Mental Ageing

Lead Research Organisation: University College London

Abstract

Cognitive capability and emotional wellbeing are essential to quality of life in ageing. Cognitive capability is the foundation for skilled activities of daily living, including learning, remembering, multi-tasking, and forming plans and goals; and is linked to physical health. Emotional wellbeing depends on successful control of anxiety and depression, the most common mental disorders in the general population; it is also important for daily function and physical health, as implied by the UK Government declaration ‘No health without mental health’.
The key goals of this programme over the next five years are to identify how to optimise cognitive function and reduce risk of depression in later life through a life course approach, within three closely related themes:

Capturing mental ageing, including clinically significant cognitive decline and depression

Maintaining mental capability in early old age, emphasising education, work and retirement, and the development of self-organisation and its links to the self-management of health

Links between mental ageing and physical ageing and survival

Technical Summary

This programme brings a life course approach to bear on maintaining quality of later life through promoting cognitive capability and reducing risk of depression. The essence of this approach is to map life course determinants and consequences of cognition and affect; their associations with each other, and their associations with other aspects of health and function through common and sequential causes. Key recent accomplishments include:

Clarifying the pathways through which cognitive development influences adult health: directly for health outcomes closely related to neural systems governing cognition (e.g. affective state, balance and coordination, and reproductive function); through social pathways, primarily education, for preventable chronic physical diseases.

Conducting cross-cohort work demonstrating the impact of adolescent mental health, particularly conduct problems, on a wide range of life chances, from educational and socioeconomic attainment, to social roles such as family formation and citizenship, to health.

Building on our long-term work showing that cognition, as well as affective state, is modifiable in midlife. In the case of cognition modifying factors range from the societal (e.g. education, occupation, neighbourhood) to the behavioural (smoking, exercise, alcohol, diet).

In most parts of the world older people account for the fastest-growing proportion of the population, with huge corresponding increases in the absolute prevalence of dementia – a trend that is projected to continue well into the future. In addition the World Health Organization has identified depression as the leading cause of disease burden in middle and high income countries. The long-term priorities of this programme are therefore to reduce the risk of these outcomes using a life course approach across all levels of explanation: from societal opportunities and barriers, through behavioural choices, to underlying regulation from genes, endocrine systems, inflammatory mechanisms, and autonomic control.

In regard to the next five years, work within this programme consists of three broad themes:

Capturing mental ageing, involving defining lifetime cognitive trajectories; ascertaining cognitive impairment and dementia; conducting a neuroimaging sub-study; and ascertaining the lifetime prevalence trend of depression and its determinants

Maintaining mental capability in early old age, involving the role of self-organisation and its consequences for self-management of health; and a focus on education and occupational attainment, and retirement, in relation to cognitive skills

Integration of mental and physical ageing, including outcomes in relation to cognitive capability and mental health, cardio-respiratory function, metabolic disorders, musculoskeletal function, and mortality

Publications

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publication icon
Byford M (2014) Adolescent mental health and subsequent parenting: a longitudinal birth cohort study. in Journal of epidemiology and community health

 
Description "British Academy report: "If you could do one thing..." Nine local actions to reduce health inequalities.
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
Impact "British Academy report: "If you could do one thing..." Nine local actions to reduce health inequalities. The report is a collection of opinion pieces on health inequalities from leading social scientists, each of whom has identified one policy intervention that they think local authorities could introduce to improve the health of the local population and reduce health inequalities. The project has been led by a steering group of academic and policy experts and the foreword of the report written by Sir Michael Marmot. The report seeks to help local policymakers improve the health of their communities by presenting evidence from a wide range of social sciences. NSHD paper included in chapter 'THE SCOPE OF ADULT AND FURTHER EDUCATION FOR REDUCING HEALTH INEQUALITIES"
 
Description CLOSER KEW - Particpant engagement
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact MR spoke at a CLOSER KEW on particpant engagement. The talk sparked questions and discussion about best practice in cohort management.
 
Description Consultant to Public Health England: setting priorities for public mental health research
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Membership of a guidance committee
 
Description Consultee: Longitudinal Studies Strategic Review; 2017 Report to the Economic and Social Research Council
Geographic Reach National 
Policy Influence Type Participation in a national consultation
URL https://esrc.ukri.org/files/news-events-and-publications/publications/longitudinal-studies-strategic...
 
Description Round Table meeting at the British Academy - THE VALUE AND FUTURE OF BIRTH COHORT STUDIES FOR SOCIAL SCIENCE AND POLICY.
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Description Stonybrook University Collaboration (SC)
Amount $9,600 (USD)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 12/2014 
End 11/2017
 
Description A life course approach to emerging health disparities in a US birth cohort 
Organisation Columbia University
Department Mailman School of Public Health
Country United States 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution Collectors of the data in a US birth cohort
Impact Data Collected
Start Year 2008
 
