The Hertfordshire Cohort Study

Lead Research Organisation: MRC Lifecourse Epidemiology Unit

Abstract

The Hertfordshire Cohort Study (HCS) is a study of 3000 men and women born during 1931-39 and still resident in the English county of Hertfordshire. Information on their birthweight, weight at age one year, way they were fed as infants, and details of childhood illnesses up to age five years has been preserved. Participants were traced and came to a clinic at age 60 - 75 years where they completed lifestyle and dietary questionnaires, their body build was assessed and where a range of blood samples were taken, including DNA samples and tests for cholesterol and blood sugar. A heart tracing was made and the participants lung function tested. One thousand participants also underwent a bone density test and had x-rays of their knees taken; some 650 of these individuals returned a few years later to have a repeat bone density test, as well as other measures of bone health (peripheral quantitative computed tomography, or pQCT). Muscle strength was also tested at baseline and follow up. Some subjects also took part in a trial of the benefits of physical activity. A postal follow up to enquire about health since baseline clinic visit has recently been performed.

Technical Summary

The Hertfordshire Cohort Study (HCS) comprises a study of 3000 men and women born during 1931-39 and still resident in the English county of Hertfordshire. Information available includes birthweight, weight at age one year, method of infant feeding, and details of childhood illnesses up to age five years. Detailed phenotypic information is available from a clinic visit at age 60-75 years. DNA has been collected on all subjects. The study was initially established to evaluate interactions between the genome and early environment in the aetiology of programmed chronic disorders such as cardiovascular disease and osteoporosis/osteoarthritis/sarcopenia. Prior to the inception of the 1931-39 cohort study, research in Hertfordshire had been based on subjects born during 1911-1930. This group was felt to be too small a sample for studies examining associations with relevant clinical outcomes or to study interactions between genetic markers of disease risk, the intrauterine and early postnatal environment and adult disease risk. As a consequence, an additional, larger sample of younger people who still lived in Hertfordshire was recruited (The HCS). Detailed information on medical and lifestyle factors was recorded. The Rose/WHO chest pain questionnaire was administered; respiratory symptoms were recorded using the MRC questionnaire. The habitual diet of each subject was assessed using a modified EPIC food frequency questionnaire and a detailed 24 hour food diary. Anthropometric measurements were made. Sitting blood pressure and spirometry were also recorded. Fasting venous blood samples were taken to measure concentrations of glucose, insulin, proinsulin, and 32-33 split proinsulin, total and high density lipoprotein cholesterol, triglycerides, apolipoprotein A1 and B, and fibrinogen. Glucose and insulin concentrations were measured 30 and 120 minutes after a standard (75g) oral glucose load. DNA samples were obtained from each subject. Standard 12-lead electrocardiography was performed. Bone mineral density was measured at the lumbar spine and proximal femur in a sample of 1,000 subjects (500 men, 500 women) using a Hologic QDR4500 instrument. Radiographs were obtained of both knees (standing antero-posterior and lateral) under standardised conditions. At a follow up visit in 2006, some 650 subjects completed a further lifestyle questionnaire and underwent repeat bone densitometry and peripheral quantitative computed tomography (pQCT) of radius and tibia (Stratec 4500). Physical function was assessed. Substudies in this group include an aetiological trial of physical activity in men of varying birthweight. A postal follow up to ascertain clinically relevant events since baseline clinic visit has recently been performed.

Organisations

Publications

10 25 50
publication icon
Abrahamsen B (2015) Life Expectancy in Patients Treated for Osteoporosis: Observational Cohort Study Using National Danish Prescription Data. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

publication icon
Akesson K (2013) Capture the Fracture: a Best Practice Framework and global campaign to break the fragility fracture cycle. in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

 
Title ASBMR slide kit and videos 
Description ASBMR slide kit and videos 
Type Of Art Film/Video/Animation 
Year Produced 2016 
Impact ASBMR slide kit and videos 
 
Title ASBMR slide kit and videos 2017 
Description ASBMR slide kit and videos 2017 
Type Of Art Film/Video/Animation 
Year Produced 2017 
Impact ASBMR slide kit and videos 
 
Title DXA video UK Biobank 
Description DXA video UK Biobank 
Type Of Art Film/Video/Animation 
Year Produced 2014 
Impact DXA video UK Biobank 
 
Title International Osteoporosis Foundation Slide kit/ videos: WCO 
Description Slide kit and video interviews based on science presented at 2015 World Congress in Osteoporosis 
Type Of Art Film/Video/Animation 
Year Produced 2015 
Impact Widely viewed 
 
Title International Osteoporosis Foundation Video 
Description International Osteoporosis Foundation Video 
Type Of Art Film/Video/Animation 
Year Produced 2014 
Impact International Osteoporosis Foundation Video 
 
Title International Osteoporosis Foundation:Slide kit and videos: ASBMR 
Description Production of slide kit and video interviews based on science presented at the 2015 ASBMR scientific meeting. 
Type Of Art Film/Video/Animation 
Year Produced 2015 
Impact Widely viewed. 
 
Title LifeLab 
Description Picture 
Type Of Art Image 
Year Produced 2014 
Impact LifeLab 
 
Title National Osteoporosis Society Video 
Description National Osteoporosis Society Video 
Type Of Art Film/Video/Animation 
Year Produced 2014 
Impact National Osteoporosis Society Video 
 
Title Osteoarthritis webinar 
Description Osteoarthritis webinar 
Type Of Art Film/Video/Animation 
Year Produced 2014 
Impact Osteoarthritis webinar 
 
Title WCO slide kit and videos 2016 
Description WCO slide kit and videos 2016 
Type Of Art Film/Video/Animation 
Year Produced 2016 
Impact WCO slide kit and videos 2016 
 
Title WCO slide kit and videos 2017 
Description WCO slide kit and videos 2017 
Type Of Art Film/Video/Animation 
Year Produced 2017 
Impact WCO slide kit and videos 2017 
 
Description ASBMR Professional Practice Committee
Geographic Reach North America 
Policy Influence Type Membership of a guideline committee
Impact Provision of bone densitometry with ISCD and IOF.
 
Description Arthritis Research UK (Fellowships Committee)
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact As a member of the ARUK Clinical Studies Group in Metabolic Bone Disease, I reviewed several large, randomised controlled trials and fellowship applications answering important questions within musculoskeletal medicine.
 
Description Can we identify patients with high risk of osteoporosis progression who will respond to treatment?
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Improved management of osteoarthritis
 
Description Chair, International Osteoporosis Foundation (Scientific Committee) [Prof C Cooper]
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact Multiple reports and guidelines on: 1) fracture incidence worldwide; 2) trends in hip fracture worldwide over time; 3) variation in vitamin D status worldwide; 4) hazards of long-term anti-osteoporosis therapy; 5) definition of inadequate clinical response; 6) guidelines for management of glucocorticoid-induced osteoporosis. All published as peer reviewed guidance and position papers (Osteoporosis International, 2011/12).
 
Description Chair, MRC Population Health Science Research Network (Prof C Cooper)
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
Impact National advice to UK Department of Health on behaviour change; population science; national public health strategy.
 
Description Commented on NICE Bisphosphonate MTA
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
 
Description Contribution of MAVIDOS findings to SACN consultation/ PHE guidance
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Improved understanding of the need for vitamin D supplementation at the population level, particularly in winter months.
 
Description Contribution to SACN vitamin D guidance
Geographic Reach National 
Policy Influence Type Citation in other policy documents
 
Description Contribution to many government advisory panels, eg SACN, DoH, NICE
Geographic Reach National 
Policy Influence Type Participation in advisory committee
Impact Osteoporosis international and national guidelines.
 
Description European Working Group: Osteoarthritis
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact European guidelines for the management of osteoarthritis.
 
Description European regulatory guidelines for osteoarthritis
Geographic Reach Europe 
Policy Influence Type Citation in other policy documents
Impact Improved management of osteoarthritis
 
Description FRAX-based intervention thresholds
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Improved management of osteoporosis
 
Description Global Alliance for Musculoskeletal Disease
Geographic Reach Multiple continents/international 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Global Alliance for Musculoskeletal Disease
 
Description Guidelines for osteonecrosis of the jaw
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Improved management of osteoporosis
 
Description IOF Guideline Working Group: Biochemical Markers
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact International guidelines on use of biochemical bone turnover markers.
 
Description IOF Guideline Working Group: Epidemiology
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact Characterisation of global burden of osteoporosis and development of European and international guidelines for osteoporosis care.
 
