Bacterial infection and morphogenesis in the nematode C. elegans

Lead Research Organisation: University of Oxford
Department Name: Biochemistry


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Description MRC Programme Grant
Amount £1,866,841 (GBP)
Funding ID MR/J001309/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2012 
End 03/2017
Title Microarray data on nematode infection 
Description Microarray data on the response of the nematode C. elegans to infection by the pathogen Microbacterium nematophilum 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2006 
Provided To Others? Yes  
Impact Identification of nematode C-type lectin genes as a major class of immune-associated genes in C. elegans. 
Title Nematode mutant strains 
Description Characterized mutant strains of the nematode C. elegans 
Type Of Material Biological samples 
Year Produced 2006 
Provided To Others? Yes  
Impact Analysis of C. elegans responses to Yersinia pestis, causative agent of plague 
Description cholinergic neurogenetics 
Organisation Harvard University
Department Harvard Medical School
Country United States 
Sector Academic/University 
PI Contribution Genetic data, mutant strains
Collaborator Contribution Molecular and physiological data
Impact PMID: 16604067
Description nematode collagen research 
Organisation University of Glasgow
Department School of Life Sciences Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Cell biological and genetic analysis of nematode collagen assembly
Collaborator Contribution Provision of antibodies
Impact PMID: 16452136
Description telomerase 
Organisation University of North Carolina at Chapel Hill
Country United States 
Sector Academic/University 
PI Contribution Collaboration on genetic and phenotypic analyses
Collaborator Contribution Investigation of telomere biology and mutator activity in the nematode C. elegans
Impact PMID: 16477310 PMID: 16951081
Description Art and Science in Oxford 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact I organized a public meeting in Jan 2006, on Art and Science in Oxford, in relation to the Salt Bridges Arts Programme for the New Biochemistry building. This included description of my research.

Increased awareness of biochemical and medical research, and its relationship to the arts. Increased funding for art/science projects.
Year(s) Of Engagement Activity 2006