MRC Centre for Global Infectious Disease Analysis

Lead Research Organisation: Imperial College London
Department Name: School of Public Health

Abstract

The continuing threat from new infectious diseases has been highlighted in recent years by the emergence of MERS-coronavirus in the Middle East, Ebola in West Africa and Zika in Latin America. Preparing for and responding to such threats is a priority for public health agencies and governments worldwide. Equally importantly, as scientific research delivers new approaches to controlling existing infectious diseases such as malaria, HIV, tuberculosis and polio, there is a need to determine what interventions are likely to work best to limit the disease and illness caused by a specific disease in a particular setting.

In this context, computer modelling of the spread of diseases in populations coupled with scientifically rigorous data analysis have proven themselves as powerful tools for giving insight into how diseases spread and what can be done to limit that control that spread. The Centre for Global Infectious Disease Analysis undertakes research on these scientific methods and applies them to disease threats of concern.

A key feature of the Centre is the close links it has made with with public health agencies - such as the Public Health England, the Centers for Disease Control and Prevention in the US (CDC), and the World Health Organization (WHO) - organisations which have to formulate and implement strategies to control infectious diseases.

Senior scientists in the Centre are world-leaders in infectious disease modelling and analysis. They have broad experience in responding to real epidemics, and undertaking epidemiological research on endemic diseases (such as malaria, HIV, tuberculosis and polio). Their work directly influences disease control policy through the many interactions the Centre has with public health organisations and governments.

Funding provided by MRC and Imperial College has allowed dedicated investment into the development of close collaborative partnerships with PHE, CDC and WHO and governments and research centres in many low and middle income countries (LMICs). We also work closely with other important organisations who work on improving health in LMICs (notably the Bill and Melinda Gates Foundation, The Global Fund and Gavi). With each, our collaborative research has both scientific interest to Centre researchers and contributes to the evidence base for public health decisions. Centre funding supports a core technical capacity available to all projects and pays for dedicated liaison staff who facilitate and enhance our partnerships with major global health organisations and LMICs.

MRC funding has also facilitated a greater focus on collaboration, training and career development within the Centre - training the next generation of quantitative infectious disease epidemiologists. We are also involved in increasing knowledge of advanced modelling methods in public health institutions and the wider infectious disease research community, and so have run a large number of introductory short-courses and workshops (in 13 countries in the last 5 years)

This applied activity depends on more fundamental research undertaken in the Centre on the transmission dynamics of different diseases, how diseases evolve genetically over time, and on analysing new approaches to control or treat diseases. This research is interdisciplinary, with Centre researchers working with leading clinical and experimental scientists around the world.

Continued Centre funding will allow existing partnerships to be sustained and enhanced, and new collaborations with researchers and health agencies in LMICs to be developed. By supporting PhD training and postdoctoral career development, it will also continue to expand the UK skill base in mathematical modelling and advanced analysis applied to health problems. Last, continued MRC support will pump-prime new priority research areas, including work on improving the development of new vaccines and on tackling the global challenge posed by antimicrobial resistance.

Technical Summary

The continued threat posed by emerging infectious diseases has been highlighted in recent years by the emergence of MERS-coronavirus in the Middle East, Ebola in West Africa and Zika in Latin America. Preparedness therefore remains a policy priority for public health agencies and governments worldwide. In addition, as new vaccines, drugs and other interventions are developed for endemic diseases such as malaria, HIV and TB, there is a need to extrapolate from clinical trial results to determine which combination of interventions gives the optimal (or most cost-effective) control strategy for a specific disease in a particular setting.

In this context, modern epidemiological modelling and analysis methods have proven themselves increasingly powerful tools for giving insight into the patterns of emergence of novel outbreaks, the transmission dynamics of endemic diseases and the options available for the control of both. The Centre for Global Infectious Disease Analysis is a world leader in research in this area, and in translating our research into improved public-health decision-making. Since it was founded, MRC funding has supported this translation by facilitating the forging of close partnerships with all major global health organisations (e.g. WHO, PHE, CDC, BMGF, The Global Fund, Gavi) and research centres and public health agencies in many low and middle income countries (LMICs).