Description Chinese University of Hong Kong 
Organisation Chinese University of Hong Kong
Country Hong Kong 
Sector Academic/University 
PI Contribution Provide cognition and mental health expertise. Advising on analysis and manuscript preparation.
Collaborator Contribution Data analysis and manuscript preparation.
Impact PMID: 27807316 Lee AT, Chan WC, Chiu HF, Richards M, Hui LY, Ng SP, Chan WM, Lam LC. Physical health and lifestyle predictors for significant cognitive impairment in community-dwelling Chinese older adults in Hong Kong. Hong Kong Med Journal, 2016, 22 Suppl 6, 37-39. Lee A, Richards M, Chan Wai C, Chiu H, Lee R, Lam L. Lower risk of incident dementia among older adults having 3 servings of vegetables and 2 servings of fruits a day. PMID:28338708 Lee ATC, Richards M, Chan WC, Chiu HFK, Lee RSY, Lam LCW. Association of Daily Intellectual Activities With Lower Risk of Incident Dementia Among Older Chinese Adults. JAMA Psychiatry. 2018;75(7):697-703. doi:10.1001/jamapsychiatry.2018.0657
Start Year 2016
 
Description Collaborating with HALCyon cohorts 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation Medical Research Council (MRC)
Department MRC Human Nutrition Research Unit
Country United Kingdom 
Sector Public 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation University College London
Department Institute of Education (IOE)
Country United Kingdom 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation University of Portsmouth
Country United Kingdom 
Sector Academic/University 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaborating with HALCyon cohorts 
Organisation University of Southampton
Department MRC Lifecourse Epidemiology Unit
Country United Kingdom 
Sector Public 
PI Contribution Providing research expertise
Collaborator Contribution data sharing and research expertise
Impact Numerous research papers including 23818103
Start Year 2008
 
Description Collaboration with Japanese University 
Organisation Tokyo Metropolitan Institute of Medical Science
Department Department of Psychiatry & Behavioral Science
Country Japan 
Sector Academic/University 
PI Contribution NSHD data sharing Housing two researchers at LHA for a period of 12 months. One in 2013-14 and one in 2014-15. Provide advice on the project to do with mental health and aspects of personality To build the collaborative relationship between MRC Unit for Lifelong Health and Aging and the Tokyo Teen Cohort Project.
Collaborator Contribution 1. To seek the key factors which affecting the development of self-regulation in adolescence by using the data from the 1946 British Birth Cohort Study. 2. To investigate a range of health outcomes in relation to discrepancies between verbal and non-verbal cognitive function in NSHD specifically work on social outcomes in those with dyslexia in the NSHD. 3. To learn the management methodology of long-term birth cohort study by committing your current research (MRI study) of the 1946 British Birth Cohort Study. 3. To build the collaborative relationship between MRC Unit for Lifelong Health and Aging and our Tokyo Teen Cohort Project.
Impact A research fellow will be visiting LHA for 12 months to work on NSHD data. Another researcher will be visiting the Unit for 12 months in March 2014. PMID 24714378 Nishida et al PMID 25315221 Nishida et al PMID 26752724 Nishida et al PMID 26449420 Koike et al Adolescent self control behavior predicts body weight through the life course: a prospective birth cohort study. PMID 27279898 Nishida Endo K 2017, Preference for Solitude, Social Isolation, Suicidal Ideation, and Self-Harm in Adolescents.PMID: 28457686 Koike S 2017, Cognitive profiles in childhood and adolescence differ between adult psychotic and affective symptoms: a prospective birth cohort study. Psychol Med. 2017 Oct 9:1-12. PMID:28988550 PMC5729848. Koike S 2018, Catechol O-methyltransferase (COMT) functional haplotype is associated with recurrence of affective symptoms: a prospective birth cohort study. PMID: 29331705 Koike S, Richards M, Wong A, Hardy R. Fat Mass and Obesity Associated (FTO) rs9939609 Polymorphism Modifies the Relationship between body mass index and Affective Symptoms through the Life Course: a prospective birth cohort study. Translational Psychiatry 2018 Mar 13;8(1):62. doi: 10.1038/s41398-018-0110-1. Morimoto Y, Yamasaki S, Ando S, Koike S, Fujikawa S, Kanata S, Endo K, Nakanishi M, Hatch S, Richards M, Kasai K, Hiraiwa-Hasegawa M, Nishida A. Purpose in life and tobacco use among community-dwelling mothers of early adolescents. BMJ Open 2018 Apr 20;8(4):e020586. doi: 10.1136/bmjopen-2017-020586.
Start Year 2012
 
Description Collaboration with Uni of West Sussex/Leiden 
Organisation Leiden University
Country Netherlands 
Sector Academic/University 
PI Contribution We have an ongoing scientific collaboration with key NSHD collaborators in these 2 groups. Scientific lead for study design for a particular project can vary. Involves doctoral or post doctoral supervision, NSHD data sharing, analysis, interpretation, drafting and revising of papers.
Collaborator Contribution We have an ongoing scientific collaboration with key NSHD collaborators in these 2 groups. Scientific lead for study design for a particular project can vary. Involves doctoral or post doctoral supervision, NSHD data sharing, analysis, interpretation, drafting and revising of papers.
Impact Xu PMID: 26125156 Gaysina PMID: 26439078 PhD supervision ET Secinti E 2017. Research Review: Childhood chronic physical illness and adult emotional health - a systematic review and meta-analysis. PMID: 28449285. Xu MK 2017. Monoamine Oxidase A (MAOA) Gene and Personality Traits from Late Adolescence through Early Adulthood: A Latent Variable Investigation. PMID:29075213
Start Year 2014
 
