GCRF: Trauma and Adverse Childhood Experiences Springboard (TrACES)

Lead Research Organisation: University of Exeter

Abstract

GCRF: Trauma and Adverse Childhood Experiences Springboard (TrACES) is a programme of pump priming funding that will be competitively allocated to academics and groups of academics within the University of Exeter to develop sustainable relationships with specified LMIC countries as part of an evolving global research platform.
The primary aim of this platform is to harness existing expertise and knowledge among UK researchers on early life trauma (including adverse childhood experiences) and the mechanisms and pathways leading from such trauma to a spectrum of mental health, substance and violence-related outcomes, and expand this into collaborative research partnerships with
LMIC researchers working in this field. Such collaboration across diverse global settings will allow for adaptation of existing methodologies and co-creation of new approaches and research understanding in this neglected but critically important field.
The life-course trajectories leading from early life trauma to mental illness, substance use problems, and violent behaviours, have devastating personal and societal outcomes; and these impacts have particular importance for LMIC contexts where the burden is heaviest. These health and behavioural outcomes carry a huge human and socio-economic cost and threaten to undermine these nations' ability to achieve sustainable development targets.
There is an imperative therefore to collaborate across global contexts and across scientific disciplines to broaden and enrich the evidence base in this field. This future evidence-base needs to answer questions including how early experiences of trauma may lead to harmful mental health outcomes; how some individuals are resilient and remain well despite early adversities; and how these developmental pathways may differ between varied social, economic and cultural
contexts.
The TRACES programme of funding will be for the first stage of establishing this global research platform. TRACES aims to springboard the building of global relationships and networks across disciplinary boundaries with the goals of a) making these partnerships sustainable b) prioritising the strengthening of research capacity across collaborations c) generating necessary pilot data and d) and winning large-scale competitive research awards that will support long-term programmes of research in this field. Ultimately, this research will provide the evidence for developing interventions that are effective and
relevant to context.
While TRACES has a particular emphasis on partnerships with South Africa, we are also partnering with other LMICS (Uganda, India, Jamaica, Guyana and Colombia. Within the bounds of this funding, our emphasis on South Africa is strategic as we have particularly strong existing relationships with researchers in that country and are thus confident of
success and realising immediate impact within the 12-month period of the award.
Our funding programme comprises three different funding mechanisms or entry levels that can springboard relationships with LMIC research partners. These are:
- Strategic Fund: 3-9 month pilot projects of £20-30k that will be used to collate preliminary data or developing methodologies in relation to specific research questions where a relationship within an LMIC is already established.
- Network Development: This stream will fund a series of workshops and network events, £10-30k, with LMIC partners and collaborators.
- Link Funds: These funds are about scoping the potential for further collaboration within LMICs. The award will fund up to £10k for a single workshop/meeting or exchange with an LMIC partner where there is not already an established
relationship; and, if successful, awardees will be encouraged to upgrade to application for a network development award if feasible.

Technical Summary

TRACES is a collaborative programme of research between the University of Exeter (UoE) and partners in South Africa, Uganda, India, Jamaica, Guyana and Colombia focused on early life trauma (including adverse childhood experiences) and its trajectories to mental illness, substance abuse and violence-related outcomes. Early life trauma (ELT) is highly
prevalent, especially within low- and middle-income countries (LMICs) and is strongly associated with a wide spectrum of mental illness (including psychosis, mood and anxiety disorders, addictions, suicide and personality disorders). The major part of the global burden of these disorders is located in LMICs, yet research on the mechanisms and pathways through
which ELT interacts with other aetiologies and leads to later mental illness is limited outside of high-income contexts.
Research to date suggests that early trauma acts through epigenetic processes, disregulates hypothalamo-pituitaryadrenal pathways and immunological processes and disrupts cognitive-affective development. There is an urgent need to
investigate these and other mechanisms within diverse geographical, social and cultural contexts so as to move forward our understanding and provide a basis for developing and testing interventions aimed at mitigating the effects of ELT and preventing consequent mental, substance and violence-related outcomes.
Adopting a developmental life-course perspective and a translational approach including multidisciplinary methods (i.e. genomics and epigenomics, neuroimaging, psychopharmacology, clinical, social and spatial epidemiology, cognitive and experimental neuroscience and neuropsychology), this programme provides pump-priming funding to support collaborative workshops, network-building and pilot studies that will establish our international research platform and provide a
springboard for large-scale, multidisciplinary and collaborative grant applications that will enable this ambitious programme of research.

