MRC Social, Genetic and Developmental Psychiatry Centre

Lead Research Organisation: King's College London
Department Name: Social Genetic and Dev Psychiatry Centre

Abstract

Nearly all psychiatric disorders are influenced by both genes and environment, often in equal measure, and most adult psychiatric disorders originate in childhood. For these reasons, the MRC Social, Genetic and Developmental Psychiatry (SGDP) Centre was launched in 1994 as the first of the MRC?s large interdisciplinary research centres in order to bring together social (environmental) and genetic strategies to understand the development of mental health and illness. The MRC SGDP Centre continues to be the only centre of excellence nationally or internationally with this interdisciplinary theme. The focus of the MRC SGDP Centre is on common psychiatric disorders that have a huge impact on people?s everyday lives such as mood disorders (anxiety and depression), ?externalising? disorders (disruptive behaviour including hyperactivity and addictions), and cognitive disorders (learning disabilities and the autistic spectrum). The Centre?s mission includes research, translation and training.

To achieve its research mission, the Centre has successfully recruited a broad range of 28 experts from psychiatry, psychology, neuroscience, molecular genetics, and quantitative and statistical genetics and facilitated their working together in the Centre?s new #16-million building. The hallmark of the MRC SGDP Centre is collaborative interdisciplinary research, which has produced pioneering findings at the developmental interface between genes and environment with far-reaching implications for diagnosis, treatment and prevention of mental illness. In order to add to the synergy created by its SGDP themes and existing resources, the Centre?s major new research request for 2010-15 is to develop three new resource areas ? bioinformatics, epigenetics and electrophysiology.

The second aspect of the Centre?s mission is to translate its research findings to clinical practice and public health policy. Translation of the Centre?s research is facilitated by its status as a department of the Institute of Psychiatry, which is a world-class psychiatric research institution and is in partnership with the Maudsley Hospital and the South London and Maudsley NHS Foundation Trust, the premier NHS mental health trust.

In terms of its training mission, the Centre?s 4-year PhD programme - launched in 1997, the first of its kind in the UK - continues to thrive, with nine new students accepted each year all of whom are supported with studentships. The Centre makes its expertise available more widely through its annual one-week Summer School for 70-100 researchers and doctors from around the world. A goal of the Centre during 2010-2015 is to greatly extend its educational reach through the development of e-learning programmes.

Technical Summary

Founded in 1994, the MRC Social, Genetic and Developmental Psychiatry (SGDP) Centre?s overarching theme is to bring together social (environmental) and genetic strategies to study the development of mental health and illness. Its focus is on common psychiatric disorders that emerge in childhood such as mood disorders (anxiety and depression), ?externalising? disorders (disruptive behaviour including hyperactivity and addictions), and cognitive disorders (learning disabilities and the autistic spectrum). The MRC SGDP Centre now includes 28 researchers with permanent appointments whose offices, students and research teams are in the MRC SGDP building. During 2005-09, the Institute of Psychiatry (IoP) has invested heavily in the Centre, with continuing commitments that will cost #10m during 2010-15. In addition, the IoP has committed an additional #2m in new money during 2010-15 if the Centre is renewed.

The Centre?s mission includes research, translation and training. Its progress in research at the developmental intersection between genes and environment has been outstanding as assessed in terms of collaboration, impact of publications and grants. A key feature of the Centre?s progress during the current grant period has been the appointment of seven new researchers who will increase the Centre?s strength at multiple levels of analysis between genes and behaviour. In order to add to the synergy created by its SGDP themes and existing resources in molecular and statistical genetics, the Centre?s major new research request for 2010-15 is to develop three new resource areas ? bioinformatics, epigenetics and electrophysiology ? with diminishing support over the five years as these resource areas become self-supporting by contributing to new research grants.

Translating research findings into knowledge useful for improving health is a strength of the Centre because the Centre is embedded within IoP with its unrivalled strengths in psychiatric research and with its strong links with South London and Maudsley NHS Foundation Trust which is the premier mental health trust in the UK. In terms of training, the Centre?s 1+3 MSc/PhD programme has doubled in size during the current grant period to nine students per year all of whom are fully supported with studentships. For 2010-15, support is requested for four studentships which is half of the Centre?s total budget request. The Centre makes its expertise available more widely through its self-supporting annual one-week Summer School for 70-100 researchers. The present proposal requests support to extend our educational research throughout the world by the development of e-learning programmes.

Organisations

Publications

10 25 50
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Booth RDL (2018) Evidence of Reduced Global Processing in Autism Spectrum Disorder. in Journal of autism and developmental disorders

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Brewer R (2016) Can Neurotypical Individuals Read Autistic Facial Expressions? Atypical Production of Emotional Facial Expressions in Autism Spectrum Disorders. in Autism research : official journal of the International Society for Autism Research

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Brunsdon VE (2014) Exploring the 'fractionation' of autism at the cognitive level. in Autism : the international journal of research and practice

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Carter Leno V (2015) Callous-unemotional traits in adolescents with autism spectrum disorder. in The British journal of psychiatry : the journal of mental science

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Elmose M (2014) Being aware of own performance: how accurately do children with autism spectrum disorder judge own memory performance? in Autism research : official journal of the International Society for Autism Research

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Euesden J (2015) The relationship between schizophrenia and rheumatoid arthritis revisited: genetic and epidemiological analyses. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

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Euesden J (2015) PRSice: Polygenic Risk Score software. in Bioinformatics (Oxford, England)

 
Description A Bayesian network model of gene expression,genotype and phenotype in the psychosis of Alzheimer's disease
Amount £144,516 (GBP)
Funding ID ART-RF2007-3 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description A Genome association study of Unipolar depression and Initial exploration of functional Allelic Variation
Amount £1,168,363 (GBP)
Funding ID G0701420 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description A MRI study on a sub-sample of the GENDEP human Pharmacogenomics study
Amount £102,558 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description A blood test for Alzheimer's disease (Computational approaches to identify Alzheimer's disease progression biomarkers and evaluate their performance)
Amount £49,500 (GBP)
Organisation Rosetrees Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description A double-blind, placebo-controlled study of neural correlates of depression following antidepressant treatment
Amount £800 (GBP)
Organisation The Royal Society 
Sector Academic/University
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description A feasibility study of different device parameters for the management of patients with treatment resistant major depressive disorder, single or recurrent episode, with deep brain stimulation (McGuffin, Farmer, Abdelghani)
Amount £70,680 (GBP)
Funding ID NM-09-035-EU-DB 
Organisation St. Jude Medical 
Sector Private
Country United States
Start 09/2011 
End 08/2013
 
Description A genome wide association study of the relationship between body mass index (BMI), type II diabetes and recurrent depression" EU Marie Curie Fellowship for Dr Margarita Rivera Sanchez
Amount £126,718 (GBP)
Funding ID 236858 
Organisation Marie Sklodowska-Curie Actions 
Sector Academic/University
Country Global
Start  
 
Description A genome wide association study of unipolar depression
Amount £1,178,240 (GBP)
Funding ID G0701420 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2008 
End 01/2010
 
Description A genome-wide scan for novel imprinted loci
Amount £14,986 (GBP)
Organisation The Royal Society 
Sector Academic/University
Country United Kingdom
Start  
 
Description A multi-faceted approach to identifying epigenomic dyfusion in Alzheimer's disorder and associated neuropsychiatric co-morbidities: discovering epigenetic biomarkers in brain tissue and peripheral blood
Amount £545,266 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description A multi-faceted approach to identifying epigenomic dyfusion in Alzheimer's disorder and associated neuropsychiatric co-morbidities: discovering epigenetic biomarkers in brain tissue and peripheral blood
Amount £278,838 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description A multi-site study of the genetics of child anxiety and predictors of treatment response
Amount £497,564 (GBP)
Funding ID G0901874 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description ADAMS Genomic variations underlying common neuropsychiatric diseases and disease-related cognitive traits in different human populations (3m euros across 12 participants)
Amount £191,070 (GBP)
Funding ID 242257 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description ADHD, an unmet need: increasing the recognition of behavioural problems associated with ADHD within St Andrews Healthcare
Amount £61,521 (GBP)
Organisation St. Andrew's Healthcare 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Adult outcomes and needs among high functioning individuals with autism spectrum disorders and their siblings
Amount £183,900 (GBP)
Organisation Nuffield Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Alicia Koplowitz Foundation Fellowship - E Taylor
Amount £118,005 (GBP)
Organisation Alicia Koplowitz Foundation 
Sector Charity/Non Profit
Country Spain
Start  
 
Description Alicia Koplowitz Foundation Fellowship - Taylor & Simonoff
Amount £124,669 (GBP)
Organisation Alicia Koplowitz Foundation 
Sector Charity/Non Profit
Country Spain
Start  
 
Description An fMRI Pilot study if the effects of cognitive behavioural therapy in bulimia nervosa: a strategy for translational research, SLAM NHS Trust
Amount £18,840 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description An imaging genomic investigation of major depressive disorder (MDD)
Amount £22,150 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description An investigation into Blood sampling of EFAs, Behavioural Questionnaries and Assessments of Brain Function in ADHD Participants and Healthy Matched Controls
Amount £15,450 (GBP)
Organisation Vion Pharmaceuticals 
Sector Private
Country United States
Start  
 
Description An investigation of replicated genetic associations from a genome - wide study of sporadic MNP
Amount £350,000 (GBP)
Funding ID G0600974 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Analytic infrastructure for the neuroimaging centre (South London and Maudsley NHS Foundation Trust)
Amount £39,509 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Antenatal depression and the epigenetics of developmental programming (Mill)
Amount £18,498 (GBP)
Funding ID 21/01/1953 
Organisation Brain & Behaviour Research Foundation 
Sector Charity/Non Profit
Country United States
Start 01/2013 
End 01/2015
 
Description Application of conformal predictors to functional magnetic resonance imaging
Amount £14,393 (GBP)
Funding ID G0802594 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Attentional Bias Modification: Development and testing of a school-based Cognitive Vaccine for the reduction and prevention of child anxiety (Eley - Lester)
Amount £240,869 (GBP)
Funding ID MR/J011762/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 08/2012 
End 07/2014
 
Description Autism Phenotypes in Tuberous Sclerosis: Risk Factors, Features & Architecture (Bolton)
Amount £82,714 (GBP)
Funding ID #7696 
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start 06/2012 
End 05/2015
 
Description Autism Spectrum and Attention Deficit Hyperactivity Disorders in Tuberous Sclerosis: Risk Factors, Features & Architecture (Bolton)
Amount £80,000 (GBP)
Funding ID 02/02/1955 
Organisation Tuberous Sclerosis Association 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2012 
End 08/2014
 
Description Autism genetics and normal variation in cognition and behavior
Amount £110,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Autism-spectrum disorders : treating co-morbid social anxiety disorder with adapted cognitive behaviour therapy Fellowship D Spain (Happe)
Amount £273,370 (GBP)
Funding ID CDRF-2012-03-059 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 06/2013 
End 05/2016
 
Description BRC - A new screening tool for the prediction of psychiatric adverse effects in patients receiving interferon-a treatment for chronic viral hepatitis C
Amount £75,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC - Genetic causes of Neurodevelopmental Delay in Children: translation and interpretation of novel pathogenic copy number variants and novel rare exonic mutations into clinical genetic practice
Amount £47,569 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC - Investigating Adverse Effects of Psychiatric Drugs through Data-Mining of Electronic Health Records and Integration of Clinical and Genomic Data (Dobson)
Amount £53,929 (GBP)
Organisation Guy’s & St Thomas’ Charity 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2013 
End 03/2014
 
Description BRC A study of blood-based markers of brain amyloid burden in monozygotic twins discordant for cognitive impairment (Kiddle)
Amount £40,000 (GBP)
Funding ID BRC EMCT Pilot Funding 
Organisation King's College London 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 11/2012 
End 03/2013
 
Description BRC Depression manager software
Amount £20,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC Gene expression profiling in the MRC Brain bank : a systems based biology approach to Dementia (Newhouse)
Amount £28,000 (GBP)
Funding ID BRC EMCT Pilot Funding 
Organisation King's College London 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 11/2012 
End 03/2013
 
Description BRC Project - Substance Use Disorders
Amount £747,834 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC Project - Substance Use Disorders
Amount £962,588 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC Pump Priming - An integrated framework to analyze genetic data of complex disorders
Amount £20,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC Theme: Biomedical Technologies
Amount £2,186,695 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC funding to extract parental DNA samples - Dr Eley
Amount £36,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description BRC studentship for Charlotte Nymberg
Amount £48,120 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 10/2009 
End 09/2012
 
Description Baily Thomas Charitable Fund Project Grants
Amount £59,629 (GBP)
Organisation Baily Thomas Charitable Fund 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2012 
End 06/2014
 
Description Biomedical Research Centre for Mental Health - EMCT Cluster - BioResource for Mental Health (Breen)
Amount £2,432,434 (GBP)
Funding ID SLAM NHS Trust EMCT Cluster 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2012 
End 03/2017
 
Description Biomedical Research Centre for Mental Health - EMCT Cluster - Biomarkers and genomics (Breen, Asherson, McGuffin)
Amount £1,402,802 (GBP)
Funding ID EMCT Cluster SLAM NHS Trust 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2012 
End 03/2017
 
Description Brain correlates of Childhood Maltreatment
Amount £396,082 (GBP)
Organisation Kids company 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description British Academy Postdoctoral Fellowship (Haworth)
Amount £258,002 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start  
 
