Zika: A prospective case-control study to examine the role of Zika virus in Guillain-Barré syndrome in Brazil
Lead Research Organisation:
University of Liverpool
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
Guillain-Barré Syndrome (GBS) is an acute immune-mediated disease of the peripheral
nervous system which can lead to death or debilitating neurological disability. The number of
GBS cases in Zika-affected areas is rising sharply, but the WHO has urged caution in
attributing them to the virus. Through the Zika Neurology Network, established in 2015, we
will conduct a prospective case-control study of GBS in Rio de Janeiro, focusing on Zika as a
risk factor. The project builds on Liverpool expertise in flavivirus neurological disease, Public
Health England’s diagnostic capabilities, flavivirus research at the Oswaldo Cruz Foundation
(Fiocruz), Rio di Janeiro, and the International GBS Outcome Study’s experience.
We will recruit 60 adults with GBS referred to major hospitals in the Network, with scope to
expand if needed. GBS will be defined through recognised clinical and electrophysiological
criteria, and Zika infection diagnosed with investigations already established at Fiocruz,
including PCR of blood and urine, and IgM and IgG ELISA of blood. Outcome will be assessed
at 2 months. Four community controls will be recruited for each case.
Underpinned by the NIHR Health Protection Research Unit in Emerging and Zoonotic
Infections, which already has team members in Rio supporting protocol, case record form,
and diagnostic developments, the project provides excellent value for money, and is ready to
deliver in a timely manner. Within nine months our study will define the role of Zika as a risk
factor for GBS, to help individual patient management, and importantly to support public
health and policy decisions.
nervous system which can lead to death or debilitating neurological disability. The number of
GBS cases in Zika-affected areas is rising sharply, but the WHO has urged caution in
attributing them to the virus. Through the Zika Neurology Network, established in 2015, we
will conduct a prospective case-control study of GBS in Rio de Janeiro, focusing on Zika as a
risk factor. The project builds on Liverpool expertise in flavivirus neurological disease, Public
Health England’s diagnostic capabilities, flavivirus research at the Oswaldo Cruz Foundation
(Fiocruz), Rio di Janeiro, and the International GBS Outcome Study’s experience.
We will recruit 60 adults with GBS referred to major hospitals in the Network, with scope to
expand if needed. GBS will be defined through recognised clinical and electrophysiological
criteria, and Zika infection diagnosed with investigations already established at Fiocruz,
including PCR of blood and urine, and IgM and IgG ELISA of blood. Outcome will be assessed
at 2 months. Four community controls will be recruited for each case.
Underpinned by the NIHR Health Protection Research Unit in Emerging and Zoonotic
Infections, which already has team members in Rio supporting protocol, case record form,
and diagnostic developments, the project provides excellent value for money, and is ready to
deliver in a timely manner. Within nine months our study will define the role of Zika as a risk
factor for GBS, to help individual patient management, and importantly to support public
health and policy decisions.
People |
ORCID iD |
Publications
Walker LE
(2017)
A comparison of HMGB1 concentrations between cerebrospinal fluid and blood in patients with neurological disease.
in Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Griffiths MJ
(2018)
Management of acute meningitis.
in Clinical medicine (London, England)
Ellul M
(2018)
Acute encephalitis - diagnosis and management.
in Clinical medicine (London, England)
Griffiths MJ
(2018)
Response.
in Clinical medicine (London, England)
Birley HD
(2018)
Comment on CME Infectious diseases.
in Clinical medicine (London, England)
Howlett PJ
(2018)
Case Series of Severe Neurologic Sequelae of Ebola Virus Disease during Epidemic, Sierra Leone.
in Emerging infectious diseases
Grifoni A
(2017)
Global Assessment of Dengue Virus-Specific CD4+ T Cell Responses in Dengue-Endemic Areas.
in Frontiers in immunology
Subramaniam KS
(2020)
Two Is Better Than One: Evidence for T-Cell Cross-Protection Between Dengue and Zika and Implications on Vaccine Design.
in Frontiers in immunology
Cox JA
(2017)
Immunopathogenesis and Virus-Host Interactions of Enterovirus 71 in Patients with Hand, Foot and Mouth Disease.
