Epidemiological and statistical research on health problems of developing countries: MRC Tropical Epidemiology Group
Lead Research Organisation:
London School of Hygiene & Tropical Medicine
Department Name: Epidemiology and Population Health
Abstract
The past decade has seen significant progress in health in developing countries as well as setbacks and new challenges. Gains in health in many low-income countries have been reversed due to the global epidemic of HIV/AIDS and steep increases in tuberculosis (TB). Malaria remains a major killer of children in Africa despite declines in some countries. There is an urgent need to find effective means of controlling these major diseases.
The main aim of the MRC Tropical Epidemiology Group, based at the London School of Hygiene & Tropical Medicine, is to conduct research on interventions against diseases of major public health importance in Africa and other parts of the developing world. We collaborate with scientific groups overseas, including MRC Units in The Gambia and Uganda, assisting with the planning and analysis of research studies. These studies are designed to improve our understanding of risk factors for these diseases, and to evaluate the impact of different control measures. During the next five years, our main focus will continue to be on HIV, TB and malaria, and we will expand our work on non-communicable diseases, which are rapidly increasing in importance in developing countries.
There have been major advances in HIV prevention in recent years, especially around the potential for antiretroviral drugs to be used to prevent HIV transmission. We will work on further studies to evaluate methods of preventing and treating HIV infection, and to scale up interventions, such as voluntary medical male circumcision, that are known to reduce the risk of HIV infection. We will also expand work on integration of care for HIV-patients with treatment of other chronic diseases such as heart disease and diabetes. Research on human papillomavirus (HPV), which can cause cervical cancer, will include studies of how best to deliver HPV vaccination to girls and young women in sub-Saharan Africa.
Our TB research will focus on large-scale trials to assess how best to treat patients co-infected with both TB and HIV, and to improve the ways in which care for TB and HIV are integrated. A new diagnostic test for TB which has the potential to revolutionize TB diagnosis has recently been developed (Xpert MTB/RIF). We will also evaluate the impact and cost-effectiveness of this test for routine TB diagnosis in South Africa.
Substantial reductions in malaria have been reported recently, but much of this progress has been in countries with low levels of malaria, and malaria rates remain unacceptably high in many African countries. In the Sahel region, most of the malaria mortality and morbidity occurs during the short rainy season. We have been closely involved in research showing that giving effective malaria chemoprevention during this period prevents illness and death from malaria in children. We will continue our research in this area, including assessing the impact of this treatment strategy on malaria cases and deaths when delivered through routine health services. We will also continue research on promising malaria vaccines, and to evaluate new methods to control the mosquitoes that transmit malaria.
While the major infectious diseases continue to play a major role, especially in sub-Saharan Africa, there is increasing recognition of the impact of non-communicable diseases. The prevalence of conditions such as cardiovascular disease, diabetes and mental illness is increasing, especially in growing urban centres in developing countries, and will require innovative approaches to prevention and control.
There are few experienced medical statisticians in research institutions and universities in Africa, and an important aspect of our work is to support a fellowship scheme, which provides a two-year training programme for statisticians. In addition, we teach research methods at workshops at collaborating sites and provide informal mentoring and supervision to statisticians and epidemiologists we work with.
The main aim of the MRC Tropical Epidemiology Group, based at the London School of Hygiene & Tropical Medicine, is to conduct research on interventions against diseases of major public health importance in Africa and other parts of the developing world. We collaborate with scientific groups overseas, including MRC Units in The Gambia and Uganda, assisting with the planning and analysis of research studies. These studies are designed to improve our understanding of risk factors for these diseases, and to evaluate the impact of different control measures. During the next five years, our main focus will continue to be on HIV, TB and malaria, and we will expand our work on non-communicable diseases, which are rapidly increasing in importance in developing countries.
There have been major advances in HIV prevention in recent years, especially around the potential for antiretroviral drugs to be used to prevent HIV transmission. We will work on further studies to evaluate methods of preventing and treating HIV infection, and to scale up interventions, such as voluntary medical male circumcision, that are known to reduce the risk of HIV infection. We will also expand work on integration of care for HIV-patients with treatment of other chronic diseases such as heart disease and diabetes. Research on human papillomavirus (HPV), which can cause cervical cancer, will include studies of how best to deliver HPV vaccination to girls and young women in sub-Saharan Africa.
Our TB research will focus on large-scale trials to assess how best to treat patients co-infected with both TB and HIV, and to improve the ways in which care for TB and HIV are integrated. A new diagnostic test for TB which has the potential to revolutionize TB diagnosis has recently been developed (Xpert MTB/RIF). We will also evaluate the impact and cost-effectiveness of this test for routine TB diagnosis in South Africa.
Substantial reductions in malaria have been reported recently, but much of this progress has been in countries with low levels of malaria, and malaria rates remain unacceptably high in many African countries. In the Sahel region, most of the malaria mortality and morbidity occurs during the short rainy season. We have been closely involved in research showing that giving effective malaria chemoprevention during this period prevents illness and death from malaria in children. We will continue our research in this area, including assessing the impact of this treatment strategy on malaria cases and deaths when delivered through routine health services. We will also continue research on promising malaria vaccines, and to evaluate new methods to control the mosquitoes that transmit malaria.
While the major infectious diseases continue to play a major role, especially in sub-Saharan Africa, there is increasing recognition of the impact of non-communicable diseases. The prevalence of conditions such as cardiovascular disease, diabetes and mental illness is increasing, especially in growing urban centres in developing countries, and will require innovative approaches to prevention and control.
There are few experienced medical statisticians in research institutions and universities in Africa, and an important aspect of our work is to support a fellowship scheme, which provides a two-year training programme for statisticians. In addition, we teach research methods at workshops at collaborating sites and provide informal mentoring and supervision to statisticians and epidemiologists we work with.
Technical Summary
We will conduct epidemiological research on HIV, TB, malaria and other diseases of public health importance in developing countries with an emphasis on randomised intervention trials.
In HIV, we will conduct the first trial of the impact of a test-and-treat intervention on HIV incidence in Africa, implementation research on scale-up of male circumcision, and RCTs to reduce early mortality among patients with low CD4 counts and to evaluate different treatment strategies for cryptococcal meningitis.
In TB, we will complete a trial of a four-month pulmonary TB treatment regimen. We will extend our research on treatment strategies for TB and HIV co-infection, including trials to compare 3 treatment strategies in ARV-naïve TB/HIV patients, a CRT to assess the effect of a point-of-care TB test-and-treat algorithm on early mortality in HIV-infected patients accessing ART; and a CRT of the impact of TB diagnosis by Xpert MTB/RIF on mortality and time-to-initiation of treatment.
Malaria research will build on previous work on Seasonal Malaria Chemoprevention (SMC), to evaluate effectiveness of delivery through routine health services, to monitor for adverse effects and to determine the effectiveness of adding SMC to existing control strategies for malaria. We will continue to evaluate multi-component malaria control on Bioko Island, and will develop new collaborations to assess the role of the RTS,S vaccine if licensed.
We will continue trials on lay-health worker interventions to treat common mental disorders, on the beneficial and adverse effects of helminths and antihelmintics on other conditions and of the effectiveness of pneumococcal vaccines. Methodological work will include spatial analysis of spill-over effects in CRTs, and evaluation and prediction of vaccine impact. Finally, we will continue to build research capacity in Africa, including development of the MRC-supported Mwanza Intervention Trials Unit and our programme of TEG training fellowships.
In HIV, we will conduct the first trial of the impact of a test-and-treat intervention on HIV incidence in Africa, implementation research on scale-up of male circumcision, and RCTs to reduce early mortality among patients with low CD4 counts and to evaluate different treatment strategies for cryptococcal meningitis.
In TB, we will complete a trial of a four-month pulmonary TB treatment regimen. We will extend our research on treatment strategies for TB and HIV co-infection, including trials to compare 3 treatment strategies in ARV-naïve TB/HIV patients, a CRT to assess the effect of a point-of-care TB test-and-treat algorithm on early mortality in HIV-infected patients accessing ART; and a CRT of the impact of TB diagnosis by Xpert MTB/RIF on mortality and time-to-initiation of treatment.
Malaria research will build on previous work on Seasonal Malaria Chemoprevention (SMC), to evaluate effectiveness of delivery through routine health services, to monitor for adverse effects and to determine the effectiveness of adding SMC to existing control strategies for malaria. We will continue to evaluate multi-component malaria control on Bioko Island, and will develop new collaborations to assess the role of the RTS,S vaccine if licensed.
We will continue trials on lay-health worker interventions to treat common mental disorders, on the beneficial and adverse effects of helminths and antihelmintics on other conditions and of the effectiveness of pneumococcal vaccines. Methodological work will include spatial analysis of spill-over effects in CRTs, and evaluation and prediction of vaccine impact. Finally, we will continue to build research capacity in Africa, including development of the MRC-supported Mwanza Intervention Trials Unit and our programme of TEG training fellowships.
Planned Impact
As highlighted in the Millennium Development Goals, there is a strong synergy between ill-health and poverty. Our research focuses on diseases that are major causes of morbidity and mortality in resource-poor countries. These diseases have a substantial impact on the socio-economic development of many of these countries. By reducing the rates of important causes of ill health, such measures have the potential to alleviate poverty as well as improving life expectancy. We are expanding our focus on implementation research of proven interventions, and health systems research, which can improve the effectiveness and efficiency of health care delivery and ensure that resources reach the right people.
Many of the diseases we focus on typically affect the poorest in resource-poor countries, and those marginalised from society. We have a strong focus on community-based interventions (for example, in the PopART and TB trials which incorporate home-based HIV and TB testing) which help to overcome barriers to health service access and minimize stigma and discrimination. We also focus on scaling-up interventions which have been proven to be effective - for example male circumcision for HIV prevention, and seasonal malaria chemoprevention in areas with highly seasonal malaria transmission. This implementation research will help ensure access to effective prevention technologies for those who need it, regardless of socio-economic status. Our expanding health systems research (for example on integrating HIV and non-communicable disease treatment and care) will also increase the population-level impact of known effective treatment.
Our research is locally disseminated to study populations, and to regional and national stakeholders and policymakers, as appropriate. This includes providing information to enable policy-makers to make decisions about cost-effective strategies of roll-out (for example, for HPV vaccination or male circumcision scale-up), or access to new technology (such as TB diagnostics including Xpert MTB/RIF). We also play an active role in influencing global health policy and directions for future research, through membership of international technical and policy advisory committees including chairing the WHO Joint Technical Expert Group on Malaria Vaccines in Pivotal Phase 3 Trials & Beyond, the WHO Malaria Policy Advisory Committee Evidence Review Group on Malaria Burden Estimation and the EDCTP Partnership Board; and membership of several other Committees, as outlined in the Case for Support.
Many of the diseases we focus on typically affect the poorest in resource-poor countries, and those marginalised from society. We have a strong focus on community-based interventions (for example, in the PopART and TB trials which incorporate home-based HIV and TB testing) which help to overcome barriers to health service access and minimize stigma and discrimination. We also focus on scaling-up interventions which have been proven to be effective - for example male circumcision for HIV prevention, and seasonal malaria chemoprevention in areas with highly seasonal malaria transmission. This implementation research will help ensure access to effective prevention technologies for those who need it, regardless of socio-economic status. Our expanding health systems research (for example on integrating HIV and non-communicable disease treatment and care) will also increase the population-level impact of known effective treatment.
Our research is locally disseminated to study populations, and to regional and national stakeholders and policymakers, as appropriate. This includes providing information to enable policy-makers to make decisions about cost-effective strategies of roll-out (for example, for HPV vaccination or male circumcision scale-up), or access to new technology (such as TB diagnostics including Xpert MTB/RIF). We also play an active role in influencing global health policy and directions for future research, through membership of international technical and policy advisory committees including chairing the WHO Joint Technical Expert Group on Malaria Vaccines in Pivotal Phase 3 Trials & Beyond, the WHO Malaria Policy Advisory Committee Evidence Review Group on Malaria Burden Estimation and the EDCTP Partnership Board; and membership of several other Committees, as outlined in the Case for Support.
Organisations
- London School of Hygiene & Tropical Medicine (Lead Research Organisation)
- Liverpool School of Tropical Medicine (Collaboration)
- Medical Research Council of South Africa (MRC) (Collaboration)
- Royal Netherlands Chemical Society (Collaboration)
- Ministry of Health and Social Welfare (Collaboration)
- University of KwaZulu-Natal (Collaboration)
- Zimbabwe Population Services International (PSI) (Collaboration)
- Leishmaniasis East Africa Platform (LEAP) (Collaboration)
- National Institute for Medical Research, Tanzania (Collaboration)
- Vanderbilt University (Collaboration)
- Center of Medical Research Lambaréné (Collaboration)
- Johns Hopkins University (Collaboration)
- UNIVERSITY OF BIRMINGHAM (Collaboration)
- THE PIRBRIGHT INSTITUTE (Collaboration)
- MRC/UVRI Uganda Research Unit on AIDS (Collaboration)
- Radboud University Nijmegen (Collaboration)
- Medical Research Council (MRC) (Collaboration)
- University of Zambia (Collaboration)
- Merlin, Afghanistan (Collaboration)
- QUEEN MARGARET UNIVERSITY (Collaboration)
- University of Copenhagen (Collaboration)
- Norwegian University of Life Sciences (NMBU) (Collaboration)
- Catalan Institute of Oncology (ICO) (Collaboration)
- University of Nigeria (Collaboration)
- Centre for Sexual Health and HIV AIDS Research Zimbabwe (CeSHHAR Zimbabwe) (Collaboration)
- UNIVERSITY OF OXFORD (Collaboration)
- National Malaria Control Programme, Cambodia (Collaboration)
- Ignace Deen Hospital (Collaboration)
- Drugs for Neglected Diseases initiative (DNDi) (Collaboration)
- University Cheikh Anta Diop de Dakar (Collaboration)
- National Institutes of Health (NIH) (Collaboration)
- European Commission (Collaboration)
- Sao Paulo State University (Collaboration)
- Médecins Sans Frontières (MSF) (Collaboration)
- Kilimanjaro Christian Medical Centre (KCMS) (Collaboration)
- Umea University (Collaboration)
- Penn State University (Collaboration)
- ST GEORGE'S UNIVERSITY OF LONDON (Collaboration)
- Foundation for Professional Development (Collaboration)
- University of Delhi (Collaboration)
- UNIVERSITY OF EDINBURGH (Collaboration)
- Kenyan Institute for Medical Research (KEMRI) (Collaboration)
- The Statens Serum Institute (SSI) (Collaboration)
- Sangath (Collaboration)
- Kintampo Health Research Centre (Collaboration)
- Zambia AIDS Related Tuberculosis (Collaboration)
- Brown University (Collaboration)
- Navrongo Health Research Centre (NHRC) (Collaboration)
- UNIVERSITY OF LIVERPOOL (Collaboration)
- National Vector-borne Diseases Control Programme (NVDCP) (Collaboration)
- Makerere University (Collaboration)
- IRD Global (Collaboration)
- Institute of Development Research (IRD) (Collaboration)
- Elimination Eight (Collaboration)
- HealthNet (Collaboration)
- University Hospitals in Paris (Collaboration)
- Centers for Disease Control and Prevention (CDC) (Collaboration)
- Institute of Tropical Medicine Antwerp (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- Mbarara National Referral Hospital (Collaboration)
- University of Sussex (Collaboration)
- National Health Laboratory Services, South Africa (Collaboration)
- Family Health International (Collaboration)
- UNIVERSITY OF YORK (Collaboration)
- Armauer Hansen Research Institute (Collaboration)
- Christian Medical College, Vellore (Collaboration)
- Heidelberg University (Collaboration)
- Public Health Foundation of India (Collaboration)
- Karolinska Institute (Collaboration)
- WellcomeTrust Africa Centre (Collaboration)
- Zanzibar Malaria Control Program (Collaboration)
- University of California, San Francisco (Collaboration)
- The Wellcome Trust Sanger Institute (Collaboration)
- University of Bamako (Collaboration)
- In2Care BV (Collaboration)
- Grassroot Soccer (Collaboration)
- Mott Macdonald UK Ltd (Collaboration)
- University of Namibia (Collaboration)
- University of Sheffield (Collaboration)
- ViiV Healthcare (Collaboration)
- Cote D'Ivoire's National Institute of Public Health (Collaboration)
- Khon Kaen University (Collaboration)
- HARVARD UNIVERSITY (Collaboration)
- Fred Hollows Foundation (Collaboration)
- African Population and Health Research Center (Collaboration)
- Wellcome Trust (Collaboration)
- Oswaldo Cruz Foundation (Fiocruz) (Collaboration)
- Health Protection and Research Organisation (HPRO) (Collaboration)
- Innovations for Poverty Action (IPA) (Collaboration)
- University of Zimbabwe (Collaboration)
- Bayer (Collaboration)
- Government of China (Collaboration)
- Biomedical Research and Training Institute (BRTI) (Collaboration)
- Chinese Center for Disease Control and Prevention (China CDC) (Collaboration)
- UNIVERSITY OF GONDAR (Collaboration)
- Aurum Institute (Collaboration)
- Epicentre (Collaboration)
- University of Malawi (Collaboration)
- Monash University (Collaboration)
- University of Yaoundé (Collaboration)
- Sagarmatha Choudhary Eye Hospital (Collaboration)
- University of Ilorin Teaching Hospital, Nigeria (Collaboration)
- ABERYSTWYTH UNIVERSITY (Collaboration)
- Wits Health Consortium (Collaboration)
- CLINTON HEALTH ACCESS INITIATIVE (Collaboration)
- National Malaria Control Programme, Tanzania (Collaboration)
- Makerere University College of Health Sciences (Collaboration)
- National Center for Scientific and Technological Research (CNRST) (Collaboration)
- BOL NIGERIA ! Bclems Outsourcing Limited (Collaboration)
- Entebbe District Hospital (Collaboration)
- Stellenbosch University (Collaboration)
- University of the Witwatersrand (Collaboration)
- Ifakara Health Institute (Collaboration)
- Bill & Melinda Gates Foundation (Collaboration)
- National Hospital of Pneumo-Phtisiology (Collaboration)
- United States President's Emergency Plan for AIDS Relief (Collaboration)
- Entomological Research Centre of Cotonou (CREC) (Collaboration)
- HST (Collaboration)
- University of Cape Town (Collaboration)
- Itad Ltd (Collaboration)
- Georgia Institute of Technology (Collaboration)
- World Health Organization (WHO) (Collaboration)
- University College London (Collaboration)
- University of Tromso (Collaboration)
- Ghana Health Service (Collaboration)
- Avenir Health (Collaboration)
- University of Khartoum (Collaboration)
- Addis Ababa University (Collaboration)
- Nagasaki University (Collaboration)
- Ministry of Health, Uganda (Collaboration)
- Weill Cornell Medical College in Qatar (Collaboration)
- Programme National de Lutte contre la Tuberculose (Collaboration)
- Africa Health Research Institute (Collaboration)
- International Union Against Tuberculosis and Lung Disease (The Union) (Collaboration)
Publications
Cairns ME
(2015)
Seasonality in malaria transmission: implications for case-management with long-acting artemisinin combination therapy in sub-Saharan Africa.