Description Collaboration with Uni of West Sussex/Leiden 
Organisation University of Sussex
Country United Kingdom 
Sector Academic/University 
PI Contribution We have an ongoing scientific collaboration with key NSHD collaborators in these 2 groups. Scientific lead for study design for a particular project can vary. Involves doctoral or post doctoral supervision, NSHD data sharing, analysis, interpretation, drafting and revising of papers.
Collaborator Contribution We have an ongoing scientific collaboration with key NSHD collaborators in these 2 groups. Scientific lead for study design for a particular project can vary. Involves doctoral or post doctoral supervision, NSHD data sharing, analysis, interpretation, drafting and revising of papers.
Impact Xu PMID: 26125156 Gaysina PMID: 26439078 PhD supervision ET Secinti E 2017. Research Review: Childhood chronic physical illness and adult emotional health - a systematic review and meta-analysis. PMID: 28449285. Xu MK 2017. Monoamine Oxidase A (MAOA) Gene and Personality Traits from Late Adolescence through Early Adulthood: A Latent Variable Investigation. PMID:29075213
Start Year 2014
 
Description Collaborations on cognitive ageing NES 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Ongoing collabroation on LHA/NSHD Cognitive ageing programme. Scientific leads on study design and drafting manuscripts vary, involves data sharing, analysis, interpretation and revision of manuscripts.
Collaborator Contribution Experitise in cognitive ageing
Impact Richards et al 2009 (with Batty) Richards et al Lifetime Antecedents of cognitive reserve. In Stern Y (ed). Cognitive Reserve. New York: Psychology Press Hatch et al 2007 17397976 18079429 18718979 Richards, M., Sacker, A., Deary, I.J. (2006) Lifetime antecedents of cognitive reserve. In Stern. Y. (ed.) Cognitive Reserve. Psychology Press, New York. Richards, M. (2006) Do heavier babies make brighter children? In Murray, R., McCabe, J., McGuffin, P., O'Daly, O. and Wright, P. (eds). Beyond nature and nurture: genes, environment and their interplay in psychiatry. Martin Dunitz. Denier N, Clouston SAP, Richards M, Hofer SM. Retirement and cognition: A life course view. Advances in Life Course Research 2017, 31, 11-21. Clouston S, Kotov R, Pietrzak R, Luft B. Gonzalez A, Richards M, Ruggero C, Spiro A, Bromet E. Cognitive impairment among World Trade Center responders: Long-term implications of re-experiencing the 9/11 terrorist attacks. Alzheimer's & Dementia: Diagnosis, Assessment and Disease Monitoring, 2016, 4, 67-75. Kate Xu paper parental bonding instrument PMID 27485970 Received back data set from Kate Xu Secinti E, Thompson EJ, Richards M, Gaysina D. Childhood chronic physical illness and adult emotional health: a systematic review and meta-analysis. In press: Journal of Child Psychology and Psychiatry. 2017 Jul;58(7):753-769. PMID: 28449285. PMID 24598045 Horvat et al PMID 24357571Richards et al PMID 24482683 Silverwood et al PMID 25001968 Gaysina et al PMID 23178897 Gaysina et al Clouston PMID: 27940567 A life course approach to health literacy: The role of gender, educational attainment, and lifetime cognitive capability Denier o Denier N, Clouston SAP, Richards M, Hofer SM. Retirement and cognition: A life course view. Advances in Life Course Research 2017, 31, 11-21. Clouston PMID: 27626057 Cognitive impairment among World Trade Center responders: Long-term implications of re-experiencing the 9/11 terrorist attacks. .Xu MK, Gaysina D, Tsonaka R, Morin AJS, Croudace TJ, Barnett JH, Houwing-Duistermaat J, Richards M, Jones PB; LHA Genetics Group. Monoamine Oxidase A (MAOA) Gene and Personality Traits from Late Adolescence through Early Adulthood: A Latent Variable Investigation. Front Psychol. 2017 Oct 11;8:1736. PMID:29075213
Start Year 2006
 
Description Collaborations on mental health NES 
Organisation King's College London
Department Institute of Psychiatry, Psychology & Neuroscience
Country United Kingdom 
Sector Academic/University 
PI Contribution We have an ongoing scientific collaboration with key NSHD collaborators in these 2 groups. Scientific lead for study design for a particular project can vary. Involves doctoral or post doctoral supervision, NSHD data sharing, analysis, interpretation, drafting and revising of papers.
Collaborator Contribution Development of LHA/NSHD mental health research programme
Impact Publications (not otherwise specified under other collaborations involving these collaborators): Richards M, Goldberg D. Are there early adverse exposures that differentiate depression and anxiety risk? In: Goldberg D, Kendler KS, Sirovatka P, Regier DA (eds). Diagnostic Issues in Depression and Generalized Anxiety Disorder: Refining the Research Agenda for DSM-V. Arlington, VA: American Psychiatric Association 19131382 19379961 18827297 18295901 17976252 17692292 17202554 17487877 16777388 16880486 16734949 16393365 18378866 PMID 25066933 Colman et al PMID 24357583 Byford PMID 26835144 Tikhonoff New award, with Richards as co-investigator: Harmonisation of mental health measures in British birth cohorts. (PI: G Ploubidis, UCL). ESRC. June 2018-July 2019. Total value: £72,918.80
Start Year 2006
 
