Enhancing the MRC National Survey of Health and Development as an interdisciplinary life course study of ageing

Lead Research Organisation: MRC Unit for Lifelong Health and Ageing

Abstract

The greatest challenge for research on ageing is to ensure that the health and independence of older people keeps apace with their increasing life expectancy. Ageing starts at the beginning of life, and is affected by biological and social processes acting across the whole of life. This programme is concerned with scientific discovery of these processes. We conduct research on the MRC National Survey of Health and Development (NSHD), the oldest of the British birth cohorts. It is unique in having information, from birth to 66 years, on the health and social circumstances of a large representative sample of those born in England, Wales and Scotland in March 1946.
The focus of this programme is on enhancing the NSHD as a national resource by:
Collecting new data on ageing outcomes (www.nshd.mrc.ac.uk)
Undertaking collaborative research to study the factors at different life stages that promote or inhibit healthy ageing (see www.halcyon.ac.uk)
Encouraging the safe and secure use of NSHD resources, including the genetics resource, by the scientific community

Technical Summary

The MRC National Survey of Health and Development (NSHD) is the oldest of the British birth cohorts, and is unique in having data from birth to age 66 years on the health and social circumstances of a representative sample (N=5,362) of those born in England, Wales and Scotland in March 1946 (www.nshd.mrc.ac.uk). Enhancing NSHD is the core programme of the MRC Unit for Lifelong Health and Ageing, and combines a research and a resource function.

The resource function is to curate, enrich and share the NSHD resource, on which all Unit programmes and research collaborations depend. In the last five years, we have completed the 23rd follow-up, a pioneering clinic data collection, with a high response rate, developed data sharing policies and web-based data sharing tools, raised the international and national profile of the study through the NSHD 65th birthday events, and enhanced NSHD through new biomarker and genetic data. A critical mass of biomedical and social scientists undertakes collaborative projects; since 2007, NSHD data has been shared with 211 scientists from 49 research institutions.

The research function is to foster integrative research across the Unit programmes and with external collaborators, and to build capacity in life course epidemiology and ageing research. Ongoing studies include: the lifetime determinants of kidney function, thyroid function, and healthy ageing; the long-term health effects of exposure to air pollution; dietary studies; and genetic studies. Much of this work involves comparative research across cohorts. For example, LHA leads the Healthy Ageing across the Life Course (HALCyon) research programme which brings an interdisciplinary group of researchers to study life course determinants of three aspects of healthy ageing across nine UK cohort studies: physical and cognitive capability, social and psychological wellbeing and underlying biology, including aspects of physiology and genetics. More details can be found on www.halcyon.ac.uk.

The two main research themes for NSHD in the next five years are: (1) healthy ageing and the management of health and health care needs as the cohort grows older, and how these are influenced by earlier life experiences; and (2) the biology of ageing, linking epidemiology and mechanistic science in this cohort study. The latter includes planned metabolomic and epigenomic projects, and a new research collaboration on the ageing lung.
We also plan to extend HALCyon cross cohort research activities, data harmonisation and data sharing through our role in the new ESRC/MRC Cohort Resource Facility and through international collaborations.

Publications

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Almoosawi S (2012) Daily profiles of energy and nutrient intakes: are eating profiles changing over time? in European journal of clinical nutrition

 
Description Joining Forces in Mortality and Longevity
Geographic Reach National 
Policy Influence Type Participation in advisory committee
 
Description Marmot review on social inequalities in health
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
 
Description National Academy of Sciences working party on non experimental methods in biomedical research
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
 
Description Paper to Royal College of Obstetricians and Gynaecologists Scientific Advisory committee
Geographic Reach National 
Policy Influence Type Citation in other policy documents
 
Description The Dutch Famine Society
Geographic Reach Europe 
Policy Influence Type Participation in advisory committee
 
Description ESRC Network 'GENET' and other small ESRC grants
Amount £20,366 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 04/2006 
End 03/2009
 
Description ESRC, NDA Seedcorn grant
Amount £20,000 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 09/2006 
End 09/2007
 
Description European Association for the Study of Obesity Travel Award
Amount € 500 (EUR)
Organisation European Association for the Study of Obesity 
Sector Charity/Non Profit
Country European Union (EU)
Start  
 
Description FP7 (partner) ESCAPE
Amount £37,262 (GBP)
Funding ID 211250 
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start 05/2008 
End 04/2012
 
Description IALSA/Canadian Institute of Health Research
Amount £137,800 (GBP)
Organisation Canadian Institutes of Health Research 
Sector Public
Country Canada
Start 09/2010 
End 08/2012
 
Description KRUK project grant - 'life course influences on kidney function'
Amount £72,418 (GBP)
Organisation Kidney Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2010 
End 03/2012
 
Description Lifelong Health and Wellbeing Initiative grant. The menopausal transition and healthy ageing and wellbeing
Amount £1,502,930 (GBP)
Funding ID G1001357 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC Biomarkers Call
Amount £81,384 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2007 
End 03/2011
 
Description MRC Centenary Awards
Amount £45,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Managing the menopause: women's experiences and primary care practice
Amount £241,780 (GBP)
Funding ID PB-PG-0407-13293 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 10/2008 
End 04/2011
 
Description RES-353-25-0001 HALCyon Healthy Ageing across the Life Course (New Dynamics of Ageing) £1.4m shared with G Davey Smith, D Kuh and I Deary
Amount £452,955 (GBP)
Funding ID ES/G00773X/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 09/2008 
End 03/2013
 
Description Research for patient benefit programme - 'Managing the menopause'
Amount £2,500 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 12/2010
 
Description UCLEB Consortium of population based studies
Amount £970,230 (GBP)
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description US National Institure on Ageing (NIA), Life course fellowship
Amount £45,410 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Title 60-64 Biological Samples 
Description 60-64 Urine, saliva and blood samples. Telomere data IGF Testosterone Cortisol Biomarkers 
Type Of Material Biological samples 
Year Produced 2012 
Provided To Others? Yes  
Impact too early to say - data is available for researchers to use 
 
Title 60-64 Cardio-respiratory fitness measures 
Description Heart rate response to an incremental step test 
Type Of Material Biological samples 
Year Produced 2012 
Provided To Others? Yes  
Impact too early to say - data is available for researchers to use 
 
Title 60-64 Cardiovascular measures 
Description Measures of Vascular structure and function: carotid intima-medial thickness (IMT) and arterial distensibility (GE Vivid-I), carotid/femoral pulse wave velocity (Vicorder) and central blood pressure and pulse wave analysis (Sphygmocor) Cardiac structure and function: echocardiography (GE Vivid-I). Images from parasternal long axis and short axis views, apical 5-chamber, 4-chamber, 3-chamber, 2-chamber and aortic views (plus conventional and tissue Doppler in 4-chamber view). Brachial blood pressure (Omron HEM-705), 12 lead ECG (Burdick Eclipse 850i), including 6 minute heart rate and respiration recordings by ECG for heart rate variability measurements. Antihypertensive medication by postal questionnaire 
Type Of Material Biological samples 
Year Produced 2012 
Provided To Others? Yes  
Impact too early to say - data is available for researchers to use 
 
Title 60-64 Free-living physical activity measures 
Description Five continuous days by combined heart rate and movement sensor (Actiheart) with individual calibration. Self reported physical capability 
Type Of Material Biological samples 
Year Produced 2012 
Provided To Others? Yes  
Impact too early to say - data is available for researchers to use 
 
Title 60-64 Functional capacity, biological function, and anthropometric measures 
Description Verbal memory, search speed and concentration, simple and choice reaction time, standing balance, grip strength, chair rises, get up and go test, spirometry Standing and sitting height, weight, chest, upper arm, waist & hip circumference. 
Type Of Material Biological samples 
Year Produced 2012 
Provided To Others? Yes  
Impact too early to say - data is available for researchers to use 
 
Title 60-64 HNR Dietary data 
Description New dietary data collected at 60-64 years on NSHD - dataset now available Daily food group Alcohol Nutrients 
Type Of Material Biological samples 
Year Produced 2011 
Provided To Others? Yes  
Impact too soon to tell, hoping to maximise potential use of NSHD dietary data 
 
Title 60-64 Musculoskeletal assessment 
Description Measures of DXA (QDR 4500 Discovery): Hip (total, femoral neck, trochanter, Ward's), lumbar spine (L1-4), whole body & region BMD, fat & lean mass, vertebral fracture assessment, aortic calcification score pQCT (Stratec XCT 2000) radius: 4% site(trabecular, cortical and subcortical BMD), 50% site (endosteal/periosteal circumference, cortical CS area & thickness, BMC & BMD, CS muscle & fat area, stress strain index, moment of inertia) Osteoporosis medication by postal questionnaire Fracture data 
Type Of Material Biological samples 
Year Produced 2012 
Provided To Others? Yes  
Impact too early to say - data is available for researchers to use 
 
