk High-Throughput Quantitative Chondrogenic Assay for Stem Cell Differentiation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Participants in your research and patient groups
Results and Impact Discussion

Future collaborations
Year(s) Of Engagement Activity 2014
URL http://esb2014.org/
 
Description Early Career Researcher 2 day residential 'Sandpit' workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact This 2 day workshop was a forum for Early Career Researchers (ECR) to discuss and share potential research opportunities with a view to pitching for £5000 (FEC) funding from MeDe Innovation to undertake the chosen projects. Projects had to be a collaboration between at least two Universities/companies.

ECR's were also given presentations on various aspects of professional development, such as grant writing and IP.

At the end of the two days, the ECR's pitched ideas to a panel of industry and academic MeDe members and 2 projects were awarded funding to progress.
Year(s) Of Engagement Activity 2016
 
Description Early Career Researcher Meeting 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact The MeDe Innovation Early Career Researchers take part in a half day meeting, with presentations from industry/academics, along with group work, followed by dinner and networking opportunities to build relationships and share potential research ideas.
Year(s) Of Engagement Activity 2017
 
Description Early Career Researcher meeting 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact The MeDe Innovation Early Career Researchers take part in a half day meeting, with presentations from industry/academics, along with group work, followed by dinner and networking opportunities to build relationships and share potential research ideas.
Year(s) Of Engagement Activity 2016
 
Description Emerging Nanomaterials for Healthcare conference (Warwick, UK) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Gabriel Choong presented about Processability and mechanical response of melt processable medical polylactides for resorbable nanocomposite implants.
Year(s) Of Engagement Activity 2014
URL http://www2.warwick.ac.uk/fac/sci/chemistry/research/davies/daviesgroup/conferences/nanomaterialscon...
 
Description Emerging Nanomaterials for Healthcare conference (Warwick, UK) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Andy Parsons presented about Bioresorbable Engineering Nanocomposites for Health-Care (BENcH).
Year(s) Of Engagement Activity 2014
URL http://www2.warwick.ac.uk/fac/sci/chemistry/research/davies/daviesgroup/conferences/nanomaterialscon...
 
Description Engineering Expo Conference 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Presentation at Engineering Expo Conference 2018 on "A Model for Academic/Business Collaboration: How MeDe Innovation is Driving Advances in the UK's Medical Devices Sector"
Year(s) Of Engagement Activity 2018
 
Description European Inventor of the Year Announcement 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Website article highlighting the nomination of Eileen Ingham and John Fisher for the EU Inventor of the Year prize in 2018.
Year(s) Of Engagement Activity 2018
URL http://medical-technologies.leeds.ac.uk/news-post/john-fisher-and-eileen-ingham-shortlisted-for-an-i...
 
Description European Society of Biomechanics Annual Congress (Lyon, France) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Achieving powered assisted motion of the trunk without an articulated exoskeleton
Year(s) Of Engagement Activity 2016
URL https://esbiomech.org/conference/index.php/congress/lyon2016/
 
Description European and UK Society of Biomaterials (Liverpool, UK ) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact RF Magnetron Sputtering of Multicomponent Ion Doped Phosphate Glasses
Year(s) Of Engagement Activity 2014
URL http://www.esb2014.org/
 
Description Event Exhibition: Healthcare Innovation Expo, ExCel London 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Europe's largest, most exciting healthcare innovation event 13th & 14th March 2013. The IKC hosted an exhibition stand at the event to connect to potential clinical partners.

Increased understanding of clinical needs. Increased engagement with clinicians.
Year(s) Of Engagement Activity 2013
URL http://www.nic.nhs.uk/Pages/ArchivedNews-4.aspx
 
Description Event Exhibition: Innovate 13, Business Design Centre, London 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Supporters
Results and Impact 4,000 people from UK and international business, Government and academia attended to do business.

Made contacts now members of the IKC community.
Year(s) Of Engagement Activity 2011,2013
URL https://www.innovateuk.org/-/innovate-uk-11th-13th-march-2013
 
Description Event delivered: The Future of Vertebroplasty, London 
Form Of Engagement Activity Scientific meeting (conference/symposium etc.)
Part Of Official Scheme? No
Type Of Presentation workshop facilitator
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Presentations on the future of vertebroplasty. A facilitated discussion with the aim of identifying and shaping future biomechanical research to improve vertebroplasty.

Test test test
Year(s) Of Engagement Activity 2013
 
Description Event delivered: The Future of Vertebroplasty, London 
Form Of Engagement Activity Scientific meeting (conference/symposium etc.)
Part Of Official Scheme? No
Type Of Presentation workshop facilitator
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Presentations on the future of vertebroplasty. A facilitated discussion with the aim of identifying and shaping future biomechanical research to improve vertebroplasty.

Test test test
Year(s) Of Engagement Activity 2013
 
Description Glass Focus 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Presentation at Glass Focus 2016, "Future Manufacturing", Edinburgh, 12th May, 2016.
Year(s) Of Engagement Activity 2016
 
Description Global Spine Congress 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact D. McNally , A. Parish1, S. Johnson, G., Quantifying the quality of graft remodeling in cervical fusion
Year(s) Of Engagement Activity 2017
URL http://www.gsc2017.org/
 
Description Global Spine Congress (Milan) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Quantifying the quality of bone graft remodelling in cervical fusion
Year(s) Of Engagement Activity 2017
URL http://gsc2017.org/
 
Description Guest Lecture #1 - Professor Kenny Dalgarno at University of Leeds 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact The MeDe Innovation Guest Lecture Series is a programme of lectures led by its esteemed academic leadership in the field of innovative medical device manufacturing throughout 2015.