Description Collaborations on mental health NES 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution We have an ongoing scientific collaboration with key NSHD collaborators in these 2 groups. Scientific lead for study design for a particular project can vary. Involves doctoral or post doctoral supervision, NSHD data sharing, analysis, interpretation, drafting and revising of papers.
Collaborator Contribution Development of LHA/NSHD mental health research programme
Impact Publications (not otherwise specified under other collaborations involving these collaborators): Richards M, Goldberg D. Are there early adverse exposures that differentiate depression and anxiety risk? In: Goldberg D, Kendler KS, Sirovatka P, Regier DA (eds). Diagnostic Issues in Depression and Generalized Anxiety Disorder: Refining the Research Agenda for DSM-V. Arlington, VA: American Psychiatric Association 19131382 19379961 18827297 18295901 17976252 17692292 17202554 17487877 16777388 16880486 16734949 16393365 18378866 PMID 25066933 Colman et al PMID 24357583 Byford PMID 26835144 Tikhonoff New award, with Richards as co-investigator: Harmonisation of mental health measures in British birth cohorts. (PI: G Ploubidis, UCL). ESRC. June 2018-July 2019. Total value: £72,918.80
Start Year 2006
 
Description Computational Platform for Assessment of Cognition In Dementia (C-PLACID) - UCL 
Organisation University College London
Department Institute of Neurology
Country United Kingdom 
Sector Academic/University 
PI Contribution Provide cognitive ageing expertise
Collaborator Contribution The overall objectives of this project are to: - Enhance the cognitive assessment of people with dementia through computational, mathematical and engineering innovation. - Develop a computational platform that will support substantial improvements in the analysis and visualisation of complex cognitive datasets, and the automatization, optimization and innovation of techniques and devices used to acquire cognitive data. The specific objectives are to: - Generate multivariate cognitive profiles in different dementias. - Create algorithms to predict the evolution of cognitive events, particularly in rare and atypical dementias. - Improve existing tests through the automatic measurement of voice reaction times and implementation of psychophysical principles. - Enhance existing cognitive assessment paradigms by utilizing eyetracking. - Develop novel 'instruction-less' tests of cognition suitable for patients with different types and severities of dementia. - Build novel sensors of participant reactions to complex social and other scenarios. - Use virtual reality to evaluate social cognition in fronto-temporal dementia.
Impact EPSRC Sensing and Imaging for the Diagnosis of Dementia grant awarded to Institute of Neurology. The eye-tracking component of this is now embedded within wave 2 of Insight 46
Start Year 2014
 
Description Epigenetics Aberdeen 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration on imprinting methylation; early life influences and later cognition and mood
Collaborator Contribution Collaboration on imprinting methylation; early life influences and later cognition and mood
Impact First Joint meeting 10th March 2016
Start Year 2015
 
Description HAPIEE 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Marcus Richards provided scientific input into the design analysis and publication of a study of congnitive ageing using HAPIEE study.
Collaborator Contribution Informed LHA cognitive programme; raised LHA profile
Impact Birth cohort differentials in congitive functions in Russia and the Czech Republic. Cross sectional results of the HAPIEE study. Horvat et al PMID 24598045 PMID:25503981 Kozela PMID 27154591
Start Year 2006
 
Description KX collaboration 
Organisation Leiden University
Country Netherlands 
Sector Academic/University 
PI Contribution Provides cognitive expertise and NSHD data, advice on study design, data analysis and manuscript preparation
Collaborator Contribution Data analysis and creation of manuscripts
Impact Xu Parental bonding instrument PMID 27485970 Data set received
Start Year 2016
 
Description MODEM study: MOdelling outcome and cost impacts of interventions for DEMentia 
Organisation London School of Economics and Political Science (University of London)
Country United Kingdom 
Sector Academic/University 
PI Contribution Provide cognitive and mental health expertise. Advise on data analysis, manuscript preparation. Attend project meetings
Collaborator Contribution Data analysis and manuscript preparation
Impact Project group meetings. Scientist is a member of the advisory board for this project but not directly involved with the scientific output
Start Year 2016
 
Description SABRE 
Organisation University College London
Department Institute of Cardiovascular Science
Country United Kingdom 
Sector Academic/University 
PI Contribution Provide cognition and mental health expertise. Advising on analysis and manuscript preparation.
Collaborator Contribution Data analysis and manuscript preparation
Impact Park C, Williams E, Chaturvedi N, Tillin T, Stewart R, Richards M, Shibata D, Mayet J, Hughes A. Associations between left ventricular dysfunction and brain structure and function: Findings from the SABRE study. PMID:28420646 PMC5533007
Start Year 2016
 
Description Stonybrook University Collaboration (SC) 
Organisation Stony Brook University
Country United States 
Sector Academic/University 
PI Contribution Collaboration on cognitive ageing in the NSHD Advising and collaborating on papers
Collaborator Contribution Collaboration on cognitive ageing in the NSHD Analysing data, collaborating on papers
Impact PMID: 26315501 Denier N 2017. Retirement and cognition: A life course view. PMID: 28781588. Clouston S 2017.Cognitive impairment among World Trade Center responders: Long-term implications of re-experiencing the 9/11 terrorist attacks. PMID: 27626057 Clouston S 2017. Traumatic exposures, posttraumatic stress disorder, and cognitive functioning in World Trade Center responders. PMID: 29201993
Start Year 2014
 
