IMPRINT: IMmunising PRegnant women and INfants neTwork

Lead Research Organisation: London Sch of Hygiene and Trop Medicine

Abstract

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Technical Summary

The Industrial Challenge Strategy Fund supplement is designed to bring diverse and flexible pump-priming activities to the Network with additional industrial involvement. This award will provide a support linkage, increasing UK Vaccine R&D activity around ‘proof of concept’ studies and can be used to support academic-industry partnerships and enhance academic and industry researchers' understanding of each other's needs and capabilities. This may be through people exchanges, creation of tecnology demonstrators, showcase events, workshops and pump-priming of grant activities.
 
Title Videos about IMPRINT - our passion, global network, our innovative approach and impact on the life of mothers and infants 
Description We taped videos during our IMPRINT full network meeting (for more details, please refer to the Engagement activity section). We let two people have conversations on why they joined the network, the benefits of our network, our innovative approach and the impact on the life of mothers and infants. the half an hour interviews/conversations were cut together to approx one minute clips and are presented on our website. We aim to show our passion for our network, why it is important and why more people should join. 
Type Of Art Film/Video/Animation 
Year Produced 2018 
Impact After the meeting, we received new membership applications and feedback from the meeting participants that the videos caught perfectly the spirit of the network. 
URL http://www.imprint-network.co.uk
 
Description Advisory Board Maternal Immunisation
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Via setting up immunisation services in antenatal clinics we have improved uptake
 
Description The Advancing Maternal Immunization collaboration (AMI) analysis report on respiratory syncytial virus (RSV) maternal immunization
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Beate Kampmann, our IMPRINT network PI, and Naor Bar-Zeev, our challenge 6 co-lead, joined 58 other individuals across 25 organizations in 14 countries to publish the AMI gap analysis report on respiratory syncytial virus (RSV) maternal immunization . The Advancing Maternal Immunization collaboration (AMI), coordinated by PATH in collaboration with the WHO, brings together diverse stakeholders from around the world and across immunization and maternal, newborn, and child health programs to identify a pathway to enable informed decision-making and introduction of maternal RSV vaccines, particularly in LMICs, and to provide tools to help decision-makers, implementers, researchers, and others navigate that pathway successfully.
URL https://www.path.org/resources/advancing-rsv-maternal-immunization-gap-analysis-report/
 
Description British Columbia University 
Organisation University of British Columbia
Department Department of Pediatrics
Country Canada 
Sector Academic/University 
PI Contribution provided support for field sample collections and vaccinations, plus laboratory facilities
Collaborator Contribution access to protocols
Impact publication, presentation at international meeting, visibility
Start Year 2014
 
Description Collaboration with MRC/GCRF funded International Veterinary Vaccinology Network, University of Edinburgh, UK 
Organisation University of Edinburgh
Department The Roslin Institute
Country United Kingdom 
Sector Academic/University 
PI Contribution The MRC/GCRF funded sister "Networks in Vaccine R&D" Hic-Vac, BactiVac, IntVetVacc, Validate and IMPRINT support each other by exchange of knowledge, administrative issues, the network PIs supporting network meeting by presenting their own networks and joint presentation of the networks during the BSI meeting 2017 (please refer to Engagement activities for more details).
Collaborator Contribution The MRC/GCRF funded sister "Networks in Vaccine R&D" Hic-Vac, BactiVac, IntVetVacc, Validate and IMPRINT support each other by exchange of knowledge, administrative issues, the network PIs supporting network meeting by presenting their own networks and joint presentation of the networks during the BSI meeting 2017 (please refer to Engagement activities for more details).
Impact Joint meeting attendance. Exchange of knowledge on reporting to funders and administrative matters.
Start Year 2017
 