Continued funding for the Centre will allow existing partnerships to be sustained and enhanced, and new collaborations with researchers and health agencies in LMICs to be developed. By supporting PhD training and postdoctoral career development, it will also continue to expand the UK skill base in mathematical modelling and advanced analysis applied to health problems. Last, continued MRC support will pump-prime new priority research areas, including work on improving the development of new vaccines and on tackling the global challenge posed by antimicrobial resistance.

Planned Impact

A primary aim of the MRC Centre for Global Infectious Disease Analysis is to have societal as well as academic impact - both in the UK and across the world. Our goal is to improve public and global health decision making in relation to infectious disease control through the use of advanced statistical and mathematical modelling methods, whether in emergencies like the West African Ebola epidemic in 2014, or in improving control of major infectious disease killers like HIV, malaria and Tuberculosis. We believe the only effective way of delivering on this goal is to form long-term collaborative partnerships with the leading public and global health organisations world-wide, providing analytical support and capacity building for those partners.

Since the Centre was founded in 2008, we have worked on dozens of policy-relevant problems with decision-makers around the world. We provided real-time support to the World Health Organization (WHO), the governments of the UK, and many other international partners during the 2001 H1N1 influenza pandemic, in relation to continued outbreaks of MERS coronavirus in the Middle East, during the 2014-15 West African Ebola epidemic, and, most recently, during the Latin American Zika epidemic. In addition, we have worked closely with WHO and the major international organisations (e.g. The Global Fund, Gavi and the Bill and Melinda Gates Foundation [BMGF]) that fund infectious disease control efforts in low income countries on HIV, malaria, tuberculosis, polio, influenza and a wide range of other diseases. Our relationship with BMGF is of particular strategic importance - it is both the largest funder of Centre research, but more importantly is a key stakeholder in global health decision-making.

These interactions, and our consequent impact on policy, is facilitated by staff dedicated to acting as liaisons between the scientists working in the Centre and the staff of the global and public health agencies we work with. Indeed, in times of crisis, we embed our staff in some of those key organisations. Recently, one of our researchers joined a WHO field mission to the Democratic Republic of Congo to help that country respond to an outbreak of Ebola.

In addition to formal research outputs, often the most important value we give to these organisations is advice provided from a dynamical modelling perspective. This analytical advisory role is multifaceted: from improving situational awareness in crises, advising on likely impact of interventions for endemic diseases, undertaking rapid analyses of priority questions, and advising on improving surveillance and data capture systems.

Capacity building within our partners is another priority, through informal skills transfer and formal training. The former occurs as a natural result of the degree of interaction, and for the latter we run short-courses, both in the Centre and at our partners' sites. Increasingly, we have also been undertaking capacity-building in low and middle income countries [LMIC], either by running disease-specific workshops with local ministries of health, or by training able local scientists. This activity will be further emphasised in the future.

In addition to impact on public health, we have also been increasing our collaborations with the pharmaceutical industry, most notably with vaccine manufacturers. In the last 5 years we have worked closely with GSK and Sanofi Pasteur, helping to characterise the effectiveness of their malaria and dengue vaccines, respectively. Our work involved analysing the data those companies collected on their products during clinical trials and advising them, WHO and regulatory agencies on how their vaccines might best be used. We also work with a wide range of public-private product development partnerships developing new vaccines, drugs and vector control measures.

Attached letters of support from UK DoH, GoS, PHE, US CDC, WHO and BMGF highlight the public health impact of the Centre.

Organisations

Publications

10 25 50

 
Description Active case finding in South India
Geographic Reach Asia 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Modelling analysis helped local authorities in their decision making for how to implement a highly resource intensive activity (active case finding) in a more efficient way. Guidance allowed a 20% increase in numbers of x-rays being diagnosed for TB. Awaiting further data to assess further impact on patient outcomes.
 
Description Advise to Chinese government to set up national procurement
Geographic Reach Asia 
Policy Influence Type Participation in a advisory committee
Impact Centralized national procurement process for pharmaceuticals was established in China based on this advise, launched in 2018.
 
Description Advising on global polio policy to the Global Polio Eradication Initiative
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Guidance on vaccine choice during polio eradication endgame, release of global stockpile, development of a new oral poliovirus vaccine
 
Description Advisory Board of Parasites & Vectors
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Shaping up the scope of the journal; engagement with contributors; advising the Editor-in-Chief
 
Guideline Title 2018 BASHH UK national guideline for the management of infection with Mycoplasma genitalium
Description British Association for Sexual Health and HIV guidelines on public health management of Mycoplasma genitalium and antimicrobial resistance
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
URL https://www.bashh.org/news/news/bashh-launches-new-nice-accredited-guidelines-to-help-prevent-mycopl...
 
