Sound bullets for enhanced biomedical ultrasound systems

Lead Research Organisation: University of Leeds
Department Name: Electronic and Electrical Engineering

Abstract

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Publications

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Askari M (2020) Additive manufacturing of metamaterials: A review in Additive Manufacturing

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Askari M (2020) An ultrasonic metallic Fabry-Pérot metamaterial for use in water in Additive Manufacturing

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Harput S (2014) Superharmonic imaging with chirp coded excitation: filtering spectrally overlapped harmonics. in IEEE transactions on ultrasonics, ferroelectrics, and frequency control

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Adams C (2017) An Adaptive Array Excitation Scheme for the Unidirectional Enhancement of Guided Waves. in IEEE transactions on ultrasonics, ferroelectrics, and frequency control

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Smith PR (2013) Width-modulated square-wave pulses for ultrasound applications. in IEEE transactions on ultrasonics, ferroelectrics, and frequency control

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Adams C (2018) HIFU Drive System Miniaturization Using Harmonic Reduced Pulsewidth Modulation. in IEEE transactions on ultrasonics, ferroelectrics, and frequency control

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Adams C (2020) HIFU Power Monitoring Using Combined Instantaneous Current and Voltage Measurement. in IEEE transactions on ultrasonics, ferroelectrics, and frequency control

 
Description The research developed new methods to convert simple excitation signals into broadband signals suitable for imaging. The technology is based on solitary waves progressing in closely grouped spheres, similar to newtons cradle but on the micro-scale.

In this study, an analytical model is created to predict the motion of a finite material attached to a granular chain as a matching layer. An experimental setup is created to verify the estimated motion of the matching material with the new model. The setup consists of a one-dimensional chain of six aluminum spheres, a vitreous carbon matching layer, and an ultrasonic horn. The ultrasonic horn generates a narrow-band input of a 25-cycle sinusoidal tone burst with a center frequency of 73 kHz and a-6-dB bandwidth of 3.5 kHz.The output is measured in water as a train of wideband ultrasonic pulses with a-6-dB bandwidth of 280 kHz,which is predicted with the model as 252 kHz. The results derived in this research work indicate that such chain like systems may be of interest to the biomedical ultrasound community,where a train of high-frequency impulses might have applications in imaging, microbubble dynamics, and high-intensity therapy
Exploitation Route The technology could eventually lead to new types of transducers that can be used for both diagnostic imaging and therapeutic purposes.
Sectors Electronics,Healthcare

 
Description The research findings are early stages but have been extensively published. The collaboration have led on to two successful grants "Therapy Ultrasound Network for Drug Delivery & Ablation Research (ThUNDDAR) Grant Reference: EP/N026942/1 with UCL, Imperial, ICR and Oxford and proposal EP/N034813/1 High Resolution Biomedical Imaging Using Ultrasonic Metamaterials with Warwick and Nottingham. Progressing the findings in both application led healthcare domain (therapeutic ultrasound) and physical metamaterials research.
First Year Of Impact 2015
Sector Education,Electronics,Healthcare,Manufacturing, including Industrial Biotechology
 
Description Responsive Mode
Amount £830,216 (GBP)
Funding ID EP/N034813/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 12/2016 
End 11/2019
 
Description Sound bullets for enhanced biomedical ultrasound systems 
Organisation University College London
Department Mechanical Engineering
Country United Kingdom 
Sector Academic/University 
PI Contribution Physical acoustics and advanced simulation of nonlinear systems.
Collaborator Contribution Experimental facilities including rapid prototyping of a new solitary wave transducer array.
Impact Yes this collaboration is multidisciplinary. 1. There has been a submitted grant on Metamaterials with Warwick 2. The formation of a successful grant for Healthcare Network Plus with UCL (Therapy Ultrasound Network for Drug Delivery & Ablation Research (ThUNDDAR) Grant Reference: EP/N026942/1)
Start Year 2014
 
Description Sound bullets for enhanced biomedical ultrasound systems 
Organisation University College London
Department Mechanical Engineering
Country United Kingdom 
Sector Academic/University 
PI Contribution Contribution of acoustic experimental facilities to Warwick as part of the grant. Contribution of robotics fabrication facilities as part of the grant
Collaborator Contribution Contribution of simulation facilities by UCL Contribution of micro-fabrication facilities from Warwick
Impact Warwick, School of Engineering (EP/K030159/1) UCL Mechanical Engineering (EP/K032070/1
Start Year 2014
 
Description Sound bullets for enhanced biomedical ultrasound systems 
Organisation University of Warwick
Department School of Engineering
Country United Kingdom 
Sector Academic/University 
PI Contribution Contribution of acoustic experimental facilities to Warwick as part of the grant. Contribution of robotics fabrication facilities as part of the grant
Collaborator Contribution Contribution of simulation facilities by UCL Contribution of micro-fabrication facilities from Warwick
Impact Warwick, School of Engineering (EP/K030159/1) UCL Mechanical Engineering (EP/K032070/1
Start Year 2014