Title 60-64 Other data collected 
Description Rose angina, intermittent claudication, bronchitis, chest pain, lung function, blood pressure, doctor diagnosed CVD events and test for chest pain/heart disease, osteoarthritis symptoms, back pain, knee injuries, functional limitations, fracture history, prescribed and non-prescribed regular medication, hospital admissions, day surgery, outpatients. FIts/epilepsy Supplements Dietary and alcohol assessment (5-day diary), CAGE, physical activity assessment (EPAQ2), Household income and sources, perceived financial hardship, periods of unemployment, household size and housing tenure, own/partner's occupation, retirement class and work status. Household size Neighbourhood Frailty Marriage status Number of Children/Grandchildren Number of clinical disorders Smoking Consent Contact/response Status HRT/Menopause 
Type Of Material Biological samples 
Year Produced 2012 
Provided To Others? Yes  
Impact too early to say - data is available for researchers to use 
 
Title 60-64 Questionnaires 
Description Postal questionnaire Nurse Schedule Pre- assessment questionnaire Self completion questionnarie Paper Test Women's Health Questionnaire 
Type Of Material Biological samples 
Year Produced 2013 
Provided To Others? Yes  
Impact data is being shared with other scientists for analysis 
 
Title 60-64 Wellbeing Measures 
Description GHQ28, the Close Person Questionnaire, life events, SF36, Edinburgh wellbeing scale, life satisfaction, neighbourhood satisfaction, spare time activities, parental death, time spent caring for others, updated marital and fertility histories 
Type Of Material Biological samples 
Year Produced 2013 
Provided To Others? Yes  
Impact Available to other researchers to use 
 
Title NSHD DNA repository 
Description In 2007-8 NSHD DNA samples were transferred to Gene Services, MREC approval was received for genetic studies of lifelong health and ageing, and policies and procedures for governance and sharing of samples were put in place 
Type Of Material Biological samples 
Year Produced 2007 
Provided To Others? Yes  
Impact genetic outputs are listed in publications and collaborations 
 
Title NSHD clinic data collection 
Description The NSHD clinical data collection is now complete Specialist databases now ready for scientific use: IMT, Pulsewave Velocity, ECG, DXA and pQRT, Actiheart, Cardiac dataset, dietary dataset, blood sample database 
Type Of Material Biological samples 
Year Produced 2009 
Provided To Others? Yes  
Impact Forthcoming publications 
 
Title NSHD data archive 
Description The archive holds electronic data and paper records from the start of the MRC NSHD in 1946. There are numerous variables collected during different data collections. 
Type Of Material Biological samples 
Provided To Others? Yes  
Impact numerous publications 
 
Title NSHD job and occupational histories dataset 
Description With the Centre for Longitudinal Studies and funded by the GENET ESRC network, we have created a new NSHD dataset of derived variables describing NSHD job and occupational histories from 16-53 years 
Type Of Material Biological samples 
Year Produced 2009 
Provided To Others? Yes  
Impact The dataset has only just been added to the NSHD archive and is currently being advertised to other researchers 
 
Title SWIFT (Secure Web Based Infrastructure for the NSHD) 
Description SWIFT is a web based data discovery and data sharing tool which includes a 'Google' - like search engine and the governance processes needed for data sharing. MRCT is currently advising on copyright 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact Plan to provide tool to other research groups through Data Support Service. Tool is just completing external testing and the transition to service phase takes place in 2010. It will allow NSHD data discovery and data downloading for approved projects using remote access. The impact could be considerable for maximising research potential of NSHD and other MRC cohort studies 
 
Title 60-64 Medication information 
Description Medication information from study members collected during 2006-2010 includes 
Type Of Material Database/Collection of data 
Year Produced 2013 
Provided To Others? Yes  
Impact too early to tell - hopefully increased used of the data from NSHD which will lead to impacts 
 
Description ADH1B-cardiovascular disease collaboration 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution NSHD data sharing (genotyping already completed) Contribute to the scientific development of the project throughout Help with drafting and revision of papers
Collaborator Contribution Analysis and interpretation of data Preparation of manuscripts
Impact Holmes et al PMID: 25011450
Start Year 2012
 
Description Ageing Lung consortium 
Organisation Imperial College London
Department Faculty of Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution To test (1) whether the social and biological factors operating early in life, and previously found in this cohort to adversely influence adult lung function and respiratory symptoms, also affect decline in lung function with age; (2) whether cumulative exposure to an anti-oxidant rich diet is associated with slower lung function decline; (3) whether these effects are mediated through altered DNA methylation; (4) whether DNA methylation signatures predict which smokers will have accelerated decline; and (5) whether the associations between lung function and mortality, cardiovascular disease and diabetes might be explained by patterns of early growth or later diet, by perturbation of inflammatory/hormonal pathways, or by genes. Longer-term plans: To add a more detailed assessment of lung function and respiratory disease at the next follow-up in order to define COPD and its sub-phenotypes better. NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Analysis, interpretation, drafting and revision of papers. At the next data collection, our expert collaborators, will help LHA to characterise lung function and its decline and the development of respiratory disease in greater detail. One collaborator will jointly supervise a new CDF post who will investigate lung function decline.
Impact A grant application has been written and is in the process of being submitted Dunhill Medical Trust grant application invited to full application stage - Seif Shaheen Horsfall et al PMID: 25086287 PMID 26695373
Start Year 2012
 
Description Ageing Lung consortium 
Organisation Medical Research Council (MRC)
Department MRC Human Nutrition Research Unit
Country United Kingdom 
Sector Public 
PI Contribution To test (1) whether the social and biological factors operating early in life, and previously found in this cohort to adversely influence adult lung function and respiratory symptoms, also affect decline in lung function with age; (2) whether cumulative exposure to an anti-oxidant rich diet is associated with slower lung function decline; (3) whether these effects are mediated through altered DNA methylation; (4) whether DNA methylation signatures predict which smokers will have accelerated decline; and (5) whether the associations between lung function and mortality, cardiovascular disease and diabetes might be explained by patterns of early growth or later diet, by perturbation of inflammatory/hormonal pathways, or by genes. Longer-term plans: To add a more detailed assessment of lung function and respiratory disease at the next follow-up in order to define COPD and its sub-phenotypes better. NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Analysis, interpretation, drafting and revision of papers. At the next data collection, our expert collaborators, will help LHA to characterise lung function and its decline and the development of respiratory disease in greater detail. One collaborator will jointly supervise a new CDF post who will investigate lung function decline.
Impact A grant application has been written and is in the process of being submitted Dunhill Medical Trust grant application invited to full application stage - Seif Shaheen Horsfall et al PMID: 25086287 PMID 26695373
Start Year 2012
 
Description Ageing Lung consortium 
Organisation Queen Mary University of London
Department Barts and The London School of Medicine and Dentistry
Country United Kingdom 
Sector Academic/University 
PI Contribution To test (1) whether the social and biological factors operating early in life, and previously found in this cohort to adversely influence adult lung function and respiratory symptoms, also affect decline in lung function with age; (2) whether cumulative exposure to an anti-oxidant rich diet is associated with slower lung function decline; (3) whether these effects are mediated through altered DNA methylation; (4) whether DNA methylation signatures predict which smokers will have accelerated decline; and (5) whether the associations between lung function and mortality, cardiovascular disease and diabetes might be explained by patterns of early growth or later diet, by perturbation of inflammatory/hormonal pathways, or by genes. Longer-term plans: To add a more detailed assessment of lung function and respiratory disease at the next follow-up in order to define COPD and its sub-phenotypes better. NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Analysis, interpretation, drafting and revision of papers. At the next data collection, our expert collaborators, will help LHA to characterise lung function and its decline and the development of respiratory disease in greater detail. One collaborator will jointly supervise a new CDF post who will investigate lung function decline.
Impact A grant application has been written and is in the process of being submitted Dunhill Medical Trust grant application invited to full application stage - Seif Shaheen Horsfall et al PMID: 25086287 PMID 26695373
Start Year 2012
 
Description Ageing Lung consortium 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution To test (1) whether the social and biological factors operating early in life, and previously found in this cohort to adversely influence adult lung function and respiratory symptoms, also affect decline in lung function with age; (2) whether cumulative exposure to an anti-oxidant rich diet is associated with slower lung function decline; (3) whether these effects are mediated through altered DNA methylation; (4) whether DNA methylation signatures predict which smokers will have accelerated decline; and (5) whether the associations between lung function and mortality, cardiovascular disease and diabetes might be explained by patterns of early growth or later diet, by perturbation of inflammatory/hormonal pathways, or by genes. Longer-term plans: To add a more detailed assessment of lung function and respiratory disease at the next follow-up in order to define COPD and its sub-phenotypes better. NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Analysis, interpretation, drafting and revision of papers. At the next data collection, our expert collaborators, will help LHA to characterise lung function and its decline and the development of respiratory disease in greater detail. One collaborator will jointly supervise a new CDF post who will investigate lung function decline.
Impact A grant application has been written and is in the process of being submitted Dunhill Medical Trust grant application invited to full application stage - Seif Shaheen Horsfall et al PMID: 25086287 PMID 26695373
Start Year 2012
 