Description Chair of Oriole Global Health Limited
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Chair of OGH Limited which is helping UK Aid and DFID deliver the ASCEND project for the control of NTDs in resource poor settings.
URL https://orioleglobalhealth.com
 
Description Citation in Blackett review
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://www.gov.uk/government/publications/computational-modelling-blackett-review
 
Description Citation in GAVI decision to support HBV birth dose
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
URL https://www.gavi.org/our-alliance/strategy/vaccine-investment-strategy
 
Description Co-wrote a WHO protocol for assessing non-inferiority of bednets and indoor residual sprays
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact We have devised a protocol to enable novel vector control products that are part of an existing intervention class to be recommended by the WHO (and therefore purchased by the Global Fund) without the need to go through expensive randomised control trials. Update 2020 - The policy was refined and accepted by the Malaria Programme Advisory Comittee at the WHO. New bednets are currently being distributed across Africa which are predicted to have a significant public health benefit to the people using them.
 
Description Collaboration with WHO Global Malaria Programme
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact This publication was cited in new policy guidance for the use of current rapid diagnostic tests for malaria, including guidance on when to switch test type if resistance mutations are present.
URL https://www.who.int/malaria/mpac/en/
 
Description Commonwealth Heads of Government Malaria Committment
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
URL https://www.malariasummit.com/
 
Description Comparison of different brands of bed nets
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Determine methods to ensure that bed nets procured by governments and charitable organisations are of an efficient standard
 
Description Contribution to Kenya's National Strategic Plan for TB control
Geographic Reach National 
Policy Influence Type Citation in other policy documents
 
Guideline Title HBV prevention of mother-child transmission
Description Contribution to and citation in WHO guideline for HBV prevention of mother-child transmission
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in clinical guidelines
 
Description Directing London Centre for NTD research - Helping deliver impact in the control of infectious diseases in resource poor settings
Geographic Reach Multiple continents/international 
Policy Influence Type Gave evidence to a government review
Impact Creation of an evidence base of how best to control NTDs. Influence on WHO guidelines for disease control and funding by philanthropic organisations, (GATES and CIFF). Guidelines hope to improve health in resource poor settings.
URL https://www.lshtm.ac.uk/newsevents/news/2013/ntd_research_launch.html
 
Description EU policy on banning trade in vector species infected with Batrachochytrium salamandrivorans fungus
Geographic Reach Europe 
Policy Influence Type Citation in other policy documents
Impact Biosecurity-relevant policy on banning the import of vector species with a view to stopping the introduction of Batrachochytrium salamandrivorans into the EU
URL https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32018D0320&from=EN
 
Description Elimination Scenario Planning Exercise with Senegal & The Gambia
Geographic Reach Africa 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Supported by The Global Fund, in 2016-2017 we undertook three workshops to support malaria country programme planning with The Gambia and Senegal. The last of these, in March 2017, was a joint workshop between the two programmes in which we coordinated discussions surrounding cross-border collaboration between the two countries. Our role in supporting the establishment of this new collaboration was acknowledged at the Malaria Summit held ahead of the Commonwealth Heads of Government meeting by the President of The Gambia (see URL below - we are mentioned in the film). A formal collaboration between the two countries was signed in January 2019.
URL https://www.malariasummit.com/
 
Description GAVI Vaccine Investment Strategy
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact Membership of the GAVI Vaccine Investment Strategy Committee which provided the scientific input for the recommendation of new vaccines to be supported by GAVI in the upcoming replenishment. This has a direct impact on worldwide childhood vaccination strategies.
URL https://www.gavi.org/about/strategy/vaccine-investment-strategy/
 
Description HPCs-UNAIDS
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a national consultation
 
Description HPCs-Zimbabwe
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description Informing strategic priorities for TB elimination in Mumbai, India
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
 
Description Malaria Policy Advisory Committee
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact This committee provides advice directly to the WHO Global Malaria Programme on all topics relevant to malaria control and elimination. WHO guidance has direct impact on the policies adopted by national government, which over the past year has included amendment of treatment protocols, advice on current and new prevention interventions, allocation of global donor funding and certification of malaria elimination.
URL https://www.who.int/malaria/mpac/en/
 
