MRC Social, Genetic and Developmental Psychiatry Centre

Lead Research Organisation: King's College London
Department Name: Social Genetic and Dev Psychiatry Centre

Abstract

Nearly all psychiatric disorders are influenced by both genes and environment, often in equal measure, and most adult psychiatric disorders originate in childhood. For these reasons, the MRC Social, Genetic and Developmental Psychiatry (SGDP) Centre was launched in 1994 as the first of the MRC?s large interdisciplinary research centres in order to bring together social (environmental) and genetic strategies to understand the development of mental health and illness. The MRC SGDP Centre continues to be the only centre of excellence nationally or internationally with this interdisciplinary theme. The focus of the MRC SGDP Centre is on common psychiatric disorders that have a huge impact on people?s everyday lives such as mood disorders (anxiety and depression), ?externalising? disorders (disruptive behaviour including hyperactivity and addictions), and cognitive disorders (learning disabilities and the autistic spectrum). The Centre?s mission includes research, translation and training.

To achieve its research mission, the Centre has successfully recruited a broad range of 28 experts from psychiatry, psychology, neuroscience, molecular genetics, and quantitative and statistical genetics and facilitated their working together in the Centre?s new #16-million building. The hallmark of the MRC SGDP Centre is collaborative interdisciplinary research, which has produced pioneering findings at the developmental interface between genes and environment with far-reaching implications for diagnosis, treatment and prevention of mental illness. In order to add to the synergy created by its SGDP themes and existing resources, the Centre?s major new research request for 2010-15 is to develop three new resource areas ? bioinformatics, epigenetics and electrophysiology.

The second aspect of the Centre?s mission is to translate its research findings to clinical practice and public health policy. Translation of the Centre?s research is facilitated by its status as a department of the Institute of Psychiatry, which is a world-class psychiatric research institution and is in partnership with the Maudsley Hospital and the South London and Maudsley NHS Foundation Trust, the premier NHS mental health trust.

In terms of its training mission, the Centre?s 4-year PhD programme - launched in 1997, the first of its kind in the UK - continues to thrive, with nine new students accepted each year all of whom are supported with studentships. The Centre makes its expertise available more widely through its annual one-week Summer School for 70-100 researchers and doctors from around the world. A goal of the Centre during 2010-2015 is to greatly extend its educational reach through the development of e-learning programmes.

Technical Summary

Founded in 1994, the MRC Social, Genetic and Developmental Psychiatry (SGDP) Centre?s overarching theme is to bring together social (environmental) and genetic strategies to study the development of mental health and illness. Its focus is on common psychiatric disorders that emerge in childhood such as mood disorders (anxiety and depression), ?externalising? disorders (disruptive behaviour including hyperactivity and addictions), and cognitive disorders (learning disabilities and the autistic spectrum). The MRC SGDP Centre now includes 28 researchers with permanent appointments whose offices, students and research teams are in the MRC SGDP building. During 2005-09, the Institute of Psychiatry (IoP) has invested heavily in the Centre, with continuing commitments that will cost #10m during 2010-15. In addition, the IoP has committed an additional #2m in new money during 2010-15 if the Centre is renewed.

The Centre?s mission includes research, translation and training. Its progress in research at the developmental intersection between genes and environment has been outstanding as assessed in terms of collaboration, impact of publications and grants. A key feature of the Centre?s progress during the current grant period has been the appointment of seven new researchers who will increase the Centre?s strength at multiple levels of analysis between genes and behaviour. In order to add to the synergy created by its SGDP themes and existing resources in molecular and statistical genetics, the Centre?s major new research request for 2010-15 is to develop three new resource areas ? bioinformatics, epigenetics and electrophysiology ? with diminishing support over the five years as these resource areas become self-supporting by contributing to new research grants.

Translating research findings into knowledge useful for improving health is a strength of the Centre because the Centre is embedded within IoP with its unrivalled strengths in psychiatric research and with its strong links with South London and Maudsley NHS Foundation Trust which is the premier mental health trust in the UK. In terms of training, the Centre?s 1+3 MSc/PhD programme has doubled in size during the current grant period to nine students per year all of whom are fully supported with studentships. For 2010-15, support is requested for four studentships which is half of the Centre?s total budget request. The Centre makes its expertise available more widely through its self-supporting annual one-week Summer School for 70-100 researchers. The present proposal requests support to extend our educational research throughout the world by the development of e-learning programmes.

Organisations

Publications

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Booth RDL (2018) Evidence of Reduced Global Processing in Autism Spectrum Disorder. in Journal of autism and developmental disorders

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Brewer R (2016) Can Neurotypical Individuals Read Autistic Facial Expressions? Atypical Production of Emotional Facial Expressions in Autism Spectrum Disorders. in Autism research : official journal of the International Society for Autism Research

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Brunsdon VE (2014) Exploring the 'fractionation' of autism at the cognitive level. in Autism : the international journal of research and practice

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Carter Leno V (2015) Callous-unemotional traits in adolescents with autism spectrum disorder. in The British journal of psychiatry : the journal of mental science

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Elmose M (2014) Being aware of own performance: how accurately do children with autism spectrum disorder judge own memory performance? in Autism research : official journal of the International Society for Autism Research

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Euesden J (2015) The relationship between schizophrenia and rheumatoid arthritis revisited: genetic and epidemiological analyses. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

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Euesden J (2015) PRSice: Polygenic Risk Score software. in Bioinformatics (Oxford, England)

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Franke B (2018) Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan. in European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

 
Description Alina Rodriguez - ESF Review Panel Member - 2010 to 2011
Geographic Reach Asia 
Policy Influence Type Membership of a guidance committee
Impact Dr Alina Rodriguez was a member of the European Science Foundation review panel for 2010-2011. The European Science Foundation provides a common platform for its Member Organisations in order to: - advance European research - explore new directions for research at the European level Through its activities, the ESF serves the needs of the European research community in a global context. As an independent, non-governmental organisation dedicated to pan-European scientific networking and collaboration, the ESF has had a key role to play in mediating between a multitude of heterogeneous research cultures and agencies. The ESF hosts an array of instruments to accommodate various types and levels of international collaboration, within Europe and beyond. http://www.esf.org
URL http://www.esf.org
 
Description Alina Rodriguez - Scientific Committee - International Assoc for Child and Adolescent Psychiatry
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact Dr Alina Rodriguez, based at the MRC SGDP Centre, is on the Scientific committee of the 22nd International Association for Child and Adolescent Psychiatry and Allied Professions World Congress. She will serve on this committee from 2011 to 2016
 
Description Arseneault - Dept for Transport's report on road safety policy and childhood accidents
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research that showed how low self-control during childhood could explain the association between early delinquency and adolescent accidents was cited in the Department for Transport's policy article and road safety report: "Childhood accidents and their relationship with problem behavior". http://www.dft.gov.uk/pgr/roadsafety/research/rsrr/theme1/childhoodaccidentsandtheirre4729?page=6
URL http://www.dft.gov.uk/pgr/roadsafety/research/rsrr/theme1/childhoodaccidentsandtheirre4729
 
Description Arseneault - UK Home Office ACMD - cannabis use in adolescents and risk for adult psychosis
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact The research on examining the association between cannabis and psychosis, and the research on cannabis use in adolescents and risk for adult psychosis, were both cited in the UK Home Office Advisory Council on the Misuse of Drugs (ACMD) article "Further consideration of the classification of cannabis under the Misuse of Drugs Act 1971" http://drugs.homeoffice.gov.uk/publication-search/acmd/cannabis-reclass-2005?view=Binary
URL http://drugs.homeoffice.gov.uk/publication-search/acmd/cannabis-reclass-2005?view=Binary
 
Description Arseneault - UK Office of Science and Technology - Foresight review
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research that examined the causal evidence between cannabis use and adult psychosis was cited in the UK Office of Science and Technology's Foresight Programme article "Neuroscience and drugs of addiction". http://www.foresight.gov.uk/Brain%20Science/Neuroscience.pdf
URL http://www.foresight.gov.uk/Brain%20Science/Neuroscience.pdf
 
Description Bolton - Test accuracy and retest reliabailty of the CAST - DHSSPNI
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in clinical reviews
Impact Research on test accuracy of the CAST and the re-test reliability of the CAST were cited by the DHSSPNI (N. Ireland Dept. of Health, Social Services and Public Safety) for their "Independent Review of Autism Services - Final Report". (6th May 2008) www.dhsspsni.gov.uk/independent_review_of_autism_services_final_report.pdf
URL http://www.dhsspsni.gov.uk/independent_review_of_autism_services_final_report.pdf
 
Description Bolton - evidence for screening for Autism disorders - DHSSPNI
Geographic Reach National 
Policy Influence Type Citation in clinical reviews
Impact Research that examined the evidence for screening for Autism disorders was cited by the DHSSPNI (N. Ireland Dept. of Health, Social Services and Public Safety) for their "Independent Review of Autism Services - Final Report". (6th May 2008) www.dhsspsni.gov.uk/independent_review_of_autism_services_final_report.pdf
URL http://www.dhsspsni.gov.uk/independent_review_of_autism_services_final_report.pdf
 
Description Breen - ISPGPC for the World Congress of Psychiatry Genetics in 2014
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
 
Description Canadian Govt Report - Early Childhood Development (Moffit Dunedin Erisk Studies)
Geographic Reach North America 
Policy Influence Type Gave evidence to a government review
Impact The Canadian Academy of Health Sciences Expert Panel and The Royal Society of Canada presented a Government report on Early Childhood Development on 15 November 2012. Much of the evidence on childhood development, and the recommendations for policy, were based directly on research by Prof Moffitt, Prof Caspi, Dr Arseneault, Dr Jaffee and Prof I Craig, based on longitudinal studies run in Dunedin and with the Environmental Risk teams at the SGDP Centre.
 
Description Caspi and Modditt - sex differences in reading disability - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on sex-differences in developmental reading disability was cited in the Government office for Science Foresight Project's State of Science Review on Dyslexia in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D2_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D2_MCW.pdf
 
Description Caspi and Moffit - Low children's SES and adult health - DCSF Research Report
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Longitudinal research on the association between children's experience of socio-economic disadvantage and adult health was cited in the Research report DCSF-RW022 for the Dept. for Children, School and Families, "The "Family - Nurse Partnership": developing an instrument for identification, assessment and recruitment of clients" (October 2007). http://www.dcsf.gov.uk/research/data/uploadfiles/DCSF-RW022.pdf
URL http://www.dcsf.gov.uk/research/data/uploadfiles/DCSF-RW022.pdf
 
Description Caspi and Moffit - Sex differences in antisocial conduct behavior - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on Sex differences in antisocial conduct behavior was cited in the Government office for Science Foresight Project's State of Science Review on The Neuroscience of Social Cognition in Teenagers in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) www.foresight.gov.uk/Mental%20Capital/SR-E15_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-E15_MCW.pdf
 
Description Caspi and Moffit - life stress, depression and adult psychiatric disorders - Office for Science Foresight Project's State of Science Review
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in systematic reviews
Impact Research on the influence of life-stress on depression and the research on behavioral observations of 3 yr-olds predicting adult psychiatric disorders were both cited in the Government office for Science Foresight Project's State of Science Review on Psychological Wellbeing: The evidence regarding it's causes and consequences, in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-X2_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-X2_MCW.pdf
 
Description Caspi and Moffitt - Breast feeding and IQ - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact 17. The XXX-funded research on genetic variations in fatty acid metabolisms and the effect of breast-feeding on IQ was cited in the Government office for Science Foresight Project's State of Science Review on Nutrition and Cognitive Health in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) www.foresight.gov.uk/Mental%20Capital/SR-E18_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-E18_MCW.pdf
 
Description Caspi and Moffitt - Cannabis use and psychosis - Misuse of Drugs report to Home Office
Geographic Reach National 
Policy Influence Type Citation in clinical reviews
Impact Research on the trends of cannabis use in S.E London and schizophrenia, and research on the effect of adolescent-onset cannabis use on adult psychosis were both cited in the UK Advisory Council on the Misuse of Drugs report to the UK Home Office "Cannabis: Classification and Public Health" (April 2008) http://drugs.homeoffice.gov.uk/publication-search/acmd/acmd-cannabis-report-2008?view=Binary
 
Description Caspi and Moffitt - Children's experience of low SES - Home Office Research Development and Statistics Directorate
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Longitudinal research on the association between children's experience of socio-economic disadvantage and adult health was cited in the UK Home Office Research Development and Statistics Directorate Online Report "Predictive factors for illicit drug use among young people: a literature review" (May 2007) http://www.homeoffice.gov.uk/rds/pdfs07/rdsolr0507.pdf
URL http://www.dcsf.gov.uk/research/data/uploadfiles/DCSF-RW022.pdf
 
Description Caspi and Moffitt - MAOA, maltreatment and gene-environment interaction predicint children's mental health - Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on MAOA, maltreatment and gene-environment interaction predicting children's mental health was cited in the Government office for Science Foresight Project's State of Science Review on Conduct Disorder and Antisocial behavior in the Under-Fives in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D8_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D8_MCW.pdf
 
Description Caspi and Moffitt - Mental disorders and violence in a birth cohort -Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on Mental disorders and violence in a total birth cohort was cited in the Government office for Science Foresight Project's State of Science Review on Linkages Between Mental Ill-health and Violence: in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) www.foresight.gov.uk/Mental%20Capital/SR-B11_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-B11_MCW.pdf
 
Description Caspi and Moffitt - Monozygotic twin discordance - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on Monozygotic twin discordance in methylation level at 2 CpG sites was cited in the Government office for Science Foresight Project's State of Science Review on the Neurobiology of Well-being: A Life-Course Perspective in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-X3_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-X3_MCW.pdf
 
Description Caspi and Moffitt - adolescent-onset cannabis use and adult psychosis - UK Office of Science and Technology's Foresight Brain Science, Addiction and Drugs Project report
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research on the effect of adolescent-onset cannabis use on adult psychosis was cited in the UK Office of Science and Technology's Foresight Brain Science, Addiction and Drugs Project report "GENOMICS" http://www.foresight.gov.uk/Brain%20Science/Genomicsa.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-B14_MCW.pdf
 
Description Caspi and Moffitt - adolescent-onset cannabis use and psychosis - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the effect of adolescent-onset cannabis use on adult psychosis was cited in the Government office for Science Foresight Project's State of Science Review on the Influence of Social, demographic and physical factors on Substance abuse in all age groups in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-B14_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-B14_MCW.pdf
 
