Establishment of a Resource for Long-Term Study of Hepatitis C Virus Infection in the UK - HCV Research UK
Lead Research Organisation:
University of Glasgow
Department Name: UNLISTED
Abstract
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Organisations
- University of Glasgow (Lead Research Organisation)
- UNIVERSITY HOSPITALS OF MORECAMBE BAY NHS FOUNDATION TRUST (Collaboration)
- Bradford Royal Infirmary (Collaboration)
- Queen Alexandra Hospital (Collaboration)
- Manchester Royal Infirmary (Collaboration)
- NHS GRAMPIAN (Collaboration)
- Bristol Royal Infirmary (Collaboration)
- Birmingham Heartlands Hospital (Collaboration)
- OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST (Collaboration)
- AbbVie Inc (Collaboration)
- Queen Elizabeth University Hospital (Collaboration)
- Derriford Hospital (Collaboration)
- Shrewsbury and Telford Hospital NHS Trust (Collaboration)
- University College Hospital (Collaboration)
- EAST LANCASHIRE HOSPITALS NHS TRUST (Collaboration)
- FREEMAN HOSPITAL (Collaboration)
- University Hospital Lewisham (Collaboration)
- Royal Free Hospital (Collaboration)
- NHS Greater Glasgow and Clyde (NHSGGC) (Collaboration)
- Royal Derby Hospital (Collaboration)
- UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST (Collaboration)
- Gilead Sciences, Inc. (Collaboration)
- United Lincolnshire Hospitals NHS Trust (Collaboration)
- Royal Hospital for Children (Collaboration)
- Singleton Hospital (Collaboration)
- Queen Elizabeth Hospital Birmingham (Collaboration)
- Leeds Teaching Hospitals Charitable Foundation (Collaboration)
- Blackpool Victoria Hospital (Collaboration)
- Johnson & Johnson (Collaboration)
- Royal Preston Hospital (Collaboration)
- St Mary's Hospital, London (Collaboration)
- Frimley Park Hospital NHS Foundation Trust (Collaboration)
- King's College Hospital NHS Foundation Trust (NCH) (Collaboration)
- NHS Lothian (Collaboration)
- Chelsea and Westminster Hospital NHS Foundation Trust (Collaboration)
- SANDWELL AND WEST BIRMINGHAM HOSPITALS NHS TRUST (Collaboration)
- Royal Sussex County Hospital (Collaboration)
- St George's NHS Trust, London (Collaboration)
- St James's University Hospital (Jimmy's) (Collaboration)
- Birmingham Women's and Children's NHS Foundation Trust (Collaboration)
- PENNINE ACUTE HOSPITALS NHS TRUST (Collaboration)
- STOP-HCV (Collaboration)
- Ninewells Hospital (Collaboration)
- Bristol-Myers Squibb (Collaboration)
- GREAT ORMOND STREET HOSPITAL FOR CHILDREN NHS FOUNDATION TRUST (Collaboration)
- Addenbrooke's Hospital (Collaboration)
- Royal London Hospital (Collaboration)
- GlaxoSmithKline (GSK) (Collaboration)
- Monklands District General Hospital (Collaboration)
- Royal Liverpool University Hospital (Collaboration)
- Brighton and Sussex University Hospitals NHS Trust (Collaboration)
- Tayside Children’s Hospital (Collaboration)
- UNIVERSITY OF NOTTINGHAM (Collaboration)
- James Cook University Hospital (Collaboration)
- Laser Analytica (Collaboration)
- Hull Royal Infirmary (Collaboration)
- Southampton General Hospital (Collaboration)
- Queen's Medical Centre (Collaboration)
- Boehringer Ingelheim (Collaboration)
- Sheffield Teaching Hospitals NHS Foundation Trust (Collaboration)
- BUCKINGHAMSHIRE HEALTHCARE NHS TRUST (Collaboration)
People |
ORCID iD |
Publications
Cheung MCM
(2016)
Outcomes after successful direct-acting antiviral therapy for patients with chronic hepatitis C and decompensated cirrhosis.
in Journal of hepatology
Foster GR
(2016)
Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis.
in Journal of hepatology
Thomson E
(2016)
Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes.
in Journal of clinical microbiology
McLauchlan J
(2017)
Cohort Profile: The Hepatitis C Virus (HCV) Research UK Clinical Database and Biobank.
in International journal of epidemiology
Ansari MA
(2017)
Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus.
in Nature genetics
Filipe Ana Da Silva
(2017)
Response to DAA therapy in the NHS England Early Access Programme for rare HCV subtypes from low and middle income countries
in JOURNAL OF HEPATOLOGY
Da Silva Filipe A
(2017)
Response to DAA therapy in the NHS England Early Access Programme for rare HCV subtypes from low and middle income countries.