in Malaria journal
Mooney JP
(2018)
Haemolysis and haem oxygenase-1 induction during persistent "asymptomatic" malaria infection in Burkinabé children.
in Malaria journal
Patouillard E
(2013)
Comparative analysis of two methods for measuring sales volumes during malaria medicine outlet surveys.
in Malaria journal
Lo AC
(2013)
Prevalence of molecular markers of drug resistance in an area of seasonal malaria chemoprevention in children in Senegal.
in Malaria journal
Ye Y
(2015)
The Affordable Medicines Facility-malaria (AMFm): are remote areas benefiting from the intervention?
in Malaria journal
Cairns ME
(2014)
Composite endpoints for malaria case-management: not simplifying the picture?
in Malaria journal
Tusting LS
(2015)
The evidence for improving housing to reduce malaria: a systematic review and meta-analysis.
in Malaria journal
Smith JL
(2017)
Malaria risk in young male travellers but local transmission persists: a case-control study in low transmission Namibia.
in Malaria journal
Raghavendra K
(2017)
Monitoring of long-lasting insecticidal nets (LLINs) coverage versus utilization: a community-based survey in malaria endemic villages of Central India.
in Malaria journal
Bradley J
(2017)
Insecticide-treated nets provide protection against malaria to children in an area of insecticide resistance in Southern Benin.
in Malaria journal
Patouillard E
(2015)
Determinants of price setting decisions on anti-malarial drugs at retail shops in Cambodia.
in Malaria journal
Van Den Hoogen LL
(2015)
Serology describes a profile of declining malaria transmission in Farafenni, The Gambia.
in Malaria journal
Bruxvoort K
(2015)
Are Tanzanian patients attending public facilities or private retailers more likely to adhere to artemisinin-based combination therapy?
in Malaria journal
Baschieri A
(2017)
Unintended Childbearing and Child Growth in Northern Malawi.
in Maternal and child health journal
Pathai S
(2013)
Assessment of candidate ocular biomarkers of ageing in a South African adult population: relationship with chronological age and systemic biomarkers.
in Mechanisms of ageing and development
Matowo J
(2015)
Trends in the selection of insecticide resistance in Anopheles gambiae s.l. mosquitoes in northwest Tanzania during a community randomized trial of longlasting insecticidal nets and indoor residual spraying.
in Medical and veterinary entomology
Lule SA
(2019)
A genome-wide association and replication study of blood pressure in Ugandan early adolescents.
in Molecular genetics & genomic medicine
Okell L
(2014)
Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis
in Nature Communications
Walker PG
(2013)
A model of parity-dependent immunity to placental malaria.
in Nature communications
Chotsiri P
(2019)
Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children.
in Nature communications
Stone WJR
(2018)
Publisher Correction: Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity.
in Nature communications
Gonçalves BP
(2017)
Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity.
in Nature communications
Stone WJR
(2018)
Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity.
in Nature communications
Imperial MZ
(2018)
A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis.
in Nature medicine
Imperial MZ
(2019)
Publisher Correction: A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis.
in Nature medicine
Calestani M
(2014)
Patient attitudes towards kidney transplant listing: qualitative findings from the ATTOM study.
in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Kariuki SM
(2015)
Prevalence and factors associated with convulsive status epilepticus in Africans with epilepsy.
in Neurology
Ngugi AK
(2014)
Premature mortality in active convulsive epilepsy in rural Kenya: causes and associated factors.
in Neurology
Ukwaja Kingsley N.
(2014)
A Trial of Mass Isoniazid Preventive Therapy for Tuberculosis Control
in NEW ENGLAND JOURNAL OF MEDICINE
Usuf E
(2016)
Nasopharyngeal colonization of Gambian infants by Staphylococcus aureus and Streptococcus pneumoniae before the introduction of pneumococcal conjugate vaccines.
in New microbes and new infections
Tushabe JV
(2020)
Does Intensive Treatment Select for Praziquantel Resistance in High-Transmission Settings? Parasitological Trends and Treatment Efficacy Within a Cluster-Randomized Trial.
in Open forum infectious diseases
Velen K
(2021)
Performance of GeneXpert MTB/RIF for Diagnosing Tuberculosis Among Symptomatic Household Contacts of Index Patients in South Africa.
in Open forum infectious diseases
Sturt AS
(2021)
Association of Female Genital Schistosomiasis With the Cervicovaginal Microbiota and Sexually Transmitted Infections in Zambian Women.
in Open forum infectious diseases
Sturt AS
(2021)
Female Genital Schistosomiasis and HIV-1 Incidence in Zambian Women: A Retrospective Cohort Study.
in Open forum infectious diseases
Dézoumbé D
(2018)
Prevalence of trachoma in the Republic of Chad: results of 41 population-based surveys.
in Ophthalmic epidemiology
Negash K
(2018)
Prevalence of trachoma in the Afar Region of Ethiopia: results of seven population-based surveys from the Global Trachoma Mapping Project.
in Ophthalmic epidemiology
Alada JJ
(2018)
Prevalence of and risk factors for trachoma in Kwara state, Nigeria: Results of eight population-based surveys from the Global Trachoma Mapping Project.
in Ophthalmic epidemiology
Solomon AW
(2015)
The Global Trachoma Mapping Project: Methodology of a 34-Country Population-Based Study.
in Ophthalmic epidemiology
Duale AB
(2018)
Epidemiology of trachoma and its implications for implementing the "SAFE" strategy in Somali Region, Ethiopia: results of 14 population-based prevalence surveys.
in Ophthalmic epidemiology
| Description | Combining Indoor Residual Spraying and Insecticidal Long Lasting Nets: presentation to WHO Malaria Advisory Committee |
| Geographic Reach | Africa |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | http://www.who.int/malaria/publications/atoz/who-guidance-combining-irs_llins-mar2014.pdf |
| Description | Comment to European Medicine Agency on 'Questions and answers on Data Monitoring Committees issues' (EMA/492010/2018) |
| Geographic Reach | Europe |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | Deployment of pyrethroid-PBO nets |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| Impact | Deployment of pyrethroid-PBO nets in areas where the main malaria vector(s) have pyrethroid resistance |
| URL | http://apps.who.int/iris/bitstream/10665/258939/1/WHO-HTM-GMP-2017.17-eng.pdf?ua=1 |
| Guideline Title | Ebola Virus Disease (EVD) Information for Clinicians in U.S. Healthcare Settings |
| Description | Ebola Clinical Management |
| Geographic Reach | North America |
| Policy Influence Type | Citation in clinical guidelines |
| URL | http://www.cdc.gov/vhf/ebola/healthcare-us/preparing/clinicians.html |
| Description | HIV self-testing WHO prequalification |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Note that Oraquick was PQed in 2017 and INSTI in 2018 - one of the goals of the STAR project was to develop a market for HIV Self Testing approved by regulatory bodies. https://globenewswire.com/news-release/2018/11/28/1658183/0/en/INSTI-HIV-Self-Test-Earns-WHO-Prequalification-Status-for-Home-Testing.html and http://phx.corporate-ir.net/phoenix.zhtml?c=99740&p=irol-newsArticle_print&ID=2287929) |
| URL | https://globenewswire.com/news-release/2018/11/28/1658183/0/en/INSTI-HIV-Self-Test-Earns-WHO-Prequal... |
| Description | HIV services in Zambia and S Africa |
| Geographic Reach | Africa |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Influenced training of practitioners or researchers delivering HIV services in Zambia and S Africa. |
| Description | Membership of WHO Vector Control Advisory Group |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| URL | http://www.who.int/neglected_diseases/vector_ecology/VCAG/en |
| Description | REMSTART trial |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| URL | http://www.who.int/hiv/pub/guidelines/advanced-HIV-disease/en/ |
| Description | The Friendship Bench |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | A recently carried out randomized control trial showed that the Friendship Bench can deliver a successful, culturally acceptable and reliable treatment program for depression on a primary care level (Chibanda, D, Bowers, T, Verhey, R, Rusakaniko, S, Abas, M, Weiss, H A, Araya, R. The Friendship Bench programme: a cluster randomised controlled trial of a brief psychological intervention for common mental disorders delivered by lay health workers in Zimbabwe. International journal of mental health systems 2015a; 9, 21). It also addresses the stigma of mental illness in society, and the training of lay workers to deliver problem solving therapy helps address the deficit of mental health specialists in Zimbabwe. |
| URL | http://www.friendshipbenchzimbabwe.org |
| Description | WHO Vector Control Advisory Group |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| URL | http://www.who.int/neglected_diseases/vector_ecology/VCAG/en/ |
| Description | A comparative trial of seasonal vaccination with the malaria vaccine RTS,S/AS01, seasonal malaria chemoprevention and the two interventions combined |
| Amount | £3,491,906 (GBP) |
| Funding ID | MR/P006876/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 06/2020 |
| Description | ACCESS-SMC activities |
| Amount | £308,900 (GBP) |
| Organisation | Malaria Consortium Africa, Kampala |
| Sector | Charity/Non Profit |
| Country | Uganda |
| Start | 11/2017 |
| End | 02/2019 |
| Description | Adolescent 360 Evaluation |
| Amount | $479,341 (USD) |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 03/2016 |
| End | 08/2021 |
| Description | Advances in approaches to optimise testing for sexually transmitted infections |
| Amount | £36,552 (GBP) |
| Organisation | Public Health England |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2018 |
| End | 07/2019 |
| Description | Africa Centre Collaborations Fund |
| Amount | £9,000 (GBP) |
| Funding ID | ISSF/ADDE814710 |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2014 |
| End | 06/2015 |
| Description | AmBisone |
| Amount | £10,677 (GBP) |
| Organisation | Médecins Sans Frontières (MSF) |
| Sector | Charity/Non Profit |
| Country | France |
| Start | 08/2016 |
| End | 03/2018 |
| Description | Aurum Institute - Highly TB exposed, persistently uninfected South African gold miners: HETU study |
| Amount | $971,347 (USD) |
| Organisation | Aurum Institute |
| Sector | Charity/Non Profit |
| Country | South Africa |
| Start | 11/2014 |
| End | 12/2016 |
| Description | BMFG - China Gates |
| Amount | $418,871 (USD) |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2014 |
| End | 09/2019 |
| Description | BMGF - Penn State Uni (Eave Tubes Trial) |
| Amount | $938,000 (USD) |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2015 |
| End | 11/2018 |
| Description | CDC/Fiotec Zika project |
| Amount | $184,000 (USD) |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Sector | Public |
| Country | United States |
| Start | 04/2017 |
| End | 08/2018 |
| Description | CHIDO Trial |
| Amount | $54,941 (USD) |
| Organisation | Centre for Sexual Health and HIV AIDS Research Zimbabwe (CeSHHAR Zimbabwe) |
| Sector | Charity/Non Profit |
| Country | Zimbabwe |
| Start | 01/2016 |
| End | 12/2017 |
| Description | Challenge TB (WHIP3TB Aurum) |
| Amount | $14,264,118 (USD) |
| Funding ID | AID-OAA-A-14-00029 |
| Organisation | United States Agency for International Development |
| Sector | Public |
| Country | United States |
| Start | 03/2016 |
| End | 09/2019 |
| Description | Cluster randomized trial of the Zvandiri programme |
| Amount | £36,578 (GBP) |
| Organisation | Viiv Healthcare |
| Sector | Private |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 12/2018 |
| Description | Combined HIV African Prevention Study: On demand Truvada and F/TAF Pre-exposure and Post exposure prophylaxis to protect adolescents from HIV |
| Amount | € 2,999,999 (EUR) |
| Funding ID | RIA2016MC-1616 |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 03/2018 |
| End | 03/2021 |
| Description | DIAMA |
| Amount | € 2,967,202 (EUR) |
| Funding ID | DRIA2014-326 |
| Organisation | Sixth Framework Programme (FP6) |
| Department | European and Developing Countries Clinical Trials Partnership |
| Sector | Public |
| Country | Netherlands |
| Start | 05/2016 |
| End | 05/2021 |
| Description | DNDI Technical agreement (AfriCoLeish II) |
| Amount | £37,000 (GBP) |
| Organisation | Drugs for Neglected Diseases initiative (DNDi) |
| Sector | Charity/Non Profit |
| Country | Switzerland |
| Start | 03/2017 |
| End | 03/2018 |
| Description | Data Collection & Analysis of the Zimbabwe & the Friendship Bench: Deployment of Services for Formative Efforts to Understand Mental Health Issues among HIV-infected Adolescents Project Research Findings |
| Amount | $14,000 (USD) |
| Organisation | United States President's Emergency Plan for AIDS Relief |
| Sector | Public |
| Country | United States |
| Start | 03/2017 |
| End | 09/2018 |
| Description | EU FP7 Theme: AfriCoLeish |
| Amount | € 3,000,000 (EUR) |
| Funding ID | 305178 |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 01/2013 |
| End | 12/2016 |
| Description | Effects of metronidazole plus intermittent preventive treatment of malaria in pregnancy on birth outcomes: a randomised controlled trial in Zambia. |
| Amount | £2,496,504 (GBP) |
| Funding ID | MR/S004998/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 10/2022 |
| Description | Electronic Data Capture to support rapid epidemiological research and vaccine trials during: Stage 2 |
| Amount | £539,143 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2020 |
| Description | Epidemiological and statistical research on health problems of low and middle-income countries: MRC Tropical Epidemiology Group (TEG) |
| Amount | £4,128,086 (GBP) |
| Funding ID | MR/R010161/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 10/2024 |
| Description | GSK Fellowships |
| Amount | £184,050 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 03/2018 |
| End | 08/2022 |
| Description | INTREPID II |
| Amount | £279,812 (GBP) |
| Funding ID | MR/P025927/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 09/2022 |
| Description | Investigation of HEV transmission dynamics and epidemic evolution to improve outbreak control efforts among emergency affected populations |
| Amount | $11,687 (USD) |
| Organisation | CDC Foundation |
| Sector | Public |
| Country | United States |
| Start | 12/2015 |
| End | 12/2016 |
| Description | Joint Global Health Trials |
| Amount | £2,986,615 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 02/2021 |
| Description | Joint Global Health Trials (MENISCUS-2) |
| Amount | £203,351 (GBP) |
| Funding ID | MR/P020283/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 12/2018 |
| Description | Joint Global Health Trials 2013 |
| Amount | £836,321 (GBP) |
| Funding ID | MR/L00433X/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 12/2013 |
| End | 05/2016 |
| Description | Joint Global Health Trials 2013 |
| Amount | £1,856,394 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2014 |
| End | 09/2017 |
| Description | Joint Global Health Trials Development Grant |
| Amount | £200,000 (GBP) |
| Funding ID | MR/P020283/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 10/2018 |
| Description | MRC Adolescent Health Call (Friendship Bench) |
| Amount | £560,269 (GBP) |
| Funding ID | MR/P012485/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 12/2018 |
| Description | MSF - TB PRACTECAL |
| Amount | £542,440 (GBP) |
| Organisation | Médecins Sans Frontières (MSF) |
| Sector | Charity/Non Profit |
| Country | France |
| Start | 09/2013 |
| End | 12/2022 |
| Description | MSF SAM Trial |
| Amount | £32,600 (GBP) |
| Organisation | Médecins Sans Frontières (MSF) |
| Sector | Charity/Non Profit |
| Country | France |
| Start | 12/2017 |
| End | 12/2019 |
| Description | Mass drug administration of ivermectin and dihydroartemisinin-piperaquine as an additional intervention for malaria elimination |
| Amount | £2,057,637 (GBP) |
| Funding ID | MC_EX_MR/R006075/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2017 |
| End | 01/2021 |
| Description | Master's Fellowship in Epidemiology and Medical Statistics |
| Amount | £116,925 (GBP) |
| Organisation | Sixth Framework Programme (FP6) |
| Department | European and Developing Countries Clinical Trials Partnership |
| Sector | Public |
| Country | Netherlands |
| Start | 08/2014 |
| End | 09/2016 |
| Description | Master's Fellowship in Epidemiology and Medical Statistics |
| Amount | £119,985 (GBP) |
| Organisation | Sixth Framework Programme (FP6) |
| Department | European and Developing Countries Clinical Trials Partnership |
| Sector | Public |
| Country | Netherlands |
| Start | 09/2014 |
| End | 09/2016 |
| Description | Master's Fellowship in Epidemiology and Medical Statistics |
| Amount | £119,985 (GBP) |
| Organisation | Sixth Framework Programme (FP6) |
| Department | European and Developing Countries Clinical Trials Partnership |
| Sector | Public |
| Country | Netherlands |
| Start | 08/2014 |
| End | 09/2016 |
| Description | New Investigator Research Grant - Suzanna Francis |
| Amount | £917,566 (GBP) |
| Funding ID | MR/N023692/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2016 |
| End | 06/2019 |
| Description | Newton Household Screening for TB |
| Amount | £57,297 (GBP) |
| Organisation | Medical Research Council of South Africa (MRC) |
| Sector | Public |
| Country | South Africa |
| Start | 04/2016 |
| End | 12/2018 |
| Description | PRIDE (PRemIum for aDolEscents). |
| Amount | £3,715,770 (GBP) |
| Funding ID | 106919/A/15/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 10/2022 |
| Description | Public Health Intervention Development Scheme |
| Amount | £143,663 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2014 |
| End | 10/2014 |
| Description | Public Health Intervention Development Scheme |
| Amount | £150,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2014 |
| End | 07/2015 |
| Description | RAFAScreen |
| Amount | € 39,856 (EUR) |
| Organisation | National Tuberculosis Programme of Benin |
| Sector | Public |
| Country | Benin |
| Start | 07/2015 |
| End | 07/2016 |
| Description | RIFASHORT (Joint funded initiatives) |
| Amount | £2,595,670 (GBP) |
| Funding ID | MR/M006127/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 12/2019 |
| Description | Research & Innovation Action |
| Amount | € 41,385 (EUR) |
| Funding ID | 666094 |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 11/2014 |
| End | 10/2015 |
| Description | Strengthening Capacity to improve Adolescent Health & Wellbeing in Southern Africa |
| Amount | £134,688 (GBP) |
| Organisation | Viiv Healthcare |
| Sector | Private |
| Country | United Kingdom |
| Start | 07/2018 |
| End | 07/2020 |
| Description | Strengthening East and Southern African capacity for menstrual hygiene management (MHM) research |
| Amount | £24,767 (GBP) |
| Organisation | Academy of Medical Sciences (AMS) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2018 |
| End | 08/2019 |
| Description | TE NTD Research for Sightsavers |
| Amount | £91,236 (GBP) |
| Organisation | Sightsavers |
| Sector | Charity/Non Profit |
| Country | Global |
| Start | 12/2014 |
| End | 12/2015 |
| Description | Technical Support for Insecticide Resistance in India |
| Amount | $63,887 (USD) |
| Funding ID | 39312 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 12/2015 |
| End | 12/2016 |
| Description | Tuberculosis: Innovative Delivery Approaches |
| Amount | $203,358 (USD) |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2014 |
| End | 10/2016 |
| Description | UNITAID Strategic Objective 4: Treatment of Malaria (Round 2) |
| Amount | $67,400,000 (USD) |
| Organisation | World Health Organization (WHO) |
| Department | UNITAID |
| Sector | Public |
