Enabling industrial deployment of deep eutectic solvents through manufacturing tools

Lead Research Organisation: University of Cambridge
Department Name: Chemical Engineering and Biotechnology

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
 
Description In this project, we are exploring the role of a new type of green, no-toxic and biodegradable type of solvents, deep eutectic solvents, in a range of applications, namely as solvents in organic transformations and also for the synthesis of metal nanoparticles and nanostructured materials.
This project is part of a small consortium where our role is the development of flow reactors to enable the deployment of the abovementioned systems. One of the main challenges is the high viscosity associated to these green solvents, which we have overcome by their mixing with water in particular ratios so the structure of the solvent is not modified.

As part of the project, we have demonstrated:
- The synthesis of nanostructured ceria in deep eutectic solvents using a flow reactor
- The deployment of flow reactors for organometallic reactions using air sensitive organo-lithium catalysts. By combining the different expertise brought by the consortium, we have demonstrated for the first time these reactions in flow, opening the door to a range of opportunities, specially in the pharmaceutical industry.
Exploitation Route We are currently engaging with industry to explore knowledge transfer routes.
Sectors Chemicals,Energy,Environment,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology
 
Title Research data supporting: Continuous, stable and safe organometallic reactions inflow at room temperature assisted by deep eutectic solvents 
Description The video data is related to the publication entitled "Continuous, stable and safe organometallic reactions in flow at room temperature assisted by deep eutectic solvents". The supporting media contains: * Hydrodynamic studies using segmented flow between the DES or DES/aqueous phase and the organic phase containing the substrate. For further information please refer to the publication and the video. * NMR data 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? Yes  
URL https://www.repository.cam.ac.uk/handle/1810/334274
 
Description Eva Hevia 
Organisation University of Bern
Country Switzerland 
Sector Academic/University 
PI Contribution This is a collaboration project together. They are developing new chemistries using deep eutectic solvents which we are translating into continuous flow systems for their adaptation in industry.
Collaborator Contribution They are exploring the use of deep eutectic solvents in organic reactions using air-sensitive catalysts.
Impact We are currently drafting the first join publication together.
Start Year 2019
 
Description Karen Edler 
Organisation University of Bath
Country United Kingdom 
Sector Academic/University 
PI Contribution Developing flow systems for the synthesis of nanostructured materials using deep eutectic solvents
Collaborator Contribution Understanding the interaction and role of deep eutectic solvents with a range of inorganic materials
Impact This is a multidisciplinary collaboration and we are publishing joint papers
Start Year 2013