Malaria, Productivity and Access to Treatment: Experimental Evidence from Nigeria

Lead Research Organisation: Michigan State University
Department Name: Agricultural Economics

Abstract

The consequences of ill health for productivity and economic development are presumed to be severe yet the rigorous evidence base for such a linkage is small. Vector borne diseases such as malaria cause direct impacts on the health and indirect impacts on the productivity and income of workers. In previous work, we have estimated statistically significant and large average treatment effects on earnings, labor supply and productivity of a curative malaria treatment using 800 seasonal cane cutting workers at a large sugarcane plantation in Nigeria using a randomized design. To estimate treatment effects, we use individual worker productivity data, derived from the piece rate wage system, which provides data on daily individual worker output and labor supply. A mobile health clinic was established on the plantation and used an exogenously determined ordering of workers to test and treat workers throughout the sugarcane harvest season. Despite large average treatment effects, we estimate only small, but statistically significant intent to treat effects exclusively on labor supply. These results present an explanation for why firms do not provide more extensive testing and treatment for malaria. Due to the small intent to treat labor supply effects, it is likely to be more cost-effective for firms to hire more workers than invest in health services for workers. But the results also present a puzzle as to why workers do not take up preventative or curative treatment for malaria, while the potential gains are large. To better understand under what conditions workers will take up private treatment, we propose to extend our work by offering access to malaria testing and treatment at exogenously varied prices and estimate its effect on take-up and frequency of health care, and their effects on worker productivity. Collecting additional information on workers' social networks and subjective expectations of the risk of malaria infection will also increase the understanding of the determinants of demand for private health care and insurance against illness from malaria. The access to treatment intervention will be offered during the second part of the harvest season. In the first part of the harvest season the study will replicate and extend the previous approach by measuring the effect of treatment on both worker productivity and physical activity. This will provide us with a broader insight of the effect of malaria infection on physical activity in general, and allow us to draw careful inference regarding the potential effects of malaria treatment on other work activities. Workers will be informed at the beginning of the season that they get a free treatment in the first part of the season (randomly allocated) but will need to pay in the second part if they want further access. This combined approach strikes a balance between creating access to treatment for the workers, making sure they realize the benefits of treatment, and respecting real life budget constraints of health care provision.

Planned Impact

This research project will identify the causal mechanism between improved health - via the reduction of malarial episodes - and its impact on worker productivity. By simultaneously measuring its impact on worker activity, it will also develop a method to draw inference regarding the impact of malaria beyond the study context. Finally, by offering access to malaria treatment and insurance, the study will estimate the conditional demand for malaria treatment.

The research outcomes have three potential impacts: both on a larger literature in public health and labor economics and on the policy of malaria eradication internationally.

Regarding the first area of impact, the study will assess the causal effect of health on productivity. Existing work on this is still scarce as it has been difficult to identify due to the dual causality between health and productivity. This study would isolate a single pathway and can control for other potential confounding unobservable factors such as worker motivation, ability, previous health investments, disease or morbidity history, and genetic characteristics, because the distribution of these unobservable characteristics would be identical between the treatment and control groups.

In a second area of impact, the study would produce more detailed information on the potential benefits of malaria reduction or eradication as a development strategy. These effects are currently imprecisely understood because of the lack of rigorous studies that take into account the implications of unobservable plantation, household and individual characteristics. This study will advance policy understanding in this regard.

In a third area, the study will provide constructive advice and ways forward on how to provide access to treatment for agricultural workers. It will allow estimation of workers' willingness to pay and hence provide concrete ways forward on how to offer access to malaria treatment and insurance in rural areas, which may help remove constraints on growth in agricultural productivity. By incorporating detailed social network information for each worker, a potentially important determinant of take-up of malaria testing and treatment will be formally integrated into the analysis.

The co-leadership and active involvement of the Centre for Research and Development at the Federal University of Technlogy at Yola, warrants that the findings will feed into both the Nigerian national academic and policy debates and maximizes its impact on policymaking, as the Centre has an exemplary track record in this area and its advice has been well absorbed by policymakers.

The project will also have an impact on the further development of the Centre's capacity with staff and students actively involved. We envisage that both masters and undergraduate students of the Parasite and Tropical Health Research unit, as well as laboratory science students will be part of the implementation team and participate in the analysis.

