the functional integration of elementary calcium signals in an excitable secretory cell

Lead Research Organisation: Newcastle University
Department Name: Inst for Cell and Molecular Biosciences

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
 
Description BBSRC Quota DTG Studentship
Amount £70,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 09/2007 
End 09/2011
 
Description MRC PhD Studentship
Amount £35,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2008 
End 09/2013
 
Description MRC Research Grant
Amount £400,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2007 
End 08/2010
 
Description PhD studentship/Randerson Foundation
Amount £80,000 (GBP)
Organisation Newcastle University 
Department Randerson Foundation
Sector Charity/Non Profit
Country United Kingdom
Start 09/2011 
End 09/2015
 
Description metal binding 
Organisation Newcastle University
Department Institute for Cell and Molecular Biosciences
Country United Kingdom 
Sector Academic/University 
PI Contribution Experimental technique (confocal microscopy) and intellectual input.
Collaborator Contribution Expertise in metal chelation and bacterial biochemistry
Impact PMID: 18948958
Start Year 2007
 
Description patch-clamp 
Organisation University of Washington
Department Department of Pharmacology
Country United States 
Sector Academic/University 
PI Contribution Expertise in calcium signalling in electrically excitable cells and training of staff
Collaborator Contribution provision of technical expertise and equipment
Impact PMID: 16806464
 
Description retinoids 
Organisation Newcastle University
Department Northern Institute for Cancer Research Newcastle
Country United Kingdom 
Sector Academic/University 
PI Contribution Expertise in calcium signalling mechanisms in neuronal cells and confocal microscopy
Collaborator Contribution Expertise in retinoid-induced differentiation of cells
Impact Several publications, notably PMID 16914200. See also entry for G0000190 PhD studentship funded
 
Description retinoids 
Organisation Newcastle University
Department Northern Institute for Cancer Research Newcastle
Country United Kingdom 
Sector Academic/University 
PI Contribution Expertise in calcium signalling in neuronal cells
Collaborator Contribution Expertise in retinoid-induced differentiation of cells
Impact PMID:15673285 PMID:16095688 PMID:16914200 PhD studentship funded
 
Description ryanodine 
Organisation University of Oxford
Department Department of Physiology, Anatomy and Genetics
Country United Kingdom 
Sector Academic/University 
PI Contribution Expertise in mammalian ryanodine receptor signalling mechanisms
Collaborator Contribution MRC Functional Genomics Unit: Expertise in insect signalling mechanisms
Impact PMID: 18696132
Start Year 2007
 
Description urology 
Organisation Beatson Institute for Cancer Research
Country United Kingdom 
Sector Academic/University 
PI Contribution measurements of changes in concentration of intracellular Ca2+
Collaborator Contribution increased understanding of mechanisms of smooth muscle cell differentiation
Impact PMID: 20546875 multi-disciplinary: molecular and cellular techniques
Start Year 2006
 
Description Institute booklet 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Institute research booklet, aimed at the public

Unknown
Year(s) Of Engagement Activity 2007,2008,2009,2010,2011,2012,2013,2014,2015,2016,2017,2018,2019
 
Description School Open Day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? Yes
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Public Open Days - c5 per year. for prospective undergraduate and postgraduate students, and their parents.

Increase in number of 'Unconditional/Conditional Firm' UCAS applicants to School (Department). Info: Board of Studies, School of Biomedical Sciences
Year(s) Of Engagement Activity 2007,2008,2009,2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020
 
Description School children - Sunderland 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Field questions on email from primary school children in Sunderland who wanted to talk to a 'real scientist'.

The children were very pleased.
Year(s) Of Engagement Activity 2007,2008,2009
 
Description School pupils - work experience 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact School pupils work in the lab during vacation for work experience (ongoing dates)

increase in requests for information on career pathways to become a researcher
Year(s) Of Engagement Activity 2009,2010,2011,2012,2013,2014,2015,2016
 
Description Website - public 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact General University website

Unkown
Year(s) Of Engagement Activity 2008,2009,2010,2011,2012,2013,2014,2015,2016
 
Description Website - specialised 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Personal and Institute websites

Contact from prospective PhD students and post-doctoral researchers
Year(s) Of Engagement Activity 2007,2008,2009,2010,2011,2012,2013,2014,2015,2016