Description Caspi and Moffitt - childhood and adolescent-onset antisocial conduct problems - UK Home Office Research, Development and Statistics Directorate
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research on childhood-onset and adolescent-onset antisocial conduct problems in males was cited in the UK Home Office Research, Development and Statistics Directorate Findings Report 282 "Anti-social and other problem behavior among young children: Patterns and associated child characteristics" (2008) http://www.homeoffice.gov.uk/rds/pdfs08/r282.pdf
URL http://www.homeoffice.gov.uk/rds/pdfs08/r282.pdf
 
Description Caspi and Moffitt - childhood behavioral observations predicting adult psychiatric disorders - Hackney Council Youth and Crime Report
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in systematic reviews
Impact Research on behavioral observations of 3yr olds predicting adult psychiatric disorders and the research on violence between intimate partners and their effect on child psychologists/psychiatrists were both used in the Hackney Council's Children and Young People Scrutiny Commission's Youth and Crime Report for 2007-08, "Youth and Crime in Hackney: Prevention and Early Intervention" (7 April 2008) www.hackney.gov.uk/youth-and-crime-report-0708.pdf
URL http://www.hackney.gov.uk/youth-and-crime-report-0708.pdf
 
Description Caspi and Moffitt - conduct disorder and juvenile delinquency - UK Youth Justice Board
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research included in the book Causes of conduct disorder and juvenile delinquency was cited by the UK Youth Justice Board for England and Wales in their document on "Offending Behavior Programmes" (2008) http://www.yjb.gov.uk/publications/Resources/Downloads/Final%20OBP%20source.pdf
URL http://www.yjb.gov.uk/publications/Resources/Downloads/Final%20OBP%20source.pdf
 
Description Caspi and Moffitt - genotyping and the cycle of violence - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the role of genotype in the cycle of violence in maltreated children was cited in the Government office for Science Foresight Project's State of Science Review on the Neural Basis of Resilience in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) www.foresight.gov.uk/Mental%20Capital/SR-E7_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-E7_MCW.pdf
 
Description Caspi and Moffitt - genotyping and violence - Office of Science and Technology's Foresight Brain Science, Addiction and Drugs Project report
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research on the role of genotype in the cycle of violence in maltreated children was cited in the UK Office of Science and Technology's Foresight Brain Science, Addiction and Drugs Project report "GENOMICS" http://www.foresight.gov.uk/Brain%20Science/Genomicsa.pdf
URL http://www.foresight.gov.uk/Brain%20Science/Genomicsa.pdf
 
Description Caspi and Moffitt - life stress and depression - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the influence of life-stress on depression was cited in the Government Office for Science Foresight Project's State of Science Review on the Genetics of Ill-Health in Children and Adults and Interaction of Genes with Social Factors in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-B1_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-B1_MCW.pdf
 
Description Caspi and Moffitt - life stress and depression - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the influence of life-stress on depression was cited in the Government office for Science Foresight Project's State of Science Review on the Neural Basis of Resilience in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) www.foresight.gov.uk/Mental%20Capital/SR-E7_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-E7_MCW.pdf
 
Description Caspi and Moffitt - measuring interactions between genes and environments - UK Office of Science and Technology's Foresight Brain Science, Addiction and Drugs Project repor
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research on the strategy for measuring interactions between measured genes and measured environments was cited in the UK Office of Science and Technology's Foresight Brain Science, Addiction and Drugs Project report "GENOMICS" http://www.foresight.gov.uk/Brain%20Science/Genomicsa.pdf
URL http://www.foresight.gov.uk/Brain%20Science/Genomicsa.pdf
 
Description Caspi and Moffitt - origins of child and adolescent behavior problems - UK Home Office Online Report
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research on temperamental origins of child and adolescent behavior problems was cited in the UK Home Office Online Report "Anti-social and other problem behaviors among young children: Findings from the Avon Longitudinal Study of Parents and Children" (Feb 2008) http://www.homeoffice.gov.uk/rds/pdfs08/rdsolr0208.pdf
URL http://www.homeoffice.gov.uk/rds/pdfs08/rdsolr0208.pdf
 
Guideline Title The "Family - Nurse Partnership": developing an instrument for identification, assessment and recruitment of clients
Description Caspi and Moffitt - predictors of violent and non-violent criminal convictions - UK DCSF
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in clinical guidelines
Impact Research on temperamental and familial predictors of violent vs. non-violent criminal convictions was cited in the Research report DCSF-RW022 for the Dept. for Children, School and Families, "The "Family - Nurse Partnership": developing an instrument for identification, assessment and recruitment of clients" (October 2007). http://www.dcsf.gov.uk/research/data/uploadfiles/DCSF-RW022.pdf
URL http://www.dcsf.gov.uk/research/data/uploadfiles/DCSF-RW022.pdf
 
Description Caspi and Moffitt - theory of personality coherence - UK Youth Justice Board
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on the theory of personality coherence was cited by the UK Youth Justice Board for England and Wales in their document on "Assessment, Planning Interventions and Supervision" (2008) http://www.yjb.gov.uk/publications/Resources/Downloads/APISsource_final.pdf
URL http://www.yjb.gov.uk/publications/Resources/Downloads/APISsource_final.pdf
 
Description Caspi and Moffitt -personality coherence - UK DCSF Research Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the theory of personality coherence was cited in the UK Department for Education and Skills' Research report for the Department of Children, School and Families, "Preventing Children's Involvement in Crime and Anti-Social Behaviour: A Literature review" (2005) http://www.dcsf.gov.uk/research/data/uploadfiles/RR623.pdf
 
Description Collier - substance misuse - UK Office of Science and Technology
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research on Substance misuse in P. McGuffin's book Psychiatric Genetics and Genomics" was cited in the UK Office of Science and Technology's Foresight Brain Science, Addiction and Drugs Project report "GENOMICS" http://www.foresight.gov.uk/Brain%20Science/Genomicsa.pdf
URL http://www.foresight.gov.uk/Brain%20Science/Genomicsa.pdf
 
Description Contribution to policy document for NAS 'Getting on: growing older with autism'
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL http://www.autism.org.uk/gettingon
 
Description Craig - MZ twin discordance in methylation level - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on Monozygotic twin discordance in methylation level at 2 CpG sites was cited in the Government office for Science Foresight Project's State of Science Review on the Neurobiology of Well-being: A Life-Course Perspective in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-X3_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-X3_MCW.pdf
 
Description D'Souza - dopamine receptor gene - Office of Science and Technology
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research on indentifying polymorphisms in the dopamine receptor gene was cited in the UK Office of Science and Technology report from the Foresight Brain Science, Addiction and Drugs project, "Neuroscience and Drugs of Addiction" (2008) http://www.foresight.gov.uk/Brain%20Science/Neuroscience.pdf
URL http://www.foresight.gov.uk/Brain%20Science/Neuroscience.pdf
 
Description DSM-5 Autism Spectrum Disorder text - Happe
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact Responsible for drafting text for new ASD criteria. Reflect impact of our research, e.g. severity ratings will be made separately for social and nonsocial festures of ASD, as a result of our research on the 'fractionable triad'.
 
Description DSM-V Workgroup on Neurodevelopmental Disorders: invited member of this workgroup devising diagnostic criteria for autism and related disorders; one of only two Europeans among the 12 workgroup members.
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact This workgroup is reponsible for devising, drafting and assessing the new criteria for autism and related disorders in the APA's DSM-V, to be published in 2012/13. DSM-V will have a major impact on clinical care and research practice.
 
Description Genetics and the Future Diagnosis of Learning Disabilities contribution to Government Office for Science Foresight document on Mental Capital and Well-being
Geographic Reach National 
Policy Influence Type Participation in advisory committee
Impact MRC programme grant funding for the Twins Early Development Study (TEDS) since 1995 has produced the largest genetic study by far on learning abilities and disabilities with extensive data obtained for more than 5000 pairs of UK twins born 1994-96 at 2, 3, 4, 7, 9, 10, 12 and 14 years. TEDS has had a significant impact on the field of education which has previously been slow to accept genetics as documented in publications in education journals. ; A recent concrete sign of this impact is the central role genetics plays in the Government Office for Science Foresight document on Mental Capital and Well-being, which was launched in October 2008. Principal investigator was commissioned to review genetics and the future diagnosis of learning disabilities and his review was included as a chapter in the Foresight document.
 
Description Happe - Autism and Theory of mind - UK Wiltshire County Council's instructional document for the secondary school teachers
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
Impact Research on autism and moving beyond a theory of mind was cited in the UK Wiltshire County Council's instructional document for the secondary school teachers, "Secondary teacher's Toolkit for including Young People with Social Communication Difficulties (including Autism Spectrum Disorders and Asperger Syndrome)" (Sept 2006) www.wiltshire.gov.uk/secondary-scd-toolkit-photocopy-version.pdf
URL http://www.wiltshire.gov.uk/secondary-scd-toolkit-photocopy-version.pdf
 
Description Happe - Invited Member for DSM-V
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact Dr Happe is an invited member of the DSM-5 Neurodevelopmental Disorders Workgroup (2008-). It is responsible for drafting new Autism Spectrum Disorders text to accompany criteria.
 
Description Happe - National Autistic Society
Geographic Reach National 
Policy Influence Type Participation in advisory committee
Impact Prof Happe is serving asthe National Autistic Society's 'Autism in Maturity' Advisory Group member (2011-).
 
Description Invited member of NAS Advisory Committee on Autism in Maturity
Geographic Reach National 
Policy Influence Type Participation in advisory committee
 
Description Jaffee - CDC working group
Geographic Reach North America 
Policy Influence Type Membership of a guidance committee
Impact Dr Jaffee serves as a member of the Centers for Disease Control (CDC) working group. This group at the CDC commission basic research on factors that break the cycle of violence in families where parents have a history of maltreatment.
 
Description Jaffee - Commissioner for the Administration for Children and Families (US Govt)
Geographic Reach North America 
Policy Influence Type Gave evidence to a government review
Impact The Commissioner for the Administration for Children and Families (which oversees child welfare services in the USA) organised a special meeting to investigate how neuroscience can inform research, and the benefits of intervention with maltreated children and children in foster care. Dr Jaffee was invited to give a speacial presentation at the meeting.
 
Description Jaffee -genetically mediated child effects - U.S.A. National Children's Study Research Plan
Geographic Reach North America 
Policy Influence Type Influenced training of practitioners or researchers
Impact research on the limits of child effects and the genetically mediated child effects on corporal punishment was cited by the U.S.A. National Children's Study Research Plan in their article on "Repeated Mild Traumatic Brain Injury and Neurocognitive development" (Sept 2007) http://www.nationalchildrensstudy.gov/research/studydesign/researchplan/Pages/Appendix%20A-2%20Injury%20031808.pdf.
URL http://www.nationalchildrensstudy.gov/research/studydesign/researchplan/Pages/Appendix%20A-2%20Injur...
 
Description Kuntsi - genetic factors in the psychological mechanisms of hyperactivity - Committee on Toxicity report to UK Food Standards Agency and DoH
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the role of genetic factors in the psychological mechanisms of hyperactivity was cited in the Committee on Toxicity of chemicals in food, consumer products and the Environment (COT) statement of research project T07040 to the UK Food Standards Agency and the Department of Health, entitled "Investigating the effect of mixtures of certain food colours and a preservative on behavior in children" (2007) http://cot.food.gov.uk/pdfs/tox200714
URL http://cot.food.gov.uk/pdfs/tox200714
 
Description Kuntsi - genetic factors in the psychological mechanisms of hyperactivity - UK Committees on Toxicity, Mutagenicity, Carcinogenicity of Chemicals in Food, Consumer Products and the Environment
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research on the role of genetic factors in the psychological mechanisms of hyperactivity was cited by the Committees on Toxicity, Mutagenicity, Carcinogenicity of Chemicals in Food, Consumer Products and the Environment in their "Annual Report 2007" (June 2008) http://www.iacoc.org.uk/publications/documents/cotcomcocannualrep2007.pdf
URL http://www.iacoc.org.uk/publications/documents/cotcomcocannualrep2007.pdf
 
Description Maughan - 1979 to 2002 school effectiveness findings - Scottish Government
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on school effectiveness findings between 1979 and 2002 was cited by the Scottish Government's "Class Sizes, Staffing and Resources Working Group: Interim Report" (June 2006) http://www.scotland.gov.uk/Publications/2006/06/26102419/0
URL http://www.scotland.gov.uk/Publications/2006/06/26102419/0
 
Description Maughan - Conduct disorder and oppositional defiant disorder - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on conduct disorder and oppositional defiant disorder, and on time-trends in adolescent mental health were all cited in the Government office for Science Foresight Project's State of Science Review on Conduct disorder and antisocial behavior in the under-fives in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D8_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D8_MCW.pdf
 
Description Maughan - Long term outcome of reading problems - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the long-term outcomes of reading problems was cited in the Government office for Science Foresight Project's State of Science Review on Dyslexia in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) www.foresight.gov.uk/Mental%20Capital/SR-D2_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D2_MCW.pdf
 
Description Maughan - UK DoH Policy Research
Geographic Reach National 
Policy Influence Type Participation in advisory committee
Impact Prof B Maughan is a member of the Commissioning Panel for the UK Goverment's Department of Health's Policy Research Programme
 
Guideline Title Improving Access to Psychological Therapies (IAPT) Commisioning Toolkit
Description Maughan - financial costs of antisocial children - UK Dept of Health
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
Impact Research on followup studies of financial costs of antisocial children into adulthood was cited by the Care Services Improvement Partnership for the UK Dept of Health in the document "Improving Access to Psychological Therapies (IAPT) Commisioning Toolkit" (April 2008) http://www.icn.csip.org.uk/_library/IAPT_commissioning_toolkit.pdf
URL http://www.icn.csip.org.uk/_library/IAPT_commissioning_toolkit.pdf
 
Description Maughan - financial costs of antisocial children - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on followup studies of financial costs of antisocial children into adulthood was cited in the Government office for Science Foresight Project's State of Science Review on Mental Ill-Health: Cost Implications in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-B8_MCW.pdf
URL http://www.icn.csip.org.uk/_library/IAPT_commissioning_toolkit.pdf
 
Description McGuffin - heritability of social cognitive skills - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on heritability of social cognitive skills was cited in the Government office for Science Foresight Project's State of Science Review on Social cognition and school exclusion in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D9_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D9_MCW.pdf
 
Description McGuffin - mood induction in euthymic bipolar subjects - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on positive mood induction in euthymic bipolar subjects was cited in the Government office for Science Foresight Project's State of Science Review on the Neural basis of Resilience in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-E7_MCW.pdf.
URL http://www.foresight.gov.uk/Mental%20Capital/SR-E7_MCW.pdf
 
Guideline Title Assessment of Children in Need and their Families: Practice Guidance
Description McGuffin - self assessment of irritability - Wales Home Office Dept of Health and Social Services
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in clinical guidelines
Impact Research on the self assessment of irritability was cited in the National Assembly for Wales Home Office Dept of Health and Social Services document "Assessment of Children in Need and their Families: Practice Guidance" http://new.wales.gov.uk/dhss/publications/children/childrenfirst/606358/facnf-practiceguidance-20011.pdf?lang=en
URL http://www.crin.org/docs/assessing%20children%20in%20need%20and%20their%20families-%20practice%20gui...
 