Description Building CNS focised Connectivity Maps of CNS drugs - Pilot Study
Amount £20,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Childhood trauma, inflammation and depression: a test of the biological embedding hypothesis
Amount £20,345 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start 01/2010 
End 12/2010
 
Description Cognitive-Neurophysiological markers in ADHD: a follow-up study of ADHD and control sibling pairs.
Amount £194,528 (GBP)
Funding ID 1777 
Organisation Action Medical Research 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Collection of control subjects for genetic studies from Ethiopia/Virginia Commonwealth University
Amount £10,000 (GBP)
Organisation Virginia Commonwealth University 
Sector Academic/University
Country United States
Start  
 
Description Combinatorial biomarkers for dementia prodromes, prediction, pathology and progression
Amount £715,000 (GBP)
Funding ID ART-PG2010-4 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Comparative analysis of primate genomes, transcriptomes and proteomes with an emphasis on cognitive capabilities
Amount £317,277 (GBP)
Funding ID 28594 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Contract with RGA UK Services
Amount £123,000 (GBP)
Organisation RGA UK Services Ltd 
Sector Private
Country United Kingdom
Start 10/2016 
End 09/2017
 
Description Contribution of genetics and early cognitive and emotional development to attention problems in middle childhood (Fellowship for Karla Holmboe)
Amount £193,914 (GBP)
Funding ID G0800054 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Copy number variations conferring risk of psychiatric disorders in children
Amount £428,526 (GBP)
Funding ID 223423 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Creating an early diagnostic test for Alzheimer's - transforming our ability to tackle the disease (Dobson)
Amount £79,457 (GBP)
Funding ID 171 
Organisation Alzheimer’s Society 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2013 
End 03/2016
 
Description DNA methylation and adolescent depression: an MZ differences study (Eley Dempster Mill)
Amount £47,800 (GBP)
Funding ID McGregor 97 
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start 09/2011 
End 08/2013
 
Description DTA Professor Anne Farmer
Amount £82,530 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2006 
End 09/2010
 
Description Defining the role of micro RNA regulation in neurotransmission
Amount £22,950 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description Defining the role of micro RNA regulation in neurotransmission BBSRC Industrial Partnership - CASE award
Amount £78,820 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description Dental Pain Study - assessment of ongoing pain using imaging and genetics
Amount £459,460 (GBP)
Organisation Pfizer Ltd 
Sector Private
Country United Kingdom
Start  
 
Description Developmental change in temperament in preschoolers: implications and etiology (Asherson)
Amount £5,734 (GBP)
Funding ID 1R01HD068435-01A1 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 04/2012 
End 01/2013
 
Description Developmental pathways into adolescent substance abuse: neurophysiologic, genetic and environmental determinants
Amount £1,227,754 (GBP)
Funding ID G0901858 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Dissection of stress vulnerability through gene-environment interactions
Amount £220,428 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Does elevated C-reactive protein predict future psychopathology amongst children exposed to trauma? (Fisher)
Amount £15,652 (GBP)
Funding ID 164-1719 
Organisation The Waterloo Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2013 
End 02/2014
 
Description Dr Christian Muller - MRC Centre Studt - A. Easton
Amount £83,720 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Jonathan Mill - MRC Centre Studt- R. Pidsley
Amount £83,720 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Jonna Kuntsi - MRC DTA Studt - R. Pinto
Amount £89,428 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Leonard Schalkwyk - MRC GENE Studt- K. Malki
Amount £83,720 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Louise Arseneault - MRC DTA Studt - S. Shakoor
Amount £89,428 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dr Sara Jaffee - ESRC Studentship for L. Lysenko
Amount £79,520 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Dyslexia genes and neurological pathways
Amount £85,206 (GBP)
Funding ID 18696 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description EC FP7 funding (Psych CNVs project, PB)
Amount £428,000 (GBP)
Funding ID 223423 
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start  
 
Description EC, Frame work 6 Integrated Project-Reinforcement-related behaviour in normal brain function and psychopathology
Amount £994,623 (GBP)
Funding ID 37286 
Organisation Sixth Framework Programme (FP6) 
Sector Public
Country European Union (EU)
Start  
 
Description ERC Advanced Investigator Grant
Amount £1,752,641 (GBP)
Organisation European Research Council (ERC) 
Sector Public
Country European Union (EU)
Start  
 
Description ESRC 2009 SGDP - Andrew Merwood
Amount £80,910 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description ESRC 2009 SGDP - Elizabeth O'Nions
Amount £80,910 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description ESRC Post - Doctoral fellowship
Amount £83,218 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description ESRC-Physiological and cognitive mediators of gene x environment interaction effects on children's antisocial behaviour
Amount £866,016 (GBP)
Funding ID ES/G020132/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description EU FP6 Contract - APES - Comparative analysis of primate genomes, transcriptomes and proteomes with an emphasis on cognitive capabilities.
Amount £318,906 (GBP)
Funding ID 28594 
Organisation Sixth Framework Programme (FP6) 
Sector Public
Country European Union (EU)
Start  
 
Description EpiTrain - Innovative techniques and models to understand epigenetic regulation in the pathogenesis of common diseases (Mill) EC Framework
Amount £248,954 (GBP)
Funding ID 316758 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 03/2013 
End 02/2017
 
Description Epidemiology of ADHD Pharmacological Treatments in Children and Adults in UK Primary Care
Amount £32,938 (GBP)
Organisation Shire Pharmaceuticals 
Department Shire Development
Sector Private
Country United States
Start  
 
Description Epidemiology of ADHD Pharmacological Treatments in Children and Adults in UK Primary Care/Shire Development INC
Amount £25,000 (GBP)
Organisation Shire Pharmaceuticals 
Department Shire Development
Sector Private
Country United States
Start  
 
Description Epigenetic and Transcriptional Dysregulation in Autism Spectrum Disorder. (Mill)
Amount £125,582 (GBP)
Funding ID 1R01MH094714-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 08/2011 
End 06/2015
 
Description Epigenetic mechanisms of memory storage
Amount £131,550 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Epigenetic pathways to conduct problem trajectories: the role of prenatal and pos (J Mill)
Amount £205,515 (GBP)
Funding ID 1 R01 HD068437-01A1 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 02/2012 
End 01/2015
 
Description Epigenetics of Alzheimer's disease
Amount £92,700 (GBP)
Funding ID ART-PhD2009-3 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Establishing the utility of pharmacogenetic prescribing in psychiatric disorders (C Lewis-Studentship) -M Verbelen
Amount £31,400 (GBP)
Organisation Eli Lilly & Company Ltd 
Sector Private
Country United Kingdom
Start 10/2013 
End 09/2017
 
Description Estimating risks of Schizophrenia across genetic and environmental factors Guys and St Thomas Charitable Foundation
Amount £258,014 (GBP)
Organisation Guy’s & St Thomas’ Charity 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description European Association of Personality Psychology travel scholarship
Amount £330 (GBP)
Organisation European Association of Personality Psychology (EAPP) 
Sector Charity/Non Profit
Country European Union (EU)
Start 01/2010 
End 12/2010
 
Description European Autism Interventions - A Multicentre Study for Developing New Medications (EU-AIMS) - Direct Funding Contribution from Autism Speaks (Schumann)
Amount £460,112 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start 04/2012 
End 03/2017
 
Description European Autism Interventions - a multicentre study for developing new medications (EU-AIMS) (Collier)
Amount £1,497,670 (GBP)
Funding ID 05/09/2215 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 04/2012 
End 03/2017
 
Description Evaluating a methology for the investigation into the effects of discontinuing stimulant medication in a controlled trial, South London and Maudsley (SLAM) Trust R&D
Amount £40,884 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Experimental study to explore potential brain activation changes in children with ADHD after one dose of Atomoxetine compared to Methylphenidate or Placebo children with attention Deficit Hyperactivity Disorder (ADHD)
Amount £40,000 (GBP)
Organisation Valspar 
Sector Public
Country United States
Start  
 
Description FP6 Specific Targeted Research Project - A Large Scale Genome-Wide Association Study of Schizophrenia Addressing Variation in Expressivity and Contribution from Environmental Factors (SGene)
Amount £279,485 (GBP)
Funding ID 37761 
Organisation Sixth Framework Programme (FP6) 
Sector Public
Country European Union (EU)
Start  
 
Description Familial transmission of emotional development: A children of twins approach
Amount £195,440 (GBP)
Organisation The Leverhulme Trust 
Sector Academic/University
Country United Kingdom
Start  
 
Description Familial transmission of emotional development: A children of twins approach (Eley)
Amount £195,440 (GBP)
Funding ID RPG-210 
Organisation The Leverhulme Trust 
Sector Academic/University
Country United Kingdom
Start 03/2012 
End 02/2015
 
Description Fellowship in Mental Health Statistics with especial emphasis on genetics
Amount £135,422 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Financial support for FP7 application SGENeSIS
Amount £3,491 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Foundation Peters Research Grant
Amount £140,000 (GBP)
Organisation Hinrichsen Foundation 
Sector Charity/Non Profit
Country Unknown
Start 09/2016 
End 08/2020
 
Description From genes to brain behavior: A multidisciplinary investigation of the autistic triad./National alliance for Autism research
Amount £41,669 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description Functional Correlates and Genetic Risk for Neuropsychiatric Traits Associated with Rolandic Epilepsy
Amount £99,906 (GBP)
Funding ID WF11 
Organisation Epilepsy Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description G1100583 - Low coverage sequencing for the detection and analysis of genomic structural variants in schizophrenia (Dobson)
Amount £1,015,920 (GBP)
Funding ID G1100583 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2011 
End 09/2014
 
Description GEnG*EED - Environment, genetics and endophenotypes in eating disorders and obesity
Amount £141,647 (GBP)
Funding ID 254774 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description GHCA: Genetics of High Cognitive Abilities (Plomin)
Amount £2,068,331 (GBP)
Funding ID 06/09/2708 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 04/2012 
End 03/2017
 
Description Gene x gene and gene x environment interactions underlying speech, language and reading development - G0800523
Amount £6,099 (GBP)
Funding ID G0800523 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Gene-Environment Interplay in Children`s Resilience to Harsh, Non-Supportive Parenting
Amount £186,407 (GBP)
Organisation Nuffield Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Gene-environmental interactions in youth mental health visiting fellowship (Arseneault)
Amount £990,000 (GBP)
Funding ID NF120069 
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2014
 
Description Genetic causes of Neurodevelopmental Delay in Children: translation and interpretation of novel pathogenic copy number variants and novel rare exonic mutations into clinical genetic practice
Amount £24,431 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Genetics of mathematical cognition and disabilities
Amount £410,156 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Genetics, school environment and cognitive development
Amount £404,957 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Genetics, school environment and cognitive development
Amount £234,035 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2010 
End 12/2010
 
Description Genome-wide association study - Wellcome Trust
Amount £55,727 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description GlaxoSmithKline -FMRI study comparing brain functional activation before and after 8 weeks of treatments with placebo
Amount £504,393 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description Glutamate and GABA in adults with autism; an in vivo study using magnetic resonance spectroscopy
Amount £354,175 (GBP)
Funding ID 091300 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Health risk trajectories across adolescence: Understanding gender differences
Amount £11,732 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description HeroGen - Genetics of Heroin Dependence (Asherson)
Amount £158,824 (GBP)
Funding ID 15/12/2726 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 10/2012 
End 09/2014
 
Description How does childhood maltreatment lead to depression in adults? A molecular study on inflammatory and metabolic pathways using the South East London Community Health (SELCoH) sample (Caspi Moffitt Danese CoPI)
Amount £50,000 (GBP)
Funding ID McGregor 97 
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start 06/2011 
End 05/2014
 
Description IMAGEN Integrated Project - Reinforcement-related behaviour in normal brain function and psychopathology.
Amount £356,770 (GBP)
Funding ID 37286 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description IMAGEN W.P7 - Reinforcement-related behaviour in normal brain function and psychopathology
Amount £174,070 (GBP)
Funding ID 37286 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description IMAGEN W.P8 - Reinforcement-related behaviour in normal brain function and psychopathology
Amount £195,412 (GBP)
Funding ID 37286 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description IN-VIVO MRS ASSAY OF BRAIN GLUTAMATE AND DRUG RESPONSE IN HUMANS AND A MOUSE MODEL OF AUTISM (Fernandes)
Amount £32,829 (GBP)
Funding ID 06/04/1922 
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start 12/2012 
End 11/2014
 
Description INTACT- Individually Tailored Stepped care for women with eating disorders
Amount £326,237 (GBP)
Funding ID 35988 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Identical twins discordant for autism: Epigenetic (DNA methylation) biomarkers of non-shared environmental influences
Amount £131,804 (GBP)
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Identification of novel biomarkers for disease progression in Alzheimer's disease (Newhouse)
Amount £131,273 (GBP)
Funding ID No4 
Organisation Johnson & Johnson 
Department Janssen-Cilag
Sector Private
Country Global
Start 10/2013 
End 09/2017
 
Description Identifuing generic and enviromental risk factors and their interplay for achivement at school-Award for Claire Haworth
Amount £175,368 (GBP)
Funding ID G0802681 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Identifying patterns of genome-wide association in the development of cognitive, behavioural and psychiatric disorders
Amount £250,000 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Imitation in Autism
Amount £57,922 (GBP)
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Influence of genes & childhood experiences on the onset & outcome of Psychosis
Amount £48,900 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Information processing, IQ and social learning in ASD
Amount £4,810 (GBP)
Organisation King's College London 
Department Social Psychiatry
Sector Academic/University
Country United Kingdom
Start  
 