Publications

10 25 50
 
Description GCRF Facilitation Fund - Supporting families affected by mental illness in Minsk region, Belarus
Amount £29,952 (GBP)
Organisation University of Exeter 
Sector Academic/University
Country United Kingdom
Start 12/2018 
End 07/2019
 
Description Establishing a mixed methods research network for cross-national research in trauma-related mental health with Colombia 
Organisation Pontifical Xavierian University
Country Colombia 
Sector Academic/University 
PI Contribution The project costs are in three parts: 1. Time costed for project researchers. 23 days contracted rate for PI, 23 days bought out for CoI 2. Travel, accommodation and subsistence costs for two UoE researchers to visit the Colombian site and conduct workshops, meetings and site visits. 2x return flights for UoE researchers (one each). 2x return train fares to relevant airport (Heathrow or Gatwick). Accommodation in Colombia (2x7 nights). Living expenses (3 meals a day for 7 days, x 2 researchers). Travel to intervention sites within Colombia. 3. Money for administrative assistance in Bogota to organise workshop series. Amount to be specified by Colombian colleagues. Materials for workshops. Printing, photocopying costs. The College will be providing the 20% shortfall on fEC as matched funding.
Collaborator Contribution Colombian colleagues can match funding in kind. In particular, they will match in kind with: 1. Time for the two Colombian researchers 2. Pontificia Universidad Javeriana is willing to provide the rooms where the workshop will take place, with appropriate technology (powerpoint or similar). 3. All lunch meals for the two British researchers will be provided as well as all meals and accommodation during the weekend. Coffee-breaks would be provided by the University to 15 participants during the workshop.
Impact Still active
Start Year 2018
 
Description Genomic trajectories to mental health in India 
Organisation National Institute of Mental Health and Neurosciences
Country India 
Sector Hospitals 
PI Contribution A key aspect of this project will be to establish and develop collaborations between researchers in Exeter and NIMHANS. We have therefore requested funds to cover a kick-off/networking meeting in Year 1 to be held in either Exeter or Bangalore. This will cover international airfare and a weeks accommodation/subsistence for two persons (estimated cost per person = £1,500). Total: £3,000. The project will conclude with a genomics/bioinformatics training workshop to be held in Bangalore. This will cover international airfare and a weeks accommodation/subsistence for four persons (estimated cost per person = £1,500), in addition to £2500 costs associated with running the workshop (catering, printing costs, travel for participants, etc). Total: £8,500. The remainder of the available funding will be used to cover epigenomic profiling experiments. It is estimated that for the available £25,000 we will be able to profile approximately 100 samples. The University of Exeter Medical School will cover 2% time for PIs and CoIs on this project.
Collaborator Contribution NIMHANS in Bangalore will cover salary costs for all involved in the project. It is estimated that collaborators will spend 2-5% of their time on the project, with other NIMHANS participants spending ~2% time on the project. The project also leverages upon considerable investments made in sample collection, clinical phenotyping and brain-banking in Bangalore.
Impact Still ongoing
Start Year 2018
 
Description How can parenting programmes be adapted and/or generic parenting practitioners be trained to respond appropriately to women and children who have experienced trauma, in particular domestic violence and abuse? 
Organisation University of Cape Town
Country South Africa 
Sector Academic/University 
PI Contribution Costs requested include a small amount of time for an administrator in each site to organise the workshops, including bookings and catering. We have claimed for room hire in London but not in Johannesburg because we will make use of a venue at ISS. We have costed to provide tea and coffee at the workshops as well as a sandwich lunch for 15-20 people. Travel costs include international travel for 2 people from the UK to travel to the SA workshop, and 2 people from South African to travel to London for the UK workshop. In addition, we have included costs to allow us to sponsor the local travel (and in certain cases accommodation) of UK and SA charity or public sector workshop participants. We have also costed for a facilitator. Judy Connors is an experienced facilitator and specialist practitioner in the field of GBV prevention. The additional resources requested will enable greater participation by charitable/public sector delegates from other provinces in South Africa at the Johannesburg workshop and for an additional South African delegate to attend the London meeting. The Principle Investigator's time on the project (10 days) will be matched funded also.
Collaborator Contribution The ISS in Johannesburg will provide the venue for the South African workshop free of charge. Collaborator time will be covered by their respective organisations (7 days each).
Impact Still active
Start Year 2018
 