Description Member of Executive Management of Neglected Tropical Disease Modelling Consortium
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description Member of Influenza Incidence Analytics Group
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description Member of expert group for MoD (Confidential)
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
 
Description Membership of WHO Technical Advisory Group on Health benefit packages
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact Issue WHO guidance on how to design healthcare packages eg Universal Healthcare Coverage
 
Description Membership of regional WHO advisory committee on multi-drug-resistant TB in South East Asian Region
Geographic Reach Asia 
Policy Influence Type Participation in a advisory committee
 
Description Methods development for global HIV estimates and projections
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact We developed new mathematical models used to estimate and project trends in the global HIV epidemic. These models are used by all countries in sub-Saharan Africa and over 150 countries globally to develop official national estimates of their HIV epidemic and plan, budget, and allocate resources to the HIV response. Estimates are reported by UNAIDS as official global HIV estimates and projection, and they form consensus estimates underpinning resource allocation by the US President's Emergency Plan for AIDS Relief (PEPFAR) and the Global Fund to fight HIV, TB, and Malaria.
URL http://aidsinfo.unaids.org
 
Description NERVTAG (New and Emerging Respiratory Virus Threats Advisory Group) - Since 2015
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
URL https://www.gov.uk/government/groups/new-and-emerging-respiratory-virus-threats-advisory-group
 
Description Pandemic influenza preparedness - advice to government
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Impact Effective preparedness and response to pandemics, which are the highest category of risk identified on the National Risk Register of Civil Emergencies. This is an ongoing activity, supported by multiple relevant grants spanning different time-periods. Updated 2020: Involvement in coronavirus real time analysis and advice
 
Description Participation in WHO consultation process for setting the 2030 Roadmap on Neglected Tropical Diseases
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Report of the consultation meeting by the WHO - Neglected Tropical Disease Modelling Consortium Report Open Letter for Gates Open Research on Onchocerciasis, Chagas Disease and Taeniasis/Cysticercosis - contribution by ICL by highlighting insights from mathematical modelling in these 3 disciplines for the achievement of the 2030 NTD goals. Will result in increases in survival. improved quality of life for patients, decrease in disease burden and infection. This modelling can be used with economic modelling to assess the cost effectiveness of the interventions modelled.
URL https://www.who.int/neglected_diseases/news/WHO-launches-global-consultations-for-new-NTD-Roadmap/en...
 
Description Presentation and participation in WHO Technical Consultation in Research priorities for the use of more highly sensitive diagnostics during pregnancy
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
URL https://www.who.int/malaria/mpac/mpac-april2018-hi-sensitive-tests-session5.pdf?ua=1
 
Description Publication of work about Evidence Synthesis for Policy
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
URL https://royalsociety.org/topics-policy/projects/evidence-synthesis/
 
Description Published estimates of Impact of President's Malaria Initiative used in 12th annual report to congress
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Our estimates, published in PLoS Medicine, of the impact of the PMI since it's conception were used by PMI in it's report to congress. This report is used to advocate for resources for malaria prevention across 19 focus countries, amid a time when the US' contribution to foreign aid was being questioned.
URL https://www.pmi.gov/docs/default-source/default-document-library/pmi-reports/2018-pmi-twelfth-annual...
 
Description RDTs-WHO
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a national consultation
Impact Evidence generated on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment contributed to a decision in Zimbabwe (and possibly elsewhere) to adopt a World Health Organisation recommendation to implement repeat HIV testing prior to initiating people onto antiretroviral treatment. This change in policy will reduce the numbers of HIV-negative people put on potentially life-long treatment, will reduce the occurrence of unnecessary side effects, and will reduce unnecessary expenditure.
 
Description Scientific Advisory Group for Emergencies (SAGE) - Covid-19
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description Scientific Pandemic Influenza Group on Modelling (SPI-M-O) (since 2009)
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
URL https://www.gov.uk/government/publications/spi-m-publish-updated-modelling-summary
 
Description Scientific committee for Pandemic Influenza - Modelling (SPI-M)
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Impact Evidence given to SPI_M committee directly influenced early messaging about the severity of COVID-19.
URL https://www.gov.uk/government/groups/scientific-pandemic-influenza-subgroup-on-modelling
 
Description Strategic Technical Advisory Group for Infectious Hazards at WHO
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Influence on continued operational response for Ebola outbreak in DRC - has led to increased situational awareness of epidemiological trends. HAs led to improved service provision from international organisations.
URL https://www.who.int/emergencies/diseases/strategic-and-technical-advisory-group-for-infectious-hazar...
 