The proposal fits very well with the country malaria eradication strategy. The implementation of the on-going research was coordinated with the National Malaria Control Program within the Ministry of Health through a number of meetings, and was actively supported by the Director (then Dr Sofola).

Prof. Oladele Akogun is an integral part of this research. As Director of the Centre for Research and Development at the Federal University of Technology at Yola, Nigeria, he also actively engages a community of senior and junior researchers, as well as students in the research. Through the pilot, the project has already built capacity by actively involving masters, undergraduate and laboratory students in the implementation and analysis.

The research has also engaged Nigeria APSF, which is IFPRI's Nigeria Country Program which prefunded an initial feasibility study. There are also close contacts with The World Bank, USAID, DFID, and malaria experts in UK.
 
Description Project summary
The consequences of ill health for productivity and economic development are presumed to be severe yet the rigorous evidence base for such a linkage is small. In previous work, statistically significant and large intent to treat effects were estimated on earnings, labor supply and productivity of a curative malaria treatment at a large sugarcane plantation in Nigeria. A mobile health clinic was established on the plantation and used an exogenously determined ordering of workers to test and treat workers. Despite large treatment effects, we find that workers have low rates of seeking curative and preventative treatments. To better understand this puzzle, this study offers access to malaria treatment and insurance at exogenously varied prices to estimate its effect on take-up and frequency of health care. In another phase, the study also measured the effect of treatment on both worker productivity and physical activity. This will allow estimation of the effects of malaria on physical activity in general, and allow us to extrapolate our findings in this context to other physical occupations in endemic areas.

Research activities
The field work was fully implemented, but the timing was adapted. Severe flooding in the study area forced us to postpone fieldwork slightly and re-arrange research plans, as explained in the progress report. We requested and received a one year extension of our grant to enable us to deliver the research originally proposed with limited tradeoffs in the design. The new design kept the same research questions and interventions, but shifted them in time, respecting the order of treatments, but also taking into account importance of seasonality, potential measurement error over time, comparison with previous data and budget limits. The first part of the study remained the same, but took place in the second part of the harvest season (January-April 2013). The second part of the study, focusing on willingness to pay for private treatment and insurance against malaria, took place in the second part of the next harvest season, namely January-April 2014. This was at the same time in the harvest season as originally planned, but one year later. Having completed the field work successfully we are still in the progress of analysing the data.


Research findings
The preliminary findings for the two main research questions are as follows:
1. Alternative Productivity Measures and Replication Results: This study extends previous work on the impact of a malaria testing and treatment program by replicating a study design previously reported in Akogun et al. (2014). We find similar earnings effects of the malaria testing and treatment program on workers who tested positive (7 percent increase in earnings due to treatment) as in previous rounds, yet the statistical precision of these estimates suffers due to an unforeseen closure on the plantation during the study period which limited the number of worker-week observations. During the same study period, alternative measures of productivity using physical activity monitoring were collected for a worker subsample. Treatment effects on the treated using measures of physical activity indicated that workers daily average time sedentary reduced by forty minutes and time in light physical activity and average physical activity levels increased for the average treated worker by 31 and 32 minutes, respectively. A composite measure of physical activity is also statistically significant at the 5% level despite the reduced sample size. These results suggest that alternative productivity measures such as physical activity illustrate an important mechanism through which malaria treatment affects labor productivity and earnings.

2. Provision of Malaria Insurance: Our data confirms that workers' willingness to pay for the type of health insurance on offer is modest, but also shows substantial variation. Demand is price sensitive with an estimated elasticity of -0.25. Workers with more experience with and exposure to malaria health care tend to have higher willingness to pay, as do workers who have more accurate knowledge of the treatment of malaria (but not about symptoms or prevention). Those with higher general trust are also willing to pay more. We find little evidence for workers' risk preferences playing a role. For those who gained access to the insurance, we investigate the correlates of use of the service, and find, that apart from exposure and past experience, education, trust and self-assessed health also play a role. We then estimate the effect of health insurance on worker productivity, using the price draw as an instrument, and find that especially those with low willingness to pay benefit considerably from access to insurance, as it increases their income with roughly 10%, primarily through increases in daily productivity. Preliminary findings also indicate that for those who have gained access to the health insurance, use of the health care covered has strong effects on income, in particular through its effects on labor supply, but not productivity