During the visit to a MeDe Innovation academic centre, the invited guest will present their research in a free to attend, open lecture. There are also other opportunities for the research community to engage in activities; such as ECR meetings, lab tours and the chance to present.

Attendees are invited from across the medical device manufacturing (Class III) sector.

Through the MeDe Innovation Guest Lecture Series, the research community can learn, meet, network, share experience, and build stronger cross-centre relationships.
- See more at: http://mede-innovation.ac.uk/event/guest-lecture-series-2/#sthash.QrtLy0kV.dpuf
Year(s) Of Engagement Activity 2015
 
Description Guest Lecture #2 - Professor John Fisher at University of Bradford 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact The MeDe Innovation Guest Lecture Series is a programme of lectures led by its esteemed academic leadership in the field of innovative medical device manufacturing throughout 2015.

During the visit to a MeDe Innovation academic centre, the invited guest will present their research in a free to attend, open lecture. There are also other opportunities for the research community to engage in activities; such as ECR meetings, lab tours and the chance to present.

Attendees are invited from across the medical device manufacturing (Class III) sector.

Through the MeDe Innovation Guest Lecture Series, the research community can learn, meet, network, share experience, and build stronger cross-centre relationships.
- See more at: http://mede-innovation.ac.uk/event/guest-lecture-series-2/#sthash.QrtLy0kV.dpuf
Year(s) Of Engagement Activity 2015
 
Description Guest Lecture #3 - Professor David Grant at Newcastle University 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact The MeDe Innovation Guest Lecture Series is a programme of lectures led by its esteemed academic leadership in the field of innovative medical device manufacturing throughout 2015. During the visit to a MeDe Innovation academic centre, the invited guest will present their research in a free to attend, open lecture. There are also other opportunities for the research community to engage in activities; such as ECR meetings, lab tours and the chance to present. Attendees are invited from across the medical device manufacturing (Class III) sector. Through the MeDe Innovation Guest Lecture Series, the research community can learn, meet, network, share experience, and build stronger cross-centre relationships. - See more at: http://mede-innovation.ac.uk/event/guest-lecture-series-5-professor-david-grant-degradable-pvd-coatings-devices-musculoskeletal-applications/#sthash.UDotGxzE.dpuf
Year(s) Of Engagement Activity 2015
 
Description Guest Lecture #4 - Professor Paul Hatton at Nottingham 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact The MeDe Innovation Guest Lecture Series is a programme of lectures led by its esteemed academic leadership in the field of innovative medical device manufacturing throughout 2015. During the visit to a MeDe Innovation academic centre, the invited guest will present their research in a free to attend, open lecture. There are also other opportunities for the research community to engage in activities; such as ECR meetings, lab tours and the chance to present. Attendees are invited from across the medical device manufacturing (Class III) sector. Through the MeDe Innovation Guest Lecture Series, the research community can learn, meet, network, share experience, and build stronger cross-centre relationships. - See more at: http://mede-innovation.ac.uk/event/guest-lecture-series-5-professor-david-grant-degradable-pvd-coatings-devices-musculoskeletal-applications/#sthash.UDotGxzE.dpuf
Year(s) Of Engagement Activity 2015
 
Description Guest Lecture #5 - Professor Phil Coates at Sheffield 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact The MeDe Innovation Guest Lecture Series is a programme of lectures led by its esteemed academic leadership in the field of innovative medical device manufacturing throughout 2015.

During the visit to a MeDe Innovation academic centre, the invited guest will present their research in a free to attend, open lecture. There are also other opportunities for the research community to engage in activities; such as ECR meetings, lab tours and the chance to present.

Attendees are invited from across the medical device manufacturing (Class III) sector.

Through the MeDe Innovation Guest Lecture Series, the research community can learn, meet, network, share experience, and build stronger cross-centre relationships.
- See more at: http://mede-innovation.ac.uk/event/guest-lecture-series-2/#sthash.QrtLy0kV.dpuf
Year(s) Of Engagement Activity 2015
 
Description Hosted laboratory visit for Leeds Biomedical Research Centre Patient Public Involvement group 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Patients, carers and/or patient groups
Results and Impact Hosted a laboratory tour and series of talks from academic members of the Institute of Medical and Biological Engineering for members of the Leeds PPI group
Year(s) Of Engagement Activity 2018
URL https://youtu.be/cKfs50-NxJQ
 
Description IKC & Regener8 Annual Conference 2018 - Medtech innovation: best practice 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Louise Jennings (University of Leeds) & Laura Macri Pellizzeri (University of Nottingham) presented the joint research projects about Preclinical functional performance assessment of a new bio-inspired non-delaminating osteochondral construct using a physiological knee implantation model.
Year(s) Of Engagement Activity 2018
URL http://medical-technologies.leeds.ac.uk/event/ikc-regener8-annual-conference-2017-2/
 