Description Initial organizational workshop to establish a consortium on the genetics of High Cognitive Abilities
Amount £4,074 (GBP)
Organisation The John Templeton Foundation 
Sector Academic/University
Country United States
Start 01/2007 
End 12/2007
 
Description Intellectual Development in Tuberous Sclerosis (Bolton)
Amount £63,162 (GBP)
Funding ID TRUST/RNA/AC/KW/36/4901 
Organisation Baily Thomas Charitable Fund 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2012 
End 03/2014
 
Description Interaction between genes and psychosocial factors in the aetiology and outcomes of psychotic disorders (Fisher)
Amount £76,090 (GBP)
Funding ID psychosis 1 
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start 04/2012 
End 03/2015
 
Description Interaction between genetic risk and chidhood adversity in the development of psychosis and depression
Amount £160,628 (GBP)
Funding ID G0802674 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description International Study of Genetic Factors in Exposure Treatments of Anxiety Disorders
Amount £301,248 (GBP)
Organisation Alexander von Humboldt Foundation 
Sector Public
Country Germany
Start  
 
Description International Study of Genetic Factors in Exposure Treatments of Anxiety Disorders (Eley)
Amount £301,248 (GBP)
Organisation Alexander von Humboldt Foundation 
Sector Public
Country Germany
Start 09/2011 
End 09/2015
 
Description International Travel Grant 2010
Amount £4,000 (GBP)
Organisation The Royal Society 
Sector Academic/University
Country United Kingdom
Start  
 
Description Intervention within the British Autism Study of Infant Siblings (i-BASIS)
Amount £75,910 (GBP)
Funding ID 7267 
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Intervention within the British Autism Study of Infant Siblings (i-BASIS) - Bolton Booth
Amount £82,910 (GBP)
Funding ID #7267 
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2011 
End 03/2013
 
Description Investigating the phenotype and genetic architecture of myoclonic astatic epilepsy (Collier)
Amount £251,485 (GBP)
Funding ID MR/J011231/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2015
 
Description Investigation of Copy Number Variation as modifier loci in the co-morbidities and phenotype of Rolandic Epilepsy (Collier)
Amount £48,400 (GBP)
Funding ID 164/1547 
Organisation The Waterloo Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2012 
End 12/2013
 
Description Investigation of heritability and the genetic basis of subtypes of schizophrenia: a collaborative study
Amount £35,866 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description Investigation on contrast effects in children with autism
Amount £89,030 (GBP)
Funding ID ES/G035679/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Is childhood cruelty to animals a marker of child abuse in a population-based sample of twins
Amount £2,810 (GBP)
Organisation Royal Society for the Prevention of Cruelty to Animals 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2009 
End 12/2009
 
Description Is there a shared heritability for the type 2 diabetes and depression association? Fellowship (Rijsdijk, Lewis)
Amount £203,821 (GBP)
Organisation Novo Nordisk 
Department Novo Nordisk UK Research Foundation
Sector Charity/Non Profit
Country United Kingdom
Start 02/2014 
End 12/2017
 
Description KCL Primerdesign Student Sponsorship Stipend Top-Up for Georgia Powell-Smith
Amount £250 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Karen Ashwood Student Maintenance Grant
Amount £65,195 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Klaus J. Jacobs Research Prize: Best Practice Award (Caspi Moffitt)
Amount £344,045 (GBP)
Organisation Jacobs Foundation 
Sector Charity/Non Profit
Country Switzerland
Start 01/2011 
End 12/2015
 
Description Laboratory and clinical validation of a minimally-invasive assay to study the genomic fingerprint of stress (Danese Plomin)
Amount £81,689 (GBP)
Funding ID 1R21HL109396-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 08/2011 
End 07/2013
 
Description Laboratory and clinical validation of a minimally-invasive assay to study the genomic fingerprint of stress.
Amount £81,689 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Linking Adolescent cannabis exposure to schizophrenia: the role of DNA methylation
Amount £25,712 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description Linking Genetic Variation to Brain Anatomy and Behaviour in ASD-A follow on to the Autism Imaging Multicentre Project
Amount £37,500 (GBP)
Organisation Autistica 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Longtitudinal changes in DNA methylation: a study to investigate the dynamics of epigenetic discordance between genetically-identical twins (University of London (Central research funds)
Amount £5,300 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description MQ Fellows Award (Fisher) MQ Transforming Mental Health
Amount £225,000 (GBP)
Organisation MQ Transforming Mental Health 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2014 
 
Description MRC - Autism genetics and normal variation in cognition and behavior
Amount £110,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC - Contribution of genetics and early cognitive and emotional development to attention problems in middle childhood G0800054
Amount £201,974 (GBP)
Funding ID G0800054 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC - Cortical Morphometry in Autism Spectrum Disorder G0701370
Amount £273,108 (GBP)
Funding ID G0701370 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC - Developmental pathways into adolescent substance abuse: neurophysiologic, genetic and environmental determinants G0901858
Amount £977,753 (GBP)
Funding ID G0901858 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC - Developmental trajectories of psychosis in population-based samples: interplay between early adversity and familial risk - G1002366
Amount £275,864 (GBP)
Funding ID G1002366 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC - Low coverage sequencing for the detection and analysis of genomic structural variants in schizophrenia G1100583
Amount £1,015,920 (GBP)
Funding ID G1100583 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC - Next generation gene hunting in ALS G0900688
Amount £1,189,644 (GBP)
Funding ID G0900688 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC - Psychobiological sequelae of cumulative exposure to violence: The Environmental Risk Longitudinal Twin Study - G1002190
Amount £2,738,755 (GBP)
Funding ID G1002190 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC 09 SGDP DTA - Hannah Grayton
Amount £92,794 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description MRC 2009 SGDP Centre - Agnieszka Kepa
Amount £86,350 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description MRC 2009 SGDP Centre - Maciej Trazaskowoski
Amount £86,350 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description MRC 2009 SGDP Centre - Timothy Powell
Amount £86,350 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2009 
End 09/2010
 
Description MRC 2009 SGDP DTA - C Cheung
Amount £92,794 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description MRC 2009 SGDP Stats Gen - Jennifer Pararajasingham
Amount £63,640 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2009 
End 09/2012
 
Description MRC Centre Studentship for Caroline Skirrow
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC Centre Studentship for Chloe Wong
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC Centre Studentship for Corina Greven
Amount £65,273 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description MRC Centre Studentship for Helena Zavos
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC Centre Studentship for Jemma Day
Amount £86,907 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC Centre Studentship for Robert Keers
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC DTA Studentship for Hannah Wiltshire
Amount £86,907 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC DTA Studentship for Rachel Kember
Amount £86,907 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC G1002366 Developmental trajectories of psychosis in population-based samples: interplay between early adversity and familial risk (Fisher, Moffitt)
Amount £275,864 (GBP)
Funding ID G1002366 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 09/2011 
End 09/2014
 
Description MRC New Investigator Award (Ronald)
Amount £450,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC Social, Genetic and Developmental Psychiatry Centre (MRC Centenary Award) - (Fisher)
Amount £15,000 (GBP)
Funding ID G9817803-E02/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 09/2012 
End 09/2013
 
Description MRC Social, Genetic and Developmental Psychiatry Centre. The Centenary Award (C Wong)
Amount £15,000 (GBP)
Funding ID G9817803-E02/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2012 
End 09/2015
 
Description MRC Social, Genetic and Developmental Psychiatry Centre. The Centenary Award (Haworth and Davis)
Amount £15,000 (GBP)
Funding ID G9817803-E02/1 
Organisation Medical Research Council (MRC) 
Department Medical Research Foundation
Sector Charity/Non Profit
Country United Kingdom
Start 10/2012 
End 08/2013
 
Description MRC studentship for Stephanie Lietz
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2007 
End 09/2011
 
Description MRC studentship for Susanne Pfeifer
Amount £81,735 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 09/2011
 
Description Maintenance of the NRXN1 knockout mouse colony (Fernandes)
Amount £25,000 (GBP)
Organisation Eli Lilly & Company Ltd 
Sector Private
Country United Kingdom
Start 01/2013 
End 01/2014
 
Description Mapping genetic - epigenetic interactions across the gerome (University of London (Central research funds))
Amount £3,500 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Medical Research Council-A population-based twin-study of autism spectrum disorders: genetic and environmental sources of cognitive and clinical heterogeneity G0500870
Amount £569,527 (GBP)
Funding ID G0500870 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Medical Research Council-Adolescent conduct problems: a biosocial model of risk G0500953
Amount £583,524 (GBP)
Funding ID G0500953 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Medical Research Council-Mental disorders from childhood to adulthood: The Dunedin Study age 38 followup G0601483
Amount £785,827 (GBP)
Funding ID G0601483 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Mental Disorders from childhood to adulthood
Amount £1,243,737 (GBP)
Funding ID G0601483 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Methylomic profiling in schizophrenia: Towards an integrated genetic-epigenetic approach (Schalkwyk)
Amount £112,451 (GBP)
Funding ID MR/K013807/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 06/2013 
End 05/2016
 
Description Mood instability in adult Attention Deficit/Hyperactivity Disorder
Amount £76,216 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Moodinflame - Early diagnosis, treatment and prevention of mood disorders targeting the activated inflammatory response system
Amount £386,803 (GBP)
Funding ID 222963 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description NIH Competing Research Application (R01 Maths)
Amount £1,134,051 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description NIH Competing Research Application (R21 Danese)
Amount £172,700 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description NIHR Biomedical Research Centre (BRC)-Functional characterisation of Ras-Grf2 gene variants in alcohol addiction and its treatment.
Amount £11,400 (GBP)
Organisation National Institute for Health Research 
Department NIHR Comprehensive Biomedical Research Centre, Guy's and St Thomas
Sector Public
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Analysis of neurotransmitter-induced transcriptional changes in human genotype-specific lymphoblastoid cell lines (pilot grant)
Amount £19,750 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-C-Reactive protein as a salivary marker of inflammation among children: a laboratory and clinical validation.
Amount £19,940 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Identification of genetic variations moderating alcohol consumption through sequencing of candidate genomic regions.
Amount £20,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Paternal age effects in autism: Exploring epigenetic mechanisms
Amount £20,000 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Transcriptomic analyses for treatment response to fentanyl in humans
Amount £9,977 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health (Ref: BRC)-Transcriptomic profiles of inflammatory cytokines and receptors as biomarkers for major depressive disorder
Amount £17,584 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Biomedical Research Centre for Mental Health Impact of mood instability and ADHD on adult behavioural disorders and psychopathology, NIHR/SLAM NHS Trust
Amount £76,216 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR Programme grant
Amount £2,000,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description NIHR Senior Investigator Award 2011 - Bolton
Amount £60,000 (GBP)
Funding ID 2011 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2011 
End 03/2015
 
Description NIMH-The Psychiatric GWAS Consortium: Integrated and Coordinated GWAS Meta-Analyses
Amount £52,894 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description National Institute of Health Research (BRC)-Translational research: Mental disorders in young people
Amount £748,971 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description National Institutes of Health (R01 School Environment renewal)
Amount £822,000 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Neural correlates of empathy and perspective taking in adolescents with psychopathic traits and adolescents with autism spectrum disorder - Awarded to PhD student E O Nions (University of London (Central Research Funds))
Amount £5,340 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Neurobiological Correlates of Antidepressant Response After Treatment in Subjects with Major Depressive Disorder
Amount £14,002 (GBP)
Organisation Eli Lilly & Company Ltd 
Sector Private
Country United Kingdom
Start  
 
Description Next Generation Gene Hunting in ALSA
Amount £100,000 (GBP)
Organisation Motor Neurone Disease Association (MND) 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Next generation gene hunting in ALS
Amount £87,346 (GBP)
Organisation ALS Association 
Sector Charity/Non Profit
Country United States
Start  
 
Description Novel Methods leading to New Medications in Depression and Schizophrenia (NEWMEDS)
Amount £2,347,840 (GBP)
Funding ID 115008 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description OPTIMISE Optimisation of Treatment and Management of Schizophrenia in Europe
Amount £1,421,520 (GBP)
Funding ID 242114 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Omega-3 Fatty Acids Supplementation for Adolescent Boys with Attention Deficit Hyperactivity Disorder A Double-blind, Randomized Controlled Trial/The Mother and Child Foundation
Amount £124,154 (GBP)
Organisation Mother and Child Foundation 
Sector Charity/Non Profit
Country India
Start  
 
Description Optimisation of sampling for CYP genotyping and analysis of CYP genotype as a predictor of steady state atomoxetine dose
Amount £10,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Origins of learning difficulties and behaviour problems: from behavioural genetics to behavioural genomics
Amount £1,868,807 (GBP)
Funding ID G0901245 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Pathways into persistent offending: the relative contribution of ADHD and substance misuse
Amount £271,233 (GBP)
Organisation Shire Pharmaceuticals 
Department Shire Development
Sector Private
Country United States
Start  
 
Description Pathways into persistent offending: the relative contribution of ADHD and substance misuse (Asherson CoPI)
Amount £271,233 (GBP)
Funding ID #8000054949 
Organisation Shire Pharmaceuticals 
Department Shire Development
Sector Private
Country United States
Start 06/2011 
End 05/2014
 