| Country | Switzerland |
| Start | 01/2015 |
| End | 12/2018 |
| Description | UNITAID Strategic Objective 6: Preventatives for HIV/Aids, TB and Malaria |
| Amount | $7,480,000 (USD) |
| Organisation | World Health Organization (WHO) |
| Department | UNITAID |
| Sector | Public |
| Country | Switzerland |
| Start | 01/2015 |
| End | 12/2018 |
| Description | UNITAID/PSI STAR Project |
| Amount | $244,169 (USD) |
| Organisation | World Health Organization (WHO) |
| Department | UNITAID |
| Sector | Public |
| Country | Switzerland |
| Start | 09/2015 |
| End | 10/2017 |
| Description | WT Senior Research Fellowship for Eugene Kinyanda |
| Amount | £2,021,099 (GBP) |
| Funding ID | 205069/Z/16/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2017 |
| End | 03/2022 |
| Description | What is the sensitivity, specificity, and unintended consequences of a trial of (nonTB) antibiotics |
| Amount | £68,580 (GBP) |
| Organisation | University of Malawi |
| Sector | Academic/University |
| Country | Malawi |
| Start | 08/2017 |
| End | 08/2020 |
| Description | YATHU YATHU ("For us by us"): A Cluster Randomised Trial of community-based SRH and HIV services for adolescents and young people in Zambia |
| Amount | £2,183,245 (GBP) |
| Funding ID | MR/R022216/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2018 |
| End | 06/2022 |
| Description | Zero TB Baseline & Endline Survey (IRD Pakistan) |
| Amount | $76,124 (USD) |
| Organisation | Global Fund to Fight AIDS, Tuberculosis and Malaria |
| Sector | Charity/Non Profit |
| Country | Switzerland |
| Start | 03/2017 |
| End | 12/2017 |
| Description | Zvandiri Project |
| Amount | £43,147 (GBP) |
| Organisation | Viiv Healthcare |
| Sector | Private |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 12/2016 |
| Title | Statistical methods for stepped wedge trials |
| Description | Developing appropriate methods of analysis for use in stepped wedge trials |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Adoption of new more appropriate statistical methods that reflect the true uncertainty of trial results |
| Title | ART and HPV |
| Description | Data from a systematic review on ART and HPV infection |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | None yet |
| URL | http://datacompass.lshtm.ac.uk |
| Title | Data for Thinking Healthy Programme India trial (THPP-India) |
| Description | An anonymised dataset of 280 women (one row per woman) who gave informed consent to participate in an individually-randomised, parallel, superiority, controlled trial in Goa, India in 2014-2016. The intervention was an adapted version of the Thinking Healthy Programme, delivered by peers; the control was enhanced usual care. Further details are available in the published protocol and paper. The dataset contains records of variables on stratified randomisation, socio-demographic information, depression and related outcomes, and therapy adherence. Visits occurred at baseline, and 3 and 6 months post-natal. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | none yet |
| URL | http://datacompass.lshtm.ac.uk/id/eprint/793 |
| Title | Data for Thinking Healthy Programme Pakistan trial (THPP-Pakistan) |
| Description | An anonymised dataset of 570 women (one row per woman) who gave informed consent to participate in a cluster randomised, parallel, superiority, controlled trial in Rawalpindi, Pakistan in 2014-2017. The intervention was an adapted version of the Thinking Healthy Programme, delivered by peers; the control was enhanced usual care. Further details are available in the published protocol and paper. The dataset contains records of variables on stratified randomisation and clusters, socio-demographic information, depression and related outcomes, and therapy adherence. Visits occurred at baseline, and 3 and 6 months post-natal. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | None yet |
| URL | http://datacompass.lshtm.ac.uk/id/eprint/794 |
| Title | HC-HIV IPD dataset |
| Description | The HC-HIV IPD database 18 HIV prevention studies, including 37,124 women (43,613 woman-years) and 1,830 incident HIV infections |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | Impact on WHO policy for contraception |
| Title | PREMIUM twelve-month follow-up trial: Clinical Outcomes and Cost-effectiveness dataset from the Counselling for Alcohol Problems (CAP) RCT |
| Description | Datasets for the two PREMIUM trials |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | None yet |
| URL | http://datacompass.lshtm.ac.uk/514/ |
| Title | PREMIUM twelve-month follow-up trial: Clinical Outcomes and Cost-effectiveness dataset from the Healthy Activity Program (HAP) RCT |
| Description | Datasets for the two PREMIUM trials |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | None yet |
| URL | http://datacompass.lshtm.ac.uk/513/ |
| Title | STIMA Dataset |
| Description | Revised database from HC-HIV database that included 18 HIV prevention studies (cohort studies and randomized controlled trials; conducted during 1993±2011), representing >37,000 women, that tested participants for >1 selected STIs or BV at baseline |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | None yet |
| Title | VMB Dataset |
| Description | Combined data from 16SrRNA sequencing, NMR metabolomic and 33 immune protein targets from 221 women |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | No |
| Impact | None yet |
| Description | 3HPstudy |
| Organisation | Aurum Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Study design and analysis |
| Collaborator Contribution | Study design, co-ordination, economic modelling, trial recruitment |
| Impact | Multi-disciplinary: public health, health economics, statistics, trial design |
| Start Year | 2015 |
| Description | 3HPstudy |
| Organisation | Johns Hopkins University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Study design and analysis |
| Collaborator Contribution | Study design, co-ordination, economic modelling, trial recruitment |
| Impact | Multi-disciplinary: public health, health economics, statistics, trial design |
| Start Year | 2015 |
| Description | ALERRT |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | study design & analysis |
| Collaborator Contribution | study design & analysis, collaborator meetings |
| Impact | Multi-disciplinary: epidemiology, public health, statistics, clinical trials |
| Start Year | 2018 |
| Description | AMARI |
| Organisation | Addis Ababa University |
| Country | Ethiopia |
| Sector | Academic/University |
| PI Contribution | Steering committee member |
| Collaborator Contribution | Study co-ordination |
| Impact | PhD and post-doctoral researchers enrolled |
| Start Year | 2015 |
| Description | AMARI |
| Organisation | University of Cape Town |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Steering committee member |
| Collaborator Contribution | Study co-ordination |
| Impact | PhD and post-doctoral researchers enrolled |
| Start Year | 2015 |
| Description | AMARI |
| Organisation | University of Malawi |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | Steering committee member |
| Collaborator Contribution | Study co-ordination |
| Impact | PhD and post-doctoral researchers enrolled |
| Start Year | 2015 |
| Description | AMARI |
| Organisation | University of Zimbabwe |
| Country | Zimbabwe |
| Sector | Academic/University |
| PI Contribution | Steering committee member |
| Collaborator Contribution | Study co-ordination |
| Impact | PhD and post-doctoral researchers enrolled |
| Start Year | 2015 |
| Description | AZ-SMC trial |
| Organisation | National Center for Scientific and Technological Research (CNRST) |
| Department | Institute of Research in Health Sciences |
| Country | Burkina Faso |
| Sector | Public |
| PI Contribution | Study design, analysis |
| Collaborator Contribution | Clinical, field, lab studies |
| Impact | NEJM paper (DOI: 10.1056/NEJMoa1811400) Multidisciplinary: epidemiology, statistics, clinical trials Informed WHO guidelines on AZ deployment (still in development) |
| Start Year | 2014 |
| Description | AZ-SMC trial |
| Organisation | University of Bamako |
| Department | Malaria Research and Training Centre (MRTC) Bamako |
| Country | Mali |
| Sector | Academic/University |
| PI Contribution | Study design, analysis |
| Collaborator Contribution | Clinical, field, lab studies |
| Impact | NEJM paper (DOI: 10.1056/NEJMoa1811400) Multidisciplinary: epidemiology, statistics, clinical trials Informed WHO guidelines on AZ deployment (still in development) |
| Start Year | 2014 |
| Description | Adolescents 360 |
| Organisation | Avenir Health |
| Country | United States |
| Sector | Private |
| PI Contribution | Principle investigator at LSHTM, study design, analysis |
| Collaborator Contribution | Project management, process evaluation, cost analysis, liaison with implementers |
| Impact | One paper submitted, two are in preparation. Disciplines include qualitative research, health economics, epidemiology |
| Start Year | 2016 |
| Description | Adolescents 360 |
| Organisation | Avenir Health |
| Country | United States |
| Sector | Private |
| PI Contribution | Principle investigator at LSHTM, study design, analysis |
| Collaborator Contribution | Project management, process evaluation, cost analysis, liaison with implementers |
| Impact | Multi-disciplinary: qualitative research, health economics, epidemiology. Four papers published, two papers in preparation, 3 conference presentations. |
| Start Year | 2016 |
| Description | Adolescents 360 |
| Organisation | BOL NIGERIA ! Bclems Outsourcing Limited |
| Sector | Private |
| PI Contribution | Principle investigator at LSHTM, study design, analysis |
| Collaborator Contribution | Project management, process evaluation, cost analysis, liaison with implementers |
| Impact | Multi-disciplinary: qualitative research, health economics, epidemiology. Four papers published, two papers in preparation, 3 conference presentations. |
| Start Year | 2016 |
| Description | Adolescents 360 |
| Organisation | Itad Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Principle investigator at LSHTM, study design, analysis |
| Collaborator Contribution | Project management, process evaluation, cost analysis, liaison with implementers |
| Impact | One paper submitted, two are in preparation. Disciplines include qualitative research, health economics, epidemiology |
| Start Year | 2016 |
| Description | Adolescents 360 |
| Organisation | Itad Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Principle investigator at LSHTM, study design, analysis |
| Collaborator Contribution | Project management, process evaluation, cost analysis, liaison with implementers |
| Impact | Multi-disciplinary: qualitative research, health economics, epidemiology. Four papers published, two papers in preparation, 3 conference presentations. |
| Start Year | 2016 |
| Description | Adolescents 360 |
| Organisation | National Institute for Medical Research, Tanzania |
| Department | Mwanza Intervention Trials Unit (MITU) |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | Principle investigator at LSHTM, study design, analysis |
| Collaborator Contribution | Project management, process evaluation, cost analysis, liaison with implementers |
| Impact | Multi-disciplinary: qualitative research, health economics, epidemiology. Four papers published, two papers in preparation, 3 conference presentations. |
| Start Year | 2016 |
| Description | Adolescents 360 |
| Organisation | National Institute for Medical Research, Tanzania |
| Department | Mwanza Intervention Trials Unit (MITU) |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | Principle investigator at LSHTM, study design, analysis |
| Collaborator Contribution | Project management, process evaluation, cost analysis, liaison with implementers |
| Impact | One paper submitted, two are in preparation. Disciplines include qualitative research, health economics, epidemiology |
| Start Year | 2016 |
| Description | AfricoLeisch Consortium |
| Organisation | Drugs for Neglected Diseases initiative (DNDi) |
| Country | Switzerland |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical lead and data management oversight |
| Collaborator Contribution | Intellectual input and expertise; access to data; capacity building; research dissemination |
| Impact | Treatment trials in progress |
| Start Year | 2013 |
| Description | AfricoLeisch Consortium |
| Organisation | European Commission |
| Country | European Union (EU) |
| Sector | Public |
| PI Contribution | Statistical lead and data management oversight |
| Collaborator Contribution | Intellectual input and expertise; access to data; capacity building; research dissemination |
| Impact | Treatment trials in progress |
| Start Year | 2013 |
| Description | AfricoLeisch Consortium |
| Organisation | Institute of Tropical Medicine Antwerp |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | Statistical lead and data management oversight |
| Collaborator Contribution | Intellectual input and expertise; access to data; capacity building; research dissemination |
| Impact | Treatment trials in progress |
| Start Year | 2013 |
| Description | AfricoLeisch Consortium |
| Organisation | Médecins Sans Frontières (MSF) |
| Country | France |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical lead and data management oversight |
| Collaborator Contribution | Intellectual input and expertise; access to data; capacity building; research dissemination |
| Impact | Treatment trials in progress |
| Start Year | 2013 |
| Description | AfricoLeisch Consortium |
| Organisation | University of Gondar |
| Country | Ethiopia |
| Sector | Academic/University |
| PI Contribution | Statistical lead and data management oversight |
| Collaborator Contribution | Intellectual input and expertise; access to data; capacity building; research dissemination |
| Impact | Treatment trials in progress |
| Start Year | 2013 |
| Description | AfricoLeisch Consortium |
| Organisation | University of Khartoum |
| Country | Sudan |
| Sector | Academic/University |
| PI Contribution | Statistical lead and data management oversight |
| Collaborator Contribution | Intellectual input and expertise; access to data; capacity building; research dissemination |
| Impact | Treatment trials in progress |
| Start Year | 2013 |
| Description | Assessing the impact of the introduction of pneumococcal conjugate vaccine into the childhood vaccine programme |
| Organisation | Wellcome Trust |
| Department | KEMRI-Wellcome Trust Research Programme |
| Country | Kenya |
| Sector | Academic/University |
| PI Contribution | Providing statistical support |
| Collaborator Contribution | Principal investiagors and data collection |
| Impact | Paper on efficacy of different pneumococcal conjugate vaccine schedules against pneumonia, hospitalisation, and mortality in the Gambia published in Vaccine (2014) |
| Start Year | 2014 |
| Description | Associations between latent TB infection in mothers and infant immune response to immunisations |
| Organisation | University of Malawi |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | Statistical contribution to trial design. We will be supervising data analysis going forward. |
| Collaborator Contribution | Significant intellectual input and mutual exchange of ideas |
| Impact | None yet. |
| Start Year | 2014 |
| Description | B-GAP |
| Organisation | Biomedical Research and Training Institute (BRTI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Study design and analysis |
| Collaborator Contribution | study design; coordination; field work; economic modelling; |
| Impact | None yet. |
| Start Year | 2017 |
| Description | CADDE (UK-Brazil) |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Study design and analysis |
| Collaborator Contribution | As previous, plus field and lab work. |
| Impact | Multi-disciplinary: epidemiology, ecology, entomology, virology, GIS, statistics, public health. |
| Start Year | 2018 |
| Description | CHIDO trial |
| Organisation | Centre for Sexual Health and HIV AIDS Research Zimbabwe (CeSHHAR Zimbabwe) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2015 |
| Description | CHIEDZA |
| Organisation | Biomedical Research and Training Institute (BRTI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Study design and analysis |
| Collaborator Contribution | study design; coordination; field work; economic modelling; |
| Impact | No outputs as yet. Collaboration is multi disciplinary including clinical trials, epidemiology, public health, statistics. |
| Start Year | 2016 |
| Description | CMV immunology |
| Organisation | University of Oxford |
| Department | Nuffield Department of Experimental Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | statistical analysis |
| Collaborator Contribution | data collection, lab analysis |
| Impact | paper in Clinical Infectious Diseases, 2 others being written, Multi-disciplinary: immunogenetics, epidemiology |
| Start Year | 2017 |
| Description | COSTOP trial |
| Organisation | MRC/UVRI Uganda Research Unit on AIDS |
| Country | Uganda |
| Sector | Public |
| PI Contribution | Design, implementation, analysis, interpret |
| Collaborator Contribution | Design, implementation, analysis, interpret |
| Impact | Seven papers; 1 oral presentation at CROI 2015 Multidisciplinary: Clinical medicine, epidemiology, qualitative research |
| Start Year | 2010 |
| Description | CRT - creation strategies to increase voluntary medical male circumcision uptake in Zimbabwe |
| Organisation | Centre for Sexual Health and HIV AIDS Research Zimbabwe (CeSHHAR Zimbabwe) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical support |
| Collaborator Contribution | Study coordination |
| Impact | Multi-disciplinary: Epidemiology, economics, qualitative |
| Start Year | 2018 |
| Description | CRT - creation strategies to increase voluntary medical male circumcision uptake in Zimbabwe |
| Organisation | Zimbabwe Population Services International (PSI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical support |
| Collaborator Contribution | Study coordination |
| Impact | Multi-disciplinary: Epidemiology, economics, qualitative |
| Start Year | 2018 |
| Description | CRT of an intensified TB/HIV prevention intervention in Malawi |
| Organisation | Wellcome Trust |
| Department | Malawi-Liverpool Wellcome Trust Clinical Research Programme |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Trial leadership and all other aspects |
| Impact | Intervention evaluation period is complete and final survey (HIV prevalence) is underway. Trial analysis is ongoing. Paper on a sub-trial of home-based versus community-based initiation of HIV care published in JAMA (2014). |
| Start Year | 2010 |
| Description | CRT of intensive versus standard anthelminthic treatment and effects on allergy-related health outcomes |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/UVRI and LSHTM Research Unit Uganda |
| Country | Uganda |
| Sector | Academic/University |
| PI Contribution | Contributed to trial design. Currently leading statistical analysis |
| Collaborator Contribution | Trial leadership and all other aspects |
| Impact | Protocol paper submitted to Trials, baseline findings presented at the European Academy of Allergy and Clinical Immunology (EAACI) conference in June 2014. Intervention is currently ongoing. |
| Start Year | 2011 |
| Description | Clinical Trial: HIV combination prevention (PopArt) |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Chief Investigator; Trial design; Protocol development; Trial Statistician; Supervision; Administration |
| Collaborator Contribution | Trial is carried out in partnership with NIH HIV Prevention Trials Network; Trial management, laboratory activities and data management and analysis supported by HPTN Core, Network Laboratory and Data and Statistics Center; Field work coordinated at Zambart and DTTC; Modelling and economics components coordinated by Imperial College. |