in Frontiers in microbiology
| Description | Five years of collaborative research effort have led to a better understanding of the full clinical spectrum of congenital Zika syndrome in children and the neurological complications of Zika virus infections in adults and helped explore the origins and trajectory of Zika virus transmission. Individual-level data from ZikaPLAN`s cohort studies were shared for joint analyses as part of the Zika Brazilian Cohorts Consortium, the European Commission-funded Zika Cohorts Vertical Transmission Study Group, and the World Health Organization-led Zika Virus Individual Participant Data Consortium. Furthermore, the legacy of ZikaPLAN includes new tools for birth defect surveillance and a Latin American birth defect surveillance network, an enhanced Guillain-Barre Syndrome research collaboration, a de-centralized evaluation platform for diagnostic assays, a global vector control hub, and the REDe network with freely available training resources to enhance global research capacity in vector-borne diseases. |
| First Year Of Impact | 2016 |
| Sector | Healthcare |
| Impact Types | Policy & public services |
| Description | EAN-ESCMID Guidelines on Autoimmune Encephalitis |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Contribution to new or Improved professional practice |
| Description | EAN-ESCMID Guidelines on Infectious Encephalitis |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Contribution to new or Improved professional practice |
| Description | Member, Advisory Committee on Dangerous Pathogens, Department of Health and Social Care |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | Advises on all aspects of hazards and risks to workers and others from exposure to pathogens, such as transmissible spongiform encephalopathies, arthropod-borne viruses, and emerging pathogens such as Ebola, Zika and SARS-CoV-2. |
| Description | WHO Neuro-COVID surveillance group |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | Identified knowledge gaps to be targeted by future research. |
| URL | https://www.who.int/publications/i/item/WHO-2019-nCoV-Sci-Brief-Neurology-2021.1 |
| Description | Why Encephalitis Matters: Meeting Report |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | Recommendations to address global challenges posed by encephalitis published as meeting report. |
| URL | https://apps.who.int/iris/handle/10665/366223 |
| Description | A phase I study of recombinant poxvirus Zika vaccine. Co-applicant |
| Amount | £4,700,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2017 |
| End | 05/2021 |
| Description | Adjuvant free vaccines and companion diagnostics to control emerging flaviviruses. Co-applicant |
| Amount | £382,974 (GBP) |
| Funding ID | 971526 |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 01/2018 |
| Description | Clinical Research Career Development Fellowship (to Lance Turtle): Understanding cross-reactive immunity to Japanese encephalitis |
| Amount | £573,824 (GBP) |
| Funding ID | 205228/Z/16/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2017 |
| End | 07/2019 |
| Description | Development of a novel blood test to aid the diagnosis of bacterial meningitis. |
| Amount | £791,702 (GBP) |
| Funding ID | MR/R015406/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 05/2021 |
| Description | European Union Horizon 2020 |
| Amount | € 11,000,000 (EUR) |
| Organisation | European Union |
| Sector | Public |
| Country | European Union (EU) |
| Start | 10/2016 |
| End | 09/2020 |
| Description | Global Challenges Research Fund. One Health Regional Network for the Horn of Africa (HORN). Co-applicant |
| Amount | £7,700,000 (GBP) |
| Funding ID | BB/P027954/1 |
| Organisation | Research Councils UK (RCUK) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2017 |
| End | 10/2020 |
| Description | Global Health Research Group in Acute Brain Infections Principle Investigator |
| Amount | £1,999,761 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2018 |
| End | 07/2021 |
| Description | Health Protection Research Unit in Emerging and Zoonotic Infections - Extension. Chief Investigator / Director |
| Amount | £781,973 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2019 |
| End | 05/2020 |
| Description | Improving diagnosis of brain infections in Indonesia using novel and established molecular diagnostic tools. Co-applicant |
| Amount | £330,149 (GBP) |
| Funding ID | MR/S019960/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2019 |
| End | 01/2022 |
| Description | NIHR Senior Investigator |
| Amount | £15,000 (GBP) |
| Funding ID | NF-SI-0514-10177 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2015 |
| End | 03/2020 |
| Description | Senior Investigator |
| Amount | £60,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2023 |
| End | 03/2026 |
| Description | Zika: A prospective case-control study to examine the role of Zika virus in Guillain-Barré syndrome in Brazil |
| Amount | £150,000 (GBP) |
| Funding ID | MC_PC_15096 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 10/2017 |
| Description | A*STAR Singapore |
| Organisation | Agency for Science, Technology and Research (A*STAR) |
| Department | Singapore Immunology Network (SIgN) |
| Country | Singapore |
| Sector | Academic/University |
| PI Contribution | Partnership with Prof Lisa Ng on EV71 |
| Collaborator Contribution | Partnership with Prof Lisa Ng on EV71 |
| Impact | Non |
| Start Year | 2012 |
| Description | Brain Infections Global |
| Organisation | Oswaldo Cruz Foundation (Fiocruz) |