Description Support MSF surveillance of malaria policy
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Provided evidence to allow MSF to monitor malaria severity using antinatal clinic data
URL http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114784
 
Description Support the development of guidelines for malaria surveillance in near-elimination settings. We have outlined a set of questions that should be asked to estimate whether an identified case of malaria was acquired locally or imported from abroad. These include statements on the time and location of travel, duration of stay and date of arrival of symptoms. Questions trailed in regions of South Africa.
Geographic Reach Africa 
Policy Influence Type Influenced training of practitioners or researchers
 
Description TB control priorities in India
Geographic Reach Asia 
Policy Influence Type Gave evidence to a government review
 
Description Talk given to All Party PArliamentary Group on Biosecurity re COVID-19
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
URL https://www.parliament.uk/mps-lords-and-offices/offices/bicameral/post/post-events/future-biosecurit...
 
Description Typhoid environmental surveillance advisory group for the Gates Foundation
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description UNAIDS reference group
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact From 2015 to 2018, I co-chaired the UNAIDS Reference Group on Estimates, Modelling and Projections. This group advises UNAIDS and WHO on the methods used to generate international estimates of HIV infection and it's demographic impact. During this period, significant progress was made in improving these estimates - for example, for children infected with HIV, by incorporating age-structure into the models, and in producing local estimates of levels of HIV infection - that can be used to strengthen national HIV control programmes and, thereby, to further reduce levels of new infections and mortality.
URL http://www.epidem.org/
 
Guideline Title WHO Dengue Vaccination recommendation
Description WHO Dengue Vaccination recommendation
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in clinical guidelines
Impact Recommendations on optimal vaccine use has led to changes in the delivery of vaccines in relevant populations
URL https://www.who.int/wer/2016/wer9130.pdf?ua=1
 
Description WHO Flu Burden
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description WHO policy of recommending the use of second-in-class bednets against malaria
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact Impacts not yet recognised
 
Description WHO spread of pyrethroid resistant mosquitoes across Africa.
Geographic Reach Africa 
Policy Influence Type Participation in a advisory committee
Impact Collaboration with the World Health Organisation (WHO) Global Malaria Programme to understand the spread of pyrethroid resistant mosquitoes across Africa and how this influences the effectiveness of insecticide treated bednets used to control malaria. Though this has not led to any specific policy recommendations the work was presented in a WHO document (World Malaria Report 2019, Global report on insecticide resistance in malaria vectors: 2010-2016, accessed https://www.who.int/malaria/publications/atoz/9789241514057/en/ ) and on a live WHO webinar (https://apps.who.int/iris/bitstream/handle/10665/274556/WHO-CDS-GMP-2018.17-eng.pdf?ua=1). This work has supported the development of online threat maps for insecticide resistance status (https://www.who.int/malaria/maps/threats-about/en/).
URL https://www.who.int/malaria/publications/atoz/9789241514057/en/
 
Description WHO world malaria report
Geographic Reach Africa 
Policy Influence Type Citation in other policy documents
Impact Tracking of ITN numbers and use
 
Description World Malaria Report 2019
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Published estimates of exposure and burden of malaria during pregnancy and associated Low birthweight were incorporated into official WHO estimates underpinning the World Malaria Report estimates of malaria burden and progress.
URL https://www.who.int/publications-detail/world-malaria-report-2019
 
Description Zimbabwe national AIDs council - workshop on HIV prevention cascade
Geographic Reach Africa 
Policy Influence Type Participation in a national consultation
 
Description A genealogical approach to tracking bacterial transmission (Xavier Didelot)
Amount £403,170 (GBP)
Funding ID MR/N010760/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 05/2016 
End 05/2019
 
Description A search-engine inspired platform enabling open sharing and access of both data and results from all genomic studies
Amount £38,832 (GBP)
Funding ID 219699/Z/19/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2020 
End 01/2021
 