Description IKC Regener8 Annual Meeting 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Featuring world-class speakers, oral and poster presentation sessions and interactive panel discussions, the Regener8 Annual Conference 2016 will provide an excellent opportunity to disseminate, share and discuss the impact of university-industry collaborations in the field of regenerative therapies and medical technologies.
Sessions include:
• High calibre, international keynote speaker
• Accelerating the development of regenerative devices nationally - presentations from our national partners on their proof of concept projects
• Sharing our expertise with other providers - presentations from our Arthritis Research UK funded projects
• Question panels
• Networking time, including poster presentations from our Early Career Researcher community
• Value delivered - presentations from our partners that have successfully delivered IKC POC projects that are progressing closer to clinic and the market
Community showcase: presentations from the community that are submitted, selected and delivered by you, the Regener8 and UK med tech community
Year(s) Of Engagement Activity 2016,2017,2018
 
Description Innovations in Biomedical Materials 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Uresha Patel, Zakir Hossain, Andy Kennedy, Alex Hannon, Emma Barney and Ifty Ahmed. Structural characterisation of calcium / strontium substituted phosphate-based glasse
Year(s) Of Engagement Activity 2014,2016
URL http://ceramics.org/biomed2016
 
Description Innovations in Biomedical Materials 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Ifty Ahmed, Uresha Patel, Zakir Hossain, Virginie Sottile, David Grant and Brigitte Scammell. Novel Porous Resorbable Calcium Phosphate Microspheres for Biomedical Applications.
Year(s) Of Engagement Activity 2016
URL http://ceramics.org/biomed2016
 
Description International Society for Fracture Repair 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A.J.B Parish, S Johnson, G Kesteloot & D.S McNally, Quantifying cervical fusion using porosity and directionality structural quantification of bone remodelling
Year(s) Of Engagement Activity 2016
URL https://www.ors.org/ors-isfr/
 
Description Interview for CCTV 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Interview of 3 leading UK people for opinion on developments in China, based on our experience - in my case research collaborations
Year(s) Of Engagement Activity 2017
 
Description Invited speaker from Netherlands (Nottingham, UK) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Dafydd Owen Visscher, PhD candidate at the department of Plastic, Reconstructive & Hand Surgery, gave a lecture about cartilage tissue engineering for craniofacial reconstruction.
Year(s) Of Engagement Activity 2016
 
Description LinkedIn Company Page 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The MeDe Innovation company page on LinkedIn provides a digital platform to share content to our audience.
Year(s) Of Engagement Activity 2015,2016,2017
URL https://www.linkedin.com/company
 
Description MEIbioeng15 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact The purpose of this workshop, held as part of the annual Medical Engineering Initiative (MEI) meeting, was to gather a diverse group of over 30 different stakeholders to discuss the opportunities and challenges of advancing knowledge and technology in the field of medical engineering and technology. Specifically, this MEI workshop chose to focus on the medical engineering landscape and the opportunities and challenges faced in the advancement of knowledge and technology and the translation of research. Over 30 people representing industry, the health service, regulators, investors, funders and academia participated in the workshop discussions.
Year(s) Of Engagement Activity 2015
 
Description MHRA Talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Medicines and Healthcare Products Regulatory Agency "Lunch and Learn" Seminar at the MHRA in London on "Making Bioactive Load Bearing Orthopaedic Devices In Clinic: New Possibilities and Challenges in Personalisation", 11th July, 2014.
Year(s) Of Engagement Activity 2014
 
Description Manufacturing Technologies Association - UK Manufacturing Review Book Launch 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact A published book containing an overview of the current centres of manufacturing within the UK (across all disciplines).
Year(s) Of Engagement Activity 2015
 
Description Manufacturing the Future (Cambridge, UK) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Leading UK academics, industrialists and senior government representatives attend the EPSRC Manufacturing the Future Conference to discuss how new research and government programmes can best support the needs of the UK's key manufacturing sectors.
Year(s) Of Engagement Activity 2015
 
Description Manufacturing the Future (Cranfield, UK) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Leading UK academics, industrialists and senior government representatives attend the EPSRC Manufacturing the Future Conference to discuss how new research and government programmes can best support the needs of the UK's key manufacturing sectors.
We soft-launched MeDe Innovation at this event, developing discussions around potential collaboration with other Centres.
Year(s) Of Engagement Activity 2013
 
Description Manufacturing the Future (Glasgow, UK) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Leading UK academics, industrialists and senior government representatives attend the EPSRC Manufacturing the Future Conference to discuss how new research and government programmes can best support the needs of the UK's key manufacturing sectors.
Year(s) Of Engagement Activity 2014
 
Description Mayfest university fair 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Katherine Pitrolino Was part of a team on a stand at the university fair which showcased what science the DTC was involved in and gave practical examples of regenerative medicine research in action.
Year(s) Of Engagement Activity 2015
 
Description MeDe Ask the Experts event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact This event will provide an overview of research undertaken on the development of decellularised human tissues for clinical use through a collaboration between NHS Blood & Transplant Tissue & Eye Service (NHS BT TES) and the University of Leeds.

There will be an opportunity to gain an insight into the day to day processes that are carried out by NHS BT TES in procurement, storage and supply of human tissue allografts to the NHS in the UK and the processes undertaken to take research from the laboratory to clinical application.

Delegates will gain understanding of the regulations that govern undertaking research and development of GMP manufacturing processes for decellularised human tissues from the perspective of the human tissue authority.
Year(s) Of Engagement Activity 2018
 
Description MeDe Innovation 'Vlog like a Pro' workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact What does MeDe Innovation mean to you?