| Department | Fiocruz Pernambuco |
| Country | Brazil |
| Sector | Hospitals |
| PI Contribution | Collaboration on NIHR Global health Research Group |
| Collaborator Contribution | Collaboration on NIHR Global health Research Group |
| Impact | see publications |
| Start Year | 2019 |
| Description | Fast Track Diagnostics |
| Organisation | Fast Track Diagnostics Ltd. |
| Country | Malta |
| Sector | Private |
| PI Contribution | A new partnership where we evalutae new diagnostics |
| Collaborator Contribution | Development of kits |
| Impact | none yet |
| Start Year | 2014 |
| Description | Fundação Oswaldo Cruz, (FIOCRUZ) collaboration on Zika |
| Organisation | Oswaldo Cruz Foundation (Fiocruz) |
| Country | Brazil |
| Sector | Public |
| PI Contribution | Collaboration on Zika |
| Collaborator Contribution | Collaboration on Zika |
| Impact | New publications, and grants, see other sections |
| Start Year | 2016 |
| Title | University of Liverpool (Mike Griffiths/Tom Solomon) |
| Description | Diagnosing acute bacterial meningitis Our novel approach to distinguishing bacterial from viral brain infections by measuring host response genes in the blood has been patented and is due to be licenced soon with SME industrial partner with Fast Track Diagnostics |
| IP Reference | GB1606537.7 |
| Protection | Patent application published |
| Year Protection Granted | 2016 |
| Licensed | Yes |
| Impact | Strengthened collaboration with industrial partner FastTrack Diagnostics |
| Description | 17th International Symposium on NeuroVirology | 2021 Conference on HIV in the Nervous System - Plenary Talk, 2nd June 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | TS gave the plenary talk 'Neurological COVID - Causes, Complications, and Conundrums' at the 17th International Symposium on NeuroVirology | 2021 Conference on HIV in the Nervous System. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://isnv.org/virtual21/Agenda_ISNV_Virtual21.pdf |
| Description | BBC Radio Merseyside Interview with Roger Phillips, 19th August 2022 |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Tom Solomon was interviewed by Roger Phillips for BBC Radio Merseyside talking about his career. |
| Year(s) Of Engagement Activity | 2022 |
| Description | BNA2021 Festival of Neuroscience - COVID-19 and neuroscience talk, 14th April 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | TS gave a talk entitled 'Brain Infections Global COVID-Neuro Network' at Session two - Characterising COVID-19 with cohort studies: providing future evidence of the British Neuroscience Association conference. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://meetings.bna.org.uk/bna2021/programme_information/special-sessions/covid19/ |
| Description | BR?INCAST Podcast with Sotiris Posporelis and Dr Tom Pollack |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | BR?INCAST is a weekly 30-minute conversation with inspiring people from all around the world sharing their love about the most fascinating thing that happened to your headyour brain! From the microscopic magic of a molecular scientist to the all-encompassing worldview of a philosopher, from up-and-coming PhD students to well-established professors, BR?INCAST is open to everyone that's curious! Nah, it's not seriousthe brain is too interesting to be serious! Just cast your brain aside (see what I did there?) and enjoy. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://maudsleylearning.com/webinars-podcasts/braincast-webinar/world-encephalitis-day-experts-take... |
| Description | Brain Infections Webinars |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The webinars are held monthly in conjunction with The Global Health Network and are open sessions for policy makers, academics and clinicians. Initially the focus was on Covid-19 but in recent months has moved to a variety of Brain Infections. The learning objective of these webinars is to gain insights into practice in different settings through knowledge exchange with fellow participants. |
| Year(s) Of Engagement Activity | 2020,2021,2022 |
| URL | https://braininfectionsglobal.tghn.org/covid-neuro/webinars/ |
| Description | Chaired and presented in the Neuroinfection Session at The Brain Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tom Solomon presented 'Emerging Causes of Brain Infection' and chaired the Neuroinfection session at the 2021 Brain Conference. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://thebrainconference.co.uk/previous-conferences/ |
| Description | Covid for Kids - Barnes Children's Literature Festival, 27th June 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | This year's Barnes Children's Literature Festival presents particular challenges because of the pandemic. Luckily, Professor Tom Solomon an emerging infections expert at the centre of the UK response is on his way to Barnes with his new event, Covid for Kids at 1pm on Sunday 27th June, where you'll have the chance to ask him your questions! First up though, he answers a couple of ours! |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.barneskidslitfest.org/news/covid-for-kids-with-professor-tom-solomon/ |
| Description | Covid for Kids interview with Shelagh Fogarty |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Tom Solomon discussing his new Covid for kids show |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=D5uqzqmWN_c&t=57s |
