Proteomic Analysis of the Function of Nuclear SUMO Modification
Lead Research Organisation:
University of Dundee
Department Name: Unlisted
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
People |
ORCID iD |
| Angus Iain Lamond (Principal Investigator) |
Publications
Dellago H
(2011)
Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing.
in The Biochemical journal
Drakou CE
(2012)
hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: structural and functional studies.
in Proteins
Malekkou A
(2010)
The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition.
in FEBS letters
Matic I
(2008)
In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy.
in Molecular & cellular proteomics : MCP
Ono M
(2011)
Identification of human miRNA precursors that resemble box C/D snoRNAs.
in Nucleic acids research
Pelisch F
(2010)
The serine/arginine-rich protein SF2/ASF regulates protein sumoylation.
in Proceedings of the National Academy of Sciences of the United States of America
Schmitz MH
(2010)
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.
in Nature cell biology
Ten Have S
(2011)
Mass spectrometry-based immuno-precipitation proteomics - the user's guide.
in Proteomics
Vertegaal AC
(2004)
A proteomic study of SUMO-2 target proteins.
in The Journal of biological chemistry
Vertegaal AC
(2006)
Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics.
in Molecular & cellular proteomics : MCP
Von Kriegsheim A
(2009)
Cell fate decisions are specified by the dynamic ERK interactome.
in Nature cell biology
Westman BJ
(2011)
A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomics.
in Nucleus (Austin, Tex.)
Westman BJ
(2010)
A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58.
in Molecular cell
| Description | RASOR |
| Organisation | Beatson Institute for Cancer Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Joint project with Edinbugh and Glasgow Universities. |
| Collaborator Contribution | N/A |
| Impact | Publications: PubMed ID 18936248 PubMed ID 19935650 |
| Start Year | 2006 |
| Description | co-author Jens Andersen |
| Organisation | University of Southern Denmark |
| Country | Denmark |
| Sector | Academic/University |
| PI Contribution | Publication |
| Collaborator Contribution | co-author |
| Impact | PMID: 16381850 PMID: 17000644 PMID: 17446074 PMID: 22311636 |
| Description | co-author Matthias Mann |
| Organisation | Max Planck Society |
| Department | Max Planck Institute of Biochemistry |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Publication |
| Collaborator Contribution | co-author |
| Impact | PMID: 16381850 PMID: 16492807 PMID: 17000644 PMID: 17446074 PMID: 17938407 PMID: 22311636 |
| Description | co-author Ron Hay |
| Organisation | Wellcome Trust |
| Department | Wellcome Trust Centre for Gene Regulation and Expression |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Publications |
| Collaborator Contribution | co-authors |
| Impact | Publications - 15175327 / 17000644 / 17938407 (Pubmed) |
| Company Name | Dundee Cell Products |
| Description | Dundee Cell Products (DCP) is a spin out company of University of Dundee of which Angus I Lamond is a co-founder. http://www.dundeecellproducts.com/ ; http://www.dundeecellproducts.com |
| Year Established | 2006 |
| Impact | 1. Dundee Cell Products has successfully commercialised SILAC quantitative proteomics technology to academic and commercial customers. It has carried out SILAC analysis for customers in about six universities and recently gained a service contract with one of the world's largest pharmaceutical companies to apply this technology in their drug discovery and development process. The company has also developed various SILAC ready-to-use tissue culture media that facilitate the culture of cell lines for subsequent quantitative proteomics analysis. These special SILAC media have gained customers all over Europe and in North America. 2. Since spinout, the company has commercialised life sciences research reagents including antibodies, recombinant proteins, DNA clones, stable cell lines, etc., many of which have been developed or licensed from Universities/academic institutions. 3. The company has created new jobs by employing five highly skilled staff (3 post-doctoral, two undergraduates). It also provides part-time work to two contractors (bookkeeper and accountant), work to local businesses and outsources some work to the University of Dundee thus providing extra revenue to the institution. |
| Website | http://www.dundeecellproducts.com/ |
| Description | Invited Seminar Speaker |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Participants in your research and patient groups |
| Results and Impact | Presentations of results Regularly invited as a seminar speaker |
| Year(s) Of Engagement Activity | 2006,2007,2008,2009,2010,2011,2012,2013 |
| Description | School Visit - Fife |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Presentation of research to school children Positive feedback from schools and being invited back |
| Year(s) Of Engagement Activity | 2006,2007,2008,2009,2016 |