Description Indigenous methods of dealing with the consequences of early life adversity 
Organisation Ayahuasca Foundation
PI Contribution TBC
Collaborator Contribution TBC
Impact Still active
Start Year 2018
 
Description Indigenous methods of dealing with the consequences of early life adversity 
Organisation Pontifical Catholic University of Peru
Country Peru 
Sector Academic/University 
PI Contribution TBC
Collaborator Contribution TBC
Impact Still active
Start Year 2018
 
Description TRauma Pathways to mental Illness in the Caribbean and Africa (TRoPICA) 
Organisation Makerere University
Country Uganda 
Sector Academic/University 
PI Contribution Two Network-related events are planned: a TRoPICA Network meeting over 3 days in Durban, South Africa to be attended by all collaborative partners and to be held between May and end of July 2018; and a smaller meeting over 2 days in Exeter of core partner representatives from each of the collaborating sites to be held by end of November 2018. Funds are requested for the Network meeting in Durban for international return economy flights to Durban for 9 people and domestic economy return flights for 2 people from Cape Town. In addition funds are requested for hotel accommodation (4 nights) and for hotel transfers for the 11 visitors to Durban. Funding for lunches and dinners for 11 visitors and 4 locals (15) over the 3 days of the meeting are requested. Finally, we request funds for the hiring of a hotel conference venue (for 15 people) in Durban for 3 days. Funds are requested for a November 2018 meeting of core site PI partners in Exeter over 2 days. This includes international return economy flights for 5 people and return train ticket to Exeter from London for 1 person. Funding for hotel accommodation in Exeter for 6 visitors for 3 nights is requested, as well as for airport/hotel/St Lukes taxi transfers over the 3 days for the 6 visitors. Finally, funds are requested for lunches and dinners over 3 days for the 8 participants in this 2 day meeting. Salary contributions in-kind from College of Health Sciences for Exeter staff salaries are at 5% FTE for 12 months for PI and at 2% FTE for 12 months for CoI.
Collaborator Contribution Network Development
Impact Still active
Start Year 2018
 
Description TRauma Pathways to mental Illness in the Caribbean and Africa (TRoPICA) 
Organisation University of KwaZulu-Natal
Country South Africa 
Sector Academic/University 
PI Contribution Two Network-related events are planned: a TRoPICA Network meeting over 3 days in Durban, South Africa to be attended by all collaborative partners and to be held between May and end of July 2018; and a smaller meeting over 2 days in Exeter of core partner representatives from each of the collaborating sites to be held by end of November 2018. Funds are requested for the Network meeting in Durban for international return economy flights to Durban for 9 people and domestic economy return flights for 2 people from Cape Town. In addition funds are requested for hotel accommodation (4 nights) and for hotel transfers for the 11 visitors to Durban. Funding for lunches and dinners for 11 visitors and 4 locals (15) over the 3 days of the meeting are requested. Finally, we request funds for the hiring of a hotel conference venue (for 15 people) in Durban for 3 days. Funds are requested for a November 2018 meeting of core site PI partners in Exeter over 2 days. This includes international return economy flights for 5 people and return train ticket to Exeter from London for 1 person. Funding for hotel accommodation in Exeter for 6 visitors for 3 nights is requested, as well as for airport/hotel/St Lukes taxi transfers over the 3 days for the 6 visitors. Finally, funds are requested for lunches and dinners over 3 days for the 8 participants in this 2 day meeting. Salary contributions in-kind from College of Health Sciences for Exeter staff salaries are at 5% FTE for 12 months for PI and at 2% FTE for 12 months for CoI.
Collaborator Contribution Network Development
Impact Still active
Start Year 2018
 
