Vitamin D and health: genome-wide analysis and insights from Mendelian randomisation.
Lead Research Organisation:
University College London
Department Name: Institute of Child Health
Abstract
Inadequate vitamin D intake has been implicated as a risk factor for many important diseases such as diabetes, cancer and cardiovascular diseases. However, much of the evidence for the health effects of vitamin D comes from observational studies, and conclusions based on these studies may be affected by methodological problems such as bias and confounding. In this study, we will use a novel approach based on genetic information (so-called Mendelian Randomisation) and our aim is to see if the associations between vitamin D and the risk of various diseases can be replicated. If replication is found, this would give further support for a causal association between vitamin D and the outcome of interest. We will use data from the nationwide 1958 British birth cohort, in which over 7000 participants have been followed-up over four decades and detailed information has been collected on genetic markers and a wide-range of health related factors, including vitamin D status, lifestyle, diet, and indicators of disease risk.
Technical Summary
Inadequate vitamin D intake has been implicated as a risk factor for diabetes, cancer and cardiovascular diseases. Much of the evidence for health effects comes from observational studies and may be affected by problems of bias and confounding. The use of vitamin D prophylaxis in intervention studies is limited by concerns of possible toxicity. We propose to carry out a genome-wide analysis on 25(OH)D in the British 1958 cohort study - the first such study in a general population. Further, after identification of genetic variants associated with vitamin D metabolism, we will proceed to apply a mendelian randomization approach to obtaining evidence as to the effects of vitamin D. In mendelian randomization, genetic variants are used as proxy markers for variations in environmentally modifiable exposures (here vitamin D intake and levels). If evidence for an association between vitamin D and disease risk (suggested by other types of studies) can be obtained using mendelian randomization, this would provide evidence for a causal relation. We will evaluate method limitations and the use multiple indicators (located in varying parts of the human genome) as a way of overcoming some of these problems. The key aim of the project is to provide information on an approach, which could provide a safe and cost-effective way of evaluating the influences of vitamin D on health.
Organisations
- University College London, United Kingdom (Collaboration, Lead Research Organisation)
- University of Southampton, United Kingdom (Collaboration)
- University of Turku, Finland (Collaboration)
- University of Edinburgh, United Kingdom (Collaboration)
- University of Gothenburg, Sweden (Collaboration)
- University of Tromsoe, Norway (Collaboration)
- Finnish Institute of Occupational Health (FIOH) (Collaboration)
- Wageningen University, Netherlands (Collaboration)
- Sahlgrenska University Hospital (Collaboration)
- Harvard University (Collaboration)
- University of Liverpool, United Kingdom (Collaboration)
- Massachusetts General Hospital (Collaboration)
- University of Ottawa, Canada (Collaboration)
- University of Helsinki, Finland (Collaboration)
- Agency for Science, Technology and Research (A*STAR) (Collaboration)
- University of Maryland, United States (Collaboration)
- Boston University, United States (Collaboration)
- University of Heidelberg, Germany (Collaboration)
- University of Oxford, United Kingdom (Collaboration)
- Washington University in St. Louis (Collaboration)
- Uppsala University (Collaboration)
- Cedars-Sinai Medical Center (Collaboration)
- University of Bristol, United Kingdom (Collaboration)
- Tufts University (Collaboration)
- Imperial College London, United Kingdom (Collaboration)
- Ludwig Maximilians University Munich (Collaboration)
- London Sch of Hygiene and Trop Medicine, United Kingdom (Collaboration)
- The Wellcome Trust Sanger Institute (Collaboration)
- Erasmus University Rotterdam (EUR) (Collaboration)
- University of Cambridge, United Kingdom (Collaboration)
- Broad Institute (Collaboration)
- University of Miami, United States (Collaboration)
- University of Exeter, United Kingdom (Collaboration)
- Wake Forest University, United States (Collaboration)
- national Institute on Aging (Collaboration)
- Indiana University, United States (Collaboration)
- University of Oulu, Finland (Collaboration)
- McGill University, Canada (Collaboration)
- Tampere University of Technology, Finland (Collaboration)
- University of Aberdeen, United Kingdom (Collaboration)
- Goethe University of Frankfurt am Main, Germany (Collaboration)
- National Institute for Health and Welfare (THL) (Collaboration)
- University of Pittsburgh (Collaboration)
- Addenbrooke's Hospital (Collaboration)
- King's College London, United Kingdom (Collaboration)
Publications
Cavadino Alana
(2012)
Interactions between VDR and RXR polymorphisms affect metabolic traits in the 1958 British birth cohort
in Proceedings of the 4th International Conference in Quantitative Genetics
Chambers JC
(2011)
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
in Nature genetics
Cooper JD
(2011)
Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes.