Description ALPHA network: HIV incidence trends and risk factors to describe patterns and risks for HIV incidence in selected communities in Southern and Eastern Africa
Amount £170,846 (GBP)
Funding ID EPPHZM5513/Imperial 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2018 
End 09/2020
 
Description APW WHO Global Malaria Programme
Amount £17,932 (GBP)
Funding ID 202011200 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 06/2018 
End 03/2019
 
Description Analysis of ALPHA Network
Amount £37,490 (GBP)
Funding ID PR2017/724002 EPPHZL91/IMPERIAL 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 12/2017 
End 11/2018
 
Description Analytic and sequencing tools for poliovirus environmental surveillance
Amount £876,522 (GBP)
Funding ID OPP1171890 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 05/2017 
End 11/2020
 
Description Antibiotic Resistance: Mathematical modelling simulating the evolutionary response of genococcus within human populations to gepotidacin use
Amount £151,716 (GBP)
Funding ID 3000862100 
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start 06/2017 
End 06/2019
 
Description Assessing the impact of waning vaccine efficacy on malarial elimination using a population transmission model
Amount £61,597 (GBP)
Funding ID GAT.0888-30-01320457-COL 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2016 
End 11/2018
 
Description Assessing the risk that chytridiomycosis poses to the megadiverse amphibian community of Madagascar
Amount £119,900 (GBP)
Funding ID D16ZO-022 
Organisation Morris Animal Foundation 
Sector Private
Country United States
Start 09/2016 
End 04/2020
 
Description BMGF Project Grant: Vaccine Modelling Initiative (VMI) 2
Amount £970,053 (GBP)
Funding ID OPP1092240 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 06/2013 
End 06/2020
 
Description Building International Collaborations on the Mathematical Modelling of Emerging Infectious Disease Threats (Neil Ferguson)
Amount £49,657 (GBP)
Funding ID P11329/DF118 
Organisation Imperial College London 
Department Imperial College Trust
Sector Charity/Non Profit
Country United Kingdom
Start 04/2008 
End 12/2020
 
Description Building TRUST
Amount £112,438 (GBP)
Funding ID Sub Award No. 1800014 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 07/2015 
End 06/2019
 
Description Control of TB in India: developing analytical tools
Amount £385,936 (GBP)
Funding ID OPP1095710 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2013 
End 03/2020
 
Description Defining disease importation and target interventions from routine surveillance data
Amount $100,000 (USD)
Funding ID OPP1161898 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2016 
End 04/2018
 
Description Develop a novel, cost-effective, surveillance approach for malaria elimination through existing antenatal care platform
Amount £56,255 (GBP)
Organisation PATH 
Sector Charity/Non Profit
Country Global
Start 02/2018 
End 08/2018
 
Description Developing modelling approaches for influenza control in the USA
Amount £210,020 (GBP)
Funding ID BAA 75D301-19-R-67835 
Organisation Centers for Disease Control and Prevention (CDC) 
Sector Public
Country United States
Start 08/2019 
End 08/2020
 
Description Development and pilot implementation of rapid poliovirus detection and sequencing from stool samples using nanopore technology
Amount £197,654 (GBP)
Funding ID OPP1207299 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2018 
End 03/2020
 
Description Development of Methods to Measure and Interpret HIV Prevention Cascades in Population-Based Surveys
Amount £766,317 (GBP)
Funding ID OPP1161471 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2016 
End 07/2020
 
Description Deworm3 unit for transmission dynamics, trial simulation and data analysis
Amount £1,163,766 (GBP)
Funding ID SON15004 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 04/2016 
End 09/2020
 
Description Dynamic Modelling of HSV-2 and HIV Infections to Estimate the Burden of HSV-associated HIV Infections and the Predicted Impact of HSV Vaccines
Amount £111,917 (GBP)
Funding ID 202002015 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 05/2018 
End 12/2019
 
Description Early antiretroviral therapy and pre-exposure prophylaxis for HIV prevention among emale sex workers in Benin, West Africa
Amount £121,857 (GBP)
Funding ID OPP1098973 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 08/2014 
End 12/2018
 
Description Epidemiological analysis and mathematical modelling of poliovirus elimination and endgame vaccination strategies
Amount £236,130 (GBP)
Funding ID 2017/769688-0 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 11/2017 
End 08/2019
 
