Epidemiological and statistical research on health problems of low and middle-income countries: MRC Tropical Epidemiology Group (TEG)

Lead Research Organisation: London Sch of Hygiene and Trop Medicine
Department Name: Epidemiology and Population Health

Abstract

The mission of the MRC Tropical Epidemiology Group (TEG) is to help improve health in low- and middle-income countries (LMICs), by conducting research that identifies and evaluates effective interventions.

Infectious diseases, including malaria, HIV, tuberculosis (TB) and neglected tropical diseases (NTDs), remain a main focus of our research, as they are the leading causes of ill-health in Africa. In the next grant period, we will expand our research on emerging diseases, adolescent health and non-communicable diseases - particularly hypertension, diabetes and chronic obstructive pulmonary disease, which are major disease problems in LMICs. Our research focuses on conditions that are major causes of ill-health, and for which improved prevention or treatment leads directly to improved economic and social outcomes. The importance of these issues to the UK is highlighted in the 2015 Government strategy for overseas aid, on tackling global challenges in the national interest.

The scale-up of malaria control tools, primarily long-lasting insecticidal nets, and effective combination therapies, has prevented an estimated 663 million clinical malaria cases in sub-Saharan Africa since 2000, and has made malaria elimination an achievable goal in some countries. However, these gains may be threatened by insecticide resistance, drug-resistance, and resource-constraints. Within the next grant period, our focus will be on evaluating new tools, combining new and existing control strategies, and investigating sustainable and more effective deployment of these strategies.

For HIV, we focus on the goal that 90% of those living with HIV know their status, 90% of known HIV-positive individuals receive sustained ART, and 90% of individuals on ART have durable viral suppression. For example, we are leading a major trial in South Africa and Zambia to evaluate the impact of a combination prevention intervention on new cases of HIV in the community. The intervention includes household-based HIV testing and linkage-to-health services by community care providers, and immediate initiation of treatment delivered through routine healthcare services.

TEG research on TB includes studies to evaluate improved TB treatment strategies, improved diagnosis, prevention and control of drug-resistant TB, improved TB case finding and prevention, and evaluation of structural interventions (social support and monetary incentives) to control TB. For example, we are working on a trial to evaluate an improved electronic medication device for TB patients to reduce treatment failure and subsequent recurrence/retreatment in the absence of directly observed treatment.

We will continue our long-standing work on intervention strategies for the control and elimination of NTDs, and our more recent involvement in the control of outbreaks such as the Ebola and Zika virus outbreaks. We will also continue our work on the effectiveness of lay-health worker interventions to treat common mental disorders (depression and anxiety), focusing particularly on treatment of these conditions among adolescents, in whom over half of mental health disorders start.

Through the MRC Programme Grant, we leverage additional funding for research projects and support salaries for around 30 statisticians and epidemiologists, based at LSHTM. The grant is critical to enable us to recruit and retain these scientists, who have disease and methodological expertise in the design and analysis of epidemiological studies in LMICs. We collaborate with the MRC Units in The Gambia and Uganda, and over 50 other research institutes in LMICs. We will continue our initiatives to increase capacity in medical statistics in sub-Saharan Africa, for example by expanding the MRC TEG Fellowship scheme, which to date has trained 17 medical statisticians through a Masters in Medical Statistics at LSHTM, followed by a placement year. All are now working as medical statisticians in Africa.

Technical Summary

The aim of TEG is to conduct cutting-edge epidemiological studies on health problems of low- and middle-income countries (LMICs). TEG will continue to have a major focus on the epidemiology and control of infectious diseases, with increased emphasis on evaluating delivery strategies for interventions of proven effectiveness. We will expand our research on emerging infectious diseases, adolescent health, non-communicable diseases and applied epidemiological methods. We will also expand our capacity building initiatives, including the TEG Fellowship scheme to train African statisticians. These issues are critical to the UK Government strategy for overseas aid, as indicated by the £1.5 billion Global Challenges Research Fund to support challenges in LMICs.