Show us on video what MeDe Innovation means to you and you could win a GoPro! Your video will also be showcased and judged at the final MeDe Innovation Annual Conference on 18th January, attracting more than 200 delegates from the medical devices innovation community.

This one day workshop will include:

introduction to audio production, editing and video production for YouTube
hands-on experience with your smartphone, ipad, GoPro or other handheld recording device
delivered by science journalist Richard Hollingham, a radio and TV reporter/producer with extensive BBC experience
You will then have until Thursday 14th December to create and submit your video
Year(s) Of Engagement Activity 2018
URL http://mede-innovation.ac.uk/event/workshop-video-filming-research-impact/
 
Description MeDe Innovation Annual Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The Advanced Manufacturing Research Centre (AMRC) in Sheffield was host to the fifth MeDe Innovation Annual Meeting in January this year, where over 150 delegates gathered to hear the latest developments in the changing landscape of design and manufacture for orthopaedic devices.

The programme was opened by Professor Paul Hatton who introduced the key note speakers, Dr Suzanne Halliday, Professor Tim Briggs and Professor Edward Draper, and their session 'responsible innovation and the manufacture of medical devices.'

After a lively Q&A with the key note panel, Dr Jo Dixon Hardy chaired the very popular 'poster pitch' session, where 33 selected researchers were given 1 minute to present an outline of their poster before lunch. This was well received, and increased engagement with posters over the lunchtime networking session.

During the lunch break, delegates were offered the opportunity to view several videos created by our Early Career Researchers, describing their research and secondment experiences, as part of our 'vlog like a pro' competition.

The afternoon session provided an overview of each MeDe Innovation research theme, with presentation from both co-investigators and researchers, before concluding with Professor Paul Hatton awarding prizes for 'best poster presentation' and 'most popular Vlog.'
Year(s) Of Engagement Activity 2014,2015,2016,2017,2018
URL http://mede-innovation.ac.uk/news-article/mede-innovation-annual-conference-2018-review/
 
Description MeDe Innovation Annual Conference 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact the conference will report on progress and advances in research, innovation, and translation of its three focus areas: New approaches to manufacturing at the point of need Manufacturing regenerative devices, biological and biomimetic scaffolds Stratified design and manufacture of orthopaedic implants The conference will include presentations and posters from industry, regulators clinicians and academic researchers, panel discussions, poster pitches and networking opportunities.
Year(s) Of Engagement Activity 2017
URL http://mede-innovation.ac.uk/event/mede-innovation-fourth-annual-conference/
 
Description MeDe Innovation Annual Review 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Glossy review of annual activity of the MeDe. Disseminate, share and discuss the impact of university-industry collaborations in the field of regenerative therapies and medical technologies. Includes case studies of MeDe projects, and funder metrics such as funding leveraged, numbers of people engaged, partners and collaborators.
Year(s) Of Engagement Activity 2015,2016,2017,2018
 
Description MeDe Innovation Ask the Expert: Bioprinting and Biofabrication 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Cell printing, cell/material co-processing and 3D bioprinting are growing research areas, with a range of techniques available with the potential to create and complex cell co-cultures, and pre-seeded tissue engineering scaffolds with gradient mechanical and biological properties. However, challenges remain in the productivity, reliability and repeatability of the techniques. This workshop will give an overview of the current research and commercial processing techniques, and offer attendees the opportunity to discuss the technologies with engineers and scientists who work with the techniques on a day-to-day basis.

The workshop will be useful for attendees who are curious about bioprinting and biofabrication, for attendees planning to use bioprinting and biofabrication in the future, and for those already using bioprinting and biofabrication techniques but who want to broaden their knowledge.
Year(s) Of Engagement Activity 2017
URL http://mede-innovation.ac.uk/event/mede-innovation-ask-expert-bioprinting-biofabrication/
 
Description MeDe Innovation Ask the Expert: Clinically-led manufacture of custom-made collagen membranes 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact This event will highlight key performance requirements and future needs for the scalable manufacture of next-generation collagen-based biomaterials from the perspective of both an orthopaedic and a periodontal surgeon, together with a medical device manufacturer specialising in bone and cartilage regeneration.

Collagen-based membranes are important for replacement or reinforcement of connective tissues, and as occlusive barriers in Guided Bone Regeneration (GBR) and Guided Tissue Regeneration (GTR). Application areas include periodontal, maxillofacial and orthopaedic surgery, where the biocompatibility, degradability and versatility of collagen-based membranes are highly prized. As clinical procedures continue to advance in various fields of surgery, new functional demands are being placed on the specifications of collagen-based membranes with regard to properties such as long-term stability, mechanical properties, adhesion and the ability to control biofilm infection. New manufacturing techniques based on hydrogels, fibres and nonwovens are also in development providing new physical formats and routes to customisation.