Description Ageing Lung consortium 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution To test (1) whether the social and biological factors operating early in life, and previously found in this cohort to adversely influence adult lung function and respiratory symptoms, also affect decline in lung function with age; (2) whether cumulative exposure to an anti-oxidant rich diet is associated with slower lung function decline; (3) whether these effects are mediated through altered DNA methylation; (4) whether DNA methylation signatures predict which smokers will have accelerated decline; and (5) whether the associations between lung function and mortality, cardiovascular disease and diabetes might be explained by patterns of early growth or later diet, by perturbation of inflammatory/hormonal pathways, or by genes. Longer-term plans: To add a more detailed assessment of lung function and respiratory disease at the next follow-up in order to define COPD and its sub-phenotypes better. NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Analysis, interpretation, drafting and revision of papers. At the next data collection, our expert collaborators, will help LHA to characterise lung function and its decline and the development of respiratory disease in greater detail. One collaborator will jointly supervise a new CDF post who will investigate lung function decline.
Impact A grant application has been written and is in the process of being submitted Dunhill Medical Trust grant application invited to full application stage - Seif Shaheen Horsfall et al PMID: 25086287 PMID 26695373
Start Year 2012
 
Description Biomarkers of Ageing 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution We have shared NSHD DNA data and LHA scientists are leading and contributing to scientific outputs
Collaborator Contribution LHA scientists are gaining knowledge about telomeres and other markers of biological ageing
Impact Enriching the NSHD with new data on telomeres. Scientific outputs are forthcoming I have extended the collaboration between LHA and the Institute of Ageing by asking Professor Thomas Zyglinicki to be a work package leader on a telomere study across a number of cohorts as part of the HALCyon research programme on which I am the PI. Baylis et al PMID:24858709 Martin-Ruiz et al PMID: 25239152 PMID 26403813 PMID 26403811 PMID 25239152
Start Year 2007
 
Description CAPA 
Organisation Alzheimer's Drug Discovery Foundation
Country United States 
Sector Charity/Non Profit 
PI Contribution The ADDF created the Cohorts for Alzheimer's Prevention Action (CAPA) Consortium to strengthen the evidence for potential preventative treatments. This program will fund specific analyses across a minimum of 5 longitudinal cohorts to examine the association of actionable interventions with the risk of cognitive aging, Alzheimer's disease, related dementias, or biomarkers related to brain aging and neurodegeneration. NSHD will apply for specific funding to use NSHD data to help find interventions in relation to Alzheimer's disease, related dementias, or biomarkers related to brain aging and neurodegeneration.
Collaborator Contribution Funding will be provided
Impact We have only just joined this consortium so are looking at ways to become involved
Start Year 2014
 
Description Collaboration on life course theory and methods 
Organisation King's College London
Department Institute of Psychiatry, Psychology & Neuroscience
Country United Kingdom 
Sector Academic/University 
PI Contribution Scientific leads on study design and drafting manuscripts vary, often involves data sharing, always analysis, interpretation and revision of manuscripts
Collaborator Contribution co-editing book on life course methodscollaboration on statistical life course methodscollaboration on statistical life course theory and methodsjoint drafting and revising manuscripts
Impact methods book and chapters 16306313 De Stavola et al AJE 2006 19028777 Mishra GD, Ben-Shlomo Y, Kuh D (in press) Life course approach to health behaviors: theory and methods. In Eds A. Steptoe et al. Handbook of Behavioral Medicine: Methods and Applications. Springer Power and Kuh 2006 Life course development of unequal health. In J Siegrist, M Marmot (Eds) Socioeconomic position and health: new explanations and their policy implications. Oxford University Press SMILE II grant application was not funded Ben Shlomo IJE review PMID: 27880685 Tilling PMID:27880690 Use and misuse of life course methods Howe PMID: 27681097 Mediation analysis and structured life course approach Smith PMID: 27371628 A structure approach to hypotheses
Start Year 2006
 
Description Collaboration on life course theory and methods 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Scientific leads on study design and drafting manuscripts vary, often involves data sharing, always analysis, interpretation and revision of manuscripts
Collaborator Contribution co-editing book on life course methodscollaboration on statistical life course methodscollaboration on statistical life course theory and methodsjoint drafting and revising manuscripts
Impact methods book and chapters 16306313 De Stavola et al AJE 2006 19028777 Mishra GD, Ben-Shlomo Y, Kuh D (in press) Life course approach to health behaviors: theory and methods. In Eds A. Steptoe et al. Handbook of Behavioral Medicine: Methods and Applications. Springer Power and Kuh 2006 Life course development of unequal health. In J Siegrist, M Marmot (Eds) Socioeconomic position and health: new explanations and their policy implications. Oxford University Press SMILE II grant application was not funded Ben Shlomo IJE review PMID: 27880685 Tilling PMID:27880690 Use and misuse of life course methods Howe PMID: 27681097 Mediation analysis and structured life course approach Smith PMID: 27371628 A structure approach to hypotheses
Start Year 2006
 
Description Collaboration on life course theory and methods 
Organisation University College London
Department Institute of Child Health
Country United Kingdom 
Sector Academic/University 
PI Contribution Scientific leads on study design and drafting manuscripts vary, often involves data sharing, always analysis, interpretation and revision of manuscripts
Collaborator Contribution co-editing book on life course methodscollaboration on statistical life course methodscollaboration on statistical life course theory and methodsjoint drafting and revising manuscripts
Impact methods book and chapters 16306313 De Stavola et al AJE 2006 19028777 Mishra GD, Ben-Shlomo Y, Kuh D (in press) Life course approach to health behaviors: theory and methods. In Eds A. Steptoe et al. Handbook of Behavioral Medicine: Methods and Applications. Springer Power and Kuh 2006 Life course development of unequal health. In J Siegrist, M Marmot (Eds) Socioeconomic position and health: new explanations and their policy implications. Oxford University Press SMILE II grant application was not funded Ben Shlomo IJE review PMID: 27880685 Tilling PMID:27880690 Use and misuse of life course methods Howe PMID: 27681097 Mediation analysis and structured life course approach Smith PMID: 27371628 A structure approach to hypotheses
Start Year 2006
 
Description Collaboration on life course theory and methods 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Scientific leads on study design and drafting manuscripts vary, often involves data sharing, always analysis, interpretation and revision of manuscripts
Collaborator Contribution co-editing book on life course methodscollaboration on statistical life course methodscollaboration on statistical life course theory and methodsjoint drafting and revising manuscripts
Impact methods book and chapters 16306313 De Stavola et al AJE 2006 19028777 Mishra GD, Ben-Shlomo Y, Kuh D (in press) Life course approach to health behaviors: theory and methods. In Eds A. Steptoe et al. Handbook of Behavioral Medicine: Methods and Applications. Springer Power and Kuh 2006 Life course development of unequal health. In J Siegrist, M Marmot (Eds) Socioeconomic position and health: new explanations and their policy implications. Oxford University Press SMILE II grant application was not funded Ben Shlomo IJE review PMID: 27880685 Tilling PMID:27880690 Use and misuse of life course methods Howe PMID: 27681097 Mediation analysis and structured life course approach Smith PMID: 27371628 A structure approach to hypotheses
Start Year 2006
 
Description Collaboration on life course theory and methods 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution Scientific leads on study design and drafting manuscripts vary, often involves data sharing, always analysis, interpretation and revision of manuscripts
Collaborator Contribution co-editing book on life course methodscollaboration on statistical life course methodscollaboration on statistical life course theory and methodsjoint drafting and revising manuscripts
Impact methods book and chapters 16306313 De Stavola et al AJE 2006 19028777 Mishra GD, Ben-Shlomo Y, Kuh D (in press) Life course approach to health behaviors: theory and methods. In Eds A. Steptoe et al. Handbook of Behavioral Medicine: Methods and Applications. Springer Power and Kuh 2006 Life course development of unequal health. In J Siegrist, M Marmot (Eds) Socioeconomic position and health: new explanations and their policy implications. Oxford University Press SMILE II grant application was not funded Ben Shlomo IJE review PMID: 27880685 Tilling PMID:27880690 Use and misuse of life course methods Howe PMID: 27681097 Mediation analysis and structured life course approach Smith PMID: 27371628 A structure approach to hypotheses
Start Year 2006
 