TEG malaria research includes assessing the scale-up and combination of malaria control tools, e.g. investigating sustainable and more effective deployment of long-lasting insecticidal nets, and effective combination therapies. For HIV, we focus on community-based approaches to improving HIV testing and linkage-to-care in sub-Saharan Africa, and interventions for key populations in high-incidence settings. Our TB research includes studies to evaluate improved TB treatment strategies, improved diagnosis, prevention and control of drug-resistant TB, improved case finding and prevention, and structural interventions. We will continue research on the control and elimination of NTDs, including the Ebola and Zika virus outbreaks. Finally, we conduct applied methodological work to advance the design and analysis of epidemiological studies in LMICs.

Through the Programme Grant, we will continue to leverage funding to recruit and retain a critical mass of scientists who have expertise in design and analysis of epidemiological studies in LMICs, and relevant disease-specific expertise. We collaborate closely with the African MRC Units and many other institutes in LMICs, with whom we published 700 papers in the past 5 year

Planned Impact

Beneficiaries of our research include i) populations in low- and middle-income countries (LMICs) affected by the diseases which we research, ii) local and national stakeholders; iii) national and international policy makers; iv) scientists within TEG; v) our collaborators in LMICs; and vi) the wider academic community of global health researchers.

i) The diseases we focus on are malaria, HIV, TB, emerging and neglected diseases - including mental health, eye health and non-communicable diseases. Each of these disproportionately affect the poorest in resource-poor countries, and those marginalised from society. These diseases also have a substantial impact on national socio-economic development. By reducing the rates of important causes of ill health, we have the potential to alleviate poverty as well as improving life expectancy. Many of the studies we undertake involve community-based interventions focused on overcoming barriers to health service access and to minimize stigma and discrimination. This is a common issue for many of the diseases we work on, and particularly for HIV and mental health, and among some of the key populations that we focus on, including adolescents and high-risk groups.

ii) We engage with local and national stakeholders, as described in the Pathways to Impact statement, and they benefit directly, for example, from our studies to evaluate optimal strategies for delivery of interventions of known effectiveness (for example on integrating HIV and non-communicable disease treatment and care); or to improve efficiency or cost of interventions (for example the first trial of reduced dose human papillomavirus (HPV) vaccine in Tanzania, or the planned trial of fractional dose pneumococcal vaccine in Kenya).

iii) We are able to ensure that results from our research and other important studies help to inform new policies and guidelines, through our role on national and international advisory committees, including as Chair of the WHO Joint Technical Expert Group on Malaria Vaccines in Pivotal Phase 3 Trials & Beyond; and members of the UNAIDS Scientific Expert Panel, the scientific advisory committees of EDCTP and CEPI (Coalition for Epidemic Preparedness, Innovations), the WHO Technical Advisory Committee on Safe Male Circumcision, the WHO Evidence Review Group on Malaria in Pregnancy, the WHO Global Malaria Programme, Surveillance Monitoring and Evaluation Technical Advisory Group, and WHO Expert Working Groups on Lassa fever, Nipah virus and MERS Co-V vaccine Target Product Profiles.

iv) The Programme Grant enables us to sustain a strong critical mass of experienced statistical epidemiologists and to provide an actively supportive academic environment and mentorship for all our staff. We regularly review and encourage career development, support the development of Fellowship and research grant applications, and provide funds for training courses and conference attendance.

v) Our collaborators benefit directly from our research (see Letters of Support), as the Programme Grant enables us to provide consistent and continuous, disease-specific, statistical and epidemiological expertise that is in short supply in global health research. This leads to high-quality scientific outputs and new grant applications, which lead to population health benefits. We also have an impact on the careers of the MSc, PhD and post-doctoral students who we teach, supervise and mentor, both at LSHTM, through our Fellowship scheme and collaborative links, as described in the Case for Support and Academic Beneficiaries sections.

vi) We produce around 120 papers annually, and disseminate findings at international conferences in order to benefit to the wider academic community working on global health. This includes clinical epidemiologists, social scientists and laboratory scientists. In March 2021 we plan to hold a two-day symposium to increase the impact and reach of our research findings.