Description Persistent fatigue induced by interferon-alpha: a new immunological model for chronic fatigue syndrome (Dobson)
Amount £373,075 (GBP)
Funding ID MR/J002739/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 08/2012 
End 08/2015
 
Description Pharmacogenetic Pilot Study of Opioid Substitution Treatment
Amount £36,069 (GBP)
Organisation Reckitt Benckiser 
Sector Private
Country United Kingdom
Start  
 
Description Pharmacogenomic biomakers as a clinical decision making tools for clozapine treatment of schizophrenia. CRESTAR (RTD) - (Collier)
Amount £576,145 (GBP)
Funding ID 29/06/2664 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 11/2011 
End 10/2015
 
Description Pharmacogenomic biomarkers as clinical decision making tools for clozapine treatment of schizophrenia. CRESTAR (OTHER) (Collier)
Amount £85,802 (GBP)
Funding ID 279227 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 11/2011 
End 10/2015
 
Description Pharmacogenonmic biomarkers as clinical decision making tools for clozapine treatment of schizophrenia. CRESTAR (MNGT) (Collier)
Amount £11,361 (GBP)
Funding ID 29/06/2664 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 11/2011 
End 10/2015
 
Description Physiological and Cognitive Mediators of Gene x Environment Interaction Effects on Children`s Antisocial Behaviour
Amount £421,539 (GBP)
Funding ID ES/G020132/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Positive genetics: The nature and Nurture of Wellbeing in Adolescence
Amount £258,002 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start  
 
Description Positive genetics: The nature and Nurture of Wellbeing in Adolescence (Haworth)
Amount £260,025 (GBP)
Funding ID pf110044 
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 09/2011 
End 09/2014
 
Description Post Doctoral Fellowship for Kathryn Asbury
Amount £217,737 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start  
 
Description Prediction and analysis of regulatory SNP MAP of major depressive disorder - via the University of Aberdeen
Amount £337,054 (GBP)
Funding ID G0701003 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Prediction of prodromal schizophrenia using a triad of early risk factors in a longitudinal cohort of children (Fisher)
Amount £30,781 (GBP)
Funding ID Margaret Temple (2012) 
Organisation British Medical Association (BMA) 
Sector Learned Society
Country United Kingdom
Start 03/2013 
End 03/2016
 
Description Preschool Autism Communication Trial (PACT)
Amount £12,706 (GBP)
Funding ID G0401546 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2010 
End 12/2010
 
Description Preterm birth as a risk factor for attention deficit hyperactivity disorder: a cognitive-neurophysiological sibling study (Kuntsi, Asherson, Rijsdijk)
Amount £169,944 (GBP)
Funding ID GN2080 
Organisation Action Medical Research 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2013 
End 03/2016
 
Description Production of a paper on aripiprazole and anti-psychotic weight-gain, and of a review on the use of aripiprazole in schizophrenia in both adults and adolescents/Bristol Myers Squibb
Amount £20,426 (GBP)
Organisation Bristol-Myers Squibb 
Sector Private
Country United States
Start 01/2007 
End 12/2007
 
Description Prof Patrick Bolton - MRC Centre studt - C. Tye
Amount £83,720 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Prof Robert Plomin - ESRC Stud - K. Hanscombe
Amount £83,720 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2008 
End 09/2012
 
Description Provision of equipment and expertise/Sichuan University
Amount £10,946 (GBP)
Organisation Sichuan University 
Sector Academic/University
Country China
Start  
 
Description PsychDPC: Psychiatric diagnostic and prevention consortium (C Lewis)
Amount £132,291 (GBP)
Funding ID 15/08/2683 
Organisation European College of Neuropsychopharmacology (ECNP) 
Sector Learned Society
Country European Union (EU)
Start 01/2012 
End 12/2015
 
Description Psychiatric disorder and accelerated aging: The Dunedin Multidisciplinary Health and Development Longitudinal Cohort Study (Moffitt Caspi)
Amount £1,032,424 (GBP)
Funding ID MR/K00381X/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2016
 
Description Psychiatry Research Trust - DNA methylation and adolescent depression: an MZ differences study
Amount £47,800 (GBP)
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Psychiatry Research Trust - How does childhood maltreatment lead to depression in adults? A molecular study on inflammatory and metabolic pathways using the South East London Community Health (SELCoH) sample
Amount £50,000 (GBP)
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Psychosocial resilience in adolescent offspring of mothers with depression : testing causal mechanisms (Maughan via Cardiff)
Amount £5,006 (GBP)
Funding ID ES/J011657/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2013 
End 12/2014
 
Description Pyrosequencer for quantitative DNA methylation profiling in Alzheimer's Disorder
Amount £20,000 (GBP)
Funding ID ART-EG2010A-2 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2010 
End 12/2010
 
Description Quantitative review of risks for substance misuse
Amount £3,973 (GBP)
Organisation Academy of Medical Sciences (AMS) 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2006 
End 12/2006
 
Description ROAMER- A Roadmap for Mental Health Research in Europe (Schumann)
Amount £88,317 (GBP)
Funding ID HEALTH-F3-2011-282586 
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start 10/2011 
End 09/2014
 
Description Real-time functional magnetic resonance imaging (fMRI) Neurofeedback in children with ADHD (Attention Deficit Hyperactivity Disorder) (Rubia)
Amount £197,365 (GBP)
Funding ID 1890 
Organisation Action Medical Research 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2012 
End 02/2015
 
Description Replication of depression HiTDIP findings for selected genes in the depression case control sample collected at IOP-consultancy
Amount £56,160 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description Replication of proteome based plasma biomarkers identified by using the SomaLogic aptamer platform (Sattlecker)
Amount £9,000 (GBP)
Funding ID EPI Pilot Award 
Organisation King's College London 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 11/2012 
End 03/2013
 
Description Research grant Haruv Institute
Amount £43,849 (GBP)
Organisation Harbin Institute of Technology 
Sector Academic/University
Country China
Start 09/2016 
End 09/2017
 
Description Review of interventions for malteated children and adolescents (Fisher)
Amount £45,717 (GBP)
Funding ID RK 735943478 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 02/2013 
End 07/2014
 
Description Royal Society International Travel Grant
Amount £3,950 (GBP)
Organisation The Royal Society 
Sector Academic/University
Country United Kingdom
Start  
 
Description Royal Society Rosalind Franklin Award 2011 - Raising primary-school children's awareness of women in SET through a new series of short picture books (Happe)
Amount £30,000 (GBP)
Funding ID RFA11/ER 
Organisation The Royal Society 
Sector Academic/University
Country United Kingdom
Start 10/2011 
End 07/2013
 
Description Russian Federation Grants for State support for research (Kovas)
Amount £3,100,000 (GBP)
Organisation Government of Russia 
Sector Public
Country Russian Federation
Start  
 
Description Schizophrenia and Advancing Paternal Age: Clinical and Molecular Characteristics
Amount £40,000 (GBP)
Organisation British Medical Association (BMA) 
Sector Learned Society
Country United Kingdom
Start  
 
Description Social Inequality and Children's Mental Health
Amount £209,414 (GBP)
Funding ID ES/H034897/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Social Motivation in Autism Spectrum Disorders (Coralie Chevallier)
Amount £78,360 (GBP)
Funding ID ES/G020523/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Social, psychological and genetic resilience to adversity in bipolar disorder
Amount £159,588 (GBP)
Funding ID ES/H04678X/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description Socio-economic disparities in Alcohol and Drug Abuse in Adoloscents and Young adults
Amount £4,500 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description Socio-economic disparities in alcohol and drug use among adolescents and young adults
Amount £2,000 (GBP)
Organisation King's College London 
Department Social Psychiatry
Sector Academic/University
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description Specificity and familiability of EEG parameters in ADHD and ASD/Steel Charitable Trust
Amount £2,000 (GBP)
Organisation Steel Charitable Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Specificity and familiality of EEG parameters in ADHD and ASD
Amount £26,728 (GBP)
Organisation The Waterloo Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Start up funds to prepare a MRC research grant on the role of circadian rhythm genes on substance use disorders/Psychiatry Research Trust
Amount £20,440 (GBP)
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Studentship for Inti Pedroso, Biomedical Research Centre (BRC)
Amount £52,138 (GBP)
Organisation South London and Maudsley (SLAM) NHS Foundation Trust 
Department NIHR Maudsley Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description Suicidality: Treatment occurring in paediatrics (STOP)
Amount £71,498 (GBP)
Funding ID 261411 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Systematic Analysis of Cocaine Target Genes in Cocaine Addiction/Psychiatry Research Trust
Amount £23,000 (GBP)
Organisation King's College London 
Department Psychiatry Research Trust
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description TRiP: Translational Research in Psychiatry MC IRSES (Breen)
Amount £231,186 (GBP)
Funding ID FP7-PEOPLE-2011-IRSES 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 06/2012 
End 05/2016
 
Description TWIST: The Twins Wellbeing Intervention Study (Haworth)
Amount £9,900 (GBP)
Funding ID SG112183 
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 04/2012 
End 09/2013
 
Description The Biological mechanism of somatic symptoms in depression;The role of polyunsaturated fatty acids
Amount £37,531 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description The Colombo Twin and Singleton Study (CoTaSS) follow up
Amount £246,263 (GBP)
Funding ID 093206 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description The Genetics and Pharmacogenetics of Methamphetamine Abuse and Psychosis
Amount £27,219 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description The Psychiatric GWAS Consortium: Integrated & Coordinated GWAS Meta-Analyses 1/5
Amount £42,714 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description The adult consequences of being bullied in childhood. A 45-year prospective epidemiological study (Arseneault)
Amount £133,294 (GBP)
Funding ID MD120015 
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 12/2012 
End 12/2013
 
Description The effect of intranasal oxytocin on social emotional functioning in anorexia nervosa (G Kalsi)
Amount £33,980 (GBP)
Organisation Swiss Anorexia Nervosa Foundation 
Sector Charity/Non Profit
Country Global
Start 01/2013 
End 10/2013
 
Description The genetics of High Cognitive Abilities
Amount £132,463 (GBP)
Organisation The John Templeton Foundation 
Sector Academic/University
Country United States
Start  
 
Description The relationship between imitation and social skills and disabilities
Amount £82,329 (GBP)
Funding ID ES/F034601/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description The relationship of Essential Fatty Acids to cognitive, electrophysiological and behavioural function in adults with attention deficit hyperactivity disorder and controls
Amount £101,149 (GBP)
Organisation Galencia 
Department Vifor Pharma UK
Sector Private
Country United Kingdom
Start  
 
Description The relationship of Essential Fatty Acids to cognitive, electrophysiological and behavioural function in adults with attention deficit hyperactivity disorder and controls - Asherson
Amount £101,148 (GBP)
Organisation Galencia 
Department Vifor Pharma UK
Sector Private
Country United Kingdom
Start 10/2011 
End 09/2015
 
Description The role of antisocial friends in the development of antisocial behaviour during adolescence (Eley - Fellowship)
Amount £85,328 (GBP)
Funding ID ES/I036524/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 06/2011 
End 05/2014
 
Description The role of antisocial friends in the development of antisocial behaviour during adolescence.
Amount £85,328 (GBP)
Funding ID ES/I036524/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start  
 
Description The role of epigenetic processes in mediating the molecular and behavioural responses to stress in the dentate gyrus`
Amount £66,291 (GBP)
Funding ID BB/G02507X/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start  
 
Description Transgenerational effects of advanced paternal age on offspring (Fernandes)
Amount £18,247 (GBP)
Funding ID 0285-3965-4609 
Organisation Icahn School of Medicine at Mount Sinai 
Sector Academic/University
Country United States
Start 06/2013 
End 05/2014
 
Description Transition to Young Adulthood in Autism Spectrum Disorder: Mental Health and Wellbeing in a Population-Based Sample of Twins (Happe Colvert)
Amount £59,629 (GBP)
Funding ID TRUST/RNA/AC/KW/2415/4904 
Organisation Baily Thomas Charitable Fund 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2013 
End 05/2015
 
Description Translating gene-environment interaction from aetiology to personalised medicine for anxiety and depression - Fellowship (Keers)
Amount £270,776 (GBP)
Funding ID MR/K021281/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 07/2013 
End 07/2016
 
Description US NIMH-Molecular epigenetic studies of major depression US NIMH
Amount £32,171 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description US National Institute of Child Health and Human Development- Genetics of general and specific mathematics disabilities
Amount £387,075 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2009 
End 12/2009
 
Description US National Institute of Child Health and Human Development-Reading disability QTLs: Pooled DNA on microarrays
Amount £539,533 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description Understanding and influencing pupils' choices as they prepare to leave school (Plomin)
Amount £117,942 (GBP)
Funding ID EDU/40881 
Organisation Nuffield Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2012 
End 09/2014
 
Description Understanding how genomic, transcriptomic and proteomic variation is associated with metabolic changes in Alzheimer's Disease (Dobson)
Amount £199,777 (GBP)
Funding ID 15/06/1900 
Organisation Alzheimer’s Society 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2012 
End 09/2015
 
Description Understanding the neuroendocrine regulation of weight gain psychosis
Amount £32,336 (GBP)
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start  
 
Description Understanding the role of stress in the cognitive abnormalities of psychosis
Amount £78,573 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start  
 
Description Unifying genetic and epigenetic approach to psychiatric disorders in children and adolescents : Analysis of the human brain. (Schumann)
Amount £50,667 (GBP)
Funding ID 259-2012-23 
Organisation Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS) 
Sector Public
Country Switzerland
Start 09/2012 
End 12/2013
 