| Description | Ebola threat to UK and Africa: Pollock and Solomon - BBC News Interview, 12th July 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | BBC interview with Professor Tom Solomon and Andrew Neil discussing the crisis and the transmission. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=3ETB4QIIM90&t=27s |
| Description | Encephalitis Society JE Masterclass for Australia Clinicians, 6th April 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tom participated in a Japanese Encephalitis masterclass hosted by the Encephalitis Society for Australian Clinicians. He gave a joint presentation with Ajit Rayamajhi on the management of JE in adults and children. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Granada Reports interview with Professor Tom Solomon discussing the impact in foreign aid reductio, 3rd July 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Granada Reports interview with Professor Tom Solomon, discussing the impact of funding cuts in scientific research. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=ReNB93y0si4 |
| Description | How to handle the pandemic | Edinburgh Science Festival 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | In late 2019 reports of an unknown virus began to emerge from the Chinese province of Hubei. 18 months later, the world is still in the grip of the worst pandemic in living memory, with over 3 million lives lost. Governments around the world have deployed a range of strategies to steer their nations through the crisis - but who got it right? This event brings together international experts who have advocated different approaches to attempt to find out how to handle a pandemic Hosted by Director of the UK's Emerging Infections Research Unit Tom Solomon, join Chair of the WHO's Global Outbreak Alert and Response Network Dale Fisher, behavioural scientist and Scottish government advisor Linda Bauld and epidemiologist Tim Spector for a keynote discussion. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=hyAgqn3tV1g |
| Description | ITV Granada Debate, 10th June 2021 |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Debate about local lockdowns, the spread of the variant, vaccinations and opening up on the 21st June. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=5FliX2m6bOg&t=44s |
| Description | Keynote at the Liverpool John Moores University Research Knowledge Exchange Conference, 7th December 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Undergraduate students |
| Results and Impact | Tom Solomon gave the keynote speech, The Global Fight Against Emerging Infections, at the Liverpool John Moores University Research and Knowledge Exchange Conference. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Keynote speech at World Encephalitis Day Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tom Solomon gave the keynote speech at the World Encephalitis Day Conference. He is President of the Encephalitis Society. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://wedconf.org/ |
| Description | Liverpool FC, Atletico Madrid, and the coronavirus outbreak - BBC Breakfast Interview, 17th March 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Tom Solomon contributes to this BBC Breakfast piece on the controversy around the football match played between Liverpool FC and Atletico Madrid at Anfield, which meant Spanish football fans would travel from Madrid, which at the time was experiencing an outbreak of the coronavirus. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=0JozskflxlI |
| Description | NIMH Neurologic and Psychiatric Effects of SARS-CoV-2 Meeting Presentation, 14th July 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | TS presented a talk titled 'CNS Manifestations of COVID-19 ' in Session I: Clinical Neurologic and Psychiatric Manifestations of Acute COVID-19. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.nimh.nih.gov/news/media/2021/neurologic-and-psychiatric-effects-of-sars-cov-2-meeting-da... |
| Description | Presentation at the JEV Outbreak in Australia Webinar, 17th March 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tom Solomon presented at the JEV Outbreak in Australia Webinar Lecture Series. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Prof Tom Solomon discusses the Commons Science and Technology Committee report BBC Breakfast News, 12th October 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Tom Solomon, Professor of Neurology and Director of the UK Emerging Infections Research Unit at the University of Liverpool talks to Charlie Stayt and Sally Nugent with Anita Astle, Director of Wren Hall nursing homes discusses the lessons learned and the initial UK Government response to Covid-19, compared to that of countries who had experienced SARS, MARS and other health crises in a new Public Health report on BBC Breakfast News on Tuesday 12 October 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=9BzzEqzAZbw |
| Description | Prof Tom Solomon discusses the new UK Government new Covid19 restrictions on BBC Breakfast News, 9th December 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Tom Solomon CBE, Professor of Neurology and Director of the UK Emerging Infections Research Unit at the University of Liverpool with Stephen Reicher, Professor of Social Psychology at the University of St. Andrews and member of the SAGE subcommittee talk to Charlie Stayt and Naga Munchetty about the UK Governments' new 'Plan B' Covid19 restrictions and how this intervention will mean lower community transmission of the new Omicron variant and fewer hospital admissions over the Festive season and beyond. Professors Solomon and Reicher also discuss the continued role of vaccination, self-isolation and ventilation in public settings in the run up to Christmas. Professor Solomon also re-emphasises the critical importance of vaccinating the rest of the world in the fight against new and emerging Covid19 variants. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=OqLFhAk2R0o |