Organisations

Publications

10 25 50
publication icon
Baisley KJ (2020) HPV prevalence around the time of sexual debut in adolescent girls in Tanzania. in Sexually transmitted infections

publication icon
Bottomley C (2019) Analysing Interrupted Time Series with a Control in Epidemiologic Methods

publication icon
Bradley J (2019) Transmission-blocking Effects of Primaquine and Methylene Blue Suggest Plasmodium falciparum Gametocyte Sterilization Rather Than Effects on Sex Ratio. in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

 
Title STAMP film 
Description An 8 minute film describing the STAMP trial. Clinical trial coordinators and research staff recruiting and following-up patients and laboratory staff, and the international trial coordinator were interviewed. 
Type Of Art Film/Video/Animation 
Year Produced 2018 
Impact Film shown at the Steve Lawn Memorial lecture, March 2018. Over 200 views https://www.youtube.com/watch?v=CoP5GIfiMe8&t=1s [full version] https://www.youtube.com/watch?v=LYHEFQsE7HE&t=12s [social media version] 
URL https://www.youtube.com/watch?v=CoP5GIfiMe8&t=1s
 
Description Design of treatment trials for 2019-nCoV cases (PS, TE)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact Should identify more rapidly increases in survival and quality of life
 
Description PopART and policy for HIV testing and treatment
Geographic Reach Africa 
Policy Influence Type Citation in other policy documents
Impact Trial findings have informed design and delivery of HIV testing services in S Africa and WHO deliberations on implementation of universal testing and treatment
URL http://hivst.org/policy/zambia
 
Description Prioritisation of 2019-nCoV vaccines (PS)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact Should identify more rapidly increases in survival and quality of life
 
Description STAMP - Article in Aidsmap following publication of CID paper
Geographic Reach Africa 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL http://www.aidsmap.com/news/feb-2020/alarmingly-high-mortality-hospitalised-patients-hivtb-co-infect...
 
Description STAMP - TAG
Geographic Reach Multiple continents/international 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL http://www.treatmentactiongroup.org/content/activists-call-countries-and-donors-immediately-scale-us...
 
Guideline Title The use of lateral flow urine lipoarabinomannan assay (LF-LAM) for the diagnosis and screening of active tuberculosis in people living with HIV
Description STAMP - preparatory work to trial cited in WHO 2019 LAM policy update
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in clinical guidelines
URL https://www.who.int/tb/publications/use-of-lf-lam-tb-hiv/en/
 
Description UK Government Period Poverty Taskforce
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
URL https://www.gov.uk/government/news/period-poverty-taskforce-minister-announces-next-steps-on-menstru...
 
Description WHO Technical Consultation on Chemoprevention (MC)
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact May lead to more flexible recommendations on chemopreventive approaches allowing its use in a wider area and/or subsequent policy changes
 
Description WHO Technical Consultation on SMC (MC)
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact May lead to more flexible recommendations on SMC allowing its use in a wider area and/or subsequent policy changes
 
Description A pragmatic randomised study to optimise screening, prevention and care for tuberculosis in Malawi (PROSPeCT Study)
Amount £1,077,349 (GBP)
Funding ID 206575 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2017 
End 08/2022
 
Description Attractant Targeted Sugar Bates (ATSB) trial
Amount $6,499,963 (USD)
Organisation IVCC 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2018 
End 12/2020
 
Description Combination prevention and strategies for HIV control: In-depth analysis of data from the HPTN 071 (PopART) trial
Amount $1,198,185 (USD)
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 02/2020 
End 01/2022
 
Description Cross-sectional survey to measure additional outcomes for the HPTN 071 (PopART study) 
Amount $700,000 (USD)
Organisation International Initiative for Impact Evaluation 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2019 
End 10/2020
 
Description Crowdsourcing with adolescents in Senegal
Amount £323,754 (GBP)
Funding ID MR/S023712/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2019 
End 08/2021
 
Description Effects of metronidazole plus intermittent preventive treatment of malaria in pregnancy on birth outcomes: a randomised controlled trial in Zambia
Amount £2,545,958 (GBP)
Funding ID MR/S004998/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 11/2018 
End 10/2022
 
Description Insecticide treated eave nets and window screens for malaria control
Amount £212,405 (GBP)
Funding ID MR/T003677/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2020 
End 06/2021
 
Description Male partner-assisted contact tracing for HIV and tuberculosis in Malawi: an adaptive multi-arm multi-stage randomised trial (mPATCH-TB)
Amount £112,515 (GBP)
Funding ID MR/R019762/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 05/2018 
End 04/2020
 