in Journal of hepatology
| Description | Gilead Clinical Trial |
| Amount | £35,000 (GBP) |
| Organisation | Gilead Sciences, Inc. |
| Department | Gilead |
| Sector | Private |
| Country | United Kingdom |
| Start | 11/2013 |
| End | 12/2014 |
| Description | HCV Research UK - Abbvie #1 |
| Amount | £30,000 (GBP) |
| Organisation | AbbVie Inc |
| Sector | Private |
| Country | United States |
| Start | 12/2014 |
| End | 12/2018 |
| Description | HCV Research UK - Abbvie #2 |
| Amount | £75,000 (GBP) |
| Organisation | AbbVie Inc |
| Sector | Private |
| Country | United States |
| Start | 02/2016 |
| End | 12/2017 |
| Description | HCV Research UK - BMS |
| Amount | £30,000 (GBP) |
| Organisation | Bristol-Myers Squibb |
| Sector | Private |
| Country | United States |
| Start | 01/2014 |
| End | 12/2018 |
| Description | HCV Research UK - BMS #2 |
| Amount | £30,000 (GBP) |
| Organisation | Bristol-Myers Squibb |
| Sector | Private |
| Country | United States |
| Start | 01/2014 |
| End | 12/2018 |
| Description | HCV Research UK - BMS (EAP) |
| Amount | £23,000 (GBP) |
| Organisation | Bristol-Myers Squibb |
| Sector | Private |
| Country | United States |
| Start | 01/2014 |
| End | 12/2018 |
| Description | HCV Research UK - BMS#3 |
| Amount | £63,000 (GBP) |
| Organisation | Bristol-Myers Squibb |
| Sector | Private |
| Country | United States |
| Start | 03/2015 |
| End | 12/2018 |
| Description | HCV Research UK - BMS#4 |
| Amount | £75,000 (GBP) |
| Organisation | Bristol-Myers Squibb |
| Sector | Private |
| Country | United States |
| Start | 11/2015 |
| End | 12/2017 |
| Description | HCV Research UK - Boehringer Ingelheim |
| Amount | £30,000 (GBP) |
| Organisation | Boehringer Ingelheim |
| Sector | Private |
| Country | Germany |
| Start | 01/2014 |
| End | 12/2018 |
| Description | HCV Research UK - GSK |
| Amount | £40,000 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 09/2013 |
| End | 12/2018 |
| Description | HCV Research UK - Gilead |
| Amount | £35,000 (GBP) |
| Organisation | Gilead Sciences, Inc. |
| Department | Gilead |
| Sector | Private |
| Country | United Kingdom |
| Start | 10/2013 |
| End | 12/2018 |
| Description | HCV Research UK - Gilead #3 |
| Amount | £43,000 (GBP) |
| Organisation | Gilead Sciences, Inc. |
| Department | Gilead |
| Sector | Private |
| Country | United Kingdom |
| Start | 02/2015 |
| End | 12/2016 |
| Description | HCV Research UK - Gilead #4 |
| Amount | £45,000 (GBP) |
| Organisation | Gilead Sciences, Inc. |
| Department | Gilead |
| Sector | Private |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 12/2018 |
| Description | HCV Research UK - Gilead #5 |
| Amount | £30,000 (GBP) |
| Organisation | Gilead Sciences, Inc. |
| Department | Gilead |
| Sector | Private |
| Country | United Kingdom |
| Start | 08/2015 |
| End | 12/2018 |
| Description | HCV Research UK - Gilead #6 |
| Amount | £15,000 (GBP) |
| Organisation | Gilead Sciences, Inc. |
| Sector | Private |
| Country | United States |
| Start | 12/2016 |
| End | 12/2019 |
| Description | HCV Research UK - Gilead (EAP) |
| Amount | £23,000 (GBP) |
| Organisation | Gilead Sciences, Inc. |
| Department | Gilead |
| Sector | Private |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 12/2018 |
| Description | HCV Research UK - Gilead (NICE) |
| Amount | £30,000 (GBP) |
| Organisation | Gilead Sciences, Inc. |
| Department | Gilead |
| Sector | Private |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 12/2018 |
| Description | HCV Research UK - Gilead (triple therapy) |
| Amount | £102,000 (GBP) |
| Organisation | Gilead Sciences, Inc. |
| Department | Gilead |
| Sector | Private |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 12/2018 |
| Description | HCV Research UK - Glasgow Caledonian University |
| Amount | £1,000 (GBP) |
| Funding ID | C0365 |
| Organisation | Glasgow Caledonian University |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 04/2020 |
| Description | HCV Research UK - Janssen |
| Amount | £15,000 (GBP) |
| Organisation | Janssen Research & Development |
| Sector | Private |
| Country | Global |
| Start | 03/2014 |
| End | 12/2018 |
| Description | HCV Research UK - Janssen (Genotype 1 & 4) |
| Amount | £37,500 (GBP) |
| Organisation | Janssen Research & Development |
| Sector | Private |
| Country | Global |
| Start | 03/2014 |
| End | 12/2018 |
| Description | HCV Research UK - Janssen Diagnostics |
| Amount | £10,000 (GBP) |
| Organisation | Janssen Research & Development |
| Sector | Private |
| Country | Global |
| Start | 01/2014 |
| End | 12/2018 |
| Description | HCV Research UK - STOP-HCV |
| Amount | £50,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2013 |
| End | 08/2018 |
| Description | HCV Research UK - University of Liverpool |
| Amount | £15,246 (GBP) |
| Funding ID | C0365 |
| Organisation | University of Liverpool |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 02/2016 |
| End | 05/2020 |
| Description | HCV Research UK - University of Plymouth |
| Amount | £2,970 (GBP) |
| Funding ID | C0365 |
| Organisation | University of Plymouth |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 04/2020 |
| Title | HCV Research UK Clinical Database and Biobank |
| Description | Information from consenting patients have been entered into a clinical database. These patients also provide clinical samples for the biobank. The clinical database and management system for the biobank are bespoke systems built specifically for HCV Research UK. They have been developed such that interaction between the two database systems can be achieved. The data and samples are made available to researchers (either in academia or the pharmaceutical industry; both UK- and non-UK-based) |
| Type Of Material | Biological samples |
| Year Produced | 2013 |
| Provided To Others? | Yes |
