BUILDING EDINBURGH’S DRUG DISCOVERY ECOSYSTEM

Lead Research Organisation: University of Edinburgh

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The MRC Proximity to Discovery scheme awards universities funds to help develop new collaborations, and ways of exchanging knowledge and skills. The awards can be used to support activities that promote the value of academic-industry partnership, and enhance academic and industry researchers’ understanding of each other’s needs and capabilities. This may be through people exchanges, creation of technology demonstrators, showcase events, commercialisation workshops and ‘entrepreneurs in residence’ schemes. Such exchanges of knowledge and skills will boost the most fruitful collaborations between UK universities and life science companies.

Publications

10 25 50
 
Description Attendance at ESACT drug discovery training course for 7 Post Docs 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Attendance at ESACT drug discovery training course for 7 Post Docs as part of a scheme to provide training and development opportunities for early career researchers.
Year(s) Of Engagement Activity 2019
 
Description Conducting digitally-enabled clinical trials seminar 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact The aim of the event was to start to build a community of interest including academia, industry, NHS and third sector, led by the Usher Institute, University of Edinburgh in the area of digitally enabled trials, given the work the Usher Institute is leading on with BREATHE and DataLoch, and encourage cross sector collaboration.

Max of 152 attendees; (up to 9 of these were not on the registration list)
Generally, 132 of the attendees stayed throughout.
- 27 of these attendees were from companies/industry and funders.
- Of these 27 attendees: 6 were from Funders/charities and 21 from industry/companies including attendees from:
• Biosignatures Ltd: Sarah Greenhalgh and Nicola McDade
• Altair Medical Limited: Bruce Henderson
• ONO Pharma UK Ltd: Tracey Lavery
• SOE Health Ltd: Neil Stentiford
• Galecto Biotech: Jie Wang
Year(s) Of Engagement Activity 2020
 
Description Development and Applications of 4D Cellular Medicine Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact The aim of the event was to bring together a small number (30-40) of select academics and relevant industry representatives to discuss needs, requirements and development of innovative disease-relevant models and the application of such models to study disease in both time and space and provide platforms and models to support drug discovery looking specifically at the multiparametric data and analytics and statistical models that allow innovation of such platforms and greater exploitation for drug discovery.
Year(s) Of Engagement Activity 2018
 
Description Drug Discovery Club Seminar - Case Studies 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact 35 people attended a talk by Damian Mole and Duncan Holmes on Drug Discovery Case Studies. Duncan Holmes from GSK presented the industry opinion and Damian Mole presented the academic viewpoint. It sparked questions and discussions afterwards and helped academics network with industry professionals.
Year(s) Of Engagement Activity 2019
 
Description Drug Discovery Club Seminar - Cell Based Technologies 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact A seminar as part of the Drug Discovery Club series, a speaker from the University of Edinburgh and Industry (Bio Ascent) giving presentations on advancements in cell based technologies for the purposes of drug discovery. The presentations were followed by a drinks reception for networking opportunities. The aim of this event series is education, networking and collaboration.
Year(s) Of Engagement Activity 2019
URL https://www.eventbrite.co.uk/e/drug-discovery-club-cell-based-technologies-tickets-53916041331
 
Description Drug Discovery Club Seminar - Drug Screening 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact 35 people attended a talk by Dr Stuart McElroy and Prof Catherine Becker on Drug Screening techniques. Dr Stuart McElroy presented the industry opinion and Prof Catherina Becker presented the academic viewpoint. It spaked questions and discussions afterwards and helped academics network with industry professionals.
Year(s) Of Engagement Activity 2019
 
Description Drug Discovery Club Seminar - Target Validation I 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact A seminar with an industry speaker and University of Edinburgh speaker highlighting the importance of Target Identification & Validation in drug discovery process, providing examples from clinical-stage programmes. The seminar was followed by a drinks reception for networking.
Year(s) Of Engagement Activity 2018
URL https://www.eventbrite.co.uk/e/drug-discovery-club-target-validation-i-tickets-49132151588
 
Description ENNP Industry & Ferring Pharamaceuticals and Medicxi engagement 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact As part of the early spin-out activities that have been conducted by the partner Universities, the team has had interactions and received positive feedback from a number of investor groups (e.g. LifeArc, Epidarex, Medixci, SROne, Advent, NovoSeeds) and pharma/biotech companies (Ferring and Evotec). These interactions have been highly supportive of the expertise of the founding team, the target rationale, the molecules arising from the programme to date and the potential of the platform as a whole. They have also underlined the need to advance the programme through further optimisation to provide molecules that can be assessed in vivo in pharmacological models of fibrosis. We have recently applied for additional funding via Scottish Enterprise (SEHGSP) to support development of the lead programme through to the end of full preclinical development, representing an established value inflection point for industry. We will continue to update these groups on our progress, and will, in addition, approach other potential funding groups to assess interest. Further industry feedback regarding the proposed spin-out company's areas of activity will be sought through the extensive personal and professional contacts of the team (e.g. Abbvie, AstraZeneca, Eli Lilly, GSK) as part of the developing customer discovery strategy undertaken by the founders.
Year(s) Of Engagement Activity 2018
 
