Directed differentation of neural stem cells to hypothalamic neuronal fates

Lead Research Organisation: University of Sheffield
Department Name: Biomedical Science


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Description Research traning in es methodologies
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Title Model of hypothalamic development 
Description In vitro explant culture and associated cell line as tool for hypothalamic cell development 
Type Of Material Model of mechanisms or symptoms - in vitro 
Year Produced 2007 
Provided To Others? Yes  
Impact Working up cell line for knowledge transfer purposes 
Description Directed diferentiation of mouse es cells to motor neuron fates: analysis in SOD mutant mice 
Organisation University of Sheffield
Country United Kingdom 
Sector Academic/University 
PI Contribution Taught PhD student how to culture and differentiate mouse es cells
Collaborator Contribution Link to clinical academic neuroscience
Impact PhD thesis. manuscript in preparation. Multi-disciplinary collaboration between basic and clinican scientist
Start Year 2007
Description Regional Science Learning Centres and Schools 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach Local
Primary Audience Schools
Results and Impact Discussion of use of animal model systems in stem cell research

Increasing requests for local schools talks
Year(s) Of Engagement Activity 2006,2007,2008