| Impact | The establishment of HCV Research UK has underpinned and directly enabled the following: 1. Award of £4M grant on MRC call for Stratified Medicine to the STOP-HCV consortium, a group of academic institutions, national health agencies and pharmaceutical companies. 2. Requests from several pharmaceutical companies for access to data for submissions to NICE for new anti-viral compounds. 3. Requests from pharmaceutical companies for access to samples for new diagnostic tests. 4. Access to data and samples from HCV-infected patients from across the UK for phyloepidemiological studies. 5. Provided a large number of samples for development of high throughput sequencing methodologies. 6. Provided the samples for a Health Innovation Challenge Fund award by Wellcome Trust for enabling roll-out of high throughput sequencing across NHS sites. 7. Enabled collection of data and samples on Early Access Programme, an initiative funded by NHS England to allow patients access to interferon-free therapies for HCV infection ahead of NICE approval. |
| URL | http://www.hcvresearchuk.org/ |
| Title | NGS Target Enrichment |
| Description | The technology enabled the enrichment of HCV-specific sequences in Next Generation Sequencing. It also increased the numbers of samples that could be included in a single sequencing run from about 10-12 to 90, which is much more cost effective. |
| Type Of Material | Technology assay or reagent |
| Provided To Others? | No |
| Impact | The methodology is now being developed for diagnostic services and to establish an enrichment platform for flaviviruses circulating in the Philippines. |
| Title | HCV Research UK |
| Description | HCV Research UK holds the clinical data for approximately 11,000 patients infected with hepatitis C virus in the UK. We also have a linked biobank database for holding the information on all samples processed and stored in the HCV Research UK biorepository. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2013 |
| Provided To Others? | Yes |
| Impact | The data and samples have been used for a number of purposes including: 1. Submissions to NICE by pharma companies 2. Submission to the European Medicines Agency on drug utilisation 3. Data provided, in combination with samples, for extensive viral sequencing and host genetic studies. 4. Acting as the data and sample repository for a Gilead-funded phase III clinical trial in the UK, USA and Australia (BOSON) 5 Acting as the data and sample repository for the NHS England Early Access Programme that provides IFN-free, all oral therapy to HCV-infected patients with serious liver disease. 6. Underpins the data and samples provided to the STOP-HCV MRC-funded consortium. 7. Provides infrastructure support for the STOP-HCV Cirrhosis study and the STOP-HCV1 EME study. |
| URL | http://www.hcvresearchuk.org |
| Description | Determining resistance to all-oral DAAs using in vitro systems |
| Organisation | Royal London Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | My group has provided HCV sequence data to direct the in vitro studies at the Royal London. |
| Collaborator Contribution | The Royal London has carried out the in vitro studies in the project. |
| Impact | The collaboration has given rise to oral and poster presentations at national and international conferences. |
| Start Year | 2015 |
| Description | HCV Research UK - Abbvie |
| Organisation | AbbVie Inc |
| Country | United States |
| Sector | Private |
| PI Contribution | Provision of data from the HCV Research UK database |
| Collaborator Contribution | Provision of data from the HCV Research UK database |
| Impact | Recruitment and data collectionfrom patients receiving new therapies for HCV infection. |
| Start Year | 2016 |
| Description | HCV Research UK - Aberdeen Royal Infirmary |
| Organisation | NHS Grampian |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Addenbrooke's Hospital |
| Organisation | Addenbrooke's Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - BMS |
| Organisation | Bristol-Myers Squibb |
| Country | United States |
| Sector | Private |
| PI Contribution | Provision of data from the HCV Research UK database |
| Collaborator Contribution | Financial contribution |
| Impact | N/A |
| Start Year | 2013 |
| Description | HCV Research UK - Birmingham Children's Hospital |
| Organisation | Birmingham Women's and Children's NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Blackpool Victoria Hospital |
| Organisation | Blackpool Victoria Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Boehringer Ingelheim |
| Organisation | Boehringer Ingelheim |
| Country | Germany |
| Sector | Private |
| PI Contribution | Data provision from the HCV Research UK database |
| Collaborator Contribution | Data provision form the HCV Research UK database |
| Impact | Data provided for ongoing support of HCV Research UK |
| Start Year | 2013 |
| Description | HCV Research UK - Bradford Royal Infirmary |
| Organisation | Bradford Royal Infirmary |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Bradford Royal Infirmary |
| Organisation | Bradford Royal Infirmary |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Bristol Myers Squibb |
| Organisation | Bristol-Myers Squibb |
| Country | United States |
| Sector | Private |
| PI Contribution | Provision of data to BMS from HCV Research UK |
| Collaborator Contribution | Provision of data to BMS from HCV Research UK for a real world study on outcomes of use of DAAs for HCV-infected patients |
| Impact | Presentation at EASL 2017 on outcomes from DAA Real World study. |
| Start Year | 2016 |
| Description | HCV Research UK - Bristol Royal Infirmary |
| Organisation | Bristol Royal Infirmary |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2014 |
| Description | HCV Research UK - Chelsea and Westminster, London |
| Organisation | Chelsea and Westminster Hospital NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2013 |
| Description | HCV Research UK - Derriford Hospital |
| Organisation | Derriford Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Freeman Hospital |
| Organisation | Freeman Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Frimley Park |
| Organisation | Frimley Health NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2014 |
| Description | HCV Research UK - GSK |
| Organisation | GlaxoSmithKline (GSK) |
| Country | Global |
| Sector | Private |
| PI Contribution | Storage of samples from Eltrombopag Prospective Observational Cohort Study Nested Within the HCV Research UK National Registry |
| Collaborator Contribution | Financial contribution |
| Impact | N/A |
| Start Year | 2013 |
| Description | HCV Research UK - Gartnavel General Hospital |
| Organisation | NHS Greater Glasgow and Clyde (NHSGGC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Gilead |
| Organisation | Gilead Sciences, Inc. |
