Proximity to Discovery: Scaling Up Industry Engagement Capability at the University of Bristol

Lead Research Organisation: University of Bristol

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The MRC Proximity to Discovery scheme awards universities funds to help develop new collaborations, and ways of exchanging knowledge and skills. The awards can be used to support activities that promote the value of academic-industry partnership, and enhance academic and industry researchers’ understanding of each other’s needs and capabilities. This may be through people exchanges, creation of technology demonstrators, showcase events, commercialisation workshops and ‘entrepreneurs in residence’ schemes. Such exchanges of knowledge and skills will boost the most fruitful collaborations between UK universities and life science companies.

Publications

10 25 50
 
Description Flexible Talent Mobility Award
Amount £16,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 12/2018 
End 03/2019
 
Description Innovate UK KTP with UCB (Moin Saleem)
Amount £150,000 (GBP)
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start 03/2019 
End 03/2021
 
Description Biogen Identifying the causal role of gene/protein expression on human diseases 
Organisation Biogen
Country United Kingdom 
Sector Private 
PI Contribution Expertise on Identifying the causal role of gene/protein expression on human diseases
Collaborator Contribution Application of expertise to drug development pipeline
Impact 1. in-house MR study on Biogen's drug target portfolio conducted and published 2. Sharing of datasets between Biogen and Bristol University 3. Conference talk given at the Mendelian Randomisation Conference 2019 4. Biogen to fund a three year post-doctoral post £300K 5. Conference paper accepted at ASHG conference 2020
Start Year 2018
 
Description Evotech and Bristol Renal 
Organisation Evotec
Country Germany 
Sector Private 
PI Contribution Kidney cell lines
Collaborator Contribution Funding for next phase of research
Impact £400k direct investment
Start Year 2018
 
Description External Advisory Board for MR Base 
Organisation Biogen
Country United Kingdom 
Sector Private 
PI Contribution Development of platform for using genetic data to predict the outcomes of clinical trials
Collaborator Contribution Membership of external advisory board
Impact External Advisory Board
Start Year 2018
 
Description External Advisory Board for MR Base 
Organisation Bristol-Myers Squibb
Department Celgene
Country United States 
Sector Private 
PI Contribution Development of platform for using genetic data to predict the outcomes of clinical trials
Collaborator Contribution Membership of external advisory board
Impact External Advisory Board
Start Year 2018
 
Description External Advisory Board for MR Base 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution Development of platform for using genetic data to predict the outcomes of clinical trials
Collaborator Contribution Membership of external advisory board
Impact External Advisory Board
Start Year 2018
 
Description External Advisory Board for MR Base 
Organisation Takeda Pharmaceutical Company
Country Japan 
Sector Private 
PI Contribution Development of platform for using genetic data to predict the outcomes of clinical trials
Collaborator Contribution Membership of external advisory board
Impact External Advisory Board
Start Year 2018
 
Description GSK Vaccines Neisserial vaccine development and evaluation 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution Neisserial vaccine development and evaluation
Collaborator Contribution Application of research to vaccine development pipeline
Impact GSK to fund PhD student for 3 years £150K. Disciplines include cellular and molecular medicine and population health.
Start Year 2018
 
Description GSK collaboration on Application of Mendelian randomization to predict therapeutic effect 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution Provided platform for using genetic data to predict the outcome of clinical trials
Collaborator Contribution Applied to above platform to pipeline of clinical trials
Impact Direct funding for post-doc
Start Year 2018
 
Description Medicines Discovery Catapult work on Modified Cytisiniclines as Novel and Selective Smoking Cessation Agents 
Organisation Medicines Discovery Catapult
Country United Kingdom 
Sector Private 
PI Contribution Modified Cytisiniclines as Novel and Selective Smoking Cessation Agents
Collaborator Contribution Acted as CRO
Impact Ongoing
Start Year 2019
 
Description Oracle cloud computing collaborations 
Organisation Oracle Corporation
Department Oracle Corporation UK Ltd
Country United Kingdom 
Sector Private 
PI Contribution Providing worked examples of biomedical research projects which would benefit from cloud computing
Collaborator Contribution Free cloud computing credits
Impact Collaboration across chemistry, population health and synthetic biology. Main impact is increasing computing speed dramatically.
Start Year 2018
 
Description Pfizer collaboration around paediatric vaccinations 
Organisation Pfizer Ltd
Country United Kingdom 
Sector Private 
PI Contribution Expertise in paediatric vaccines and access to local health and social care system
Collaborator Contribution Funding of centre for excellence
Impact Centre for Excellence funded.
Start Year 2018