This workshop will give an overview of clinical needs, methods of manufacture and performance requirements, with the opportunity for attendees to discuss requirements and challenges with clinical specialists, engineers and product manufacturers.
Year(s) Of Engagement Activity 2018
URL http://mede-innovation.ac.uk/event/mede-innovation-ask-expert-oct-18/
 
Description MeDe Innovation Conference (Newcastle) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact the conference will report on progress and advances in research, innovation, and translation of its three focus areas:

New approaches to manufacturing at the point of need
Manufacturing regenerative devices, biological and biomimetic scaffolds
Stratified design and manufacture of orthopaedic implants

The conference will include presentations and posters from industry, regulators clinicians and academic researchers, panel discussions, poster pitches and networking opportunities.
Year(s) Of Engagement Activity 2016
 
Description MeDe Innovation Launch Conference (Leeds) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Launch of MeDe Innovation: Delegates heard from respected industry and academic experts and learnt how the Centre is stimulating translation and connecting the medical device community in the UK in order to accelerate manufacturing processes through to business and the clinic.
Year(s) Of Engagement Activity 2014
 
Description MeDe Innovation Launch Conference (Nottingham) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The MeDe Innovation Annual Conference 2015 'Advancing Orthopaedic Medical Device Manufacturing' will bring you up to the minute developments in the changing landscape of design and manufacture for orthopaedic medical devices.

Our interdisciplinary one-day conference brings together experts from funders, research, industry, clinical, and regulation. A year on from our launch event, delegates will have the opportunity to consider:

Medical Devices - An industry with unlimited potential:

Opportunities and challenges in

stratified design and innovative manufacture of orthopaedic medical devices
in-clinic manufacture of personalised orthopaedic devices
use of biological and biomimetic materials in medical devices and health technologies

Getting great products to patients:

Regulatory perspectives from the MHRA towards personalised and combination approaches for medical devices
Changes to the pre-market approvals process to access opportunities in the USA from the FDA Centre for Devices and Radiological Health

Creating new industries from pioneering innovative manufacturing research in the UK:

Showcase of how EPSRC are creating a prosperous future for the UK through ground-breaking innovative manufacturing research
How breadth of research is growing new technology-led companies, improving healthcare delivery and allowing economic competitiveness in the UK
Presentations from research specialists in Additive Manufacturing, Composite Manufacturing and more

Growing and supporting the national community

Announcement of the Fresh Ideas Award winners from the Centre Co-Director
Growing a Medical Devices and Regenerative Clinical Network led by the Centre Clinical Director
Launch of the National MSK Medical Device Capability Database from the Centre National Outreach Manager
Ample networking opportunities, exhibitions and panel discussion sessions
Year(s) Of Engagement Activity 2015
 
Description MeDe Innovation Mid Term Review 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The MeDe Innovation mid-term review was conducted for the EPSRC to establish the progress of the grant at the half way (2.5 year) mark.

A panel was constructed of External Advisory Board members (industry/academic/clinical) and presentations were given on current research projects. The panel also asked a number of questions to the MeDe Innovation executive board which then fedback into a final report.

The Early Career Researchers also hosted a poster presentation session after the main meeting, to showcase current projects.
Year(s) Of Engagement Activity 2016
 
Description MeDe Innovation PhD Seceondment Scheme 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact MeDe Innovation funded 7 PhD secondments up to the value if £1500 each.

Secondments took place regionally, nationally and internationally, and have been a very valuable experience for the students.

Each researcher has written a blog post about their secondment opportunity and how it has helped their progression.
Year(s) Of Engagement Activity 2016,2017
 
Description MeDe Innovation Twitter feed 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact The MeDe Innovation Twitter feed is a social media platform used to push out updates from the centre.
Year(s) Of Engagement Activity 2014,2015,2016,2017
URL https://twitter.com/MeDe_Innovation
 
Description MeDe Innovation annual conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact 2 minute poster pitch and poster presentation at MeDe Innovation annual conference.
Year(s) Of Engagement Activity 2017
URL http://mede-innovation.ac.uk/event/mede-innovation-fifth-annual-conference/
 
Description MeDe Innovation quarterly newsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Our quarterly MeDe Innoavation newsletter features 6-8 of our key news items/events over a three month period, and is circulated to our entire contacts list and also pushed out via the website, twitter and LinkedIn pages.
Year(s) Of Engagement Activity 2014,2015,2016,2017
 
Description MeDe Innovation website 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The MeDe Innovation website updates our audience on events, news articles, research opportunities and gives an overview of the aim of the centre.
Year(s) Of Engagement Activity 2014,2015,2016,2017
URL http://mede-innovation.ac.uk/
 
Description Medipex Innovation Awards 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Medipex NHS Innovation Awards bring together the most innovative & exciting people from the region's NHS & commercial healthcare sector. Over 12 years, the event has established a reputation for showcasing outstanding projects and initiatives from across Yorkshire, Humber and East Midlands regions, providing a unique insight into up and coming new innovations and thinking from the NHS.
We are delighted to be able to offer the opportunity for a small number of Companies to be involved. Sponsorship allows organisations be directly associated with the NHS innovation agenda and offers significant publicity opportunities. Attendance at the awards event also provides a unique opportunity to network with key NHS and healthcare business leaders.
Year(s) Of Engagement Activity 2016,2017,2018
 
Description Ministerial visit 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Article about Lord Pryor's visit to iMBE. Government Health Minister Lord Pryor met iMBE Director Professor Ruth Wilcox, heard an extensive presentation from Professor Paul Emery. He was shown the operation of the Leeds IKC and visited iMBE laboratory facilities to view the technical equipment used to produce world-leading research results.
Year(s) Of Engagement Activity 2016
 
Description Newspaper article: University helps improve medical implants - Yorkshire Post 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Story on the output of project POC018 - Electromechanical hip simulator method SOP (standard operating procedure) and training. The story covered how the research and project is helping improve safety in medical devices in China.

Test test test
Year(s) Of Engagement Activity 2013
URL http://www.yorkshirepost.co.uk/business/business-news/university-helps-firm-improve-medical-implants...
 