Description McGuffin - serotonin transporter gene and environmental adversity - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the review and methodological analysis of the moderation by the serotonin transporter gene on environmental adversity was cited in the Government office for Science Foresight Project's State of Science Review on the Genetics of Ageing, Mental Ill health and Dementia in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-B12_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-B12_MCW.pdf
 
Description National Forum for Neuroscience and Special Education - Happe
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact The National Forum for Neuroscience and Special Education was created and co-developed by Francesca Happe. The Forum will provide a platform for neuroscientists and teachers in Special Education to engage in dialogue. It will encourage discourse around the changing pattern of childhood disability and share insights from both fields which will evolve innovative practice, leading to improved learning outcomes for children. The Forum will hold an annual national conference, and a regional seminar series.
 
Description Parliamentary Commission presentation (Autism and ageing, 11th March, 2013)
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
 
Description Plomin - EAS temperament scale research - UK Home Office Online report
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Research on the EAS temperament scale was cited by the UK home office in their online report "Anti-social and other problem behaviors among young children: Findings from the Avon Longitudinal study of Parents and Children" (Feb 2008) http://www.homeoffice.gov.uk/rds/pdfs08/rdsolr0208.pdf
URL http://www.homeoffice.gov.uk/rds/pdfs08/rdsolr0208.pdf
 
Description Plomin - Microarrays - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on Microarrays was cited in the Government office for Science Foresight Project's State of Science Review on Genetics and Future Diagnostics of Learning Disabilities in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-B11_MCW.pdf
 
Description Plomin - QTL scans and early reading disability - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on QTL association scan of early reading disability was cited in the Government office for Science Foresight Project's State of Science Review on Genetics and Future Diagnostics of Learning Disabilities in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
 
Description Plomin - children in the same family being different - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on why children in the same family are different was cited in the Government office for Science Foresight Project's State of Science Review on Genetics and Future Diagnostics of Learning Disabilities in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
 
Description Plomin - generalist genes and mathematicians -Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on generalist genes and mathematicians was cited in the Government office for Science Foresight Project's State of Science Review on Dyscalculia in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D4_MCW.PDF.
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D4_MCW.PDF
 
Description Plomin - genetic and environmental origins of learning disabilities - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the genetic and environmental origins of learning disabilities was cited in the Government office for Science Foresight Project's State of Science Review on Genetics and Future Diagnostics of Learning Disabilities in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
 
Description Plomin - genetic basis of complex behaviors - office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the genetic basis of complex behaviors was cited in the Government office for Science Foresight Project's State of Science Review on Genetics and Future Diagnostics of Learning Disabilities in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
 
Description Plomin - genetic contributions to the home environment -Dept of Education and Skills report
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact The research on cognitive and temperamental mediators of genetic contributions to the home environment during infancy was cited by the Dept of Education and Skills report to the Equalities Review, entitled "Promoting Equality in the Early Years " (Feb 2007) http://archive.cabinetoffice.gov.uk/equalitiesreview/upload/assets/www.theequalitiesreview.org.uk/promoting_equality_in_the_early_years.pdf
URL http://archive.cabinetoffice.gov.uk/equalitiesreview/upload/assets/www.theequalitiesreview.org.uk/pr...
 
Description Plomin - genetics and educational psychology - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on genetics and educational psychology was cited in the Government Office for Science Foresight Project's State of Science Review on Genetics and Future Diagnostics of Learning Disabilities in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf.
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D4_MCW.PDF
 
Description Plomin - genetics and environmental factors - Connexions service Diploma Reader
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on genetics and environmental factors was cited by the Connexions service in the UK in their Diploma Reader for Personal Advisers "Understanding Young People's Behavior: A Reader" www.connexions.gov.uk/partnerships/documents/Cnutm_r3.pdf
URL http://www.connexions.gov.uk/partnerships/documents/Cnutm_r3.pdf
 
Description Plomin - genetics findings - NHS Fife Dementia Strategy Open University
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact Thr research on opportunities for psychiatry from Genetic findings was cited in the NHS Fife Dementia Strategy Open University Chunk course K272_1 "Challenging Ideas in Mental Health" (2008) http://socialwork.fife.gov.uk/fds/mod/resource/view.php?id=245
 
Description Plomin - implications of generalist genes - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the implications of generalist genes was cited in the Government office for Science Foresight Project's State of Science Review on Genetics and Future Diagnostics of Learning Disabilities in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf.
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
 
Description Plomin - links between brain, mind and education - office for Science Foresight Project's State of Science Review
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in systematic reviews
Impact Research on genetic links between brain, mind and education was cited in the Government office for Science Foresight Project's State of Science Review on Genetics and Future Diagnostics of Learning Disabilities in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf.
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D4_MCW.PDF
 
Description Plomin - parental feeding style - Peterborough Council strategy policy
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on parental feeding style was cited in the Peterborough Council strategy policy document "Healthy Weight Peterborough: Achieving a Healthy Weight Community in Greater Peterborough. A Strategy for the Prevention and Management of Overweight and Obesity" (2006) https://www.peterborough.gov.uk/PDF/counc-policies-cypp-pboro-healthy-weight-strategy.pdf
URL https://www.peterborough.gov.uk/PDF/counc-policies-cypp-pboro-healthy-weight-strategy.pdf
 
Description Plomin - stable genetic influences on learning - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on substantial and stable genetic influences on learning was cited in the Government office for Science Foresight Project's State of Science Review on Genetics and Future Diagnostics of Learning Disabilities in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf.
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D7_MCW.pdf
 
Description Plomin - temperament and early developing personality traits - Scottish Govt Review of Childcare and the Development of Children
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in systematic reviews
Impact Research on temperament and early developing personality traits was cited in the Scottish govt Review of Childcare and the Development of Children Aged 0-3: Research Evidence, and Implications for Out-of-Home Provision, entitled "Supporting a Young Child's Need for Care and Affection, Shared Meaning and a Social Place" http://www.scotland.gov.uk/Resource/Doc/933/0007610.pdf
URL http://www.scotland.gov.uk/Resource/Doc/933/0007610.pdf
 
Description Plomin - young children's cognitive development - Welsh Dept of Work and Pensions
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on environmental risk and young children's cognitive development was cited in the Welsh Public Health Strategy Division of the Dept of Public Health and Health Professions' Executive Summary article "National Health Targets for Child Health: Social Determinants for Child Health"(March 2008) http://new.wales.gov.uk/dphhp/publication/research/health-gain-targets/child/childhealth-fullexec.pdf?lang=en.
 
Description Plomin -genetic and environmental influences on academic performance- Norfolk Govt Children's Services Briefing paper
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on the twin studies into genetic and environmental influences on academic performance was cited by the Norfolk Govt Children's Services Central Area paper, "Educational Psychology and Specialist Support Research Briefing paper for Schools, Settings and Services" (1 March 2008) http://www.esinet.norfolk.gov.uk/cadmin/files/cResearch%20Briefing.pdf.
URL http://www.esinet.norfolk.gov.uk/cadmin/files/cResearch%20Briefing.pdf
 
Description Price - behavior problems and verbal and nonverbal disabilities - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the association between behavior problems and verbal and nonverbal disabilities in early childhood was cited in the Government Office for Science Foresight Project's State of Science Review on Social Cognition and School Exclusion in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D9_MCW.pdf.
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D9_MCW.pdf
 
Description Price - environmental risk and young children's cognitive development - Welsh Dept of Public Health and Health Professions
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on environmental risk and young children's cognitive development was cited in the Welsh Public Health Strategy Division of the Dept of Public Health and Health Professions' Executive Summary article "National Health Targets for Child Health: Social Determinants for Child Health"(March 2008) http://new.wales.gov.uk/dphhp/publication/research/health-gain-targets/child/childhealth-fullexec.pdf?lang=en.
URL http://new.wales.gov.uk/dphhp/publication/research/health-gain-targets/child/childhealth-fullexec.pd...
 
Description Rutter - "Fifteen Thousand Hours"- Association of Teachers and Lecturers N. Ireland
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
Impact research in the book Fifteen Thousand Hours was cited by Association of Teachers and Lecturers in their response to the 2007 Education Mandate in the Northern Ireland Assembly "Response to Education Committee Request for Views on The Minister of Education's proposal of 15th May 2008 for Transfer to Post Primary Education from 2010)" (2007) http://www.niassembly.gov.uk/education/2007mandate/responses/atl.htm
 
Description Rutter - Antisocial Behavior by Young People - Wales government Flying Start Parenting Programme
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
Impact Research in the book Antisocial Behavior by Young People was used by the Wales government Flying Start Parenting Programmes in their document "Flying Start Guidance - Annex C" http://wales.gov.uk/dcells/publications/policy_strategy_and_planning/early-wales/flyingstart/fsannexc.pdf?lang=en
URL http://wales.gov.uk/dcells/publications/policy_strategy_and_planning/early-wales/flyingstart/fsannex...
 
Description Rutter - family and school influences on cognitive development - Northamptonshire Joint Strategic Needs Assessment
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on family and school influences on cognitive development was cited as part of the official "Northamptonshire Joint Strategic Needs Assessment" (2008) http://www3.northamptonshire.gov.uk/NR/rdonlyres/963A5B65-5211-4E1A-BAC0-B660066E0677/0/JSNA2008Bibliography.pdf
URL http://www3.northamptonshire.gov.uk/NR/rdonlyres/963A5B65-5211-4E1A-BAC0-B660066E0677/0/JSNA2008Bibl...
 
Description Rutter - individual characteristics and development - Scottish Government publication
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on individual characteristics as a force for development was cited in the Scottish Government publication "Celebrating Success: What Helps Looked After Children Succeed" (June 2006) http://www.scotland.gov.uk/Publications/2006/06/07121906/12
URL http://www.scotland.gov.uk/Publications/2006/06/07121906/12
 
Description Rutter - parents with children in care -London Safeguarding Children Board
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
Impact research on parents with children in care was used in the UK Government's London Safeguarding Children Board conference document on the Young Carers Programme, entitled "Young Carers, young Victims, or young Survivors?: impacts on, and responses of children of parents with mental illness" (2008) http://www.londonscb.gov.uk/files/conference08/cooklin__young_carers.pdf.
URL http://www.londonscb.gov.uk/files/conference08/cooklin__young_carers.pdf
 
Description Rutter - protective factors and resilience to psychiatric discorders - Scottish Government publication
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on protective factors and resilience to psychiatric discorders was cited in the Scottish Government publication "Celebrating Success: What Helps Looked After Children Succeed" (June 2006) http://www.scotland.gov.uk/Publications/2006/06/07121906/12
URL http://www.scotland.gov.uk/Publications/2006/06/07121906/12
 
Description Rutter - women institutionalized in childhood in long term social life - Scottish Government publication
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on women institutionalized in childhood and the long-term factors promoting good functioning in social life was cited in the Scottish Government publication "Celebrating Success: What Helps Looked After Children Succeed" (June 2006) http://www.scotland.gov.uk/Publications/2006/06/07121906/12
URL http://www.scotland.gov.uk/Publications/2006/06/07121906/12
 
Description Rutter -research on Maternal Deprivation, Reassessed - Scottish Government publication
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in systematic reviews
Impact Research in the book Maternal Deprivation Reassessed was cited in the Scottish Government publication "The Effectiveness of Interventions to Address Health Inequalities in the Early Years: A Review of Relevant Literature" (July 2008) http://www.scotland.gov.uk/Publications/2008/07/08102811/11
URL http://www.scotland.gov.uk/Publications/2008/07/08102811/11
 
Description Rutter Parents' and Teachers' Scales - UK DFES summary document National Teacher Research Panel
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on the use and development of the Rutter Parents' and Teachers' Scales was cited by the UK DFES in their information and summary document for the National Teacher Research Panel at the Teacher Research Conference 2006 "Visual Awareness Strategy" (2006) http://www.standards.dfes.gov.uk/ntrp/lib/pdf/myers.pdf
URL http://www.standards.dfes.gov.uk/ntrp/lib/pdf/myers.pdf
 
Description Schumann - condition on serotonin transporter genotype 5-HTTLPR - Office for Science Foresight Project's State of Science Review
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Research on the effects of neutral and undefined condition on serotonin transporter genotype 5-HTTLPR was cited in the Government Office for Science Foresight Project's State of Science Review on Depression in Childhood and Adolescence in "Mental Capital and Well-Being: Making the Most of Ourselves in the 21st Century" (Sept 2008) http://www.foresight.gov.uk/Mental%20Capital/SR-D15_MCW.pdf.
URL http://www.foresight.gov.uk/Mental%20Capital/SR-D15_MCW.pdf
 
Description Secondary schools and their effects on children - UK DCSF Document for OISE
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research in the book Fifteen thousand hours: Secondary schools and their effects on children was cited in the UK Dept for Children, School and Families document by the Ontario Institute for Studies in Education (OISE) in the 3rd Annual report for the project "Watching and Learning" http://www.standards.dfes.gov.uk/primary/publications/literacy/63525/
URL http://www.standards.dfes.gov.uk/primary/publications/literacy/63525/
 