Description TRauma Pathways to mental Illness in the Caribbean and Africa (TRoPICA) 
Organisation University of Stellenbosch
Country South Africa 
Sector Academic/University 
PI Contribution Two Network-related events are planned: a TRoPICA Network meeting over 3 days in Durban, South Africa to be attended by all collaborative partners and to be held between May and end of July 2018; and a smaller meeting over 2 days in Exeter of core partner representatives from each of the collaborating sites to be held by end of November 2018. Funds are requested for the Network meeting in Durban for international return economy flights to Durban for 9 people and domestic economy return flights for 2 people from Cape Town. In addition funds are requested for hotel accommodation (4 nights) and for hotel transfers for the 11 visitors to Durban. Funding for lunches and dinners for 11 visitors and 4 locals (15) over the 3 days of the meeting are requested. Finally, we request funds for the hiring of a hotel conference venue (for 15 people) in Durban for 3 days. Funds are requested for a November 2018 meeting of core site PI partners in Exeter over 2 days. This includes international return economy flights for 5 people and return train ticket to Exeter from London for 1 person. Funding for hotel accommodation in Exeter for 6 visitors for 3 nights is requested, as well as for airport/hotel/St Lukes taxi transfers over the 3 days for the 6 visitors. Finally, funds are requested for lunches and dinners over 3 days for the 8 participants in this 2 day meeting. Salary contributions in-kind from College of Health Sciences for Exeter staff salaries are at 5% FTE for 12 months for PI and at 2% FTE for 12 months for CoI.
Collaborator Contribution Network Development
Impact Still active
Start Year 2018
 
Description TRauma Pathways to mental Illness in the Caribbean and Africa (TRoPICA) 
Organisation University of West Indies
Country Jamaica 
Sector Academic/University 
PI Contribution Two Network-related events are planned: a TRoPICA Network meeting over 3 days in Durban, South Africa to be attended by all collaborative partners and to be held between May and end of July 2018; and a smaller meeting over 2 days in Exeter of core partner representatives from each of the collaborating sites to be held by end of November 2018. Funds are requested for the Network meeting in Durban for international return economy flights to Durban for 9 people and domestic economy return flights for 2 people from Cape Town. In addition funds are requested for hotel accommodation (4 nights) and for hotel transfers for the 11 visitors to Durban. Funding for lunches and dinners for 11 visitors and 4 locals (15) over the 3 days of the meeting are requested. Finally, we request funds for the hiring of a hotel conference venue (for 15 people) in Durban for 3 days. Funds are requested for a November 2018 meeting of core site PI partners in Exeter over 2 days. This includes international return economy flights for 5 people and return train ticket to Exeter from London for 1 person. Funding for hotel accommodation in Exeter for 6 visitors for 3 nights is requested, as well as for airport/hotel/St Lukes taxi transfers over the 3 days for the 6 visitors. Finally, funds are requested for lunches and dinners over 3 days for the 8 participants in this 2 day meeting. Salary contributions in-kind from College of Health Sciences for Exeter staff salaries are at 5% FTE for 12 months for PI and at 2% FTE for 12 months for CoI.
Collaborator Contribution Network Development
Impact Still active
Start Year 2018
 
Description TRauma Pathways to mental Illness in the Caribbean and Africa (TRoPICA) 
Organisation University of the West Indies at St. Augustine
PI Contribution Two Network-related events are planned: a TRoPICA Network meeting over 3 days in Durban, South Africa to be attended by all collaborative partners and to be held between May and end of July 2018; and a smaller meeting over 2 days in Exeter of core partner representatives from each of the collaborating sites to be held by end of November 2018. Funds are requested for the Network meeting in Durban for international return economy flights to Durban for 9 people and domestic economy return flights for 2 people from Cape Town. In addition funds are requested for hotel accommodation (4 nights) and for hotel transfers for the 11 visitors to Durban. Funding for lunches and dinners for 11 visitors and 4 locals (15) over the 3 days of the meeting are requested. Finally, we request funds for the hiring of a hotel conference venue (for 15 people) in Durban for 3 days. Funds are requested for a November 2018 meeting of core site PI partners in Exeter over 2 days. This includes international return economy flights for 5 people and return train ticket to Exeter from London for 1 person. Funding for hotel accommodation in Exeter for 6 visitors for 3 nights is requested, as well as for airport/hotel/St Lukes taxi transfers over the 3 days for the 6 visitors. Finally, funds are requested for lunches and dinners over 3 days for the 8 participants in this 2 day meeting. Salary contributions in-kind from College of Health Sciences for Exeter staff salaries are at 5% FTE for 12 months for PI and at 2% FTE for 12 months for CoI.
Collaborator Contribution Network Development
Impact Still active
Start Year 2018
 