| Impact | Funding for trial secured, research group established, protocol version 1.0 approved, IRB submissions |
| Start Year | 2011 |
| Description | Clinical Trial: HIV combination prevention (PopArt) |
| Organisation | National Institutes of Health (NIH) |
| Department | HIV Prevention Trials Network HPTN |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Chief Investigator; Trial design; Protocol development; Trial Statistician; Supervision; Administration |
| Collaborator Contribution | Trial is carried out in partnership with NIH HIV Prevention Trials Network; Trial management, laboratory activities and data management and analysis supported by HPTN Core, Network Laboratory and Data and Statistics Center; Field work coordinated at Zambart and DTTC; Modelling and economics components coordinated by Imperial College. |
| Impact | Funding for trial secured, research group established, protocol version 1.0 approved, IRB submissions |
| Start Year | 2011 |
| Description | Clinical Trial: HIV combination prevention (PopArt) |
| Organisation | University of Stellenbosch |
| Department | Desmond Tutu TB Centre |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Chief Investigator; Trial design; Protocol development; Trial Statistician; Supervision; Administration |
| Collaborator Contribution | Trial is carried out in partnership with NIH HIV Prevention Trials Network; Trial management, laboratory activities and data management and analysis supported by HPTN Core, Network Laboratory and Data and Statistics Center; Field work coordinated at Zambart and DTTC; Modelling and economics components coordinated by Imperial College. |
| Impact | Funding for trial secured, research group established, protocol version 1.0 approved, IRB submissions |
| Start Year | 2011 |
| Description | Clinical Trial: HIV combination prevention (PopArt) |
| Organisation | Zambia AIDS Related Tuberculosis |
| Country | Zambia |
| Sector | Academic/University |
| PI Contribution | Chief Investigator; Trial design; Protocol development; Trial Statistician; Supervision; Administration |
| Collaborator Contribution | Trial is carried out in partnership with NIH HIV Prevention Trials Network; Trial management, laboratory activities and data management and analysis supported by HPTN Core, Network Laboratory and Data and Statistics Center; Field work coordinated at Zambart and DTTC; Modelling and economics components coordinated by Imperial College. |
| Impact | Funding for trial secured, research group established, protocol version 1.0 approved, IRB submissions |
| Start Year | 2011 |
| Description | Clinical Trial: TB Fast Track: a cluster randomised trial to evaluate the effect of a point-of-care TB test-and-treat algorithm on early mortality in people with HIV accessing ART |
| Organisation | Aurum Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Funding for trial secured; research group established; protocol and CRFs drafted; trial started. Recruitment to end in Dec 2014. Symposium at the Union TB conference in Barcelona 2014 on empiric TB treatment organised by TB Fast Track investigators |
| Start Year | 2012 |
| Description | Clinical Trial: TB Fast Track: a cluster randomised trial to evaluate the effect of a point-of-care TB test-and-treat algorithm on early mortality in people with HIV accessing ART |
| Organisation | Foundation for Professional Development |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Funding for trial secured; research group established; protocol and CRFs drafted; trial started. Recruitment to end in Dec 2014. Symposium at the Union TB conference in Barcelona 2014 on empiric TB treatment organised by TB Fast Track investigators |
| Start Year | 2012 |
| Description | Clinical Trial: TB Fast Track: a cluster randomised trial to evaluate the effect of a point-of-care TB test-and-treat algorithm on early mortality in people with HIV accessing ART |
| Organisation | Johns Hopkins University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Funding for trial secured; research group established; protocol and CRFs drafted; trial started. Recruitment to end in Dec 2014. Symposium at the Union TB conference in Barcelona 2014 on empiric TB treatment organised by TB Fast Track investigators |
| Start Year | 2012 |
| Description | Clinical trial: Impact of helminths on the response to immunisation and on incidence of infection and disease in childhood |
| Organisation | Entebbe District Hospital |
| Country | Uganda |
| Sector | Hospitals |
| PI Contribution | Designed and supported randomised trial evaluating 3 interventions at 2 stages. |
| Collaborator Contribution | Trial leadership; Access to study cohort |
| Impact | Trial found that anthelminthic treatment during pregnancy increased incidence of eczema in childhood, and that quarterly anthelminthic treatment during early childhood decreased the incidence of malaria. Apart from this, there were no other effects of anthelminthic treatment during pregnancy and childhood on responses to immunisations, incidence of infectious diseases, growth or anaemia. Main trial results have been published in the Lancet and in PLoS ONE. Children are now being follow-up to 10 years old. |
| Start Year | 2006 |
| Description | Clinical trial: Impact of helminths on the response to immunisation and on incidence of infection and disease in childhood |
| Organisation | MRC/UVRI Uganda Research Unit on AIDS |
| Country | Uganda |
| Sector | Public |
| PI Contribution | Designed and supported randomised trial evaluating 3 interventions at 2 stages. |
| Collaborator Contribution | Trial leadership; Access to study cohort |
| Impact | Trial found that anthelminthic treatment during pregnancy increased incidence of eczema in childhood, and that quarterly anthelminthic treatment during early childhood decreased the incidence of malaria. Apart from this, there were no other effects of anthelminthic treatment during pregnancy and childhood on responses to immunisations, incidence of infectious diseases, growth or anaemia. Main trial results have been published in the Lancet and in PLoS ONE. Children are now being follow-up to 10 years old. |
| Start Year | 2006 |
| Description | Clinical trial: Implementation and evaluation of an optimized model for scaling up TB/HIV integration at primary care clinics in Ekurhuleni north sub-district, South Africa |
| Organisation | Aurum Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Protocol and CRFs drafted; trial completed and data currently being analysed. Paper published on trial design (Contemporary Clinical Trials 2014) |
| Start Year | 2011 |
| Description | Clinical trial: Xpert MTB/RIF for diagnosis of tuberculosis: evaluating impact and cost-effectiveness in the routine roll-out in South Africa "Xpert for TB: Evaluating a New Diagnostic" (XTEND) trial and XPHACTOR study |
| Organisation | Aurum Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Funding for trial secured; research group established; protocol and CRFs drafted; trial started. XTEND trial completed and results presented at CROI (2014) and South Africa TB conference (2014). Main paper under review and other papers in progress. XPHACTOR recruitment and follow-up completed, data currently being analysed. Interim data presented at South Africa TB (2014) and Union TB Conference (2014); Papers in progress. |
| Start Year | 2011 |
| Description | Clinical trial: Xpert MTB/RIF for diagnosis of tuberculosis: evaluating impact and cost-effectiveness in the routine roll-out in South Africa "Xpert for TB: Evaluating a New Diagnostic" (XTEND) trial and XPHACTOR study |
| Organisation | National Health Laboratory Services, South Africa |
| Country | South Africa |
| Sector | Public |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Funding for trial secured; research group established; protocol and CRFs drafted; trial started. XTEND trial completed and results presented at CROI (2014) and South Africa TB conference (2014). Main paper under review and other papers in progress. XPHACTOR recruitment and follow-up completed, data currently being analysed. Interim data presented at South Africa TB (2014) and Union TB Conference (2014); Papers in progress. |
| Start Year | 2011 |
| Description | Clinical trial: Xpert MTB/RIF for diagnosis of tuberculosis: evaluating impact and cost-effectiveness in the routine roll-out in South Africa "Xpert for TB: Evaluating a New Diagnostic" (XTEND) trial and XPHACTOR study |
| Organisation | University of Cape Town |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Funding for trial secured; research group established; protocol and CRFs drafted; trial started. XTEND trial completed and results presented at CROI (2014) and South Africa TB conference (2014). Main paper under review and other papers in progress. XPHACTOR recruitment and follow-up completed, data currently being analysed. Interim data presented at South Africa TB (2014) and Union TB Conference (2014); Papers in progress. |
| Start Year | 2011 |
| Description | Clinical trial: Xpert MTB/RIF for diagnosis of tuberculosis: evaluating impact and cost-effectiveness in the routine roll-out in South Africa "Xpert for TB: Evaluating a New Diagnostic" (XTEND) trial and XPHACTOR study |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Funding for trial secured; research group established; protocol and CRFs drafted; trial started. XTEND trial completed and results presented at CROI (2014) and South Africa TB conference (2014). Main paper under review and other papers in progress. XPHACTOR recruitment and follow-up completed, data currently being analysed. Interim data presented at South Africa TB (2014) and Union TB Conference (2014); Papers in progress. |
| Start Year | 2011 |
| Description | Collaborative group on the impact of digital technologies on TB |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | Contributed to a paper titled "Digital health technologies for active TB treatment support: A cost-effectiveness analysis" as part of the collaborative group, led by WHO |
| Collaborator Contribution | WHO lead the collaborative group |
| Impact | One publication submitted to a journal |
| Start Year | 2017 |
| Description | Combined HIV Adolescent PrEP and Prevention Study |
| Organisation | Wits Health Consortium |
| Country | South Africa |
| Sector | Private |
| PI Contribution | Study design, sample size, statistical analysis |
| Collaborator Contribution | Laboratory analysis, field work, data collection, study design, scientific hypothesis |
| Impact | Poster presented at HIVR4P, Oct 2018: http://apps.webofknowledge.com/InboundService.do?customersID=LinksAMR&mode=FullRecord&IsProductCode=Yes?uct=WOS&Init=Yes&Func=Frame&DestFail=http%3A%2F%2Fwww.webofknowledge.com?tion=retrieve&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&SID=C2bwzliNPISkWLdNkIt&UT=WOS%3A000448371600674 Multi-disciplinary: Epidemiology, social science, clinical trial, laboratory |
| Start Year | 2018 |
| Description | DIAMA |
| Organisation | National Hospital of Pneumo-Phtisiology |
| Country | Benin |
| Sector | Hospitals |
| PI Contribution | LSHTM lead on statistical analysis, contribution to data management and paper writing |
| Collaborator Contribution | Coordination, study design, implementation, paper writing |
| Impact | None yet |
| Start Year | 2016 |
| Description | DIVIDS study and follow-ups |
| Organisation | University of Delhi |
| Department | Institute of Home Economics |
| Country | India |
| Sector | Academic/University |
| PI Contribution | Analysis of RCT of vitamin D supplementation to low birth weight term infants. Analysis of follow-up data from 4-5 year olds |
| Collaborator Contribution | Co-ordination of the field work |
| Impact | Analysis of main trial result in BMJ. Follow-up data was published in Int J Epi and BMJ Open. Multi-disciplinary - nutrition. |
| Start Year | 2010 |
| Description | DREAMS evaluation |
| Organisation | African Population and Health Research Center |
| Country | Kenya |
| Sector | Academic/University |
| PI Contribution | co-Principal investigator |
| Collaborator Contribution | Co-design of impact evaluation design, new research questionnaires, lead responsibility for field implementation |
| Impact | Presentations (oral and poster) at AIDS Impact conference 2017 and R4P 2018. Plos One journal supplement with papers reporting historical trends and baseline findings. Protocol paper published. Multi-disciplinary: Epidemiology, Demography, Public Health, Social Science |
| Start Year | 2016 |
| Description | DREAMS evaluation |
| Organisation | Armauer Hansen Research Institute |
| Country | Ethiopia |
| Sector | Charity/Non Profit |
| PI Contribution | co-Principal investigator |
| Collaborator Contribution | Co-design of impact evaluation design, new research questionnaires, lead responsibility for field implementation |
| Impact | Presentations (oral and poster) at AIDS Impact conference 2017 and R4P 2018. Plos One journal supplement with papers reporting historical trends and baseline findings. Protocol paper published. Multi-disciplinary: Epidemiology, Demography, Public Health, Social Science |
| Start Year | 2016 |
| Description | DREAMS evaluation |
| Organisation | Centre for Sexual Health and HIV AIDS Research Zimbabwe (CeSHHAR Zimbabwe) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | co-Principal investigator |
| Collaborator Contribution | Co-design of impact evaluation design, new research questionnaires, lead responsibility for field implementation |
| Impact | Presentations (oral and poster) at AIDS Impact conference 2017 and R4P 2018. Plos One journal supplement with papers reporting historical trends and baseline findings. Protocol paper published. Multi-disciplinary: Epidemiology, Demography, Public Health, Social Science |
| Start Year | 2016 |
| Description | DREAMS evaluation |
| Organisation | Kenyan Institute for Medical Research (KEMRI) |
| Country | Kenya |
| Sector | Public |
| PI Contribution | co-Principal investigator |
| Collaborator Contribution | Co-design of impact evaluation design, new research questionnaires, lead responsibility for field implementation |
| Impact | Presentations (oral and poster) at AIDS Impact conference 2017 and R4P 2018. Plos One journal supplement with papers reporting historical trends and baseline findings. Protocol paper published. Multi-disciplinary: Epidemiology, Demography, Public Health, Social Science |
| Start Year | 2016 |
| Description | DREAMS evaluation |
| Organisation | United States President's Emergency Plan for AIDS Relief |
| Country | United States |
| Sector | Public |
| PI Contribution | co-Principal investigator |
| Collaborator Contribution | Co-design of impact evaluation design, new research questionnaires, lead responsibility for field implementation |
| Impact | Presentations (oral and poster) at AIDS Impact conference 2017 and R4P 2018. Plos One journal supplement with papers reporting historical trends and baseline findings. Protocol paper published. Multi-disciplinary: Epidemiology, Demography, Public Health, Social Science |
| Start Year | 2016 |
| Description | Dengue Index |
| Organisation | Khon Kaen University |
| Country | Thailand |
| Sector | Academic/University |
| PI Contribution | Design and analysis of case-control study and cluster-randomized trial |
| Collaborator Contribution | Carrying out clinical and entomological investigations in clinics and homes |
| Impact | Multi-disciplinary: Entomology, public health |
| Start Year | 2016 |
| Description | Dengue Index |
| Organisation | Norwegian University of Life Sciences (NMBU) |
| Country | Norway |
| Sector | Academic/University |
| PI Contribution | Design and analysis of case-control study and cluster-randomized trial |
| Collaborator Contribution | Carrying out clinical and entomological investigations in clinics and homes |
| Impact | Multi-disciplinary: Entomology, public health |
| Start Year | 2016 |
| Description | Design and analysis of clinical trials for the treatment of Visceral Leishmaniasis |
| Organisation | Drugs for Neglected Diseases initiative (DNDi) |
| Country | Switzerland |
| Sector | Charity/Non Profit |
| PI Contribution | Contributed to design and analysis of clinical trials, continued capacity building in data management, study design and analysis methods, preparation of successful grant applications, project management |
| Collaborator Contribution | Sponsorship of clinical trials, intellectual input, project management, leadership |
| Impact | Trials ongoing. Demonstration of ability to conduct rigorous research in the context of a public health emergency and engage affected communities in a volatile stigmatised environment. Multi-disciplinary - Statistics, clinical, public health. |
| Start Year | 2013 |
| Description | Design and analysis of clinical trials for the treatment of Visceral Leishmaniasis |
| Organisation | Institute of Tropical Medicine Antwerp |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | Contributed to design and analysis of clinical trials, continued capacity building in data management, study design and analysis methods, preparation of successful grant applications, project management |
| Collaborator Contribution | Sponsorship of clinical trials, intellectual input, project management, leadership |
| Impact | Trials ongoing. Demonstration of ability to conduct rigorous research in the context of a public health emergency and engage affected communities in a volatile stigmatised environment. Multi-disciplinary - Statistics, clinical, public health. |
| Start Year | 2013 |
| Description | Design and analysis of clinical trials for the treatment of Visceral Leishmaniasis |
| Organisation | Leishmaniasis East Africa Platform (LEAP) |
| Country | Sudan |
| Sector | Public |
| PI Contribution | Contributed to design and analysis of clinical trials, continued capacity building in data management, study design and analysis methods, preparation of successful grant applications, project management |
| Collaborator Contribution | Sponsorship of clinical trials, intellectual input, project management, leadership |
| Impact | Trials ongoing. Demonstration of ability to conduct rigorous research in the context of a public health emergency and engage affected communities in a volatile stigmatised environment. Multi-disciplinary - Statistics, clinical, public health. |
| Start Year | 2013 |
| Description | Drought, Poverty and HIV Drug Resistance: threat to resilience in a vulnerable rural settings |
| Organisation | Africa Health Research Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | study design; statistical advice, data linkage; analysis |
| Collaborator Contribution | study design; coordination; field work; spatial epidemiology; economic modelling; climate science |
| Impact | None yet. Multidisciplinary: epidemiology, public health, climate science, biostatistics, qualitative research |
| Start Year | 2017 |
| Description | Drought, Poverty and HIV Drug Resistance: threat to resilience in a vulnerable rural settings |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | study design; statistical advice, data linkage; analysis |
| Collaborator Contribution | study design; coordination; field work; spatial epidemiology; economic modelling; climate science |
| Impact | None yet. Multidisciplinary: epidemiology, public health, climate science, biostatistics, qualitative research |
| Start Year | 2017 |
| Description | Drought, Poverty and HIV Drug Resistance: threat to resilience in a vulnerable rural settings |
| Organisation | University of Sussex |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | study design; statistical advice, data linkage; analysis |
| Collaborator Contribution | study design; coordination; field work; spatial epidemiology; economic modelling; climate science |
| Impact | None yet. Multidisciplinary: epidemiology, public health, climate science, biostatistics, qualitative research |
| Start Year | 2017 |