Description Taylor - Establishing EU guidelines on managing adverse effects of ADHD medication
Geographic Reach Asia 
Policy Influence Type Participation in advisory committee
Impact Academics from the Institute of Psychiatry (IoP) at King's - including Prof Eric Taylor, Professor of Child & Adolescent Psychiatry at the MRC SGDP Centre - have taken a leading part in shaping EU guidelines on managing adverse effects of medication for attention deficit hyperactivity disorder (ADHD). The safety of ADHD medications is not fully known and concerns have arisen about a lack of contemporary-standard information about medications first licensed several decades ago. Professors
 
Description Taylor - Hidradenitis Suppurativa Foundation, Knowledge Database
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact research on Anaerobic axillary abscesses was cited as part of the knowledge database that was created, used and is referenced by the Hidradenitis Suppurativa Foundation, Inc. (HSF), which is dedicated to improving the quality of life and quality of care for individuals and families affected by Hidradenitis Suppurativa (HS). The research is included in the HSF FTP HS Research Database Content List, which empowers and facilitates varying degrees of direct patient support by providing information to government, legal, health and social service organizations, as well as patient advocacy/self-help and support groups around the world. (2007) http://www.hs-foundation.org/research/database.htm
URL http://www.hs-foundation.org/research/database.htm
 
Guideline Title CG72 Full ADHD Guideline Appendices 11-16
Description Taylor - NICE UK - Full ADHD Guideline
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
Impact research on Hyperkineses and ADHD was cited by the National Health Service's National Institute for Clinical Excellence (NICE) UK in the appendices of their guidelines for ADHD treatment, entitled "CG72 Full ADHD Guideline Appendices 11-16" (Sept 2008) http://www.nice.org.uk/nicemedia/pdf/CG72FullGuidelineAppendices11-16.pdf
URL http://www.nice.org.uk/nicemedia/pdf/CG72FullGuidelineAppendices11-16.pdf
 
Guideline Title National Institute for Health and Clinical Excellence: Attention deficit hyperactivity disorder scope - stakeholder consultation table - College of Occupational Therapists
Description Taylor - NICE UK ADHD Guidelines consultation table
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
Impact research on the treatment of hyperkinetic disorders in children was cited by the National Health Service's National Institute for Clinical Excellence (NICE) UK, in their document, "National Institute for Health and Clinical Excellence: Attention deficit hyperactivity disorder scope - stakeholder consultation table - College of Occupational Therapists" (Feb 2006) http://www.nice.org.uk/nicemedia/pdf/ADHD_Consultationtable.pdf
URL http://www.nice.org.uk/nicemedia/pdf/ADHD_Consultationtable.pdf
 
Description Trustee for the Human Genome Organisation (HUGO) - I Craig
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact Prof Ian Craig is the trustee for the Human Genome Organisation (HUGO) and Acting Chair of the HUGO Education Committee. He has the responsibility for promoting science education in sub Saharan African Universities.
 
Description predictors of violent vs. non-violent criminal convictions - UK Cabinet Office Report
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
Impact Research on temperamental and familial predictors of violent vs. non-violent criminal convictions was cited in the Cabinet Office Report to the UK Dept. of Health and Prime Minister's Strategy Unit "" (2007). http://www.cabinetoffice.gov.uk/~/media/assets/www.cabinetoffice.gov.uk/strategy/anti%20social%20pdf.ashx
URL http://www.cabinetoffice.gov.uk/~/media/assets/www.cabinetoffice.gov.uk/strategy/anti%20social%20pdf...
 
Description "MiND - Mastering skills in the training Network for attention deficit hyperactivity and autism spectrum Disorders" ( Jonna Kuntsi Philip Asherson)
Amount £376,043 (GBP)
Funding ID 643051 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 01/2015 
End 12/2018
 
Description A Bayesian network model of gene expression,genotype and phenotype in the psychosis of Alzheimer's disease
Amount £144,516 (GBP)
Funding ID ART-RF2007-3 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description A Genome association study of Unipolar depression and Initial exploration of functional Allelic Variation
Amount £1,168,363 (GBP)
Funding ID G0701420 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description A MRI study on a sub-sample of the GENDEP human Pharmacogenomics study
Amount £102,558 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description A blood test for Alzheimer's disease (Computational approaches to identify Alzheimer's disease progression biomarkers and evaluate their performance)
Amount £49,500 (GBP)
Organisation Rosetrees Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description A double-blind, placebo-controlled study of neural correlates of depression following antidepressant treatment
Amount £800 (GBP)
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description A feasibility study of different device parameters for the management of patients with treatment resistant major depressive disorder, single or recurrent episode, with deep brain stimulation (McGuffin, Farmer, Abdelghani)
Amount £70,680 (GBP)
Funding ID NM-09-035-EU-DB 
Organisation St. Jude Medical 
Sector Private
Country United States
Start 09/2011 
End 08/2013
 
Description A genome wide association study of the relationship between body mass index (BMI), type II diabetes and recurrent depression" EU Marie Curie Fellowship for Dr Margarita Rivera Sanchez
Amount £126,718 (GBP)
Funding ID 236858 
Organisation Marie Sklodowska-Curie Actions 
Sector Charity/Non Profit
Country Global
Start  
 
Description A genome wide association study of unipolar depression
Amount £1,178,240 (GBP)
Funding ID G0701420 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2008 
End 01/2010
 
Description A genome-wide scan for novel imprinted loci
Amount £14,986 (GBP)
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description A multi-faceted approach to identifying epigenomic dyfusion in Alzheimer's disorder and associated neuropsychiatric co-morbidities: discovering epigenetic biomarkers in brain tissue and peripheral blood
Amount £545,266 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description A multi-faceted approach to identifying epigenomic dyfusion in Alzheimer's disorder and associated neuropsychiatric co-morbidities: discovering epigenetic biomarkers in brain tissue and peripheral blood
Amount £278,838 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description A multi-site study of the genetics of child anxiety and predictors of treatment response
Amount £497,564 (GBP)
Funding ID G0901874 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description ADAMS Genomic variations underlying common neuropsychiatric diseases and disease-related cognitive traits in different human populations (3m euros across 12 participants)
Amount £191,070 (GBP)
Funding ID 242257 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description ADHD, an unmet need: increasing the recognition of behavioural problems associated with ADHD within St Andrews Healthcare
Amount £61,521 (GBP)
Organisation St. Andrew's Healthcare 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Adult outcomes and needs among high functioning individuals with autism spectrum disorders and their siblings
Amount £183,900 (GBP)
Organisation Nuffield Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Alicia Koplowitz Foundation Fellowship - E Taylor
Amount £118,005 (GBP)
Organisation Alicia Koplowitz Foundation 
Sector Charity/Non Profit
Country Spain
Start  
 
Description Alicia Koplowitz Foundation Fellowship - Taylor & Simonoff
Amount £124,669 (GBP)
Organisation Alicia Koplowitz Foundation 
Sector Charity/Non Profit
Country Spain
Start  
 
Description An fMRI Pilot study if the effects of cognitive behavioural therapy in bulimia nervosa: a strategy for translational research, SLAM NHS Trust
Amount £18,840 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description An imaging genomic investigation of major depressive disorder (MDD)
Amount £22,150 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description An investigation into Blood sampling of EFAs, Behavioural Questionnaries and Assessments of Brain Function in ADHD Participants and Healthy Matched Controls
Amount £15,450 (GBP)
Organisation Vion Pharmaceuticals 
Sector Private
Country United States
Start  
 
Description An investigation of replicated genetic associations from a genome - wide study of sporadic MNP
Amount £350,000 (GBP)
Funding ID G0600974 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Analytic infrastructure for the neuroimaging centre (South London and Maudsley NHS Foundation Trust)
Amount £39,509 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Antenatal depression and the epigenetics of developmental programming (Mill)
Amount £18,498 (GBP)
Funding ID 21/01/1953 
Organisation Brain & Behaviour Research Foundation 
Sector Charity/Non Profit
Country United States
Start 01/2013 
End 01/2015
 
Description Application of conformal predictors to functional magnetic resonance imaging
Amount £14,393 (GBP)
Funding ID G0802594 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Attentional Bias Modification: Development and testing of a school-based Cognitive Vaccine for the reduction and prevention of child anxiety (Eley - Lester)
Amount £240,869 (GBP)
Funding ID MR/J011762/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 08/2012 
End 07/2014
 
Description Autism Phenotypes in Tuberous Sclerosis: Risk Factors, Features & Architecture (Bolton)
Amount £82,714 (GBP)
Funding ID #7696 
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start 06/2012 
End 05/2015
 
Description Autism Spectrum and Attention Deficit Hyperactivity Disorders in Tuberous Sclerosis: Risk Factors, Features & Architecture (Bolton)
Amount £80,000 (GBP)
Funding ID 02/02/1955 
Organisation Tuberous Sclerosis Association 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2012 
End 08/2014
 
Description Autism genetics and normal variation in cognition and behavior
Amount £110,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Autism-spectrum disorders : treating co-morbid social anxiety disorder with adapted cognitive behaviour therapy Fellowship D Spain (Happe)
Amount £273,370 (GBP)
Funding ID CDRF-2012-03-059 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 06/2013 
End 05/2016
 
Description Autistica contribution to PhD studentships in mental health and autism. (Francesca Happe)
Amount £66,667 (GBP)
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2015 
End 09/2016
 
Description BRC - A new screening tool for the prediction of psychiatric adverse effects in patients receiving interferon-a treatment for chronic viral hepatitis C
Amount £75,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC - Genetic causes of Neurodevelopmental Delay in Children: translation and interpretation of novel pathogenic copy number variants and novel rare exonic mutations into clinical genetic practice
Amount £47,569 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC - Investigating Adverse Effects of Psychiatric Drugs through Data-Mining of Electronic Health Records and Integration of Clinical and Genomic Data (Dobson)
Amount £53,929 (GBP)
Organisation Guy’s & St Thomas’ Charity 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2013 
End 03/2014
 
Description BRC A study of blood-based markers of brain amyloid burden in monozygotic twins discordant for cognitive impairment (Kiddle)
Amount £40,000 (GBP)
Funding ID BRC EMCT Pilot Funding 
Organisation King's College London 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 11/2012 
End 03/2013
 
Description BRC Depression manager software
Amount £20,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC Gene expression profiling in the MRC Brain bank : a systems based biology approach to Dementia (Newhouse)
Amount £28,000 (GBP)
Funding ID BRC EMCT Pilot Funding 
Organisation King's College London 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 11/2012 
End 03/2013
 
Description BRC Project - Substance Use Disorders
Amount £962,588 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC Project - Substance Use Disorders
Amount £747,834 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC Pump Priming - An integrated framework to analyze genetic data of complex disorders
Amount £20,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC Theme: Biomedical Technologies
Amount £2,186,695 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC funding to extract parental DNA samples - Dr Eley
Amount £36,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC studentship for Charlotte Nymberg
Amount £48,120 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 10/2009 
End 09/2012
 
Description Baily Thomas Charitable Fund Project Grants
Amount £59,629 (GBP)
Organisation Baily Thomas Charitable Fund 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2012 
End 06/2014
 
Description Biological mechanisms underlying the onset and outcome of cannabis-associated psychosis (Marta Di Forti)
Amount £1,004,671 (GBP)
Funding ID MR/M008436/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2015 
End 12/2018
 
Description Biomedical Research Centre for Mental Health - EMCT Cluster - BioResource for Mental Health (Breen)
Amount £2,432,434 (GBP)
Funding ID SLAM NHS Trust EMCT Cluster 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2012 
End 03/2017
 
Description Biomedical Research Centre for Mental Health - EMCT Cluster - Biomarkers and genomics (Breen, Asherson, McGuffin)
Amount £1,402,802 (GBP)
Funding ID EMCT Cluster SLAM NHS Trust 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2012 
End 03/2017
 
Description Brain correlates of Childhood Maltreatment
Amount £396,082 (GBP)
Organisation Kids company 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Brain fitness: can we improve executive attention in children who were born very preterm (Francesca Happe)
Amount £119,985 (GBP)
Funding ID 14-15/33 
Organisation Newlife 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2015 
End 08/2017
 
Description British Academy Postdoctoral Fellowship (Haworth)
Amount £258,002 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start  
 
Description Building CNS focised Connectivity Maps of CNS drugs - Pilot Study
Amount £20,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Childhood trauma, inflammation and depression: a test of the biological embedding hypothesis
Amount £20,345 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start 01/2010 
End 12/2010
 
Description Cognitive-Neurophysiological markers in ADHD: a follow-up study of ADHD and control sibling pairs.
Amount £194,528 (GBP)
Funding ID 1777 
Organisation Action Medical Research 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Collection of control subjects for genetic studies from Ethiopia/Virginia Commonwealth University
Amount £10,000 (GBP)
Organisation Virginia Commonwealth University 
Sector Academic/University
Country United States
Start  
 
Description Colorado Adoption/Twin Study of Lifespan behavioural development and cognitive ageing (CATSLife) ( Robert Plomin)
Amount £42,192 (GBP)
Funding ID 1RO1AG046938 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2015 
End 02/2016
 
Description Combinatorial biomarkers for dementia prodromes, prediction, pathology and progression
Amount £715,000 (GBP)
Funding ID ART-PG2010-4 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Comorbid Conditions of Attention deficit / hyperactivity disorder [CoCA] ( Jonna Kuntsi Philip Asherson)
Amount £432,440 (GBP)
Funding ID 667302 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 01/2016 
End 12/2020
 
Description Comparative analysis of primate genomes, transcriptomes and proteomes with an emphasis on cognitive capabilities
Amount £317,277 (GBP)
Funding ID 28594 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Consortium on Vulnerability to Externalizing Disorders and Addictions [c-VEDA] (Gunter Schuman)
Amount £1,127,273 (GBP)
Funding ID MR/N000390/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2015 
End 10/2018
 
Description Contract with RGA UK Services
Amount £123,000 (GBP)
Organisation RGA UK Services Ltd 
Sector Private
Country United Kingdom
Start 10/2016 
End 09/2017
 
Description Contribution of genetics and early cognitive and emotional development to attention problems in middle childhood (Fellowship for Karla Holmboe)
Amount £193,914 (GBP)
Funding ID G0800054 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Copy number variations conferring risk of psychiatric disorders in children
Amount £428,526 (GBP)
Funding ID 223423 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Creating an early diagnostic test for Alzheimer's - transforming our ability to tackle the disease (Dobson)
Amount £79,457 (GBP)
Funding ID 171 
Organisation Alzheimer’s Society 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2013 
End 03/2016
 