in Diabetes
Cooper R
(2010)
Associations between parental and offspring adiposity up to midlife: the contribution of adult lifestyle factors in the 1958 British Birth Cohort Study.
in The American journal of clinical nutrition
Cousminer DL
(2013)
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
in Human molecular genetics
Freathy RM
(2010)
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.
in Nature genetics
Horikoshi M
(2013)
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
in Nature genetics
Hyppönen E
(2009)
Serum 25-hydroxyvitamin D and IgE - a significant but nonlinear relationship.
in Allergy
Hyppönen E
(2013)
Vitamin D and pre-eclampsia: original data, systematic review and meta-analysis.
in Annals of nutrition & metabolism
| Guideline Title | Dietary Reference Intakes for Calcium and Vitamin D |
| Description | Citation in IOM recommendations |
| Geographic Reach | North America |
| Policy Influence Type | Citation in clinical guidelines |
| Description | Scottish Vitamin D summit. |
| Geographic Reach | National |
| Policy Influence Type | Participation in a national consultation |
| Impact | Contributed to the evidence base for the need of free vitamin D supplementation. Conclusion by the Scottish governement was, that insufficient evidence to make recommendation at this stage, and avice from SACN will be followed. SACN will be reviewing the evidence again, start 2011. |
| Description | Ergocalciferol (Vitamin D2) vs. Cholecalciferol (Vitamin D3) Food Fortification: Comparative Efficiency in Raising 25OHD Status in Caucasian & Asian Women (PI Lanham-New) |
| Amount | £516,000 (GBP) |
| Funding ID | BB/I006192/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2011 |
| End | 03/2014 |
| Description | Programme in applied and translational cardiovascular genomics:UCLEB (PI Hingorani) |
| Amount | £9,500,000 (GBP) |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2011 |
| End | 03/2016 |
| Description | Public Health Importance of Vitamin D (PI Lawlor) |
| Amount | £1,400,000 (GBP) |
| Funding ID | G0701603 |
| Organisation | Medical Research Council (MRC) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2009 |
| End | 09/2013 |
| Description | UCL Impact PhD studentship (PI Hypponen) |
| Amount | £63,253 (GBP) |
| Organisation | University College London |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 06/2011 |
| End | 06/2014 |
| Description | Vitamin D -CVD/related traits (PI Hypponen) |
| Amount | £217,000 (GBP) |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2010 |
| End | 09/2013 |
| Description | vitamin D and metabolic health; 1966 cohort programme (Hypponen CO-PI with Jarvelin) |
| Amount | £341,714 (GBP) |
| Organisation | Academy of Finland |
| Sector | Public |
| Country | Finland |
| Start | 01/2011 |
| End | 12/2013 |
| Title | MR analyses on Vitamin D |
| Description | Methodological paper describing issues related to using genetic variants as instruments in Mendelian Randomisation studies on vitamin D |
| Type Of Material | Data analysis technique |
| Year Produced | 2012 |
| Provided To Others? | Yes |
| Impact | Methods paper,published in open access journal, highlighted by the Faculty1000 as a paper of special interest. |
| Title | NFBC1966 25(OH)D consentrations |
| Description | We have measured 25(OH)D consentrations from the participants in the Northern Finland Birth cohort (NFBC)1966 . |
| Type Of Material | Database/Collection of Data/Biological Samples |
| Year Produced | 2008 |
| Provided To Others? | Yes |
| Impact | This extends the data available from NFBC1966, a large resource for population based studies. So far we have used this information as outcome in genomewide association analyses. (Ongoing, also part of SUNLIGHT collaboration). |
| Title | Seasonality methods |
| Description | Methodological paper describing methods to enable inferences (and quantification) of association for the role of vitamin d to be derived from related seasonal variations. |
| Type Of Material | Data analysis technique |
| Provided To Others? | No |
| Impact | Awaiting formal publication. Methods description will allow the application of methodology to other contexts. |
| Description | D-CarDia |
| Organisation | Boston University |
| Department | School of Public Health |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | Harvard University |
| Department | Harvard Medical School |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | Harvard University |
| Department | Harvard T.H. Chan School of Public Health |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | Heidelberg University |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | King's College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | Ludwig Maximilian University of Munich (LMU Munich) |
| Department | Center for Integrated Protein Science Munich (CIPSM) |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | McGill University |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | Sahlgrenska University Hospital |
| Country | Sweden |
| Sector | Hospitals |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | Tampere University of Technology |
| Country | Finland |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Exeter |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Helsinki |
| Country | Finland |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Maryland |
| Department | School of Medicine Maryland |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Oulu |
| Department | Biocenter Oulu |
| Country | Finland |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Tromso |