Description Operations research to measure the effectiveness of a peer-led mental health intervention on virological suppression and mental health among adolescents with HIV in Zimbabwe (ALHIV Adherence - Mental Health)
Amount $40,202 (USD)
Organisation AfricAid 
Sector Charity/Non Profit
Country United States
Start 02/2019 
End 08/2020
 
Description Perceptions, knowledge and use (and mis-use) of over the counter analgesics in East and Southern Africa
Amount £20,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2019 
End 03/2020
 
Description Randomised controlled trial of cipro vs standard of care in plague
Amount £1,588,565 (GBP)
Funding ID 216273/Z/19/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2019 
End 04/2023
 
Description Spatial Intelligence System for precision larviciding
Amount $796,731 (USD)
Organisation IVCC 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2018 
End 09/2020
 
Description TB MATE
Amount $73,273 (USD)
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 06/2019 
End 11/2021
 
Description The Bioko Island Malaria Elimination Project (BIMEP)
Amount £40,203 (GBP)
Organisation Medical Care Development 
Sector Hospitals
Country United States
Start 01/2019 
End 12/2019
 
Description The epidemiology of scrub typhus and rickettisial infections in a highly endemic rural setting in South India: Population-based Cohort Study.
Amount £767,928 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2020 
End 12/2022
 
Description UK-Brazil Joint Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology (CADDE)
Amount £1,164,840 (GBP)
Funding ID MR/S019510/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 04/2019 
End 03/2022
 
Description Zvatinoda! (What we want!): Increasing demand and uptake of sexual and reproductive health services by young people in Zimbabwe
Amount £151,520 (GBP)
Funding ID MR/T003200/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2019 
End 02/2021
 
Title Developing tools for population estimation methods (CG) 
Description Developing tools for population estimation methods 
Type Of Material Improvements to research infrastructure 
Year Produced 2019 
Provided To Others? Yes  
Impact Tool available and used for estimating populations cheaply and rapidly. Used by MITU on other research projects. Also used by Lake Victoria Consortium. Method feeding into to other research around population estimation and currently in discussions with Gates Foundation for use in EPI and other vaccine work. 
 
Description CADDE (UK-Brazil Joint Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology) 
Organisation University of Birmingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Study design and analysis, training
Collaborator Contribution Genetics, public health, virology
Impact Next Generation Sequencing workshop held in Sao Paulo, December 2019. Multidisciplinary: Genetics, public health, virology
Start Year 2018
 
Description CADDE (UK-Brazil Joint Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology) 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Study design and analysis, training
Collaborator Contribution Genetics, public health, virology
Impact Next Generation Sequencing workshop held in Sao Paulo, December 2019. Multidisciplinary: Genetics, public health, virology
Start Year 2018
 
Description CADDE (UK-Brazil Joint Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology) 
Organisation University of Sao Paulo
Country Brazil 
Sector Academic/University 
PI Contribution Study design and analysis, training
Collaborator Contribution Genetics, public health, virology
Impact Next Generation Sequencing workshop held in Sao Paulo, December 2019. Multidisciplinary: Genetics, public health, virology
Start Year 2018
 
Description CHANGE 
Organisation HealthRight International
Country United States 
Sector Hospitals 
PI Contribution Study design, analysis
Collaborator Contribution Study design, implementation and evaluation
Impact Multidisciplinary: alcohol use disorders, humanitarian health, clinical trials
Start Year 2020
 
Description CHANGE 
Organisation Johns Hopkins University
Country United States 
Sector Academic/University 
PI Contribution Study design, analysis
Collaborator Contribution Study design, implementation and evaluation
Impact Multidisciplinary: alcohol use disorders, humanitarian health, clinical trials
Start Year 2020
 
Description CHANGE 
Organisation National University of Kyiv Mohyla Academy
Country Ukraine 
Sector Academic/University 
PI Contribution Study design, analysis
Collaborator Contribution Study design, implementation and evaluation
Impact Multidisciplinary: alcohol use disorders, humanitarian health, clinical trials
Start Year 2020
 
Description CHI-S (E.Webb) 
Organisation Leiden University Medical Center
Country Netherlands 
Sector Academic/University 
PI Contribution Study design, trial statistician
Collaborator Contribution Study design; coordination; field activities; lab studies
Impact None yet, papers in preparation. Multidisciplinary: epidemiology, public health, statistics, clinical trials
Start Year 2020
 
