Preclinical studies of cancer chemopreventive agents

Lead Research Organisation: University of Leicester
Department Name: Centre for Mechanisms of Human Toxicity


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.




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Bond JA (2007) Cytotoxic action of phorbol esters on human pancreatic cancer cells. in International journal of cancer

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Boocock DJ (2007) Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

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Cai H (2009) Flavones as colorectal cancer chemopreventive agents--phenol-o-methylation enhances efficacy. in Cancer prevention research (Philadelphia, Pa.)

Description CRUK Programme Grant
Amount £800,000 (GBP)
Organisation Cancer Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2006 
End 08/2011
Title pentamethoxyflavone 
Description colorectal cancer chemoprevention 
Type Preventative Intervention - Nutrition and Chemoprevention
Current Stage Of Development Initial development
Year Development Stage Completed 2006
Development Status Actively seeking support
Impact dont know yet 
Description Cancer Prevention 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Primary Audience Public/other audiences
Results and Impact Many questions at talks

Invitation to give further lectures
Year(s) Of Engagement Activity 2006,2007