PNEUMACRIT: Preterm Neonate / neonatal Embedded Universal Microelectronic wearable Acquisition For Cardio Respiratory Intensive Therapy

Lead Research Organisation: University of Cambridge
Department Name: Engineering

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

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Dimov I (2022) Adhesive cutaneous conducting polymer electrodes in Applied Physics Reviews

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Dimov IB (2022) Semiconducting Polymers for Neural Applications. in Chemical reviews

 
Description Our contribution to the PNEUMACRIT project involved designing organic electronic circuits and components for a impedance tomography imaging system. Towards that we developed and tested novel materials, designed and fabricated new devices. Work was carried out in extensive collaboration with the lab of Prof. Andreas Demosthenous (AD), in particular with PhD student Mrs. Farnaz Fahimi Hanzae.

The main focus of the project was developing an organic-electronic transistor-based amplifier for electrical impedance tomography. We fabricated organic electrochemical transistors (OECT) of varying parameters, which we supplied to the lab of AD, for the purpose of constructing a model to inform design of complex voltage amplifier circuits (Hanzaee et al., 2021) . After optimizing the design to a more suitable form factor for prototyping, and integrating with additional discrete components, we are currently preparing a manuscript describing differential amplifiers with voltage gain of ~5, based on OECTs.

We additionally established a collaboration with industry, Heraeus AG GmBH, through which we tested materials for self-adhering conductive polymer electrodes (Dimov et al., 2022). The materials showed adhesive properties similar to neonatal medical tape, suggesting their potential use in neonatal cutaneous electrophysiology. This publication was highlighted by the editor of Applied Physics Reviews)

Additionally, in order to make our devices easier to manufacture at scale, we explored different ways of depositing metal films at ambient conditions, to avoid the use of slow and costly high-vacuum procedures. We discovered a process to deposit gold tracks onto polymer substrates under ambient conditions. Currently, we are preparing to submit a manuscript on the subject (Dimov et al. 2023 - in preparation).

Lastly, we published an extensive review on conducting polymers for neural applications, in Chemical Reviews.
Exploitation Route Advances achieved in this project in the areas of
- new materials for cutaneous electrodes
- transistor architectures for wearable applications
will potentially have several applications. For example the wearable electrodes developed will be of use in other health monitoring scenarios, for example recording of heart, brain and muscle activity. These are applications that are being considered for at-home monitoring of the elderly and at-risk individuals. The transistor architectures are generic and can be used in implantables to amplify the weak signals obtained in neurotechnology applications, as well as for implants in plants and trees, which are being developed for precision agriculture. Finally, the internet-of-things is another area that will benefit fro advances in organic electronic circuitry.
Sectors Electronics,Environment,Healthcare

 
Description Invited talks at the MRS Spring Meeting, May 8-13, 2022 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Delivered two invited talks and several contributed (by group members) to a large and interdisciplinary audience interested in applications of novel materials
Year(s) Of Engagement Activity 2022
URL https://www.mrs.org/meetings-events/spring-meetings-exhibits/past-spring-meetings/2022-mrs-spring-me...
 
Description Keynote presentation at 18th International Conference on Nanosciences and Nanotechnologies 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Keynote presentation: "Technology for bioelectronic medicine", 18 International Conference on Nanosciences and Nanotechnologies (N&N), July 6-9, Thessaloniki, Greece (via teleconference due to COVID restrictions).
Year(s) Of Engagement Activity 2021
URL https://www.nanotexnology.com/index.php/nn
 
Description Keynote presentation at 3rd International Conference on Flexible Electronics 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Keynote presentation: "Technology for bioelectronic medicine", 3rd International Conference on Flexible Electronics (ICFE), Nov. 12-14, 2021, Hangzhou, China (via teleconference due to COVID restrictions).
Year(s) Of Engagement Activity 2021
 
Description Keynote presentation at Hellenic Conference on Solid-State Physics and Materials Science 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Gave the keynote presentation at national conference
Year(s) Of Engagement Activity 2022
URL https://fsk36.materials.uoc.gr/
 
Description Keyonote presentation at International Conference on Intelligent Wearable Systems in Hong Kong 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Gave keynote presentation in Hong Kong at conference on werable electronics attended by academic and industrial scientists from around the world
Year(s) Of Engagement Activity 2022
URL https://www.polyu.edu.hk/en/riiwear/news-and-events/events/2022/jun/iciws-2022/
 
Description Outreach Talk: Digitalize in Stockholm 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Outreach Talk: "Technology for bioelectronic medicine", Digitalize in Stockholm, Stockholm, Sweden, Oct. 21, 2021 (via teleconference due to COVID restrictions).
Year(s) Of Engagement Activity 2021
URL https://digitalizeinsthlm21.se/
 
Description Public Seminar on Bioelectronic Medicine, University of Linkoping, Sweden. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Public seminar on the occasion of award of honorary doctorate, reaching current members, alumni and steakholders of Linkoping University.
Year(s) Of Engagement Activity 2022
 
Description Public presentation at Cambridge Alumni Festival 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Gave talk on brain implants to Cambridge Alumni Festival
Year(s) Of Engagement Activity 2020
URL https://www.alumni.cam.ac.uk/festival/events/electronics-on-the-brain