Description Collaboration with HNR 
Organisation Medical Research Council (MRC)
Department MRC Human Nutrition Research Unit
Country United Kingdom 
Sector Public 
PI Contribution NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Analysis, interpretation, drafting and revision of papers Storage of some biological samples
Impact Grant on Nutrition through the lifecourse submitted Heraclides et al PMID: 21877233 Mulla et al PMID: 22923606 Pot et al PMID:24477178 Pot et al PMID:24675713 Pot PMID: 25351642 Pot PMID: 26548599 Pastorino PMID:27245103 Maddock, J, Ziauddeen, N, Ambrosini, GL, Wong, A, Hardy, R, Ray S. Is there a relationship between adherence to a DASH-type diet and vascular function in the 1946 British birth cohort. British Journal of Nutrition. In press. Maddock paper PMID: 30005901 Maddock paper PMID: 29508688 Sanders paper PMID: 29925420
Start Year 2008
 
Description Collaboration with TC Institute of Child Health 
Organisation University College London
Department Institute of Child Health
Country United Kingdom 
Sector Academic/University 
PI Contribution We are collaborating on a recently obtained grant developing and applying the SITAR method of growth curve analysis for translational exposures and life course outcomes in human growth assessment. We initially plan to relate the derived parameters to genetic obesity-risk-allele scores and subsequently to health outcomes. Providing NSHD data and expertise
Collaborator Contribution Data analysis, interpretation, drafting and revision of papers. Providing methodological expertise.
Impact Funding for grant application - Developing and applying the SITAR method of growth curve analysis for translational exposures and life course outcomes in human growth assessment. Cole: PMID:27466311 Using SITAR to relate pubertal growth to bone health in later life: the MRC National Survey of Health and Development Kuh: PMID: 27401728 Puberty and bone paper. Variables derived as part of this collaboration are still being used in analysis
Start Year 2012
 
Description Collaboration with UCL Department of Statistical Science 
Organisation University College London
Department Department of Statistical Science
Country United Kingdom 
Sector Academic/University 
PI Contribution One of our new Programme Leader Tracks collaborates with another researcher in the Department of Statistical Science. The CDF used to work with this PI at Cambridge and this collaboration has continued since moving to the Unit. Contributions include data analysis, publication writing, grant applications and editing manuscripts.
Collaborator Contribution Contributions include data analysis, publication writing, grant applications and editing manuscripts.
Impact Grant application 'Optimal design parameters for individual change point models in dementia and ageing research' submitted Publications 23471297 23276221 23136147 PI on grant submitted. Optimal design parameters for individual change point models in dementia and ageing research. Submitted to MRC methodology Board. Co-Pi on grant not funded after first attempt. Analysing cognitive function in the older population: joint latent class models for change and survival. Submitted to MRC methodology board
Start Year 2013
 
Description Collaborations on genetics NES 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Prof Aroon Hingorani Expertise in genetics of respiratory functionexpertise in genetics and respiratory function Dallas Swallow provides expertise from UCL Research Department of Genetics, Evolution and Environment
Impact 19254294 Black et al 16759176 Rousseau et al 23551418 Johnson et al 25086287 Horsfall et al
Start Year 2006
 
Description Collaborations on genetics NES 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Prof Aroon Hingorani Expertise in genetics of respiratory functionexpertise in genetics and respiratory function Dallas Swallow provides expertise from UCL Research Department of Genetics, Evolution and Environment
Impact 19254294 Black et al 16759176 Rousseau et al 23551418 Johnson et al 25086287 Horsfall et al
Start Year 2006
 
Description Collaborations on genetics NES 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Prof Aroon Hingorani Expertise in genetics of respiratory functionexpertise in genetics and respiratory function Dallas Swallow provides expertise from UCL Research Department of Genetics, Evolution and Environment
Impact 19254294 Black et al 16759176 Rousseau et al 23551418 Johnson et al 25086287 Horsfall et al
Start Year 2006
 
Description Describing habitual levels of physical activity LLHW Bristol Collaboration 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Contribtion to grant application ' Describing habitual levels of physical activity in older people in terms of impact loads and how this relates to bone and other systems' that was funded by LLHW
Collaborator Contribution Contribtion to grant application ' Describing habitual levels of physical activity in older people in terms of impact loads and how this relates to bone and other systems' that was funded by LLHW
Impact Grant application awarded in 2013 Protocols have been drafted (2014) Data collection will be incorporated in to 2015 NSHD home visit Around 800 NSHD study members have worn an accelerometer and 1900 have completed an activity questionnaire; these data are comparable to those collected in 3 other studies participating in VIBE. Hannan PMID:27798733 Gaysin T. Physical activity producing low, but not medium or higher, vertical impacts is inversely related to BMI in older adults: findings from a multi cohort study. PMID:29028919 Elhakeem A. Associations of lifetime walking and weight bearing exercise with high impact physical activity in later life. PMID: 29134173 PMC5671612 Elhakeem A. Correlates of high impact physical activity measured objectively in older British adults. PMID: 29237047
Start Year 2012
 
Description Endocrine Senescence collaboration 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution (1) To relate IGF-1 and testosterone, cross-sectionally and longitudinally, to measures of bone and muscle mass, osteoporosis and sarcopenia, and physical and cognitive performance, and (2) to assess whether these hormones are stronger predictors of these ageing outcomes when used together, or in combination with measures of cortisol regulation and thyroid function. Longer-term plans: To undertake a cross cohort study to examine the role of IGF-1 for maintaining healthy trajectories of physical capability. NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Writing grant applications, joint scientific leads on study design and drafting manuscripts, student supervision analysis, interpretation and revision of manuscripts.
Impact A grant application was written for this collaboration. Numerous biological assays including IGF have been funded and will be completed by our collaborators by March 2013. A CDF post starting in January 2013 will be jointly supervised by one of these collaborators. Two papers are in progress Two papers have been revised and resubmitted - Testosterone and body composition and IGF and obesity PMID 25645314,25875330,26053924,26588434
Start Year 2012
 
Description Endocrine Senescence collaboration 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution (1) To relate IGF-1 and testosterone, cross-sectionally and longitudinally, to measures of bone and muscle mass, osteoporosis and sarcopenia, and physical and cognitive performance, and (2) to assess whether these hormones are stronger predictors of these ageing outcomes when used together, or in combination with measures of cortisol regulation and thyroid function. Longer-term plans: To undertake a cross cohort study to examine the role of IGF-1 for maintaining healthy trajectories of physical capability. NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Writing grant applications, joint scientific leads on study design and drafting manuscripts, student supervision analysis, interpretation and revision of manuscripts.
Impact A grant application was written for this collaboration. Numerous biological assays including IGF have been funded and will be completed by our collaborators by March 2013. A CDF post starting in January 2013 will be jointly supervised by one of these collaborators. Two papers are in progress Two papers have been revised and resubmitted - Testosterone and body composition and IGF and obesity PMID 25645314,25875330,26053924,26588434
Start Year 2012
 
Description Endocrine Senescence collaboration 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution (1) To relate IGF-1 and testosterone, cross-sectionally and longitudinally, to measures of bone and muscle mass, osteoporosis and sarcopenia, and physical and cognitive performance, and (2) to assess whether these hormones are stronger predictors of these ageing outcomes when used together, or in combination with measures of cortisol regulation and thyroid function. Longer-term plans: To undertake a cross cohort study to examine the role of IGF-1 for maintaining healthy trajectories of physical capability. NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Writing grant applications, joint scientific leads on study design and drafting manuscripts, student supervision analysis, interpretation and revision of manuscripts.
Impact A grant application was written for this collaboration. Numerous biological assays including IGF have been funded and will be completed by our collaborators by March 2013. A CDF post starting in January 2013 will be jointly supervised by one of these collaborators. Two papers are in progress Two papers have been revised and resubmitted - Testosterone and body composition and IGF and obesity PMID 25645314,25875330,26053924,26588434
Start Year 2012
 
Description Endocrine Senescence collaboration 
Organisation University of Southampton
Department MRC Lifecourse Epidemiology Unit
Country United Kingdom 
Sector Public 
PI Contribution (1) To relate IGF-1 and testosterone, cross-sectionally and longitudinally, to measures of bone and muscle mass, osteoporosis and sarcopenia, and physical and cognitive performance, and (2) to assess whether these hormones are stronger predictors of these ageing outcomes when used together, or in combination with measures of cortisol regulation and thyroid function. Longer-term plans: To undertake a cross cohort study to examine the role of IGF-1 for maintaining healthy trajectories of physical capability. NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Writing grant applications, joint scientific leads on study design and drafting manuscripts, student supervision analysis, interpretation and revision of manuscripts.
Impact A grant application was written for this collaboration. Numerous biological assays including IGF have been funded and will be completed by our collaborators by March 2013. A CDF post starting in January 2013 will be jointly supervised by one of these collaborators. Two papers are in progress Two papers have been revised and resubmitted - Testosterone and body composition and IGF and obesity PMID 25645314,25875330,26053924,26588434
Start Year 2012
 
Description GWAS - ID Bristol 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution In the well established set of cohorts participating in the Halcyon consortium, our collaborators in Bristol will extend their ongoing molecular genetic studies of specific gene targets, to GWAS.
Impact Grant application has been submitted to MRC
Start Year 2012
 