Description University of London (Central Research Funds) Can cerebral blood flow predict response to treatment in first episode psychosis?
Amount £6,615 (GBP)
Organisation King's College London 
Sector Academic/University
Country United Kingdom
Start  
 
Description Vacation Scholarship of Francesca Silman
Amount £1,480 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description Validation of the classical CUMS (Chronic Unpredictable Mild Stress) model - Behavioural Validation (Fernandes)
Amount £218,718 (GBP)
Organisation Johnson & Johnson 
Department Janssen-Cilag
Sector Private
Country Global
Start 01/2013 
End 12/2016
 
Description Validation of the classical CUMS (Chronic Unpredictable Mild Stress) model - Molecular Validation Studentship (Fernandes)
Amount £142,473 (GBP)
Funding ID No.2 
Organisation Johnson & Johnson 
Department Janssen-Cilag
Sector Private
Country Global
Start 01/2014 
End 12/2017
 
Description W.P7-IMAGEN Integrated Project Reinforcement-related behaviour in normal brain function and psychopathology
Amount £268,371 (GBP)
Funding ID 37286 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Wellcome Trust VIP Award-Integrating Molecular and Bioinformatic Genetic Studies in stimulant Abuse
Amount £50,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2007 
End 12/2007
 
Description Whole genome analysis of copy number variation in a large case control study of recurrent depression
Amount £215,062 (GBP)
Funding ID 236858 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Whole genome and exome sequencing of families with bipolar disorder and depression Fellowship (Alsabban, Breen)
Amount £182,807 (GBP)
Organisation Government of Saudi Arabia 
Sector Public
Country Saudi Arabia
Start 12/2012 
End 12/2014
 
Description Why do children who are bullied manifest early-onset mental health problems? A genetic and experimental investigation
Amount £132,670 (GBP)
Organisation Jacobs Foundation 
Sector Charity/Non Profit
Country Switzerland
Start  
 
Description Work Package WP8 of NEWMEDS, European Commision Innovative Medicines Initiative
Amount £677,360 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Title HIGH PERFORMANCE COMPUTING (HPC) CLUSTER at the MRC SGDP Centre for BioInformatics 
Description Bioinformatics involves making sense of high-dimensional biological data (e.g., genomic, transcriptomic, and proteomic information) and is thus critical for the Centre's long-term strategy of understanding pathways between genes and behaviour. Although several Centre members are highly knowledgeable about bioinformatics, the goal of the bioinformatics resource and the High Performance Computing Cluster is to provide expertise for the Centre community. The resource is led by Dr Leo Schalkwyk and is supported by two Centre-funded posts, one for bioinformatics (Dr Matthew Davies who was employed in September 2008) and one for programming and co-ordinating the Centre's Linux cluster which currently links 31 compute nodes and provides 64 AMD Opteron 64-bit CPUs with 82 Gb RAM (Mr Stuart Newman). Bioinformatics applications serve two main functions: data integration and data analysis. The cluster is vital to provide both capacity and speed: capacity to store, integrate and distribute large databases, and speed to perform compute-intensive calculations. The cluster is crucial not only for bioinformatics analyses but also for statistical genetics such as analyses of microarray data, meta-analyses and quantitative genetic maximum-likelihood structural equation analyses. Other key issues that are addressed by the team include bioinformatics approaches to the analysis of genome-wide association studies (GWAS) both by pooling and individual genotyping, the use of machine-learning techniques for data integration in interpreting GWAS results, and studies of correlational structure of gene expression profiles across tissues using mouse reference populations. Three Centre PhD students are also helping to grow this resource 
Type Of Material Improvements to research infrastructure 
Year Produced 2007 
Provided To Others? Yes  
Impact In addition to its support role, two examples of major substantive research programmes for the bioinformatics team are to compare gene expression profiles in brain and blood and to assess gene expression profiles as they respond to environmental changes including responses to drugs. 
 
Title MRC SGDP Centre Labs Management Systems 
Description Bernard Freeman has continued to develop a range of software systems that could have potential for technology transfer. All the systems have improved to the point where there could be interest from commercial laboratories. The barcode tracking system for managing samples has expanded tremendously during the last five years to allow more functionality, flexibility and ease of use and is currently undergoing a significant redevelopment to turn it into a commercially attractive package. The software link between the tracking system and our robotics platforms has also expanded to now allow the incorporation of a hotel storage system allowing very large numbers of samples to be handled by the system without user intervention. The SGDP Laboratories have taken the first steps toward gaining accreditation status which will further allow them to carry out specialized commercial genotyping services such as zygosity testing and specific tests (such as for drug metabolising status). The laboratories are also in the process of developing a series videos that will be available as an online training resource. 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact These developments will eventually cover all aspects of laboratory work carried out at the Centre and we are hoping for this to not only be a useful resource for the Centre but also of potential commercial value. The processes and procedures developed have helped in the development of other labs across Kings College London and at other Higher Education Facilities 
 
Title New tools for pathway analysis of genetic data and CNS pathway 
Description Dr Gerome Breen is collaborating on several commercial projects. One is with GeneGo and J&J to devlop new tools for pathway analysis of genetic data and CNS pathway. This is three year project and will result in IOP having first access and use of annotation and tools developed and a perpetual license to Metacore's advanced software and tools. 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact IOP having first access and use of annotation and tools developed and a perpetual license to Metacore's advanced software and tools. Dr Breen is also coinvestigator on the MRC-GSK funded Genome-Wide Aassociation Study for Major Depression and genetics coordinator for the NIHR Biomedical Research Centre for Mental Health, the lab core of which is in the SGDP Centre Labs 
 
Description - Emerald Logic, (US SME), Patrick Lilley (R Dobson) 
Organisation Emerald Logic
Country United States 
Sector Private 
PI Contribution Dr Richard Dobson's BRC Bioinformatics research team based at the SGDP Centre provides the sharing of datasets
Collaborator Contribution Patrick Lilley at Emerald Logic, (US SME) contributes analysis methods
Impact Our collaborator is also on multiple grant applications of Dr Richard Dobson's team
Start Year 2012
 
Description A MRI study on a sub sample of the Gendep Human Pharmacogenetics study 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution The study was initiated with funding from GSK to attempt to relate phenotypic characteristics, candidate genotypes and structural and functional MRI brain scans in depressed subjects.
Impact The study has been continued as part of the NIHR Biomedical Research Centre ( BRC) biomedical technologies theme. Fifty subjects who were part of the GENDEP or DeCC studies have so far been scanned. Preliminary analyses of hippocampal volume and shape in relation to 5HTTLPR and DBNF genotypes are currently underway. The study is an example of Centre projects that integrate brain imaging and genomics.
Start Year 2007
 
Description A genome scan for quantitive loci for early hyperactivity 
Organisation Nuffield Foundation
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution A collaboration to examine the genome scan in order to identify the loci for early detection of hyperactivity
Impact publications. See above section
 
Description A genome scan for quantitive loci for early hyperactivity 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution A collaboration to examine the genome scan in order to identify the loci for early detection of hyperactivity
Impact publications. See above section
 
Description A longitudinal follow up study of autism spectrum disorders 
Organisation Nuffield Foundation
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution This study follows a group of high functioning individuals with autism into middle adult life in order to determine how these individuals are managing at this point in their lives. In addition, their siblings are being assessed in order to determine how individuals with the broader autism phenotype adjust and function in adult life and whether or not their offspring are at any increased risk for autism spectrum disorders.
Impact The project will further our understanding of the ontogeny of autism spectrum disorder and the broader autism phenotype into adult life and the architecture of the familial liability to autism. The work is based on follow up of samples that were originally studied by MRC-funded research.
Start Year 2007
 
Description A quantitative and molecular genetic study of psychological processes as mediators of genetic effects on hyperactivity 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution The main aim of this project was to use a twin design to identify cognitive-energetic processes that mediate genetic influences on attention deficit hyperactivity disorder (ADHD) symptoms in a general population sample. We completed individual 2.5-hour assessments, carried out in testing rooms at the Centre, on 672 twin pairs (1,344 children). In initial analyses we (1) established test-retest reliability for the cognitive variables, (2) demonstrated a moderate degree of genetic influences for several measures of reaction time (RT), inhibition and working memory performance, and (3) investigated methodological issues, showing for example how psychometric properties (reliability, ceiling effects) of the measures influenced the heritability estimates and how by creating composite measures we could increase reliability and heritability. Key phenotypic analyses indicated an association between ADHD symptom scores and, in particular, high RT variability (RTV), slow mean RT, poor inhibition and choice impulsivity. Further, we showed how some aspects of cognitive performance in ADHD can be modulated by motivational or energetic factors: for example, RTV normalised in a high-ADHD symptoms group in a condition with a faster presentation rate of stimuli and rewards. For choice impulsivity and delay aversion, we showed associations that were gender-specific and specific to inattentiveness rather than hyperactivity-impulsivity. Multivariate model fitting analyses indicated both shared and unique etiological pathways. For example, the shared genetic influences on ADHD symptom scores and RTV were largely also shared with those on MRT, whereas these were largely independent of the genetic influences ADHD symptom scores share with IQ. Molecular genetic analyses indicated, for example, an association between hyperactivity-impulsivity and the dopamine transporter, and between inattentiveness and the dopamine D4 receptor genes. Our further analyses suggested that, in middle childhood, symptoms of hyperactivity-impulsivity and oppositional behaviour may represent the same underlying liability, whereas the inattentive domain is more distinct. We additionally measured activity level mechanically with actigraphs and identified a common underlying activity level factor, based on both actigraph and behavioural ratings data, which was highly heritable (92%).
Impact The project forwarded the Centre's aims by refining the cognitive endophenotype for ADHD using a general population sample, refining theory and refining the association between the two ADHD symptom domains. The focus on a continuous dimension of ADHD symptoms matches the Centre's aims and complements our other research on ADHD, where we have focused on clinical diagnoses. This project was made possible by the collaborative interdisciplinary opportunities at the Centre. First, given the combined expertise of Kuntsi, Asherson and Rijsdijk, we were able to incorporate cognitive, quantitative genetic and molecular genetic strategies. Second, the recruitment of the sample from the larger 'TEDS' cohort was made possible by collaboration with Plomin. The project has contributed to the training of students on the Centre 1+3 PhD programme, as students supervised by Kuntsi, Asherson and Rijsdijk have been able to analyse data from the project.
 
Description A study of Genetics of Mathematical Cognition and Disabilities (Plomin) 
Organisation Goldsmiths, University of London
Department Department of Psychology
Country United Kingdom 
Sector Academic/University 
PI Contribution Co-investigators on an NIH grant that was renewed in 2008 to conduct in-home testing of domain-general and maths-specific cognitive skills underpinning psychometric maths ability and disability for 500 TEDS families with children selected for domain-general (low maths + low reading) and maths-specific (low maths + normal reading) problems, which will provide interesting comparisons with the web-based data that we plan to collect as part of our MRC programme grant research at age 16.
Collaborator Contribution Collaborator is principal investigator on this grant.Analysis and assistance in writing papers based on the quantitative data.
Impact Although no publications have yet been forthcoming from the renewal funded in 2008, the previous grant was responsible for several collaborative publications: 'Scant evidence for Spearman?EUR(TM)s law of diminishing returns in middle childhood'; PMID18360741; PMID19634033; PMID19732386; PMID17983460; PMID19470122; 'The ABCs of math: A genetic analysis of mathematics and its links with reading ability and general cognitive ability'; 'A twin study into the genetic and environmental influences on academ
 
Description A study of Genetics of Mathematical Cognition and Disabilities (Plomin) 
Organisation Ohio State University
Country United States 
Sector Academic/University 
PI Contribution Co-investigators on an NIH grant that was renewed in 2008 to conduct in-home testing of domain-general and maths-specific cognitive skills underpinning psychometric maths ability and disability for 500 TEDS families with children selected for domain-general (low maths + low reading) and maths-specific (low maths + normal reading) problems, which will provide interesting comparisons with the web-based data that we plan to collect as part of our MRC programme grant research at age 16.
Collaborator Contribution Collaborator is principal investigator on this grant.Analysis and assistance in writing papers based on the quantitative data.
Impact Although no publications have yet been forthcoming from the renewal funded in 2008, the previous grant was responsible for several collaborative publications: 'Scant evidence for Spearman?EUR(TM)s law of diminishing returns in middle childhood'; PMID18360741; PMID19634033; PMID19732386; PMID17983460; PMID19470122; 'The ABCs of math: A genetic analysis of mathematics and its links with reading ability and general cognitive ability'; 'A twin study into the genetic and environmental influences on academ
 
Description A three-year case control study to identify genes associated with susceptibility to bipolar depression (BaCCs) 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution This is a case-control collection 500 cases of bipolar disorder of white European ethnic origin and 500 ethnically matched healthy, screen controls. The DNA of the cases contributed to the Wellcome trust Case control Consortium (final total of 2000 cases) and the core phenotyping methodology used throughout the Wellcome Trust Case Control Consortium study was the one devised by Farmer and McGuffin (the OPCRIT system).
Impact In addition to the landmark June 2007 "seven common disorders" Nature paper many other high profile publications have resulted. We have also published several candidate-gene association study papers based on this collection. The series, one of the largest intensely phenotyped studies of bipolar disorder, has also allowed a number of interesting add-on studies looking at environmental stressors in collaboration with Sahakian's group at Cambridge.
 