Description Evaluation work by LCNTDR for the Geshiaro project in support of EPHI
Amount £383,276 (GBP)
Funding ID R-1701-01771 
Organisation Children's Investment Fund Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2018 
End 06/2023
 
Description Evolutionary dynamics underlying pneumococcal genomic diversity
Amount £640,778 (GBP)
Funding ID 104169/Z/14/A 
Organisation Sir Henry Dale Fellowships 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2019 
End 09/2022
 
Description Evolutionary dynamics underlying pneumococcal genomic diversity.
Amount £708,513 (GBP)
Funding ID 104169/Z/14/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2014 
End 09/2019
 
Description Explore the Pathway of China NICE-like Mechanism by Piloting Three Suggested Projects
Amount £172,623 (GBP)
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 12/2017 
End 05/2019
 
Description Fellow Marga Pons Salort (Emergence and global epidemiology of non-polio enteroviruses)
Amount £909,233 (GBP)
Funding ID 216427/Z/19/Z 
Organisation Sir Henry Dale Fellowships 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2020 
End 12/2024
 
Description Geospatial modelling for malaria risk stratification and intervention targeting
Amount £219,507 (GBP)
Funding ID 1606H5002/JH6 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2016 
End 08/2020
 
Description HC-HIV modeling activity
Amount £156,940 (GBP)
Funding ID 48345 
Organisation United States Agency for International Development 
Sector Public
Country United States
Start 06/2017 
End 08/2018
 
Description HIV Modelling Consortium Renewal
Amount £3,527,347 (GBP)
Funding ID OPP1084364 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 06/2013 
End 01/2019
 
Description Human Infectious Challenge Vaccine (HIC vac) network
Amount £2,041,189 (GBP)
Funding ID MR/R005982/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 05/2018 
End 02/2020
 
Description Immunological investigation for the implenatation of Live Attenuated Influenza Vaccination
Amount £811,303 (GBP)
Funding ID MR/R021643/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 06/2018 
End 12/2021
 
Description Impact of maternally derived antibodies and microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants
Amount £255,266 (GBP)
Funding ID JXR11990 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 07/2015 
End 12/2018
 
Description Improving the efficacy of malaria prevention in an insecticide resistant Africa
Amount £162,798 (GBP)
Funding ID 200222/B/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2016 
End 10/2019
 
Description Integrating Ethics and Equity into Priority Setting for Universal Health Coverage: A Proof-of-Concept Study in South Africa
Amount £128,944 (GBP)
Funding ID 208045/Z/17/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2017 
End 01/2020
 
Description Joint estimation of HIV and adult mortality trends in sub-Saharan Africa
Amount £67,680 (GBP)
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 08/2018 
End 12/2019
 
Description Key populations and HIV epidemics in Sub-Saharan Africa: Developing better epidemiologic tools to inform priorities and programs
Amount £179,258 (GBP)
Funding ID PO: 2003388501 
Organisation Family Health International 
Sector Charity/Non Profit
Country United States
Start 06/2016 
End 03/2019
 
Description Kris Parag: Minimum Models for Optimal Epidemic Monitoring and Control
Amount £288,432 (GBP)
Funding ID MR/S019693/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2018 
End 10/2021
 
Description London Centre for NTD Research
Amount £555,000 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start 06/2015 
End 05/2019
 
Description London Centre for NTD Research (renewal 3)
Amount £785,649 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start 06/2018 
End 05/2021
 
Description MIDAS 2: Models for synthesising molecular, clinical and epidemiological data, and translation to public health response (NIH)
Amount £1,246,328 (GBP)
Funding ID 1U01GM110721-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2014 
End 05/2019
 
Description MIDAS: Modeling Epidemic Infectious Diseases Using Sequence Analysis
Amount £300,028 (GBP)
Funding ID 258162IMP 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2016 
End 05/2020
 
Description Malaria Eradication Metrics
Amount £222,688 (GBP)
Funding ID CRR00280 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 03/2019 
End 09/2021
 
Description Mapping the risk of international infectious disease spread
Amount £120,202 (GBP)
Funding ID AID-OAA-F-16-00115 
Organisation United States Agency for International Development 
Sector Public
Country United States
Start 10/2016 
End 12/2018
 
Description Mathematical Modelling of Microfilaricidal Drugs for River Blindness: from Patients to Populations
Amount £50,870 (GBP)
Organisation Drugs for Neglected Diseases initiative (DNDi) 
Sector Charity/Non Profit
Country Switzerland
Start 06/2016 
End 05/2019
 