Description IOF Guideline Working Group: Secondary Fracture Prevention
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact International guideline for establishment of secondary fracture prevention services (Capture the Fracture).
 
Guideline Title IOF guidelines for the management of ONJ
Description IOF guidance on ONJ
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in clinical guidelines
Impact IOF guidelines on ONJ
 
Guideline Title Use of FRAX Risk Assessment System in management of osteoporosis
Description IOF/WHO/ISCD Osteoporosis Guidelines
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in clinical guidelines
Impact Widespread utilisation of FRAX algorithm in North America, Europe, Latin America, Asia, Middle-East and Africa.
 
Description Influence on national vitamin D policy, DH, NICE, SACN
Geographic Reach National 
Policy Influence Type Participation in a national consultation
Impact Recommendation of vitamin D supplementation in pregnancy, reduced risk of early adverse events related to vitamin D insufficiency.
 
Description Lifecourse nutrition for musculoskeletal ageing
Geographic Reach Europe 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Improved management of osteoporosis
 
Description MRC Cohort Strategy
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact National overview of MRC cohorts.
 
Description MRC Guidance on Process Evaluation
Geographic Reach Asia 
Policy Influence Type Membership of a guidance committee
Impact MRC guidance for process evaluatoin
 
Description Management of glucocorticoid osteoporosis
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Improved management of osteoporosis
 
Description Map of Medicine OP and Vitamin D
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
Impact Improved and more efficient treatment of osteoporosis and vitamin D deficiency
 
Description NICE
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
Impact Co-authorship and citation in NICE Technology Appraisal on primary and secondary fracture prevention as well as NICE Clinical Guideline on fracture risk assessment. Publication of editorial (BMJ; 2012)
 
Description NICE Guideline Development Group: Osteoporosis
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
Impact Published guideline for treatment of postmenopausal osteoporosis.
 
Description NICE OP
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description NOGG revised guidance
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
Impact Guidance on assessment and treatment of osteoporosis
 
Guideline Title National Osteoporosis Guideline Group
Description NOGG; revised thresholds
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
Impact Optimized fracture risk assessment
 
Description National Osteoporosis Guideline Group
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
Impact National guideline on use of clinical risk factors and DXA assessment of bone density to target treatment for osteoporosis. Guideline published.
 
Description National Osteoporosis Guideline Group 2017 (NCH)
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Description National Osteoporosis Society
Geographic Reach National 
Policy Influence Type Participation in a national consultation
Impact As Chairman of the Board of Trustees of this national charity, I gave evidence to the House of Lords Select Committee on Ageing, as well as contributing written responses on water fluoridation and musculoskeletal research over the period 2007-2009.
 
Guideline Title National Osteoporosis Society Vitamin D Guidelines 2013
Description National Osteoporosis Society Vitamin D Guidelines 2013
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
Impact Extensive feedback
 
Description Participation on NIHR Report "Better Beginnnings"
Geographic Reach National 
Policy Influence Type Citation in other policy documents
 
Description RCOG guidance on Vitamin D in pregnancy
Geographic Reach National 
Policy Influence Type Citation in clinical reviews
 
Description Risk detection for osteoporosis progression
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Improved management of osteoporosis
 
Description SACN guidance 2016
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Improved vitamin D guidance
 
Description Scientific Advisory Committee on Diet and Nutrition- Public Health England Vitamin D Guidance (NCH)
Geographic Reach National 
Policy Influence Type Citation in other policy documents
 
Description Secondary fracture prevention
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Improved management of osteoporosis
 
Description The position of strontium in today's management of osteoporosis
Geographic Reach Europe 
Policy Influence Type Citation in other policy documents
Impact Improved management of osteoporosis
 
Description Use of symptomatic slow-acting drugs in knee osteoarthritis
Geographic Reach Europe 
Policy Influence Type Citation in other policy documents
Impact Improved management of osteoarthritis
 
Description WHO European Ministerial Conference 2016
Geographic Reach Multiple continents/international 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Report on lifecourse and health
 
Guideline Title Risk assessment and treatment of osteoporosis
Description WHO Risk Assessment Methodology in UK.
Geographic Reach Asia 
Policy Influence Type Citation in clinical guidelines
Impact Widespread utilisation of FRAX algorithm within UK and companion publication (Osteoporosis International; 2011)
 
Description . European Research on Developmental, Birth and Genetic Determinants of Ageing (collaborative project).
Amount £329,977 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 04/2012 
End 03/2015
 
Description Academic Clinical Fellowship Starter Grant
Amount £10,000 (GBP)
Organisation University of Southampton 
Sector Academic/University
Country United Kingdom
Start 05/2015 
End 12/2016
 
Description Arthritis Research UK Centre of Excellence for Sport and Exercise Injuries
Amount £76,000 (GBP)
Organisation Versus Arthritis 
Department Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis
Sector Charity/Non Profit
Country United Kingdom
Start 10/2013 
End 09/2018
 
Description Arthritis Research UK Centre of Excellence for Sport and Exercise Injuries
Amount £2,500,000 (GBP)
Organisation Arthritis Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2013 
End 03/2018
 
Description Arthritis Research UK Centre of Excellence in Epidemiology
Amount £120,410 (GBP)
Organisation Arthritis Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2013 
End 09/2018
 
Description Arthritis Research UK Centre of Excellence in Epidemiology
Amount £2,402,000 (GBP)
Organisation Arthritis Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2013 
End 12/2018
 
Description Arthritis Research UK Clinical Studies Grant
Amount £362,894 (GBP)
Funding ID 21231 
Organisation Arthritis Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2016 
End 09/2021
 
Description BUPA project grant MAVIDOS
Amount £142,686 (GBP)
Organisation BUPA 
Department BUPA Foundation
Sector Private
Country United Kingdom
Start 10/2009 
End 09/2012
 
Description Biomedical Research Centre Nutrition - Respiratory Research with Prof R Read et al
Amount £15,000,000 (GBP)
Organisation National Institute for Health Research 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description Clinical Research Fellowship
Amount £164,135 (GBP)
Organisation Arthritis Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2006 
End 03/2009
 
Description Clinical Research Training Fellowship
Amount £252,397 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2016 
End 08/2019
 
Description Clinical Research Training Fellowship
Amount £252,397 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2016 
End 08/2019
 
Description Cohort Resources Facility
Amount £1,000,000 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 05/2012 
End 04/2017
 
Description Collaborative Project Grant: National Clinical Audit of Rheumatoid & Early Inflammatory Arthritis. Collaborative project with BSR and Northgate.
Amount £172,500 (GBP)
Organisation The Health Quality Improvement Partnership (HQIP) 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2013 
End 01/2016
 
Description Data Management Planning for Secure Services (DMP-SS)
Amount £99,904 (GBP)
Organisation Jisc 
Sector Public
Country United Kingdom
Start 01/2011 
End 12/2012
 
Description Describing habitual levels of physical activity (PA) in older people in terms of impact loads and how this relates to bone and other symptoms (VIBE)
Amount £184,576 (GBP)
Funding ID MR/K024973/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 12/2013 
End 11/2016
 
Description EPOSA
Amount £225,057 (GBP)
Organisation Porticus 
Sector Charity/Non Profit
Country Global
Start 12/2013 
End 11/2016
 
Description ERA HDHL
Amount £1,200,000 (GBP)
Funding ID BB/P028179/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 04/2017 
End 02/2020
 
Description EU Collaborative Project: Food based solutions for Optimal vitamin D Nutrition and health through the life cycle (ODIN)
Amount € 5,980,000 (EUR)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 11/2013 
End 10/2017
 
Description Epigenetic biomarkers and determinants of cardiovascular risk in children (With Prof M Hanson et al)
Amount £1,400,000 (GBP)
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2016 
End 03/2020
 
Description Epigenetic mechanisms linking maternal pre-conceptional micronutrient supplementation with offspring health in India and The Gambia
Amount £486,087 (GBP)
Funding ID MR/N006208/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 05/2015 
End 04/2018
 
Description Epigenetic modification of glucocorticoid receptors by early life events
Amount £103,532 (GBP)
Organisation Chief Scientist Office 
Sector Public
Country United Kingdom
Start 01/2007 
End 12/2008
 
Description HTA Project Grant: Risks and benefits of bisphosphonate use in patients with chronic kidney disease
Amount £340,485 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 06/2015 
End 05/2017
 
