Establishing the hypothalamo-neuroendocrine axis: role of the infundibulum in hypothalamo-pituitary axon guidance

Lead Research Organisation: University of Sheffield
Department Name: Biomedical Science


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Title Assay for establishment of pituitary stalk, description of novel role for FGFs 
Description Growth factor: role in axonal guidance 
Type Of Material Model of mechanisms or symptoms - in vitro 
Provided To Others? No  
Impact NA 
Title Model of hypothalamic development 
Description In vitro explant culture and associated cell line as tool for hypothalamic cell development 
Type Of Material Model of mechanisms or symptoms - in vitro 
Year Produced 2007 
Provided To Others? Yes  
Impact Working up cell line for knowledge transfer purposes 
Description Role of FGFs in establishing the hypothalamo-neuroendocrine axis 
Organisation University of Cologne
Country Germany 
Sector Academic/University 
PI Contribution Development of core assays, excluding final in vivo work
Collaborator Contribution In vivo zebrafish model system
Impact PhD thesis, publication in preparation
Start Year 2008
Description School visit and workshops 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Extensive contribution to Science Week

Gradual links being forged between local schools and Dept.
Year(s) Of Engagement Activity 2006,2007,2008,2009