Description DNA methylation and adolescent depression: an MZ differences study (Eley Dempster Mill)
Amount £47,800 (GBP)
Funding ID McGregor 97 
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start 09/2011 
End 08/2013
 
Description DTA Professor Anne Farmer
Amount £82,530 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2006 
End 09/2010
 
Description Defining the role of micro RNA regulation in neurotransmission
Amount £22,950 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description Defining the role of micro RNA regulation in neurotransmission BBSRC Industrial Partnership - CASE award
Amount £78,820 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description Dental Pain Study - assessment of ongoing pain using imaging and genetics
Amount £459,460 (GBP)
Organisation Pfizer Ltd 
Sector Private
Country United Kingdom
Start  
 
Description Designing a protocol to measure the developmental trajectory of infants with Tuberous Sclerosis (Charlotte Tye)
Amount £59,922 (GBP)
Funding ID 2015-F01 
Organisation Tuberous Sclerosis Association 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2015 
End 10/2016
 
Description Detecting inversion polymorphisms from SNP data (Paul O'Reilly)
Amount £97,799 (GBP)
Funding ID 109863/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2016 
End 09/2017
 
Description Developmental change in temperament in preschoolers: implications and etiology (Asherson)
Amount £5,734 (GBP)
Funding ID 1R01HD068435-01A1 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 04/2012 
End 01/2013
 
Description Developmental change in temperament in preschoolers: implications and etiology. (Philip Asherson)
Amount £3,682 (GBP)
Funding ID 5R01HD068435-04 Subaward: 4500000974 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 02/2015 
End 01/2016
 
Description Developmental cognitive disorders and transient gestational hypothyroidism (Cathy Fernandes)
Amount £79,047 (GBP)
Funding ID R151005 
Organisation King’s Health Partners 
Sector Academic/University
Country United Kingdom
Start 11/2015 
End 11/2016
 
Description Developmental pathways into adolescent substance abuse: neurophysiologic, genetic and environmental determinants
Amount £1,227,754 (GBP)
Funding ID G0901858 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Dissection of stress vulnerability through gene-environment interactions
Amount £220,428 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Does elevated C-reactive protein predict future psychopathology amongst children exposed to trauma? (Fisher)
Amount £15,652 (GBP)
Funding ID 164-1719 
Organisation The Waterloo Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2013 
End 02/2014
 
Description Dr Christian Muller - MRC Centre Studt - A. Easton
Amount £83,720 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Jonathan Mill - MRC Centre Studt- R. Pidsley
Amount £83,720 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Jonna Kuntsi - MRC DTA Studt - R. Pinto
Amount £89,428 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Leonard Schalkwyk - MRC GENE Studt- K. Malki
Amount £83,720 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Louise Arseneault - MRC DTA Studt - S. Shakoor
Amount £89,428 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Sara Jaffee - ESRC Studentship for L. Lysenko
Amount £79,520 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dyslexia genes and neurological pathways
Amount £85,206 (GBP)
Funding ID 18696 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description EC FP7 funding (Psych CNVs project, PB)
Amount £428,000 (GBP)
Funding ID 223423 
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start  
 
Description EC, Frame work 6 Integrated Project-Reinforcement-related behaviour in normal brain function and psychopathology
Amount £994,623 (GBP)
Funding ID 37286 
Organisation Sixth Framework Programme (FP6) 
Sector Public
Country European Union (EU)
Start  
 
Description ENIGMA Centre for Worldwide Medicine, Imaging and Genetics (Sylvane Desrivieres Gunter Schumann)
Amount £27,412 (GBP)
Funding ID 1U54EB020403-01 Subaward: 56999812 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2014 
End 05/2015
 
Description ENIGMA Centre for Worldwide Medicine, Imaging and Genetics (Sylvane Desrivieres)
Amount £38,337 (GBP)
Funding ID 1U54EB020403-01 Subaward: 65262849 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2015 
End 05/2016
 
Description ERC Advanced Investigator Grant
Amount £1,752,641 (GBP)
Organisation European Research Council (ERC) 
Sector Public
Country Belgium
Start  
 
Description ESRC 2009 SGDP - Andrew Merwood
Amount £80,910 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description ESRC 2009 SGDP - Elizabeth O'Nions
Amount £80,910 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description ESRC Post - Doctoral fellowship
Amount £83,218 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description ESRC-Physiological and cognitive mediators of gene x environment interaction effects on children's antisocial behaviour
Amount £866,016 (GBP)
Funding ID ES/G020132/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description EU FP6 Contract - APES - Comparative analysis of primate genomes, transcriptomes and proteomes with an emphasis on cognitive capabilities.
Amount £318,906 (GBP)
Funding ID 28594 
Organisation Sixth Framework Programme (FP6) 
Sector Public
Country European Union (EU)
Start  
 
Description Early adversity and psychotic experiences: bio-psycho-social pathways and resiliences (Helen Fisher Jonathan Mill)
Amount £225,000 (GBP)
Funding ID MQ14F40 
Organisation MQ Transforming Mental Health 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2015 
End 12/2017
 
Description Elucidating the aetiology of psychopathology: Taking a multigenerational approach to genetically informative data (Thomas McAdams)
Amount £706,162 (GBP)
Funding ID 107706/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2015 
End 08/2020
 
Description EpiTrain - Innovative techniques and models to understand epigenetic regulation in the pathogenesis of common diseases (Mill) EC Framework
Amount £248,954 (GBP)
Funding ID 316758 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 03/2013 
End 02/2017
 
Description Epidemiology of ADHD Pharmacological Treatments in Children and Adults in UK Primary Care
Amount £32,938 (GBP)
Organisation Shire Pharmaceuticals 
Department Shire Development
Sector Private
Country United States
Start  
 
Description Epidemiology of ADHD Pharmacological Treatments in Children and Adults in UK Primary Care/Shire Development INC
Amount £25,000 (GBP)
Organisation Shire Pharmaceuticals 
Department Shire Development
Sector Private
Country United States
Start  
 
Description Epigenetic and Transcriptional Dysregulation in Autism Spectrum Disorder. ( Jonathan Mill)
Amount £79,178 (GBP)
Funding ID 1R01MH094714-01 G PH276 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 07/2014 
End 06/2015
 
Description Epigenetic and Transcriptional Dysregulation in Autism Spectrum Disorder. (Mill)
Amount £125,582 (GBP)
Funding ID 1R01MH094714-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 08/2011 
End 06/2015
 
Description Epigenetic mechanisms of memory storage
Amount £131,550 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Epigenetic pathways to conduct problem trajectories: the role of prenatal and pos (J Mill)
Amount £205,515 (GBP)
Funding ID 1 R01 HD068437-01A1 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 02/2012 
End 01/2015
 
Description Epigenetic trajectories of biological response to adolescent psychosocial stress: A novel longitudinal study of discordant monozygotic twins (Chloe Wong Helen Fisher)
Amount £400,890 (GBP)
Funding ID ES/N000277/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 12/2015 
End 11/2018
 
Description Epigenetics of Alzheimer's disease
Amount £92,700 (GBP)
Funding ID ART-PhD2009-3 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Establishing the utility of pharmacogenetic prescribing in psychiatric disorders (C Lewis-Studentship) -M Verbelen
Amount £31,400 (GBP)
Organisation Eli Lilly & Company Ltd 
Sector Private
Country United Kingdom
Start 10/2013 
End 09/2017
 
Description Estimating risks of Schizophrenia across genetic and environmental factors Guys and St Thomas Charitable Foundation
Amount £258,014 (GBP)
Organisation Guy’s & St Thomas’ Charity 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description European Association of Personality Psychology travel scholarship
Amount £330 (GBP)
Organisation European Association of Personality Psychology (EAPP) 
Sector Charity/Non Profit
Country Netherlands
Start 01/2010 
End 12/2010
 
Description European Autism Interventions - A Multicentre Study for Developing New Medications (EU-AIMS) - Direct Funding Contribution from Autism Speaks (Schumann)
Amount £460,112 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start 04/2012 
End 03/2017
 
Description European Autism Interventions - a multicentre study for developing new medications (EU-AIMS) (Collier)
Amount £1,497,670 (GBP)
Funding ID 05/09/2215 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 04/2012 
End 03/2017
 
Description Evaluating a methology for the investigation into the effects of discontinuing stimulant medication in a controlled trial, South London and Maudsley (SLAM) Trust R&D
Amount £40,884 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Experimental study to explore potential brain activation changes in children with ADHD after one dose of Atomoxetine compared to Methylphenidate or Placebo children with attention Deficit Hyperactivity Disorder (ADHD)
Amount £40,000 (GBP)
Organisation Valspar 
Sector Private
Country United States
Start  
 
Description FP6 Specific Targeted Research Project - A Large Scale Genome-Wide Association Study of Schizophrenia Addressing Variation in Expressivity and Contribution from Environmental Factors (SGene)
Amount £279,485 (GBP)
Funding ID 37761 
Organisation Sixth Framework Programme (FP6) 
Sector Public
Country European Union (EU)
Start  
 
Description Familial transmission of emotional development: A children of twins approach
Amount £195,440 (GBP)
Organisation The Leverhulme Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Familial transmission of emotional development: A children of twins approach (Eley)
Amount £195,440 (GBP)
Funding ID RPG-210 
Organisation The Leverhulme Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2012 
End 02/2015
 
Description Fellowship in Mental Health Statistics with especial emphasis on genetics
Amount £135,422 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Financial support for FP7 application SGENeSIS
Amount £3,491 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Foundation Peters Research Grant
Amount £140,000 (GBP)
Organisation Hinrichsen Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2016 
End 08/2020
 
Description From genes to brain behavior: A multidisciplinary investigation of the autistic triad./National alliance for Autism research
Amount £41,669 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description Functional Correlates and Genetic Risk for Neuropsychiatric Traits Associated with Rolandic Epilepsy
Amount £99,906 (GBP)
Funding ID WF11 
Organisation Epilepsy Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description G1100583 - Low coverage sequencing for the detection and analysis of genomic structural variants in schizophrenia (Dobson)
Amount £1,015,920 (GBP)
Funding ID G1100583 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2011 
End 09/2014
 
Description GEnG*EED - Environment, genetics and endophenotypes in eating disorders and obesity
Amount £141,647 (GBP)
Funding ID 254774 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description GHCA: Genetics of High Cognitive Abilities (Plomin)
Amount £2,068,331 (GBP)
Funding ID 06/09/2708 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 04/2012 
End 03/2017
 
Description Gender Differences in Autism Spectrum Disorders in a Population-Based Twin Sample: testing three hypotheses for male preponderance.(Francesca Happe Emma Colvert)
Amount £540,514 (GBP)
Funding ID ES/M011488/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2016 
End 12/2018
 
Description Gene x gene and gene x environment interactions underlying speech, language and reading development - G0800523
Amount £6,099 (GBP)
Funding ID G0800523 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Gene-Environment Interplay in Children`s Resilience to Harsh, Non-Supportive Parenting
Amount £186,407 (GBP)
Organisation Nuffield Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Gene-environmental interactions in youth mental health visiting fellowship (Arseneault)
Amount £990,000 (GBP)
Funding ID NF120069 
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2014
 
Description Genetic analysis of rare and common variation in a large Brazilian bipolar family (BBFGEN) (Simone de Jong)
Amount £139,425 (GBP)
Funding ID 658195 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 05/2015 
End 04/2017
 
Description Genetic causes of Neurodevelopmental Delay in Children: translation and interpretation of novel pathogenic copy number variants and novel rare exonic mutations into clinical genetic practice
Amount £24,431 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Genetics of mathematical cognition and disabilities
Amount £410,156 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Genetics, school environment and cognitive development
Amount £234,035 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2010 
End 12/2010
 
Description Genetics, school environment and cognitive development
Amount £404,957 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Genome-wide association study - Wellcome Trust
Amount £55,727 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description GlaxoSmithKline -FMRI study comparing brain functional activation before and after 8 weeks of treatments with placebo
Amount £504,393 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description Glutamate and GABA in adults with autism; an in vivo study using magnetic resonance spectroscopy
Amount £354,175 (GBP)
Funding ID 091300 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Health risk trajectories across adolescence: Understanding gender differences
Amount £11,732 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description HeroGen - Genetics of Heroin Dependence (Asherson)
Amount £158,824 (GBP)
Funding ID 15/12/2726 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 10/2012 
End 09/2014
 
Description How does childhood maltreatment lead to depression in adults? A molecular study on inflammatory and metabolic pathways using the South East London Community Health (SELCoH) sample (Caspi Moffitt Danese CoPI)
Amount £50,000 (GBP)
Funding ID McGregor 97 
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start 06/2011 
End 05/2014
 
Description IMAGEN Integrated Project - Reinforcement-related behaviour in normal brain function and psychopathology.
Amount £356,770 (GBP)
Funding ID 37286 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description IMAGEN W.P7 - Reinforcement-related behaviour in normal brain function and psychopathology
Amount £174,070 (GBP)
Funding ID 37286 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description IMAGEN W.P8 - Reinforcement-related behaviour in normal brain function and psychopathology
Amount £195,412 (GBP)
Funding ID 37286 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description IN-VIVO MRS ASSAY OF BRAIN GLUTAMATE AND DRUG RESPONSE IN HUMANS AND A MOUSE MODEL OF AUTISM (Fernandes)
Amount £32,829 (GBP)
Funding ID 06/04/1922 
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start 12/2012 
End 11/2014
 
Description INTACT- Individually Tailored Stepped care for women with eating disorders
Amount £326,237 (GBP)
Funding ID 35988 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Identical twins discordant for autism: Epigenetic (DNA methylation) biomarkers of non-shared environmental influences
Amount £131,804 (GBP)
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Identification of novel biomarkers for disease progression in Alzheimer's disease (Newhouse)
Amount £131,273 (GBP)
Funding ID No4 
Organisation Johnson & Johnson 
Department Janssen-Cilag
Sector Private
Country Global
Start 10/2013 
End 09/2017
 
Description Identifuing generic and enviromental risk factors and their interplay for achivement at school-Award for Claire Haworth
Amount £175,368 (GBP)
Funding ID G0802681 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Identifying Genetic Predictors of Radiological Damage in Rheumatoid Arthritis ( Cathryn Lewis)
Amount £25,276 (GBP)
Funding ID SGL012\1019 
Organisation Academy of Medical Sciences (AMS) 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2015 
End 04/2016
 