Description Health risks and benefits of extended working life (the HEAF study)
Amount £841,392 (GBP)
Organisation University of Southampton 
Department ESRC National Centre for Research Methods
Sector Charity/Non Profit
Country United Kingdom
Start 03/2013 
End 02/2018
 
Description IOF-Servier Young Investigator Research Grant
Amount € 40,000 (EUR)
Organisation Servier Laboratories 
Sector Private
Country France
Start 01/2012 
End 12/2013
 
Description Joint IALSA/HALCyon Program Project: Integrative analysis of longitudinal studies of aging
Amount $7,700,000 (USD)
Organisation National Institute on Aging 
Sector Public
Country United States
Start 03/2013 
End 02/2018
 
Description MRC Capital Award
Amount £134,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2018 
End 03/2019
 
Description MRC Capital Funding
Amount £310,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2017 
End 03/2018
 
Description MRC Capital Funding
Amount £288,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2015 
 
Description MRC Capital Prioritisation Award
Amount £134,000 (GBP)
Organisation University of Southampton 
Department MRC Lifecourse Epidemiology Unit
Sector Public
Country United Kingdom
Start 03/2019 
End 03/2022
 
Description MRC Capital/infrastructure (including equipment
Amount £60,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2014
 
Description MRC Centenary Award
Amount £45,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2012 
End 12/2013
 
Description MRC Lifecourse Epidemiology Unit (and linked programme grants)
Amount £14,400,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2015 
End 03/2020
 
Description MRC UUP Capital Award
Amount £288,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2015 
End 03/2015
 
Description Manualising Individual Placements Support for people with unemployment due to chronic pain and testing the feasibility of a randomised controlled trial.
Amount £317,300 (GBP)
Funding ID 15/108 
Organisation National Institute for Health Research 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 01/2017 
End 03/2019
 
Description Maths, Engineering & Life Sciences: making connections for precision medicine (with Prof Deborah Mackay et al)
Amount £500,000 (GBP)
Funding ID MC_PC_15078 
Organisation Medical Research Council (MRC) 
Department MRC Human Nutrition Research Unit
Sector Public
Country United Kingdom
Start 03/2016 
End 02/2018
 
Description Maths, Engineering and Life Sciences: making connections for precision medicine
Amount £500,000 (GBP)
Funding ID MC_PC_15078 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2016 
End 02/2018
 
Description Mid-Career Equipment Grant: Dr Kumaran Kalyanaraman
Amount £60,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2014
 
Description NIHR
Amount £43,129 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 01/2010 
End 07/2012
 
Description NIHR HTA
Amount £317,327 (GBP)
Organisation National Institute for Health Research 
Department Health Technology Assessment Programme (HTA)
Sector Public
Country United Kingdom
Start 10/2017 
End 09/2020
 
Description NIHR HTA Grant
Amount £340,485 (GBP)
Organisation National Institute for Health Research 
Department NIHR Clinical Research Network (CRN)
Sector Public
Country United Kingdom
Start 06/2015 
End 05/2017
 
Description NIHR PGfAR
Amount £2,166,779 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 10/2017 
End 09/2022
 
Description NIHR Senior Investigator Award
Amount £75,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 10/2014 
End 09/2017
 
Description NOS Project Grant CPRD
Amount £79,905 (GBP)
Organisation National Osteoporosis Society 
Sector Learned Society
Country United Kingdom
Start 01/2014 
End 12/2016
 
Description Programme grant: Maternal and epigenetic determinants of cardiovascular structure and function
Amount £822,366 (GBP)
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2007 
End 12/2012
 
Description Project Grant - The Role of hospital organisation, surgical factors, and the enhanced recovery pathway, on patient outcomes and NHS costs following primary hip and knee replacement surgery: spacial and longitudinal analysis of routine data
Amount £510,503 (GBP)
Funding ID 14/46/02 
Organisation National Institute for Health Research 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 04/2016 
End 03/2018
 
Description Project Grant: Dr Christopher Holroyd. How do pre- and post-natal environmental factors and parental bone mass influence offspring bone size and density
Amount £85,000 (GBP)
Organisation Southampton Rheumatology Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2011 
End 09/2013
 
Description Project Grant: Musculoskeletal health and extended working life
Amount £180,014 (GBP)
Organisation Arthritis Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2012 
End 09/2014
 
Description Project grant: Epigenetic biomarkers and determinants of cardiovascular risk in children
Amount £1,400,000 (GBP)
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2016 
End 03/2020
 
Description Research Project Grant: Describing habitual levels of physcial activity (PA) in older people in terms of impact loads and how this relates to bone and other symptoms.
Amount £184,576 (GBP)
Funding ID MR/K024973/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2016
 
Description Travelling Fellowship
Amount £44,465 (GBP)
Organisation Arthritis Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2006 
End 03/2007
 
Description UK Biobank Imaging
Amount £9,600,000 (GBP)
Funding ID MC_PC_12027 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2014 
End 12/2015
 
Description UK Biobank Imaging Full Funding
Amount £32,000,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2016 
End 04/2022
 
Description UK Centre of Excellence for Musculoskeletal Health and Work
Amount £1,400,000 (GBP)
Organisation Arthritis Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2014 
End 11/2019
 
Description University Unit Capital Equipment Award
Amount £118,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2014
 
Description University Unit Partnership Grants: Epigenetic processes and the developmental origins of health and disease
Amount £841,392 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 09/2013 
End 08/2018
 
Description Wellcome Trust Collaborative Award
Amount £1,600,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2018 
End 09/2023
 
Title Batman 
Description Bayesian analysis of epigenome-wide methylation 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2014 
Provided To Others? Yes  
Impact Bayesian analysis of epigenome-wide methylation 
 
Title Epidemiology of Sporting Injuries 
Description Sporting injury database for elite championship professional soccer club. 
Type Of Material Biological samples 
Provided To Others? No  
Impact Decline in serious injury incidence; promotion to premiership expected. 
 
Title Health Conversation Skills 
Description Peer-led behaviour change intervention package 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2017 
Provided To Others? Yes  
Impact New Zealand, South Africa, India, Australia Modification of dietary pattern and reduction of adiposity 
 
Title Healthy conversation skills 
Description Peer-led behavioural package to enhance optimal nutritional choices among young women of childbearing age. 
Type Of Material Improvements to research infrastructure 
Year Produced 2011 
Provided To Others? Yes  
Impact Worldwide utilisation of behaviour change package. 
 
Title Hertfordshire Cohort Study 
Description Cohort Study 
Type Of Material Biological samples 
Year Produced 2006 
Provided To Others? Yes  
Impact Papers 
 
Title Hertfordshire Cohort Study 
Description Range of phenotypic data, DNA and posterity blood samples. 
Type Of Material Biological samples 
Year Produced 2006 
Provided To Others? Yes  
Impact Numerous publications (see list for details). 
 
Title High resolution peripheral quantitative computed tomography 
Description Obtains virtual bone biopsy 
Type Of Material Improvements to research infrastructure 
Year Produced 2014 
Provided To Others? Yes  
Impact Obtains virtual bone biopsy 
 
Title Hipmorph 
Description Automated assessment of hip OA 
Type Of Material Improvements to research infrastructure 
Year Produced 2014 
Provided To Others? Yes  
Impact Automated assessment of hip OA 
 
Title Kneemorph 
Description Automated system for evaluation of radiographic knee OA. 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact Reproducible severity grading of osteoarthritis. 
 
Title Novel seasonal adjustment for vitamin D concentrations 
Description Novel method for adjusting the vitamin D concentrations for season, independent of assays used. 
Type Of Material Model of mechanisms or symptoms - human 
Provided To Others? No  
Impact Tracking of 25-hydroxyvitamin D status during pregnancy: the importance of vitamin D supplementation. Moon RJ, Crozier SR, Dennison EM, Davies JH, Robinson SM, Inskip HM, Godfrey KM, Cooper C, Harvey NC. Am J Clin Nutr. 2015 Nov;102(5):1081-7. doi: 10.3945/ajcn.115.115295. 
 
Title SWS Data and samples 
Description Large collection of data and samples from women and children in the Southampton Women's Survey 
Type Of Material Biological samples 
Year Produced 2006 
Provided To Others? Yes  
Impact All the SWS publications. Further grant funding for research within the SWS and for interventions arising out of it. 
 
