Centre for Macaques (CFM)

Lead Research Organisation: MRC Harwell

Abstract

Macaques are primates which have similarities to humans in terms of their central nervous system (including the visual system), and their immunology and reproductive systems. This means that they continue to be used in some areas of research where there are no alternative approaches. They are used in basic and applied research within the academic sector in the UK, funded by the major grant-giving bodies.

Technical Summary

The MRC Centre for Macaques is a primate breeding unit established in 2003 to house and breed rhesus macaques, funded by the MRC with support from the Wellcome Trust.
The unit houses about 250 animals, which includes breeding stock and youngsters. The breeding programme is carefully planned so that supply and demand are matched. By maintaining breeding families of macaques at CFM it is not necessary to import animals for UK research and therefore guarantee high husbandry and care standards.
The staff and collaborators of CFM are also engaged in many studies of the behaviour of macaques aimed at not only improving macaques welfare and husbandry standards but informing future primate scientific studies .
Primates are sourced from CFM by UK universities and primate tissue samples are also available for academic and commercial collaborators.

Publications

10 25 50
 
Description Chaired session of the Primate Society if Great Britain Spring Meeting, Canterbury
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact Society guides research on primates in the UK
 
Description Keynote presentation at Primtrain COST Action Meeting, Portugal
Geographic Reach Europe 
Policy Influence Type Influenced training of practitioners or researchers
Impact Title -Automated behaviour analysis of macaques in the home cage and the lab'. This approach has an impact on the welfare of the animals and the perception that the public has of this type of research. The data collection quality is also improved and this allows for fewer animals and experiments to be carried out.
 
Description Management Committee of Cost Action CA15131 - Behavioural Management and Training of Laboratory non-human Primates and Large laboratory Animals (PRIMTRAIN)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact guidance on primate and large laboratory animal training for behavioural studies
 
Description Membership Secretary and Council Member of the Primate Society of Great Britain
Geographic Reach Europe 
Policy Influence Type Membership of a guideline committee
Impact te société acts a fuite for the primate research sector in the UK and interacts/consults/contributes to European wide policies
 
Title C57BL/6N-Ptk7tm1a(EUCOMM)Hmgu/H 
Description Mouse models 
Type Of Material Model of mechanisms or symptoms - mammalian in vivo 
Year Produced 2020 
Provided To Others? Yes  
Impact Facilities Research - Export 
URL http://www.mousebook.org
 
Title C57BL/6NTac-Cdh23ahl+em3H/H 
Description Mouse models 
Type Of Material Model of mechanisms or symptoms - mammalian in vivo 
Year Produced 2020 
Provided To Others? Yes  
Impact Facilities Research - Export 
URL http://www.mousebook.org
 
Title Weekly blood collections for Medimmune and B&K 
Description Macaque blood collected and shipped weekly for our colleagues 
Type Of Material Biological samples 
Year Produced 2019 
Provided To Others? No  
Impact N/A 
 
Title macaque supplied to the University of Newcastle 
Description Rhesus macaques supplied for research projects 
Type Of Material Model of mechanisms or symptoms - mammalian in vivo 
Year Produced 2019 
Provided To Others? No  
Impact Project could not be carried out without the supply 
 
Title tissue collected from 10 animals a supplied to various research institutions 
Description Glen Jeffery (Institute of Opthamology, UCL) - Eyes Demetris Soteropoulos/Gavin Clowry/Stuart Baker (Newcastle University) - Brains and Spinal Cords Caroline Bergmann/Jerome Sallet (Oxford University) - Heads/Brains Immunotec - Oesophagus Public Health England - Brain/Skin/Duodenum/Lymph Nodes/Eyes Kings College London - Blood (from older animals only) 
Type Of Material Biological samples 
Year Produced 2019 
Provided To Others? No  
Impact N/A 
 
Title Macaque Faces. figshare. 
Description dataset 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
Impact available for scientific community to compare data and use for own research purposes 
URL https://doi.org/10.6084/m9.figshare.9862586
 
Description Collaborator presentation at the NC3Rs Primate Welfare Meeting, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Title - Te Macaque Stimulus Set
Year(s) Of Engagement Activity 2019
 
Description Poster presentation at UFAW International Meeting, Bruges, Belgium 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Title - Fight Injuries and Productivity in Rhesus Macaques
Year(s) Of Engagement Activity 2019
 
Description Presentation at the European Federation of Primatology/Primate Society of Great Britain Joint Meeting - Oxford 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Title - Use of Automated Image Analysis to monitor Primates in captivity and in the wild
Year(s) Of Engagement Activity 2019
 
Description Student presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation title - Physiology, cognition and behaviour: a three pronged approach to welfare assessment
Year(s) Of Engagement Activity 2019
 
Description Student presentation at the European Federation of Primatology/Primate Society of Great Britain Joint Meeting, Oxford 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Title - Social tolerance and inhibitory control skills in macaque species
Year(s) Of Engagement Activity 2019
 
Description Student presentation at the European Federation of Primatology/Primate Society of Great Britain Joint Meeting, Oxford 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Title - A study using the animal welfare assessment grid (AWAG) to measure quality of life of captive breeding rhesus macaques at the Medical Research Council Centre for macaques facility
Year(s) Of Engagement Activity 2019
 
Description Student presentation at the NC3Rs Primate Welfare Meeting, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Title - Refining the weaning age of rhesus macaques (Macaca mulatta) destined for neuroscience research
Year(s) Of Engagement Activity 2019
 
Description Student presentation at the NC3Rs Primate Welfare Meeting, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Title - Welfare study using the animal welfare assessment grid to measure quality of life in breeding macaques
Year(s) Of Engagement Activity 2019
 
Description Student presentation at the Primate Society of Great Britain Spring Meeting, Canterbury 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Title - Pilot Study and summer project using the AWAG software to study the welfare of breeding Rhesus Macaques in research
Year(s) Of Engagement Activity 2019
 
Description Talk at Centre of Behaviour and Evolution, Newcastle University 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Title - Automated behaviour analysis of macaques in the home cage and the lab
Year(s) Of Engagement Activity 2019
 
Description Talk at FELASA, Prague, Czech Republic 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Title - Monitoring social relationships in rhesus macaques
Year(s) Of Engagement Activity 2019
 
Description collaborator presentation at the NC3Rs Primate Welfare Meeting London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Title - Telomere dynamics and stress in rhesus macaques
Year(s) Of Engagement Activity 2019