Description GWAS - ID Bristol 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution In the well established set of cohorts participating in the Halcyon consortium, our collaborators in Bristol will extend their ongoing molecular genetic studies of specific gene targets, to GWAS.
Impact Grant application has been submitted to MRC
Start Year 2012
 
Description GWAS - ID Bristol 
Organisation University of Southampton
Department MRC Lifecourse Epidemiology Unit
Country United Kingdom 
Sector Public 
PI Contribution NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution In the well established set of cohorts participating in the Halcyon consortium, our collaborators in Bristol will extend their ongoing molecular genetic studies of specific gene targets, to GWAS.
Impact Grant application has been submitted to MRC
Start Year 2012
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation McGill University
Country Canada 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation Medical Research Council (MRC)
Department MRC Human Nutrition Research Unit
Country United Kingdom 
Sector Public 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation National Institute on Aging
Country United States 
Sector Public 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation University College London
Department Institute of Child Health
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation University of Cambridge
Department MRC Epidemiology Unit
Country United Kingdom 
Sector Multiple 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation University of London
Department Institute of Education
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Healthy Ageing Across the Life course (HALCyon) 
Organisation University of Portsmouth
Country United Kingdom 
Sector Academic/University 
PI Contribution Diana Kuh is the PI of this interdisciplinary collaboration of scientists investigating the life course determinants of healthy ageing in 9 UK cohort studies. Rebecca Hardy leads the methodological core and the capability work package. Marcus Richards leads the knowledge transfer component and co-leads the nutritional work package. Gita Mishra is a member of the nutritional and wellbeing work packages. 2 postdoctoral scientists are HALCyon-funded.
Collaborator Contribution Yoav Ben-Shlomo in Bristol leads on the biology of ageing work packages for HALCyon, provides cohort data.Prof Thomas Zyglinivki leads the corss cohort HALCyon work package on telomeresProf Avan Aihie Sayer contributes to the HALCyon capability work package. Dr Catherine Gale leads the HALCyon wellbeing work package. Prof Cyrus Cooper is a co-investigator. Provide cohort data.HALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorCo-lead of HALCyon nutrition work packageHALCyon co-investigator for geocodingHALCyon co-investigator provides Lothian cohort dataHALCyon co-investigatorHALCyon co-investigatorHALCyon co-investigatorExpertise in geriatric medicine and frailtyExpertise on ageing
Impact Several workshops and publications. Symposium - April 2010 Conference - Nov 2010 Conference- June 2012 Workshop - September 2012 Numerous published papers have used the data from other cohorts and other researcher have contributed to the production of these research papers. Data sent to external scientists 2016 21542061 21332924 21297868 22114723 20843964 22253814 23072920 22970320 22923606 22658392 22326597 22209408 21349224 21764771 21737047 21860018 20829298 20843964 19864640 23108707 21225350 22415954 21416275 22923606 17634317 20214846 23468552 23072920 23894584 23818103 22658392 23922731 23437142 Kuh et al: A life course approach to physical capability: findings from the HALCyon research programme. Bode and Scheidt-Nave (eds): European Workshop on Health and Disability Surveillance in Ageing Populations (EUWAP). BMC Proceedings 2013, Volume 7, Supplement 4:S4 BMC Proceedings 2013, 7(Suppl 4):S4. Alfred et al PMID:25073452 Cooper et al PMID:23818103 Elliott et al PMID: 24602970 Gardner 24365661 North 26671949 North 26831755 HALCyon Plain English Summary Brochure produced NDA findings brochure produced OUP book published - A life course approach to healthy ageing Production of meta-data and datasets https://discover.ukdataservice.ac.uk/catalogue/?sn=851494&type=Data%20catalogue One application approved for data sharing
Start Year 2008
 
Description Hip and spine morphologies - Aberdeen Collaboration 
Organisation Manchester University NHS Foundation Trust
Country United Kingdom 
Sector Public 
PI Contribution Collboration to look at hip and spine morphologies in the NSHD. The unit will provide the study members for the project, help with coordination of the project, data analysis, creation and editing of manuscripts and writing grant applications.
Collaborator Contribution Coordination of the project, data analysis, creation and editing of manuscripts and writing grant applications.
Impact A grant application has been awarded by the MRC - November 2013 Aberdeen have finished deriving a complete dataset of hip shape mode scores and one on spine shape is due to be delivered soon. Conference abstracts have been submitted by the Aberdeen group LHA is now planning analyses that will be led by them Muthuri and Pavlova submitted papers abstracts submitted Muthuri SG.Associations between body mass index across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort.PMID:28842363 PMC5658512 Pavlova AV. Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development.PMID:28561274 PMC5522893 Ireland A, Saunders FR, Muthuri SG, Pavlova AV, Hardy RJ, Martin KR, Barr RJ, Adams JE, Kuh D, Aspden RM, Gregory JS, Cooper R. Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age. J Bone Miner Res. 2018 Nov 29. doi: 10.1002/jbmr.3627. [Epub ahead of print] PMID: 30496618. Muthuri SG, Pavlova AV, Saunders FR, Hardy RJ, Gregory JS, Barr RJ, Martin KR, Adams JE, Kuh D, Aspden RM, Cooper R. Associations between back pain across adulthood and spine shape in early old age in a British birth cohort. Sci Rep. 2018 Nov 5;8(1):16309. doi: 10.1038/s41598-018-34628-9. PMID: 30397263. Muthuri SG, Saunders FR, Hardy RJ, Pavlova AV, Martin KR, Gregory JS, Barr RJ, Adams JE, Kuh D, Aspden RM, Cooper R. Associations between body mass index across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort Bone. 2017 Aug 22. pii: S8756-3282(17)30312-5. PMID:28842363 PMC5658512 Pavlova AV, Saunders FR, Muthuri SG, Gregory JS, Barr RJ, Martin KR, Hardy RJ, Cooper R, Adams JE, Kuh D, Aspden RM. Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development. J Anat. 2017 Aug;231(2):248-259. PMID: 28561274 PMC5522893
Start Year 2013
 
Description Hip and spine morphologies - Aberdeen Collaboration 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Collboration to look at hip and spine morphologies in the NSHD. The unit will provide the study members for the project, help with coordination of the project, data analysis, creation and editing of manuscripts and writing grant applications.
Collaborator Contribution Coordination of the project, data analysis, creation and editing of manuscripts and writing grant applications.
Impact A grant application has been awarded by the MRC - November 2013 Aberdeen have finished deriving a complete dataset of hip shape mode scores and one on spine shape is due to be delivered soon. Conference abstracts have been submitted by the Aberdeen group LHA is now planning analyses that will be led by them Muthuri and Pavlova submitted papers abstracts submitted Muthuri SG.Associations between body mass index across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort.PMID:28842363 PMC5658512 Pavlova AV. Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development.PMID:28561274 PMC5522893 Ireland A, Saunders FR, Muthuri SG, Pavlova AV, Hardy RJ, Martin KR, Barr RJ, Adams JE, Kuh D, Aspden RM, Gregory JS, Cooper R. Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age. J Bone Miner Res. 2018 Nov 29. doi: 10.1002/jbmr.3627. [Epub ahead of print] PMID: 30496618. Muthuri SG, Pavlova AV, Saunders FR, Hardy RJ, Gregory JS, Barr RJ, Martin KR, Adams JE, Kuh D, Aspden RM, Cooper R. Associations between back pain across adulthood and spine shape in early old age in a British birth cohort. Sci Rep. 2018 Nov 5;8(1):16309. doi: 10.1038/s41598-018-34628-9. PMID: 30397263. Muthuri SG, Saunders FR, Hardy RJ, Pavlova AV, Martin KR, Gregory JS, Barr RJ, Adams JE, Kuh D, Aspden RM, Cooper R. Associations between body mass index across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort Bone. 2017 Aug 22. pii: S8756-3282(17)30312-5. PMID:28842363 PMC5658512 Pavlova AV, Saunders FR, Muthuri SG, Gregory JS, Barr RJ, Martin KR, Hardy RJ, Cooper R, Adams JE, Kuh D, Aspden RM. Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development. J Anat. 2017 Aug;231(2):248-259. PMID: 28561274 PMC5522893
Start Year 2013
 
Description Incontinence collaboration (L Cardozza) 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Provide life course expertise, complete data analysis, manuscript preparation
Collaborator Contribution Provide expertise in incontinence research
Impact Tsui A. Vascular risk factors for male and female urgency urinary incontinence at age 68 years from a British birth cohort study.PMID: 29512315
Start Year 2016
 
Description Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution UCL is the main partner for this collaboration NSHD data sharing, revision of manuscripts
Collaborator Contribution Analysis and interpretation of NSHD (and other) data Contribute to the scientific development of the collaboration Preparation of research papers
Impact PMID 22421340
Start Year 2011
 