Description ALPHABET 
Organisation Erasmus University Rotterdam
Country Netherlands 
Sector Academic/University 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description ALPHABET 
Organisation National Institute of Health and Medical Research (INSERM)
Department Center for Epidemiological and Bio Statistics Research at Sorbonne
Country France 
Sector Public 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description ALPHABET 
Organisation University College Dublin
Department School of Physics
Country Ireland 
Sector Academic/University 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description ALPHABET 
Organisation University College Dublin
Country Ireland 
Sector Academic/University 
PI Contribution WP5, bone outcomes
Collaborator Contribution Consortium
Impact Ongoing
Start Year 2017
 
Description ALPHABET 
Organisation University of Bristol
Department Biomedical Research Unit in Nutrition, Diet and Lifestyle
Country United Kingdom 
Sector Hospitals 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description ALPHABET 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution WP5, bone outcomes
Collaborator Contribution Consortium
Impact Ongoing
Start Year 2017
 
Description ALPHABET 
Organisation University of South Carolina
Department Arnold School of Public Health
Country United States 
Sector Academic/University 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description ALSPAC placenta 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Placental determinants of bone mass
Collaborator Contribution Placental determinants of bone mass
Impact Ongoing
Start Year 2013
 
Description ARUK MAVIDOS collaboration 
Organisation University College Cork
Country Ireland 
Sector Academic/University 
PI Contribution Scientific collaboration
Collaborator Contribution Scientific collaboration
Impact 3 papers
Start Year 2013
 
Description ARUK MAVIDOS collaboration 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution DXA Lead
Collaborator Contribution Other imaging
Impact 1 paper
Start Year 2014
 
Description ARUK/MRC Centre of Excellence in Work and Musculoskeletal Disorders 
Organisation University of Liverpool
Department School of Medicine Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution Research collaboration
Collaborator Contribution Research collaboration
Impact PhD students
Start Year 2015
 
Description ARUK/MRC Centre of Excellence in Work and Musculoskeletal Health 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution Research collaboration
Collaborator Contribution Research collaboration
Impact PhD students
Start Year 2015
 
Description ARUK/MRC Centre of Excellence in Work and Musculoskeletal Health 
Organisation University of Oxford
Department School of Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Research collaboration
Collaborator Contribution Research collaboration
Impact PhD students
Start Year 2015
 
Description AUGMENT UK Biobank collaboration 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution AUGMENT UK Biobank collaboration
Collaborator Contribution AUGMENT UK Biobank collaboration
Impact AUGMENT UK Biobank collaboration
Start Year 2017
 
Description AUGMENT UK Biobank collaboration 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution AUGMENT UK Biobank collaboration
Collaborator Contribution AUGMENT UK Biobank collaboration
Impact AUGMENT UK Biobank collaboration
Start Year 2017
 
Description CPRD 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution UK Osteoporosis Epidemiology
Collaborator Contribution UK Osteoporosis Epidemiology
Impact UK Osteoporosis Epidemiology
Start Year 2014
 
Description Danish Population Registry 
Organisation University of Southern Denmark
Country Denmark 
Sector Academic/University 
PI Contribution Scientific collaboration
Collaborator Contribution Scientific collaboration
Impact 2 papers
Start Year 2013
 
Description Danish Population Registry 
Organisation University of Southern Denmark
Country Denmark 
Sector Academic/University 
PI Contribution Scientific collaboration
Collaborator Contribution Scientific collaboration
Impact 2 papers
Start Year 2013
 
Description EPOSA 
Organisation Free University of Amsterdam
Country Netherlands 
Sector Academic/University 
PI Contribution Collaborative science.
Collaborator Contribution Collaborative science.
Impact 5 papers
Start Year 2013
 
Description EU EarlyNutrition 
Organisation Ludwig Maximilian University of Munich (LMU Munich)
Department University Clinic of Munich
Country Germany 
Sector Academic/University 
PI Contribution Work package leadership
Collaborator Contribution Overall collaboration management
Impact 1: Moon RJ, Crozier SR, Dennison EM, Davies JH, Robinson SM, Inskip HM, Godfrey KM, Cooper C, Harvey NC. Tracking of 25-hydroxyvitamin D status during pregnancy: the importance of vitamin D supplementation. Am J Clin Nutr. 2015 Nov;102(5):1081-7. doi: 10.3945/ajcn.115.115295. Epub 2015 Sep 23. PubMed PMID: 26399867; PubMed Central PMCID: PMC4634223. 2: Vogel C, Parsons C, Godfrey K, Robinson S, Harvey NC, Inskip H, Cooper C, Baird J. Greater access to fast-food outlets is associated with poorer bone health in young children. Osteoporos Int. 2015 Oct 12. [Epub ahead of print] PubMed PMID: 26458387. 3: Moon RJ, Harvey NC, Cooper C. ENDOCRINOLOGY IN PREGNANCY: Influence of maternal vitamin D status on obstetric outcomes and the fetal skeleton. Eur J Endocrinol. 2015 Aug;173(2):R69-83. doi: 10.1530/EJE-14-0826. Epub 2015 Apr 10. Review. PubMed PMID: 25862787. 4: Cleal JK, Day PE, Simner CL, Barton SJ, Mahon PA, Inskip HM, Godfrey KM, Hanson MA, Cooper C, Lewis RM, Harvey NC; SWS Study Group. Placental amino acid transport may be regulated by maternal vitamin D and vitamin D-binding protein: results from the Southampton Women's Survey. Br J Nutr. 2015 Jun 28;113(12):1903-10. doi: 10.1017/S0007114515001178. Epub 2015 May 5. PubMed PMID: 25940599; PubMed Central PMCID: PMC4498463. 5: Moon RJ, Cole ZA, Crozier SR, Curtis EM, Davies JH, Gregson CL, Robinson SM, Dennison EM, Godfrey KM, Inskip HM, Cooper C, Harvey NC; Southampton Women's Survey Study Group. Longitudinal changes in lean mass predict pQCT measures of tibial geometry and mineralisation at 6-7 years. Bone. 2015 Jun;75:105-10. doi: 10.1016/j.bone.2015.02.015. Epub 2015 Feb 20. PubMed PMID: 25703480; PubMed Central PMCID: PMC4556067. 6: Moon RJ, Harvey NC, Davies JH, Cooper C. Vitamin D and bone development. Osteoporos Int. 2015 Apr;26(4):1449-51. doi: 10.1007/s00198-014-2976-y. Epub 2014 Dec 2. PubMed PMID: 25448839. 7: Robinson SM, Crozier SR, Harvey NC, Barton BD, Law CM, Godfrey KM, Cooper C, Inskip HM. Modifiable early-life risk factors for childhood adiposity and overweight: an analysis of their combined impact and potential for prevention. Am J Clin Nutr. 2015 Feb;101(2):368-75. doi: 10.3945/ajcn.114.094268. Epub 2014 Dec 3. PubMed PMID: 25646335; PubMed Central PMCID: PMC4307207. 8: Moon RJ, Harvey NC, Davies JH, Cooper C. Vitamin D and skeletal health in infancy and childhood. Osteoporos Int. 2014 Dec;25(12):2673-84. doi: 10.1007/s00198-014-2783-5. Epub 2014 Aug 20. PubMed PMID: 25138259; PubMed Central PMCID: PMC4224585. 9: Harvey N, Dennison E, Cooper C. Osteoporosis: a lifecourse approach. J Bone Miner Res. 2014 Sep;29(9):1917-25. doi: 10.1002/jbmr.2286. Review. PubMed PMID: 24861883. 10: Harvey NC, Holroyd C, Ntani G, Javaid K, Cooper P, Moon R, Cole Z, Tinati T, Godfrey K, Dennison E, Bishop NJ, Baird J, Cooper C. Vitamin D supplementation in pregnancy: a systematic review. Health Technol Assess. 2014 Jul;18(45):1-190. doi: 10.3310/hta18450. Review. PubMed PMID: 25025896; PubMed Central PMCID: PMC4124722. 11: Curtis EM, Moon RJ, Dennison EM, Harvey NC. Prenatal calcium and vitamin D intake, and bone mass in later life. Curr Osteoporos Rep. 2014 Jun;12(2):194-204. doi: 10.1007/s11914-014-0210-7. Review. PubMed PMID: 24740166. 12: de Jongh RT, Crozier SR, D'Angelo S, Pike KC, Roberts G, Lucas JS, Inskip H, Godfrey KM, Cooper C, Harvey NC; Southampton Women's Survey Study Group. Maternal 25-hydroxyvitamin D levels in relation to offspring respiratory symptoms and infections. Eur Respir J. 2014 Apr;43(4):1181-3. doi: 10.1183/09031936.00116913. Epub 2013 Dec 12. PubMed PMID: 24337044; PubMed Central PMCID: PMC3973533. 13: Harvey NC, Cooper C. Vitamin D status and ill health. Lancet Diabetes Endocrinol. 2014 Apr;2(4):e9. doi: 10.1016/S2213-8587(14)70045-2. PubMed PMID: 24703059.
Start Year 2012
 
