An RCT of warfarin versus aspirin for atrial fibrillation in an elderly (aged over 74) primary care population

Lead Research Organisation: University of Birmingham
Department Name: Health and Population Sciences

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

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Apenteng PN (2017) Incidence of venous thromboembolism in care homes: a prospective cohort study. in The British journal of general practice : the journal of the Royal College of General Practitioners

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Camm AJ (2015) Non-vitamin K antagonist oral anticoagulants and atrial fibrillation guidelines in practice: barriers to and strategies for optimal implementation. in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

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Davis RC (2012) Prevalence of atrial fibrillation in the general population and in high-risk groups: the ECHOES study. in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

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Echocardiographic Normal Ranges Meta-Analysis Of The Left Heart Collaboration (2015) Ethnic-Specific Normative Reference Values for Echocardiographic LA and LV Size, LV Mass, and Systolic Function: The EchoNoRMAL Study. in JACC. Cardiovascular imaging

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Fitzmaurice DA (2014) Research into practice: management of atrial fibrillation in general practice. in The British journal of general practice : the journal of the Royal College of General Practitioners

 
Description Citations
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in clinical reviews
Impact hjopefully informed clinical practice
 
Guideline Title American and European AF Guidelines
Description Guidelines
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in clinical guidelines
Impact Changed guidelines
 
Description AF Screening: How long and how often should people be screened to see if they do have paroxysmal AF?
Amount £400,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 06/2018 
End 09/2019
 
Description NIHR Stroke Prevention Programme RP-PG-0606-1153
Amount £2,000,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 01/2007 
End 01/2015
 
Description Reference Number: RP-PG-0217-20007 Programme Title: Screening for Atrial Fibrillation
Amount £2,500,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 01/2018 
End 12/2022
 
Description AF Screening Trial Programme 
Organisation Cambridge Insitu
Country United Kingdom 
Sector Private 
PI Contribution Cambridge (Mant J) and Oxford (Hobbs F, McManus R) collaboration own a successful NIHR Programme grant to commence in 2018
Collaborator Contribution Co-investigators
Impact None yet
Start Year 2018
 
Description European Stroke prevention Programme 
Organisation European Union
Country European Union (EU) 
Sector Public 
PI Contribution Supported European Stroke Society in developing clinical and public policy guidance documents
Collaborator Contribution see above
Impact M
Start Year 2017
 
Description Primary Care Stroke Prevention Programme 
Organisation University of Cambridge
Department Department of Public Health and Primary Care
Country United Kingdom 
Sector Academic/University 
PI Contribution Ongoing links with Prof Jonathan Mant, University of Cambridge over new trials and studies
Collaborator Contribution Design and delivery
Impact Fletcher K, Mant J, McManus R, Campbell S, Betts J, Taylor C, Virdee S, Jowett S, Martin U, Greenfield S, Ford G, Freemantle N, Hobbs FD. Protocol for Past BP: a randomised controlled trial of different blood pressure targets for people with a history of stroke of transient ischaemic attack (TIA) in primary care. BMC Cardiovasc Disord. 2010; 10: 37 Fletcher K, Mant J, McManus R, Campbell S, Betts J, Taylor C, Virdee S, Jowett S, Martin U, Greenfield S, Ford G, Freemantle N, Hobbs FD. Protocol for Past BP: a randomised controlled trial of different blood pressure targets for people with a history of stroke of transient ischaemic attack (TIA) in primary care. BMC Cardiovasc Disord. 2010 Aug 9;10:37.
Start Year 2008
 
Description Society Guideline Working Group 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Review of SPAF guidelines

NICE recommended changes and new LES policy for AF management in primary care.
Year(s) Of Engagement Activity 2009,2016