| Country | Norway |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Turku |
| Country | Finland |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | University of Wageningen |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | Uppsala University |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | D-CarDia |
| Organisation | Wake Forest University |
| Department | Wake Forest School of Medicine |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | EH leads collaboration, ICH main is the analysis site with a post doc appointed for the management of the project with BHF funding (PG/09/023/26860). Research fellow appointed with MRC funding (G0601653), acted as the main analyst for the collaboration (2010-2012). |
| Collaborator Contribution | Collaborators have provided results for the meta-analyses carried out at UCL ICH. |
| Impact | One large meta-analysis submitted, other in advanced draft stages, two further meta-analyses about to be submitted. |
| Start Year | 2010 |
| Description | EGG/EAGLE |
| Organisation | University of Oxford |
| Department | Oxford Centre for Diabetes Endocrinology and Metabolism (OCDEM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Statistician working on this MRC funded project, has carried out GWAs meta-analyses and within cohort GWA analyses on birth weight among other tasks, contributing to the work in EGG consortium. Member of EAGLE Steering group, collaborative meta-anlyses on various traits under way. |
| Collaborator Contribution | This collaboration has opened possibilities to collaborate with several large consortia, including EGG, EAGLE, Diagram. Some related outputs have been submitted for publication, others to follow. |
| Impact | These collaborations have already led, and will continue to lead, to further added value for the current MRC funded project, beyond work directly related to vitamin D. |
| Description | MRC Centre |
| Organisation | University College London |
| Department | MRC Centre for Epidemiology for Child Health |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | My research team are an active member in the centre, with a strive to influence policy and practice and contributions to the genetic epidemiolgy group. |
| Collaborator Contribution | • Provision of Epilab: The epiLab is an advanced computing environment and data management service that has been developed at the MRC Centre to support researchers through all aspects of the research data management life-cycle. The service provides core data storage and backup provision in conjunction with a virtualised desktop and backend-server infrastructure, designed to provide high levels of resilience and information security. |
| Impact | Facilitated by the resources provided by the centre, I have expanded my group, published several papers in high profile publications, obtained further research funding, including the new Birth Cohort Resource (in which I am a co-investigator). |
| Start Year | 2007 |
| Description | NFBC 1966 |
| Organisation | Imperial College London |
| Department | Department of Epidemiology and Biostatistics |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We have extended the NFBC resource by information on 25(OH)D consentrations. We have also improved the data available by extensive re-coding of data, to allow the retrieval of supplementation data from medications used. |
| Collaborator Contribution | Allows us to use the NFBC resource. The joint recent funding, will contribute towards salary costs for a statistician who will help to take forward collaborative VitD related analyses. |
| Impact | 25OHD consentrations, supplementation data. |
| Description | SUNLIGHT |
| Organisation | Addenbrooke's Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Agency for Science, Technology and Research (A*STAR) |
| Department | Genome Institute of Singapore |
| Country | Singapore |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Boston University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Broad Institute |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Cedars-Sinai Medical Center |
| Country | United States |
| Sector | Hospitals |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Erasmus University Rotterdam |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Finnish Institute of Occupational Health (FIOH) |
| Country | Finland |
| Sector | Public |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Goethe University Frankfurt |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Harvard University |
| Department | Harvard Medical School |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Indiana University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | King's College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Massachusetts General Hospital |
| Country | United States |
| Sector | Hospitals |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | McGill University |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | National Institute for Health and Welfare (THL) |
| Country | Finland |
| Sector | Public |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | National Institute on Aging |
| Country | United States |
| Sector | Public |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | The Wellcome Trust Sanger Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Tufts University |
| Department | Institute for Ageing Research |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University College London |