| Department | Gilead |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Provision of samples from HCV Research UK Biobank |
| Collaborator Contribution | Funding for a research assistant to work in the HCV Research UK biobank |
| Impact | N/A |
| Start Year | 2013 |
| Description | HCV Research UK - Gilead |
| Organisation | Gilead Sciences, Inc. |
| Country | United States |
| Sector | Private |
| PI Contribution | Provision of data from HCV Research UK to Gilead |
| Collaborator Contribution | Provision of data from HCV Research UK to Gilead |
| Impact | None as yet |
| Start Year | 2016 |
| Description | HCV Research UK - Gilead and University of Nottingham |
| Organisation | University of Nottingham |
| Department | School of Physics and Astronomy |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provision of data from HCV Research UK to University of Nottingham/Gilead. |
| Collaborator Contribution | Provision of data from HCV Research UK to University of Nottingham/Gilead for outcomes of use of DAAs for HCV-infected patients |
| Impact | Presentation accepted for poster at International Liver meeting |
| Start Year | 2016 |
| Description | HCV Research UK - Glasgow Royal Infirmary |
| Organisation | NHS Greater Glasgow and Clyde (NHSGGC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Glasgow Victoria Hospital |
| Organisation | NHS Greater Glasgow and Clyde (NHSGGC) |
| Department | NHS Greater Glasgow and Clyde Endowments |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Great Ormond Street |
| Organisation | Great Ormond Street Hospital for Children NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Heartlands Hospital |
| Organisation | Birmingham Heartlands Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in the HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N?A |
| Start Year | 2013 |
| Description | HCV Research UK - Hull Royal Infirmary |
| Organisation | Hull Royal Infirmary |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - James Cook, Middlesborough |
| Organisation | James Cook University Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Janssen |
| Organisation | Johnson & Johnson |
| Department | Janssen-Cilag |
| Country | Global |
| Sector | Private |
| PI Contribution | Provision of data from HCV Research UK to Janssen for NICE submission |
| Collaborator Contribution | HCV Research UK has provided data to Janssen following application to the Tissue and Data Access Committee. Selected data has been downloaded from the HCV Research UK database, quality controlled and then provided under an agreed contract. |
| Impact | Data used for submission to NICE. Likely publication to arise. |
| Start Year | 2013 |
| Description | HCV Research UK - John Radcliffe Hospital |
| Organisation | Oxford University Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - King's College Hospital |
| Organisation | King's College Hospital NHS Foundation Trust (NCH) |
| Department | Paediatric Services |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - LASER |
| Organisation | Laser Analytica |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Study program using electronic healthcare registers/databases |
| Collaborator Contribution | Financial contribution |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Leeds Children's Hospital |
| Organisation | Leeds Teaching Hospitals Charitable Foundation |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Leicester Royal Infirmary |
| Organisation | University Hospitals of Leicester NHS Trust |
| Department | Leicester Royal Infirmary |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Lincoln County Hospital |
| Organisation | United Lincolnshire Hospitals NHS Trust |
| Department | Lincoln County Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Manchester Royal Infirmary |
| Organisation | Manchester Royal Infirmary |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Monklands Hospital |
| Organisation | Monklands District General Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Ninewells Hospital and Medical School |
| Organisation | Ninewells Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - North Manchester General Hospital |
| Organisation | Pennine Acute Hospitals NHS Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Queen Alexandra Hospital, Portsmouth |
| Organisation | Queen Alexandra Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Queen Elizabeth Hospital, Birmingham |
| Organisation | Queen Elizabeth Hospital Birmingham |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Queen's Medical Centre |
| Organisation | Queen's Medical Centre |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Aberdeen Children's Hospital |
| Organisation | NHS Grampian |
| Department | Royal Aberdeen Children's Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Alexandra Hospital |
| Organisation | Brighton and Sussex University Hospitals NHS Trust |
| Department | Royal Alexandra Children's Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Blackburn Hospital |
| Organisation | East Lancashire Hospitals NHS Trust |
| Department | Royal Blackburn Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Derby Hospital |
| Organisation | Royal Derby Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Free Hospital |
| Organisation | Royal Free Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Hallamshire Hospital |
| Organisation | Sheffield Teaching Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Hospital for Sick Children, Glasgow |
| Organisation | Royal Hospital for Children |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Infirmary of Edinburgh |
| Organisation | NHS Lothian |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Lancaster Infirmary |
| Organisation | University Hospitals of Morecambe Bay NHS Foundation Trust |
| Department | Royal Lancaster Infirmary |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Liverpool University Hospital |
| Organisation | Royal Liverpool University Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Preston |
| Organisation | Royal Preston Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Shrewsbury |
| Organisation | Shrewsbury and Telford Hospital NHS Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Royal Sussex County Hospital, Brighton |
| Organisation | Royal Sussex County Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2014 |