Description Collaboration with MRC/GCRF funded network Hic-Vac, Imperial College, UK 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution the MRC/GCRF funded sister "Networks in Vaccine R&D" Hic-Vac, BactiVac, IntVetVacc, Validate and IMPRINT support each other by exchange of knowledge, administrative issues, the network PIs supporting network meeting by presenting their own networks and joint presentation of the networks during the BSI meeting 2017 (please refer to Engagement activities for more details).
Collaborator Contribution the MRC/GCRF funded sister "Networks in Vaccine R&D" Hic-Vac, BactiVac, IntVetVacc, Validate and IMPRINT support each other by exchange of knowledge, administrative issues, the network PIs supporting network meeting by presenting their own networks and joint presentation of the networks during the BSI meeting 2017 (please refer to Engagement activities for more details).
Impact Joint meetings and exchange of knowledge on reporting and administrative issues.
Start Year 2017
 
Description Collaboration with the MRC/GCRF funded network BactiVac, University of Birmingham, UK 
Organisation University of Birmingham
Country United Kingdom 
Sector Academic/University 
PI Contribution The MRC/GCRF funded sister "Networks in Vaccine R&D" Hic-Vac, BactiVac, IntVetVacc, Validate and IMPRINT support each other by exchange of knowledge, administrative issues, the network PIs supporting network meeting by presenting their own networks and joint presentation of the networks during the BSI meeting 2017 (please refer to Engagement activities for more details).
Collaborator Contribution The MRC/GCRF funded sister "Networks in Vaccine R&D" Hic-Vac, BactiVac, IntVetVacc, Validate and IMPRINT support each other by exchange of knowledge, administrative issues, the network PIs supporting network meeting by presenting their own networks and joint presentation of the networks during the BSI meeting 2017 (please refer to Engagement activities for more details).
Impact Joint meeting attendance. Exchange of knowledge on reporting to funders and administrative matters.
Start Year 2017
 
Description Collaboration with the MRC/GCRF funded network Validate , University of Oxford, UK 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution The MRC/GCRF funded sister "Networks in Vaccine R&D" Hic-Vac, BactiVac, IntVetVacc, Validate and IMPRINT support each other by exchange of knowledge, administrative issues, the network PIs supporting network meeting by presenting their own networks and joint presentation of the networks during the BSI meeting 2017 (please refer to Engagement activities for more details).
Collaborator Contribution The MRC/GCRF funded sister "Networks in Vaccine R&D" Hic-Vac, BactiVac, IntVetVacc, Validate and IMPRINT support each other by exchange of knowledge, administrative issues, the network PIs supporting network meeting by presenting their own networks and joint presentation of the networks during the BSI meeting 2017 (please refer to Engagement activities for more details).
Impact Joint meeting attendance, exchange of knowledge on reporting to funders and administrative matters.
Start Year 2017
 
Description Harvard Levy lab 
Organisation Boston Children's Hospital
Country United States 
Sector Hospitals 
PI Contribution exchange of staff and technology
Collaborator Contribution contributed research samples
Impact publication by Burl et al
Start Year 2010
 
Description Harvard Levy lab 
Organisation University College London
Department Institute of Child Health
Country United Kingdom 
Sector Academic/University 
PI Contribution exchange of staff and technology
Collaborator Contribution contributed research samples
Impact publication by Burl et al
Start Year 2010
 
Description ICH London Goldblatt lab 
Organisation University College London
Department Institute of Child Health
Country United Kingdom 
Sector Academic/University 
PI Contribution scientific exchange re pneumococcal immunisation policies, practice and research, sharing of reagents and assay development
Collaborator Contribution scientific exchange re pneumococcal immunisation policies, practice and research, sharing of reagents and assay development
Impact 1 shared PhD studentship, scientific workshop at MRC The Gambia input into senior appointments
Start Year 2012
 
Description Imperial College London, UK; Dr Holder 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Dr Holder is member of our network Steering Committee
Collaborator Contribution Dr. Beth Holder is a Lecturer in Maternal and Fetal Health in the Institute of Reproductive Biology (IRDB) and our IMPRINT challenge 1 "Mechanism of production and transfer of maternal antibody via the placenta and breast milk" co-lead. She supports the network with her expertise.
Impact IMPRINT joint events (e.g. London Midwifery Festival, please refer to the section Engagement Activities) and publications. MatImms App for pregnant women (please refer to Engagement Activities).
Start Year 2017
 