| Department | Institute of Child Health |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Aberdeen |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Gothenburg |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Helsinki |
| Country | Finland |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Maryland |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Miami |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Ottawa |
| Department | Faculty of Medicine |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Oulu |
| Department | Biocenter Oulu |
| Country | Finland |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Oxford |
| Department | Kennedy Institute of Rheumatology |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Pittsburgh |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | University of Washington |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | SUNLIGHT |
| Organisation | Wake Forest University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Co-leading, contributed with MRC funded project ~30% samples for Lancet publication , ICH lead analysis site for second round of meta-analysis. ICH allocated to lead on subsequent sub-analyses. |
| Collaborator Contribution | Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output.Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. Scientific collaboration leading to high quality output. |
| Impact | 1. *Wang T, *Zhang F, *Richards B, *Kestenbaum B, *van Meurs J, *Berry D, (67 others),*Todd J, *Dupuis J, *Hyppönen E, *Spector T. Common genetic determinants of vitamin D insufficiency: The SUNLIGHT consortium. Lancet. 2010. *contributed equally, EH corresponding author. Two related presentations given at HUGO and CELSE meetings in 2010. Two further SUNLIGHT papers currently under preparation, several in planning. |
| Start Year | 2008 |
| Description | UCLEB programme |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-ordinated the 1958BC contribution to the analyses. MRC grant funded analyst carrying out the analysis on 1958BC |
| Collaborator Contribution | Scientific collaboration leading to high quality output. The funding provided by the collaboration will contribute towards salary costs for a statistician. |
| Impact | 2 papers published. Recently we obtained specific funding to continue this work (Collaborative programme grant fom BHF). |
| Start Year | 2007 |
| Description | UCLEB programme |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-ordinated the 1958BC contribution to the analyses. MRC grant funded analyst carrying out the analysis on 1958BC |
| Collaborator Contribution | Scientific collaboration leading to high quality output. The funding provided by the collaboration will contribute towards salary costs for a statistician. |
| Impact | 2 papers published. Recently we obtained specific funding to continue this work (Collaborative programme grant fom BHF). |
| Start Year | 2007 |
| Description | UCLEB programme |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-ordinated the 1958BC contribution to the analyses. MRC grant funded analyst carrying out the analysis on 1958BC |
| Collaborator Contribution | Scientific collaboration leading to high quality output. The funding provided by the collaboration will contribute towards salary costs for a statistician. |
| Impact | 2 papers published. Recently we obtained specific funding to continue this work (Collaborative programme grant fom BHF). |
| Start Year | 2007 |
| Description | UCLEB programme |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-ordinated the 1958BC contribution to the analyses. MRC grant funded analyst carrying out the analysis on 1958BC |
| Collaborator Contribution | Scientific collaboration leading to high quality output. The funding provided by the collaboration will contribute towards salary costs for a statistician. |
| Impact | 2 papers published. Recently we obtained specific funding to continue this work (Collaborative programme grant fom BHF). |
| Start Year | 2007 |
| Title | Gene discovery, 25(OH)D |
| Description | Novel genetic variants affecting 25(OH)D consentrations and birth weight. |
| IP Reference | |
| Protection | Protection not required |
| Year Protection Granted | 2011 |
| Licensed | No |
| Impact | These discoveries have led to opportunities to use information on the genes/SNPs implicated, as instruments in "Mendelian randomisation" analyses and/or offered insights into biological pathways related to these traits. |
| Title | Gene discovery, childhood obestiy |
| Description | Novel genetic variants affecting propensity to obesity in childhood. |
| IP Reference | |
| Protection | Protection not required |
| Year Protection Granted | 2011 |
| Licensed | No |
| Impact | Increased knowledge about the importance of genetic variation in affecting childhood obesity. |
| Title | Genetic influences on vitamin D deficiency |
| Description | We described to ability to predict the risk of vitamin D deficiency using common genetic variations. This work was funded by the MRC, but also by other sources as relevant to the SUNLIGHT collaboration. |
| Type | Diagnostic Tool - Non-Imaging |
| Current Stage Of Development | Refinement. Non-clinical |
| Year Development Stage Completed | 2010 |
| Development Status | Under active development/distribution |
| Impact | It demonstrated the relatively small but relevant contribution of genetic variation as a determinant of the risk of vitamin D deficiency. Raises some question about the suitability of currently used biomarker for the measurement of vitamin D status, highlighting the need of further research. |
