Developing the NanoKick bioreactor to enable tissue engineered bone graft and use of metabolomics to identify bone specific drug candidates
Lead Research Organisation:
University of the West of Scotland
Department Name: School of Engineering
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
People |
ORCID iD |
| Stuart Reid (Principal Investigator) | |
| Kenny Cameron (Co-Investigator) |
Publications
Childs PG
(2016)
Use of nanoscale mechanical stimulation for control and manipulation of cell behaviour.
in Acta biomaterialia
Robertson S
(2017)
Investigation of the antimicrobial properties of modified multilayer diamond-like carbon coatings on 316 stainless steel
in Surface and Coatings Technology
Robertson SN
(2020)
Reduction of Pseudomonas aeruginosa biofilm formation through the application of nanoscale vibration.
in Journal of bioscience and bioengineering
Tsimbouri PM
(2017)
Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor.
in Nature biomedical engineering
| Description | Progression of Nanokick technology to the point where patent submitted (GB201514734A) and the first in man study has been funded, see: http://www.findabetterway.org.uk/news/synthetic-bone-project-full-swing/ |
| Exploitation Route | Progression of Nanokick technology to the point where patent submitted (GB201514734A) and the first in man study has been funded, see: http://www.findabetterway.org.uk/news/synthetic-bone-project-full-swing/ |
| Sectors | Healthcare,Pharmaceuticals and Medical Biotechnology |
| URL | http://www.nanokick.com |
| Description | Progression of Nanokick technology to the point where patent submitted (GB201514734A) and the first in man study has been funded, see: http://www.findabetterway.org.uk/news/synthetic-bone-project-full-swing/ In addition, significant engagement with clinicians and in public engagement, e.g.: https://royalsociety.org/science-events-and-lectures/summer-science-exhibition/exhibits/stem-cells-nano-kicking/ |
| First Year Of Impact | 2016 |
| Sector | Healthcare,Pharmaceuticals and Medical Biotechnology |
| Impact Types | Societal |
| Description | GLORI - Glasgow Orthopaedic Research Initiative |
| Organisation | Queen Elizabeth University Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Presented invited talk at 2018 conference. |
| Collaborator Contribution | Linking with clinicians working on orthopaedics to support translation of biomedical research (particularly Nanokicking) to clinic. |
| Impact | Strengthening of collaborations which are associated with nanokicking grants. |
| Start Year | 2009 |
| Description | GLORI - Glasgow Orthopaedic Research Initiative |
| Organisation | University of Glasgow |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Presented invited talk at 2018 conference. |
| Collaborator Contribution | Linking with clinicians working on orthopaedics to support translation of biomedical research (particularly Nanokicking) to clinic. |
| Impact | Strengthening of collaborations which are associated with nanokicking grants. |
| Start Year | 2009 |
| Description | Scottish Centre for Innovation in Spinal Cord Injury (SCISCI) |
| Organisation | Queen Elizabeth University Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Attended meetings and discussions. Submitted STFC CLASP proposal in partnership with SCISCI. |
| Collaborator Contribution | Supported collaborative STFC CLASP grant Proposal |
| Impact | Grant proposal submitted. |
| Start Year | 2015 |
| Title | Mechanical bioreactor |
| Description | https://patents.google.com/patent/GB201514734D0/en |
| IP Reference | GB201514734D0 |
| Protection | Patent application published |
| Year Protection Granted | 2017 |
| Licensed | No |
| Impact | Development of stem cell derived osteoblasts (bone building cells) for research, drug discovery, and regenerative medicine (surgical bone graft). |
| Description | BBC Radio World Service Interview |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Interviews throughout 29th December 2017 in relation to the Find A Better Way (FABW) landmine charity, which funded technology that was used to save the leg of a canine patient (Eva the dog). |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.findabetterway.org.uk/news/extensive-bbc-coverage-synthetic-bone-project/ |
| Description | BlueDot Music Festival - talk on gravitational waves |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | BlueDot |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.discoverthebluedot.com |
| Description | Careers networking event - Morrisons Academy high school, Crieff, Perthshire |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Presented my research areas (gravitational waves, nanokicking/stem cells) and described career opportunities within physics and biomedical engineering. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://twitter.com/macmorrisons/status/971349384926519296 |
| Description | Invited public talk at Joint Congress of University Astronomical Societies, Galway, Ireland (Mar 2019) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Invited public talk at Joint Congress of University Astronomical Societies, Galway, Ireland (Mar 2019) |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited seminar/colloquim, University of Glasgow (UK) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited talk on Nanokicking (stem cell) research. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Invited talk to the Renfrewshire Astronomical Society, Paisley |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Invited talk to the Renfrewshire Astronomical Society, Paisley |
| Year(s) Of Engagement Activity | 2017 |
| Description | Invited talk to the Stirling Astronomical Society, Paisley. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | as above |
| Year(s) Of Engagement Activity | 2017 |
| Description | Keynote public lecture for the British Orthopaedic Research Society (BORS). |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | BORS |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://borsoc.org.uk/ |
| Description | National coverage on BBC Radio Scotland - Good Morning Scotland show - interview regarding STFC-CLASP project for possible treatment of disuse osteoporosis |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | National coverage on BBC Radio Scotland - Good Morning Scotland show - interview regarding STFC-CLASP project for possible treatment of disuse osteoporosis |
| Year(s) Of Engagement Activity | 2019 |
| Description | Public talk with Prof. Andrew Hart (Plastic Surgeon), Clinicians in Research Network |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | n/a |
| Year(s) Of Engagement Activity | 2016 |
| Description | Radio 4 PM - live interview - Eva the dog story (bone regeneration to save her leg) |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interviews throughout 29th December 2017 in relation to the Find A Better Way (FABW) landmine charity, which funded technology that was used to save the leg of a canine patient (Eva the dog). |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.findabetterway.org.uk/news/extensive-bbc-coverage-synthetic-bone-project/ |
| Description | Re-write the Headlines activity with local school - 1 workshop session - Kingcase Primary school (UK) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Workshop |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://researchtheheadlines.org |
| Description | Royal Society Summer Science Exhibition - Giving Stem Cells A Good (Nano)kicking |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | 14500 visitors over 7 days. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.nanokick.com |
| Description | Science in Parliament event - Scottish Government - Society of Chemical Industry (SCI) stand - Reid to lead |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Science and Parliament engagement event, organised by the Royal Society of Chemistry |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://www.rsc.org/events/detail/19918/Science%20and%20the%20Parliament%202015 |
| Description | The Borders Science Festival (Peebles public library) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Public talk on gravitational wave detection at the Borders Science Festival |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.google.co.uk/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&cad=rja&uact=8&ved=0ahUKEwjRx-Pp-9... |