Description UCL Institute of Ophthalmology 
Organisation University College London
Department Institute of Ophthalmology UCL
Country United Kingdom 
Sector Academic/University 
PI Contribution This is an academic collaboration to assess visual function in NSHD, and produce scientific papers based on that data. Data analysis, mauscipt writing and editing
Collaborator Contribution Data analysis, mauscipt writing and editing
Impact UCL SLMS Capital Equipment Fund (£45,000 towards a digital scanning laser ophthalmoscope) A sub-study will be done for visual assessment in the NSHD neuroimaging substudy: PEEK assessment (acuity, colour and contrast sensitivity) and wide-angled retinal photography. An app has been developed for this assessment and will be launched at the start of December 2014.
Start Year 2012
 
Description UK Dementia Platform 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings Interviews for WP1 Creation of a data portal http://portal.dementiasplatform.uk/account/dataportal data access and deposit documents created First wave of Neuroimaging is completed and the second wave is underway
Start Year 2009
 
Description UK Dementia Platform 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings throughout 2015
Start Year 2014
 
Description UK Dementia Platform 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings Interviews for WP1 Creation of a data portal http://portal.dementiasplatform.uk/account/dataportal data access and deposit documents created First wave of Neuroimaging is completed and the second wave is underway
Start Year 2009
 
Description UK Dementia Platform 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings throughout 2015
Start Year 2014
 
Description UK Dementia Platform 
Organisation Medical Research Council (MRC)
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings throughout 2015
Start Year 2014
 
Description UK Dementia Platform 
Organisation Medical Research Council (MRC)
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings Interviews for WP1 Creation of a data portal http://portal.dementiasplatform.uk/account/dataportal data access and deposit documents created First wave of Neuroimaging is completed and the second wave is underway
Start Year 2009
 
Description UK Dementia Platform 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings throughout 2015
Start Year 2014
 
Description UK Dementia Platform 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings Interviews for WP1 Creation of a data portal http://portal.dementiasplatform.uk/account/dataportal data access and deposit documents created First wave of Neuroimaging is completed and the second wave is underway
Start Year 2009
 
Description UK Dementia Platform 
Organisation Swansea University
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings throughout 2015
Start Year 2014
 
Description UK Dementia Platform 
Organisation Swansea University
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings Interviews for WP1 Creation of a data portal http://portal.dementiasplatform.uk/account/dataportal data access and deposit documents created First wave of Neuroimaging is completed and the second wave is underway
Start Year 2009
 
Description UK Dementia Platform 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings throughout 2015
Start Year 2014
 
Description UK Dementia Platform 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings Interviews for WP1 Creation of a data portal http://portal.dementiasplatform.uk/account/dataportal data access and deposit documents created First wave of Neuroimaging is completed and the second wave is underway
Start Year 2009
 
Description UK Dementia Platform 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings throughout 2015
Start Year 2014
 
Description UK Dementia Platform 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings Interviews for WP1 Creation of a data portal http://portal.dementiasplatform.uk/account/dataportal data access and deposit documents created First wave of Neuroimaging is completed and the second wave is underway
Start Year 2009
 
Description UK Dementia Platform 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings throughout 2015
Start Year 2014
 
Description UK Dementia Platform 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings Interviews for WP1 Creation of a data portal http://portal.dementiasplatform.uk/account/dataportal data access and deposit documents created First wave of Neuroimaging is completed and the second wave is underway
Start Year 2009
 
Description UK Dementia Platform 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings throughout 2015
Start Year 2014
 
Description UK Dementia Platform 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution LHA will provide epidemiological/cognitive ageing expertise to this project and also make available any willing/suitable NSHD participants.
Collaborator Contribution The aim is to create an integrated research environment enabling better, quicker and more cost-effective dementia science; focussing on the molecular determinants of neurodegenration and their translation into therapeutic and public health interventions. The strategic objectives are, in partnership with industry, to deliver: 1. Data integration across cohorts for rapid evidence synthesis. 2. Single-point data access for cohorts studies. 3. Strategic re-purposing of cohorts for discovery and trials readiness. 4. More efficient methods for conducting experimental studies. 5. An experimental programme focussing on the early detection of decline and treatment of dementia. The work programme comprises 15 work packages, each contributing in some way to one or more of the platform's strategic objectives. The platform includes a growing number of networks (currently comprising imaging, informatics and stem cells) which coordinate activity within specialist disciplines and facilitate cross-cutting activity across the platform.
Impact Grant awarded by MRC Regular steering committee meetings Interviews for WP1 Creation of a data portal http://portal.dementiasplatform.uk/account/dataportal data access and deposit documents created First wave of Neuroimaging is completed and the second wave is underway
Start Year 2009
 
