Prevention IMPACT: developing and evaluating economic models for planning optimal cardiovascular prevention strategies

Lead Research Organisation: University of Liverpool
Department Name: Population Community and Behavioural Sci

Abstract

Preventing future heart disease and stroke is difficult. Challenges include: complex causes, diverse diseases, climbing costs and conflicting risk factor trends (less smoking, more obesity, more diabetes, and persistent poverty).

We will therefore:
# identify different ways to reduce risk factors in high-risk individuals and in whole populations (by searching the evidence literature and consulting NHS decision-makers);
# extend a widely used computer prediction model for heart disease to include stroke and peripheral artery disease;
# develop Web-based forms of the model for NHS users;
# compare the effectiveness and cost-effectiveness of different prevention plans;
# discuss our results with planners, policy makers, professionals and patient groups.

Technical Summary

The prevention of future cardiovascular disease (CVD) remains problematic. Planning and prediction challenges include: complex causes, diverse manifestations, increasing costs, population ageing and conflicting trends in obesity, diet, smoking and inequalities.

Our multi-disciplinary group will therefore:
# systematically review the scientific evidence;
# elicit the views of NHS decision-makers;
# identify a range of policy options;
# further develop a validated coronary policy model to include stroke and other CVD;
# compare the effectiveness and cost-effectiveness of different risk factor reduction strategies in high risk individuals and in entire populations;
# share results with planners, policy-makers, professionals and patient groups.

Publications

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Aveyard P (2016) Should we welcome food industry funding of public health research? in BMJ (Clinical research ed.)

 
Description AOMRC Obesity Steering Group
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Description BHF Prevention & Care Committee
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Impact Potentially Influential
 
Description Chair of UK Faculty of Public Health Cardiovascular Health Committee
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Impact Occasionally positive
 
Description Trustee & Board Member, National Heart Forum
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Impact Occasionally substantial
 
Description Vice President for Policy, UK Faculty of Public Health
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
Impact Advice to DH Public Health System Group Advice to Parliamentary Health Select Committee
 
Description WHO Diet Action Plan
Geographic Reach Europe 
Policy Influence Type Participation in a advisory committee
 
Description British Heart Foundation Programme Grant
Amount £215,000 (GBP)
Funding ID Eric Brunner (PI) 
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2013 
End 03/2017
 
Description Department of Health HTA 2007-2009 The RATPAC Trial: Randomised Assessment of Treatment using Panel Assay of Cardiac markers ISRCTN 37823923
Amount £776,213 (GBP)
Organisation National Institute for Health Research 
Department Health Technology Assessment Programme (HTA)
Sector Public
Country United Kingdom
Start 04/2007 
End 03/2009
 
Description E-Health Informatics Research Centres (E-HIRCs) Call
Amount £4,700,000 (GBP)
Funding ID MR/K006665/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2013 
End 03/2018
 
Description European Commission EAHC
Amount £1,000,100 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 04/2011 
End 03/2013
 
Description European Commission FP7
Amount £66,000 (GBP)
Funding ID 281640 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 06/2011 
End 05/2015
 
Description NIH RO1
Amount $450,000 (USD)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 08/2016 
End 07/2020
 
Description NIHR Health Technology Assessment Programme
Amount £800,000 (GBP)
Funding ID 16/165/01 
Organisation NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) 
Sector Academic/University
Country United Kingdom
Start 11/2017 
End 10/2019
 
Description NIHR School for Public Health Research
Amount £2,500,000 (GBP)
Funding ID M Whitehead (PI) 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2012 
End 03/2017
 
Description EuroHeart 2 
Organisation European Heart Network EHN
Country Belgium 
Sector Charity/Non Profit 
PI Contribution Major role in developing and finalising EU bid [now successful].
Collaborator Contribution Strengthened and extended a European network collaborating on policy improvements in food and tobacco [heart health]Effective policy collaborations
Impact Funding of 1.3 million Euros. Project will run over three years 2011-2014
Start Year 2010
 
Description EuroHeart 2 
Organisation European Society of Cardiology (ESC)
Country European Union (EU) 
Sector Charity/Non Profit 
PI Contribution Major role in developing and finalising EU bid [now successful].
Collaborator Contribution Strengthened and extended a European network collaborating on policy improvements in food and tobacco [heart health]Effective policy collaborations
Impact Funding of 1.3 million Euros. Project will run over three years 2011-2014
Start Year 2010
 
Description Tufts Friedman School of Nutrition 
Organisation Tufts University
Department Friedman School of Nutrition Science and Policy
Country United States 
Sector Academic/University 
PI Contribution Modelling food policy and cardiovascular trends
Collaborator Contribution Epidemiology and systematic reviews
Impact Thus far, abstracts at AHA and SSM conferences. Several manuscripts in preparation
Start Year 2011
 
Description BBC Radio4 Today programme 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Paper Presentation
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Several subsequent invitations to talk on media outlets

Several subsequent invitations to talk about CVD prevention and food policy
Year(s) Of Engagement Activity 2013
URL http://www.bbc.co.uk/news/health-22964978