| Description | HCV Research UK - Sandwell & City Hospitals, Birmingham |
| Organisation | Sandwell and West Birmingham Hospitals NHS Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Singleton Hospital, Swansea |
| Organisation | Singleton Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Southampton General |
| Organisation | Southampton General Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2013 |
| Description | HCV Research UK - Southern General Hospital |
| Organisation | Queen Elizabeth University Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - St Georges, London |
| Organisation | St George's NHS Trust, London |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - St James, Leeds |
| Organisation | St James's University Hospital (Jimmy's) |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - St Mary's Hospital |
| Organisation | St Mary's Hospital, London |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - St Mary's Paediatric |
| Organisation | St Mary's Hospital, London |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Provision of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Tayside Children's Hospital, Dundee |
| Organisation | Tayside Children’s Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - The Royal London Hospital, Whitechapel |
| Organisation | Royal London Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Uni Nottingham |
| Organisation | University of Nottingham |
| Department | Clinical Virology |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Dr John McLauchlan is co-chair of the HCV Research UK Steering Committee and, Management Group. He shares responsibility for the day-to-day running of HCV Research UK with Prof Will Irving. |
| Collaborator Contribution | Prof Will Irving is co-Chair of the HCV Research UK Steering Committee and, Management Group. He shares responsibility for the day-to-day running of HCV Research UK with Dr John McLauchlan. In addition, he acts as line manager for the Project Manager and oversees the co-ordination of the HCV Research UK network and clinical database. |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - University College Hospital |
| Organisation | University College Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - University Hospital Lewisham |
| Organisation | University Hospital Lewisham |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Western General Hospital |
| Organisation | NHS Lothian |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | HCV Research UK - Wycombe |
| Organisation | Buckinghamshire Healthcare NHS Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Inclusion of HCV samples in HCV Research UK biobank |
| Collaborator Contribution | Collection of HCV samples |
| Impact | N/A |
| Start Year | 2012 |
| Description | STOP-HCV |
| Organisation | STOP-HCV |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Provision of data and samples from HCV Research UK to STOP-HCV; sharing of know-how and data in viral sequeincing and host genotyping. |
| Collaborator Contribution | Sharing of know-how and data on viral sequencing and host genotyping. |
| Impact | Integrated studies on viral and host genetics. |
| Start Year | 2013 |
| Title | Target Enrichment for HCV Genomics |
| Description | This methodology improved the multiplexing and depth of coverage of HCV viral sequences compared to a more fundamental approach using metagenomics. The technology was developed to allow capture of viral sequences to very low levels (only a few hundred copies of viral genomes/ml). |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2016 |
| Impact | The approach is now being introduced to Public Health England for their diagnostic service to detect and identify HCV sequences. |
| Description | Abbvie Medical Team |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Organised an afternoon of speakers and presentations on a) HCV diagnostics now an din the future, b) sequencing methods for identifying resistance in patients who fail therapy and c) possible issues for difficult-to-treat patients with new therapies. |
| Year(s) Of Engagement Activity | 2014,2017 |
| Description | BBC News Story - HCV Alert Carol Leitch 23 February 2016 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Carol Leitch, at the request of Health Protection Scotland carried out the phylogenetic analysis of the 2 patient samples suspected of being infected by a healthcare worker in Lanarkshire. She was able to show that the HCV infecting these individuals was closely related and this was backed up by individuals from PHE who performed another analysis. This led to the realisation that these patients had likely been infected during a procedure carried out by the healthcare worker. This information formed the basis of a report submitted by NHS Lanarkshire to the UK Advisory Panel for Healthcare Workers Infected with Blood Borne Viruses and the national body endorsed the health board's proposal to carry out a patient notification exercise. 8383 patients treated by this healthcare worked will now be contacted and offered screening for HCV. As a result, the BBC featured a news story about the security alert- http://www.bbc.co.uk/news/uk-scotland-glasgow-west-35639826. This is an example how the work of the CVR has a direct influence on Policy, Practice, along with patients and public interests. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | BBC Scotland - Report on introduction of HCV into Scotland |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Media interview with BBC Scotland and release of information on BBC website. |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://www.bbc.co.uk/news/uk-scotland-34658098 |
| Description | Blog Post #4: Measles (Connor Bamford) - March 2015 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | This post received 179 views along with online comments and discussion, and likes and tweets on social media. Connor Bamford, the author of the post, received 4 emails providing positive feedback both from other CVR researchers but also from external colleagues, demonstrating that the blog was gaining further interest and was viewed in a positive light. |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | Blog for MRC Insight - 2013 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Blog written for MRC Insight to describe the aims of HCV Research UK. |
