Functional Analysis of Lipid Rafts in Cell Signalling

Lead Research Organisation: Imperial College London
Department Name: Life Sciences

Abstract

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Publications

10 25 50
 
Description MRC Project Grant
Amount £500,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2008 
End 12/2010
 
Description MRC Project Grant
Amount £217,000 (GBP)
Funding ID G0400710 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 02/2005 
End 01/2008
 
Title Novel microscopy approaches 
Description Novel microscopy approaches to studying cell membrane organisation were developed with P. French, M. Neil and C. Dunsby. 
Type Of Material Technology assay or reagent 
Year Produced 2010 
Provided To Others? Yes  
Impact Publications PMID 16617080; 17728161; 19550853; 19343675 
URL http://europepmc.org/abstract/MED/16617080
 
Description Collaboration with D.C. Barral on endocytosis of CD1 and MHC proteins 
Organisation Harvard University
Department Harvard Medical School
Country United States 
Sector Academic/University 
PI Contribution We provided expertise on membrane microdomain analysis
Collaborator Contribution They provided cell systems and analysis of endocytosis of CD1 and MHC proteins
Impact Publication PMID: 18564371
 
Description Collaboration with E. Jury and T. Butters on T cell glycolipids and membrane domains 
Organisation University College London
Department Division of Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution We provided extertise on T cell membrane domains
Collaborator Contribution T. Butters - expertise on glycolipids E. Jury - expertise on T cell function and role in SLE
Impact PMID: 21307290
Start Year 2007
 
Description Collaboration with E. Jury and T. Butters on T cell glycolipids and membrane domains 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution We provided extertise on T cell membrane domains
Collaborator Contribution T. Butters - expertise on glycolipids E. Jury - expertise on T cell function and role in SLE
Impact PMID: 21307290
Start Year 2007
 
Description Collaboration with M. Seabra on post-translational modification of Rab proteins 
Organisation Imperial College London
Department Section of Molecular Medicine (MM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Expertise on post-translational modifications of proteins
Collaborator Contribution Cell systems and knowledge of Rab proteins
Impact Publication PMID: 17114793
 
Description Collaboration with T. Schmidt on intracellular diffusion of lipid modified proteins 
Organisation Leiden University
Country Netherlands 
Sector Academic/University 
PI Contribution Expertise on membrane microdomains and acylated proteins.
Collaborator Contribution They provided the biophysical methodology.
Impact Publication PMID 16920696
 
Description collaboration on RET with I. Plaza-Menacho and C. Isacke 
Organisation Canadian Institutes of Health Research
Department Institute of Cancer Research
Country Canada 
Sector Public 
PI Contribution collaboration with I. Plaza-Menacho and C. Isacke on RET signalling in cancer; we provided signalling expertise.
Collaborator Contribution collaboration with I. Plaza-Menacho and C. Isacke on RET signalling in cancer; they provided cell systems and signalling expertise
Impact Publications PMID: 17664273; 17209045; 21454698