Description Identifying patterns of genome-wide association in the development of cognitive, behavioural and psychiatric disorders
Amount £250,000 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Identifying the impact of mental disorder risk alleles on childhood neurodevelopment
Amount £1,415 (GBP)
Funding ID MR/M012964/1 Cardiff: 507568 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2015 
End 12/2016
 
Description Imitation in Autism
Amount £57,922 (GBP)
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Influence of genes & childhood experiences on the onset & outcome of Psychosis
Amount £48,900 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Information processing, IQ and social learning in ASD
Amount £4,810 (GBP)
Organisation King's College London 
Department Social Psychiatry
Sector Academic/University
Country United Kingdom
Start  
 
Description Initial organizational workshop to establish a consortium on the genetics of High Cognitive Abilities
Amount £4,074 (GBP)
Organisation The John Templeton Foundation 
Sector Academic/University
Country United States
Start 01/2007 
End 12/2007
 
Description Intellectual Development in Tuberous Sclerosis (Bolton)
Amount £63,162 (GBP)
Funding ID TRUST/RNA/AC/KW/36/4901 
Organisation Baily Thomas Charitable Fund 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2012 
End 03/2014
 
Description Interaction between genes and psychosocial factors in the aetiology and outcomes of psychotic disorders (Fisher)
Amount £76,090 (GBP)
Funding ID psychosis 1 
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start 04/2012 
End 03/2015
 
Description Interaction between genetic risk and chidhood adversity in the development of psychosis and depression
Amount £160,628 (GBP)
Funding ID G0802674 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description International Study of Genetic Factors in Exposure Treatments of Anxiety Disorders
Amount £301,248 (GBP)
Organisation Alexander von Humboldt Foundation 
Sector Public
Country Germany
Start  
 
Description International Study of Genetic Factors in Exposure Treatments of Anxiety Disorders (Eley)
Amount £301,248 (GBP)
Organisation Alexander von Humboldt Foundation 
Sector Public
Country Germany
Start 09/2011 
End 09/2015
 
Description International Travel Grant 2010
Amount £4,000 (GBP)
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Interoception and Autism Spectrum Disorders (Geoffrey Bird)
Amount £109,456 (GBP)
Funding ID TRUST/VC/AC/SG/3751/6536 
Organisation Baily Thomas Charitable Fund 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2016 
End 12/2017
 
Description Intervention within the British Autism Study of Infant Siblings (i-BASIS)
Amount £75,910 (GBP)
Funding ID 7267 
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Intervention within the British Autism Study of Infant Siblings (i-BASIS) - Bolton Booth
Amount £82,910 (GBP)
Funding ID #7267 
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2011 
End 03/2013
 
Description Investigating the phenotype and genetic architecture of myoclonic astatic epilepsy (Collier)
Amount £251,485 (GBP)
Funding ID MR/J011231/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2013 
End 12/2015
 
Description Investigation of Copy Number Variation as modifier loci in the co-morbidities and phenotype of Rolandic Epilepsy (Collier)
Amount £48,400 (GBP)
Funding ID 164/1547 
Organisation The Waterloo Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2012 
End 12/2013
 
Description Investigation of heritability and the genetic basis of subtypes of schizophrenia: a collaborative study
Amount £35,866 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description Investigation on contrast effects in children with autism
Amount £89,030 (GBP)
Funding ID ES/G035679/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Is childhood cruelty to animals a marker of child abuse in a population-based sample of twins
Amount £2,810 (GBP)
Organisation Royal Society for the Prevention of Cruelty to Animals 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2009 
End 12/2009
 
Description Is there a shared heritability for the type 2 diabetes and depression association? Fellowship (Rijsdijk, Lewis)
Amount £203,821 (GBP)
Organisation Novo Nordisk 
Department Novo Nordisk UK Research Foundation
Sector Charity/Non Profit
Country United Kingdom
Start 02/2014 
End 12/2017
 
Description KCL Primerdesign Student Sponsorship Stipend Top-Up for Georgia Powell-Smith
Amount £250 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description KConnect - Khresmoi Multilingual Medical Text Analysis, Search and Machine Translation Connected in a Thriving Data-Value Chain (Dr Richard Dobson)
Amount £256,500 (GBP)
Funding ID 644753 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 02/2015 
End 07/2017
 
Description Karen Ashwood Student Maintenance Grant
Amount £65,195 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Klaus J. Jacobs Research Prize: Best Practice Award (Caspi Moffitt)
Amount £344,045 (GBP)
Organisation Jacobs Foundation 
Sector Charity/Non Profit
Country Switzerland
Start 01/2011 
End 12/2015
 
Description Laboratory and clinical validation of a minimally-invasive assay to study the genomic fingerprint of stress (Danese Plomin)
Amount £81,689 (GBP)
Funding ID 1R21HL109396-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 08/2011 
End 07/2013
 
Description Laboratory and clinical validation of a minimally-invasive assay to study the genomic fingerprint of stress.
Amount £81,689 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Linking Adolescent cannabis exposure to schizophrenia: the role of DNA methylation
Amount £25,712 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description Linking Genetic Variation to Brain Anatomy and Behaviour in ASD-A follow on to the Autism Imaging Multicentre Project
Amount £37,500 (GBP)
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Longitudinal Epigenomic Analysis in Monozygotic Twins Discordant for Asthma (Jonathan Mill)
Amount £33,534 (GBP)
Funding ID 12-0072 Lead ref: 1333.018 
Organisation American Asthma Foundation 
Sector Charity/Non Profit
Country United States
Start 03/2015 
End 07/2015
 
Description Longtitudinal changes in DNA methylation: a study to investigate the dynamics of epigenetic discordance between genetically-identical twins (University of London (Central research funds)
Amount £5,300 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description MQ Fellows Award (Fisher) MQ Transforming Mental Health
Amount £225,000 (GBP)
Organisation MQ Transforming Mental Health 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2014 
 
Description MRC - Autism genetics and normal variation in cognition and behavior
Amount £110,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC - Contribution of genetics and early cognitive and emotional development to attention problems in middle childhood G0800054
Amount £201,974 (GBP)
Funding ID G0800054 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC - Cortical Morphometry in Autism Spectrum Disorder G0701370
Amount £273,108 (GBP)
Funding ID G0701370 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC - Developmental pathways into adolescent substance abuse: neurophysiologic, genetic and environmental determinants G0901858
Amount £977,753 (GBP)
Funding ID G0901858 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC - Developmental trajectories of psychosis in population-based samples: interplay between early adversity and familial risk - G1002366
Amount £275,864 (GBP)
Funding ID G1002366 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC - Low coverage sequencing for the detection and analysis of genomic structural variants in schizophrenia G1100583
Amount £1,015,920 (GBP)
Funding ID G1100583 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC - Next generation gene hunting in ALS G0900688
Amount £1,189,644 (GBP)
Funding ID G0900688 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC - Psychobiological sequelae of cumulative exposure to violence: The Environmental Risk Longitudinal Twin Study - G1002190
Amount £2,738,755 (GBP)
Funding ID G1002190 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC 09 SGDP DTA - Hannah Grayton
Amount £92,794 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description MRC 2009 SGDP Centre - Agnieszka Kepa
Amount £86,350 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description MRC 2009 SGDP Centre - Maciej Trazaskowoski
Amount £86,350 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description MRC 2009 SGDP Centre - Timothy Powell
Amount £86,350 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2010
 
Description MRC 2009 SGDP DTA - C Cheung
Amount £92,794 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description MRC 2009 SGDP Stats Gen - Jennifer Pararajasingham
Amount £63,640 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2012
 
Description MRC Centre Studentship for Caroline Skirrow
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC Centre Studentship for Chloe Wong
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC Centre Studentship for Corina Greven
Amount £65,273 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description MRC Centre Studentship for Helena Zavos
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC Centre Studentship for Jemma Day
Amount £86,907 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC Centre Studentship for Robert Keers
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC DTA Studentship for Hannah Wiltshire
Amount £86,907 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC DTA Studentship for Rachel Kember
Amount £86,907 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC G1002366 Developmental trajectories of psychosis in population-based samples: interplay between early adversity and familial risk (Fisher, Moffitt)
Amount £275,864 (GBP)
Funding ID G1002366 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2011 
End 09/2014
 
Description MRC New Investigator Award (Ronald)
Amount £450,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description MRC Social, Genetic and Developmental Psychiatry Centre (MRC Centenary Award) - (Fisher)
Amount £15,000 (GBP)
Funding ID G9817803-E02/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2012 
End 09/2013
 
Description MRC Social, Genetic and Developmental Psychiatry Centre. The Centenary Award (C Wong)
Amount £15,000 (GBP)
Funding ID G9817803-E02/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2012 
End 09/2015
 
Description MRC Social, Genetic and Developmental Psychiatry Centre. The Centenary Award (Haworth and Davis)
Amount £15,000 (GBP)
Funding ID G9817803-E02/1 
Organisation Medical Research Council (MRC) 
Department Medical Research Foundation
Sector Charity/Non Profit
Country United Kingdom
Start 10/2012 
End 08/2013
 
Description MRC studentship for Stephanie Lietz
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC studentship for Susanne Pfeifer
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2011
 
Description Maintenance of the NRXN1 knockout mouse colony (Fernandes)
Amount £25,000 (GBP)
Organisation Eli Lilly & Company Ltd 
Sector Private
Country United Kingdom
Start 01/2013 
End 01/2014
 
Description Mapping genetic - epigenetic interactions across the gerome (University of London (Central research funds))
Amount £3,500 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Medical Research Council-A population-based twin-study of autism spectrum disorders: genetic and environmental sources of cognitive and clinical heterogeneity G0500870
Amount £569,527 (GBP)
Funding ID G0500870 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Medical Research Council-Adolescent conduct problems: a biosocial model of risk G0500953
Amount £583,524 (GBP)
Funding ID G0500953 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Medical Research Council-Mental disorders from childhood to adulthood: The Dunedin Study age 38 followup G0601483
Amount £785,827 (GBP)
Funding ID G0601483 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Mental Disorders from childhood to adulthood
Amount £1,243,737 (GBP)
Funding ID G0601483 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Methylomic profiling in schizophrenia: Towards an integrated genetic-epigenetic approach (Schalkwyk)
Amount £112,451 (GBP)
Funding ID MR/K013807/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 06/2013 
End 05/2016
 
Description Mood instability in adult Attention Deficit/Hyperactivity Disorder
Amount £76,216 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Moodinflame - Early diagnosis, treatment and prevention of mood disorders targeting the activated inflammatory response system
Amount £386,803 (GBP)
Funding ID 222963 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Multi-level and trajectory modelling of environmental risk factors for childhood psychotic symptoms incorporating a new virtual systematic social observation technique (Helen Fisher)
Amount £388,885 (GBP)
Funding ID SQ140024 
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 11/2015 
End 05/2016
 
Description NIH Competing Research Application (R01 Maths)
Amount £1,134,051 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description NIH Competing Research Application (R21 Danese)
Amount £172,700 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description NIHR Biomedical Research Centre (BRC)-Functional characterisation of Ras-Grf2 gene variants in alcohol addiction and its treatment.
Amount £11,400 (GBP)
Organisation National Institute for Health Research 
Department NIHR Comprehensive Biomedical Research Centre, Guy's and St Thomas
Sector Public
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Analysis of neurotransmitter-induced transcriptional changes in human genotype-specific lymphoblastoid cell lines (pilot grant)
Amount £19,750 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-C-Reactive protein as a salivary marker of inflammation among children: a laboratory and clinical validation.
Amount £19,940 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Identification of genetic variations moderating alcohol consumption through sequencing of candidate genomic regions.
Amount £20,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Paternal age effects in autism: Exploring epigenetic mechanisms
Amount £20,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Transcriptomic analyses for treatment response to fentanyl in humans
Amount £9,977 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Transcriptomic profiles of inflammatory cytokines and receptors as biomarkers for major depressive disorder
Amount £17,584 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health Impact of mood instability and ADHD on adult behavioural disorders and psychopathology, NIHR/SLAM NHS Trust
Amount £76,216 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Programme grant
Amount £2,000,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description NIHR Senior Investigator Award 2011 - Bolton
Amount £60,000 (GBP)
Funding ID 2011 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2011 
End 03/2015
 
Description NIMH-The Psychiatric GWAS Consortium: Integrated and Coordinated GWAS Meta-Analyses
Amount £52,894 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description National Institute of Health Research (BRC)-Translational research: Mental disorders in young people
Amount £748,971 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description National Institutes of Health (R01 School Environment renewal)
Amount £822,000 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Neural correlates of empathy and perspective taking in adolescents with psychopathic traits and adolescents with autism spectrum disorder - Awarded to PhD student E O Nions (University of London (Central Research Funds))
Amount £5,340 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Neurobiological Correlates of Antidepressant Response After Treatment in Subjects with Major Depressive Disorder
Amount £14,002 (GBP)
Organisation Eli Lilly & Company Ltd 
Sector Private
Country United Kingdom
Start  
 
Description Newton001: Biomarkers of treatment naïve psychosis (Gerome Breen Simone De Jong)
Amount £43,147 (GBP)
Funding ID MR/M026337/1 
Organisation Medical Research Society 
Sector Learned Society
Country United Kingdom
Start 02/2015 
End 12/2015
 
Description Next Generation Gene Hunting in ALSA
Amount £100,000 (GBP)
Organisation Motor Neurone Disease Association (MND) 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Next generation gene hunting in ALS
Amount £87,346 (GBP)
Organisation ALS Association 
Sector Charity/Non Profit
Country United States
Start  
 
Description Novel Methods leading to New Medications in Depression and Schizophrenia (NEWMEDS)
Amount £2,347,840 (GBP)
Funding ID 115008 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description OPTIMISE Optimisation of Treatment and Management of Schizophrenia in Europe
Amount £1,421,520 (GBP)
Funding ID 242114 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Omega-3 Fatty Acids Supplementation for Adolescent Boys with Attention Deficit Hyperactivity Disorder A Double-blind, Randomized Controlled Trial/The Mother and Child Foundation
Amount £124,154 (GBP)
Organisation Mother and Child Foundation 
Sector Charity/Non Profit
Country India
Start  
 
Description Optimisation of sampling for CYP genotyping and analysis of CYP genotype as a predictor of steady state atomoxetine dose
Amount £10,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Origins of learning difficulties and behaviour problems: from behavioural genetics to behavioural genomics
Amount £1,868,807 (GBP)
Funding ID G0901245 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Origins of learning difficulties and behaviour problems: from behavioural genetics to behavioural genomics (Robert Plomin)
Amount £2,137,490 (GBP)
Funding ID MR/M021475/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2015 
End 09/2020
 