Description EULAR Centre of Excellence in Rheumatology 
Organisation University Hospital Southampton NHS Foundation Trust
Country United Kingdom 
Sector Hospitals 
PI Contribution Enhanced collaboration
Collaborator Contribution Enhanced collaboration
Impact Various publications.
Start Year 2010
 
Description Epidemiology Maastricht 
Organisation Maastricht University (UM)
Country Netherlands 
Sector Academic/University 
PI Contribution Epidemiology of fractures in UK
Collaborator Contribution Epidemiology of fractures in UK
Impact Ongoing
Start Year 2014
 
Description Epidemiology Utrecht 
Organisation Utrecht University
Country Netherlands 
Sector Academic/University 
PI Contribution Epidemiology of fractures in UK
Collaborator Contribution Epidemiology, medication use, mortality
Impact Ongoing
Start Year 2014
 
Description Fracture Risk Assessment 
Organisation University of Sheffield
Country United Kingdom 
Sector Academic/University 
PI Contribution Fracture Risk Assessment
Collaborator Contribution Fracture Risk Assessment
Impact Fracture Risk Assessment
Start Year 2014
 
Description Genetic Epidemiology of type 2 diabetes mellitus 
Organisation University of Cambridge
Department Department of Clinical Biochemistry
Country United Kingdom 
Sector Academic/University 
PI Contribution Contribution of anonymised phenotypic data; statistical expertise
Impact Publication. PubMed ID: 17019603
Start Year 2006
 
Description HR pQCT 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution Inflammatory disease, bone erosion
Collaborator Contribution Inflammatory disease, bone erosion
Impact Inflammatory disease, bone erosion
Start Year 2014
 
Description Hertfordshire Physical Activity Intervention Trial (HPAT) 
Organisation University of Cambridge
Department MRC Epidemiology Unit
Country United Kingdom 
Sector Multiple 
PI Contribution Contribution of anonymised phenotypic data
Impact Publications. Pubmed ID: 19545359
Start Year 2006
 
Description IOF Barcelona 
Organisation Autonomous University of Barcelona (UAB)
Country Spain 
Sector Academic/University 
PI Contribution Scientific collaboration
Collaborator Contribution Scientific collaboration
Impact 3 papers
Start Year 2014
 
Description IOF vitamin D 
Organisation University of Florence
Department Department of Internal Medicine
Country Italy 
Sector Academic/University 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Rizzoli R et al. CMRO 2013;29:1-9.
Start Year 2011
 
Description IOF vitamin D 
Organisation University of Leuven
Department Centre for Metabolic Bone Diseases
Country Belgium 
Sector Academic/University 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Rizzoli R et al. CMRO 2013;29:1-9.
Start Year 2011
 
Description LPIN1 genotype and diet 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Contribution of anonymised phenotypic data
Impact Publications. Pubmed ID: 18591397
Start Year 2007
 
Description LPIN1 genotype and diet 
Organisation University of Cambridge
Department MRC Epidemiology Unit
Country United Kingdom 
Sector Multiple 
PI Contribution Contribution of anonymised phenotypic data
Impact Publications. Pubmed ID: 18591397
Start Year 2007
 
Description MAVIDOS 
Organisation Medical Research Council (MRC)
Country United Kingdom 
Sector Academic/University 
PI Contribution Scientific collaboration
Collaborator Contribution Scientific collaboration
Impact 2 abstracts
Start Year 2013
 
Description MAVIDOS Childhood Follow up 
Organisation University of Sheffield
Country United Kingdom 
Sector Academic/University 
PI Contribution Recruitment to MAVIDOS 6 year follow-up in Sheffield
Collaborator Contribution Recruitment to MAVIDOS six-year follow-up in Sheffield
Impact N/A
Start Year 2016
 
Description MAVIDOS Childhood Follow-up Oxford 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Recruitment of children to MAVIDOS six-year follow-up in Oxford
Collaborator Contribution Recruitment of children to MAVIDOS six-year follow-up in Oxford
Impact N/A
Start Year 2016
 
Description MAVIDOS Oxford CVD 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Vitamin D in pregnancy and offspring cardiac structure and function
Collaborator Contribution Vitamin D in pregnancy and offspring cardiac structure and function
Impact Ongoing
Start Year 2015
 
Description Metabolic syndrome in HCS 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution Contribution of anonymised phenotypic data; statistical expertise
Impact Multiple abstracts in this field
 
Description ODIN 
Organisation University College Cork
Country Ireland 
Sector Academic/University 
PI Contribution Scientific collaboration
Collaborator Contribution Scientific collaboration
Impact 3 papers
Start Year 2013
 
Description Osteoarthritis: Health Economics 
Organisation Cedars-Sinai Medical Center
Country United States 
Sector Hospitals 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press.
Start Year 2011
 
Description Osteoarthritis: Health Economics 
Organisation Diakonhjemmet Hospital
Department Department of Rheumatology
Country Norway 
Sector Hospitals 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press.
Start Year 2011
 
Description Osteoarthritis: Health Economics 
Organisation Northwestern University
Department Feinberg School of Medicine
Country United States 
Sector Academic/University 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press.
Start Year 2011
 
Description Osteoarthritis: Health Economics 
Organisation Royal North Shore Hospital and Kolling Institute
Country Australia 
Sector Hospitals 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press.
Start Year 2011
 
Description Osteoarthritis: Health Economics 
Organisation University of Lorraine
Country France 
Sector Academic/University 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press.
Start Year 2011
 
Description Osteoarthritis: Health Economics 
Organisation University of Maryland
Department Division of Rheumatology & Clinical Immunology
Country United States 
Sector Academic/University 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press.
Start Year 2011
 
Description Osteoarthritis: Health Economics 
Organisation University of Ottawa
Department Faculty of Medicine
Country Canada 
Sector Academic/University 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press.
Start Year 2011
 
Description Osteoarthritis: Health Economics 
Organisation VU University Medical Center
Department Department of Epidemiology and Biostatistics
Country Netherlands 
Sector Academic/University 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press.
Start Year 2011
 
Description Physical activity 
Organisation University of Cambridge
Department MRC Epidemiology Unit
Country United Kingdom 
Sector Multiple 
PI Contribution Epidemiological data
Collaborator Contribution Epidemiological data
Impact Collings PJ et al. Am J Clin Nutr 2013;97: 1020-8. Harvey NC et al. Osteoporos Int 2012;23:121-30. Hesketh KR et al. BMC Public Health 2013;13:924. McMinn AM et al. Int J Behav Nutr Phys Act 2009;6:81.
Start Year 2011
 
Description Relationship of aldosterone with cortisol and blood pressure 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Contribution of anonymised phenotypic data
Impact Publications. Pubmed ID: 19380612
Start Year 2006
 
Description Shape Modelling 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Hip and knee shape modelling for osteoarthritis
Collaborator Contribution Hip and knee shape modelling for osteoarthritis
Impact Hip and knee shape modelling for osteoarthritis
Start Year 2014
 
Description UK Biobank 
Organisation University of Oxford
Department School of Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Research collaboration
Collaborator Contribution Research collaboration
Impact Emergent analysis of body composition and cardiovascular function in UK Biobank
Start Year 2015
 
Description UK Biobank 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution DXA Lead
Collaborator Contribution Other imaging
Impact 1 paper
Start Year 2014
 
Description UK Biobank Aberdeen 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Active shape modelling of joints- epidemiology
Collaborator Contribution Active shape modelling of joints- modelling
Impact Ongoing
Start Year 2015
 
Description UK Biobank Bristol 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Determinants of bone mass and fracture risk
Collaborator Contribution Determinants of bone mass and fracture risk
Impact Ongoing
Start Year 2016
 
Description UK Biobank Sheffield 
Organisation University of Sheffield
Country United Kingdom 
Sector Academic/University 
PI Contribution DXA pixel mapping- epidemiology and UKB
Collaborator Contribution DXA pixel mapping- technical expertise
Impact Ongoing
Start Year 2015
 