| Description | EIP trial |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/UVRI and LSHTM Research Unit Uganda |
| Country | Uganda |
| Sector | Academic/University |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary - Epidemiology, public health |
| Start Year | 2017 |
| Description | Eave Tubes |
| Organisation | Cote D'Ivoire's National Institute of Public Health |
| Country | Cote d'Ivoire |
| Sector | Public |
| PI Contribution | Project statistician/epidemiologist- co-design of study and analysis; coordination with sample collection and fieldwork |
| Collaborator Contribution | co-design; development of novel vector control product; field activities; entomological activities; lab analysis of samples |
| Impact | Multi-disciplinary: epidemiology, public health, social science, entomology |
| Start Year | 2016 |
| Description | Eave Tubes |
| Organisation | In2Care BV |
| Country | Netherlands |
| Sector | Private |
| PI Contribution | Project statistician/epidemiologist- co-design of study and analysis; coordination with sample collection and fieldwork |
| Collaborator Contribution | co-design; development of novel vector control product; field activities; entomological activities; lab analysis of samples |
| Impact | Multi-disciplinary: epidemiology, public health, social science, entomology |
| Start Year | 2016 |
| Description | Eave Tubes |
| Organisation | Penn State University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Project statistician/epidemiologist- co-design of study and analysis; coordination with sample collection and fieldwork |
| Collaborator Contribution | co-design; development of novel vector control product; field activities; entomological activities; lab analysis of samples |
| Impact | Multi-disciplinary: epidemiology, public health, social science, entomology |
| Start Year | 2016 |
| Description | Eliminate Dengue Program |
| Organisation | Monash University |
| Department | Eliminate Dengue Program |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Design of cluster randomised trial to evaluate effectiveness of large scale Wolbachia deployments on dengue transmission |
| Collaborator Contribution | Facilitation and hosting of three workshops to design and plan trials in Indonesia and Vietnam |
| Impact | Study protocol and draft manuscript on trial design. Multi-disciplinary - Epidemiology, Entomology, Infectious Disease Control, Statistics, Modelling. |
| Start Year | 2015 |
| Description | Elimination Eight Partnerships |
| Organisation | Elimination Eight |
| Country | Namibia |
| Sector | Private |
| PI Contribution | Technical advice and leadership for malaria elimination in 8 SADC countries |
| Collaborator Contribution | Co-ordination of regional malaria elimnation strategies |
| Impact | Multi-disciplinary: Epidemiology, Public Health |
| Start Year | 2016 |
| Description | Epidemiology of alcohol use and alcohol use disorders among young people in northern Tanzania |
| Organisation | National Institute for Medical Research, Tanzania |
| Department | NIMR Dar Es Salaam |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | PhD supervision (study design and supervision of analysis) |
| Collaborator Contribution | Study design, co-ordination and analysis |
| Impact | 4 papers published - included in publication section on researchfish submission. Multi-disciplinary: epidemiology, public health |
| Start Year | 2011 |
| Description | Epidemiology of microcephaly and Zika in Pernambuco, Brasil |
| Organisation | Oswaldo Cruz Foundation (Fiocruz) |
| Country | Brazil |
| Sector | Public |
| PI Contribution | Space/time analysis of data on incidence of microcephaly; estimation of incidence of Zika, |
| Collaborator Contribution | Multiple population and hospital-based studies on microcephaly and Zika. |
| Impact | None as yet. |
| Start Year | 2016 |
| Description | Evaluation of an mHealth app for Ebola contact tracing |
| Organisation | Innovations for Poverty Action (IPA) |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Design & analysis of a smartphone app to improve contact tracing and monitoring during the 2015 Ebola outbreak in Sierra Leone |
| Collaborator Contribution | Development of the app |
| Impact | Final analysis is ongoing. Multi disciplinary - Epidemiology, social science, technology |
| Start Year | 2015 |
| Description | Evaluation of attractant targeted sugar baits for malaria prevention |
| Organisation | University of Bamako |
| Country | Mali |
| Sector | Academic/University |
| PI Contribution | study design, protocol development, trial support, statistical analysis |
| Collaborator Contribution | Entomology, sugar bait technology, fieldwork experience |
| Impact | Multi-disciplinary: epidemiology, entomology, statistics, social science |
| Start Year | 2018 |
| Description | Evaluation of convalescent Plasma for Ebola Virus Disease in Sierra Leone |
| Organisation | Institute of Tropical Medicine Antwerp |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | Contributing to design and analysis of clinical trials, preparation of successful grant applications, project management |
| Collaborator Contribution | Sponsorship of clinical trials, intellectual input, project management, leadership |
| Impact | Publication of trial findings in New England Journal of Medicine. Multi-disciplinary - Statistics, clinical, public health. |
| Start Year | 2014 |
| Description | Evaluation of convalescent Plasma for Ebola Virus Disease in Sierra Leone |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contributing to design and analysis of clinical trials, preparation of successful grant applications, project management |
| Collaborator Contribution | Sponsorship of clinical trials, intellectual input, project management, leadership |
| Impact | Publication of trial findings in New England Journal of Medicine. Multi-disciplinary - Statistics, clinical, public health. |
| Start Year | 2014 |
| Description | Friendship Bench |
| Organisation | University of Zimbabwe |
| Country | Zimbabwe |
| Sector | Academic/University |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health 3 papers published, details in publications section of researchfish submission Outcome - Scale-up of the Friendship Bench in Zimbabwe |
| Start Year | 2013 |
| Description | GIS training |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Unit, The Gambia |
| Country | Gambia |
| Sector | Public |
| PI Contribution | Developed material and gave training course at each institution |
| Collaborator Contribution | Fieldwork during training |
| Impact | Multi-disciplinary: GIS, epidemiology, statistics |
| Start Year | 2018 |
| Description | GIS training |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/UVRI and LSHTM Research Unit Uganda |
| Country | Uganda |
| Sector | Academic/University |
| PI Contribution | Developed material and gave training course at each institution |
| Collaborator Contribution | Fieldwork during training |
| Impact | Multi-disciplinary: GIS, epidemiology, statistics |
| Start Year | 2018 |
| Description | GMZ2 Consortium |
| Organisation | Center of Medical Research Lambaréné |
| Country | Gabon |
| Sector | Academic/University |
| PI Contribution | Design and analysis of the GMZ2 malaria vaccine trial |
| Collaborator Contribution | Co-ordination of the field trial |
| Impact | Final efficacy analysis is ongoing. This is a multi centre phase 2b vaccine trial so involves clinical, epidemiological, statistical and laboratory (immunology) expertise. |
| Start Year | 2008 |
| Description | GMZ2 Consortium |
| Organisation | Makerere University College of Health Sciences |
| Country | Uganda |
| Sector | Academic/University |
| PI Contribution | Design and analysis of the GMZ2 malaria vaccine trial |
| Collaborator Contribution | Co-ordination of the field trial |
| Impact | Final efficacy analysis is ongoing. This is a multi centre phase 2b vaccine trial so involves clinical, epidemiological, statistical and laboratory (immunology) expertise. |
| Start Year | 2008 |
| Description | GMZ2 Consortium |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Unit, The Gambia |
| Country | Gambia |
| Sector | Public |
| PI Contribution | Design and analysis of the GMZ2 malaria vaccine trial |
| Collaborator Contribution | Co-ordination of the field trial |
| Impact | Final efficacy analysis is ongoing. This is a multi centre phase 2b vaccine trial so involves clinical, epidemiological, statistical and laboratory (immunology) expertise. |
| Start Year | 2008 |
| Description | GMZ2 Consortium |
| Organisation | Navrongo Health Research Centre (NHRC) |
| Country | Ghana |
| Sector | Academic/University |
| PI Contribution | Design and analysis of the GMZ2 malaria vaccine trial |
| Collaborator Contribution | Co-ordination of the field trial |
| Impact | Final efficacy analysis is ongoing. This is a multi centre phase 2b vaccine trial so involves clinical, epidemiological, statistical and laboratory (immunology) expertise. |
| Start Year | 2008 |
| Description | GMZ2 Consortium |
| Organisation | The Statens Serum Institute (SSI) |
| Country | Denmark |
| Sector | Public |
| PI Contribution | Design and analysis of the GMZ2 malaria vaccine trial |
| Collaborator Contribution | Co-ordination of the field trial |
| Impact | Final efficacy analysis is ongoing. This is a multi centre phase 2b vaccine trial so involves clinical, epidemiological, statistical and laboratory (immunology) expertise. |
| Start Year | 2008 |
| Description | Global mental health trials |
| Organisation | Sangath |
| Country | India |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical and epidemiological collaboration |
| Collaborator Contribution | Leadership and all aspects of the trials |
| Impact | Evidence to support the use of lay health workers in delivering psychosocial interventions in primary care clinics. Multi disciplinary - Epidemiology, statistics, clinical, public health |
| Description | Gnatwork |
| Organisation | The Pirbright Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Setting up grant schemes, reviewing the resultant proposals, and training. |
| Collaborator Contribution | As previous, plus administering the core scheme and the grants awarded. |
| Impact | Multi-disciplinary: epidemiology, entomology, statistics, molecular biology |
| Start Year | 2017 |
| Description | Good Health for Women Project |
| Organisation | MRC/UVRI Uganda Research Unit on AIDS |
| Country | Uganda |
| Sector | Public |
| PI Contribution | Analysis of a long-term cohort of women at high risk of HIV |
| Collaborator Contribution | Study co-ordination |
| Impact | Multi-disciplinary: epidemiology, social science |
| Start Year | 2016 |
| Description | HAYA |
| Organisation | Africa Health Research Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Suzanna Francis was Principal investigator leading the iGugu project |
| Collaborator Contribution | Study was co-run with partners |
| Impact | 1 paper; 4 conference presentations. Disciplines involved - Epidemiology; Social Science; Laboratory Science |
| Start Year | 2015 |
| Description | HC-HIV IPD |
| Organisation | Family Health International |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Protocol development and review of analysis and paper |
| Collaborator Contribution | FHI was leading the project and carried out the analysis |
| Impact | 1 paper. Impact: Impacted WHO policy on contraceptive use among women at high risk for HIV |
| Start Year | 2012 |
| Description | HCBV |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Suzanna Francis is principal investigator |
| Collaborator Contribution | 16SrRNA sequencing; metabolomics; Luminex testing; data collection |
| Impact | No outputs yet. Disciplines include Epidemiology; Social Science; Laboratory Science |
| Start Year | 2017 |
| Description | HCBV |
| Organisation | MRC/UVRI Uganda Research Unit on AIDS |
| Country | Uganda |
| Sector | Public |
| PI Contribution | Suzanna Francis is principal investigator |
| Collaborator Contribution | 16SrRNA sequencing; metabolomics; Luminex testing; data collection |
| Impact | No outputs yet. Disciplines include Epidemiology; Social Science; Laboratory Science |
| Start Year | 2017 |
| Description | HCBV |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Suzanna Francis is principal investigator |
| Collaborator Contribution | 16SrRNA sequencing; metabolomics; Luminex testing; data collection |
| Impact | No outputs yet. Disciplines include Epidemiology; Social Science; Laboratory Science |
| Start Year | 2017 |
| Description | HDTstudy |
| Organisation | Aurum Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Study design and supervising analysis |
| Collaborator Contribution | Study design, co-ordination, trial recruitment |
| Impact | Multi-disciplinary: statistics, trial design, immunology |
| Start Year | 2016 |
| Description | HIV Drug Resistance Elimination And Management Network |
| Organisation | Africa Health Research Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | study design; statistical advice, data linkage; analysis |
| Collaborator Contribution | study design; coordination; field activities; organisation of workships; |
| Impact | None yet. Multidisciplinary: epidemiology, public health, statistics, qualitative research |
| Start Year | 2017 |
| Description | HIV Drug Resistance Elimination And Management Network |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | study design; statistical advice, data linkage; analysis |
| Collaborator Contribution | study design; coordination; field activities; organisation of workships; |
| Impact | None yet. Multidisciplinary: epidemiology, public health, statistics, qualitative research |
| Start Year | 2017 |
| Description | HIV Drug Resistance Elimination And Management Network |
| Organisation | University of Sussex |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | study design; statistical advice, data linkage; analysis |
| Collaborator Contribution | study design; coordination; field activities; organisation of workships; |
| Impact | None yet. Multidisciplinary: epidemiology, public health, statistics, qualitative research |
| Start Year | 2017 |
| Description | HIV Prevention Trials |
| Organisation | WellcomeTrust Africa Centre |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical collaboration at Africa Centre |
| Collaborator Contribution | Leadership of Africa Centre |
| Impact | Renewal of Africa Centre grant from Wellcome Trust. Multi-disciplinary - Epidemiology, statistics, economics, social science, clinical medicine, molecular biology |
| Start Year | 2014 |
| Description | HIV Self-Testing in AfRica (STAR) |
| Organisation | Centre for Sexual Health and HIV AIDS Research Zimbabwe (CeSHHAR Zimbabwe) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2015 |
| Description | HIV Self-Testing in AfRica (STAR) |
| Organisation | Liverpool School of Tropical Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2015 |
| Description | HIV Self-Testing in AfRica (STAR) |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2015 |
| Description | HIV Self-Testing in AfRica (STAR) |
| Organisation | Wellcome Trust |
| Department | Malawi-Liverpool Wellcome Trust Clinical Research Programme |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2015 |
| Description | HIV Self-Testing in AfRica (STAR) |
| Organisation | World Health Organization (WHO) |
| Department | UNITAID |
| Country | Switzerland |
| Sector | Public |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2015 |
| Description | HIV epidemiology in the Middle East and North Africa |
| Organisation | Weill Cornell Medical College in Qatar |
| Country | Qatar |
| Sector | Academic/University |
| PI Contribution | PhD supervision |
| Collaborator Contribution | Analysis and modelling |
| Impact | 4 papers published, details in publications section of submission Multi-disciplinary: epidemiology, modelling |
| Start Year | 2012 |
| Description | HIV self testing: Network distribution for linkage to PrEP and prevention in South Africa (AHRI) |
| Organisation | Africa Health Research Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | study design, sample size, statistical analysis |
| Collaborator Contribution | study design, field activities |
| Impact | Multi-disciplinary: epidemiology, statistics, social science |
| Start Year | 2017 |
| Description | HIV self testing: Network distribution for linkage to PrEP and prevention in South Africa (AHRI) |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | study design, sample size, statistical analysis |
| Collaborator Contribution | study design, field activities |
| Impact | Multi-disciplinary: epidemiology, statistics, social science |
| Start Year | 2017 |
| Description | HIV/VL India |
| Organisation | Médecins Sans Frontières (MSF) |
| Country | France |
| Sector | Charity/Non Profit |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Leading clinical trial of drugs against visceral leishmaniasis in HIV co-infected patients |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2016 |
| Description | HPV Vaccine Trial - DoRIS |
| Organisation | University of York |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Member of the team funded by this award is a PI on the grant. |
| Collaborator Contribution | Co-investigator on grant; immunology assays for vaccine trial |
| Impact | None yet |
| Start Year | 2016 |
| Description | HPV vaccine trial - DoRIS |
| Organisation | Catalan Institute of Oncology (ICO) |
| Department | Cancer Epidemiology Research Programme (PREC) |
| Country | Spain |
| Sector | Hospitals |
| PI Contribution | Member of the team is PI on this grant. |
| Collaborator Contribution | co-investigator on grant; HPV assays for vaccine trial |
| Impact | None yet |
| Start Year | 2016 |
| Description | HPV vaccine trial - DoRIS |
| Organisation | Karolinska Institute |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Member of research team is PI on this grant. |
| Collaborator Contribution | co-investigator on grant; immunology assays for vaccine trial |
| Impact | None yet |
| Start Year | 2016 |
| Description | HPV vaccine trial - DoRIS |
| Organisation | National Institutes of Health (NIH) |
| Department | National Cancer Institute (NCI) |
| Country | United States |
| Sector | Public |
| PI Contribution | Member of team is PI on this grant |
| Collaborator Contribution | co-investigator on grant; immunology assays for vaccine trial |
| Impact | None yet |
| Start Year | 2016 |
| Description | HPV vaccine trial - DoRIS |
| Organisation | National Institutes of Health (NIH) |
| Country | United States |
| Sector | Public |
| PI Contribution | sharing of HPV vaccine immunogenicity data |
| Collaborator Contribution | sharing of HPV vaccine efficacy data for immunobridging |
| Impact | None yet |
| Start Year | 2016 |
| Description | HomeACF |
| Organisation | University of the Witwatersrand |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: public health, health economics, statistics |
| Start Year | 2016 |
| Description | IRD TB Programme Evaluation |
| Organisation | IRD Global |
| Country | Pakistan |
| Sector | Charity/Non Profit |
| PI Contribution | Co-design of evaluation of TB control programme through prevalence surveys and will do the analysis |
| Collaborator Contribution | Co-design and running of evaluation |
| Impact | Multi-disciplinary: Epidemiology, public health, statistics |
| Start Year | 2016 |
| Description | IVM Malaysia |
| Organisation | Bayer |
| Department | Bayer CropScience Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Study design and analysis |
| Collaborator Contribution | As previous, plus field and lab work. |
| Impact | Multi-disciplinary: epidemiology, entomology, statistics, public health, social science |
| Start Year | 2017 |
| Description | Ilorin-Gambia-LSHTM group on sickle cell disease |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Unit, The Gambia |
| Country | Gambia |
| Sector | Public |