Description Pathways into persistent offending: the relative contribution of ADHD and substance misuse
Amount £271,233 (GBP)
Organisation Shire Pharmaceuticals 
Department Shire Development
Sector Private
Country United States
Start  
 
Description Pathways into persistent offending: the relative contribution of ADHD and substance misuse (Asherson CoPI)
Amount £271,233 (GBP)
Funding ID #8000054949 
Organisation Shire Pharmaceuticals 
Department Shire Development
Sector Private
Country United States
Start 06/2011 
End 05/2014
 
Description Persistent fatigue induced by interferon-alpha: a new immunological model for chronic fatigue syndrome (Dobson)
Amount £373,075 (GBP)
Funding ID MR/J002739/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 08/2012 
End 08/2015
 
Description Pharmacogenetic Pilot Study of Opioid Substitution Treatment
Amount £36,069 (GBP)
Organisation Reckitt Benckiser 
Sector Private
Country United Kingdom
Start  
 
Description Pharmacogenomic biomakers as a clinical decision making tools for clozapine treatment of schizophrenia. CRESTAR (RTD) - (Collier)
Amount £576,145 (GBP)
Funding ID 29/06/2664 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 11/2011 
End 10/2015
 
Description Pharmacogenomic biomarkers as clinical decision making tools for clozapine treatment of schizophrenia. CRESTAR (OTHER) (Collier)
Amount £85,802 (GBP)
Funding ID 279227 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 11/2011 
End 10/2015
 
Description Pharmacogenonmic biomarkers as clinical decision making tools for clozapine treatment of schizophrenia. CRESTAR (MNGT) (Collier)
Amount £11,361 (GBP)
Funding ID 29/06/2664 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 11/2011 
End 10/2015
 
Description Physiological and Cognitive Mediators of Gene x Environment Interaction Effects on Children`s Antisocial Behaviour
Amount £421,539 (GBP)
Funding ID ES/G020132/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Positive genetics: The nature and Nurture of Wellbeing in Adolescence
Amount £258,002 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start  
 
Description Positive genetics: The nature and Nurture of Wellbeing in Adolescence (Haworth)
Amount £260,025 (GBP)
Funding ID pf110044 
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 09/2011 
End 09/2014
 
Description Post Doctoral Fellowship for Kathryn Asbury
Amount £217,737 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start  
 
Description Prediction and analysis of regulatory SNP MAP of major depressive disorder - via the University of Aberdeen
Amount £337,054 (GBP)
Funding ID G0701003 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Prediction of prodromal schizophrenia using a triad of early risk factors in a longitudinal cohort of children (Fisher)
Amount £30,781 (GBP)
Funding ID Margaret Temple (2012) 
Organisation British Medical Association (BMA) 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2013 
End 03/2016
 
Description Preschool Autism Communication Trial (PACT)
Amount £12,706 (GBP)
Funding ID G0401546 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2010 
End 12/2010
 
Description Preterm birth as a risk factor for attention deficit hyperactivity disorder: a cognitive-neurophysiological sibling study (Kuntsi, Asherson, Rijsdijk)
Amount £169,944 (GBP)
Funding ID GN2080 
Organisation Action Medical Research 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2013 
End 03/2016
 
Description Production of a paper on aripiprazole and anti-psychotic weight-gain, and of a review on the use of aripiprazole in schizophrenia in both adults and adolescents/Bristol Myers Squibb
Amount £20,426 (GBP)
Organisation Bristol-Myers Squibb 
Sector Private
Country United States
Start 01/2007 
End 12/2007
 
Description Prof Patrick Bolton - MRC Centre studt - C. Tye
Amount £83,720 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Prof Robert Plomin - ESRC Stud - K. Hanscombe
Amount £83,720 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Provision of equipment and expertise/Sichuan University
Amount £10,946 (GBP)
Organisation Sichuan University 
Sector Academic/University
Country China
Start  
 
Description PsychDPC: Psychiatric diagnostic and prevention consortium (C Lewis)
Amount £132,291 (GBP)
Funding ID 15/08/2683 
Organisation European College of Neuropsychopharmacology (ECNP) 
Sector Charity/Non Profit
Country Netherlands
Start 01/2012 
End 12/2015
 
Description Psychiatric disorder and accelerated aging: The Dunedin Multidisciplinary Health and Development Longitudinal Cohort Study (Moffitt Caspi)
Amount £1,032,424 (GBP)
Funding ID MR/K00381X/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2013 
End 12/2016
 
Description Psychiatry Research Trust - DNA methylation and adolescent depression: an MZ differences study
Amount £47,800 (GBP)
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Psychiatry Research Trust - How does childhood maltreatment lead to depression in adults? A molecular study on inflammatory and metabolic pathways using the South East London Community Health (SELCoH) sample
Amount £50,000 (GBP)
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Psychosocial resilience in adolescent offspring of mothers with depression : testing causal mechanisms (Maughan via Cardiff)
Amount £5,006 (GBP)
Funding ID ES/J011657/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2013 
End 12/2014
 
Description Pyrosequencer for quantitative DNA methylation profiling in Alzheimer's Disorder
Amount £20,000 (GBP)
Funding ID ART-EG2010A-2 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2010 
End 12/2010
 
Description Quantitative review of risks for substance misuse
Amount £3,973 (GBP)
Organisation Academy of Medical Sciences (AMS) 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2006 
End 12/2006
 
Description ROAMER- A Roadmap for Mental Health Research in Europe (Schumann)
Amount £88,317 (GBP)
Funding ID HEALTH-F3-2011-282586 
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start 10/2011 
End 09/2014
 
Description Real-time functional magnetic resonance imaging (fMRI) Neurofeedback in children with ADHD (Attention Deficit Hyperactivity Disorder) (Rubia)
Amount £197,365 (GBP)
Funding ID 1890 
Organisation Action Medical Research 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2012 
End 02/2015
 
Description Replication of depression HiTDIP findings for selected genes in the depression case control sample collected at IOP-consultancy
Amount £56,160 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description Replication of proteome based plasma biomarkers identified by using the SomaLogic aptamer platform (Sattlecker)
Amount £9,000 (GBP)
Funding ID EPI Pilot Award 
Organisation King's College London 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 11/2012 
End 03/2013
 
Description Research grant Haruv Institute
Amount £43,849 (GBP)
Organisation Harbin Institute of Technology 
Sector Academic/University
Country China
Start 09/2016 
End 09/2017
 
Description Review of interventions for malteated children and adolescents (Fisher)
Amount £45,717 (GBP)
Funding ID RK 735943478 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 02/2013 
End 07/2014
 
Description Royal Society International Travel Grant
Amount £3,950 (GBP)
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Royal Society Rosalind Franklin Award 2011 - Raising primary-school children's awareness of women in SET through a new series of short picture books (Happe)
Amount £30,000 (GBP)
Funding ID RFA11/ER 
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2011 
End 07/2013
 
Description Russian Federation Grants for State support for research (Kovas)
Amount £3,100,000 (GBP)
Organisation Government of Russia 
Sector Public
Country Russian Federation
Start  
 
Description Schizophrenia and Advancing Paternal Age: Clinical and Molecular Characteristics
Amount £40,000 (GBP)
Organisation British Medical Association (BMA) 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Social Inequality and Children's Mental Health
Amount £209,414 (GBP)
Funding ID ES/H034897/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Social Motivation in Autism Spectrum Disorders (Coralie Chevallier)
Amount £78,360 (GBP)
Funding ID ES/G020523/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Social, psychological and genetic resilience to adversity in bipolar disorder
Amount £159,588 (GBP)
Funding ID ES/H04678X/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Socio-economic disparities in Alcohol and Drug Abuse in Adoloscents and Young adults
Amount £4,500 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description Socio-economic disparities in alcohol and drug use among adolescents and young adults
Amount £2,000 (GBP)
Organisation King's College London 
Department Social Psychiatry
Sector Academic/University
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description Specificity and familiability of EEG parameters in ADHD and ASD/Steel Charitable Trust
Amount £2,000 (GBP)
Organisation Steel Charitable Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Specificity and familiality of EEG parameters in ADHD and ASD
Amount £26,728 (GBP)
Organisation The Waterloo Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Start up funds to prepare a MRC research grant on the role of circadian rhythm genes on substance use disorders/Psychiatry Research Trust
Amount £20,440 (GBP)
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Studentship for Inti Pedroso, Biomedical Research Centre (BRC)
Amount £52,138 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description Suicidality: Treatment occurring in paediatrics (STOP)
Amount £71,498 (GBP)
Funding ID 261411 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Systematic Analysis of Cocaine Target Genes in Cocaine Addiction/Psychiatry Research Trust
Amount £23,000 (GBP)
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description TRiP: Translational Research in Psychiatry MC IRSES (Breen)
Amount £231,186 (GBP)
Funding ID FP7-PEOPLE-2011-IRSES 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 06/2012 
End 05/2016
 
Description TWIST: The Twins Wellbeing Intervention Study (Haworth)
Amount £9,900 (GBP)
Funding ID SG112183 
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 04/2012 
End 09/2013
 
Description Testing the efficacy of cannabidivarin (CBDV) treatment to reverse the deficits in social behaviour observed in the neurexin 1a (Nrxn1a) knockout mouse (Cathy Fernandes)
Amount £115,984 (GBP)
Organisation Great Western Research (GWR) 
Sector Academic/University
Country United Kingdom
Start 04/2016 
End 03/2017
 
Description The 'What is on Your Mind' app - developing a novel tool to improve outcomes for adolescents with depression and ADHD (Philip Asherson Jonna Kuntsi)
Amount £60,000 (GBP)
Funding ID GN2315 
Organisation Action Medical Research 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2015 
End 12/2016
 
Description The Biological mechanism of somatic symptoms in depression;The role of polyunsaturated fatty acids
Amount £37,531 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description The Colombo Twin and Singleton Study (CoTaSS) follow up
Amount £246,263 (GBP)
Funding ID 093206 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description The Genetics and Pharmacogenetics of Methamphetamine Abuse and Psychosis
Amount £27,219 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description The Psychiatric GWAS Consortium: Integrated & Coordinated GWAS Meta-Analyses 1/5
Amount £42,714 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description The adult consequences of being bullied in childhood. A 45-year prospective epidemiological study (Arseneault)
Amount £133,294 (GBP)
Funding ID MD120015 
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 12/2012 
End 12/2013
 
Description The cognitive requirements of cumulative culture: experiments with typically developing and autistic people ( Francesca Happe)
Amount £25,686 (GBP)
Funding ID ES/M006042/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 08/2015 
End 08/2018
 
Description The effect of intranasal oxytocin on social emotional functioning in anorexia nervosa (G Kalsi)
Amount £33,980 (GBP)
Organisation Swiss Anorexia Nervosa Foundation 
Sector Charity/Non Profit
Country Global
Start 01/2013 
End 10/2013
 
Description The genetics of High Cognitive Abilities
Amount £132,463 (GBP)
Organisation The John Templeton Foundation 
Sector Academic/University
Country United States
Start  
 
Description The long-term consequences of infant domestic adoption (Barbara Maughan)
Amount £88,232 (GBP)
Funding ID KID/41956 
Organisation Nuffield Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2015 
End 09/2016
 
Description The relationship between imitation and social skills and disabilities
Amount £82,329 (GBP)
Funding ID ES/F034601/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description The relationship of Essential Fatty Acids to cognitive, electrophysiological and behavioural function in adults with attention deficit hyperactivity disorder and controls
Amount £101,149 (GBP)
Organisation Galencia 
Department Vifor Pharma UK
Sector Private
Country United Kingdom
Start  
 
Description The relationship of Essential Fatty Acids to cognitive, electrophysiological and behavioural function in adults with attention deficit hyperactivity disorder and controls - Asherson
Amount £101,148 (GBP)
Organisation Galencia 
Department Vifor Pharma UK
Sector Private
Country United Kingdom
Start 10/2011 
End 09/2015
 
Description The role of antisocial friends in the development of antisocial behaviour during adolescence (Eley - Fellowship)
Amount £85,328 (GBP)
Funding ID ES/I036524/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 06/2011 
End 05/2014
 
Description The role of antisocial friends in the development of antisocial behaviour during adolescence.
Amount £85,328 (GBP)
Funding ID ES/I036524/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description The role of epigenetic processes in mediating the molecular and behavioural responses to stress in the dentate gyrus`
Amount £66,291 (GBP)
Funding ID BB/G02507X/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start  
 
Description Trans-Generational Study of the Effects of Sex and Development Stage on the Behaviour of the Offspring of Aged Fathers (Cathy Fernandes)
Amount £4,171 (GBP)
Funding ID 0285-3965-4609 
Organisation Icahn School of Medicine at Mount Sinai 
Sector Academic/University
Country United States
Start 06/2015 
End 05/2016
 
Description Transgenerational effects of advanced paternal age on offspring (Fernandes)
Amount £18,247 (GBP)
Funding ID 0285-3965-4609 
Organisation Icahn School of Medicine at Mount Sinai 
Sector Academic/University
Country United States
Start 06/2013 
End 05/2014
 
Description Transition to Young Adulthood in Autism Spectrum Disorder: Mental Health and Wellbeing in a Population-Based Sample of Twins (Happe Colvert)
Amount £59,629 (GBP)
Funding ID TRUST/RNA/AC/KW/2415/4904 
Organisation Baily Thomas Charitable Fund 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2013 
End 05/2015
 
Description Translating gene-environment interaction from aetiology to personalised medicine for anxiety and depression - Fellowship (Keers)
Amount £270,776 (GBP)
Funding ID MR/K021281/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 07/2013 
End 07/2016
 
Description US NIMH-Molecular epigenetic studies of major depression US NIMH
Amount £32,171 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description US National Institute of Child Health and Human Development- Genetics of general and specific mathematics disabilities
Amount £387,075 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2009 
End 12/2009
 
Description US National Institute of Child Health and Human Development-Reading disability QTLs: Pooled DNA on microarrays
Amount £539,533 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Understanding and influencing pupils' choices as they prepare to leave school (Plomin)
Amount £117,942 (GBP)
Funding ID EDU/40881 
Organisation Nuffield Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2012 
End 09/2014
 