Description UKB CVD OP 
Organisation Queen Mary University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution UK Biobank: Associations between BMD, fracture and cardiovascular disease
Collaborator Contribution UK Biobank: Associations between BMD, fracture and cardiovascular disease
Impact UK Biobank: Associations between BMD, fracture and cardiovascular disease
Start Year 2014
 
Description VIBE 
Organisation University of Bristol
Department MRC Integrative Epidemiology Unit
Country United Kingdom 
Sector Academic/University 
PI Contribution Scientific collaboration
Collaborator Contribution Scientific collaboration
Impact 2 abstracts
Start Year 2013
 
Description WHO Clinical Consortium on Health Ageing 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution Contribution to World Report on Ageing and Health, and project to operationalise concept of intrinsic capacity
Collaborator Contribution Organisation of WHO workshop on intrinsic capacity
Impact WHO Global Report on Ageing and Health
Start Year 2016
 
Title Healthy Conversation Skill Behavioural Package 
Description Peer led intervention package for young women aiming to optimize nutrition and physical activity 
Type Of Technology Webtool/Application 
Year Produced 2017 
Open Source License? Yes  
Impact Multiple use in South Africa, New Zealand, Malaysia, Singapore 
 
Description 2017 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases, Florence 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Scientific Committee Chairperson for this event in Florence, Italy on 15th June 2017. The event was captured online, twitter, facebook and email
Year(s) Of Engagement Activity 2017
 
Description A blog welcoming Professor Cyrus Cooper to their new trustee 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact The Medical Research Foundation added to their blog to welcome Cyrus Cooper as their new trustee. Cyrus was nominated by the MRC and his term will be until 2020
Year(s) Of Engagement Activity 2017
 
Description A press release issued for a paper which was published in the University of Southampton News and Medicalxpress 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact Press release on 'Relationships between markers of inflammation and muscle mass, strength and function: Findings from the Hertfordshire Cohort Study.
Year(s) Of Engagement Activity 2017
 
Description ASBMR Annual Conference, Atlanta, USA - Plenary Lectures 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact ASBMR Annual Conference, Atlanta, USA - Plenary Lectures
Year(s) Of Engagement Activity 2016
 
Description Arthritis Research UK Pain Workshop, Wellcome Trust, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Arthritis Research UK Pain Workshop, Wellcome Trust, London
Year(s) Of Engagement Activity 2016
 
Description Article in National newspaper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The Guardian newspaper published an article entitled 'Murder Mystery to DNAL researchers bring science to life in schools.' The article covered the benefits of introducing school pupils to science in a laboratory environment.
Year(s) Of Engagement Activity 2017
 
Description Article published on two websites 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact This article attracted some media attention and appeared on two websites and the University of Southampton enews. The articles were entitled 'Poorer health influences muscle strength in later life'.
Year(s) Of Engagement Activity 2017
 
Description Article submitted for the 8th December edition of the Friday blog 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Karen Walker-Bone and Cyrus Cooper submitted an article entitled 'Good work is good for us'.
Year(s) Of Engagement Activity 2017
 
Description Articles on MAVIDOS findings appeared on website articles and facebook 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Articles on MAVIDOS findings appeared on the University of Southampton website, World News website; Publicnow.com. It was also mentioned on a number of Facebook pages including, University of Southampton; International Osteoporosis Foundation and Resilient Bones.
Year(s) Of Engagement Activity 2017
 
Description BMFMS, Amsterdam 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact BMFMS, Amsterdam
Year(s) Of Engagement Activity 2016
 
Description Blog for the University of Southampton 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Regular broadcast while giving a talk in Geneva. It was one week after the general election. It made Cyrus more aware of the impact the election and Brexit would have on the work we do
Year(s) Of Engagement Activity 2017
 
Description Blog on global outreach of the research of the MRC LEU 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Stimulating increased interest in research globally in the research of the MRC.
Year(s) Of Engagement Activity 2017
 
Description British Orthopedic Research Society Keynote lecture (EMD) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact British Orthopedic Research Society Keynote lecture
Year(s) Of Engagement Activity 2017
 
Description CCA Meeting, Geneva - invited lecture 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact CCA Meeting, Geneva - invited lecture
Year(s) Of Engagement Activity 2016
 
Description Conference IOF Florence March 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The members of the Committee of Scientific Advisors of the International Osteoporosis Foundation (IOF) and the Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) are developing a very exciting Congress' scientific programme that will bring together the world's best in the field of musculoskeletal health and disease.

We really hope to welcome you in Krakow, Poland and that this Congress will move the field one step forward on all fronts; from new understanding of bone metabolism and pathology, to new strategies and options in prevention, diagnosis and treatment.
Year(s) Of Engagement Activity 2017
 
Description Daily Mail vitamin D article 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Interview on vitamin D to inform Daily Mail research
Year(s) Of Engagement Activity 2017
 
Description Donation from Wessex Heartbeat of £200,000 in the LifeLab programme to help region's chldren lead a healthier life 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Undergraduate students
Results and Impact News of the donation was on the University of Southampton website under medicine and lifelab news, daily echo website and newspaper, and deepsouth media.
Year(s) Of Engagement Activity 2017
 
Description ECTS Conference, Rome. Keynote Lecture 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact ECTS Conference, Rome. Keynote Lecture
Year(s) Of Engagement Activity 2016
 
Description ECTS, Salzburg 13-16 May 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact ECTS, Salzburg 13-16 May
Year(s) Of Engagement Activity 2017
 
Description ESCEO Working Groups, Geneva - Invited Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Vitamin D Meeting, London - Invited Lecture
Year(s) Of Engagement Activity 2016
 
Description ESICON Congress, New Delhi. Plenary Lecture 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact ESICON Congress, New Delhi. Plenary Lecture
Year(s) Of Engagement Activity 2016
 
Description Enews email University of Southampton, Faculty of Medicine and Daily Echo, Deccan Chronical and Medical Xpress 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Sarah El Heis and Cyrus Cooper submitted paper entitled 'Maternal Stress and psychological distress preconception: association with offspring atopic eczema at age 12 months' to University of Southampton Faculty of Medicine and local newspapers. This paper received media attention from the University and the Daily Echo.
Year(s) Of Engagement Activity 2017
 
Description Enews, University of Southampton: QQR renewal; and David Barker Research Prize (CC) 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact Enews, University of Southampton: QQR renewal; and David Barker Research Prize awarded to CC.
Year(s) Of Engagement Activity 2015
 
Description Expert Opinion 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Nick Harvey answered questions from the Daily Mail regarding Vitamin D formulations
Year(s) Of Engagement Activity 2017
 
Description Faculty of Medicine eNews Blog: CC 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact Faculty of Medicine eNews blog: CC
Year(s) Of Engagement Activity 2016
 
Description ICCBH presentation (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Lecture on children's bone health
Year(s) Of Engagement Activity 2017
 
Description ICFSR Annual Congress, Philadelphia, Keynote Lecture 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact ICFSR Annual Congress, Philadelphia, Keynote Lecture
Year(s) Of Engagement Activity 2016
 
Description ICFSR, Barcelona 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact ICFSR, Barcelona
Year(s) Of Engagement Activity 2017
 
Description IOF CTF Webinar (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact IOF CTF Webinar
Year(s) Of Engagement Activity 2018
 
Description IOF ESCEO WCO, Florence 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact IOF ESCEO WCO, Florence
Year(s) Of Engagement Activity 2016
 
Description IOF ESCEO meeting, Geneva 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact IOF ESCEO meeting, Geneva
Year(s) Of Engagement Activity 2017
 
Description IOF Meeting, Geneva - Invited Lecture 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact IOF Meeting, Geneva - Invited Lecture
Year(s) Of Engagement Activity 2016
 
Description IOF Regionals, Singapore, Plenary lectures and chairing commitments 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact IOF Regionals, Singapore, Plenary lectures and chairing commitments
Year(s) Of Engagement Activity 2016
 
Description IOF WCO Florence ESCEO Symposium (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Lecture on imminent fracture risk in scientific symposium
Year(s) Of Engagement Activity 2017
 
Description IOF/ ESCEO working group OA (EMD) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact IOF/ ESCEO working group OA (EMD)
Year(s) Of Engagement Activity 2017
 
Description ISCD Conference, Galway, Ireland, Plenary lectures and chairing 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact ECTS Conference, Rome. Keynote Lecture
Year(s) Of Engagement Activity 2016
 
Description International Award for Publishing Excellence 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The authors received this international award for a paper that they published.
Year(s) Of Engagement Activity 2016
 