Description CHI-S (E.Webb) 
Organisation MRC/UVRI Uganda Research Unit on AIDS
Country Uganda 
Sector Public 
PI Contribution Study design, trial statistician
Collaborator Contribution Study design; coordination; field activities; lab studies
Impact None yet, papers in preparation. Multidisciplinary: epidemiology, public health, statistics, clinical trials
Start Year 2020
 
Description CHI-S (E.Webb) 
Organisation Ministry of Health, Uganda
Country Uganda 
Sector Public 
PI Contribution Study design, trial statistician
Collaborator Contribution Study design; coordination; field activities; lab studies
Impact None yet, papers in preparation. Multidisciplinary: epidemiology, public health, statistics, clinical trials
Start Year 2020
 
Description Lurkana HIV paediatric outbreak 
Organisation Aga Khan University
Country Pakistan 
Sector Academic/University 
PI Contribution study statistician
Collaborator Contribution fieldwork, study coordination, knowledge of setting, clinical input, political engagement
Impact two publications, main results paper in progress. Multidisciplinary: epidemiology, molecular epidemiology
Start Year 2019
 
Description MERS-CoV in Jordan 
Organisation Royal Veterinary College (RVC)
Country United Kingdom 
Sector Academic/University 
PI Contribution Design of study and analysis of results
Collaborator Contribution Fieldwork in, and knowledge of, Jordan and knowledge of camels and camel infections
Impact None yet, two papers in preparation. Discipline: vet epidemiology
Start Year 2016
 
Description Oleylphosphocholine for the treatment of Old World Cutaneous Leishmaniasis(TT4CL) 
Organisation St George's University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Design of study and analysis of results
Collaborator Contribution Clinical field and lab studies.
Impact None yet. Multidisciplinary: epidemiology, clinical trials, immunology
Start Year 2019
 
Description Peek 
Organisation Peekvsion
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Study design, analysis
Collaborator Contribution Technology, programme delivery
Impact Multidisciplinary: statistics, clinical trials
Start Year 2020
 
Description Plague in Madagascar 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution trial statistician
Collaborator Contribution design and coordination of the study
Impact None yet. Multidisciplinary: statistics, clinical trials
Start Year 2019
 
Description Population estimation methods for PNG 
Organisation Medicines for Malaria Venture (MMV)
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Design and analsysis of population estimation
Collaborator Contribution Fieldwork, study coordination, provision of imagery
Impact none yet. Multidisciplinary: Epidemiology, GIS, data science
Start Year 2019
 
Description Recruitment in stepped wedge trials 
Organisation François Rabelais University or University of Tours
Country France 
Sector Academic/University 
PI Contribution Statistical support
Collaborator Contribution study design and analysis
Impact None yet. Multidisciplinary: statistics, clinical trials
Start Year 2019
 
Description Risk of bias in cluster randomized trials 
Organisation University of Birmingham
Country United Kingdom 
Sector Academic/University 
PI Contribution PhD student supervision and statistical support
Collaborator Contribution Design and analysis, and supervision
Impact None yet. Multidisciplinary: statistics, clinical trials
Start Year 2019
 
Description SUCCEED 
Organisation University of Ibadan
Country Nigeria 
Sector Academic/University 
PI Contribution Study design
Collaborator Contribution Design, implementation, analysis, interpret
Impact Multidisciplinary: Disability, epidemiology, mental health, clinical trials
Start Year 2020
 
Description SUCCEED 
Organisation University of Makeni
Country Sierra Leone 
Sector Academic/University 
PI Contribution Study design
Collaborator Contribution Design, implementation, analysis, interpret
Impact Multidisciplinary: Disability, epidemiology, mental health, clinical trials
Start Year 2020
 
Description SUCCEED 
Organisation University of Malawi
Country Malawi 
Sector Academic/University 
PI Contribution Study design
Collaborator Contribution Design, implementation, analysis, interpret
Impact Multidisciplinary: Disability, epidemiology, mental health, clinical trials
Start Year 2020
 
