The role of endothelium in regulating stem cell homing to the liver

Lead Research Organisation: University of Birmingham
Department Name: Clinical and Experimental Medicine

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

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Adams DH (2018) Could endothelial TGFß signaling be a promising new target for liver disease? in Expert review of gastroenterology & hepatology

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Adams DH (2010) Mechanisms of immune-mediated liver injury. in Toxicological sciences : an official journal of the Society of Toxicology

 
Description NIHR BRU in Cell and Immunotherapy for LIver disease
Amount £6,500,000 (GBP)
Organisation National Institute for Health Research 
Department NIHR Birmingham Liver Biomedical Research Unit
Sector Academic/University
Country United Kingdom
Start 09/2008 
End 09/2012
 
Description Edinburgh 
Organisation University of Edinburgh
Department MRC Centre for Inflammation Research
Country United Kingdom 
Sector Academic/University 
PI Contribution We have developed a successful local collaboration with my colleague Dr Newsome andPorfs Forbes and Iredale in Edinburgh resulting an ongoing collaboration which ahs contributed to a recent MRC grant awarded in 2009.
Collaborator Contribution We have several ongoing collaborations sharing technology and expertise
Impact Ongoing publications and research collaborations
Start Year 2008
 
Description Guardian 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact -Article in the Guardian on liver disease and transplantation www.guardian.co.uk/society/2008/nov/28/organ-donation-health-policy-transplant

Incraesed public profile
Year(s) Of Engagement Activity 2008
 
Description PPI initiatve 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Participants in your research and patient groups
Results and Impact 20 members of the public and patients attended a seminar/workshop on liver research in Birmingham

Panel agreed to review our research patient information sheets
Year(s) Of Engagement Activity 2010,2011,2012,2013,2014
 
Description PSC 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Hosted meeting of the PSC patient group to discuss our research
Took on role as Trustee of the Charity in 2013

Asked to host the meeting on an annual basis
Helped develop a research funding programme for the charity
Helped write guieldlines and provide clinical advice
Year(s) Of Engagement Activity 2009,2010,2011,2012,2013,2014
URL http://www.pscsupport.org.uk/?gclid=Cj0KEQiAp4yjBRCE_enjmpug944BEiQATCpLvU1wXwOybMo7BSFeWs_AEICLJAiy...
 
Description Public engagement 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Participants in your research and patient groups
Results and Impact PSC Trust meeting London

Discussion of the potential for stem cell therapy in liver disease. A funding initiative to support genomics in liver disease.
Year(s) Of Engagement Activity 2007
 
Description Schools 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact -Students from local schools come to the department to learn about research and to carry out short projects

Goldcrest award and Nuffield Bursary award
Year(s) Of Engagement Activity 2007,2008,2009,2010,2011,2012,2013,2014,2015
 
Description World hepatitis day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact -Hosted public meeting for World hepatitis day attended by patient groups, politicians, press. Featured on Kerrang Radio & Naked scientist website http://www.thenakedscientists.com/HTML/podcasts/specials/show/2009.06.10/

Increased profile
Year(s) Of Engagement Activity 2009