Description Invited ASBMR Webinar (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited ASBMR Webinar (NCH)
Year(s) Of Engagement Activity 2018
 
Description Invited lecture (CC): 24th Annual Gregory Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Invited presentation on vitamin D in pregnancy, including MAVIDOS
Year(s) Of Engagement Activity 2016
 
Description Invited lecture (CC): British Rheumatology Society 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited presentation on vitamin D, including MAVIDOS.
Year(s) Of Engagement Activity 2016
 
Description Invited lecture (CC): ECTS, Rome 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited lecture on vitamin D in pregnancy, including MAVIDOS
Year(s) Of Engagement Activity 2016
 
Description Invited lecture (CC): ISCD, Galway, Ireland 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited lecture on vitamin D in pregnancy, including MAVIDOS
Year(s) Of Engagement Activity 2016
 
Description Invited lecture (CC): Vitamin D meeting, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited presentation on vitamin D in pregnancy, including MAVIDOS
Year(s) Of Engagement Activity 2016
 
Description Invited lectures (CC): IOF-ESCEO World Congress on Osteoporosis, Malaga 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited lectures on vitamin D in pregnancy, including MAVIDOS
Year(s) Of Engagement Activity 2016
 
Description Invited plenary presentation, Mellanby Bone Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited plenary presentation, Mellanby Bone Conference
Year(s) Of Engagement Activity 2017
 
Description Invited plenary presentation, UK Biobank Annual Conference (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited plenary presentation, UK Biobank Annual Conference (NCH)
Year(s) Of Engagement Activity 2017
 
Description Invited talks 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Participants in your research and patient groups
Results and Impact Multiple major national and international meetings

Press conferences, scientific collaborations, grant funding and publications
Year(s) Of Engagement Activity 2006,2007,2008,2009,2010
 
Description LifeLab Meet the Scientist Training Day 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Both Becca Moon and Janis Baird attended the all day training session on LifeLab Meet the Scientist
Year(s) Of Engagement Activity 2017
 
Description LifeLab Presentation 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Dr Rebecca Moon gave a LifeLab Meet the Scientist presentation to 23 year 9 students from Petersfield School.
Year(s) Of Engagement Activity 2017
 
Description Live television interview on "That Solent" (NCH) 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Media (as a channel to the public)
Results and Impact Live television interview covering MAVIDOS study and involvement in UK Biobank.
Year(s) Of Engagement Activity 2016
 
Description MRC Festival of Medical Research, Southampton 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact MRC Festival of Science, Southampton
Year(s) Of Engagement Activity 2016
 
Description Meeting of the MRC LEU Research Review Panel, 5th July 2017 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Meeting of the MRC LEU Research Review Panel. This meeting took place at the MRC LEU and was chaired by Councillor Ivan White and presentations were given by Councillor Sarah Bogle, about her visit to LifeLab, Mary Barker on EACh-B and Elaine Dennison on The Hertfordshire Integration Study.
Year(s) Of Engagement Activity 2017
 
Description Menopause Conference, Prague - Plenary Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Menopause Conference, Prague - Plenary Lecture
Year(s) Of Engagement Activity 2016
 
Description Multiple press releases and media coverage on MAVIDOS vitamin D paper published in the Lancet Diabetes & Endocrinology, 1 March 2016 [CC, NCH et al] 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Large media coverage on paper published in the Lancet Diabetes and Endocrinology. Cooper C, Harvey N et al. Maternal gestational vitamin D supplementation and offspring bone health (MAVIDOS): a multicentre, double-blind, randomised placebo-controlled trial.
Year(s) Of Engagement Activity 2016
 
Description New Forest Rotary Club Donation 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact New Forest Rotary Club enabled all Hounsdown School's Year 9 pupils to take part in the Lifelab programme thanks to a grant of £1,300 which funded the transport from school to the University of Southampton's LifeLab at the Biomedical Research Centre. The children thoroughly enjoyed the experience.
Year(s) Of Engagement Activity 2017
 
Description New Twitter Account 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Elizabeth Curtis sent an email to MRC LEU staff letting them know that the MRC LEU now has its own twitter account
Year(s) Of Engagement Activity 2017
 
Description Newsletter Hertfordshire 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Developed a newsletter for participants in the Hertfordshire Cohort Study

Enables participants to be updated on findings from the latest research as well as informed on forthcoming studies
Year(s) Of Engagement Activity 2008
 
Description Novel technique helps identify diabetic patients at risk of bone fracture (ME) 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Various media coverage on the legions and virtual bone biopsy stories.
Year(s) Of Engagement Activity 2016
 
Description Osteoporosis Dorset (EMD) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Osteoporosis Dorset
Year(s) Of Engagement Activity 2017
 
Description Osteoporosis Summit Meeting, Armenia, Keynote Lectures and Government Advisory Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Osteoporosis Summit Meeting, Armenia, Keynote Lectures and Government Advisory Meeting
Year(s) Of Engagement Activity 2016
 
Description Osteoporosis Update Meeting, Bournemouth. Invited Lecture 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Osteoporosis Update Meeting, Bournemouth. Invited Lecture
Year(s) Of Engagement Activity 2016
 
Description Paper published on various websites, facebook and twitter 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Paper entitled 'Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis, submitted for publication in Nature Genetics by N Harvey and C Cooper. This paper received a great deal of attention from around the world on various websites, facebook and twitter.
Year(s) Of Engagement Activity 2017
 
Description Paper receiving much media atttention on various websites, facebook and twitter 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis, printed in Nature Genetics and receiving international attention
Year(s) Of Engagement Activity 2017
 
Description Plenary invited presentation Managing Osteoporosis Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Plenary invited presentation Managing Osteoporosis Conference
Year(s) Of Engagement Activity 2017
 
Description Plenary invited presentation at DOHAD World Congress (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Plenary invited presentation at DOHAD World Congress
Year(s) Of Engagement Activity 2017
 
Description Plenary presentation, International Conference on Children's Bone Health, Wurzburg (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Plenary presentation, International Conference on Children's Bone Health, Wurzburg (NCH)
Year(s) Of Engagement Activity 2017
 
Description Presentation at American Society for Bone and Mineral Research Annual Scientific meeting (EMC) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at American Society for Bone and Mineral Research Annual Scientific meeting (EMC)
Year(s) Of Engagement Activity 2017
 
Description Presentation at American Society for Bone and Mineral Research Annual Scientific meeting (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at American Society for Bone and Mineral Research Annual Scientific meeting (NCH)
Year(s) Of Engagement Activity 2017
 
Description Presentation at Association of Physicians Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation at Association of Physicians Meeting
Year(s) Of Engagement Activity 2017
 
Description Presentation at DOHAD World Congress (EMC) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at DOHAD World Congress (EMC)
Year(s) Of Engagement Activity 2017
 
Description Presentation at UK Association of Physicians Meeting (EMC) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation at Association of Physicians Meeting
Year(s) Of Engagement Activity 2017
 
Description Presentation at World Congress in Osteoporosis (EMC) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at World Congress in Osteoporosis (EMC)
Year(s) Of Engagement Activity 2017
 
Description Presentation at World Congress in Osteoporosis (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at World Congress in Osteoporosis (NCH)
Year(s) Of Engagement Activity 2017
 
Description Presentation at the Guernsey Support Group of the NOS on 25th May 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Face to face invited speaker, presentation given and well accepted
Year(s) Of Engagement Activity 2017
 
Description Presentation given by Professor Nick Harvey 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Presentation given by Nick Harvey to the South Wilts Coeliac Group in Salisbury.
Year(s) Of Engagement Activity 2016
 
Description Presentation of MAVIDOS at the visit of HRH Duchess of Cornwall to University of Southampton 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Presentation of MAVIDOS study results to HRH to Duchess of Cornwall and visiting officials. Visit captured on national television.
Year(s) Of Engagement Activity 2016
 
Description Presented at the Australian and New Zealand Society for Sarcopenia and Fraility Research 2107 Annual Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper presented at the Annual Meeting on Sarcopenia and Physical Fraility: conceptual frameworks and descriptive epidemiology. He also took part in Meet the Professor Breakfast. The topic was Osteoporotic Fracture: Recent advances in risk of assessment, prevention and treatment at the bone muscle interface.
Year(s) Of Engagement Activity 2017
 
Description Press Release 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Media (as a channel to the public)
Results and Impact Press release entitled 'Genes influence response to Vitamin D supplementation in pregnancy was issued by the University of Southampton when this paper relating to the MAVIDOS study was published.
Year(s) Of Engagement Activity 2017
 