Description Now is the time to invest in medical technologies sector 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Interview with Professor John Fisher, Director of the Institute for Medical and Biological Engineering, University of Leeds, about pioneering research in the fields of medical devices and regenerative medicine
Year(s) Of Engagement Activity 2018
URL http://www.opnews.com/2018/01/now-time-invest-medical-technologies-sector/14260
 
Description Orthopaedic Knee Conference 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact This scientific meeting will aim to tackle current trends and topics as well as raise future surgical concepts and innovations. The one-day meeting will discuss topics including NJR / Beyond Compliance issues, Total knee arthroplasty and sessions on uni-knee replacement and soft tissue. It promises to be a highly stimulating event and a great educational resource for all delegates. Whether you're an orthopaedic knee surgeon, medical professional, medical device manufacturer, or associated with another related field, this is an essential event for your diary. The meeting will comprise keynote lectures for our plenary sessions, open panel debates and a lively trade exhibition.
Year(s) Of Engagement Activity 2016,2017
 
Description Orthopaedic Knee Conference 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact This scientific meeting will aim to tackle current trends
and topics as well as raise future surgical concepts and
innovations. The one-day meeting will discuss topics
including NJR / Beyond Compliance issues, Total knee
arthroplasty and sessions on uni-knee replacement and soft
tissue. It promises to be a highly stimulating event and a
great educational resource for all delegates.
Year(s) Of Engagement Activity 2016
URL http://www.opnews.com/programme
 
Description Oxford 3D 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Presentation for The University of Oxford 3D Printing Society and Digital Health Oxford, "Practical Bioprinting", 3rd December, 2015.
Year(s) Of Engagement Activity 2015
 
Description P70 - Polymer Process Engineering Conference Bradford 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Gathering of international colleagues from academy, industry and government, (including the Chinese Ambassador to the UK) for leaders and early career researchers, with technical sessions, laboratory demonstrations and good social opportunities. Marking the 70th birthday of MeDe PI Phil Coates.
Year(s) Of Engagement Activity 2018
 
Description PPE Bradford 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact • To provide a technical focus for the polymer processing and technology industries
• To discuss key developments in engineering excellence in polymer processing
• To discuss recent developments in Advanced Materials in Healthcare and Medical Devices (focusing on MeDe Challenge 2, MeDe presentations are integral to this meeting)
• To raise awareness of leading edge developments in polymer processing technology, in-process measurements and process flow modelling, and control
Year(s) Of Engagement Activity 2015
 
Description PR around winning The Engineer Collaborate to Innovate Awards 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Online article profiling EPSRC Centre for Innovative Manufacturing in Medical Devices (MeDe Innovation) - winner of the Academic Innovator Award at the Engineer Collaborate To Innovate (C2I) Awards.
Year(s) Of Engagement Activity 2017
URL https://www.theengineer.co.uk/c2i-2017-medical-devices-sector/
 
Description Pint of Science 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation on "3D Printing for Medical Devices and Tissues" as part of Newcastle Pint of Science Festival 2018
Year(s) Of Engagement Activity 2018
 
Description Polymer Process Engineering 17 conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Exhibited the Translate: programme
Year(s) Of Engagement Activity 2017
 
Description Polymer Processing Society Conference (Graz, Austria) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Gabriel Choong gave a presentation about Rheological Techniques for Determining Degradation of Polylactic Acid in Bioresorbable Medical Polymer Systems.
Year(s) Of Engagement Activity 2015
URL http://www.pps2015graz.com/en/
 
Description Polymer Processing Society Conference (Graz, Austria) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Magdalena T. Tomczynska presented her PhD work about Compounding and rheometry of PLA nanocomposites with coated and raw hydroxyapatite nanoplatelet.
Year(s) Of Engagement Activity 2015
URL http://www.pps2015graz.com/en/
 
Description Presentation and UKSB an d ESB on Manufacture of Fully Bioresorbable Composites as Fracture Fixation Devices 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Participants in your research and patient groups
Results and Impact Discussion

Future collaboartions
Year(s) Of Engagement Activity 2014
URL http://esb2014.org/uksb-registration-form/
 
Description Presentation to UKSB and ESB 2014 on Phosphate Glass Coatings for Improved Osseointegration Applied By RF Magnetron Sputtering 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Participants in your research and patient groups
Results and Impact Dissemination

Future collaborations
Year(s) Of Engagement Activity 2014
URL http://esb2014.org/uksb-registration-form/
 
Description Putting next generation knee implants through their paces 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Feature article in which Louise Jennings (MeDe Innovation) and Ian Revie (Invibio) discuss how the techniques and equipment designed by MeDe researchers are being used, not only to evaluate existing devices, but also to support the development of new designs using novel materials - paving the way for new types of implant that are better tailored to individual patients
Year(s) Of Engagement Activity 2018
 
Description RSC Biomaterials Special Interest Group Annual Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Caitriona McCarron, Virginie Sottile, Brigitte Scammell and Ifty Ahmed. Investigation of Resorbable Invert Phosphate Based Glasses for Orthopaedic Applications. Royal Society of Chemistry Biomaterials Conference
Year(s) Of Engagement Activity 2017
URL http://www.rsc.org/events/detail/24301/rsc-biomaterials-special-interest-group-annual-meeting-2017
 