Description ACTION 
Organisation Diagenode
Country Belgium 
Sector Private 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation Erasmus University Medical Center
Country Netherlands 
Sector Academic/University 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation Free University of Amsterdam
Department VU Foundation
Country Netherlands 
Sector Charity/Non Profit 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation Good Biomarker Sciences
Country Netherlands 
Sector Private 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation Karolinska Institute
Country Sweden 
Sector Academic/University 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation Leiden University
Country Netherlands 
Sector Academic/University 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation Leiden University Medical Center
Country Netherlands 
Sector Multiple 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation University of Cagliari
Country Italy 
Sector Academic/University 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation University of Helsinki
Department Department of Virology
Country Finland 
Sector Academic/University 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation University of Notre Dame
Country United States 
Sector Academic/University 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description ACTION 
Organisation University of Queensland
Department Queensland Institute of Medical Research
Country Australia 
Sector Academic/University 
PI Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Collaborator Contribution ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.
Impact Ayorech, Z., Selzam, S., Smith-Woolley, E., Knopik, V. S., Neiderhiser, J. M., DeFries, J. C., & Plomin, R. (2016). Publication Trends Over 55 Years of Behavioral Genetic Research. Behavior Genetics, 46, 603-607. doi:10.1007/s10519-016-9786-2. PMC5206393. Ayorech, Z., von Stumm, S., Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2017). Personalized media: A genetically sensitive investigation of individual differences in online media use. PLoS ONE, 12, e0168895. doi:10.1371/journal.pone.0168895. . PMC5256859. Lewis, G. J., Asbury, K., & Plomin, R. (2016). Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons. Journal of Child Psychology and Psychiatry, 58, 292-304. doi:10.1111/jcpp.12655 Porsch, R. M., Middeldorp, C. M., Cherny, S. S., Krapohl, E., van Beijsterveldt, C. E., Loukola, A., Korhonen, T., Pulkkinen, L., Corley, R., et al. (2016). Longitudinal heritability of childhood aggression. Am J Med Genet B Neuropsychiatr Genet, 171, 697-707. doi:10.1002/ajmg.b.32420 Selzam, S., Kraphol, E., von Stumm, S., O'Reilly, P., Rimfeld, K., Kovas, Y., Dale, P. S., Lee, J., & Plomin, R. (2016). Predicting Educational Achievement from DNA. Molecular Psychiatry, 22, 267-272. doi:10.1038/mp.2016.107. PMC5285461. Shakeshaft, N. G., Rimfeld, K., Schofield, K. L., Selzam, S., Malanchini, M., Rodic, M., Kovas, Y., & Plomin, R. (2016). Rotation is visualisation, 3D is 2D: using a novel measure to investigate the genetics of spatial ability. Scientific Reports, 6, 30545. doi:10.1038/srep30545. PMC4967849. Zabaneh, D., Krapohl, E., Simpson, M. A., Miller, M. B., Iacono, W. G., McGue, M., Putallaz, M., Lubinski, D., Plomin, R., et al. (2017). Fine mapping genetic associations between the HLA region and extremely high intelligence. Scientific Reports, 7, 41182. doi:10.1038/srep41182. PMC5259706.
Start Year 2014
 
Description AGRESSOTYPE: Aggression subtyping for improved insight and treatment innovation in paediatric psychiatric disorders (Kuntsi) 
Organisation Radboud University Nijmegen
Country Netherlands 
Sector Academic/University 
PI Contribution Kuntsi is listed as a Coinvestigator on a research collaboration across several European sites, headed by Professor Barbara Franke from Nijmegen, The Netherlands for a total value of EUR6000000.00 across all the sites
Collaborator Contribution All sites run research projects that are part of this collaborative effort.
Impact None yet, only started as of Nov 2013
Start Year 2013
 
Description ALSPAC collaboration (Plomin) 
Organisation University of Bristol
Department Centre for Multilevel Modelling (CMM)
Country United Kingdom 
Sector Academic/University 
PI Contribution The aim of this study is to perform a meta-analysis of GWAS results on gender role behaviour in young children as assessed by male, female and overall gender Pre-School Activities Inventories (PSAI) scores.
Collaborator Contribution The study uses data from the ALSPAC study.
Impact None as yet, this is a recent collaboration
Start Year 2010
 
Description Access to services, ADHD management and impairment from the perspective of adult with ADHD (Asherson) 
Organisation University College London
Department School of Pharmacy
Country United Kingdom 
Sector Academic/University 
PI Contribution Professor P. Asherson, here at the MRC SGDP Centre, is co-investigator on this project. He obtained funding from SHIRE, initiated collaboration and proposed the key research questions. He is involved in all steps of the study including recruitment, and review of study questions and study progress.
Collaborator Contribution Colloaboration on this project with Prof. Ian Wong, Professor of Paediatric Medicines Research and Director of Centre for Paediatric Pharmacy Research.
Impact Investigation will start January 2011. This study will delineate the reasons why patients with ADHD choose to remain on medication or to stop medication as they grow older; or the reasons for seeking the diagnosis and treatment for ADHD as adults.
Start Year 2010
 
Description Addiction Research Cluster (B Maughan) 
Organisation University of Bristol
Department School of Social and Community Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Drafting initial Cluster application; currently contributing to drafting grant application
Impact Award of Addiction Research Cluster
Start Year 2009
 
Description Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model 
Organisation King's College London
Department Institute of Psychiatry, Psychology & Neuroscience
Country United Kingdom 
Sector Academic/University 
PI Contribution Project co-ordination and supervision of students; behavioural testing; data analysis
Collaborator Contribution All consummable costs covered by grants from collaborator at Psychological Medicine Dept of IoP, KCLProject co-ordination and supervision of students; behavioural testing; data analysis
Impact 1 paper published (PMID: 20041141); 1 paper in preparation; meeting presentation (poster & oral)
Start Year 2008
 
Description Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model 
Organisation Mount Sinai Hospital (USA)
Country United States 
Sector Hospitals 
PI Contribution Project co-ordination and supervision of students; behavioural testing; data analysis
Collaborator Contribution All consummable costs covered by grants from collaborator at Psychological Medicine Dept of IoP, KCLProject co-ordination and supervision of students; behavioural testing; data analysis
Impact 1 paper published (PMID: 20041141); 1 paper in preparation; meeting presentation (poster & oral)
Start Year 2008
 
Description Amber Beckley, Univ of Stockholm, Sweden, Temi Moffitt 
Organisation Stockholm University
Country Sweden 
Sector Academic/University 
PI Contribution WE PROVIDE DATA AND MENTORING
Collaborator Contribution AMBER DOES RESEARCH
Impact FOUR PAPERS, CRIMINOLOGY
Start Year 2015
 
Description Arthur Caye, Luis Rohde, Thiago Rochas, Medical School in the Federal University of Rio Grande do Sul, Temi Moffitt 
Organisation Federal University of Rio Grande do Sul
Country Brazil 
Sector Academic/University 
PI Contribution WE PROVIDED DATA FOR META-ANALYSIS
Collaborator Contribution THEY DID THE META-ANALYSIS
Impact ONE MANUSCRIPT IN REVIEW, PSYHCIATRY
Start Year 2016
 
Description Attachment Study (Plomin TEDS) 
Organisation University of Reading
Department School of Psychology and Clinical Language Science
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of access to the Twins Early Development Study sample - including contact details for the sample.
Collaborator Contribution Access to data
Impact Project still in progress, no outputs realised yet, but manuscipts in preparation and discussion
Start Year 2010
 
Description Attention Bias Modification Treatment: International Consortium - T Eley 
Organisation National Institutes of Health (NIH)
Department National Institute of Mental Health (NIMH)
Country United States 
Sector Public 
PI Contribution Dr T Eley will undertake all DNA extraction and genotyping on these samples.
Collaborator Contribution Dr T Eley will be sent DNA samples from children taking part in an intrernational trial looking at the efficacy of attention bias modification as a treatment for child anxiety. Dr T Eley will be sent DNA samples from children taking part in an intrernational trial looking at the efficacy of attention bias modification as a treatment for child anxiety.
Impact Only just started
Start Year 2011
 
Description Attention Bias Modification Treatment: International Consortium - T Eley 
Organisation Tel Aviv University
Department Psychology Department (TAU)
Country Israel 
Sector Academic/University 
PI Contribution Dr T Eley will undertake all DNA extraction and genotyping on these samples.
Collaborator Contribution Dr T Eley will be sent DNA samples from children taking part in an intrernational trial looking at the efficacy of attention bias modification as a treatment for child anxiety. Dr T Eley will be sent DNA samples from children taking part in an intrernational trial looking at the efficacy of attention bias modification as a treatment for child anxiety.
Impact Only just started
Start Year 2011
 
Description Autism Speaks grant (Plomin) 
Organisation University College London
Department Division of Psychology & Language Sciences
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaborator is a Co-Investigator on a grant that funds a study of epigenetic biomarkers of nonshared environmental influence for TEDS MZ twins discordant for autistic traits and control MZ twins. The grant provides funds to collect blood for 60 pairs of MZ twins and to run genome-wide DNA methylation arrays.
Collaborator Contribution Collaborator (from the Department of Psychological Sciences, School of Science, Birkbeck College) is a co-investigator on this grant.
Impact PMID: 20716955; PMID: 20159110; PMID: 20505345; PMID: 20010889
Start Year 2008
 
Description Behavioural analysis of Chd7-deficient mice 
Organisation King's College London
Department Dental Institute
Country United Kingdom 
Sector Academic/University 
PI Contribution Project co-ordination; behavioural testing; data analysis
Collaborator Contribution All costs covered by a grant to collaborator at the Craniofacial Development and Stem Cell Biology Dept
Impact none yet (experiments ongoing for papers to be published in 2012)
Start Year 2011
 
Description Behavioural analysis of ENU mutant Fbxl21 
Organisation MRC Harwell
Department MRC Mammalian Genetics Unit
Country United Kingdom 
Sector Public 
PI Contribution Project co-ordination and supervision of a student; behavioural testing; data analysis
Collaborator Contribution Financial approximation of all consummable costs which shall be covered by grants to collaborator at the MRC Mammalian Genetics Unit
Impact none yet (experiments ongoing for papers to be published in 2012)
Start Year 2011
 
Description Behavioural analysis of the offspring of obese mice 
Organisation King's College London
Department School of Biomedical Sciences KCL
Country United Kingdom 
Sector Academic/University 
PI Contribution Project co-ordination and supervision of a student; behavioural testing; gene expression profiling; data analysis;
Collaborator Contribution 1 paper submitted for publication; meeting presentation (poster)
Impact 1 paper submitted for publication; meeting presentation (poster)
Start Year 2010
 
Description Biomarkers (Plomin TEDS) 
Organisation King's College London
Department Institute of Psychiatry, Psychology & Neuroscience
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of access to the Twins Early Development Study sample - including contact details for the sample.
Impact No outputs or outcomes at this point
Start Year 2010
 
Description CAPICE 
Organisation Erasmus University Rotterdam
Country Netherlands 
Sector Academic/University 
PI Contribution In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology. Professor Robert Plomin: supervising and training ESRs. He will take responsibility for network-wide training in statistical genetics, specifically twin studies.
Collaborator Contribution This collaboration will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses.
Impact Pending
Start Year 2017
 
Description CAPICE 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology. Professor Robert Plomin: supervising and training ESRs. He will take responsibility for network-wide training in statistical genetics, specifically twin studies.
Collaborator Contribution This collaboration will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses.
Impact Pending
Start Year 2017
 
Description CAPICE 
Organisation Johnson & Johnson
Department Janssen-Cilag
Country Global 
Sector Private 
PI Contribution In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology. Professor Robert Plomin: supervising and training ESRs. He will take responsibility for network-wide training in statistical genetics, specifically twin studies.
Collaborator Contribution This collaboration will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses.
Impact Pending
Start Year 2017
 
Description CAPICE 
Organisation Karolinska Institute
Country Sweden 
Sector Academic/University 
PI Contribution In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology. Professor Robert Plomin: supervising and training ESRs. He will take responsibility for network-wide training in statistical genetics, specifically twin studies.
Collaborator Contribution This collaboration will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses.
Impact Pending
Start Year 2017
 
Description CAPICE 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology. Professor Robert Plomin: supervising and training ESRs. He will take responsibility for network-wide training in statistical genetics, specifically twin studies.
Collaborator Contribution This collaboration will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses.
Impact Pending
Start Year 2017
 
Description CAPICE 
Organisation University of Catania
Country Italy 
Sector Academic/University 
PI Contribution In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology. Professor Robert Plomin: supervising and training ESRs. He will take responsibility for network-wide training in statistical genetics, specifically twin studies.
Collaborator Contribution This collaboration will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses.
Impact Pending
Start Year 2017
 
Description CAPICE 
Organisation University of Gothenburg
Country Sweden 
Sector Academic/University 
PI Contribution In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology. Professor Robert Plomin: supervising and training ESRs. He will take responsibility for network-wide training in statistical genetics, specifically twin studies.
Collaborator Contribution This collaboration will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses.
Impact Pending
Start Year 2017
 
Description CAPICE 
Organisation University of Twente
Country Netherlands 
Sector Academic/University 
PI Contribution In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology. Professor Robert Plomin: supervising and training ESRs. He will take responsibility for network-wide training in statistical genetics, specifically twin studies.
Collaborator Contribution This collaboration will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses.
Impact Pending
Start Year 2017
 