Description Scrub typhus India 
Organisation Christian Medical College, Vellore
Country India 
Sector Academic/University 
PI Contribution Design of study and analysis of results
Collaborator Contribution Epidemiology, ecology, one health
Impact https://onlinelibrary.wiley.com/doi/abs/10.1111/tmi.13322 Multidisciplinary: epidemiology, clinical science, entomology, statistics, diagnostic assays
Start Year 2018
 
Description Social and behavioral norms related to social protection 
Organisation Ipsos MORI
Country United Kingdom 
Sector Private 
PI Contribution Statistical support for sample design and analysis
Collaborator Contribution Ipsos coordinating data collection ; UNICEF funding
Impact Surveys from 7 countries measuring social norms, publications. Multi-disciplinary: epidemiology, public health, qualitative/anthropology
Start Year 2020
 
Description Social and behavioral norms related to social protection 
Organisation UNICEF
Country United States 
Sector Public 
PI Contribution Statistical support for sample design and analysis
Collaborator Contribution Ipsos coordinating data collection ; UNICEF funding
Impact Surveys from 7 countries measuring social norms, publications. Multi-disciplinary: epidemiology, public health, qualitative/anthropology
Start Year 2020
 
Description Using pneumococcal carriage and invasiveness to inform vaccine policy in tropical Africa (CB) 
Organisation Kenyan Institute for Medical Research (KEMRI)
Country Kenya 
Sector Public 
PI Contribution study statistician
Collaborator Contribution design and coordination of the study
Impact no papers yet. Multi-disciplinary: epidemiology, genetics, statistics
Start Year 2019
 
Description VITALITY 
Organisation Biomedical Research and Training Institute (BRTI)
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution Study design, analysis
Collaborator Contribution Study design, implementation and evaluation
Impact Multidisciplinary: clinical medicine, epidemiology, clinical trials, health economics
Start Year 2020
 
Description VITALITY 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Study design, analysis
Collaborator Contribution Study design, implementation and evaluation
Impact Multidisciplinary: clinical medicine, epidemiology, clinical trials, health economics
Start Year 2020
 
Description VITALITY 
Organisation University of Lusaka
Country Zambia 
Sector Academic/University 
PI Contribution Study design, analysis
Collaborator Contribution Study design, implementation and evaluation
Impact Multidisciplinary: clinical medicine, epidemiology, clinical trials, health economics
Start Year 2020
 
Description VITALITY 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Study design, analysis
Collaborator Contribution Study design, implementation and evaluation
Impact Multidisciplinary: clinical medicine, epidemiology, clinical trials, health economics
Start Year 2020
 
Description Y-CHECK 
Organisation National Institute for Medical Research, Tanzania
Department Mwanza Intervention Trials Unit (MITU)
Country Tanzania, United Republic of 
Sector Public 
PI Contribution Study design
Collaborator Contribution Study design, implementation
Impact Multidisciplinary: epidemiology, public health
Start Year 2018
 
Description Y-CHECK 
Organisation University of Ghana
Country Ghana 
Sector Academic/University 
PI Contribution Study design
Collaborator Contribution Study design, implementation
Impact Multidisciplinary: epidemiology, public health
Start Year 2018
 
Description Y-CHECK 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution Study design
Collaborator Contribution Study design, implementation
Impact Multidisciplinary: epidemiology, public health
Start Year 2018
 
Description Zvatinoda! 
Organisation Organization for Public Health Interventions and Development
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution Study design, project coordination
Collaborator Contribution Study design and coordination, fieldwork, liaison with policy makers, digital intervention expertise
Impact none yet. Multidisciplinary: Epidemiology, social science, implementation science
Start Year 2019
 
Description Zvatinoda! 
Organisation The SHM Foundation
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Study design, project coordination
Collaborator Contribution Study design and coordination, fieldwork, liaison with policy makers, digital intervention expertise
Impact none yet. Multidisciplinary: Epidemiology, social science, implementation science
Start Year 2019
 
Description 5th Southern Africa Malaria Research Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Oral presentation presenting results of CRT on reactive focal malaria elimination interventions in Namibia
Year(s) Of Engagement Activity 2019
 
Description AMR STI Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 2 day conference tp bring together experts working at the interface of AMR and STI research, policy and practice with a view to identifying bottlenecks and solutions for tackling STI AMR and developing short and long term action plans
Year(s) Of Engagement Activity 2020
URL https://www.lshtm.ac.uk/newsevents/events/global-local-addressing-threat-amr-sti-control
 