Description Life course determinants of kidney function 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Clinical and epidemiological expertise as part of the scientific collaboration, new NSHD clinical data on renal function to be used in conjunction with existing NSHD life course data
Collaborator Contribution By starting a long term collaboration with Dr Dorothea Nitsch, a nephrologist and a postdoctoral scientist we will expand the clinical and analytical skills in the area of research on renal function
Impact Collaboration led to grant from KRUK on 'exploring early life course determinants of chronic kidney disease'
Start Year 2009
 
Description MRC guidelines on biomarkers of healthy ageing 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution Three LHA scientists contributed to the creation of the new MRC guidelines on biomarkers of healthy ageing and also helped to organise a workshop on the subject.
Collaborator Contribution The external collaborators also contributed to the creation of the new MRC guidelines on biomarkers of healthy ageing and helped to organise a workshop on the subject.
Impact Creation of the new MRC guidelines is still in progress - drafts are being circulated Kuh et al PMID: 24456831 PMID: 26373927
Start Year 2011
 
Description MRC guidelines on biomarkers of healthy ageing 
Organisation University of Birmingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Three LHA scientists contributed to the creation of the new MRC guidelines on biomarkers of healthy ageing and also helped to organise a workshop on the subject.
Collaborator Contribution The external collaborators also contributed to the creation of the new MRC guidelines on biomarkers of healthy ageing and helped to organise a workshop on the subject.
Impact Creation of the new MRC guidelines is still in progress - drafts are being circulated Kuh et al PMID: 24456831 PMID: 26373927
Start Year 2011
 
Description MRC guidelines on biomarkers of healthy ageing 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Three LHA scientists contributed to the creation of the new MRC guidelines on biomarkers of healthy ageing and also helped to organise a workshop on the subject.
Collaborator Contribution The external collaborators also contributed to the creation of the new MRC guidelines on biomarkers of healthy ageing and helped to organise a workshop on the subject.
Impact Creation of the new MRC guidelines is still in progress - drafts are being circulated Kuh et al PMID: 24456831 PMID: 26373927
Start Year 2011
 
Description MRC guidelines on biomarkers of healthy ageing 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Three LHA scientists contributed to the creation of the new MRC guidelines on biomarkers of healthy ageing and also helped to organise a workshop on the subject.
Collaborator Contribution The external collaborators also contributed to the creation of the new MRC guidelines on biomarkers of healthy ageing and helped to organise a workshop on the subject.
Impact Creation of the new MRC guidelines is still in progress - drafts are being circulated Kuh et al PMID: 24456831 PMID: 26373927
Start Year 2011
 
Description Secondment to MRC Research Data Support Service (DSS) Project 
Organisation Medical Research Council (MRC)
Country United Kingdom 
Sector Academic/University 
PI Contribution Secondment to the MRC Research Data Support Service (DSS) Project. One is Programme Manager for one year 50% FTE 1. Maximise the use of the Gateway by researchers by: - improving promotion and visibility of the Gateway - improving the experience of accessing and using the Gateway - increasing the publication of informative metadata into Gateway by engaging a further 10+ MRC 'strategic' cohorts - improving the quality of existing study information and metadata - facilitating easy acquisition of new sets of study and variable descriptions 2. Validate the utility of the Gateway to researchers by: - ensuring new uses and outputs are documented by studies - collecting feedback from a range of users 3. Coordinate development, validation and implementation of metadata standards and tools by: - working with CLOSER (ESRC / MRC funded Cohort and Longitudinal Studies Enhancement Resources) and UK Data Service (UKDS) for the Population Health Science (PHS) community - working with MRC Head Office to ensure coordination with related metadata initiatives for patient / clinical cohorts and data discovery and sharing with omics / bioinformatics imaging and e-health. - engaging with research, informatics and data management communities and with stakeholder organisations e.g. JISC, EBI - aligning DSS and CLOSER search platforms within a wider system of interoperable data and tissue services. 4. Promote and support the implementation of MRC Research Data policy by: - enabling studies to publish metadata by providing initial assistance and tools for ingest - providing examples of good practice - identifying needs and feeding into the wider MRC policy
Collaborator Contribution Members of the MRC will work with the seconded staff to complete the project and objectives listed in the above contribution section
Impact none
Start Year 2013
 
Description Vitamin D 
Organisation University College London
Department Institute of Child Health
Country United Kingdom 
Sector Academic/University 
PI Contribution We completed analysis on the genotyping that was done on NSHD study memebers
Collaborator Contribution The UCL group paid for genotyping of NSHD samples and carried out meta analysis in collaboration with a number of cohort studies
Impact Vimaleswaran et al PMID:24974252
Start Year 2011
 
Description Yale Collaboration 
Organisation Yale University
Country United States 
Sector Academic/University 
PI Contribution NSHD data sharing, analysis, interpretation, drafting and revision of papers
Collaborator Contribution Analysis and interpretation of NSHD on lung function and health outcomes and another proposal investigating BMI. Drafting and revision of NSHD papers.
Impact Three clinical research fellows at Yale University are working on NSHD data Research visit but LHA Post doc to Yale Ó Hartaigh et al PMID:24850484 Paper Bann et al PMID: 25647685
Start Year 2012
 
Title SWIFT (Secure web based infrastructure for the NSHD) 
Description SWIFT is a web based data discovery and data sharing tool incorporating a 'Google' like search engine and software for dealing with data sharing governance processes and downloading of data for approved projects. MRCT are currently advising about copyright 
IP Reference  
Protection Copyrighted (e.g. software)
Year Protection Granted 2008
Licensed No
Impact The future impact could be considerable for MRC data sharing activities and is being integrated with initiatives under the MRC Data Support Services
 
Title SWIFT - a web based data discovery and data sharing tool 
Description The final prototype of SWIFT was completed at the end of 2007, funded by MRC data access project. Further bid was awarded to fund transition of prototype to product and transition to service in 2010 / 11 and run a 3 years service from 2010 - 2013. Metadata website for NSHD has been created. 
Type Support Tool - For Fundamental Research
Current Stage Of Development Small-scale adoption
Year Development Stage Completed 2009
Development Status Under active development/distribution
Impact Remote access by external collaborators to NSHD data archive of >10,000 variables 
 
Description A life course approach to women's health and ageing. Women's Reproductive Health across the Lifecourse - Implications for Public Policym (Edinburgh) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Presentation - A life course approach to women's health and ageing. Women's Reproductive Health across the Lifecourse - Implications for Public Policy at The Royal Society of Edinburgh. There was also a report and policy paper (which has just been launched 29th Oct) "Women's Reproductive Health across the Lifecourse - Implications for Public Policy" to which Programme Leader contributed.

Report was produced as an output from the conference.
Year(s) Of Engagement Activity 2013
URL http://www.royalsoced.org.uk/cms/files/events/reports/2012-2013/Womens%20Reproductive%20Health%20-%2...
 
Description Ageing Well Discussion BUPA/PHE 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact The Director was invited to attend a discussion on Ageing Well with Andrew Cannon, Managing Director of Bupa Care Services, to hear from Duncan Selbie, Chief Executive of Public Health England The subject was promoting health and wellbeing among older people.

None to report
Year(s) Of Engagement Activity 2013
 
Description Article about the NSHD by study member 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact An article was written in the guardian newspaper by an NSHD study member about his life in the study

Raising the profile of the NSHD to a more general audience
Year(s) Of Engagement Activity 2013
URL http://www.theguardian.com/society/2013/jan/15/generations-apart-survey-of-health-and-development
 
Description Article in The Guardian 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Article in the Guardian newspaper by a survey member in the study reporting discussions with

increased interest from other newspapers
Year(s) Of Engagement Activity 2008
 
Description Article in the Centre for Longitudinal Studies Institute of Education newsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Health professionals
Results and Impact Celebrating 65 years of research into the health and lives of British people

Advertising the cohort to other members of the 'cohort' research community.
Year(s) Of Engagement Activity 2011
 
Description Article in the Times newspaper about NSHD - 65th 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact NA

Increased awareness of NSHD and MRC
Year(s) Of Engagement Activity 2011
 
Description BBC Radio 4 Woman's Hour 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Director of the Unit and a study member were interviewed about the NSHD http://www.bbc.co.uk/iplayer/console/b00yz54q/Womans_Hour_04_03_2011



Raising the profile of the NSHD and MRC to the general public
Year(s) Of Engagement Activity 2011
 
Description BBC World Service interview 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Radio interview about the NSHD 65th celebrations

Increase awareness of NSHD
Year(s) Of Engagement Activity 2011
 
Description BBC radio 4 Generations Apart show 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Radio show exploring the past, present and future of longitudinal research. Clips from study members who attended the 65th birthday party at the British Library were played and opinions expressed by the Unit Director.