Outputs
We developed the following 5 sets of outputs: (i) dissemination events, feedback meetings and media, (ii) draft papers, (iii) data and documentation, (iv) further data analysis and use by students and researchers
1. Dissemination events
? A conference "Workplace Based Malaria Treatment Programme: Evidence from Nigeria" was organised in Abuja on 25 June 2014. Its aim was to present preliminary results and receive further feedback from national malaria experts, the plantation, and users of the research. The conference was well attended by 19 people, including representatives from The National Malaria Control Programme at the Federal Ministry of Health, The Ministry of Health of Adamawe State, The Malaria Consortium (a national consortium that brings together experts working on malaria in Nigeria), Ministry of Agriculture, The World Bank, and various journalists. Other invited parties sent their apologies.
? The conference was accompanied by three policy notes summarising preliminary findings
? The conference resulted in two articles in national newspapers in Nigeria, namely the Nigeria Sunrise (7 July 2014) and the Daily Independent Lagos (17 July 2014).
? The conference was also linked to a blog 'How malaria testing can get more people back into work' at the conversation (https://theconversation.com/how-malaria-testing-can-get-more-people-back-into-work-32067)
? We had several feedback meetings with the plantation management, who has shown and active interest to continue and extend this work.
? Dissemination of the research include a range of presentations

2. Draft papers
Based on the existing data analysis, two draft papers have been written, containing the main preliminary findings addressing the two research questions.
? Agricultural Worker Productivity and Malaria: Alternative Productivity Measures using Physical Activity
? Agricultural workers' willingness to pay for malaria insurance at the workplace. Experimental evidence from Nigeria.


3. Data and documentation
Data and documentation will be completed after finishing the analysis.

4. Further data analysis and use by students and researchers

The existing data was further analysed by two students who choose this topic for their dissertation for the Masters of Science in Development Economics at the University of East Anglia; both were supervised by one of the PIs.
? Alix Clark, 2014, Alcohol Consumption and Agrarian Labour Outcomes in Rural Nigeria: A study of sugarcane cutters. The results show alcohol consumption has a significant negative association with earnings as a consequence of its negative association with productivity. It also highlights the moderating effect of religion and ethnicity among these workers. Analysis of payday alcohol consumption suggests that heavy episodic drinking is negatively associated to labour supply the following day.
? Alasdair Makintosh, 2014, The Effect of Nutrition on Productivity and Morbidity on Nigerian Sugarcane Cutters. This paper investigates the effect of nutrition on labour outcomes, more specifically, the non-linear effect of changes in Body Mass Index on labour productivity and morbidity. The study finds that although nutrition has a negligible effect on the productivity of workers within this sample, a significant and robust relationship exists between nutrition and morbidity.
? Ashesh Prasann, who has been a RA on this project, is further analysing the data as part of his PhD dissertation at MSU, and is supervised by one of the PIs. He is a co-author on the first output paper for this grant and will develop one other extension using the data for his PhD dissertation
? Sani Njobdi, who has been a field manager for this study, is exploring to analyse the data as part of a PhD dissertation at Modibbo Adama University of Technology, supervised by the one of the PIs
Exploitation Route Our results have broad implications for emerging research literature on health insurance and service delivery in developing countries. These results also underscore the importance of understanding mechanisms through which we presume programs have effects on earnings. By measuring physical activity, we trace the mechanism through which we presume curative malaria treatments affect worker productivity. This can be taken forward in future work by encouraging alternative measures of productivity measurement.

More specifically the study has 4 knowledge contributions on which future work is expected to build: First, new methods allow estimation of causal effects of health on worker income. Existing work suffers from shortcomings, including omitted variables, simultaneity, reverse causality and poor measurement of ill health and productivity. This study provides a way to address these. A second innovation is the measurement of physical activity, and its identification as a pathway through which treatment works; this also allows inference for other occupations. The World Bank has shown an interest in adopting this method. A third innovation is the offer of a workplace based insurance and study of its impact. There is very limited understanding of the failure in demand for health care and insurance in rural areas, let alone its impact on income. Finally, the results highlight the usefulness of a workplace based approach and involvement of the private sector. National Malaria programme has invited us to further discuss. The plantation has also communicated a strong interest in sustained collaboration.
Sectors Agriculture, Food and Drink,Healthcare