Title New data sharing platform - Skylark 
Description Skylark is our new data sharing platform. Skylark is aimed at providing researchers with all the information they need to apply for survey data from the NSHD. Skylark is composed of two companion systems: A wiki (https://skylark.ucl.ac.uk) provides users with a detailed description of the study including all data collections across its 70+ years. The wiki includes: 1. background information about the NSHD; 2. all annotated questionnaires and other paper instruments; 3. a description of the major topics, including information on repeated measures and standard variables; 4. information about the variable search facility and guides on how to locate variables; 5. NSHD information governance; 6. a complete description of the NSHD data sharing process, including all the forms necessary to set up a data sharing agreement and submit a data access request. A variable search facility (https://skylark/ucl.ac.uk/Skylark) provides a platform to locate metadata covering more than 25,000 NSHD variables. Users will need to register, before they can log in to search for variables of interest, which can then be added to personal shopping baskets and saved. Following a successful data sharing application and satisfactory information security assessment, these baskets will then be processed by NSHD staff and the data sent out. This is different from our current data sharing platform, SWIFT, is that it is more secure, transparent and the process of data sharing will be more automated. 
Type Of Technology New/Improved Technique/Technology 
Year Produced 2018 
Impact We are in the testing phase, with a full launch scheduled for end of September / beginning of October. 
URL https://skylark.ucl.ac.uk
 
Description Expert commentary in 'Down with dementia' 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Expert commentary in 'Down with dementia', New Scientist - stimulated thinking



Not aware of any specific impacts
Year(s) Of Engagement Activity 2013
 
Description "Invited member. UK Biobank advisory group for mental health outcomes. " 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact "Invited member. UK Biobank advisory group for mental health outcomes.

"
Year(s) Of Engagement Activity 2015
 
Description 72nd birthday card workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Two workshops were held with ~20 school students (year 9 and year 13) to discuss the history of cohort studies and why they are important. Students were then asked to design a birthday card for our study members using collage. They used old memorabilia from the study. This was a collaboration between a collage artist and two historians from LSHTM. A number of birthday cards were created and two were chosen to send to our study members. As a result of this collaboration a research paper about the history of the NSHD is in progress as well as another public engagement event.
Year(s) Of Engagement Activity 2017
 
Description Brain Awareness Week talk at Braeside School 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Talk at Braeside School, Essex Talk title: Learning about how we learn. As part of Brain Awareness Week, scientists went into schools to talk about our research, but to also to raise awareness of neuromyths. In this interactive talk I discussed ways to study the brain, raised awareness of certain neuromyths and the evidence against them, and discussed tips to improve memory. Filled out relevant work sheets and feedback forms
Most children rated the talk 9/10 and said they enjoyed learning interesting facts about the brain and memory. This talk generated discussion about how to get to become a scientist and what GCSE/A-level/University you need to do. Many students indicated they wanted to learn more about the brain, neuroimaging techniques and mental health.
Year(s) Of Engagement Activity 2010,2017
 
Description British Academy Report 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact British Academy report: "If you could do one thing..." Nine local actions to reduce health inequalities.

The report is a collection of opinion pieces on health inequalities from leading social scientists, each of whom has identified one policy intervention that they think local authorities could introduce to improve the health of the local population and reduce health inequalities. The project has been led by a steering group of academic and policy experts and the foreword of the report written by Sir Michael Marmot. The report seeks to help local policymakers improve the health of their communities by presenting evidence from a wide range of social sciences. NSHD paper included in chapter 'THE SCOPE OF ADULT AND FURTHER EDUCATION FOR REDUCING HEALTH INEQUALITIES'


None to report yet
Year(s) Of Engagement Activity 2014
URL http://www.britac.ac.uk/policy/Health_Inequalities.cfm
 
Description Chair mid-term review group for the Brains for Dementia Research project 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Chair for mid-term review group for the Brains for Dementia Research project
Year(s) Of Engagement Activity 2015
 
Description Comments by LHA Scientist included in New Scientist Article 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Comments in New Scientists were read and were there to stimulate discussion about 'Defusing dementia: Why is risk of Alzheimer's falling?'

None to report
Year(s) Of Engagement Activity 2014
URL http://www.newscientist.com/article/mg22129510.700-defusing-dementia-why-is-risk-of-alzheimers-falli...
 
Description Contribution of a chapter on 'Cognition' to Age UK publication 'Improving later life. Vulnerability and resilience in older people.' 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Contribution of a chapter on 'Cognition' to Age UK publication 'Improving later life. Vulnerability and resilience in older people.'
Year(s) Of Engagement Activity 2015
 
Description Contribution to 'Making the Case for the Social Sciences 11 :Dementia. Published by the Academy of Social Sciences 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Contribution to 'Making the Case for the Social Sciences 11 :Dementia. Published by the Academy of Social Sciences.Launched in the House of Commons on Tuesday 15th March 2016.
Year(s) Of Engagement Activity 2015
 
Description Elevate, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Invited speaker and panelist discussing Brain health in older adults - can cognitive decline be reduced with physical activity? Elevate, London.
Year(s) Of Engagement Activity 2017
 
Description Green Man 2018 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Green Man 2018 - As part of this, with funding from MRC, researchers from UCL partnered with fanSHEN theatre company to create an activity to engage the public with findings from longitudinal life course research.
The successful collaboration led to the development of "Life Course golf course"; part crazy golf, part insight into research from longitudinal cohort studies. In this activity, festival goers were recruited into the life course-themed six-hole golf course. Their caddy (research scientists) navigated them through the 'life course golf course' by discussing and describing how studying birth cohorts have helped us to understand how early life factors can affect later health outcomes.
Over 1,500 adults and children successfully progressed through the course. With an audience made up of families, teenagers and adults who wouldn't normally attend a scientific event, it presented a fantastic opportunity to share about our research in a fun and creative way.
We have had lots of positive feedback and have been approached by other universities and even the Science Museum to explore re-running the activity at future events
Year(s) Of Engagement Activity 2018
URL https://www.ucl.ac.uk/cardiovascular/research/population-science-and-experimental-medicine/mrc-unit-...
 
