Understanding the role of the fibrosis assosiated chaperone Hsp47 in collagen synthesis

Lead Research Organisation: University of Birmingham
Department Name: Sch of Biosciences

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

10 25 50
 
Description Chair of Policy Committee - Biochemical Soceity
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
Impact The policy committee at BS makes recommendations on a range of issues related to Biochemistry
 
Description Member of the Uk Synthetic Biology Leadership Council
Geographic Reach National 
Policy Influence Type Participation in advisory committee
Impact The SBLC is a ministerial committee charged with the development of a Synthetic Biology within the UK
 
Description Advantage West Midlands, Technology Transfer Fund
Amount £25,000 (GBP)
Organisation Advantage West Midlands 
Sector Public
Country United Kingdom
Start 01/2005 
End 01/2006
 
Description BBSRC Equipment Grant
Amount £191,475 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 01/2004 
End 01/2006
 
Description EPSRC Project Grant GR/T09224/01 Development of linear dichroism into a structural tool for characterisation of polymeric fibres particularly peptides and proteins
Amount £345,468 (GBP)
Funding ID GR/T09224/01 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 01/2005 
End 01/2008
 
Description EPSRC follow on funding EP/G005869/1 Rapid and simple clinical assays using nanoscale phage-based detectors and linear dichroism spectroscopy
Amount £102,376 (GBP)
Funding ID EP/G005869/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 01/2008 
End 01/2009
 
Description Equipment
Amount £25,000 (GBP)
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2004 
End 01/2006
 
Title Linear Dichroism Instrument 
Description The worlds first linear dichroism instrument customised for use with biological samples 
Type Of Material Technology assay or reagent 
Year Produced 2006 
Provided To Others? Yes  
Impact Has led to new insights into the behaviour of DNA, membrane proteins and protein fibres 
 
Description Construction of a low volume linear dichroism cell 
Organisation Crystal Precision Optics
Country United Kingdom 
Sector Private 
PI Contribution We developed an instrument that was built in collaboration with a UK SMA CPo
Collaborator Contribution CPO have provided engineering expertise important in the construction of a viable commercial LD cell
Impact CPO have provided engineering expertise important in the construction of a viable commercial LD cell
 
Description Construction of a low volume linear dichroism cell 
Organisation JASCO UK Ltd
Country United Kingdom 
Sector Private 
PI Contribution We developed an instrument
Collaborator Contribution JASCO have provided Market support to allow the new LD cell to become a worldwide product
Impact JASCO have provided Market support to allow the new LD cell to become a worldwide product
 
Title A COMPOSITION 
Description The invention provides light-emitting compositions, including lasing and fluorescent compositions. The invention particularly relates to programmable biological substrates, which fluoresce and/or lase, and which have a wide variety of different applications. The invention extends to use of the fluorescent compositions and lasing compositions comprising programmable biological substrates in fabricating lasers, and in various biological imaging applications, such as in assays. 
IP Reference WO2013093499 
Protection Patent application published
Year Protection Granted 2013
Licensed No
Impact Viral laser
 
Title Linear Dichroism Cell 
Description Low Volume Couette Cell customised for Biological Samples 
IP Reference US2010053619 
Protection Patent granted
Year Protection Granted 2010
Licensed Commercial In Confidence
Impact formed core IP for formation of an SME, Dioptica Scientific Limited
 
Title Linear Dichroism Cell 
Description Linear Dichroism Couette for Biological Samples 
Type Support Tool - For Fundamental Research
Current Stage Of Development Small-scale adoption
Year Development Stage Completed 2006
Development Status Under active development/distribution
Impact See other sections 
 
Company Name Linear Diagnostics Ltd 
Description Diagnostics company specialising in Agri/medical and defense applications 
Year Established 2012 
Impact NA
 
Company Name Dioptica Scientific Ltd 
Description Manufactures Specialised Linear Dichroism Cells; NULL 
Year Established 2006 
Impact See previous sections