Description Johns Hopkins Bloomberg School of Public Health, USA; Dr Bar-Zeev 
Organisation Johns Hopkins University
Department Johns Hopkins Bloomberg School of Public Health
Country United States 
Sector Academic/University 
PI Contribution Narr Bar-Zeev is one of our IMPRINT Steering Committee members
Collaborator Contribution Dr Naor Bar-Zeev is a pediatric infectious diseases physician and statistical epidemiologist. His research interest is in understanding how to maximise the benefit of existing and future vaccines in low-resourced high mortality settings, how best to protect vulnerable groups like newborns and pregnant women and how to optimise methods to evaluate vaccine impact and effectiveness. He is part of our IMPRINT Steering Committee and challenge 6 "Development of comparable methodologies for assessing efficacy in clinical trials" co-lead.
Impact Joint IMPRINT events.
Start Year 2017
 
Description Levy Lab 
Organisation Boston Children's Hospital
Department Levy Laboratory
Country United States 
Sector Hospitals 
PI Contribution set up of systems vaccinology research for studies of EPI vaccines
Collaborator Contribution bioinformatics support
Impact several publications and a grant submission to the nIH
Start Year 2014
 
Description London School of Hygiene and Tropical Medicine and the Vaccine Confidence Project, UK, Prof. Larson 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Heidi Larson is a member of our IMPRINT Steering Committee.
Collaborator Contribution Prof. Heidi J. Larson is an anthropologist and Director of The Vaccine Confidence Project™ (VCP); Professor of Anthropology, Risk and Decision Science, Dept. Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine; Clinical Professor, Institute of Health Metrics & Evaluation, University of Washington; and Chatham House Centre on Global Health Security Fellow. She is a member of our IMPRINT Steering Committee and one of our challenge 4 "Vaccine acceptancy and preparedness for maternal immunisation, including in emergencies" co-leads. IMPRINT is featured as a partner on the vaccine confidence.org website (please refer to Engagement activities for more details).
Impact Joint IMPRINT events.
Start Year 2017
 
Description MRC Unit The Gambia 
Organisation Medical Research Council (MRC)
Department MRC Unit, The Gambia
Country Gambia 
Sector Public 
PI Contribution cross-fertilisation between nIHR funding and my role at the MRC Unit in The Gambia, where I hold a TB related program grant
Collaborator Contribution program grant on childhood TB embedded within the MRC Unit
Impact several publications and program grant award
Start Year 2010
 
Description National Health Services, UK; Dr Mehring-Le Doare 
Organisation National Health Service
PI Contribution Dr Kirsty Mehring-le Doare is one of our IMPRINT Steering Committee members.
Collaborator Contribution Dr Mehring is consultant in Paediatric Infectious Diseases and Immunology, CSAC Training Advisor (PIID). She also functions as one of our IMPRINT Steering Committee members and co-lead of our challenge "Mechanism of production and transfer of maternal antibody via the placenta and breast milk".
Impact Joint IMPRINT events and publications.
Start Year 2017
 
Description Oxford Vaccine Group 
Organisation University of Oxford
Department Oxford Vaccine Group
Country United Kingdom 
Sector Academic/University 
PI Contribution mutual engagement in Vaccinology research
Collaborator Contribution joint supervision of PhD student
Impact new collaboration
Start Year 2014
 
Description PATH 
Organisation PATH
Country Global 
Sector Private 
PI Contribution Path vaccine roadmap work
Collaborator Contribution scientific advice
Impact funding
Start Year 2016
 
Description Public Health England 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution a database was developed by my team, funded from the NIHR award, to capture household contacts, which is now used by PHE as the contact tracing module within the national TB notifications
Collaborator Contribution PHE supported the database developer who was based at Colindale during the time of database development
Impact is now used by PHE as the contact tracing module within the national TB notifications
Start Year 2010
 