Description CATSLife 
Organisation University of California
Country United States 
Sector Academic/University 
PI Contribution Will assist with the many CATSLife analyses that emerge from the extension of CAP and LTS into early adulthood. However, the primary focus of the analyses will be to replicate CATSLife results using the TEDS longitudinal dataset on 7500 pairs of twins, which includes many of the mediators and moderators assessed in CAP and LTS in emerging adulthood, although not to the upper end of the age-span in CATSLife and without as much data on physical health as in CATSLife. Attempts will also be made to conduct combined adoption/twin analyses of CATSLife, LTS and TEDS when possible. Finally, TEDS has genome wide genotype data for nearly 6000 unrelated TEDS participants, which will enable SNP-based genetic analyses of variance and covariance and polygenic score analyses  between DNA markers and measures, mediators and moderators relevant to the proposed CATSLife project. 
Collaborator Contribution The resulting Colorado Adoption/Twin Study of Lifespan behavioral development and cognitive aging (CATSLife) will be the first prospective longitudinal study of the etiologies of behavioral and cognitive changes during the transition to middle adulthood. The aims are to: conduct a genetically sensitive study of individual differences in behavioral and cognitive change at the cusp of middle adulthood, in 1600 participants studied almost yearly from birth to early adulthood; map individual differences in growth and maintenance of cognitive abilities; evaluate and trace measured physical factors and health behaviors, biochemical markers and measured genetic pathways important to sustaining cognitive performance; and track measured environmental factors that may decrease, sustain or boost cognitive performance. The CATSLife will include expanded assessment of cognitive performance, physical functioning and health behaviors, gene pathways, including measured genetic variation in lipid, synaptic plasticity and cell-signaling paths (based on chip array variants), biochemical markers (e.g., serum lipids), and environmental measures (e.g., engagement in leisure activities). We will assess etiologies of changes in physical health and cognitive functioning, and test whether associations across domains change with age due to changes in genetic variation or self-selection of environments. Measured gene pathway sets, and environmental measures, including engagement in leisure activities and neighborhood-level variables, will be evaluated as potential factors underlying dynamics of genetic variation or environmental selection. Thus, the CATSLife will provide an unparalleled opportunity to assess prospectively the etiologies of cognitive change, and test the saliency of early childhood versus proximal influences on the genesis of cognitive decline.
Impact PMC4967849
Start Year 2015
 
Description CATSLife 
Organisation University of Colorado
Country United States 
Sector Academic/University 
PI Contribution Will assist with the many CATSLife analyses that emerge from the extension of CAP and LTS into early adulthood. However, the primary focus of the analyses will be to replicate CATSLife results using the TEDS longitudinal dataset on 7500 pairs of twins, which includes many of the mediators and moderators assessed in CAP and LTS in emerging adulthood, although not to the upper end of the age-span in CATSLife and without as much data on physical health as in CATSLife. Attempts will also be made to conduct combined adoption/twin analyses of CATSLife, LTS and TEDS when possible. Finally, TEDS has genome wide genotype data for nearly 6000 unrelated TEDS participants, which will enable SNP-based genetic analyses of variance and covariance and polygenic score analyses  between DNA markers and measures, mediators and moderators relevant to the proposed CATSLife project. 
Collaborator Contribution The resulting Colorado Adoption/Twin Study of Lifespan behavioral development and cognitive aging (CATSLife) will be the first prospective longitudinal study of the etiologies of behavioral and cognitive changes during the transition to middle adulthood. The aims are to: conduct a genetically sensitive study of individual differences in behavioral and cognitive change at the cusp of middle adulthood, in 1600 participants studied almost yearly from birth to early adulthood; map individual differences in growth and maintenance of cognitive abilities; evaluate and trace measured physical factors and health behaviors, biochemical markers and measured genetic pathways important to sustaining cognitive performance; and track measured environmental factors that may decrease, sustain or boost cognitive performance. The CATSLife will include expanded assessment of cognitive performance, physical functioning and health behaviors, gene pathways, including measured genetic variation in lipid, synaptic plasticity and cell-signaling paths (based on chip array variants), biochemical markers (e.g., serum lipids), and environmental measures (e.g., engagement in leisure activities). We will assess etiologies of changes in physical health and cognitive functioning, and test whether associations across domains change with age due to changes in genetic variation or self-selection of environments. Measured gene pathway sets, and environmental measures, including engagement in leisure activities and neighborhood-level variables, will be evaluated as potential factors underlying dynamics of genetic variation or environmental selection. Thus, the CATSLife will provide an unparalleled opportunity to assess prospectively the etiologies of cognitive change, and test the saliency of early childhood versus proximal influences on the genesis of cognitive decline.
Impact PMC4967849
Start Year 2015
 
Description CaMKII autophosphorylation controls exploratory activity to threatening novel stimuli 
Organisation Friedrich-Alexander University Erlangen-Nuremberg
Country Germany 
Sector Academic/University 
PI Contribution Project co-ordination and supervision of a student; behavioural testing; data analysis
Collaborator Contribution Project co-ordination and supervision of a student; behavioural testing; data analysisProject co-ordination and supervision of a student; behavioural testing; data analysis; All consummable costs covered by grants to collaborator at the University of Erlangen-Nuremberg
Impact 1 paper published (PMID: 21903107)
Start Year 2011
 
Description CaMKII autophosphorylation controls exploratory activity to threatening novel stimuli 
Organisation King's College London
Department Institute of Psychiatry, Psychology & Neuroscience
Country United Kingdom 
Sector Academic/University 
PI Contribution Project co-ordination and supervision of a student; behavioural testing; data analysis
Collaborator Contribution Project co-ordination and supervision of a student; behavioural testing; data analysisProject co-ordination and supervision of a student; behavioural testing; data analysis; All consummable costs covered by grants to collaborator at the University of Erlangen-Nuremberg
Impact 1 paper published (PMID: 21903107)
Start Year 2011
 
Description Causal pathways to substance use (B Maughan) 
Organisation University of Bristol
Department School of Social and Community Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Drafting grant application, and selection/modification of measures. Data collection is currently underway; once completed, my team will be involved in analysis and preparation of reports
Impact MRC grant G0800612
Start Year 2008
 
Description Centre Depression Network (DeNt) study of affected sib pairs (lead site) 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution A fundamental MRC SGDP Centre resource of affected sib pairs with depression. (This was contribution was made in 2000 - 2005, when GlaxoSmithKline was still Glaxo Wellcome R&D)
Impact This network succeeded in collecting around 1000 affected sib pairs using standardised clinical methods where the clinical fieldworkers were all trained by Anne Farmer and achieved good levels of interrater reliability. It formed the basis for the linkage studies described above as well as contributing to the association studies currently underway. It has also provide the basis for a number of interesting phenotypic studies looking at sibling pair similarities and a study of the familiality of
 
Description Change in sexual dysfunction on switching from another antipsychotic to aripiprazole 
Organisation Bristol-Myers Squibb
Country United States 
Sector Private 
PI Contribution The main hypothesis of the grant was that in patients refractory or intolerant of their current antipsychotic, that switching to aripipazole would result in a reduction in sexual dysfunction. This hypothesis was upheld. In addition, by the inclusion of patients with a range of psychotic illnesses, we discovered that the aripiprazole (often in combination with other psychotropic medications) was effective in the treatment of psychotic depression. This has since led to expansion of the licence
Impact It was discovered that the aripiprazole (often in combination with other psychotropic medications) was effective in the treatment of psychotic depression. It led to expansion of the licence for aripiprazole in the United States of America.
 
Description Child Intelligence Consortium (CHIC) - Plomin 
Organisation Children's Hospital of Philadelphia
Department Center for Applied Genomics
Country United States 
Sector Academic/University 
PI Contribution Robert Plomin established a Childhood Intelligence Consortium (CHIC) to pool in order to pool his genome-wide association (GWA) data on the Twins Early Development Study (TEDS) with data from ALSPAC (George Davey-Smith) and several other smaller studies with GWA data and cognitive data.
Collaborator Contribution Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborator leads the Statistical Genetics Committee. Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.
Impact No outputs or outcomes have been produced as yet.
Start Year 2009
 
Description Child Intelligence Consortium (CHIC) - Plomin 
Organisation Duke University Medical Centre
Department Department of Molecular Genetics
Country United States 
Sector Academic/University 
PI Contribution Robert Plomin established a Childhood Intelligence Consortium (CHIC) to pool in order to pool his genome-wide association (GWA) data on the Twins Early Development Study (TEDS) with data from ALSPAC (George Davey-Smith) and several other smaller studies with GWA data and cognitive data.
Collaborator Contribution Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborator leads the Statistical Genetics Committee. Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.
Impact No outputs or outcomes have been produced as yet.
Start Year 2009
 
Description Child Intelligence Consortium (CHIC) - Plomin 
Organisation Imperial College London
Department Faculty of Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Robert Plomin established a Childhood Intelligence Consortium (CHIC) to pool in order to pool his genome-wide association (GWA) data on the Twins Early Development Study (TEDS) with data from ALSPAC (George Davey-Smith) and several other smaller studies with GWA data and cognitive data.
Collaborator Contribution Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborator leads the Statistical Genetics Committee. Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.
Impact No outputs or outcomes have been produced as yet.
Start Year 2009
 
Description Child Intelligence Consortium (CHIC) - Plomin 
Organisation National University of Singapore
Department Department of Community, Occupational and Family Medicine
Country Singapore 
Sector Academic/University 
PI Contribution Robert Plomin established a Childhood Intelligence Consortium (CHIC) to pool in order to pool his genome-wide association (GWA) data on the Twins Early Development Study (TEDS) with data from ALSPAC (George Davey-Smith) and several other smaller studies with GWA data and cognitive data.
Collaborator Contribution Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborator leads the Statistical Genetics Committee. Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.
Impact No outputs or outcomes have been produced as yet.
Start Year 2009
 
Description Child Intelligence Consortium (CHIC) - Plomin 
Organisation University of Bristol
Department School of Social and Community Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Robert Plomin established a Childhood Intelligence Consortium (CHIC) to pool in order to pool his genome-wide association (GWA) data on the Twins Early Development Study (TEDS) with data from ALSPAC (George Davey-Smith) and several other smaller studies with GWA data and cognitive data.
Collaborator Contribution Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborator leads the Statistical Genetics Committee. Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.
Impact No outputs or outcomes have been produced as yet.
Start Year 2009
 
Description Child Intelligence Consortium (CHIC) - Plomin 
Organisation University of Edinburgh
Department Psychology
Country United Kingdom 
Sector Academic/University 
PI Contribution Robert Plomin established a Childhood Intelligence Consortium (CHIC) to pool in order to pool his genome-wide association (GWA) data on the Twins Early Development Study (TEDS) with data from ALSPAC (George Davey-Smith) and several other smaller studies with GWA data and cognitive data.
Collaborator Contribution Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborator leads the Statistical Genetics Committee. Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.
Impact No outputs or outcomes have been produced as yet.
Start Year 2009
 
Description Child Intelligence Consortium (CHIC) - Plomin 
Organisation University of Queensland
Department Queensland Institute of Medical Research
Country Australia 
Sector Academic/University 
PI Contribution Robert Plomin established a Childhood Intelligence Consortium (CHIC) to pool in order to pool his genome-wide association (GWA) data on the Twins Early Development Study (TEDS) with data from ALSPAC (George Davey-Smith) and several other smaller studies with GWA data and cognitive data.
Collaborator Contribution Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborator leads the Statistical Genetics Committee. Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.
Impact No outputs or outcomes have been produced as yet.
Start Year 2009
 
Description Child Intelligence Consortium (CHIC) - Plomin 
Organisation University of Western Australia
Department Centre for Genetic Epidemiology
Country Australia 
Sector Academic/University 
PI Contribution Robert Plomin established a Childhood Intelligence Consortium (CHIC) to pool in order to pool his genome-wide association (GWA) data on the Twins Early Development Study (TEDS) with data from ALSPAC (George Davey-Smith) and several other smaller studies with GWA data and cognitive data.
Collaborator Contribution Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborator leads the Statistical Genetics Committee. Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.Collaborating group will provide genome-wide association results for IQ scores.
Impact No outputs or outcomes have been produced as yet.
Start Year 2009
 
Description Collaboration with Dr Schafer - H Fisher 
Organisation University Medical Center Hamburg-Eppendorf
Country Germany 
Sector Hospitals 
PI Contribution Dr Schafer from the University Medical Center Hamburg-Eppendorf, Germany was hosted at the IOP by Dr Helen Fisher for 2 months in 2010. This led to publications and further collaborations, including an invite for a talk in Hamburg in 2012
Collaborator Contribution Dr Schafer has invited Dr Fisher to Germany for a talk in Hamburg
Impact 6 papers published to date. Dr Schafer also invited Dr Fisher to give a talk in Hamburg in 2012.
Start Year 2010
 
Description Collaboration with Marco Battaglia 
Organisation San Raffaele Hospital
Department San Raffaele Scientific Institute (SRSI)
Country Italy 
Sector Academic/University 
PI Contribution Contributed conceptual and analytic expertise, to collaborate on novel analysis of relevant twin data from an Italian population sample.
Collaborator Contribution Collaborated on a recent paper exploring the phenotypic and genetic association between clumsiness and autistic-like traits. Pooled expertise in twin-modelling and theoretical perspectives, with this Italian team, bringing new twin data to bear on questions of shared interest
Impact Published paper: Moruzzi S, Ogliari A, Ronald A, Happ? F, Battaglia M. The nature of covariation between autistic traits and clumsiness: a twin study in a general population sample. J Autism Dev Disord. 2011 Dec;41(12):1665-74. PubMed PMID: 21347613.
Start Year 2009
 
