Germline variation in DNA repair genes as determinants of presenting features and outcome in bowel cancer patients from
Lead Research Organisation:
University of Oxford
Department Name: Physiology Anatomy and Genetics
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
COGENT Study
(2008)
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.
in Nature genetics
Houlston RS
(2010)
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.
in Nature genetics
Jaeger E
(2008)
Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk.
in Nature genetics
Pittman AM
(2008)
Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer.
in Human molecular genetics
Spain S
(2009)
Colorectal Cancer Risk Is Not Associated with Increased Levels of Homozygosity in a Population from the United Kingdom
in Cancer Research
Tomlinson IP
(2011)
Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.
in PLoS genetics
Tomlinson IP
(2008)
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.
in Nature genetics
| Description | Colorectal cancer GWAS |
| Organisation | Institute of Cancer Research UK |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Cases and genotypes, data analysis |
| Collaborator Contribution | Similar to mine: supply of samples and genome-wide SNP data, with data analysis |
| Impact | PMID: 19011631 PMID: 22878375 PMID: 22634755 PMID: 22490517 PMID: 22294770 PMID: 21655089 PMID: 20972440 |
| Description | Colorectal cancer GWAS |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Human Genetics Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Cases and genotypes, data analysis |
| Collaborator Contribution | Similar to mine: supply of samples and genome-wide SNP data, with data analysis |
| Impact | PMID: 19011631 PMID: 22878375 PMID: 22634755 PMID: 22490517 PMID: 22294770 PMID: 21655089 PMID: 20972440 |