| PI Contribution | Design and coordination of the randomized trial |
| Collaborator Contribution | Conducted the clinic-based trial |
| Impact | Evidence to support policy change for the management of sickle cell patients in malaria endemic areas. This collaboration is multi-disciplinary involving clinical medicine, epidemioogy, statistics, molecular biology. |
| Start Year | 2010 |
| Description | Ilorin-Gambia-LSHTM group on sickle cell disease |
| Organisation | University of Ilorin Teaching Hospital, Nigeria |
| Country | Nigeria |
| Sector | Academic/University |
| PI Contribution | Design and coordination of the randomized trial |
| Collaborator Contribution | Conducted the clinic-based trial |
| Impact | Evidence to support policy change for the management of sickle cell patients in malaria endemic areas. This collaboration is multi-disciplinary involving clinical medicine, epidemioogy, statistics, molecular biology. |
| Start Year | 2010 |
| Description | Improving the health systems response to chronic diseases in Africa |
| Organisation | MRC/UVRI Uganda Research Unit on AIDS |
| Country | Uganda |
| Sector | Public |
| PI Contribution | Statistical support - analysis, reporting of results. PI and Tanzania PI based at MITU; study co-run by MITU |
| Collaborator Contribution | Study co-run by MRC Uganda |
| Impact | Number of manuscripts phase 1 (surveys): published 8. Phase 2: 2 papers in preparation. 1 book chapter published. Impacted on NCD control practice in Uganda and Tanzania. E.g. Tz introduced position of district NCD coordinators, District Mos allocated funds to purchase of NCD drugs. (These impacts are tangible but direct link to project difficult to prove). |
| Start Year | 2011 |
| Description | Improving the health systems response to chronic diseases in Africa |
| Organisation | Ministry of Health and Social Welfare |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | Statistical support - analysis, reporting of results. PI and Tanzania PI based at MITU; study co-run by MITU |
| Collaborator Contribution | Study co-run by MRC Uganda |
| Impact | Number of manuscripts phase 1 (surveys): published 8. Phase 2: 2 papers in preparation. 1 book chapter published. Impacted on NCD control practice in Uganda and Tanzania. E.g. Tz introduced position of district NCD coordinators, District Mos allocated funds to purchase of NCD drugs. (These impacts are tangible but direct link to project difficult to prove). |
| Start Year | 2011 |
| Description | Improving the health systems response to chronic diseases in Africa |
| Organisation | National Institute for Medical Research, Tanzania |
| Department | Mwanza Intervention Trials Unit (MITU) |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | Statistical support - analysis, reporting of results. PI and Tanzania PI based at MITU; study co-run by MITU |
| Collaborator Contribution | Study co-run by MRC Uganda |
| Impact | Number of manuscripts phase 1 (surveys): published 8. Phase 2: 2 papers in preparation. 1 book chapter published. Impacted on NCD control practice in Uganda and Tanzania. E.g. Tz introduced position of district NCD coordinators, District Mos allocated funds to purchase of NCD drugs. (These impacts are tangible but direct link to project difficult to prove). |
| Start Year | 2011 |
| Description | Infection prevention and control for drug-resistant tuberculosis in South Africa (AHRI) |
| Organisation | Africa Health Research Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | sample size, study design, statistical analysis, sampling |
| Collaborator Contribution | study design, analysis, field activities |
| Impact | Multi-disciplinary: epidemiology, statistics, modelling, social science |
| Start Year | 2017 |
| Description | Leaving no-one behind |
| Organisation | MRC/UVRI Uganda Research Unit on AIDS |
| Country | Uganda |
| Sector | Public |
| PI Contribution | Co-investigator |
| Collaborator Contribution | Study co-ordination and analysis |
| Impact | Discipline: social science |
| Start Year | 2016 |
| Description | Lung disease in HIV infected children |
| Organisation | Biomedical Research and Training Institute (BRTI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical and epidemiological collaboration |
| Collaborator Contribution | Leadership and all aspects of the trial |
| Impact | Trial initiating in 2016. |
| Start Year | 2014 |
| Description | Lung disease in HIV infected children |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Statistical and epidemiological collaboration |
| Collaborator Contribution | Leadership and all aspects of the trial |
| Impact | Trial initiating in 2016. |
| Start Year | 2014 |
| Description | Lung disease in HIV infected children |
| Organisation | University of Tromso |
| Country | Norway |
| Sector | Academic/University |
| PI Contribution | Statistical and epidemiological collaboration |
| Collaborator Contribution | Leadership and all aspects of the trial |
| Impact | Trial initiating in 2016. |
| Start Year | 2014 |
| Description | MCUTS |
| Organisation | Grassroot Soccer |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | 2 papers published - detail in publications section of researchfish submission Multi-disciplinary: epidemiology, public health |
| Start Year | 2013 |
| Description | MDR-TB infection control |
| Organisation | Queen Margaret University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | co-design of study and analysis |
| Collaborator Contribution | co-design, coordination, ethnographic work, policy review, laboratory work, health economics |
| Impact | Multi-disciplinary: Epidemiology, public health, health economics, modelling, anthropology, statistics |
| Start Year | 2017 |
| Description | MDR-TB infection control |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | co-design of study and analysis |
| Collaborator Contribution | co-design, coordination, ethnographic work, policy review, laboratory work, health economics |
| Impact | Multi-disciplinary: Epidemiology, public health, health economics, modelling, anthropology, statistics |
| Start Year | 2017 |
| Description | MDR-TB infection control |
| Organisation | University of Cape Town |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | co-design of study and analysis |
| Collaborator Contribution | co-design, coordination, ethnographic work, policy review, laboratory work, health economics |
| Impact | Multi-disciplinary: Epidemiology, public health, health economics, modelling, anthropology, statistics |
| Start Year | 2017 |
| Description | MDR-TB infection control |
| Organisation | University of KwaZulu-Natal |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | co-design of study and analysis |
| Collaborator Contribution | co-design, coordination, ethnographic work, policy review, laboratory work, health economics |
| Impact | Multi-disciplinary: Epidemiology, public health, health economics, modelling, anthropology, statistics |
| Start Year | 2017 |
| Description | MENISCUS |
| Organisation | MRC/UVRI Uganda Research Unit on AIDS |
| Country | Uganda |
| Sector | Public |
| PI Contribution | Leadership, design and analysis |
| Collaborator Contribution | Study co-ordination |
| Impact | Outcome: Funding of JGHT trials development grant Multi-disciplinary: epidemiology, social science |
| Start Year | 2015 |
| Description | MENISCUS2 |
| Organisation | MRC/UVRI Uganda Research Unit on AIDS |
| Country | Uganda |
| Sector | Public |
| PI Contribution | Leadership, design and analysis |
| Collaborator Contribution | Study co-ordination |
| Impact | Multi-disciplinary: epidemiology, social science |
| Start Year | 2017 |
| Description | MTV Shuga Evaluation |
| Organisation | Africa Health Research Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | co-investigator; study design and analysis |
| Collaborator Contribution | Design and running of evaluation |
| Impact | No outputs yet. Disciplines include epidemiology, public health, statistics, qualitative research |
| Start Year | 2017 |
| Description | MTV Shuga Evaluation |
| Organisation | Epicentre |
| Country | United States |
| Sector | Private |
| PI Contribution | co-investigator; study design and analysis |
| Collaborator Contribution | Design and running of evaluation |
| Impact | No outputs yet. Disciplines include epidemiology, public health, statistics, qualitative research |
| Start Year | 2017 |
| Description | MTV Shuga Evaluation |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | co-investigator; study design and analysis |
| Collaborator Contribution | Design and running of evaluation |
| Impact | No outputs yet. Disciplines include epidemiology, public health, statistics, qualitative research |
| Start Year | 2017 |
| Description | Management of child malnutrition in India |
| Organisation | Médecins Sans Frontières (MSF) |
| Country | France |
| Sector | Charity/Non Profit |
| PI Contribution | study design & analysis |
| Collaborator Contribution | study design & analysis, field visits |
| Impact | None yet. Multi-disciplinary: clinical trials, epidemiology, public health, statistics |
| Start Year | 2017 |
| Description | Monitoring and Evaluation of implementation of interventions for VL in Africa and Asia |
| Organisation | Drugs for Neglected Diseases initiative (DNDi) |
| Country | Switzerland |
| Sector | Charity/Non Profit |
| PI Contribution | Contributing to design and analysis of surveys |
| Collaborator Contribution | Project management, intellectual input |
| Impact | Multi disciplinary - Epidemiology, public health, statistics |
| Start Year | 2014 |
| Description | Monitoring and Evaluation of implementation of interventions for VL in Africa and Asia |
| Organisation | Mott Macdonald UK Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Contributing to design and analysis of surveys |
| Collaborator Contribution | Project management, intellectual input |
| Impact | Multi disciplinary - Epidemiology, public health, statistics |
| Start Year | 2014 |
| Description | Monitoring and Evaluation of implementation of interventions for VL in Africa and Asia |
| Organisation | Médecins Sans Frontières (MSF) |
| Country | France |
| Sector | Charity/Non Profit |
| PI Contribution | Contributing to design and analysis of surveys |
| Collaborator Contribution | Project management, intellectual input |
| Impact | Multi disciplinary - Epidemiology, public health, statistics |
| Start Year | 2014 |
| Description | Namibia Malaria Elimination Partnership (NAMEP) |
| Organisation | Clinton Health Access Initiative |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance; support to namtional Malaria Control programme |
| Impact | "Trial Protocol; Smith, J. L., Auala, J., Haindongo, E., Uusiku, P., Gosling, R., Kleinschmidt, I., Mumbengegwi, D., Sturrock, H. J. W. (2017). Malaria risk in young male travellers but local transmission persists: a case-control study in low transmission Namibia. Malaria Journal, 16, 70. http://doi.org/10.1186/s12936-017-1719-x" Multi-disciplinary: Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | Namibia Malaria Elimination Partnership (NAMEP) |
| Organisation | National Vector-borne Diseases Control Programme (NVDCP) |
| Country | Namibia |
| Sector | Public |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance; support to namtional Malaria Control programme |
| Impact | "Trial Protocol; Smith, J. L., Auala, J., Haindongo, E., Uusiku, P., Gosling, R., Kleinschmidt, I., Mumbengegwi, D., Sturrock, H. J. W. (2017). Malaria risk in young male travellers but local transmission persists: a case-control study in low transmission Namibia. Malaria Journal, 16, 70. http://doi.org/10.1186/s12936-017-1719-x" Multi-disciplinary: Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | Namibia Malaria Elimination Partnership (NAMEP) |
| Organisation | University of California, San Francisco |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance; support to namtional Malaria Control programme |
| Impact | "Trial Protocol; Smith, J. L., Auala, J., Haindongo, E., Uusiku, P., Gosling, R., Kleinschmidt, I., Mumbengegwi, D., Sturrock, H. J. W. (2017). Malaria risk in young male travellers but local transmission persists: a case-control study in low transmission Namibia. Malaria Journal, 16, 70. http://doi.org/10.1186/s12936-017-1719-x" Multi-disciplinary: Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | Namibia Malaria Elimination Partnership (NAMEP) |
| Organisation | University of Namibia |
| Country | Namibia |
| Sector | Academic/University |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance; support to namtional Malaria Control programme |
| Impact | "Trial Protocol; Smith, J. L., Auala, J., Haindongo, E., Uusiku, P., Gosling, R., Kleinschmidt, I., Mumbengegwi, D., Sturrock, H. J. W. (2017). Malaria risk in young male travellers but local transmission persists: a case-control study in low transmission Namibia. Malaria Journal, 16, 70. http://doi.org/10.1186/s12936-017-1719-x" Multi-disciplinary: Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | Namibia Malaria Elimination Partnership (NAMEP) |
| Organisation | University of the Witwatersrand |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance; support to namtional Malaria Control programme |
| Impact | "Trial Protocol; Smith, J. L., Auala, J., Haindongo, E., Uusiku, P., Gosling, R., Kleinschmidt, I., Mumbengegwi, D., Sturrock, H. J. W. (2017). Malaria risk in young male travellers but local transmission persists: a case-control study in low transmission Namibia. Malaria Journal, 16, 70. http://doi.org/10.1186/s12936-017-1719-x" Multi-disciplinary: Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | New nets project |
| Organisation | Entomological Research Centre of Cotonou (CREC) |
| Country | Benin |
| Sector | Academic/University |
| PI Contribution | sample size, study design, statistical analysis, data management |
| Collaborator Contribution | field activities |
| Impact | Multi-disciplinary: epidemiology, vector control, entomology |
| Start Year | 2018 |
| Description | Newton Household Screening - Aurum (Asibamisane) |
| Organisation | Aurum Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Study design and analysis |
| Collaborator Contribution | Study design and co-ordination |
| Impact | Multi-disciplinary: public health, health economics, statistics, qualitative |
| Start Year | 2016 |
| Description | OFLOTUB |
| Organisation | Ignace Deen Hospital |
| Country | Guinea |
| Sector | Hospitals |
| PI Contribution | Contributed to trial design, conduct of trial, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Results presented at the Union TB conference in Paris, 2013. Paper published on trial design (Trials, 2012) and main trial results (NEJM, 2014). |
| Description | OFLOTUB |
| Organisation | Institute of Development Research (IRD) |
| Country | France |
| Sector | Academic/University |
| PI Contribution | Contributed to trial design, conduct of trial, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Results presented at the Union TB conference in Paris, 2013. Paper published on trial design (Trials, 2012) and main trial results (NEJM, 2014). |
| Description | OFLOTUB |
| Organisation | Institute of Tropical Medicine Antwerp |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | Contributed to trial design, conduct of trial, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Results presented at the Union TB conference in Paris, 2013. Paper published on trial design (Trials, 2012) and main trial results (NEJM, 2014). |
| Description | OFLOTUB |
| Organisation | Medical Research Council of South Africa (MRC) |
| Country | South Africa |
| Sector | Public |
| PI Contribution | Contributed to trial design, conduct of trial, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Results presented at the Union TB conference in Paris, 2013. Paper published on trial design (Trials, 2012) and main trial results (NEJM, 2014). |
| Description | OFLOTUB |
| Organisation | National Hospital of Pneumo-Phtisiology |
| Country | Benin |
| Sector | Hospitals |
| PI Contribution | Contributed to trial design, conduct of trial, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Results presented at the Union TB conference in Paris, 2013. Paper published on trial design (Trials, 2012) and main trial results (NEJM, 2014). |
| Description | OFLOTUB |
| Organisation | Programme National de Lutte contre la Tuberculose |
| Country | Senegal |
| Sector | Public |
| PI Contribution | Contributed to trial design, conduct of trial, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Results presented at the Union TB conference in Paris, 2013. Paper published on trial design (Trials, 2012) and main trial results (NEJM, 2014). |
| Description | OFLOTUB |
| Organisation | University Hospitals in Paris |
| Country | France |
| Sector | Academic/University |
| PI Contribution | Contributed to trial design, conduct of trial, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Results presented at the Union TB conference in Paris, 2013. Paper published on trial design (Trials, 2012) and main trial results (NEJM, 2014). |
| Description | OFLOTUB |
| Organisation | World Health Organization (WHO) |
| Department | Tropical Disease Research (TDR) |
| Country | Switzerland |
| Sector | Public |
| PI Contribution | Contributed to trial design, conduct of trial, statistical support, data analysis |
| Collaborator Contribution | Significant intellectual input and exchange of ideas |
| Impact | Results presented at the Union TB conference in Paris, 2013. Paper published on trial design (Trials, 2012) and main trial results (NEJM, 2014). |
| Description | PANGEA |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We will be contributing specimens (from PopART trial) to an international collaboration using sequencing and phylogenetic analysis to better understand the transmission dynamics of HIV. |
| Collaborator Contribution | Co-ordination; organisation of sequencing pipeline; workshops; financial management. |
| Impact | Multi-disciplinary: Epidemiology, public health |
| Start Year | 2013 |
| Description | POPVAC trials |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/UVRI and LSHTM Research Unit Uganda |
| Country | Uganda |
| Sector | Academic/University |
| PI Contribution | study design and set up, study anlaysis |
| Collaborator Contribution | field activities, trial management, study design |
| Impact | Multi-disciplinary: statistics, clinical trials, immunology, public health |
| Start Year | 2018 |
| Description | PREMIUM |
| Organisation | Sangath |
| Country | India |
| Sector | Charity/Non Profit |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | 3 papers published, detail in publications section of submission Multi-disciplinary: epidemiology, public health |
| Start Year | 2010 |
| Description | PRIDE |
| Organisation | Harvard University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Statistical support |
| Collaborator Contribution | Study design, implementation and evaluation |
| Impact | one publication, main results paper submitted. Multidisciplinary: epidemiology, psychiatry |
| Start Year | 2017 |
| Description | PROSPECT study |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | statistical advice |
| Collaborator Contribution | study design; coordination; field activities; analysis |
| Impact | None yet. Multidisciplinary: epidemiology, public health, statistics, clinical trials |
| Start Year | 2017 |
| Description | PROSPECT study |
| Organisation | Wellcome Trust |
| Department | Malawi-Liverpool Wellcome Trust Clinical Research Programme |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | statistical advice |
| Collaborator Contribution | study design; coordination; field activities; analysis |
| Impact | None yet. Multidisciplinary: epidemiology, public health, statistics, clinical trials |
| Start Year | 2017 |
| Description | Paediatric praziquantel |