| Year(s) Of Engagement Activity | 2013 |
| URL | http://www.insight.mrc.ac.uk/2013/01/21/a-helping-hand-for-hepatitis-c-treatment/ |
| Description | CVR Blog #10 Viral Hepatitis - Connor Bamford July 2015 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Our 10th blog post about Hepatitis C infection. The blog post reached 776 people on Facebook and received 563 views. |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | CVR Blog #12 CVR at the Glasgow Science Festival - July 2015 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Our 12th blog showcased the CVR's activities at the Glasgow Science Festival in June 2015. The post reached 792 people on Facebook and received 183 views. |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | CVR Blog #17 ADAP2 Inhibition Connor Bamford October 2015 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Our 17th Blog post by Connor Bamford on the topic of ADAP2 inhibition and virus entry into cells. The post was viewed 144 times. |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | CVR Blog #7 Microtalks - Connor Bamford May 2015 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Our 7th Blog post promoting a CVR Glasgow Science Festival event. Reached 131 people on Facebook and received 160 views. |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | CVR Blog Post 2: Meet the Expert Dr John Mclachlan (Veronica Rezelj) - February 2015 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | 192 people read the blog post with likes reported on Facebook and Twitter. The increased number of views versus the first post demonstrated a heightened awareness of the blog and therefore, demonstrated an uplift in followers. |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | CVR Blog post 1: Hepatitis C Virus (Connor Bamford) - February 2015 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | The blog post encouraged online comments and discussion among readers. The post encouraged readers to follow the CVR blog therefore encouraging further future interaction and engagement. |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | Carol Monaghan MP visit - 30 October 2015 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Local MP of the Glasgow North West Constituency Carol Monaghan came to visit the CVR to meet with our Director Massimo Palmarini to learn about the important research carried out at the centre along with taking in a tour of the facility. Carol was able to meet with several of our researchers who provided short presentations about their research. Carol was very enthusiastic to learn about our research, links with industry and also about importance of funding. She then went on to mention the CVR and what she had learned during the visit at a parliamentary meeting in Westminster later that week. Furthermore, she then went on to visit one of the other Biomedical research centres that forms part of the University of Glasgow to gain a further insight into some of the important work and research being carried out across the University. |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | Clinical Staff - Invited Lecture on HCV Treatment |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented lecture on targets for new therapies for HCV infection and issues over drug resistance to clinicians and nursing staff. Feedback indicated that this improved knowledge of new treatments. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Connor Bamford - The Conversation Oct 2014 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Connor Bamford, CVR postdoc, discusses the shipment of an experimental Ebola vaccine to West Africa in a blog in The Conversation. Due to the popularity of Connor's blogs, he is now featured as a regular writer in this popular online publication. |
| Year(s) Of Engagement Activity | 2014 |
| URL | http://theconversation.com/high-hopes-rest-on-800-vials-of-experimental-ebola-vaccine-shipped-from-c... |
| Description | Engagement with support groups for HCV-infected patients |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | Yes |
| Type Of Presentation | Keynote/Invited Speaker |
| Geographic Reach | National |
| Primary Audience | Participants in your research and patient groups |
| Results and Impact | HCV Research UK has created a Steering Committee to oversee its activities. Patient support groups (HepC Trust and British Liver Trust) both have representatives on this committee. They are full members with the ability to comment on any plans for HCV Research UK. In addition, I have given oral presentations and led discussions with local and national HepC support groups (Hepatitis Scotland and Waverley Care). Patient groups feel part of the study and will be able to give feedback to their relevant groups. In addition, it enabled patients to ask questions about the types of research and clinical studies on new anti-viral compounds. |
| Year(s) Of Engagement Activity | 2011,2013 |
| Description | European Biobank conference, Vienna, Austria |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Presented invited lecture on HCV Research UK to illustrate the sustainability of biobanks to an international audience. |
| Year(s) Of Engagement Activity | 2016 |
| Description | HCV Research UK Launch January 2013 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | Yes |
| Geographic Reach | National |
| Primary Audience | Participants in your research and patient groups |
| Results and Impact | HCV Research UK is a multi-disciplinary collaborative enterprise funded by a £1.92m grant from the Medical Research Foundation and based at the MRC-University of Glasgow Centre for Virus Research. This ground breaking initiative has involved the development of a Bio-repository of clinical samples and cohort study of greater than 10,000 patients infected by Hepatitis C Virus (HCV). The database of information gathered about this cohort group is supporting the work of STOP-HCV and is also influencing prescribing decisions taken by the NHS. The information is also being made available for future research into HCV infection, thereby influencing and creating greater funding opportunities for research in this disease area. |
| Year(s) Of Engagement Activity | 2013,2014,2015 |
| URL | http://hcvresearchuk.org |
