Pathfinder Investigation of the Effects of Inflammation on Brain Serotonin Function: Relevance to Depression

Lead Research Organisation: University of Oxford
Department Name: Physiology Anatomy and Genetics


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.


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Description NC3Rs/MRC CRACK IT Review Panel A
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Description BBSRC PhD Studentship
Amount £76,339 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2013
Description BBSRC Strategic Skills Awards
Amount £28,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2010 
End 09/2013
Description Oxford University John Fell Fund
Amount £14,000 (GBP)
Organisation University of Oxford 
Department John Fell Fund
Sector Academic/University
Country United Kingdom
Start 06/2010 
End 05/2011
Description Royal Society Fellowship
Amount £524,445 (GBP)
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2009 
End 08/2013
Description Wellcome Trust Project Grant
Amount £256,289 (GBP)
Funding ID 093223 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2011 
End 12/2013
Description Grant from Pfizer Ltd 
Organisation Pfizer Ltd
Country United Kingdom 
Sector Private 
PI Contribution This was a two year research grant with funding to extend our 5HT fMRI research into a different, but related, area based on our success in the 5-HT system under the Pathfinder Grant.
Impact The postdoc employed under this grant from Pfizer wrote the review of functional imaging in the 5HT system (PMID: 18789342) and which included some details of the work we undertook under this Pathfinder grant.
Start Year 2008
Description MSc and DTC Lectures 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Regular lectures on brain imaging in cancer and neurosciences to Doctoral Training Course and M.Sc. students, which sparked questions and discussion as well as interest in entering research within this field of research. Outcome is often one or more students joining the group for either M.Sc. or D.Phil. projects.

Development of collaborations and numerous examples of interest in applying our VCAM-targeted technology in different patients groups from paediatrics to head injury.
Year(s) Of Engagement Activity 2009,2010,2011,2012,2013,2014,2015,2016