Raised the profile of longitudinal research to a wider public audience
Year(s) Of Engagement Activity 2011
 
Description BBC radio Wales interview with a study member 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact BBC Radio Wales (23.5.11) - Study member interviewed on Good Morning Wales

Raising the profile of the study and MRC in Wales specifically
Year(s) Of Engagement Activity 2011
 
Description BMJ Podcast 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact LHA collaborator interviewed for a podcast on BMJ article -Health symptoms during midlife in relation to menopausal transition: British prospective cohort study.


Increase awareness of NSHD and life course approach
Year(s) Of Engagement Activity 2012
 
Description Birth cohort Data and the Menopause 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Health professionals
Results and Impact The Pat Patterson lecture, British Menopause Society 19th Annual conference

interest
Year(s) Of Engagement Activity 2008
 
Description Blog for British Geriatrics Society 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Health professionals
Results and Impact Blog for British Geriatrics Society to go live 8 am Nov 12th, 2013 on paper about how more educated people have a later onset of terminal decline. The blog will appear under the title "the more you study, the later you drop".


Too early to report. Will disseminate the findings of one of researcher's publications to a less academic audience.
Year(s) Of Engagement Activity 2013
 
Description British Library 65th Birthday Party 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Participants in your research and patient groups
Results and Impact This event was mainly held for the study particpants but other health professionals were also invited. There were talks from the Unit Director, memories read out by study members and a Q and A panel discussion

This event showed the study members that the Unit and MRC appreciate their continued support and participation in the NSHD. It also showcased the main findings from the study so far and allowed the study members to meet each other for the first time.
Year(s) Of Engagement Activity 2011
 
Description British Library Social Science Research Blog 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The Engagement Development Manager at the British Library visited the Unit and wrote a blog post about the National Survey of Health and Development (NSHD)

Raising the profile of the NSHD with a new audience
Year(s) Of Engagement Activity 2013
URL http://britishlibrary.typepad.co.uk/socialscience/2013/01/research-participation-and-autobiography.h...
 
Description Canadian Broadcasting Corporation discussion 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Canadian Broadcasting Corporation (24.4.11) Discussion about the future of epidemiology http://www.cbc.ca/podcasting/includes/sundayedition.xml

Raising the profile of the NSHD and MRC internationally
Year(s) Of Engagement Activity 2011
 
Description Canadian Lifestyle and Fitness Institute article on HALCyon paper 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact A lay summary was written by the Canadian Fitness and Lifestyle Research Institute about a HALCyon paper on childhood socioeconomic circumstances and physical capability.

Increase the awareness (in Canada) of the HALCyon research programme and the importance of cross cohort work.
Year(s) Of Engagement Activity 2012
 
Description DIPEX website on Menopause 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Primary Audience Public/other audiences
Results and Impact We were co-applicants for an NIHR grant with our colleagues who run the award winning 'Health talk on line' (previously called DIPEX) to help them set up a website for the general public on managing the menopause. We acted principally as scientific advisors

http://www.healthtalkonline.org/Later_life/menopause is used by many thousands of women since its launch.
Year(s) Of Engagement Activity 2010,2011
URL http://www.healthtalkonline.org/Later_life/menopause
 
Description HALCYon Project Summary Brochure 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact A plain english brochure was created which summarised the main findings from the HALCyon research programme. It has been disseminated to study members, on our website and the New Dynamics of Ageing website and at conferences.

Increased awareness of the findings from the HALCyon programme and the cohorts that were used within this research programme
Year(s) Of Engagement Activity 2014
 
Description HALCYon book launch 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact A book launch was arranged to promote the findings from the HALCyon research programme

Shared knowledge of the HALCyon findings which were published in a book 'A life course approach to healthy ageing'.
Year(s) Of Engagement Activity 2014
 
Description History of the Census and Society: Why Everyone Counts 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact LHA contributed to the exhibition at the British Library in 2011 on the history of the Census and Society: Why Everyone Counts. A short history of NSHD was included, as an example of a social survey, along with a description and findings from a special study led by one of the NIA funded research fellows, that linked census data about social and demographic characteristics in 1951,1971 and 2001 to the residential histories of NSHD participants.

Increased the profile of the NSHD and raised awareness about social and demographic characteristics.
Year(s) Of Engagement Activity 2011
 
Description House of Lords afternoon tea 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Primary Audience Policymakers/politicians
Results and Impact Study members and members of the House of Lords attended an afternoon tea which presented network opportunities and general discussion.

Promoting the NSHD and MRC to members of the House of Lords
Year(s) Of Engagement Activity 2011
 
Description ITV online mini documentary 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact ITV online (not available anymore, but they had our mini-documentary on their website with a brief story, in the week beginning Monday 28.3.11

Raising the profile of NSHD to a wider audience. Promoting interest in the study.
Year(s) Of Engagement Activity 2011
 
Description Innovations and progress in health care for women 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Health professionals
Results and Impact Diana Kuh :International Meeting on Innovations and Progress in healthcare for women. The UCL Elizabeth Garrett Anderson Institute for Women's Health. Queen Elizabeth II Conference Centre. London 7-8th April 2008 and at RCOG Nov 2009

generation of interest in NSHD. Also led to a RCOG Scientific Advisory Opinion Paper 27 published in Aug 2011 'Why should we consider a life course approach to women's health care?
Year(s) Of Engagement Activity 2008,2009,2010,2011
 
Description Knowledge Transfer Steering Group 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Health professionals
Results and Impact LHA and Help the Aged have set up a Knowledge Transfer Steering Group with non academic partners and scientists to disseminate widely the results of the HALCyon collaboration and influence policy makers

Group has met 4 times and is developing most effective ways to raise profile of HALCyon
Year(s) Of Engagement Activity 2009
 
Description Launch of the Academy of Social Sciences Publication 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Talk given by Director on 'Improving the well-being of ageing baby boomers' at the Launch of the Academy of Social Sciences Publication ' Making the case for the Social Sciences- Longitudinal Studies

The booklet, sponsored by SAGE, is the eighth in the Making the Case for the Social Sciences series, which is published by the Academy of Social Sciences and the Campaign for Social Science. Each booklet summarises a different area of important social science research. Launched in 2013 so too early to note any impacts.
Year(s) Of Engagement Activity 2013
URL http://www.acss.org.uk/docs/Making%20the%20Case/ACSS_Longitudinal_studies_FINAL.pdf
 
Description Local Newspaper article about a study member- Leicester 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Oadby People (6.4.11) - Article on study member taking quotes from Douglas Children documentary. http://www.oadbypeople.co.uk/news/did-little-girl-help-change-Britain-rsquo-s/story-10924769-detail/story.html

Raising profile of NSHD and MRC at a regional level
Year(s) Of Engagement Activity 2011
 
Description Longitudinal studies: lessons for science and policy 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Primary Audience Public/other audiences
Results and Impact Invited presenter at this conference at the British Library on May 10th 2011 about the value of NSHD and HALCyon for science and policy

Increased profile of NSHD and other UK cohort studies
Year(s) Of Engagement Activity 2011
 
Description MRC Council Meeting. Cross-Unit Collaboration 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Director invited to talk about cross unit collaborations at the MRC Open Council Meeting
Collaborative studies on social & biological aspects of ageing: the HALCyon programme
10th June
London

none to report
Year(s) Of Engagement Activity 2013
 
Description MRC Network News 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact article in Network News about the Unit

not known
Year(s) Of Engagement Activity 2008
 
Description MRC centenary event at London Science Museum 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact The Unit took part in the Life Game at the London Science Museum for the MRC Centenary Open Week celebrations. Numerous visitors who visited the Science Museum attended the festival where they could visit interactive stands from various MRC research centres. Our stand let people take part in a mini data collection where the public had to test their memory, grip and balance similar to the way we test this in our cohort. The message we wanted to get across to people was that it is never too late to start living a long and healthy life. In the feedback session at the end of the Life Game informal feedback told us that quite a number of people were mentioning taking part in our activities.

Impacts include raising the profile of the MRC and our research unit and also trying to encourage people to live an active life.
Year(s) Of Engagement Activity 2013
URL http://www.centenary.mrc.ac.uk/events/science-festival/
 
Description Media around Lancet IL6 paper 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Article in the daily express and numerous online publications explaining that the interleukin 6 (IL6) receptor - a protein involved in the inflammatory process - plays a key role in the development of the condition. By using drugs that block this inflammatory pathway, scientists may be able in the future to develop effective new treatments to prevent CHD.


Increased awareness of CHD and the benefit of using large genetics consortia in research
Year(s) Of Engagement Activity 2012
 
Description Media around the PLoS One Clinical Disorders paper 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Telegraph and Express online articles and other numerous online articles about recently published paper in PLoS one about the number of people who have clinical disorders once they reach retirement age.