Description University of Liverpool, Prof. French 
Organisation University of Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution Neil French is member of our IMPRINT Steering Committee
Collaborator Contribution Neil French is Professor of Infectious Diseases and Global Health and Hon Consultant Infectious Diseases Royal Liverpool & Broadgreen University Hospitals Trust. He is a member of our IMPRINT Steering Committee and challenge 6 "Development of comparable methodologies for assessing efficacy in clinical trials" co-lead.
Impact Joint IMPRINT events and publications.
Start Year 2017
 
Description University of Oxford, UK; Dr Drakesmith 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Alexander Drakesmith is member of our IMPRINT Steering Committee
Collaborator Contribution Dr Drakesmith´s lab is at the Weatherall Institute of Molecular of Medicine where he studies the role of iron in infectious diseases and the immune response. He is member of our IMPRINT Steering Committee and challenge 3 "Impact of globally important co-factors on maternal and neonatal immunity" co-lead.
Impact Joint IMPRINT events.
Start Year 2017
 
Description University of the Witwatersrand, South Africa; Dr Clare Cutland 
Organisation University of the Witwatersrand
Department Respiratory And Meningeal Pathogens Unit
Country South Africa 
Sector Academic/University 
PI Contribution Clare Cutland is one of our network Executive Committee members.
Collaborator Contribution Dr. Clare Cutland is the Deputy Director at the Respiratory and Meningeal Pathogens Research Unit (RMPRU) based at Chris Hani Baragwanath Academic Hospital (CHBAH), Soweto, South Africa. She has been a sub-investigator/ senior doctor on numerous phase I, II and III paediatric vaccine trials and principal investigator on a phase II paediatric measles vaccine trial and a phase III quadrivalent influenza vaccine trial in children. She is part of our IMPRINT Steering committee group and co-lead of our challenge "Vaccine Safety and Monitorgin in LMIC".
Impact Joint events related to IMPRINT. Publications are currently in preparation.
Start Year 2017
 
Description Blog feature MatIMMS project, Patient Experience Research Center Imperial College London 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact The MatImms project consists of a multi-disciplinary research team of midwives, doctors and scientists that investigates vaccination in pregnancy. The project is led by Prof. Beate Kampmann. MatImms encourages vaccination in pregnancy to protect newborn babies from preventable infections. In the laboratory, MatImms studies the impact of vaccines on immunity in mothers and babies. In order to connect with pregnant women, the MatImms Smartphone App has been developed to improve vaccine information available, enabling pregnant women and their support networks to make informed choices. Our challenge 1 co-lead Beth Holder co-developed the App and its contents. IMPRINT is mentioned on the blog news.
Year(s) Of Engagement Activity 2019
URL http://wwwf.imperial.ac.uk/blog/perc/2019/02/11/case-study-15-matimms-involve-women-in-research-addr...
 
Description Impact Science Report 2018 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact IMPRINT was featured in the latest Impact Science Report. Our network PIs Beate Kampmann and Chrissie Jones talked about the "value of vaccination in pregnancy". They discussed our innovative and game-changing network activities as well as the network´s long-term global impact. Our IMPRINT fellow Alansana Darboe is also featured and shares how the IMPRINT fellowship will foster his research career. The article aimed at increasing our visibility and attract new members.
Year(s) Of Engagement Activity 2018
URL http://impact.pub/December2018-2digitaledition/
 
Description RE:Action 2017, Magazin of the University of Southampton 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Chrissie Jones and IMPRINT were featured in the The RE:Action Magazine of the University of Southampton, Re:action is the University of Southampton's bi-annual Research and Enterprise newsletter offering insight into public policy related research conducted at the University as well as public engagement and business activities. the article aimed to increase our visibility and attract potential new members to the network.
Year(s) Of Engagement Activity 2017
URL https://e.issuu.com/anonymous-embed.html?u=university_of_southampton&d=web_version_reaction_magazine...