The aetiology of traits contributing to autism and the autistic spectrum disorders.

Lead Research Organisation: University of Bristol
Department Name: Community-Based Medicine

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

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Bolton PF (2012) Autism spectrum disorder and autistic traits in the Avon Longitudinal Study of Parents and Children: precursors and early signs. in Journal of the American Academy of Child and Adolescent Psychiatry

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Culpin I (2018) Autistic Traits and Suicidal Thoughts, Plans, and Self-Harm in Late Adolescence: Population-Based Cohort Study. in Journal of the American Academy of Child and Adolescent Psychiatry

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Hebert KJ (2010) Association of autistic spectrum disorder with season of birth and conception in a UK cohort. in Autism research : official journal of the International Society for Autism Research

 
Description Escher Family Fund Grandmaternal smoking and risk of autism
Amount $25,000 (USD)
Funding ID 2015-139645 (3923) 
Organisation Silicon Valley Community Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2015 
End 10/2016
 
Description Exploration of personality and cognitive phenotypes in regard to grandmaternal prenatal smoking.
Amount $25,000 (USD)
Organisation Silicon Valley Community Foundation 
Sector Charity/Non Profit
Country United States
Start 01/2017 
End 12/2017
 
Description Population-based studies to understand depression, anxiety, suicidality and self-harm as adolescent and early adulthood outcomes of autism
Amount £74,096 (GBP)
Organisation Baily Thomas Charitable Fund 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2016 
End 05/2018
 
Description Small grants proposal
Amount £156,235 (GBP)
Funding ID ES/K003356/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 04/2013 
End 09/2014
 
Title ALSPAC autistic traits 
Description 4 different traits independently related to autistic spectrum disorders 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2009 
Provided To Others? Yes  
Impact Publications ongoing - being used by other scientists 
 
Description Characterisation of the placental vascular tree as a biomarker of ASD risk 
Organisation Institute for Basic Research, USA
Country United States 
Sector Academic/University 
PI Contribution Design of the case control sampling, identification of the appropriate ALSPAC placentas, which have been provided blind to the paediatric pathology team for examination.
Collaborator Contribution Of great scientific benefit
Impact This multidisciplinary collaboration includes paediatric pathologists from both the US and UK, epidemiologists and mathematical modellers.
Start Year 2009
 
Description Diagnosing autistic spectrum disorders: health and social implications 
Organisation University of Exeter
Department ESRC Centre for Genomics in Society (EGENIS)
Country United Kingdom 
Sector Public 
PI Contribution I supervise the research with the assistance of Colin Steer in Bristol and others in Exeter
Collaborator Contribution Great scientific benefit
Impact Several publications including, Pubmed: 19735265
Start Year 2008
 
Description Conferences 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Participants in your research and patient groups
Results and Impact Presentation at several conferences international; local presentations in Bristol, at the Institute of Psychiatry; media presentations (radio and TV) and at international conferences in Spain and Norway

Much interest and discussion about possible collaborations
Year(s) Of Engagement Activity 2007,2008,2009,2010
 
Description Presentation at 30 Years of Paediatric Gastroenterology in Bristol & the South West & the Commonwealth 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 10th September 2018. 30 Years of Paediatric Gastroenterology in Bristol and the South West and the Commonwealth. Avon Gorge Hotel du Vin, Bristol. Jean Golding presented: Children of the 90s: stool pattern changes in normal and autistic children and other GI studies.
Year(s) Of Engagement Activity 2018
 
Description Presentation to JGI 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Jean Golding presented: "A life in data" to the Jean Golding Institute Showcase, University of Bristol 3rd July 2018
Year(s) Of Engagement Activity 2018