Description Traumatic brain injury (TBI) and adolescent violence in diverse settings 
Organisation University of Cape Town
Country South Africa 
Sector Academic/University 
PI Contribution - The workshops will enable us to establish key groups at Exeter University to then provide input into workshop in SA to enable planning of the study. At Ex U we will have staff from: Psychology (Neuropsychology, Clinical and Drug and Alcohol), Medical School, and Computing & Engineering and Law - We will also have key attendees from data management companies in looked after children and criminal justice and from policy and practice - The workshops will allow for consideration of study design (if requires modification) and/or stakeholder engagement in dissemination and implementation of findings. With OXrisk - we can design studies to further refine the system to predict violence post TBI/ - and with Do-It Profiler - build on existing links in SA for enhancing their systems to manage young offenders with health issues. - Establish a group in SA with LSE for linkage between UK and SA - from various departments at CTU and government agencies in SA. - Cover costs of data acquisition and management and running supplementary analyses with participants in SA - The College will provide research staff costs time for PI
Collaborator Contribution The collaborator has secured funding from NRF Thuthuka grant for contributions towards the research. This allows for support for operating costs for projects with post-graduate students in SA. This covers costs for the outcomes study but not MRI component - which is why partial funds were requested towards MRI.
Impact Still active
Start Year 2018
 
Description Understanding and building resilience to early life trauma in Belarus and Ukraine 
Organisation Ukrainian Catholic University
PI Contribution Travel: We would like to request funds for participant travel to each workshop. We expect up to 10 participants from Ukraine to travel to the two workshops in Belarus and vice versa for the one workshop in Ukraine. Local travel costs are requested for participants attending workshops within-country. Funds are needed for PI and CoI to travel to the 3 workshops (Belarus x 2, Ukraine x 1) and a meeting to identify research priorities/next steps (Ukraine x 1). We would also like to request costs for one international speaker for workshop 1 and 2 (based on flight from London) and 3 participants from within CEE for workshop 3. We have checked visa requirements for Belarus and Ukraine, and there is no cost implication for workshop participants. Accommodation: We will need to cover accommodation costs for international workshop participants. This covers two nights x 11 participants (10 from Belarus/Ukraine plus one international speaker) x 3 workshops; plus three nights for PI and CoI x 3 workshops. A further two nights accommodation is also needed for PI, CoI and a representative from one partner organisation to attend the final meeting to discuss next steps/research priorities. Subsistence: refreshments, lunch and dinner will be needed on Day 1 of each workshop, and refreshments and lunch will be provided on Day 2. Subsistence will also be needed for participants at the final project meeting. Administration: The costs of employing a local administrator in Belarus and Ukraine are requested to help organise the workshops. Each workshop will require up to twenty working days of an administrator's time (Belarus x 2 workshops, Ukraine x 1 workshop). Translation: Translation between English, Russian and Ukrainian will be required for each workshop. This will ensure that language is not a barrier to participation. Printing and dissemination: One report will be produced per workshop, as well as a final report. We will need costs for printing, as well as for dissemination across Belarus, Ukraine and (for the third workshop and final report) the wider CEE Region. Virtual network: Costs are requested for set up of a virtual network (website development and hosting costs) to ensure on-going collaboration, networking and exchange of best practice that will feed into development of further work. Costs are also requested for two staff (one in each country) to collate initial information and manage the network (months 3-12).
Collaborator Contribution Partners will provide staff time in kind for workshop organisation, delivery and reporting. This amounts to approx. £430 (US$600) in Belarus and £215 (US$300) in Ukraine (based on partners giving one month of their time to the project). Total = £645. To ensure sustainability and on-going networking and collaboration, partners have committed to provide staff time to oversee and update the virtual network after the completion of the project funding period. Both partners will provide venues for the workshops free of charge, equivalent to £70 (US$100) per event. Total = £210 Partners will seek conference bursaries (available for Eastern European participants) to cover costs of presenting the work at the German Association for Psychiatry, Psychotherapy and Psychosomatics conference, Nov/Dec. 2018. Similarly, the next European Psychiatry Association conference falls outside of timeline of project so we will source cost elsewhere.
Impact Still active
Start Year 2018
 