Description SAMPE China 2016 Conference and exhibition 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Yunqi Wang, Xiaoling Liu, Chenkai Zhu, Andrew Parsons, Jinsong Liu, Ifty Ahmed, Chris Rudd, Novel phosphate glass fibre textile composites for implants
Year(s) Of Engagement Activity 2016
URL https://www.sampe-europe.org/news/2016/sampe-china-2016-international-conference-exhibition
 
Description SPE International Award in Plastics News (USA based publication, also in Europe and Asia) 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Announcement of the Society of Plastics Engineers Intenational award, the top award of the SPE, to Prof Phil Coates. This increases the visibility of the UK in the polymer engineering research area, where Prof Coates directs the world-leading Polymer IRC. The Award will be presented in May 2018 at the SPE major international conference, with a Plenary lecture.
Year(s) Of Engagement Activity 2018
URL http://www.plasticsnews.com/article/20180222/NEWS/180229963/spe-names-annual-award-winners-antec-spe...
 
Description School visit to deliver seminar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Education of sixth form children about strategies in regenerative medicine with a focus on regenerative devices
Year(s) Of Engagement Activity 2017
 
Description Science and Innovation Audit published - Medical Technologies in the Leeds City Region 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Science and Innovation Audit, commissioned by the Department of Business, Energy and Industrial Strategy (BEIS), highlighting investment opportunities for medical technologies.

Led by Professor John Fisher from the University of Leeds, in partnership with the Leeds Enterprise Partnership (LEP), the region's universities and local businesses.
Year(s) Of Engagement Activity 2017
URL https://medical-technologies.leeds.ac.uk/news-post/science-and-innovation-audit-published/
 
Description Sichuan University article following top China Award to Prof Phil Coates in Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Sichuan University article, after the Award Ceremony for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. He is an Honorary Professor and High End Foreign Professor of Sichuan University, who are one of the main collaborators with Bradford and others in our ongoing Science Bridges China programme. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.scu.edu.cn/en/news/webinfo/2018/01/1514127424326967.htm
 
Description Society of Glass Technology (Sheffield, UK) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Bryan Sturat presented his PhD work about Structural Variability and Dissolution Characteristics of RF Magnetron Sputtered Ion Doped Phosphate Based Glass Coatings
Year(s) Of Engagement Activity 2016
URL http://www.centenary.sgt.org/Conference.htm
 
Description Society of Glass Technology: Centenary Conference & 13th Symposium of the European Society of Glass Science and Technology. Glasses in Healthcare - Hench Memorial Symposium 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Bryan W. Stuart, M. Gimeno-Fabra, J. Segal, I. Ahmed and D.M. Grant. Structural Variability and Dissolution Characteristics of RF Magnetron Sputtered Ion-Doped Phosphate Based Glass Coatings
Year(s) Of Engagement Activity 2008,2016
URL http://www.centenary.sgt.org/
 
Description Society of Glass Technology: Centenary Conference & 13th Symposium of the European Society of Glass Science and Technology. Glasses in Healthcare - Hench Memorial Symposium 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Md Towhidul Islam, Kazi M. Zakir Hossain, Nusrat Sharmin, Andrew J. Parsons & Ifty Ahmed. In vitro bioactivity and degradation studies of novel phosphate-based glasses for biomedical applications
Year(s) Of Engagement Activity 2016
URL http://www.centenary.sgt.org/
 
Description Society of Glass Technology: Centenary Conference & 13th Symposium of the European Society of Glass Science and Technology. Glasses in Healthcare - Hench Memorial Symposium 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Ifty Ahmed, Uresha Patel, Zakir Hossain, Virginie Sottile, David Grant and Brigitte Scammell. Novel microstructural features in phosphate glass microspheres for cell and biomaterial interactions.
Year(s) Of Engagement Activity 2016
URL http://www.centenary.sgt.org/
 
Description State of the City Meeting - The Future of Manufacturing 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Medical technology - bringing together precision engineering with healthcare - is a field where Leeds has some world leading companies. We also have, in the University of Leeds, one of the country's leading research institutions in engineering and health. This workshop explores the possibilities that this sector brings, focussing on DePuy and Brandon Medical, two Leeds-based companies with global reputations, and on the University's research excellence. The speakers will describe the kind of work that is involved in medical technology innovation, and the sector's role in the future of the city.
Year(s) Of Engagement Activity 2012,2015
 
Description TERMIS-EU 2016 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact D.Gupta, K. Hossain, I. Ahmed, D Grant and V. Sottile. Biological evaluation of degradable phosphate-based glass microspheres for stem cell therapy
Year(s) Of Engagement Activity 2016
URL https://www.termis.org/eu2016/
 
Description TI World Conference Programme - Keynote 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Keynote presentation on textile medical devices and healthcare to the World Textile Institute Conference
Year(s) Of Engagement Activity 2018
URL http://www.tiworldconference.org/wp-content/uploads/2015/04/TIWC-2018-Programme-Final1.pdf
 
Description Television programme "Who wants to live forever" ITV 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact ITV Tonight Programme, aired 7:30pm, Thursday 5 July 2012. A look at how thousands are now celebrating their one hundredth birthday. John Fisher and Eileen Ingham present their research around "50 Active years after 50" as part of the programme.