URL http://theconversation.com/how-malaria-testing-can-get-more-people-back-into-work-32067
 
Description To reach national policymakers and malaria experts, the business community, NGO's and other users of the research, a conference on "Workplace Based Malaria Treatment Programme" was organised in Abuja on 25 June 2014. The purpose of this conference was to communicate and get feedback on final results from the first phase and preliminary results of the second phase of the research. The conference was well attended, including representatives from The National Malaria Control Programme at the Federal Ministry of Health, The Ministry of Health of Adamawa State, The Malaria Consortium (which brings together experts working on malaria in Nigeria), Ministry of Agriculture, The World Bank, and various journalists. The conference was accompanied by three policy notes summarising findings. The conference resulted in two press articles in national newspapers in Nigeria. The results were also discussed in two blogs, one oriented towards the development community, and one towards the general public. Several feedback meetings were held with the plantation management, who has shown and active interest to continue and extend this work, and future extensions are currently under discussion. In addition to stakeholder conferences and meetings with the plantation management, results were presented to the Chief Economist (DFID) in February 2015, a multidisciplinary panel at the upcoming 2016 American Society of Tropical Medicine and Hygiene which includes policymakers and nongovernmental organizations active in malaria policy, and two presentations in collaboration with the World Bank and Nigerian stakeholders in Washington DC and Abuja.
First Year Of Impact 2014
Sector Agriculture, Food and Drink,Healthcare
Impact Types Policy & public services

 
Description DEVCo Surplus Grant
Amount £5,000 (GBP)
Organisation University of East Anglia 
Sector Academic/University
Country United Kingdom
Start 05/2014 
End 05/2015
 
Description Internal Research Grant
Amount $8,000 (USD)
Organisation Michigan State University 
Sector Academic/University
Country United States
Start 03/2013 
End 03/2014
 
Description funding for dissemination of research
Amount £5,000 (GBP)
Organisation Overseas Development Institute (ODI) 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2014 
End 09/2014
 
Title Malaria and Labor Productivity Datasets 
Description This is the set of data collected in 2013 and 2014 as described in our two working papers. 
Type Of Material Database/Collection of data 
Year Produced 2014 
Provided To Others? Yes  
Impact We have just finalized the research databases to produce are own research papers and are beginning to share the data with graduate students. 
 
Description Dissemination of research 
Organisation Overseas Development Institute (ODI)
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution the PIs concentrated on writing and revising the text and presentation for large audiences.
Collaborator Contribution Close cooperation with ODI has helped to disseminate our findings in a blog, as well as through participation of conference. ODI has helped with communication, providing feedback on written materials, and liaising the PIs with blog hosts;
Impact blog at the conversation
Start Year 2014
 
Description Local implementer 
Organisation Common Heritage Foundation
Country Nigeria 
Sector Charity/Non Profit 
PI Contribution The PIs helped build capacity and passed on expertise regarding implementing the research.
Collaborator Contribution The Common Heritage Foundation did a very good job implementing the research, and work in team with the PIs, implementing the research in a professional manner, following high ethical standards and respecting the agreed protocols. The partnership will lead to further planned joint research.
Impact The policy notes were prepared in collaboration with the Common Heritage Foundation
Start Year 2012
 
Description Plantation management and firm 
Organisation Dana-Farber Cancer Institute
Department Department of Radiation Oncology
Country United States 
Sector Hospitals 
PI Contribution We have developed a strong partnership with the plantation management and owners of the firm. We held frequent liaison, planning and feedback meetings with the plantation management. A committee was formed with representatives of the plantation and the researchers to oversee all activities of the field work. Further contact was established with the firms' head quarter in Lagos, and a follow up meeting to discuss future activities has been planned. In the collaboration the researchers generated unique insights into the health and productivity of the workers, which are of use to the plantation.
Collaborator Contribution The partnership between the researchers and the plantation springs from the complementary efforts by both parties. the plantation supported and allowed the organization of the field research, including many suggestions regarding its implementation.
Impact Three policy notes were produced to summarise the most relevant insights of the research for the plantation.
Start Year 2010
 
Description Academic Presentations 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Our research was presented in part or as part of a more general presentation for a range of academic and policy audiences

Seminar and invited presentations:
University of Bordeaux, June 2016: key note speaker to Development Conference
York University, October 2016
Maastricht UNU, January 2017