Description Green Man Festival 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Green Man Festival. Scientists from the Medical Research Council Unit for Lifelong Health and Ageing at UCL wanted to tell people all about their work- a UK birth cohort study of 5000 people who have been studied by the unit ever since they were born in 1946.

Funded by the Wellcome Trust, artists helped to transform the study into 'Tangle', an activity designed to represent how scientists gather up the threads of many people's lives and weave them together to answer research questions. Festival goers were asked to contribute their data on eight variables the scientists examine, for example stress, memory, and health behaviours. Instead of filling out questionnaires, the participants got a piece of coloured fabric for each of their answers, which they wound onto a rope to create their "life course". Anything else that they thought was important in their lives they wrote onto a fabric luggage tag to share with everyone.

More than 600 people came to talk to the scientists and make their own life course, which they then used to help answer a research question: "What is most important to your quality of life." Against the backdrop of Welsh mountains a tapestry frame stood displaying various answers such as, "health", "wealth" and "music" (well, it was a music festival). The new study members threaded their own life course into the section that represented them. It soon became obvious what was most important to their quality of life.
Year(s) Of Engagement Activity 2017
 
Description HALCYon Project Summary Brochure 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact A plain english brochure was created which summarised the main findings from the HALCyon research programme. It has been disseminated to study members, on our website and the New Dynamics of Ageing website and at conferences.

Increased awareness of the findings from the HALCyon programme and the cohorts that were used within this research programme
Year(s) Of Engagement Activity 2014
 
Description HALCYon book launch 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact A book launch was arranged to promote the findings from the HALCyon research programme

Shared knowledge of the HALCyon findings which were published in a book 'A life course approach to healthy ageing'.
Year(s) Of Engagement Activity 2014
 
Description International Innovation Article 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Health professionals
Results and Impact Article was written about the impact of ageing on cognitive function

A life course approach to ageing has been promoted to a potential new audience
Year(s) Of Engagement Activity 2014
 
Description Invited discussant: UCL Festival of Ageing, Margaret Locke Lecture: 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact A Programme leader was a discussant at a lecture by Professor Margaret Lock , Marjorie Bronfman Professor in Social Studies of Medicine, Emerita, Dept. of Social Studies of Medicine, McGill University.

This lecture was convened by Dr Sahra Gibbon to form part of UCL's Festival of Ageing and is supported by UCL Science Medicine and Society Network.



Nothing specific to report for the unit
Year(s) Of Engagement Activity 2013
 
Description Invited member Dementias Platform UK (DPUK) Steering Group. 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited member Dementias Platform UK (DPUK) Steering Group.
Year(s) Of Engagement Activity 2015
 
Description Invited member ILC advisory group: Sustaining Older Society (SOS 2020). 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited member ILC advisory group: Sustaining Older Society (SOS 2020).
Year(s) Of Engagement Activity 2015
 
Description Invited member. Alzheimer's Research UK workshop: 'Research funding into risk reduction and prevention of dementia - barriers and opportunities'. 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited member. Alzheimer's Research UK workshop: 'Research funding into risk reduction and prevention of dementia - barriers and opportunities'.
Year(s) Of Engagement Activity 2015
 
Description Invited member. Consultation: 'Designing devices to track and prevent dementia' (co-sponsored by MRC, WT and industry partners). 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited member. Consultation: 'Designing devices to track and prevent dementia' (co-sponsored by MRC, WT and industry partners).
Year(s) Of Engagement Activity 2015
 
Description Issue Specialist on the Global Council on Brain Health Recommendations on Physical Activity and Brain Health and media pick up 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact MR was an Issue Specialist on the Global Council on Brain Health Recommendations on Physical Activity and Brain Health. The Global Council on Brain Health (GCBH) is an independent collaborative of scientists,health professionals, scholars and policy experts from around the world working in areas of brain health related to human cognition. The GCBH focuses on brain health relating to peoples' ability to think and reason as they age, including aspects of memory, perception and judgment. The GCBH is convened by AARP with support from Age UK to offer the best possible advice about what older adults can do to maintain and improve their brain health. GCBH members come together to discuss specific lifestyle issue areas that may impact peoples' brain health as they age with the goal of providing evidence-based recommendations for people to consider incorporating into their lives. This was picked up by the media and awareness was raised through this channel as well.
Year(s) Of Engagement Activity 2016
 
Description MODEM study - advisory board 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact MR is a member of the MODEM study advisory board. Output from project Kingston A, Robinson L, Booth H, Knapp M, Carol Jagger for the MODEM project (2018) Projections of multi-morbidity in the older population in England to 2035: estimates from the Population Ageing and Care Simulation (PACSim) model, Age and Ageing. Published online 23 January