Description Understanding how genomic, transcriptomic and proteomic variation is associated with metabolic changes in Alzheimer's Disease (Dobson)
Amount £199,777 (GBP)
Funding ID 15/06/1900 
Organisation Alzheimer’s Society 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2012 
End 09/2015
 
Description Understanding the neuroendocrine regulation of weight gain psychosis
Amount £32,336 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description Understanding the role of stress in the cognitive abnormalities of psychosis
Amount £78,573 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start  
 
Description Unifying genetic and epigenetic approach to psychiatric disorders in children and adolescents : Analysis of the human brain. ( Gunter Schumann)
Amount £38,000 (GBP)
Funding ID 259-2012-23 
Organisation Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS) 
Sector Private
Country Sweden
Start 01/2015 
End 12/2015
 
Description Unifying genetic and epigenetic approach to psychiatric disorders in children and adolescents : Analysis of the human brain. (Schumann)
Amount £50,667 (GBP)
Funding ID 259-2012-23 
Organisation Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS) 
Sector Private
Country Sweden
Start 09/2012 
End 12/2013
 
Description University of London (Central Research Funds) Can cerebral blood flow predict response to treatment in first episode psychosis?
Amount £6,615 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Vacation Scholarship of Francesca Silman
Amount £1,480 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description Validation of the classical CUMS (Chronic Unpredictable Mild Stress) model - Behavioural Validation (Fernandes)
Amount £218,718 (GBP)
Organisation Johnson & Johnson 
Department Janssen-Cilag
Sector Private
Country Global
Start 01/2013 
End 12/2016
 
Description Validation of the classical CUMS (Chronic Unpredictable Mild Stress) model - Molecular Validation Studentship (Fernandes)
Amount £142,473 (GBP)
Funding ID No.2 
Organisation Johnson & Johnson 
Department Janssen-Cilag
Sector Private
Country Global
Start 01/2014 
End 12/2017
 
Description W.P7-IMAGEN Integrated Project Reinforcement-related behaviour in normal brain function and psychopathology
Amount £268,371 (GBP)
Funding ID 37286 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Wellcome Trust VIP Award-Integrating Molecular and Bioinformatic Genetic Studies in stimulant Abuse
Amount £50,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description Whole genome analysis of copy number variation in a large case control study of recurrent depression
Amount £215,062 (GBP)
Funding ID 236858 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Whole genome and exome sequencing of families with bipolar disorder and depression Fellowship (Alsabban, Breen)
Amount £182,807 (GBP)
Organisation Government of Saudi Arabia 
Sector Public
Country Saudi Arabia
Start 12/2012 
End 12/2014
 
Description Why do children who are bullied manifest early-onset mental health problems? A genetic and experimental investigation
Amount £132,670 (GBP)
Organisation Jacobs Foundation 
Sector Charity/Non Profit
Country Switzerland
Start  
 
Description Work Package WP8 of NEWMEDS, European Commision Innovative Medicines Initiative
Amount £677,360 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Title HIGH PERFORMANCE COMPUTING (HPC) CLUSTER at the MRC SGDP Centre for BioInformatics 
Description Bioinformatics involves making sense of high-dimensional biological data (e.g., genomic, transcriptomic, and proteomic information) and is thus critical for the Centre's long-term strategy of understanding pathways between genes and behaviour. Although several Centre members are highly knowledgeable about bioinformatics, the goal of the bioinformatics resource and the High Performance Computing Cluster is to provide expertise for the Centre community. The resource is led by Dr Leo Schalkwyk and is supported by two Centre-funded posts, one for bioinformatics (Dr Matthew Davies who was employed in September 2008) and one for programming and co-ordinating the Centre's Linux cluster which currently links 31 compute nodes and provides 64 AMD Opteron 64-bit CPUs with 82 Gb RAM (Mr Stuart Newman). Bioinformatics applications serve two main functions: data integration and data analysis. The cluster is vital to provide both capacity and speed: capacity to store, integrate and distribute large databases, and speed to perform compute-intensive calculations. The cluster is crucial not only for bioinformatics analyses but also for statistical genetics such as analyses of microarray data, meta-analyses and quantitative genetic maximum-likelihood structural equation analyses. Other key issues that are addressed by the team include bioinformatics approaches to the analysis of genome-wide association studies (GWAS) both by pooling and individual genotyping, the use of machine-learning techniques for data integration in interpreting GWAS results, and studies of correlational structure of gene expression profiles across tissues using mouse reference populations. Three Centre PhD students are also helping to grow this resource 
Type Of Material Improvements to research infrastructure 
Year Produced 2007 
Provided To Others? Yes  
Impact In addition to its support role, two examples of major substantive research programmes for the bioinformatics team are to compare gene expression profiles in brain and blood and to assess gene expression profiles as they respond to environmental changes including responses to drugs. 
 
Title MRC SGDP Centre Labs Management Systems 
Description Bernard Freeman has continued to develop a range of software systems that could have potential for technology transfer. All the systems have improved to the point where there could be interest from commercial laboratories. The barcode tracking system for managing samples has expanded tremendously during the last five years to allow more functionality, flexibility and ease of use and is currently undergoing a significant redevelopment to turn it into a commercially attractive package. The software link between the tracking system and our robotics platforms has also expanded to now allow the incorporation of a hotel storage system allowing very large numbers of samples to be handled by the system without user intervention. The SGDP Laboratories have taken the first steps toward gaining accreditation status which will further allow them to carry out specialized commercial genotyping services such as zygosity testing and specific tests (such as for drug metabolising status). The laboratories are also in the process of developing a series videos that will be available as an online training resource. 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact These developments will eventually cover all aspects of laboratory work carried out at the Centre and we are hoping for this to not only be a useful resource for the Centre but also of potential commercial value. The processes and procedures developed have helped in the development of other labs across Kings College London and at other Higher Education Facilities 
 
Title New tools for pathway analysis of genetic data and CNS pathway 
Description Dr Gerome Breen is collaborating on several commercial projects. One is with GeneGo and J&J to devlop new tools for pathway analysis of genetic data and CNS pathway. This is three year project and will result in IOP having first access and use of annotation and tools developed and a perpetual license to Metacore's advanced software and tools. 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact IOP having first access and use of annotation and tools developed and a perpetual license to Metacore's advanced software and tools. Dr Breen is also coinvestigator on the MRC-GSK funded Genome-Wide Aassociation Study for Major Depression and genetics coordinator for the NIHR Biomedical Research Centre for Mental Health, the lab core of which is in the SGDP Centre Labs 
 
Description - Emerald Logic, (US SME), Patrick Lilley (R Dobson) 
Organisation Emerald Logic
Country United States 
Sector Private 
PI Contribution Dr Richard Dobson's BRC Bioinformatics research team based at the SGDP Centre provides the sharing of datasets
Collaborator Contribution Patrick Lilley at Emerald Logic, (US SME) contributes analysis methods
Impact Our collaborator is also on multiple grant applications of Dr Richard Dobson's team
Start Year 2012
 
Description A MRI study on a sub sample of the Gendep Human Pharmacogenetics study 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution The study was initiated with funding from GSK to attempt to relate phenotypic characteristics, candidate genotypes and structural and functional MRI brain scans in depressed subjects.
Impact The study has been continued as part of the NIHR Biomedical Research Centre ( BRC) biomedical technologies theme. Fifty subjects who were part of the GENDEP or DeCC studies have so far been scanned. Preliminary analyses of hippocampal volume and shape in relation to 5HTTLPR and DBNF genotypes are currently underway. The study is an example of Centre projects that integrate brain imaging and genomics.
Start Year 2007
 
Description A genome scan for quantitive loci for early hyperactivity 
Organisation Nuffield Foundation
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution A collaboration to examine the genome scan in order to identify the loci for early detection of hyperactivity
Impact publications. See above section
 
Description A genome scan for quantitive loci for early hyperactivity 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution A collaboration to examine the genome scan in order to identify the loci for early detection of hyperactivity
Impact publications. See above section
 
Description A longitudinal follow up study of autism spectrum disorders 
Organisation Nuffield Foundation
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution This study follows a group of high functioning individuals with autism into middle adult life in order to determine how these individuals are managing at this point in their lives. In addition, their siblings are being assessed in order to determine how individuals with the broader autism phenotype adjust and function in adult life and whether or not their offspring are at any increased risk for autism spectrum disorders.
Impact The project will further our understanding of the ontogeny of autism spectrum disorder and the broader autism phenotype into adult life and the architecture of the familial liability to autism. The work is based on follow up of samples that were originally studied by MRC-funded research.
Start Year 2007
 
Description A quantitative and molecular genetic study of psychological processes as mediators of genetic effects on hyperactivity 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution The main aim of this project was to use a twin design to identify cognitive-energetic processes that mediate genetic influences on attention deficit hyperactivity disorder (ADHD) symptoms in a general population sample. We completed individual 2.5-hour assessments, carried out in testing rooms at the Centre, on 672 twin pairs (1,344 children). In initial analyses we (1) established test-retest reliability for the cognitive variables, (2) demonstrated a moderate degree of genetic influences for several measures of reaction time (RT), inhibition and working memory performance, and (3) investigated methodological issues, showing for example how psychometric properties (reliability, ceiling effects) of the measures influenced the heritability estimates and how by creating composite measures we could increase reliability and heritability. Key phenotypic analyses indicated an association between ADHD symptom scores and, in particular, high RT variability (RTV), slow mean RT, poor inhibition and choice impulsivity. Further, we showed how some aspects of cognitive performance in ADHD can be modulated by motivational or energetic factors: for example, RTV normalised in a high-ADHD symptoms group in a condition with a faster presentation rate of stimuli and rewards. For choice impulsivity and delay aversion, we showed associations that were gender-specific and specific to inattentiveness rather than hyperactivity-impulsivity. Multivariate model fitting analyses indicated both shared and unique etiological pathways. For example, the shared genetic influences on ADHD symptom scores and RTV were largely also shared with those on MRT, whereas these were largely independent of the genetic influences ADHD symptom scores share with IQ. Molecular genetic analyses indicated, for example, an association between hyperactivity-impulsivity and the dopamine transporter, and between inattentiveness and the dopamine D4 receptor genes. Our further analyses suggested that, in middle childhood, symptoms of hyperactivity-impulsivity and oppositional behaviour may represent the same underlying liability, whereas the inattentive domain is more distinct. We additionally measured activity level mechanically with actigraphs and identified a common underlying activity level factor, based on both actigraph and behavioural ratings data, which was highly heritable (92%).
Impact The project forwarded the Centre's aims by refining the cognitive endophenotype for ADHD using a general population sample, refining theory and refining the association between the two ADHD symptom domains. The focus on a continuous dimension of ADHD symptoms matches the Centre's aims and complements our other research on ADHD, where we have focused on clinical diagnoses. This project was made possible by the collaborative interdisciplinary opportunities at the Centre. First, given the combined expertise of Kuntsi, Asherson and Rijsdijk, we were able to incorporate cognitive, quantitative genetic and molecular genetic strategies. Second, the recruitment of the sample from the larger 'TEDS' cohort was made possible by collaboration with Plomin. The project has contributed to the training of students on the Centre 1+3 PhD programme, as students supervised by Kuntsi, Asherson and Rijsdijk have been able to analyse data from the project.
 
Description A study of Genetics of Mathematical Cognition and Disabilities (Plomin) 
Organisation Goldsmiths, University of London
Department Department of Psychology
Country United Kingdom 
Sector Academic/University 
PI Contribution Co-investigators on an NIH grant that was renewed in 2008 to conduct in-home testing of domain-general and maths-specific cognitive skills underpinning psychometric maths ability and disability for 500 TEDS families with children selected for domain-general (low maths + low reading) and maths-specific (low maths + normal reading) problems, which will provide interesting comparisons with the web-based data that we plan to collect as part of our MRC programme grant research at age 16.
Collaborator Contribution Collaborator is principal investigator on this grant.Analysis and assistance in writing papers based on the quantitative data.
Impact Although no publications have yet been forthcoming from the renewal funded in 2008, the previous grant was responsible for several collaborative publications: 'Scant evidence for Spearman?EUR(TM)s law of diminishing returns in middle childhood'; PMID18360741; PMID19634033; PMID19732386; PMID17983460; PMID19470122; 'The ABCs of math: A genetic analysis of mathematics and its links with reading ability and general cognitive ability'; 'A twin study into the genetic and environmental influences on academ
 
Description A study of Genetics of Mathematical Cognition and Disabilities (Plomin) 
Organisation Ohio State University
Country United States 
Sector Academic/University 
PI Contribution Co-investigators on an NIH grant that was renewed in 2008 to conduct in-home testing of domain-general and maths-specific cognitive skills underpinning psychometric maths ability and disability for 500 TEDS families with children selected for domain-general (low maths + low reading) and maths-specific (low maths + normal reading) problems, which will provide interesting comparisons with the web-based data that we plan to collect as part of our MRC programme grant research at age 16.
Collaborator Contribution Collaborator is principal investigator on this grant.Analysis and assistance in writing papers based on the quantitative data.
Impact Although no publications have yet been forthcoming from the renewal funded in 2008, the previous grant was responsible for several collaborative publications: 'Scant evidence for Spearman?EUR(TM)s law of diminishing returns in middle childhood'; PMID18360741; PMID19634033; PMID19732386; PMID17983460; PMID19470122; 'The ABCs of math: A genetic analysis of mathematics and its links with reading ability and general cognitive ability'; 'A twin study into the genetic and environmental influences on academ
 
Description A three-year case control study to identify genes associated with susceptibility to bipolar depression (BaCCs) 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution This is a case-control collection 500 cases of bipolar disorder of white European ethnic origin and 500 ethnically matched healthy, screen controls. The DNA of the cases contributed to the Wellcome trust Case control Consortium (final total of 2000 cases) and the core phenotyping methodology used throughout the Wellcome Trust Case Control Consortium study was the one devised by Farmer and McGuffin (the OPCRIT system).
Impact In addition to the landmark June 2007 "seven common disorders" Nature paper many other high profile publications have resulted. We have also published several candidate-gene association study papers based on this collection. The series, one of the largest intensely phenotyped studies of bipolar disorder, has also allowed a number of interesting add-on studies looking at environmental stressors in collaboration with Sahakian's group at Cambridge.
 
Description ACTION 
Organisation Diagenode
Country Belgium 
Sector Private 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual diffe