Description Magee Women's Research Institute Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Attended conference and set up collaboration between Edinburgh University and Magee Women's Health researchers.
Year(s) Of Engagement Activity 2018
 
Description Post Doc Career Seminar - Denise Barrault 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Denise Barrault presented 20 Post Docs with his career journey to inspire food for thought for their own career options. It was an informal event which helped to foster a goof Q&A session with the speaker.
Year(s) Of Engagement Activity 2020
 
Description Post Doc Career Seminar - Jon Moore 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Jon Moore presented 18 Post Docs with his career journey to inspire food for thought for their own career options. It was an informal event which helped to foster a goof Q&A session with the speaker.
Year(s) Of Engagement Activity 2019
 
Description Post Doc Career Seminar - Neil Carragher 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Neil Carragher presented 25 Post Docs with his career journey to inspire food for thought for their own career options. It was an informal event which helped to foster a goof Q&A session with the speaker.
Year(s) Of Engagement Activity 2019
 
Description Post Doc Careers Seminar - David Jenkinson 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A Post Doc careers seminar to demonstrate to University of Edinburgh Post Docs that there is a variety of translational and commercial career opportunities available to them. David Jenkinson from the Brain Tumour Charity presented.
Year(s) Of Engagement Activity 2019
 
Description Post Doc Careers Seminar - David Jenkinson 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact David Jenkinson presented 15 Post Docs with his career journey to inspire food for thought for their own career options. It was an informal event which helped to foster a goof Q&A session with the speaker.
Year(s) Of Engagement Activity 2019
 
Description Post Doc Careers Seminar - Debbie Wake 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A Post Doc careers seminar to demonstrate to University of Edinburgh Post Docs that there is a variety of translational and commercial career opportunities available to them. Debbie Wake from My Way Digital Health presented.
Year(s) Of Engagement Activity 2021
 
Description Post Doc Careers Seminar - Denise Barrault 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A Post Doc careers seminar to demonstrate to University of Edinburgh Post Docs that there is a variety of translational and commercial career opportunities available to them. Denise Barrault from National Phenotypic Screening Centre presented.
Year(s) Of Engagement Activity 2020
 
Description Post Doc Careers Seminar - Jon Moore 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A Post Doc careers seminar to demonstrate to University of Edinburgh Post Docs that there is a variety of translational and commercial career opportunities available to them. Jon Moore from Advent Life Sciences presented.
Year(s) Of Engagement Activity 2019
 
Description Post Doc Careers Seminar - Lysimachos Zografos 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A Post Doc careers seminar to demonstrate to University of Edinburgh Post Docs that there is a variety of translational and commercial career opportunities available to them. Lysimachos Zografos from Edinburgh Innovations presented.
Year(s) Of Engagement Activity 2020
 
Description Post Doc Careers Seminar - Mary Canning 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A Post Doc careers seminar to demonstrate to University of Edinburgh Post Docs that there is a variety of translational and commercial career opportunities available to them. Mary Canning from Epidarex presented.
Year(s) Of Engagement Activity 2020
 
Description Post Doc Careers Seminar - Neil Carragher 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A Post Doc careers seminar to demonstrate to University of Edinburgh Post Docs that there is a variety of translational and commercial career opportunities available to them. Neil Carragher from Edinburgh University presented.
Year(s) Of Engagement Activity 2019
 
Description Post Doc Careers Seminar - Philipp Gramlich 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A Post Doc careers seminar to demonstrate to University of Edinburgh Post Docs that there is a variety of translational and commercial career opportunities available to them. Philipp Gramlich from Natural Science Careers presented.
Year(s) Of Engagement Activity 2019
 
Description Post Doc Careers Seminar - Philipp Gramlich 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Phillip Gramlich presented 40 Post Docs with his career journey to inspire food for thought for their own career options. It was an informal event which helped to foster a goof Q&A session with the speaker.
Year(s) Of Engagement Activity 2019
 
Description Prof Andrew Horne attendance at the Womens Health Research Institute Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Prof Andrew Horne attendance at the Womens Health Research Institute Conference in Pittsburg to meet with respresentatives from the Magee Womens Health Research Institute to discuss a collaboration for novel diagnostic blood test for endometriosis.
Year(s) Of Engagement Activity 2018