Accelerating Translation at UCL – “UCL Confidence in Concept (CiC6) 2017”

Lead Research Organisation: University College London

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding. It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.

Publications

10 25 50
 
Description Brain injuries acquired during the neonatal period: investigating mechanisms which can correct depressed cortical electrical activity
Amount £298,114 (GBP)
Funding ID 201819-23 
Organisation Brain Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2020 
End 08/2023
 
Description EU SICM - Mervyn Singer - sepsis, membrane cholesterol levels
Amount € 20,000 (EUR)
Organisation European Society of Intensive Care Medicine (ESICM) 
Sector Charity/Non Profit
Country Belgium
Start 01/2020 
End 01/2022
 
Description Innovate UK- Laurence Lovatt - Caddie study
Amount £341,320 (GBP)
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start 04/2019 
End 04/2020
 
Description Medcity C2I ATMPs - Paola Bonfanti - engineered thymus
Amount £148,000 (GBP)
Organisation MedCity 
Sector Public
Country United Kingdom
Start 01/2020 
End 01/2022
 
Description Medtronic ERP grant ERP-2019-11996 - Robert Brownstone - multimodality imaging
Amount £146,884 (GBP)
Organisation Medtronic 
Sector Private
Country United States
Start 01/2020 
End 01/2022
 
Description RCP - Student stipend - Nikolitsa Nomikou - sonodynalic therapy in the treatment of pancreatic cancer
Amount £5,000 (GBP)
Organisation Royal College of Physicians of London 
Sector Learned Society
Country United Kingdom
Start 01/2020 
End 01/2021
 
Description RCS - Student stipend - Nikolitsa Nomikou - sonodynamic therapy in the treatment of pancreatic cancer
Amount £5,000 (GBP)
Organisation Royal College of Surgeons of England 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2020 
End 01/2021
 
Description Sentinell - Mariya Moosajee - PAX6-related aniridia
Amount £15,000 (GBP)
Organisation Sentinel Oncology 
Sector Private
Country United Kingdom
Start 05/2020 
End 12/2021
 
Description UK Space Agency - Lovatt (Odin Vision) - AI in colonoscopy
Amount £1,000,000 (GBP)
Organisation UK Space Agency 
Sector Public
Country United Kingdom
Start 09/2019 
End 09/2022
 
Title METHODS FOR TISSUE DECELLULARIZATION 
Description The present invention provides A method of producing a decellularised extracellular matrix (ECM) scaffold of at least a portion of a lobular organ with no common artery, the method comprising: a) closing afferent blood vessels to substantially seal a target lobular organ or portion thereof with no common and/or major artery within a non-human donor or a dead/brain dead human donor; b) optionally: (i) cleaning coagulum and/or blood from at least a portion of the closed afferent blood vessels; and/or (ii) perfusing the organ or portion thereof to confirm closure of the afferent blood vessels; c) removing the sealed organ or portion thereof from the donor; and d) perfusing the sealed organ or portion thereof with detergent and enzymatic solutions to obtain the decellularised ECM scaffold. Methods for producing an artificial organ, and artificial organs produced by the methods are also provided. 
IP Reference WO2019220091 
Protection Patent application published
Year Protection Granted 2019
Licensed No
Impact Still in development
 
Title Nanoparticles for Cancer Therapy and Diagnosis 
Description The present invention relates generally to methods and materials for use in photothermal or sonodynamic therapy. The invention novel nanoparticles for use in delivering sensitizers to solid tumour target, wherein the nanoparticles are composed of a polymers or co-polymer of monomers linked by peptide bonds, wherein the polymer or co-polymer comprises one or both of glutamate or derivatised glutatamic acid, and optionally a further, different, monomer which is a naturally occurring amino acid or synthetic monomer having a side chain group, wherein the polymer or co-polymer is not composed only of glutamate. The pendant groups and/or side chains of the polymer or co-polymer interact non-covalently with the sensitizer. 
IP Reference US2020330598 
Protection Patent application published
Year Protection Granted 2020
Licensed No
Impact In further development
 
Company Name Odin Vision 
Description Odin Vision, founded by a team of clinicians, medical imaging and artificial intelligence (AI) experts, is developing the next generation of AI enabled applications for endoscopic procedures. We believe that AI will create a new era of healthcare by supporting doctors to deliver higher quality care leading to improved patient outcomes and better value for healthcare payers. 
Year Established 2019 
Impact too early (- start-up)
Website https://odin-vision.com/