Description Collaborative program with Shanghai - Breen and McGuffin 
Organisation Shanghai Jiao Tong University
Country China 
Sector Academic/University 
PI Contribution Dr Gerome Breen and Prof Peter McGuffin chair a collabroative program, fundied in part through an FP7 Marie Curie Staff Exchange program.
Collaborator Contribution Prof Lin He at the Shanghai University is also collaborating on this Marie Curie Staff Exchange program.
Impact Ongoing work
Start Year 2012
 
Description Colombo Twin and Singleton Study (CoTaSS) follow up study - F Rijsdijk 
Organisation Institute of Development Research (IRD)
Country France 
Sector Public 
PI Contribution Investigating the overlap between metabolic syndrome and depression in a Sri Lankan population of twins and singletons.
Collaborator Contribution Data collection will include questionnaire, anthropometric and biological measures as well as electrophysiological data. This project is an example of a collacboration between the Centre and a Middle-Income country. The project takes advantage of the expertise in statistical genetics at the Centre.
Impact The research is an example of how mulitple approaches (e.g. twin modelling, biomarkers and electrophysiology) can be used to help elucidate the aetiology of mental and physical health problems and the relationship between them.
Start Year 2011
 
Description Colombo Twin and Singleton Study (CoTaSS) follow up study - F Rijsdijk 
Organisation King's College London
Department Department of Psychological Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Investigating the overlap between metabolic syndrome and depression in a Sri Lankan population of twins and singletons.
Collaborator Contribution Data collection will include questionnaire, anthropometric and biological measures as well as electrophysiological data. This project is an example of a collacboration between the Centre and a Middle-Income country. The project takes advantage of the expertise in statistical genetics at the Centre.
Impact The research is an example of how mulitple approaches (e.g. twin modelling, biomarkers and electrophysiology) can be used to help elucidate the aetiology of mental and physical health problems and the relationship between them.
Start Year 2011
 
Description Colombo Twin and Singleton Study (CoTaSS) follow up study - F Rijsdijk 
Organisation University of Sydney
Country Australia 
Sector Academic/University 
PI Contribution Investigating the overlap between metabolic syndrome and depression in a Sri Lankan population of twins and singletons.
Collaborator Contribution Data collection will include questionnaire, anthropometric and biological measures as well as electrophysiological data. This project is an example of a collacboration between the Centre and a Middle-Income country. The project takes advantage of the expertise in statistical genetics at the Centre.
Impact The research is an example of how mulitple approaches (e.g. twin modelling, biomarkers and electrophysiology) can be used to help elucidate the aetiology of mental and physical health problems and the relationship between them.
Start Year 2011
 
Description Consortium on the Genetics of High Cognitive (GHCA) - Plomin 
Organisation Ohio State University
Country United States 
Sector Academic/University 
PI Contribution Cognitive ability data obtained from TEDS will be used in this study.
Collaborator Contribution Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive ability abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a
Impact The following publications have arisen from this study so far: PMID19488046; PMID19381794; PMID19247827; PMID: 19430899; PMID: 19424784; PMID: 19288254; PMID: 19377873; PMID: 19377874; PMID: 19418212; PMID: 19296213; PMID: 19377870.
Start Year 2008
 
Description Consortium on the Genetics of High Cognitive (GHCA) - Plomin 
Organisation University of Amsterdam
Country Netherlands 
Sector Academic/University 
PI Contribution Cognitive ability data obtained from TEDS will be used in this study.
Collaborator Contribution Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive ability abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a
Impact The following publications have arisen from this study so far: PMID19488046; PMID19381794; PMID19247827; PMID: 19430899; PMID: 19424784; PMID: 19288254; PMID: 19377873; PMID: 19377874; PMID: 19418212; PMID: 19296213; PMID: 19377870.
Start Year 2008
 
Description Consortium on the Genetics of High Cognitive (GHCA) - Plomin 
Organisation University of Colorado Boulder
Country United States 
Sector Academic/University 
PI Contribution Cognitive ability data obtained from TEDS will be used in this study.
Collaborator Contribution Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive ability abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a
Impact The following publications have arisen from this study so far: PMID19488046; PMID19381794; PMID19247827; PMID: 19430899; PMID: 19424784; PMID: 19288254; PMID: 19377873; PMID: 19377874; PMID: 19418212; PMID: 19296213; PMID: 19377870.
Start Year 2008
 
Description Consortium on the Genetics of High Cognitive (GHCA) - Plomin 
Organisation University of Minnesota
Country United States 
Sector Academic/University 
PI Contribution Cognitive ability data obtained from TEDS will be used in this study.
Collaborator Contribution Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive ability abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a
Impact The following publications have arisen from this study so far: PMID19488046; PMID19381794; PMID19247827; PMID: 19430899; PMID: 19424784; PMID: 19288254; PMID: 19377873; PMID: 19377874; PMID: 19418212; PMID: 19296213; PMID: 19377870.
Start Year 2008
 
Description Consortium on the Genetics of High Cognitive (GHCA) - Plomin 
Organisation University of Queensland
Department School of Psychology
Country Australia 
Sector Academic/University 
PI Contribution Cognitive ability data obtained from TEDS will be used in this study.
Collaborator Contribution Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive ability abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a
Impact The following publications have arisen from this study so far: PMID19488046; PMID19381794; PMID19247827; PMID: 19430899; PMID: 19424784; PMID: 19288254; PMID: 19377873; PMID: 19377874; PMID: 19418212; PMID: 19296213; PMID: 19377870.
Start Year 2008
 
Description Consortium on the Genetics of High Cognitive (GHCA) - Plomin 
Organisation Vanderbilt University
Country United States 
Sector Academic/University 
PI Contribution Cognitive ability data obtained from TEDS will be used in this study.
Collaborator Contribution Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a GHCA member and is an expert on the genetics of cognitive ability abilitites and has obtained cognitive ability data that will be used in the study.Collaborator is a
Impact The following publications have arisen from this study so far: PMID19488046; PMID19381794; PMID19247827; PMID: 19430899; PMID: 19424784; PMID: 19288254; PMID: 19377873; PMID: 19377874; PMID: 19418212; PMID: 19296213; PMID: 19377870.
Start Year 2008
 
Description De novo epigenetic changes and paternal age in schizophrenia 
Organisation British Medical Association (BMA)
Country United Kingdom 
Sector Learned Society 
PI Contribution Studying epigenetic changes occurring in sperm and subsequently transmitted to offspring may have widespread use in Centre research
Impact Newly awarded grant. Research still being conducted
Start Year 2008
 
Description Depression at 17: ALSPAC (B Maughan) 
Organisation University of Bristol
Department Faculty of Medicine and Dentistry
Country United Kingdom 
Sector Academic/University 
PI Contribution Drafting grant application and selection of measures. Data collection is now underway; once completed, my team will be involved in data analysis and preparation of publications
Impact Wellcome Trust grant WT084268MA
Start Year 2008
 
Description Development of training schemes with University of Kyushu - E Taylor 
Organisation Kyushu University
Country Japan 
Sector Academic/University 
PI Contribution GUidance in the development of training schemes
Collaborator Contribution Prof E Taylor will collaborate with Professor Keiko Yoshido at the University of Kyushu, for development of training schemes. Financial contributions will be discussed and arranged in the future
Impact The schemes for training will be developed over the next few years, in collaboration with Kyushi University
Start Year 2010
 
Description Developmental Pathways to Physical Health Among Young People: A Cumulative Adversity and Advantage During the First 26 Years of Life 
Organisation William T. Grant Foundation
Country United States 
Sector Charity/Non Profit 
PI Contribution The programme underscores the importance of longitudinal research to understanding the enduring influence of childhood conditions on adult health and helps to identify important opportunities or intervention in early development in order to promote adult health.
Impact This programme of research discovered that childhood stress has enduring effects on adult immune functioning.
 
Description Diagnostic rates and treatment outcome study of ADHD (Asherson) 
Organisation University of St Andrews
Department School of Medicine St Andrews
Country United Kingdom 
Sector Academic/University 
PI Contribution The collaboration with the Clinical team at St Andrews will examine diagnostic rates and treatment outcome study of ADHD in the St Andrews secure unit. This research is funded by St Andrews Healthcare and Asherson and Young lead all aspects of the study.
Collaborator Contribution Collaboration with Dr Suzy Young and clinical team at St Andrews on all aspects of the study
Impact This study will establish rates of ADHD within secure unit patients at St Andrews; and the link between ADHD and behavioural problems within the unit. The second stage of the study will investigate the impact of treatment on behavioural problems and levels symptoms and impairments within high risk patients with severe behavioural problems
Start Year 2010
 
Description Dorret Boomsma, Free University of Amsterdam, Temi Moffitt 
Organisation Free University of Amsterdam
Country Netherlands 
Sector Academic/University 
PI Contribution WE EXCHANGE GENETIC DATA for GWAS and EWAS analyses
Collaborator Contribution EXCHANGE OF STAFF EXPERTISE AND IDEAS
Impact MULTIPLE-COHORT PAPERS IN DRAFT FORM TO BE SUBMITTED FOR REVIEW, PSYCHOLOGY
Start Year 2017
 
Description Dr Eley - International Study of Genetic Factors in Exposure Treatments of Anxiety Disorders 
Organisation Ruhr University Bochum
Department Faculty of Psychology
Country Germany 
Sector Academic/University 
PI Contribution Dr Eley is leading the genetic aspects of this project. All DNA samples will be sent to her and all genotyping and RNA analysis will be done within her group based at the MRC SGDP Centre.
Collaborator Contribution The Ruhr University department are conducting a large study of exposure therapy in adults with phobias and have asked me to lead the genetic component of the project. Dr Eley will therefore have DNA on psychological treatment response, and funding to genotype, from a large sample of adults which can complement the child sample being obtained within this grant.
Impact They are just beginning to obtain DNA samples now.
Start Year 2010
 
Description Dunedin Multidisciplinary Health and Development Study, Univ of Otago, New Zealand 
Organisation University of Otago
Country New Zealand 
Sector Academic/University 
PI Contribution MRC grant, research protocol
Collaborator Contribution Manage sample, collect data
Impact This is multidisciplinary. 1300+ publications have been produced.
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation Cardiff University
Department Division of Psychological Medicine and Clinical Neurosciences
Country United Kingdom 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation Hungarian Academy of Sciences (MTA)
Country Hungary 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation Karolinska Institute
Department Department of Biosciences and Nutrition
Country Sweden 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation Maastricht University (UM)
Department Faculty of Psychology and Neuroscience
Country Netherlands 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation Maastricht University (UM)
Country Netherlands 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation National Center for Scientific Research (Centre National de la Recherche Scientifique CNRS)
Department Laboratory of Cognitive Sciences and Psycholinguistics CNRS
Country France 
Sector Public 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation National Institute of Health and Medical Research (INSERM)
Country France 
Sector Public 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation Philipp University of Marburg
Department Department of Neurology
Country Germany 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation University of Bonn
Department Institute of Human Genetics, Life and Brain Center
Country Germany 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation University of Jyvaskyla
Country Finland 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation University of Oxford
Department Department of Physiology, Anatomy and Genetics
Country United Kingdom 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation University of Oxford
Department Department of Statistics
Country United Kingdom 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation University of Salzburg
Department Psychology Salzburg
Country Austria 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description Dyslexia genes and neurobiological pathways (Plomin) 
Organisation University of Zurich
Department Department of Child and Adolescent Psychiatry (KJPD)
Country Switzerland 
Sector Academic/University 
PI Contribution Our workpackage has contributed quantitative genetic research and provides a large replication sample for molecular genetic analyses that arise from NeuroDys. The molecular genetic research is ongoing using Affymetrix 6.0 GeneChip data to replicate current and future molecular genetics results that emerge from NeuroDys in our Twins Early Development Study (TEDS) which has extensive data on family and school environments as well as on reading and related academic skills and behavior problems. We have also published the first genome-wide association analysis of reading as a quantitative trait (Meaburn et al., 2008). Our quantitative genetic research has included structural equation modeling analyses of longitudinal data on reading performance and environmental risk factors for reading disabilities (both family-based factors, such as shared book reading, and school-based factors, such as child-teacher relationship).
Collaborator Contribution Collaborator is principal investigator on project. Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project Collaborator is co-investigator on projectCollaborator is co-investigator on projectCollaborator is co-investigator on project Collaborator is co-investigator on project
Impact This work has resulted in six empirical publications (see outputs).PMID: 17328696; PMID: 18093024; PMID: 20383260; PMID: 17995572; PMID: 17714376; PMID: 18506044; PMID: 17684495.
Start Year 2006
 
Description ENIGMA: Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA), ADHD Neuroimaging Meta-Analysis Working Group (Kuntsi) 
Organisation Radboud University Nijmegen
Country Netherlands 
Sector Academic/University 
PI Contribution Kuntsi is listed as one of the PIs, and the PI of the fMRI dataset that contributes to these analyses (the data collection for which was funded by my MRC grant).
Collaborator Contribution Multiple sites contribute datasets and participate in the analyses and write up of papers.
Impact None yet, only started very recently
Start Year 2013