Stratification of MRC funded scientific technologies and reagents for rapid and simple dissemination to the wider scientific community
Lead Research Organisation:
University of Dundee
Department Name: UNLISTED
Abstract
Reagents and technologies will be accessed via a web-based resource similar to PPU’s current model (https://mrcppureagents.dundee.ac.uk/) or (https://dub-screen.mrc.ac.uk/). Reagents and technologies will be distributed from the Dundee facility or from the relevant MRC Unit where appropriate. Centralisation of a catalogue of reagents and technologies as well as the administration and distribution systems under a single web-based access point will greatly enhance the open science and translational outputs of MRC funded research to both academia and industry.
Technical Summary
Reagents and technologies will be accessed via a web-based resource similar to PPU’s current model (https://mrcppureagents.dundee.ac.uk/) or (https://dub-screen.mrc.ac.uk/). Reagents and technologies will be distributed from the Dundee facility or from the relevant MRC Unit where appropriate. Centralisation of a catalogue of reagents and technologies as well as the administration and distribution systems under a single web-based access point will greatly enhance the open science and translational outputs of MRC funded research to both academia and industry.
People |
ORCID iD |
| Dario Alessi (Principal Investigator) |
Publications
Armstrong L
(2021)
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
in PLOS ONE
Rihn SJ
(2021)
A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research.
in PLoS biology
| Title | Distribution of MRC funded Reagents and Technologies through a central hub |
| Description | Project underway to centralise the listing and distribution of outputs from all MRC establishments through a central hub. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2021 |
| Provided To Others? | Yes |
| Impact | Project in early stages - impact will be that all MRC funded reagents and technologies will be accessible through a central hub. |
| URL | https://resources.mrc.ukri.org |
| Description | MRC Reagents and Services Hub |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The formation of a National Hub to list and distribute reagents and scientific technologies to the research community across the globe. We host the hub, websites and laboratories to enable this. |
| Collaborator Contribution | Each partner lists their outputs on our website and we distribute these to academics and industry on request. |
| Impact | The collaboration is in its early stages with the Scotland part of the project near completion. Once up and running, the outcomes will be the access to all MRC funded reagents and technologies under a single MRC branded website. |
| Start Year | 2021 |
| Description | MRC Reagents and Services Hub |
| Organisation | University of Glasgow |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The formation of a National Hub to list and distribute reagents and scientific technologies to the research community across the globe. We host the hub, websites and laboratories to enable this. |
| Collaborator Contribution | Each partner lists their outputs on our website and we distribute these to academics and industry on request. |
| Impact | The collaboration is in its early stages with the Scotland part of the project near completion. Once up and running, the outcomes will be the access to all MRC funded reagents and technologies under a single MRC branded website. |
| Start Year | 2021 |
| Description | Connect and collaborate Parkinson's outreach event in the School of Life Sciences |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | On November 7 of this year, the chief executive team of Parkinson's UK including CEO Caroline Rassell, Deputy director of research Professor David Dexter and the new Scotland director James Jopling visited the Parkinson's research team at the University of Dundee. In the morning, researchers from Dundee including Professor Dario Alessi, Dr. Paul Davies, ProfessorMiratul Muqit, Dr. Andy Howden, Professor Ian Ganley and Dr. Esther Sammler, from Aberdeen Professor Bettina Platt and Julie Jones, from St. Andrews Doris Chen and from Edinburgh, Professor Tilo Kunath gave an overview of their work. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Interview with Journalist from Bloomberg News |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | On Thursday 19th January, I spent ~90 minutes talking with Robert Langreth, a Journalist from Bloomberg News, on the subject of Pakrinson disease, Alzheimer's and other neurological diseases. Robert was looking to write a story on where the efforts for parkinson's disease modifying drugs stand. Robert was interested in finding out more about lrrk2 and parkinson's disease research. Robert advised he had also spoken with the MJFF and ASAP re how the influx of funding from MJFF/Sergey Brin/Asap is changing things, and how is the approach taken in parkinson's differ from the more single minded focus in Alzheimer's. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Meeting with UoD alumni |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | Myself, and other members of SLS, participated in an event which welcomed medics who graduated from Dundee University in 1977. I discussed with them the current research that is taking place in our Unit and beyond in Dundee. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Pursuing a breakthrough for Parkinson's |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Pursuing a breakthrough for Parkinson's |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.dundee.ac.uk/stories/pursuing-breakthrough-parkinsons |
| Description | Rallying to the Challenge - a general discussion |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | On Wednesday 8th September, myself, Miratul Muqit and Esther Sammler held a recorded a general discussion with Marc Van Greiken and Helen Matthews for the Cure Parkinson's trust on the research that we are doing in Dundee. This talk will be shown at a special 2021 conference for people with Parkinson's called "Rallying" that will have a worldwide audience. Rallying is a meeting for people with Parkinson's with the agenda designed by and with people living with Parkinson's. It is based on the Grand Challenges which were in person meetings held at the Van Andel Institute in Michigan. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://cureparkinsons.org.uk/rallying-to-the-challenge-2021/ |