Description Understanding pathways from childhood trauma to psychiatric illness to drug dependence 
Organisation University of Stellenbosch
Country South Africa 
Sector Academic/University 
PI Contribution The cost of the two meetings/workshops, plus the accompanying conferences, have been roughly estimated given that prices cannot be determined in advance, but the estimate is broadly accurate. Any remaining funds will be returned to the pool by the middle of Nov 2018 (after the second meeting), for re-distribution before the termination date of the fund in Feb 2019. We might request the use of surplus funds to support research activity in discussion with the fund manager as the project develops.
Collaborator Contribution N/A
Impact Still active
Start Year 2018
 
Description Epigenetics in Health and Disease, National Institute of Mental Health and Neuro Sciences Bangalore, INDIA 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Conference Schedule
Day 1
9:30 am: Introduction
9:45 am - 11:00 am : Keynote: Epigenomic pathways to neuropsychiatric and neurodegenerative disease - Prof Jonathan Mill, Professor of Epigenetics, University of Exeter Medical School, UK
11:00 am - 11:15 am : Tea
11:15 am -12:15 pm : Epigenetics of schizophrenia: from twins to cells -Dr Emma Dempster, Lecturer, University of Exeter Medical School, UK
12:15 pm- 1:15 pm : Mining the Human Genome for Epigenetic Tool kit - Prof Vani Brahmachari, Professor, ABCR, University of Delhi
1:15 pm - 2:30 pm : Lunch and Poster Session
2:30 pm - 3:30 pm : Nutrition: An epigenetics perspective -Dr Arpita Mukhopadhyay, Division of Nutrition, SJRI, Bangalore
3:30 pm - 4:30 pm : Modelling antipsychotic exposure in zebrafish - Dr Joana Viana, Research fellow, University of Exeter Medical School, UK
Workshop Schedule
Day 2 - Day 3
-Introduction to epigenetic epidemiology and study design
-Introduction to profiling methods, with specific focus on Illumina array
-Introduction to R
-QC of data using Exzweter pipeline (hands-on)
-Normalisation and basic analysis
-Problems in EWAS
-Interpreting results and pathway analysis
-Technologies for validating and confirming findings
Year(s) Of Engagement Activity 2019
URL https://epicon2019.wixsite.com/website
 
Description Mixed methods and qualitative research methods for understanding trauma-related mental health, October 25 - October 26, 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The School of Medicine conducted the workshop 'Mixed methods research and qualitative research applied to the understanding of trauma in Mental Health' , with guests from the University of Exeter, UK.
Its purpose was to analyze the use of various research tools such as qualitative methods: ethnography, grounded theory and thematic analysis; quantitative methods; mixed methods and multiple scanning.
Attendees were doctoral students, masters, psychiatries, psychologists and members of the Psychoanalytic Society, who took the intensive workshop Jorge Hoyos building (20), room 302.

PROGRAMME
Thursday 25 October
7.00 Welcome and Introduction
Dr. Carlos Gómez Restrepo, Decano Facultad de Medicina, Pontificia Universidad Javeriana, Colombia
7.30 - 8.00 Introduction to Research in Mental Health. A general overview. (Dr Anke Karl)
8.00 - 9.00 SESSION 1: Using qualitative research methods for studying mental health (Dr Janet Smithson, Dr Elizabeth Weightman).
Case studies:
• Ethnography/focus groups: Notions of home within an adolescent psychiatric inpatient unit (Smithson, J).
• An ethnographic investigation into psychoanalytic containment and whether it is provided by staff in an institution (Weightman, E.) .
• Service user involvement in PTSD research. Ex-patients interviewing patients (Weightman, E).
9.00 - 9.30 Discussion/activity in small groups.
9.30 - 10.00 Feed back and discussion.
10.00 - 10.30 Coffee break
10.30 - 11.30 SESSION 2: Combining qualitative and quantitative research in trauma and resilience after adversity (Dr Anke Karl).
Case studies:
• Why don't all trauma survivors develop post-traumatic stress disorder? A multi-method exploration of resilience.
• The relationship between self-compassion and Post Traumatic Stress Disorder.
• The role of self - compassion in mood repair for people with recurrent depression with and without experience of mindfulness.
• Thematic analysis/questionnaires: Associations between Posttraumatic Stress Disorder, Disclosure Ability and Gender Role Perceptions in Adult Survivors of Child Sexual Abuse.
11.45 - 12.30 Discussion/activity in small groups.
12.30 - 13.00 Feed back and Panel discussion.
13.00 - 14.00 Lunch
14.00 - 16.00 SESSION 3: Project Surgery: How to add a qualitative element to health research.
Smaller group. Participants will bring own projects to discuss.