Raising the awareness that these findings will have on the health service and promoting the case to invest in primary care.
Raising the profile of the NSHD and the importance of its research.
Year(s) Of Engagement Activity 2012
 
Description Ministerial seminar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Primary Audience Participants in your research and patient groups
Results and Impact ESRC organised a seminar with David Willetts to highlight the value of longitudinal data

Enhanced profile of NSHD and HALCyon
Year(s) Of Engagement Activity 2011
 
Description NDA findings brochure 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The New Dynamics of Ageing programme which funded the HALCyon programme created a findings document summerising the results of the HALCyon programme which was distributed to their local networks

Increased awareness of the HALCyon findings and a life course approach to healthy ageing. Increased awareness of longitudinal studies and the cohorts that were involved in HALCyon
Year(s) Of Engagement Activity 2014
 
Description NPR radio broadcast 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact The Director participated in a radio broadcast for National Public Radio in America. Also featured comments from NSHD study members.

Raising the profile of the NSHD in America.
Year(s) Of Engagement Activity 2011
 
Description NSHD booklet: Celebrating 65 years of research into the health and lives of British people 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Primary Audience Public/other audiences
Results and Impact Booklet covering the history, key findings, impact and future direction of the NSHD. Aimed at study members, an interested lay public and relevant healthcare and scientific communities.

Distributed to:
? 3100 remaining study members
? 200 external stakeholders
? Study member/stakeholder event attendees
? Exhibition attendees


Increasing awareness of the NSHD and its important research findings
Year(s) Of Engagement Activity 2011
 
Description Newspaper article - Cardiff 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact South Wales Echo (24.5.11) - http://www.walesonline.co.uk/cardiffonline/cardiff-news/2011/05/24/cohort-born-in-1946-mark-65-years-of-research-study-in-cardiff-ceremony-91466-28749870/

Raising the profile of the study in Wales
Year(s) Of Engagement Activity 2011
 
Description Online News article about the birthday party held for study members - Edinburgh 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Edinburgh Evening News online (11.6.11): Scots praised as baby boomer study enters 65th year http://edinburghnews.scotsman.com/edinburgh/Scots-praised-as-baby-boomer.6783426.jp

Specific profile raising of NSHD and MRC in Scotland
Year(s) Of Engagement Activity 2011
 
Description Online article about the study and a study member - Wales 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Article on Health and Wales website (The gateway to information on health and NHS services in Wales) - A celebration of life under the microscope http://www.wales.nhs.uk/news/19301


Raising the profile of the study - generating more media interest
Year(s) Of Engagement Activity 2011
 
Description Podcasts on HALCyon website 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Primary Audience Public/other audiences
Results and Impact 10 podcasts/videos were recorded for the website. Each different work package was explained by the lead scientist.

Explaining the research is a more user friendly way will help to increase the understanding of the HALCyon research grant and what it is trying to acheive
Year(s) Of Engagement Activity 2008
 
Description Press release about CKD paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Media coverage of a NSHD paper 23559581 including the scotsman newspaper and online blogs

Publicising the results of NSHD research to a non academic audience
Year(s) Of Engagement Activity 2013
URL http://www.scotsman.com/news/health/obesity-linked-to-kidney-disease-in-later-life-1-2878910
 
Description Press release about personality research paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Press release about a paper published in Journal of Research in Personality

Publicising results from a paper that uses NSHD data
Year(s) Of Engagement Activity 2013
URL http://www.southampton.ac.uk/mediacentre/news/2013/jul/13_137.shtml http://www.psmag.com/health/extr...
 
Description Production of NSHD documentary: The Douglas Children 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Primary Audience Public/other audiences
Results and Impact Short film about the NSHD, including interviews with two study members talking about their experiences of being involved throughout their lives, and an additional birthday message from Dame Joan Bakewell.

Featured as part of touring exhibition and on NSHD website and MRC Comms channel on YouTube (152 views). Also featured on ITV online week beginning 28/3/11.


Raising the profile of the NSHD
Year(s) Of Engagement Activity 2011
 
Description Public Bodies event at the DANA Centre Science Museum 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Primary Audience Public/other audiences
Results and Impact I was one of 4 at a public event at the DANA Centre organised by the MRC on engaging the public in medical research

Enhanced the profile of NSHD
Year(s) Of Engagement Activity 2011
 
Description Public talk on NSHD 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Talk to Troutbeck WI

Interest in NSHD
Year(s) Of Engagement Activity 2008
 
Description Radio 2 Programme: Generations Apart, Series 2 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact A NSHD study member took part in a radio show called Generations Apart which tracks two groups of people born at the forefront of their generations - the baby boomers born in 1946 and the children of the nineties, born into the era of the world wide web.

Raising the profile of the NSHD and cohort studies
Year(s) Of Engagement Activity 2013
URL http://www.bbc.co.uk/programmes/b01ptzm3
 
Description Radio Interview on a Candian Science Show 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Interview on a radion show that was looking at the scientific perspective on the causes and effects of aging, and how they change over a lifetime.Skeptically Speaking (Canada 24.4.11) - http://skepticallyspeaking.ca/episodes/109-a-lifetime-of-data

Raising the profile of the NSHD and MRC internationally
Year(s) Of Engagement Activity 2011
 
Description Radio interview - Canadian Broadcasting Corporation 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Canadian Broadcasting Corporation (8.3.11) Largest cohort turns 65 - Diana Kuh radio interview

International profile raising of the NSHD and MRC
Year(s) Of Engagement Activity 2011
 
Description Song dedication on Magic Radio Station 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Participants in your research and patient groups
Results and Impact A song was dedicated to all the study members of the NSHD (3.3.11)

Shows the survey members that we appreciate their continued support and participation in the study. Helps to decrease the number of people who drop out of the study which is good for the scientific analysis.
Year(s) Of Engagement Activity 2011
 
Description Spanish article about the NSHD 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Article on spanish news website
Agencia SINC (Spain, 24.5.11) - http://www.agenciasinc.es/esl/Reportajes/Los-ninos-de-Douglas-65-anos-bajo-observacion


Raising the profile of the NSHD and MRC cohort research in Spain
Year(s) Of Engagement Activity 2011
 
Description Three regional birthday parties 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Primary Audience Participants in your research and patient groups
Results and Impact This event was mainly held for the study particpants but other health professionals were also invited. There were talks from the Unit Director, memories read out by study members and a lively discussion amongst study members.

This event showed the study members that the Unit and MRC appreciate their continued support and participation in the NSHD. It also showcased the main findings from the study so far and allowed the study members to meet each other for the first time.
Year(s) Of Engagement Activity 2011
 
Description Travelling exhibition about the NSHD - 4 different locations 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Primary Audience Public/other audiences
Results and Impact Exhibition highlighting some of the key findings and areas of impact of the NSHD eg on healthcare policy. Also includes 'The Douglas Children' documentary and a panel highlighting the need for the continued involvement of the public in medical research.

4 - 17 March: Exhibition hosted by Science Museum's Dana Centre

April - June: Exhibition toured hospitals around UK

Four Central Manchester University Hospitals
Queen Elizabeth Hospital, Birmingham
University Hospital of Wales, Cardiff
Royal Infirmary of Edinburgh


Not possible to quantify visitor numbers due to open public access, but positive feedback received from all host venues.
Year(s) Of Engagement Activity 2011
 
Description UCL Science Festival 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact The Unit took part in the UCL Science Festival for the MRC Centenary Open Week celebrations run by all the MRC units based at UCL. Our stand let people take part in a mini data collection where the public had to test their memory, grip and balance similar to the way we test this in our cohort. The message we wanted to get across to people was that it is never too late to start living a long and healthy life. Around 500 people attended the event.

The aim of the event was to promote the MRC and our research unit as well as trying to tell people about our research and encourage them to increase their amount of physical activity.
Year(s) Of Engagement Activity 2013
 
Description Web article on Science2day - Longest running British 'baby-boomer' study shows importance of childhood 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Web article was picked up from the MRC website and published on Science2day (3.3.11).http://www.science2day.co.uk/industry/science/2011/03/03/longest-running-british-baby-boomer-study-shows-importance-childhood

Raising the profile of the NSHD
Year(s) Of Engagement Activity 2011
 
Description Web article on physorg.com about NSHD 65th celebrations 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Article written on an online science news site - content provided by MRC.
http://www.physorg.com/news/2011-03-baby-boomer-importance-childhood.html

Raising the profile of the NSHD to a more general science audience and also members of the general public.
Year(s) Of Engagement Activity 2011
 
Description Whitehall seminar on longitudinal data 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Primary Audience Policymakers/politicians
Results and Impact 50 Whitehall researchers and policymakers attended a seminar about longitudinal data.

Enhanced the profile of NSHD and HALCyon
Year(s) Of Engagement Activity 2011
 
Description Womb to tomb article in The Times 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact An article was written 'Womb to tomb' in The Times newspaper highlighting the importance of the NSHD.

Raised profile of the NSHD to a lay audience
Year(s) Of Engagement Activity 2011