| Organisation | Brown University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | study design; statistical advice; analysis |
| Collaborator Contribution | study design; coordination; field activities |
| Impact | None yet. Multidisciplinary: epidemiology, public health, statistics, clinical trials |
| Start Year | 2017 |
| Description | Paediatric praziquantel |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/UVRI and LSHTM Research Unit Uganda |
| Country | Uganda |
| Sector | Academic/University |
| PI Contribution | study design; statistical advice; analysis |
| Collaborator Contribution | study design; coordination; field activities |
| Impact | None yet. Multidisciplinary: epidemiology, public health, statistics, clinical trials |
| Start Year | 2017 |
| Description | Paediatric praziquantel |
| Organisation | Ministry of Health, Uganda |
| Country | Uganda |
| Sector | Public |
| PI Contribution | study design; statistical advice; analysis |
| Collaborator Contribution | study design; coordination; field activities |
| Impact | None yet. Multidisciplinary: epidemiology, public health, statistics, clinical trials |
| Start Year | 2017 |
| Description | Pangea2 |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We will be contributing specimens (from PopART trial) to an international collaboration using sequencing and phylogenetic analysis to better understand the transmission dynamics of HIV. |
| Collaborator Contribution | Co-ordination; organisation of sequencing pipeline; workshops; financial management. |
| Impact | None yet. Multidisciplinary: Epidemiology, public health, molecular epidemiology,virology |
| Start Year | 2018 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Bill and Melinda Gates Foundation |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Country | United States |
| Sector | Public |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Georgia Institute of Technology |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Ghana Health Service |
| Country | Ghana |
| Sector | Public |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Health Protection and Research Organisation (HPRO) |
| Country | Afghanistan |
| Sector | Public |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | HealthNet |
| Country | Afghanistan |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Ifakara Health Institute |
| Country | Tanzania, United Republic of |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Karolinska Institute |
| Department | Department of Public Health Sciences |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Kilimanjaro Christian Medical Centre (KCMS) |
| Country | Tanzania, United Republic of |
| Sector | Hospitals |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Kintampo Health Research Centre |
| Country | Ghana |
| Sector | Hospitals |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Liverpool School of Tropical Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Makerere University |
| Country | Uganda |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Merlin, Afghanistan |
| Country | Afghanistan |
| Sector | Private |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Ministry of Health, Uganda |
| Country | Uganda |
| Sector | Public |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | National Institute for Medical Research, Tanzania |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | National Malaria Control Programme, Cambodia |
| Country | Cambodia |
| Sector | Public |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | National Malaria Control Programme, Tanzania |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | University of California, San Francisco |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | University of Cape Town |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | University of Copenhagen |
| Country | Denmark |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | University of Malawi |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | University of Nigeria |
| Country | Nigeria |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | University of Yaoundé |
| Country | Cameroon |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: Consortium for research on delivery of artemisinin combination therapy (ACT) |
| Organisation | Zanzibar Malaria Control Program |
| Country | Tanzania, United Republic of |
| Sector | Academic/University |
| PI Contribution | Statistical advice, study design |
| Collaborator Contribution | Intellectual input and mutual exchange of ideas; financial contribution; access to data and facilities |
| Impact | Progress in research on delivery of artemisinin combination therapy; uptake of rapid diagnostic tests (RDTs) and health facility training with associated effects on diagnostic practices and patient outcomes; secondary analysis of trial data and preparation of cross-cutting papers; modelling of long-acting ACT for malaria case-management |
| Start Year | 2008 |
| Description | Partnership: TB preventive therapy and case finding with the consortium to respond effectively to the AIDS and TB epidemics (CREATE) |
| Organisation | Johns Hopkins University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | TEG has contributed to the design of two clinical trials: Zamstar and Thibela TB. We have also developed the trial protocols and provided statistical support and led on data analysis. |
| Collaborator Contribution | Collaborative involvement in statistical analysis of cluster randomised trials and data management of large field-based studies |
| Impact | Both trials have been completed successfully. Zamstar results presented at Union World Conference on Lung Health (2011) and CROI (2012). Thibela results presented at CROI (2012) and the South African TB Conference (2012). Trial results have been published - Zamstar in Lancet (2013) and Thibela in NEJM (2014). Several publications are in progress and we intend to apply the learning from both trials to future trial design. |
| Start Year | 2006 |
| Description | PopART modelling and phylogenetics |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | study design, coordination, publications |
| Collaborator Contribution | mathematical modelling, phylogenetics/sequencing |
| Impact | Poster at CROI conference Multi-disciplinary: modelling, sequencing, epidemiology Information sheet on their Best Practices Compendium of evidence-based interventions for HIV prevention |
| Start Year | 2018 |
| Description | PrEP demonstration projectc |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | co-design of study and analysis; coordination of project at the Africa Centre site |
| Collaborator Contribution | co-design, coordination of project at 2 other sites (Cape Town & Soweto) |
| Impact | Multi-disciplinary: epidemiology, public health, health economics, social science, statistics |
| Start Year | 2016 |
| Description | PrEP demonstration projectc |
| Organisation | University of Cape Town |
| Department | Desmond Tutu HIV Centre |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | co-design of study and analysis; coordination of project at the Africa Centre site |
| Collaborator Contribution | co-design, coordination of project at 2 other sites (Cape Town & Soweto) |
| Impact | Multi-disciplinary: epidemiology, public health, health economics, social science, statistics |
| Start Year | 2016 |
| Description | PrEP demonstration projectc |
| Organisation | University of Cape Town |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | co-design of study and analysis; coordination of project at the Africa Centre site |
| Collaborator Contribution | co-design, coordination of project at 2 other sites (Cape Town & Soweto) |
| Impact | Multi-disciplinary: epidemiology, public health, health economics, social science, statistics |
| Start Year | 2016 |
| Description | PrEP demonstration projectc |
| Organisation | University of the Witwatersrand |
| Department | Perinatal HIV Research Unit |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | co-design of study and analysis; coordination of project at the Africa Centre site |
| Collaborator Contribution | co-design, coordination of project at 2 other sites (Cape Town & Soweto) |
| Impact | Multi-disciplinary: epidemiology, public health, health economics, social science, statistics |
| Start Year | 2016 |
| Description | Preparing for clinical trials of interventions to improve the reproductive health of adolescent girls in sub-Saharan Africa |
| Organisation | Institute of Tropical Medicine Antwerp |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | study design, statistical analysis, co-investigators |
| Collaborator Contribution | priniciple investiagor; sample testing; significant intellectual input and exchange of ideas |
| Impact | Results pending; analyses currently underway |
| Start Year | 2012 |
| Description | Preparing for clinical trials of interventions to improve the reproductive health of adolescent girls in sub-Saharan Africa |
| Organisation | National Institute for Medical Research, Tanzania |
| Department | Mwanza Intervention Trials Unit (MITU) |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | study design, statistical analysis, co-investigators |
| Collaborator Contribution | priniciple investiagor; sample testing; significant intellectual input and exchange of ideas |
| Impact | Results pending; analyses currently underway |
| Start Year | 2012 |
| Description | Preparing for clinical trials of interventions to improve the reproductive health of adolescent girls in sub-Saharan Africa |
| Organisation | National Institute for Medical Research, Tanzania |
| Department | NIMR Mbeya Research Centre |
| Country | Tanzania, United Republic of |
| Sector | Academic/University |
| PI Contribution | study design, statistical analysis, co-investigators |
| Collaborator Contribution | priniciple investiagor; sample testing; significant intellectual input and exchange of ideas |
| Impact | Results pending; analyses currently underway |
| Start Year | 2012 |
| Description | REEHAD study, The Role of Environmental Enteropathy on HIV-Associated Diabetes |
| Organisation | National Institute for Medical Research, Tanzania |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | sample size, study design, statistical analysis, data management |
| Collaborator Contribution | field activities |
| Impact | Multi-disciplinary: Nutrition, epidemiology, gastroenterology |
| Start Year | 2019 |
| Description | RIFASHORT trial |
| Organisation | St George's University of London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | sample size, study design, statistical analysis, data management |
| Collaborator Contribution | trial design and coordination, field activities |
| Impact | Multi-disciplinary: epidemiology, public health, statistics, clinical trials |
| Start Year | 2016 |
| Description | RKSK evaluation |
| Organisation | Public Health Foundation of India |
| Country | India |
| Sector | Public |
| PI Contribution | Co-design of evaluation of governmental adolescent health programme ("RKSK") and will do the analysis |
| Collaborator Contribution | Co-design and running of evaluation |
| Impact | Outcome: successful grant application to the MRC Multi-disciplinary: Epidemiology, public health, statistics |
| Start Year | 2016 |
| Description | RTS,S-SMC trial |
| Organisation | National Center for Scientific and Technological Research (CNRST) |
| Department | Institute of Research in Health Sciences |
| Country | Burkina Faso |
| Sector | Public |
| PI Contribution | Study design, analysis |
| Collaborator Contribution | Clinical, field, lab studies |
| Impact | None yet, (main trial paper later in 2020) Multidisciplinary: epidemiology, statistics, clinical trials |
| Start Year | 2017 |
| Description | RTS,S-SMC trial |
| Organisation | University of Bamako |
| Department | Malaria Research and Training Centre (MRTC) Bamako |
| Country | Mali |
| Sector | Academic/University |
| PI Contribution | Study design, analysis |
| Collaborator Contribution | Clinical, field, lab studies |
| Impact | None yet, (main trial paper later in 2020) Multidisciplinary: epidemiology, statistics, clinical trials |
| Start Year | 2017 |
| Description | RifT Study |
| Organisation | Makerere University |
| Department | Infectious Diseases Institute |
| Country | Uganda |
| Sector | Academic/University |
| PI Contribution | Sample size and statistical advice |
| Collaborator Contribution | study design and setup, coordination, protocol writing, ethics applications |
| Impact | No outputs yet. Disciplines include clinical trials, epidemiology, public health, statistics |
| Start Year | 2017 |
| Description | RifT Study |
| Organisation | Radboud University Nijmegen |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Sample size and statistical advice |
| Collaborator Contribution | study design and setup, coordination, protocol writing, ethics applications |
| Impact | No outputs yet. Disciplines include clinical trials, epidemiology, public health, statistics |
| Start Year | 2017 |
| Description | SEHER |
| Organisation | Sangath |
| Country | India |
| Sector | Charity/Non Profit |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2013 |
| Description | STAMP |
| Organisation | Harvard University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Chief-Investigator, Study design and analysis |
| Collaborator Contribution | Study design, co-ordination, economic modelling, trial recruitment |
| Impact | PMID: 27007773; 27659507 ; 27638038; 26266773; 31781758; 30951533; 30683239; 30032978 Multi-disciplinary: public health, health economics, statistics |
| Start Year | 2015 |
| Description | STAMP |
| Organisation | University of Cape Town |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Chief-Investigator, Study design and analysis |
| Collaborator Contribution | Study design, co-ordination, economic modelling, trial recruitment |
| Impact | PMID: 27007773; 27659507 ; 27638038; 26266773; 31781758; 30951533; 30683239; 30032978 Multi-disciplinary: public health, health economics, statistics |
| Start Year | 2015 |
| Description | STAMP |
| Organisation | Wellcome Trust |
| Department | Malawi-Liverpool Wellcome Trust Clinical Research Programme |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | Chief-Investigator, Study design and analysis |
| Collaborator Contribution | Study design, co-ordination, economic modelling, trial recruitment |
| Impact | PMID: 27007773; 27659507 ; 27638038; 26266773; 31781758; 30951533; 30683239; 30032978 Multi-disciplinary: public health, health economics, statistics |
| Start Year | 2015 |
| Description | STAR Malawi - secondary distribution of HIVST in ANC |
| Organisation | Wellcome Trust |
| Department | Malawi-Liverpool Wellcome Trust Clinical Research Programme |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | Study design and statistical support |
| Collaborator Contribution | Study co-ordination |
| Impact | Multi-disciplinary: Epidemiology, economics, qualitative (most of these outputs are across more than one country) doi: 10.1136/bmjopen-2019-033435; 10.1002/jia2.25255; 10.1002/jia2.25238; 10.1097/QAD.0000000000001918; 10.1186/s12889-018-6120-3. |
| Start Year | 2018 |
| Description | STAR Zambia - Cohort study of secondary distribution and case studies of distribution models |
| Organisation | University of Zambia |
| Department | Zambart |
| Country | Zambia |
| Sector | Academic/University |
| PI Contribution | Study design and statistical support |
| Collaborator Contribution | Study coordination |
| Impact | Multi-disciplinary: Epidemiology, economics, qualitative |
| Start Year | 2018 |
| Description | STAR Zimbabwe |
| Organisation | Centre for Sexual Health and HIV AIDS Research Zimbabwe (CeSHHAR Zimbabwe) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Study design and statistical support |
| Collaborator Contribution | Study coordination |
| Impact | Multi-disciplinary: Epidemiology, economics, qualitative |
| Start Year | 2018 |
| Description | STIMA |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Country | United States |
| Sector | Public |
| PI Contribution | Protocol development and review of analysis and paper |
| Collaborator Contribution | FHI was leading the project and carried out the analysis |
| Impact | 1 paper. |
| Start Year | 2014 |
| Description | STIMA |
| Organisation | Family Health International |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Protocol development and review of analysis and paper |
| Collaborator Contribution | FHI was leading the project and carried out the analysis |
| Impact | 1 paper. |
| Start Year | 2014 |
| Description | STIMA |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | Protocol development and review of analysis and paper |
| Collaborator Contribution | FHI was leading the project and carried out the analysis |
| Impact | 1 paper. |
| Start Year | 2014 |
| Description | Scrub typhus India |
| Organisation | Christian Medical College, Vellore |
| Country | India |
| Sector | Academic/University |
| PI Contribution | Study design and analysis |
| Collaborator Contribution | As previous, plus field and lab work. |
| Impact | Multi-disciplinary: epidemiology, clinical science, entomology, statistics, diagnostic assays. |
| Start Year | 2018 |
| Description | Secondment to Nagasaki University |
| Organisation | Nagasaki University |
| Country | Japan |
| Sector | Academic/University |
| PI Contribution | Secondment to Nagasaki University (50%) to support research including TB & NCDs in the Philippines, epidemics, malaria. study design & analysis |
| Collaborator Contribution | study design & analysis, field visits |
| Impact | two papers submitted, two in preparation Multi-disciplinary: epidemiology, public health, statistics |
| Start Year | 2018 |
| Description | Severe corneal infections |
| Organisation | Kilimanjaro Christian Medical Centre (KCMS) |
| Country | Tanzania, United Republic of |
| Sector | Hospitals |
| PI Contribution | sample size, study design, statistical analysis, data management |
| Collaborator Contribution | Study coordination |
| Impact | Multidisciplinary: epidemiology, public health, statistics |
| Start Year | 2018 |
| Description | Severe corneal infections |
| Organisation | Mbarara National Referral Hospital |
| Country | Uganda |
| Sector | Hospitals |
| PI Contribution | sample size, study design, statistical analysis, data management |
| Collaborator Contribution | Study coordination |
| Impact | Multidisciplinary: epidemiology, public health, statistics |
| Start Year | 2018 |
| Description | Severe corneal infections |
| Organisation | Sagarmatha Choudhary Eye Hospital |
| Country | Nepal |
| Sector | Hospitals |
| PI Contribution | sample size, study design, statistical analysis, data management |
| Collaborator Contribution | Study coordination |
| Impact | Multidisciplinary: epidemiology, public health, statistics |
| Start Year | 2018 |
| Description | Spatial intelligence system for precision larviciding |
| Organisation | Aberystwyth University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | sample size, study design, statistical analysis, data management |
| Collaborator Contribution | trial design and coordination, field activities |
| Impact | Multi-disciplinary: epidemiology, vector control, geography, spatial |
| Start Year | 2018 |
| Description | Statistical support: Mwanza MITU/NIMR |
| Organisation | National Institute for Medical Research, Tanzania |
| Department | Mwanza Intervention Trials Unit (MITU) |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | Epidemiological and statistical input to field studies; design of new studies and preparation of funding applications; capacity building |
| Collaborator Contribution | Collaborative involvement in and field sites for studies of the epidemiology and control of HIV and related infections |
| Impact | HIV microbicide and vaccine feasibility studies, and studies of HPV vaccination and epidemiology successfully completed. Studies of chronic diseases and structural interventions to reduce gender violence ongoing |