Friday 26 October
8.00 - 9.00 SESSION 4: Considerations in cross-national research: challenges and opportunities (Dr Janet Smithson, Dr Anke Karl, Dr (C) Amelia Casas Pardo, Dr Elizabeth Weightman).
Case studies:
• Sibling relationships and their relevance to psychoanalytic work: a qualitative study (Casas Pardo, A.)
• European cross national research experiences (Smithson, J)
Cross cultural issues in trauma research (Karl, A).
• Cross cultural participant collaboration in research into the treatment of complex trauma (Weightman, E.).
9.00 - 9.30 Discussion/activity in small groups.
9.30 - 9.45 Feed back and discussion.
9.45 - 10.15 Coffee break
10.15 - 11.00 SESSION 5: Relevance and feasibility of the presented methods and case studies to the Colombian context, possibilities for collaboration. (Dr. Gómez Restrepo, with contribution from Smithson, Karl, Casas and Weightman).
11.00 - 11.30 Discussion/activity in small groups.
11.30 - 12.00 Closing Panel Discussion.
Year(s) Of Engagement Activity 2018
URL https://www.javeriana.edu.co/noticias/noticias?aID=10203744&tID=22767#.XIaS1qCnzIU
 
Description Networking meeting - LH 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Network meeting between the two PIs, Hogarth (Exeter) and Seedat (Stellenbosch) plus other researchers from LMIC countries, in London 29-30th September 2018
Year(s) Of Engagement Activity 2018
 
Description Plenary presentation at conference - LH 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact (African and Middle Eastern Congress on Addiction - South African Addiction Medicine Society joint meeting Cape Town, South Africa, 31 August to 1 September 2018. Presentation title: Sensitivity to distress-triggered drug-seeking drives vulnerability to drug dependence in individuals with psychiatric illness and trauma: Implications for targeted interventions.
Year(s) Of Engagement Activity 2018
 
Description Poster presention - LH 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Poster presented at the Society for the Study of Addiction conference in Newcastle 9th Nov 2018
Year(s) Of Engagement Activity 2018
URL https://www.addiction-ssa.org/symposium/invited/ssa-annual-conference-2018
 
Description Presentation at a workshop on habit and behaviour change at University of Ghent - LH 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at a workshop on habit and behaviour change at University of Ghent, 31st Nov 2018. Title of presentation: Drug addiction is a disorder of excessive goal-directed choice, not habit or compulsion.
Year(s) Of Engagement Activity 2006,2018
 
Description Research methods applied to the study of psychotherapy processes, 26 November 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact PROGRAMME:
1.30 - 2.00 Welcome and Introduction (Dr. Carlos Gómez Restrepo, Dr (C) Amelia Casas Pardo)
2.00 - 2.30 Research in mental health, a general overview (Dr. Anke Karl, Dr. Carlos Gómez)
2.30 - 3.15 Using "traditional" social science research methods for studying therapy processes: each method will be studied using case studies (worked examples) using the methodology.
1. The psychoanalytic focus: single case studies (Weightman, E).
2. Qualitative interview and focus group methods to understand the psychotherapy process (Smithson, J).
3. Narrative Analysis. Study of attachment narratives in therapy for depression (Smithson, J).
4. Discourse Analysis for researching the psychotherapy process (Smithson, J).
3.15 - 3.30 Break
3.30 - 4.15 Possibilities for developing psychoanalytic research methods
1. Developing a qualitative psychoanalytic research method: Challenges and opportunities (Dr Elizabeth Weightman).
2. Application of the Complex Intervention Framework and neuroscience to the study of psychoanalytic mechanisms and processes (Dr Anke Karl).
4.15-4.30 Break
4.30-5.00 Producing and publishing scientific articles: considering the specific challenges for qualitative, quantitative and psychoanalytic research (Dr Anke Karl, Dr Janet Smithson).
5.00 - 5.15 Questions and discussion
5.15 - 5.30 Closing remarks - Constanza Aranguren, Dr. Carlos Gómez Restrepo
Year(s) Of Engagement Activity 2018
 
