Proteomic Analysis of the Function of Nuclear SUMO Modification

Lead Research Organisation: University of Dundee
Department Name: Unlisted


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.


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Pelisch F (2010) The serine/arginine-rich protein SF2/ASF regulates protein sumoylation. in Proceedings of the National Academy of Sciences of the United States of America

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Vertegaal AC (2004) A proteomic study of SUMO-2 target proteins. in The Journal of biological chemistry

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Von Kriegsheim A (2009) Cell fate decisions are specified by the dynamic ERK interactome. in Nature cell biology

Description RASOR 
Organisation Beatson Institute for Cancer Research
Country United Kingdom 
Sector Academic/University 
PI Contribution Joint project with Edinbugh and Glasgow Universities.
Collaborator Contribution N/A
Impact Publications: PubMed ID 18936248 PubMed ID 19935650
Start Year 2006
Description co-author Jens Andersen 
Organisation University of Southern Denmark
Country Denmark 
Sector Academic/University 
PI Contribution Publication
Collaborator Contribution co-author
Impact PMID: 16381850 PMID: 17000644 PMID: 17446074 PMID: 22311636
Description co-author Matthias Mann 
Organisation Max Planck Society
Department Max Planck Institute of Biochemistry
Country Germany 
Sector Academic/University 
PI Contribution Publication
Collaborator Contribution co-author
Impact PMID: 16381850 PMID: 16492807 PMID: 17000644 PMID: 17446074 PMID: 17938407 PMID: 22311636
Description co-author Ron Hay 
Organisation Wellcome Trust
Department Wellcome Trust Centre for Gene Regulation and Expression
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Publications
Collaborator Contribution co-authors
Impact Publications - 15175327 / 17000644 / 17938407 (Pubmed)
Company Name Dundee Cell Products 
Description Dundee Cell Products (DCP) is a spin out company of University of Dundee of which Angus I Lamond is a co-founder. ; 
Year Established 2006 
Impact 1. Dundee Cell Products has successfully commercialised SILAC quantitative proteomics technology to academic and commercial customers. It has carried out SILAC analysis for customers in about six universities and recently gained a service contract with one of the world's largest pharmaceutical companies to apply this technology in their drug discovery and development process. The company has also developed various SILAC ready-to-use tissue culture media that facilitate the culture of cell lines for subsequent quantitative proteomics analysis. These special SILAC media have gained customers all over Europe and in North America. 2. Since spinout, the company has commercialised life sciences research reagents including antibodies, recombinant proteins, DNA clones, stable cell lines, etc., many of which have been developed or licensed from Universities/academic institutions. 3. The company has created new jobs by employing five highly skilled staff (3 post-doctoral, two undergraduates). It also provides part-time work to two contractors (bookkeeper and accountant), work to local businesses and outsources some work to the University of Dundee thus providing extra revenue to the institution.
Description Invited Seminar Speaker 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Participants in your research and patient groups
Results and Impact Presentations of results

Regularly invited as a seminar speaker
Year(s) Of Engagement Activity 2006,2007,2008,2009,2010,2011,2012,2013
Description School Visit - Fife 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Presentation of research to school children

Positive feedback from schools and being invited back
Year(s) Of Engagement Activity 2006,2007,2008,2009,2016