University of Nottingham – Confidence in Concept 2019

Lead Research Organisation: University of Nottingham
Department Name: UNLISTED

Abstract

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Technical Summary

The Confidence in Concept (CIC) scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions to flexibly support a portfolio of early stage translational research projects. CIC is designed to accelerate the transition from discovery research to viable translational projects by supporting preliminary studies to establish proof-of-concept so that the approach will then become competitive for more substantial translational funding.

People

ORCID iD

Publications

10 25 50
 
Description Designing bio-instructive materials for translation ready medical devices
Amount £4,074,945 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 01/2023 
End 01/2027
 
Description ICURe Award to Prof. Chappell
Amount £31,337 (GBP)
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start  
 
Description Impact Accelerator Award to Prof. Shaw / Dr Clifford
Amount £19,000 (GBP)
Organisation University of Nottingham 
Sector Academic/University
Country United Kingdom
Start 07/2022 
End 07/2023
 
Company Name ISOMAB LTD 
Description IsomAb is developing isoform specific, humanised IgG1 based antibodies and it has identified, using a combined bioinformatics/knowledge-based platform approach, its first antibody against Vascular Endothelial Growth Factor A (VEGF-A). Our strategy utilises an antibody to specifically inhibit the VEGF-A165b isoforms; based on 20 years of research, the evidence shows this isoform is key to preventing collateral vessel formation in ischemic diseases. 
Year Established 2022 
Impact IsomAb is a pre-clinical stage company with Proof-of-Concept data, in two animal models, and an ambitious plan to take its first product into the clinic by 2026.
Website https://www.isomab.bio/