Further requests from TV producers about health innovations of the future.
Year(s) Of Engagement Activity 2013
URL https://www.itv.com/itvplayer/tonight/series-16/episode-5-who-wants-to-live-forever-
 
Description Termis - Americas 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Tronci G; Liang H; Wood DJ; Russell SJ (2017) Functionalised Collagen Systems With Bespoke Molecular And Macroscopic Characteristics For Chronic Wound Management 2017 TERMIS - Americas Conference & Exhibition, pp. S74-S74. Charlotte, NC
Year(s) Of Engagement Activity 2017
 
Description The 15th Annual United Kingdom Society for Biomaterials (UKSB) (London) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Adi Zabidi had a poster about relationship between dimensions and stiffness of Schwarz P Unit cell based tissue engineering scaffolds.
Year(s) Of Engagement Activity 2016
URL https://sites.google.com/a/my.westminster.ac.uk/uksb2016/home
 
Description The Engineer C2I Winners Showcase 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Magazine profiling a winners' showcase at the Engineer Collaborate To Innovate (C2I) Awards. Includes a profile of EPSRC Centre for Innovative Manufacturing in Medical Devices (MeDe Innovation) - winner of the Academic Innovator Award.
Year(s) Of Engagement Activity 2018
 
Description The Engineer c2i Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Invited presentation at The Engineer Magazine Collaborate2Innovate Conference in Coventry, 7th December 2017
Year(s) Of Engagement Activity 2017
 
Description The Rheology Workshop (Nottingham, UK) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Magda Tomczynska presented her PhD work about Extrusion and compounding of degradable polymer nanocomposites.
Year(s) Of Engagement Activity 2014
 
Description Top three conferences of 2018 so far 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 3DMedNet team profiles the conferences and events they have attended, focusing on the latest projects and ideas in the 3D medical printing community. The MeDe Innovation Fifth Annual Conference in Sheffield is highlighted as one of their top 3 conferences for 2018.
Year(s) Of Engagement Activity 2018
URL https://www.3dmednet.com/users/78640-georgi-makin/posts/30549-top-three-conferences-of-2018-so-far
 
Description UK Manufacturing Review 2017   
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Article reviewing the EFF Future Manufacturing Works, including a profile of MeDe Innovation as winner of the Academic Innovator Award at the Engineer's Collaborate to Innovate (C2I) Awards.
Year(s) Of Engagement Activity 2018
 
Description UK Society for Biomaterials 17th Annual Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Matthew Wadge presented his research on bioactive titanate surfaces and won the best oral presentation in the conference.
Year(s) Of Engagement Activity 2018
URL https://www.uksb.org.uk/uksb2018
 
Description UK Society for Biomaterials 17th Annual Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Kathryn Thomas presented her research on sacrificial phosphate based glass coatings for in vivo biofilm prevention.
Year(s) Of Engagement Activity 2018
URL https://www.uksb.org.uk/uksb2018
 
Description UoN 2018 Polymer Science and Engineering Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Reda Felfel presented his research on polymers and polymer composites for biomedical applications.
Year(s) Of Engagement Activity 2018
 
Description Visit to Birmingham Orthopaedic hospital (Birmingham, UK) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Pitrolino Katherine went to Birmingham Orthopaedic hospital to gain a clinicians point of view regarding bilyaer chitosan scaffold for osteochondral defects
Year(s) Of Engagement Activity 2017
 
Description Visit to Department of Design and Non-Woven Textiles, University of Leeds 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Exploring future potential of energy and bio applicable textiles in advanced materials applications
Year(s) Of Engagement Activity 2017
 
Description Visit to Evonik Nutrition and Care GmbH, Germany 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Magdalena M Patel was awarded funding from MeDe ECR PhD Student Secondment Scheme which enabled her to work for one month at Evonik in Darmstadt in Germany. During this placement, she participated in production of composites dedicated for orthopaedic implants with Evonik biodegradable materials and gained industrial insight on manufacturing of biomedical polymers.
Year(s) Of Engagement Activity 2016
 
Description World Biomaterials Congress (Montreal, Canada) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Bryan Sturat had a poster about RF Magnetron Sputtering of Bioresorbable Ion Doped Bioactive Glass Coatings
Year(s) Of Engagement Activity 2016
URL http://wbc2016.org/index.php/wbc-2016
 
Description World Biomaterials Congress (Montreal, Canada) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Reda Felfel gave a presentation about In vitro degradation and cytocompatibility of PLA-PCL copolymer unit cell scaffolds.
Year(s) Of Engagement Activity 2016
URL http://wbc2016.org/index.php/wbc-2016
 
Description Xinhua article on China Award for Prof Coates 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Xinhua press article in Beijing, after the Award Ceremony for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.xinhuanet.com/english/2018-01/08/c_136880680_10.htm
 
Description article in China Daily, 19 Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Interview of Prof Coates by China Daily in Beijing, after he received the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, from President Xi Jinping and other leaders. This is the top award in China for foreigners. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.chinadaily.com.cn/a/201801/19/WS5a61c69fa3106e7dcc13562d.html
 
Description visit to Johnson Matthey in Sonning (UK) and their manufacturing facility in Maastricht (Netherlands) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Ifty Ahmed and George Rice visited Johnson Matthey in Sonning (UK) and their manufacturing facility in Maastricht (Netherlands) in Nov 16. They have had lots of meetings and discussions and this led to submitting an application to IKC Proof of Concept Awards in Regenerative Medical Devices & Medical Devices with Enhanced Regenerative Functions - Industry Partnership Call.
Year(s) Of Engagement Activity 2016