| Description | HCV Research UK Press Release December 2014 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | Yes |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | In November of 2014, HCV Research UK, a consortium of experts in the field of Hepatitis C Virus who are leading a ground-breaking cohort study of Hepatitis C Virus infected patients, reached a landmark point in the project - recruiting 10,000 patients to the study ahead of their target date of the 31st December 2014. As a result of this success, we circulated a press release to the national press to share the news and also shared a story in the December edition of MRC Life. The story featured in MRC Life, sharing this success story with other MRC Research Centres. The story was also features in the Viral Hepatitis in Practice publication in December 2014. |
| Year(s) Of Engagement Activity | 2014 |
| URL | http://www.gla.ac.uk/researchinstitutes/iii/cvr/news/headline_391453_en.html |
| Description | Hepatitis C Virus Origins Paper Press Release October 2015 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Following the publication of a CVR paper, which demonstrated the origins of Hepatitis C virus in Scotland, we issued a press release for distribution to the media. This resulted in news stories in several news papers including The Scotsman, The Herald, The Independent and the Daily Express as well as a feature on the BBC news website. Carol Leitch (one of the authors) also took part in an interview with BBC Radio Scotland. Links to stories as follows: http://www.bbc.co.uk/news/uk-scotland-34658098 http://www.thetimes.co.uk/tto/news/uk/scotland/article4599284.ece http://www.scotsman.com/news/health/scientists-track-hepatitis-c-roots-in-scotland-1-3930369#axzz3pwgMI6mV http://www.heraldscotland.com/news/homenews/13901425.Research_traces_hepatitis_C_infection_roots_to_Second_World_War/ http://www.thenational.scot/news/wartime-glasgow-study-offers-hope-in-hepatitis-c-battle.9 http://medicalxpress.com/news/2015-10-hepatitis-infections-scotland-wwii.html |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | ICGEB meeting on Human RNA Viruses, Costa Rica |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gave invited lecture and allowed advertising the CVR as an international centre for virological research. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.icgeb.org/rna-virus-workshop-2016.html |
| Description | Interviews |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | I have given interviews to journalists for newspapers. There was no further contact with the journalists and so it is difficult to judge any impact. |
| Year(s) Of Engagement Activity | 2006,2007 |
| Description | Invited Speaker at North of England Viral Hepatitis meeting |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited to present findings on possible resistance to new antiviral therapies for treating hepatitis C virus (HCV) infection to a group of clinicians, pharma representatives and nurses. Discussion centred on potential difficulties with natural strains that may be resistant and also retreatment for those patients in whom the drugs did not clear the virus. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Invited seminar speaker at the University of Hvidore, Denmark. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited to speak on the variability of hepatitis C virus (HCV) and the potential difficulties that this may pose for treating patients with new antiviral therapies. Discussion centred on the extent of variability of the virus as a possible problem for global eradication. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Invited speaker at a Gilead business event |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | The presentation was an update on possible resistance to novel antiviral therapies for treating hepatitis C virus (HCV) infection to the UK group of Gilead, a pharma company with drugs that have been approved for clinical use in HCV therapy. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Kelvingrove Museum Science Weekend |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | Yes |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | We ran our 'Build a virus' and 'One Infection' activities - offering participants the opportunity to learn all about the structure of viruses and also key messages related to the transmission of viruses, hygiene and vaccination. Participants were asked to provide feedback on the activities to help us determine how to improve the activity in future. We have been asked to submit a proposal to run an activity during the Glasgow Science Festival in June 2015. |
| Year(s) Of Engagement Activity | 2014 |
| Description | MRC Centenary Celebrations |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Type Of Presentation | Workshop Facilitator |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Over the course of two events in June 2013, we interacted with approximately 350 children and their families. We used these interactions to communicate some basic facts about viruses - focussing on their size, structure, routes of transmission and how to limit spread. As part of the activity, we asked participants to consider the question 'If you were a virology researcher what would you study?' and collected responses using post-it note feedback. This provided a good opportunity to discuss the impact of medical research (we often used vaccines as an example), and the importance of the support of the Medical Research Council to help scientists tackle some of the greatest health problems facing humanity. We have been invited to display the timeline at local schools and science centres across Scotland. |
| Year(s) Of Engagement Activity | 2013 |
| URL | http://www.virusesacenturyofdiscovery.org.uk |
| Description | MRC Festival of Medical Research |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | The event was aimed at individuals infected with hepatitis C virus (HCV) as well as carers, professionals and national support groups for those infected with the virus. The day was planned to include talks on various topics relevant to HCV-infected individuals (new treatments, likely outcomes, liver disease) and how the CVR was addressing these themes in its research portfolio. Feedback on the event was universally positive from those who attended. |