University of California, Davis, April 2015
Nottingham School of Economics, March 2015 +
Wageningen University, Development Conference, March 2015
Institute for Fiscal Studies, March 2015 +
Center for Behavioural and Experimental Social Science, University of East Anglia, Feb 2015
University of Illinois: Urbana-Champaign, October 2014
Purdue University, April 2014
University of Minnesota, February 2014
University of Kent, February 2014 +
University of Manchester, February 2014+
Medical School, University of East Anglia, Dec 2013+
DePaul University, November 2013
Michigan State University, October 2013
further invitations from the Universities of Bristol, Bergen, Oslo, Antwerp, KULeuven, Namur had to be declined due to a lack of time.

Conference presentations:
CERGEI, SEEDEC, December 2015
JPAL, Paris School of Economics, September 2015+
Western Economic Association, July 2015
EDePO Institute for Fiscal Studies 'Improving Productivity in Developing Countries' Conference, July 2015
Network for Integrated Behavioural Sciences, Nottingham, April 2015
Center for the Study of African Economies, University of Oxford, March 2015
NEUDC, Boston University, November 2014+
Agricultural and Applied Economics Association Meetings, Frontier Topics in International Agricultural Development, International Section Track, July 2014
Royal Economic Society, University of Manchester, April 2014+
Year(s) Of Engagement Activity 2014,2015,2016,2017
 
Description Blog post at the Conversation 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact We provided a non-technical summary of our research with assistance from ODI to disseminate some of our early research findings.

We are not aware of the number of page hits at the current time which would be one way to measure the effectiveness of the blog post.
Year(s) Of Engagement Activity 2014
URL http://theconversation.com/how-malaria-testing-can-get-more-people-back-into-work-32067
 
Description Policy Dissemination Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Type Of Presentation paper presentation
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact We organized a dissemination conference in Abuja Nigeria in July 2014 with participation from Ministry of Health and Ministry of Agriculture officials from the Government of Nigeria as well as local researchers and students to comment on the malaria and labor productivity research program. Research papers and policy briefs were presented.

After the conference, national newspapers carried stories communicating the research results to the general public. There was engagement with the ownership of the sugarcane plantation through their philanthropic foundation to potential participate more formally in this work going forward.
Year(s) Of Engagement Activity 2014
 
Description Policy Notes 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact We wrote three policy notes which accompanied the workshop / conference we organised and which summarised key findings:
1. Akogun O., A. Adesina, A. Dillon, J. Friedman, S. Njobdi, A. Prasann, P. Serneels, 2014, Workplace-based Malaria Treatment Program in Nigeria Demonstrates Significant Effects on Earnings, Labor Supply and Productivity of Agricultural Workers
2. Akogun O., A. Adesina, A. Dillon, J. Friedman, S. Njobdi, A. Prasann, P. Serneels, 2014, Effects of Malaria Treatment on Fitness and Activity among Agricultural Workers
3. Akogun O., A. Adesina, A. Dillon, J. Friedman, S. Njobdi, A. Prasann, P. Serneels, 2014, Agricultural Workers' Willingness to Pay for Access to Malaria Testing and Treatment
Year(s) Of Engagement Activity 2014
 
Description Policy Presentations 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact We presented the results as a whole or as part of a larger presentation at
Institute for Fiscal Studies, March 2015
JPAL, Paris School of Economics, September 2015
DFID, Chief Economist Office, London, February 2015
Year(s) Of Engagement Activity 2015
 
Description Press 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact The workshop / conference organised in Abuja was accompanied by press interviews and resulted in two press articles in national newspapers in Nigeria, namely the Nigeria Sunrise (Abuja, 7 July 2014) and the Daily Independent (Lagos, 17 July 2014).
Year(s) Of Engagement Activity 2014
 
Description The Conversation Blog post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact We wrote a blog that was published at The Conversation with help from ODI.
Year(s) Of Engagement Activity 2017
URL https://theconversation.com/malaria-testing-and-treatment-increases-worker-wellness-as-well-as-effor...
 
Description World Bank conference with Nigerian Ministry of Health 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact The World Bank organized a dissemination event with the Ministry of Health, Nigeria where the study results were discussed with representatives of the Ministry as well as NGO, academic, and international organization professionals.
Year(s) Of Engagement Activity 2017