Description ASTMH conference (JB) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Oral presentation at ASTMH conference
Year(s) Of Engagement Activity 2019
 
Description ASTMH: Symposium on PBO Nets 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Symposium on New Generation Long Lasting Insecticide Treated Nets for malaria prevention
Year(s) Of Engagement Activity 2019
 
Description Adolescent Health 2019 Coming of Age 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Prof Helen Weiss, oral presentation at Adolescent Health - Coming of age conference held by RCPCH
Year(s) Of Engagement Activity 2019
 
Description BBC world service interview 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact BBC World Service interview in response to second recorded case of "cure" from HIV announced at CROI
Year(s) Of Engagement Activity 2019
 
Description CROI/ ISSTDR/ IAS 2019 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Talks on PopART trial results at CROI, IAS and ISSTDR conferences in 2019
Year(s) Of Engagement Activity 2019
 
Description Ending Period Poverty Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Workshop on ending period poverty by 2030, bringing together researchers, funders, policy makers and practitioners to discuss how to use evidence to develop and deliver menstrual health policies and programmes.
Year(s) Of Engagement Activity 2017,2019
 
Description Feminem Podcast 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Podcast on careers in epidemiology and gender equity in leadership
Year(s) Of Engagement Activity 2019
 
Description HAYA Adolescent health research dissemination 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Following the HAYA research programmed in KwaZulu-Natal, South Africa. Young people co-created and performed songs and films to share messages from the research with their peers and other stakeholders.
Year(s) Of Engagement Activity 2019
 
Description IAS 2018 (KS) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Evaluating uptake of anti-retroviral treatment irrespective of CD4 count
Year(s) Of Engagement Activity 2018
 
Description Imperial University invited talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Invited seminar to promote good trial methodology
Year(s) Of Engagement Activity 2019
 
Description Joint WHO-Wageningen University of Research Global Vector Control Response conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Oral Presentation on Insecticides and Malaria Control
Year(s) Of Engagement Activity 2019
 
Description King College invited seminar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Invited seminar to promote good trial methodology
Year(s) Of Engagement Activity 2019
 
Description Media interviews around release of primary results of PopART trial 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Media interviews around the publication of the primary results of the PopART trial
Year(s) Of Engagement Activity 2019
 
Description Mental Health World Congress News 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Interview in Mental Health World Congress Magazine about menstrual health research in the context of school mental health and school drop out
Year(s) Of Engagement Activity 2019
 
Description Networking Breakfast 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact TEG networking breakfast at LSHTM - approx 20 LSHTM staff attended a talk designed to promote TEG's work and encourage new collaborations
Year(s) Of Engagement Activity 2019
 
Description Pint of Science (SN) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Public talk about trial in Uganda and South Africa, as part of national science festival
Year(s) Of Engagement Activity 2019
 
Description PopART and UTT 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Talk at Francis Crick Institute for World AIDS Day 2019
Year(s) Of Engagement Activity 2019
 
Description STI Vaccine Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Workshop on the need for STI vaccines/bottlenecks for development & implementation, bringing together researchers, policy makers and clinicians
Year(s) Of Engagement Activity 2019
URL https://www.lshtm.ac.uk/newsevents/events/sti-vaccine-workshop-innovations-impact
 
Description SUSAN-SSACAB conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Six previous TEG fellows attended, presented abstracts & discussed to strengthen the network, to share expertise, collaborate on common projects. Also contributed to discussions on how TEG can contribute to the SSACAB initiative for capacity building in SSA
Year(s) Of Engagement Activity 2019
 
Description Talks on PopART trial results 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Talks on PopART trial results given at University of Third Age, Francis Crick Institute and other organizations
Year(s) Of Engagement Activity 2019
 
Description The Behaviour Insights Team stepped wedge trial talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Invited seminar at a social purpose company part owned by the cabinet office to promote good trial methodology
Year(s) Of Engagement Activity 2019
 
Description Young Scientists (SN) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Around 12-20 local school pupils (age 14-18) attend LSHTM for 1-2 weeks. They design and carry out a piece of scientific research, supported by academic staff and postgraduate student mentors. They then present their results to an open seminar. Held three times per year.
Year(s) Of Engagement Activity 2019