| Start Year | 2006 |
| Description | Stepped wedge trial analysis |
| Organisation | Monash University |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Project leaders, design of simulation study, conduct analysis, writing paper |
| Collaborator Contribution | Design of simulation study, expertise in methods, contributing to paper writing |
| Impact | Oral presentation at the International Conference on Stepped Wedge Trial Design, UK, and at the Meeting for Current Developments in Cluster Randomised Trials and Stepped Wedge Designs, UK. Multi-disciplinary: Statistics, Clinical Trials |
| Start Year | 2018 |
| Description | Stepped wedge trial analysis |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Project leaders, design of simulation study, conduct analysis, writing paper |
| Collaborator Contribution | Design of simulation study, expertise in methods, contributing to paper writing |
| Impact | Oral presentation at the International Conference on Stepped Wedge Trial Design, UK, and at the Meeting for Current Developments in Cluster Randomised Trials and Stepped Wedge Designs, UK. Multi-disciplinary: Statistics, Clinical Trials |
| Start Year | 2018 |
| Description | Stronger SAFE |
| Organisation | Fred Hollows Foundation |
| Country | Australia |
| Sector | Charity/Non Profit |
| PI Contribution | Study design, statistical advice, analysis |
| Collaborator Contribution | study design; coordination; field work; economic modelling; |
| Impact | No outputs yet. Disciplines include epidemiology, public health, statistics, qualitative research |
| Start Year | 2017 |
| Description | Stronger SAFE |
| Organisation | The Wellcome Trust Sanger Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Study design, statistical advice, analysis |
| Collaborator Contribution | study design; coordination; field work; economic modelling; |
| Impact | No outputs yet. Disciplines include epidemiology, public health, statistics, qualitative research |
| Start Year | 2017 |
| Description | TB & NCDs in the Philippines |
| Organisation | Nagasaki University |
| Country | Japan |
| Sector | Academic/University |
| PI Contribution | study design & analysis |
| Collaborator Contribution | study design & analysis, field visits |
| Impact | none yet. Multidisciplinary: epidemiology, public health, statistics |
| Start Year | 2016 |
| Description | TB China: CRT of medication monitor in TB case management |
| Organisation | Bill and Melinda Gates Foundation |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Expertise in TB epidemiology, field studies |
| Impact | Design of current cluster-randomized trial including economic costing of intervention; ongoing analysis of previous trial. Disciplines involved - Epidemiology, public health, health economics |
| Start Year | 2010 |
| Description | TB China: CRT of medication monitor in TB case management |
| Organisation | Chinese Center for Disease Control and Prevention (China CDC) |
| Country | China |
| Sector | Public |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Expertise in TB epidemiology, field studies |
| Impact | Design of current cluster-randomized trial including economic costing of intervention; ongoing analysis of previous trial. Disciplines involved - Epidemiology, public health, health economics |
| Start Year | 2010 |
| Description | TB China: CRT of medication monitor in TB case management |
| Organisation | Government of China |
| Department | Ministry of Health of the People's Republic of China |
| Country | China |
| Sector | Public |
| PI Contribution | Contributed to trial design, statistical support, data analysis |
| Collaborator Contribution | Expertise in TB epidemiology, field studies |
| Impact | Design of current cluster-randomized trial including economic costing of intervention; ongoing analysis of previous trial. Disciplines involved - Epidemiology, public health, health economics |
| Start Year | 2010 |
| Description | TB adherence |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration with Dr Helen Stagg on measuring adherence to TB treatment |
| Collaborator Contribution | Collaboration with Prof Katherine Fielding on measuring adherence to TB treatment |
| Impact | Multi-disciplinary: epidemiology, public health, statistics. Paper published- doi: 10.1513/AnnalsATS.201905-394OC |
| Start Year | 2018 |
| Description | TB042 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/UVRI and LSHTM Research Unit Uganda |
| Country | Uganda |
| Sector | Academic/University |
| PI Contribution | trial statistician |
| Collaborator Contribution | trial design and coordination; field activities |
| Impact | None yet. Multidisciplinary: public health, vaccines, clinical trials |
| Start Year | 2018 |
| Description | TB042 |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | trial statistician |
| Collaborator Contribution | trial design and coordination; field activities |
| Impact | None yet. Multidisciplinary: public health, vaccines, clinical trials |
| Start Year | 2018 |
| Description | TREATS |
| Organisation | HST |
| PI Contribution | Epidemiological and statistical input to study design and analysis. Liaison between TREATS and parent PopART trial. |
| Collaborator Contribution | Expertise in TB epidemiology, diagnostics, field studies and modelling |
| Impact | None yet. Multidisciplinary: Epidemiology, public health, diagnostics, modelling |
| Start Year | 2017 |
| Description | TREATS |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Epidemiological and statistical input to study design and analysis. Liaison between TREATS and parent PopART trial. |
| Collaborator Contribution | Expertise in TB epidemiology, diagnostics, field studies and modelling |
| Impact | None yet. Multidisciplinary: Epidemiology, public health, diagnostics, modelling |
| Start Year | 2017 |
| Description | TREATS |
| Organisation | International Union Against Tuberculosis and Lung Disease (The Union) |
| Country | Global |
| Sector | Academic/University |
| PI Contribution | Epidemiological and statistical input to study design and analysis. Liaison between TREATS and parent PopART trial. |
| Collaborator Contribution | Expertise in TB epidemiology, diagnostics, field studies and modelling |
| Impact | None yet. Multidisciplinary: Epidemiology, public health, diagnostics, modelling |
| Start Year | 2017 |
| Description | TREATS |
| Organisation | Royal Netherlands Chemical Society |
| Country | Netherlands |
| Sector | Learned Society |
| PI Contribution | Epidemiological and statistical input to study design and analysis. Liaison between TREATS and parent PopART trial. |
| Collaborator Contribution | Expertise in TB epidemiology, diagnostics, field studies and modelling |
| Impact | None yet. Multidisciplinary: Epidemiology, public health, diagnostics, modelling |
| Start Year | 2017 |
| Description | TREATS |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Epidemiological and statistical input to study design and analysis. Liaison between TREATS and parent PopART trial. |
| Collaborator Contribution | Expertise in TB epidemiology, diagnostics, field studies and modelling |
| Impact | None yet. Multidisciplinary: Epidemiology, public health, diagnostics, modelling |
| Start Year | 2017 |
| Description | TREATS |
| Organisation | Zambia AIDS Related Tuberculosis |
| Country | Zambia |
| Sector | Academic/University |
| PI Contribution | Epidemiological and statistical input to study design and analysis. Liaison between TREATS and parent PopART trial. |
| Collaborator Contribution | Expertise in TB epidemiology, diagnostics, field studies and modelling |
| Impact | None yet. Multidisciplinary: Epidemiology, public health, diagnostics, modelling |
| Start Year | 2017 |
| Description | Targetted control to eliminate malaria in Senegal |
| Organisation | University Cheikh Anta Diop de Dakar |
| Country | Senegal |
| Sector | Academic/University |
| PI Contribution | Design and coordination and analysis of the cluster randomized trial |
| Collaborator Contribution | They led the coordination of field activities |
| Impact | The trial result will be available Q4 2015. This collaboration is multi-disciplinary involving epidemiology, statistics, economics, social science, clinical medicine, molecular biology, entomology, public health, parasitology. |
| Start Year | 2011 |
| Description | Trial to evaluate targeted parasite elimination (TPE) as a strategy to interrupt malaria transmission |
| Organisation | Clinton Health Access Initiative |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance |
| Impact | Trial protocol. Multi disciplinary - Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | Trial to evaluate targeted parasite elimination (TPE) as a strategy to interrupt malaria transmission |
| Organisation | National Vector-borne Diseases Control Programme (NVDCP) |
| Country | Namibia |
| Sector | Public |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance |
| Impact | Trial protocol. Multi disciplinary - Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | Trial to evaluate targeted parasite elimination (TPE) as a strategy to interrupt malaria transmission |
| Organisation | University of California, San Francisco |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance |
| Impact | Trial protocol. Multi disciplinary - Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | Trial to evaluate targeted parasite elimination (TPE) as a strategy to interrupt malaria transmission |
| Organisation | University of Namibia |
| Country | Namibia |
| Sector | Academic/University |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance |
| Impact | Trial protocol. Multi disciplinary - Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | Trial to evaluate targeted parasite elimination (TPE) as a strategy to interrupt malaria transmission |
| Organisation | University of the Witwatersrand |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Trial design; funding of vector control component through Wits University. |
| Collaborator Contribution | Funding of trial; logistics; trial management and governance |
| Impact | Trial protocol. Multi disciplinary - Epidemiology, Disease Control, Pharmacology, Entomology. Vector Control, Statistics. Modelling, Immunology |
| Start Year | 2015 |
| Description | UT3C (Universal Testing and Treatment Trials Consortium) |
| Organisation | National Institute for Medical Research, Tanzania |
| Department | Mwanza Intervention Trials Unit (MITU) |
| Country | Tanzania, United Republic of |
| Sector | Public |
| PI Contribution | Coordination of Consortium. Chairing of Consortium calls. Partnering in joint analyses and publications between PopART and other UTT trials. |
| Collaborator Contribution | Partnering in joint analyses and publications. |
| Impact | Joint paper on UTT trial designs. Disciplines include epidemiology and public health. |
| Start Year | 2015 |
| Description | VMB S.Francis |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Principal investigator - leading the project |
| Collaborator Contribution | 16SrRNA sequencing; metabolomics; Luminex testing |
| Impact | 2 papers and more in progress.Multidisciplinary: Epidemiology and laboratory science |
| Start Year | 2013 |
| Description | VMB S.Francis |
| Organisation | The Wellcome Trust Sanger Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Principal investigator - leading the project |
| Collaborator Contribution | 16SrRNA sequencing; metabolomics; Luminex testing |
| Impact | 2 papers and more in progress.Multidisciplinary: Epidemiology and laboratory science |
| Start Year | 2013 |
| Description | Vanderbilt-collaboration |
| Organisation | Vanderbilt University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Study design |
| Collaborator Contribution | Study design |
| Impact | Discipline: Trial design |
| Start Year | 2016 |
| Description | XPEL TB |
| Organisation | University of California, San Francisco |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Study design and analysis |
| Collaborator Contribution | Study design and co-ordination |
| Impact | Multi-disciplinary: public health, health economics, statistics PMID: 31720425 |
| Start Year | 2016 |
| Description | Xenomonitoring of lymphatic filariasis in Recife, Brazil |
| Organisation | Oswaldo Cruz Foundation (Fiocruz) |
| Country | Brazil |
| Sector | Public |
| PI Contribution | Leadership (Anita Ramesh) of the project which aims to establish a xenomonitoring system |
| Collaborator Contribution | Cynthia Braga is co-PI. CPqAM personnel working on the xenomonitoring project. Lab facilities. |
| Impact | None so far this year. |
| Description | ZikAlliance |
| Organisation | Heidelberg University |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Epidemiology of ZIKV with a focus on natural history, virus detection over time and disability. |
| Collaborator Contribution | University of Sao Paolo, Brazil will carry out the field activities. Heidelberg leads the large Consortium and co-ordinate a study in pregnant women and children |
| Impact | Multi-disciplinary: Epidemiology, public health, statistics |
| Start Year | 2016 |
| Description | ZikAlliance |
| Organisation | Sao Paulo State University |
| Country | Brazil |
| Sector | Academic/University |
| PI Contribution | Epidemiology of ZIKV with a focus on natural history, virus detection over time and disability. |
| Collaborator Contribution | University of Sao Paolo, Brazil will carry out the field activities. Heidelberg leads the large Consortium and co-ordinate a study in pregnant women and children |
| Impact | Multi-disciplinary: Epidemiology, public health, statistics |
| Start Year | 2016 |
| Description | ZikaPLAN |
| Organisation | Umea University |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Coordination of focus group and related activities on use of wearable technologies for protection against mosquito vectors of Zika and other arboviruses. |
| Collaborator Contribution | Universidad del Valle will carry out the field activities. |
| Impact | Multi-disciplinary - Social sciences, entomology, public health. |
| Start Year | 2016 |
| Description | Zimbabwe study for Enhancing Testing and Improving Treatment of HIV in Children |
| Organisation | Biomedical Research and Training Institute (BRTI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical and epidemiological collaboration |
| Collaborator Contribution | Leadership and all aspects of the trial |
| Impact | Trial will finish mid 2016 |
| Start Year | 2012 |
| Description | Zvandiri |
| Organisation | Centre for Sexual Health and HIV AIDS Research Zimbabwe (CeSHHAR Zimbabwe) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2014 |
| Description | Zvandiri |
| Organisation | Viiv Healthcare |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Trial design and analysis |
| Collaborator Contribution | Trial design and co-ordination |
| Impact | Multi-disciplinary: epidemiology, public health |
| Start Year | 2014 |
| Description | evaluation of GPS data |
| Organisation | Biomedical Research and Training Institute (BRTI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Study design, GIS support |
| Collaborator Contribution | Data collection |
| Impact | Paper being written |
| Start Year | 2018 |
| Title | PopART (HPTN 071) |
| Description | Universal testing and treatment for HIV |
| Type | Therapeutic Intervention - Drug |
| Current Stage Of Development | Late clinical evaluation |
| Year Development Stage Completed | 2018 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | Promotion of HIV self-testing in Zambia |
| URL | https://www.hptn.org/research/studies/hptn071 |
| Title | slopepower |
| Description | Sample size calculator for Stata, to be used for repeated measures trials where dataset exists to enable estimation of covariance matrix |
| Type Of Technology | Software |
| Year Produced | 2018 |
| Open Source License? | Yes |
| Impact | None as yet |
| URL | https://ideas.repec.org/c/boc/bocode/s458484.html |
| Title | swpermute |
| Description | command for Stata to conduct a permutation test for stepped wedge trials |
| Type Of Technology | Software |
| Year Produced | 2017 |
| Open Source License? | Yes |
| Impact | None as yet |
| URL | https://ideas.repec.org/c/boc/bocode/s458426.html |
| Description | AIDSimpact conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | oral abstract accepted for talk on ZENITH trial of lay worker support for adolescent HIV viral suppression |
| Year(s) Of Engagement Activity | 2017 |
| Description | ASTMH - J.Bradley |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation in scientific session at ASTMH: Predicting mosquito infection rates and infection intensity from Plasmodium falciparum gametocyte density and sex ratio |
| Year(s) Of Engagement Activity | 2017 |
| Description | ASTMH: ACCESS-SMC |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation in symposium at ASTMH |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.access-smc.org |
| Description | ASTMH: The Elimination Eight |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation in scientific session at ASTMH. A multi-country initiative to accelerate elimination by reducing cross-border importation of malaria:The Elimination Eight |
| Year(s) Of Engagement Activity | 2017 |
| Description | Adolescents 360 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | International Conference on Family Planning |
| Year(s) Of Engagement Activity | 2018 |
| Description | Analysis of CRTs |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Analysis of cluster randomised trials with a small number of clusters, Oral presentation at International Society for Clinical Biostatisticians conference, Melbourne |
| Year(s) Of Engagement Activity | 2018 |
| Description | Article in Significance - RSS Magazine |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Article by Richard Hayes titled "Randomising towns to fight HIV" - describes features in the design and analysis of a key HIV prevention trial in Africa that uses cluster randomisation. |
| Year(s) Of Engagement Activity | 2018 |
| Description | BBC Future |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Vicky Simms interviewed by journalist for a story on BBC Future website about Friendship Bench |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.bbc.com/future/story/20181015-how-one-bench-and-a-team-of-grandmothers-can-beat-depressio... |
| Description | BHIVA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation about design of nested study about uptake of HPTM 071 (PopART) interventions |
| Year(s) Of Engagement Activity | 2013 |
| Description | China CRT I |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation at Harvard, USA |
| Year(s) Of Engagement Activity | 2017 |
| Description | China CRT II |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Oral presentation at Johns Hopkins University, USA |
| Year(s) Of Engagement Activity | 2017 |
| Description | Cost effectiveness of reactive targetted indoor residual spraying |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | 4th Southern Africa Malaria Research Conference |
| Year(s) Of Engagement Activity | 2018 |
| Description | DENCO |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited talk on how to clinical classification of dengue Positive feedback on insightfulness of presentation into clinical classification of dengue |
| Year(s) Of Engagement Activity | 2014 |
| URL | http://www.redaedes.org/curso/presentacion.htm |
| Description | Digital Health Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Evidence of the importance / use of satellite and other imagery in public health |
| Year(s) Of Engagement Activity | 2017 |
| Description | Expert Women - BBC |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Kalpana Sabapathy was selected to attend an Expert Women World Service day at the BBC, to engage in media training. |