| Year(s) Of Engagement Activity | 2016 |
| Description | MRC Insight Publication |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Blog for MRC Insight to update activities associated with HCV Research UK and STOP-HCV. |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://www.insight.mrc.ac.uk/2015/07/28/finding-the-right-treatment-for-patients-with-hepatitis-c/ |
| Description | MRC Life - John McLachlan July 2015 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | Yes |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The article was posted on our Facebook and Twitter pages and encouraged online comments and likes. No notable impact. |
| Year(s) Of Engagement Activity | 2015 |
| URL | https://www.facebook.com/centreforvirusresearch/ |
| Description | NHS Research Scotland conference, QEUH, Glasgow |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture on STOP-HCV and HCV Research UK to demonstrate benefits of stratified medicine for treating HCV infection. |
| Year(s) Of Engagement Activity | 2016 |
| Description | National Forum for HCV |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented data on resistance identified in patients receiving new therapies for HCV infection to inform a national group about the possible importance of resistance testing. |
| Year(s) Of Engagement Activity | 2016 |
| Description | PCR workshop - Glasgow Science Centre |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | The workshop was organised by Dr D Bhella from the Unit and he will no doubt provide more comprehensive details. Both of the CDFs employed on the project volunteered their time and expertise for the workshop. As noted above, Dr D Bhella will most likely address this question on behalf of the Unit. |
| Year(s) Of Engagement Activity | 2009 |
| Description | Patient Group Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Hepatitis Scotland organised a national event (Hepatitis See) for patient groups across Scotland. I was an invited speaker and the presentation highlighted the importance of the scientific community to curing virus infection. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.eventbrite.co.uk/e/hepatitis-see-a-patient-conference-tickets-50681251989# |
| Description | Presentations to school children |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | Yes |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Formal presentation by PhD students to sixth form school children about their research projects at Glasgow Science Centre (2006 and 2008). Also regular contributions made by team members to workshops and demonstrations at Glasgow Science Centre and the Edinburgh Science Fair. Team members have also participated regularly in workshops at Schools Open Days hosted by our establishment (MRC Virology Unit) These activities have encouraged gifted school children about science. The formal talks in particular were very positively received by both pupils and teachers. |
| Year(s) Of Engagement Activity | 2006,2007,2008,2009 |
| Description | Scottish Society for Gastroenterology |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented lecture on targets for new therapies for HCV infection and issues over drug resistance to clinicians at a national conference. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Sheila Sherlock Updates, Royal Free London |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented invited lecture on targets for new therapies for HCV infection and issues over drug resistance to clinicians and academic staff. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Showcase Event - HCV Research UK |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The event was organised by the British Association for Study of the Liver/British Viral Hepatitis Groups to showcase consortia involved in HCV infection but primarily HCV Research UK. The purpose was to demonstrate the impact of HCV Research UK at the national level on collecting data and clinical samples to promote research into the virus, in particular with reference to the new therapies now available for treatment. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Sun Yat-Sen University, Guangzhou, China |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture to promote collaboration between CVR and Sun Yat-Sen University. The outcome was a collaboration with the Guangzhou Blood Centre, which led to a 1 year working visit by a senior member of their staff to the CVR. |
| Year(s) Of Engagement Activity | 2016 |
| Description | UK Clinical Pharmacists Association - Masterclass on HCV Treatment #1 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The workshop was aimed at clinical pharmacists to broaden their knowledge of new therapies for HCV infection and issues over drug resistance. Feedback from the event was that the presentation improved knowledge of new therapies and issues over their use. |
| Year(s) Of Engagement Activity | 2016,2017,2018 |
| Description | UK Clinical Pharmacists Association - Masterclass on HCV Treatment #2 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The workshop was aimed at clinical pharmacists to broaden their knowledge of new therapies for HCV infection and issues over drug resistance. Feedback from the event was that the presentation improved knowledge of new therapies and issues over their use. |
| Year(s) Of Engagement Activity | 2016 |
| Description | University of Leicester |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Undergraduate students |
| Results and Impact | Presentation on how different disciplines impact on virus research. |
| Year(s) Of Engagement Activity | 2016 |
| Description | presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | I have given a presentation to a HepC support group and been involved in fund-raising activities. Support groups are more aware of the activities funded by MRC to study HCV infection |
| Year(s) Of Engagement Activity | 2006 |
| Description | presentations |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | I have given practical demonstrations and talks at open days for schools. There are now well-established contacts with local schools and teachers. Students have expressed a greater interest in pursuing a scientific career after the open day events. |
| Year(s) Of Engagement Activity | 2006,2007,2008 |