| Description | Professor Tom Solomon featured on Roald Dahl Special - TRT Interview, 28th July 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Tom Solomon talk about Roald Dahl and book 'Marvellous Medicine' and more. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=jSA1ofjRPnw&t=15s |
| Description | Published book: Roald Dahl's Marvellous Medicine |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Popular Science Book, with associated tom radio, newspaper coverage talks, lectures, schools |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.tomsolomon.co.uk |
| Description | Radio 4 Interview Broadcasting House, 16th May 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | BBC Radio 4 Interview with Prof Tom Solomon and Paddy O'Connell 16th May 2021 |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=XA5YCmAphz8&t=50s |
| Description | Radio 5 live Covid for Kids interview, 25th June 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Tom Solomon promoting his Barnes Children's Literature Festival show, Covid for Kids - a family-friendly interactive show |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=SPsGpG6fGkY&t=1s |
| Description | Roald Dahl Interview - Times Radio, 17th March 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Professor Tom Solomon appears on Times Radio to discuss To Olivia, Sky's recent drama about the tragic loss of Roald Dahl and Patricia Neal's daughter, Olivia. Hosted by Daniel Finkelstein and also featuring To Olivia's producer, Donall McCusker. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=imvv1UDSknk |
| Description | Roald Dahl and some other Big Friendly Giants talk at the Wadham College Medics Event, 3rd September 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tom gave his talk 'Roald Dahl and some other Big Friendly Giants' to fellow alumni at the Wadham College Medics reunion event. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Roald Dahl's Marvellous Medicine, Family Show, presented at Edinburgh Festival Fringe |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Roald Dahl's Marvellous Medicine, Family Show, presented at Edinburgh Festival Fringe, and BBC, and West Ed Theatre (Leicester Square) . Audience >2000 in person. A chance to use a novel approach to explain some of our research (and other aspects of medical science) to a new audience. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Scouse Science Podcast - Host |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | The Scouse Science Podcast In front of a live online audience, award-winning science communicator, doctor and researcher Professor Tom Solomon hosts a regular discussion of cutting-edge science in Liverpool and its wider impact on society. In each program, Tom talks with a leading researcher on the scientific progress being made and chats about the broader implications with a famous face. |
| Year(s) Of Engagement Activity | 2020,2021,2022 |
| URL | https://www.liverpool.ac.uk/health-and-life-sciences/engage-with-us/scouse-science/ |
| Description | The anniversary of the first coronavirus lockdown in the NorthWest - ITV News Interview, 24th March 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Tom Solomon talks to Tim Scott, ITV News, on the anniversary of the first UK coronavirus lockdown, in a piece that looks back at the pandemic over the past year, and ahead to when the pandemic may end. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=Z6dmUJS-6_I&t=10s |
| Description | The new Omicron variant - Prof Tom Solomon on BBC Breakfast News, 6th December 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Tom Solomon CBE, Professor of Neurology and Director of the UK Emerging Infections Research Unit at the University of Liverpool talks to Dan Walker and Sally Nugent about the current unknowns of the new Omicron variant and the challenge of tweaking the current Covid19 vaccines. Tom also discusses the critical importance of vaccination not only to protect the UK but to protect the rest of the world, especially lower income countries. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=2YygKbibxIQ |
| Description | The new tablet to treat COVID-19 - Prof Tom Solomon CBE on BBC Breakfast News, 5th November 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Tom Solomon CBE, Professor of Neurology and Director of the UK Emerging Infections Research Unit at the University of Liverpool talks to Charlie Stayt and Naga Munchetty about the newly-approved Covid-19 drug treatment; Molnupiravir, how it was developed, it's effects and efficacy and who should be taking it. Tom also explains how the new Public Health Government ventilation recommendations launched today can be adopted over the festive period. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=a0ZA2ccrx_o |
| Description | Tom Solomon CBE talks with Naga Munchetty & Charlie Stayt, BBC Breakfast, about his honour. 12th June 2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Tom Solomon CBE is Naga and Charlie's first guest on the famous red sofa since the start of the pandemic, talking about receiving his award in the Queen's Birthday Honours List 2021. 12th June 2021 |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.youtube.com/watch?v=ncAj6MKFjdQ&t=355s |