Description Press Release of Paper with paper being cited on 4 websites plus social media 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper and Nick Harvey submitted the press release as a result of the publication of the paper 'Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial', in the Lancet, 2017. This was also then cited on 4 websites plus social media.
Year(s) Of Engagement Activity 2017
 
Description Press release entitled "Genes influence response to Vitamin D supplementation in Pregnancy" 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Press release was issued by the University of Southampton on paper by Rebecca Moon when this paper relating to the MAVIDOS study was published. No citings found as yet.
Year(s) Of Engagement Activity 2017
 
Description Press release of paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 'Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial' was published in the Lancet. Following this publication, Nick Harvey and Cyrus Cooper ensured press releases were issued which was then followed by media attention with the paper being cited on 4 websites plus social media.
Year(s) Of Engagement Activity 2017
 
Description Press release; online and newspapers for paper by Sian Robinson and C Cooper et al 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Press release on 'Adult lifetime diet quality and physical performance in older age: Findings from a British birth cohort'. There was a lot of media interest surrounding this publication with at least 15 website and 5 newspaper articles. Cyrus Cooper gave an interview with The Times newspaper, and details of the publication were also mentioned in the University enews.
Year(s) Of Engagement Activity 2017
 
Description Product of development and research for stronger, active bodies: Fortis Net, University of Southampton 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Institute for Life Sciences promotional leaflet: Fortis Net
Year(s) Of Engagement Activity 2016
 
Description Professor Cyrus Cooper's Blog 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Cyrus Cooper wrote his blog on the Global outreach of the research of the MRC LEU. He had recently attended the World Congress in Florence, so his blog covered this event.
Year(s) Of Engagement Activity 2017
 
Description Professor Nick Harvey presented at UK Biobank Annual Meeting, Manchester, 29th June 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Nick Harvey gave a talk entitled "New Insights into bone diseases" during the afternoon session about research opportunity. The event was live streamed on the website.
Year(s) Of Engagement Activity 2017
 
Description Public Meeting Hertfordshire 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Public meeting for participants in the Hertfordshire Cohort Study

Attended by over 700 participants, local dignataries and press, raising the profile of the science, scientists and Medical Research Council as well as providing an opportunity for public engagement and education.
Year(s) Of Engagement Activity 2008
 
Description Publication of paper coinciding with World Obesity Day on 10th October 2017 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Publication of paper 'Worldwide trends in body-mass index, underweight, overweight and obesity from 1975 to 2016: a pooled analysis of 2416 population based measurement studies in 128.9 million children, adolescents and adults' in the Lancet. This was co-authored with Imperial College, London. The paper attracted much media attention.
Year(s) Of Engagement Activity 2017
 
Description RCP Lecture, Uni of Newcastle 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact RCP Lecture, Uni of Newcastle
Year(s) Of Engagement Activity 2016
 
Description Reporting of the findings from paper of Southampton Women's Survey 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact A press release for this paper attracted a lot of media attention with it appearing in local press as well as a number of websites
Year(s) Of Engagement Activity 2017
 
Description Reporting of the findings of a published paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact A press release for this paper attracted quite a lot of media attention with it appearing in local press as well as a number of websites.
Year(s) Of Engagement Activity 2016
 
Description Rheumatology Congress, Paris - Invited Lecture 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Rheumatology Congress, Paris - Invited Lecture
Year(s) Of Engagement Activity 2016
 
Description SWS Newsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Study participants or study members
Results and Impact Southampton Women's Survey newsletter
Year(s) Of Engagement Activity 2017
 
Description SWS Newsletter sent to the House of Commons 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Hazel Inskip and Cyrus Cooper ensured that the SWS newsletter to the Chair of the Health Select Committee in the House of Commons, Dr Sarah Wollaston. Dr Wollaston, MP thanked them for sending the newletter and said it had been received, noted and read with interest.
Year(s) Of Engagement Activity 2017
 
Description School visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Rebecca Moon spoke to 24 year 9 pupils from Noadswood School
Year(s) Of Engagement Activity 2017
 
Description Scientific presentations 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach International
Primary Audience Health professionals
Results and Impact Multiple accepted abstracts presented at major national and international meetings

Press conferences, scientific collaborations, grant funding and publications
Year(s) Of Engagement Activity 2006,2007,2008,2009,2010
 
Description Sian Robinson presented an abstract at the International Conference on Frailty and Sarcopenia. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Sian Robinson presented abstract from 'Adult lifetime diet quality and physical performance in older age: findings from a British born cohort'.
Year(s) Of Engagement Activity 2017
 
Description Talk at Belgian Bone Club, Brussels 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Belgian Bone Club, Brussels
Year(s) Of Engagement Activity 2017
 
Description Ten Topics In Rheumatology - Mtg London Keynote Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Vitamin D Meeting, London - Invited Lecture
Year(s) Of Engagement Activity 2016
 
Description The Duchess of Cornwall, honorary degree, University of Southampton 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact The Duchess of Cornwall was awarded an Honorary Degree at the University of Southampton, 11 February 2016.
Year(s) Of Engagement Activity 2016
 
Description UK Bone Research Society plenary presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact UK BRS debate on early life origins
Year(s) Of Engagement Activity 2017
 
Description University of Southampton News: Tackling Public Health Challenges 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact University of Southampton News: Tackling Public Health Challenges
Year(s) Of Engagement Activity 2016
 
Description University of Southampton Public Lecture Series: The Wellcome Trust, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact University of Southampton Public Lecture Series: The Wellcome Trust, London
Year(s) Of Engagement Activity 2016
 
Description University of Southampton Science and Engineering Day - 18 March 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Members of the MRC LEU staff and one LifeLab member of staff volunteered for this event and helped with hands-on activities produced to showcase the MRC LEU's research.
Year(s) Of Engagement Activity 2017
 
Description University of Southampton Science and Engineering Day 2017 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact 7,000 attended the event and over 400 took part in science/research activities. A number of staff from MRC LEU volunteered to help.
Year(s) Of Engagement Activity 2017
URL https://www.southampton.ac.uk/per/university/festival/science-and-engineering-day.page
 
Description University of Southampton enews congratulated the multi-disciplinary InSTEP Trial Team including the MRC LEU 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact University of Southampton enews congratulated the multi-disciplinary InSTEP Trial Team including from the MRC LEU, Karen Walker-Bone, Cyrus Cooper and Cathy Linaker, which is funded by the NIHR HTA and is undertaking a £330,000 commissioned programme of work to ascertain if it might be feasible to do a randomised controlled trial in order to evaluate a vocational intervention called "Individual Placement and Support2 for people unemployed as a result of chronic pain". The team have initiated a pilot trial and recruited their first patient.
Year(s) Of Engagement Activity 2017
 
Description Various Tweets 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A number of tweets were made as a result of the paper entitled "Improving recruitment to clinical trials during pregnancy: a mixed methods investigation" being accepted for publication.
Year(s) Of Engagement Activity 2017
 
Description Vitamin D Meeting, London - Invited Lecture 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Vitamin D Meeting, London - Invited Lecture
Year(s) Of Engagement Activity 2016
 
Description WCO invited lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited lecture
Year(s) Of Engagement Activity 2017
 
Description WHO Meeting Geneva - Invited Lecture 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact WHO Meeting Geneva - Invited Lecture
Year(s) Of Engagement Activity 2016
 
Description WHO Meeting Geneva - Invited Lecture 10-11 May 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact WHO Meeting Geneva - Invited Lecture 10-11 May
Year(s) Of Engagement Activity 2017
 
Description Website Hertfordshire 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Recent launch of the Hertfordshire Cohort Study website

Enables participants to be updated on findings from the latest research as well as informed on forthcoming studies
Year(s) Of Engagement Activity 2008
 
Description Workshops presented by Hazel Inskip and Rebecca Moon to year 9 students at St Anne's Catholic School for Girls and Wildern School 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Hazel Inskip presented to 24 year 9 students from St Anne's Catholic School for Girls on 9th June. Rebecca Moon presented to 22 year 9 students from Wildern School on 14th June. Both groups gave good feedback of the session. Kath Woods-Townend sent the monthly update for June giving the running total of school students who have taken part which was 6257 and 1690 for the 2016-2017 academic year.
Year(s) Of Engagement Activity 2017
 
Description World Congress on Osteoporosis, Florence 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 2 plenary lectures; 5 workshops; 1 scientific committee
Year(s) Of Engagement Activity 2017