Dixon J, Knapp M, Karagiannidou M (2018) The effectiveness of advance care planning in improving end of life outcomes for people with dementia and their carers: A systematic review and critical discussion, Journal of Pain and Symptom Management, 55, 1, 132-150

Comas-Herrera A, Knapp M, Wittenberg R, Banerjee S, Bowling A, Grundy E, Jagger C, Farina N, Lombard D, Lorenz K, McDaid D on behalf of the MODEM Project group (2017) MODEM: A comprehensive approach to modelling outcome and costs impacts of interventions for dementia. Protocol paper, BMC Health Services Research, 17, 1, 25

Kingston A, Jagger C (2017) Population Ageing and Care Simulation Model (PACSim). Baseline Dataset and Model Construction (Version 241017), MODEM, London (PDF, 194Kb)

Lorenz K, Freddolino PP, Comas-Herrera A, Knapp M, Damant J (2017) Technology-based tools and services for people with dementia and carers: Mapping technology onto the dementia care pathway, Dementia, published online January 2017
Year(s) Of Engagement Activity 2017
 
Description MODEM study advisory group (MOdelling outcome and cost impacts of interventions for DEMentia; principle partner: Martin Knapp, LSE). 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact MODEM study advisory group (MOdelling outcome and cost impacts of interventions for DEMentia; principle partner: Martin Knapp, LSE).
Year(s) Of Engagement Activity 2015
 
Description MR provided commentary to USA's National Public Radio (NPR) on a new paper based on the CARDIA study 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact MR provided commentary to USA's National Public Radio (NPR) on a new paper based on the CARDIA study, showing that sedentary behaviour (prolonged television watching) and physical inactivity are associated with poorer cognition. This and other commentary was written up as a web-based article in Shots, the online channel for health stories from the NPR Science Desk.
Year(s) Of Engagement Activity 2015
 
Description MRC Festival of Medical Research 2018 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Science Fair in South Cloisters with MRC LMCB and MRC Prion Unit. Our stall used a modified Green Man 2017 "Tangled"
Year(s) Of Engagement Activity 2018
URL http://www.nshd.mrc.ac.uk/news-events/recent-news/mrc-festival-2018-blog/
 
Description MRC Festival of Medical Research Exhibition 70 years of... 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact The activty showcased the history of the cohorts birthday cards as well as old letters from the study and how data used to be presented. The work was presented in a gallery space in collaboration with an art student from the Univerisyt of the arts as well as the president of the UCL medical and arts society. The idea was to create an art exhibition using historical items from the study
Year(s) Of Engagement Activity 2017
 
Description NDA findings brochure 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The New Dynamics of Ageing programme which funded the HALCyon programme created a findings document summerising the results of the HALCyon programme which was distributed to their local networks

Increased awareness of the HALCyon findings and a life course approach to healthy ageing. Increased awareness of longitudinal studies and the cohorts that were involved in HALCyon
Year(s) Of Engagement Activity 2014
 
Description NSHD 70th birthday events and media interest 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact The department organised two birthday events for our study members in London and Manchester. The parties gained significant media attention (print and feature on BBC news). The study member feedback was also very positive and the events were seen as a success.

Health Study - why we owe so much to the class of '46, The Observer
BBC News at 10, Tuesday 1st March
BBC Breakfast short version, Wednesday 2nd March
BBC Inside Science, Thursday 3rd March
The Naked Scientists, Monday 7th March
A video of the London event was created by Dreaming Fish on behalf of the MRC.
The NSHD also featured on a number of local BBC radio stations on Wednesday 1st March.
BBC Radio Cambridgeshire
MRC Network Magazine
MRC Life Magazine
MRC Sound Cloud https://soundcloud.com/the_mrc/mrc-talks-episode-7
Sunday People http://www.mirror.co.uk/news/uk-news/douglas-babies-who-helped-shape-7634768
http://news.xinhuanet.com/english/2016-03/05/c_135159132.htm
Study member interviewed on Radio Stoke 4 March 2016 14:26
Year(s) Of Engagement Activity 2016
 
Description New story on MRC website about Einstein's garden at Green Man Festival 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact News story on the MRC public engagement section of their website detailing the activity we took part in for the Green Man Festival
Year(s) Of Engagement Activity 2017
 
Description Ted Talk by Helen Pearson about The Life Project 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Scientists at the Unit contributed to Helen Pearson's book 'The Life Project'. Helen gave a talk featureing the NSHD for TED. It has had 1,649,889 views and has increased the awareness of the NSHD and longitudinal research.
Year(s) Of Engagement Activity 2017
URL https://www.ted.com/talks/helen_pearson_lessons_from_the_longest_study_on_human_development
 
Description The Wunderkammer improv comedy 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact The Wunderkammer is a very special improvised comedy show. We use short talks from interesting,
passionate people to inspire improvised scenes and stories. Scientist gave a talk on healthy ageing.
Year(s) Of Engagement Activity 2017
 
Description Trustee and board member: Creative Dementia Arts Network (CDAN). 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Trustee and board member: Creative Dementia Arts Network (CDAN).
Year(s) Of Engagement Activity 2015
 
Description UCL Festival of Ageing, Margaret Locke Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact talk sparked questions and discussion afterwards

not sure of any notable impacts yet
Year(s) Of Engagement Activity 2013