| Description | Annual meeting of British Society of Allergy and Clinical Immunology |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Primary Audience | Health professionals |
| Results and Impact | Part of scietific vitamin D symposium. Knowledge dissemination |
| Year(s) Of Engagement Activity | 2011 |
| Description | BBC4 Case Notes radio programme |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Hypponen gave interview which was included in a programme on "Sun and Skin" Contacts from audience. |
| Year(s) Of Engagement Activity | 2008 |
| Description | BBC4 Radio Case notes |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Hypponen appeared on a radio programme on Vitamin D Distribution of information through radio. |
| Year(s) Of Engagement Activity | 2010 |
| Description | BBC4 Radio food programme |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Primary Audience | Public/other audiences |
| Results and Impact | Dr Hypponen gave a interview for a programme focused on Vitamin D Contacts from audience. |
| Year(s) Of Engagement Activity | 2010 |
| Description | British Science Festival |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Primary Audience | Public/other audiences |
| Results and Impact | Presentation was given about hypovitaminosis D in Britain and related health consequences in a related seminar targeted at a lay audience. Interviews to three journalists who we at the audience, led to related articles in a scottish newspaper, main Finnish lay science magazine ("Tiede lehti") and a fairly lengthy article in the "Chemistry World", a magazine published by the Royal Society of Chemistry. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Interviewed as corresponding co-author in the SUNLIGHT consortium for Lancet press release |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Primary Audience | Public/other audiences |
| Results and Impact | Global distribution of news. The interview was distributed through Reuters |
| Year(s) Of Engagement Activity | 2010 |
| Description | Invited talk at Conference of the Nordic Midwives Association |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Primary Audience | Health professionals |
| Results and Impact | Dr Hypponen gave an invited talk on Vitamin D in pregnancy and the implications for the mother and child Issues related to presentation were covered by Nordic press/professional journals. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Measuring and improving vitamin D promotion and prescribing to prenatal and postnatal women within the Northwest. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | Yes |
| Primary Audience | Health professionals |
| Results and Impact | A meeting to advice on the implementation of vitamin D recommendations within the PCT Implementation of vitamin D recommendations during pregancy within the PCT. |
| Year(s) Of Engagement Activity | 2011 |
| Description | Media contact, various |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Primary Audience | Public/other audiences |
| Results and Impact | Various pieces for newspapers (Daily Mail, Telegraph etc.) and magazines (Mens Health, others), mainly responding to queries related to Vitamin D. Knowledge dissemination |
| Year(s) Of Engagement Activity | 2011 |
| Description | Press briefing, Science Media Centre |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Dr Hypponen was one of the experts on a background briefing session on vitamin D. A related article appeared in The Independent. Dr Hypponen was subsequently interviewed by a Brazilian Health journalist and a journalist affiliated with the American Diabetes Association. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Press release on review paper on Vitamin D in pregnancy |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Primary Audience | Public/other audiences |
| Results and Impact | The press release was picked up by BBC Radio 4 news and attracted strong interest with distribution through several news agencies. Contacts from GPs, members of public, members of pharmaceutical companies. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Public Engagment event, Wellcome trust |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Primary Audience | Health professionals |
| Results and Impact | Seminar with an active multidiciplinary audience. Presentation was recored and posted in the you tube. Further invitations to speak from members in the audience. |
| Year(s) Of Engagement Activity | 2011 |
| Description | Scottish Summit on Vitamin D |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Dr Hypponen gave an invited talk on Vitamin D and insights from epidemiological studies at a meeting jointly organised by the Scottish MS Society and the Scottish Government. Action to improve vitamin D status in Scotland. |
| Year(s) Of Engagement Activity | 2010 |
| Description | Symposium on "Critical micronutrients in pregnancy, lactation and infancy" . Munich Germany. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | Yes |
| Primary Audience | Health professionals |
| Results and Impact | Seminar to discuss research needs for evaluating the effect of micronutrient defencies on pregnancy outcomes. Publication in Annals of Nutrition and Metabolism, in press. |
| Year(s) Of Engagement Activity | 2011 |
| Description | The 2nd Peckham symposium, ICH UCL |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Primary Audience | Health professionals |
| Results and Impact | A well attended annual "flagship" symposium for our Department. Knowledge dissemination |
| Year(s) Of Engagement Activity | 2011 |