Transgenic control of adrenocorticosteroid synthesis
Lead Research Organisation:
University of Edinburgh
Department Name: Centre for Molecular Medicine
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications



Hadoke PW
(2006)
Altered vascular contractility in adult female rats with hypertension programmed by prenatal glucocorticoid exposure.
in The Journal of endocrinology

Lai M
(2007)
Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia.
in The European journal of neuroscience

Michailidou Z
(2007)
Peripheral mechanisms contributing to the glucocorticoid hypersensitivity in proopiomelanocortin null mice treated with corticosterone.
in The Journal of endocrinology

Michailidou Z
(2008)
Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.
in FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Mullins LJ
(2009)
Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.
in The Journal of biological chemistry

O'Regan D
(2008)
Prenatal dexamethasone 'programmes' hypotension, but stress-induced hypertension in adult offspring.
in The Journal of endocrinology

O'Reilly M
(2006)
Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo.
in Journal of the American Society of Nephrology : JASN
Description | MRC Bridging Support |
Amount | £70,600 (GBP) |
Funding ID | G0701528 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 07/2007 |
End | 06/2008 |
Title | Mouse Model of Congenital Adrenal Hyperplasia |
Description | Genetically modified Cyp11b1 null mouse |
Type Of Material | Model of mechanisms or symptoms - non-mammalian in vivo |
Provided To Others? | No |
Impact | Novel aspects of phenotype relevant to problems of fertility, cardiovascular disease and central nervous system |
Title | kidney microarray database |
Description | Effects of ACTH on kidney gene expression ArrayExpress database www.ebi.ac.uk/array express Accession No: E-MEXP-1761 |
Type Of Material | Biological samples |
Year Produced | 2009 |
Provided To Others? | Yes |
Impact | Publication (19920212) |