Description South Africa workshop - Neuro disability and TBI 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact University of Cape Town & University of Exeter Joint Workshop. Neuro disability (including traumatic brain injuries) and trauma in adolescents in contact with the law: Findings and future studies
Year(s) Of Engagement Activity 2019
 
Description South African Research Chair PTSD meeting - LH 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact South African Research Chair PTSD meeting on 30th August
Year(s) Of Engagement Activity 2018
 
Description TRoPICA International Workshop 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact TRoPICA International Workshop - held at the Grange Fitzrovia Hotel, London from 29-30 September 2018.
Objectives of the meeting:
• To establish and consolidate a collaborative research network on pathways and mechanisms from early childhood trauma to heterogeneous mental health outcomes in Low- and Middle-Income Countries
• To identify research priorities for this network and lay out a plan for research to be conducted across the network
• To identify other potential partners to join the network

Outcomes
1. Participants presented outlines of their research and areas of overlap and common interest were identified.
2. Participants agreed to work together on several preliminary projects identified as priorities (a systematic review; analyses of a dataset Jamaican participants have access to from the Caribbean; source funding for pilot work with a view to developing a proposal for an international multisite study on early trauma and pathways to mental illness and substance abuse).
3. Identification of a researcher at the University of West Indies who will provide coordinating and administrative support to the group.
4. A Systematic Review of evidence relating to early childhood trauma and associations with mental illness and substance abuse outcomes in Low- and Middle-Income Countries.
This systematic review was registered with PROSPERO and is currently in progress and involves all partners - aim to submit for publication by June 2019.
Year(s) Of Engagement Activity 2018
 
Description Visit from Exeter PI's PhD student to South Africa PI's lab - LH 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Visit from Exeter PI's PhD student to South Africa (Stellenbosch) PI's lab 18-24th Feb 2019. The purpose is to write an ethics application for an intervention study at Stellenbosch.
Year(s) Of Engagement Activity 2019
 
Description Visit from South Africa Research Fellow to Exeter Lab - LH 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Visit from PI Seedat's Research Fellow to Hogarth's lab (Exeter) 11-13 Feb 2019. The purpose is to write an ethics application for an intervention study at Stellenbosch.
Year(s) Of Engagement Activity 2019
 
Description World Psychiatric Association Congress - Conference Paper - Understanding and building resilience to early life trauma in Belarus and Ukraine 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Objectives: To better understand the causes and impact of early life trauma (ELT) in Belarus and Ukraine, and to develop effective responses to this.
Background:ELT is a key determinant of later life health and wellbeing. Within Belarus and Ukraine, ELT has been associated with some of the highest levels of suicide and substance abuse amongst in the world. There is a dearth of detailed analysis of the causes of ELT in these countries, and little is known about the socio-cultural context in which it is experienced, understood and responded to.
Aim: To i) understand causes of ELT and the ways that multiple traumas interact to establish risk for negative mental health, substance abuse and suicide, and ii) identify the factors and mechanisms which promote resilience amongst those affected by ELT.
Materials and methods:This presentation will report on a series of cross-disciplinary/sector workshops focusing on the causes of early life trauma in Belarus and Ukraine; how traumas interact to establish risk for negative mental health; and the factors and mechanisms that promote resilience amongst those affected by ELT.
Results: Socio-cultural factors directly influence ELT in Belarus and Ukraine. A cross-disciplinary/sector approach enables important insights into public/patient understandings and experiences of ELT that will enable more effective responses and interventions from Mental health care systems.
Conclusions: Understanding the causes and impact of ELT and the socio-cultural context in which this takes place is necessary to provide effective mental health strategies and services in Belarus and Ukraine.
Year(s) Of Engagement Activity 2018,2019
URL http://earlylifetrauma.info/