Mother-infant interactions in high-risk autism siblings

Lead Research Organisation: University of Manchester
Department Name: Medical and Human Sciences

Abstract

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Publications

10 25 50
 
Description This work has been publicised widely, in the most part in the context of the use of the measure we developed in the evaluation of parent-mediated intervention. This intervention has been shown to benefit parent-infant interactions so has benefited those individuals who have taken part in the study. The work has been publicised in national newpapers and other news sources, as well as reported by autism charity websites and articles. The impact therefore is changing the way society thinks about the importance of parent-infant interaction in social and communicative development, even in what is considered an 'incurable' neurodevelopmental disorder; e.g. https://www.theguardian.com/science/2015/mar/26/can-parental-training-improve-the-course-of-autism https://spectrumnews.org/features/deep-dive/the-social-network-how-everyday-interactions-shape-autism/
First Year Of Impact 2015
Impact Types Societal

 
Title MACI Infant 
Description Manchester Assessment of Caregiver-Child Interaction: Infant Version This rating scale was developed for 3-15 month infants as an evaluative measure of global qualities of caregiver-infant interaction. 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2014 
Provided To Others? Yes  
Impact This has since been used to evaluate a clinical trial of a parent-mediated intervention for infants at risk of autism. We have further extended this into a Toddler version (MACI Toddler), making this measure highly suited for longitudinal measurement, and we have published a validation of the infant version in a normative sample (2016). The Toddler version will also now be used to evaluate a similar trial in an Australian at-risk autism sample. The MACI has also been used in other groups, such as mothers with depression and normative samples in relation to biological measures including fMRI, ERP, now fNIRS, and examined in relation to plasma oxytocin in healthy mothers. We have developed a full training package of the infant version and have started providing external trainings as there has been considerable interest in this kind of relatively simple measure. 
URL http://www.bbmh.manchester.ac.uk/maci/
 
Description Multicentre collaborative project 
Organisation Birkbeck, University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution This original project has led to extended discussions with 5 infancy autism risk projects worldwide, which we have developed to work together on a grant application to work on a longitudinal collaborative project on parent-child interaction in young children at risk of autism.
Collaborator Contribution They have implemented the parent-child interaction free play procedure in their standard protocol within their at-risk projects, and have started collating videotaped data, with our input for standardisation.
Impact So far, we have applied for a grant application together. Within the EU-AIMS network, we have also been involved in receiving researchers for exchange visits (COST Short-Term Scientific Mission) and have offered a training school, providing a taster training in the parent-child interaction measure that we developed from this project.
Start Year 2013
 
Description Multicentre collaborative project 
Organisation Karolinska Institute
Country Sweden 
Sector Academic/University 
PI Contribution This original project has led to extended discussions with 5 infancy autism risk projects worldwide, which we have developed to work together on a grant application to work on a longitudinal collaborative project on parent-child interaction in young children at risk of autism.
Collaborator Contribution They have implemented the parent-child interaction free play procedure in their standard protocol within their at-risk projects, and have started collating videotaped data, with our input for standardisation.
Impact So far, we have applied for a grant application together. Within the EU-AIMS network, we have also been involved in receiving researchers for exchange visits (COST Short-Term Scientific Mission) and have offered a training school, providing a taster training in the parent-child interaction measure that we developed from this project.
Start Year 2013
 
Description Multicentre collaborative project 
Organisation Radboud University Nijmegen
Department Donders Institute for Brain, Cognition and Behaviour
Country Netherlands 
Sector Academic/University 
PI Contribution This original project has led to extended discussions with 5 infancy autism risk projects worldwide, which we have developed to work together on a grant application to work on a longitudinal collaborative project on parent-child interaction in young children at risk of autism.
Collaborator Contribution They have implemented the parent-child interaction free play procedure in their standard protocol within their at-risk projects, and have started collating videotaped data, with our input for standardisation.
Impact So far, we have applied for a grant application together. Within the EU-AIMS network, we have also been involved in receiving researchers for exchange visits (COST Short-Term Scientific Mission) and have offered a training school, providing a taster training in the parent-child interaction measure that we developed from this project.
Start Year 2013
 
Description Multicentre collaborative project 
Organisation University of Ghent
Country Belgium 
Sector Academic/University 
PI Contribution This original project has led to extended discussions with 5 infancy autism risk projects worldwide, which we have developed to work together on a grant application to work on a longitudinal collaborative project on parent-child interaction in young children at risk of autism.
Collaborator Contribution They have implemented the parent-child interaction free play procedure in their standard protocol within their at-risk projects, and have started collating videotaped data, with our input for standardisation.
Impact So far, we have applied for a grant application together. Within the EU-AIMS network, we have also been involved in receiving researchers for exchange visits (COST Short-Term Scientific Mission) and have offered a training school, providing a taster training in the parent-child interaction measure that we developed from this project.
Start Year 2013
 
Description Multicentre collaborative project 
Organisation University of North Carolina at Chapel Hill
Country United States 
Sector Academic/University 
PI Contribution This original project has led to extended discussions with 5 infancy autism risk projects worldwide, which we have developed to work together on a grant application to work on a longitudinal collaborative project on parent-child interaction in young children at risk of autism.
Collaborator Contribution They have implemented the parent-child interaction free play procedure in their standard protocol within their at-risk projects, and have started collating videotaped data, with our input for standardisation.
Impact So far, we have applied for a grant application together. Within the EU-AIMS network, we have also been involved in receiving researchers for exchange visits (COST Short-Term Scientific Mission) and have offered a training school, providing a taster training in the parent-child interaction measure that we developed from this project.
Start Year 2013
 
Title Parent-mediated intervention for infants at risk of autism (iBASIS-VIPP) 
Description The original ESRC-funded project has helped contribute substantially to the development of this intervention as well as its evaluation. The intervention uses non-directive feedback via video recordings and working with caregivers to enhance sensitivity to their infant's cues and encourage positive social development. 
Type Preventative Intervention - Behavioural risk modification
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2010
Development Status Under active development/distribution
Clinical Trial? Yes
Impact The development of an adapted version of the measure for toddlers that was originally developed in the ESRC funded project. Also, the intervention is being replicated across 2 sites in Australia. 
URL http://www.isrctn.com/ISRCTN87373263