Oxford P2D: From Technologies to Therapies

Lead Research Organisation: University of Oxford

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The MRC Proximity to Discovery scheme awards universities funds to help develop new collaborations, and ways of exchanging knowledge and skills.  The awards can be used to support activities that promote the value of academic-industry partnership, and enhance academic and industry researchers’ understanding of each other’s needs and capabilities.  This may be through people exchanges, creation of technology demonstrators, showcase events, commercialisation workshops and ‘entrepreneurs in residence’ schemes.  Such exchanges of knowledge and skills will boost the most fruitful collaborations between UK universities and life science companies.

Publications

10 25 50
 
Description Newton Institutional Links Fund (Turkey/UK): Investigation of Wnt-catenin signalling at the plasma membrane in health and disease
Amount £340,000 (GBP)
Organisation British Council 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2018 
End 01/2020
 
Description Collaboration with Merck 
Organisation Merck
Department Merck UK
Country United Kingdom 
Sector Private 
PI Contribution Visiting and discussing scientific collaboration with Merck and formation of Strategic Partnership between Merck and Oxford. We aim to establish deep collaborative working. Follow up teleconferences are in progress and there is huge optimism that this will work.
Collaborator Contribution Frequent discussions with Merck about strategic partnership
Impact This has just begun
Start Year 2016
 
Description Collaboration with Novonordisk Research Centre 
Organisation Novo Nordisk
Country Denmark 
Sector Public 
PI Contribution We are working together with the new Novonordisk Research Centre to genereate resources to facilitate the differentitation of human stem cells into mature endocrine beta-cells.
Collaborator Contribution We have generated constructs suitable enabling any stem cell line to be equipped with the machinery for site-specific genome editing. We are also working towards constructs which will enable lineage tracing during the differentiation of stem cells in vitro.
Impact The work has only just begun
Start Year 2018
 
Title Oxford Acute Myocardial Infarction (OxAMI) Study 
Description CMR Imaging to assess hyper-acute changes in the human myocardium after STEMI 
Type Diagnostic Tool - Imaging
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2018
Development Status Under active development/distribution
Impact Improved/accelerated research approaches 
 
Description Academic Industry Meeting Day- Biomedical Imaging 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Series of workshops based on questions led by industry on the theme of biomedical imaging: academics offered insight and possible solutions to the challenges. Impact includes a successful Innovate UK bid (£17.5M) amongst academic and industrial collaborators who met at this event.
Year(s) Of Engagement Activity 2018
URL http://www.ox.ac.uk/news/2018-11-06-oxford-secures-%C2%A3175-million-lead-national-ai-healthcare-pro...
 
Description Microscopy Workshop Izmir, Turkey 10.2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact Teaching of basics of optical microscopy to public/scientists in Turkey - funded by the British Council
Year(s) Of Engagement Activity 2017
 
Description Microscopy Workshop Lubljana, 9.2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact Teaching of basics of optical microscopy to public/students
Year(s) Of Engagement Activity 2017