Description Mathematical modeling in the HPTN Renewal
Amount £724,350 (GBP)
Funding ID 2UMIAI068617 Sub#0000800798 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2014 
End 11/2020
 
Description Mathematical modelling of poliovirus transmission to support the endgame
Amount £487,817 (GBP)
Funding ID OPP1099374 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2013 
End 07/2018
 
Description Model development for the draft WHO global report on insecticide resistance in malaria vectors
Amount £13,901 (GBP)
Funding ID 2018/797131-0 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 03/2018 
End 12/2018
 
Description Model development for the draft WHO global report on insecticide resistance in malaria vectors
Amount £258,706 (GBP)
Organisation IVCC 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2018 
End 02/2020
 
Description Modeling Anorectal HIV Transmission in Women
Amount £288,589 (GBP)
Funding ID 5R01AI057020 Sub#201224310-05 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 11/2014 
End 05/2019
 
Description Modelling antimalarial target product profiles for reducing P. falciparum malaria transmission
Amount £316,782 (GBP)
Funding ID PO14/00561 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2013 
End 02/2019
 
Description Modelling in support of India program , development and use of new tools and programmatic prioritization
Amount £247,862 (GBP)
Funding ID OPP1205227 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2018 
End 10/2020
 
Description Modelling the Elimination of Onchocerciasis in Cameroon (International Exchanges)
Amount £11,999 (GBP)
Funding ID IES/R2/181017 
Organisation The Royal Society 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2018 
End 12/2020
 
Description Modelling the Value of Vaccines in Reducing the Burden of Antimicrobial Resistance
Amount £53,674 (GBP)
Funding ID OPP1190803 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 06/2019 
End 04/2020
 
Description Modelling the potential impact of intermittent preventive treatment of malaria in pregnancy on antimalarial drug resistance
Amount £99,998 (GBP)
Funding ID ch160084 
Organisation Royal Society of Medicine 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2016 
End 08/2018
 
Description Modelling the spatiotemporal dynamics of arbovirus transmission: implications for disease control and elimination
Amount £969,469 (GBP)
Funding ID 213494/Z/18/Z 
Organisation Sir Henry Dale Fellowships 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2019 
End 08/2024
 
Description Multidisciplinary Studies of HIV/AIDS and Aging (R21)
Amount £205,531 (GBP)
Funding ID 1R21AG053093 - 01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2016 
End 07/2019
 
Description NIHR Senior Investigator Award
Amount £120,000 (GBP)
Funding ID P/O 427921 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2009 
End 04/2021
 
Description NIHR: NIHR HPRU in Modelling Methodology
Amount £4,234,300 (GBP)
Funding ID HPRU-2012-10080 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2014 
End 03/2020
 
Description NTD Consortium - CIFF Project
Amount £184,212 (GBP)
Funding ID MA4501202974 
Organisation Children's Investment Fund Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2015 
End 04/2018
 
Description NTD Consortium Renewal (STH, Schisto, Oncho)
Amount £770,936 (GBP)
Funding ID 1708CR001/VP1 (OPP1184344) 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2017 
End 02/2021
 
Description Near-Infrared Spectroscopy: A One-Stop-Shop for Mosquito Epidemiological Monitoring?
Amount £643,683 (GBP)
Funding ID MR/P01111X/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 03/2017 
End 02/2020
 
Description New Data and Models to Track Progress Towards Reducing New HIV Infections
Amount £861,803 (GBP)
Funding ID OPP1190661 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 05/2018 
End 03/2022
 
Description Newton Fund Researcher Links Grant
Amount £34,450 (GBP)
Funding ID 2016-RLWK7-10289 
Organisation British Council 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2017 
End 01/2018
 
Description Optimal spatial scales for deployment of multiple first line therapies for malaria
Amount £105,750 (GBP)
Funding ID RGF\EA180225 
Organisation Royal Society of Medicine 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2017 
End 03/2021
 
Description Phase variable epigenetic regulation in Firmicutes
Amount £298,700 (GBP)
Funding ID RM33G0360 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 01/2016 
End 12/2018
 
Description Population Effects of Antretroviral Therapy to Reduce HIV Transmission (PopART) - Health Economics
Amount £12,709 (GBP)
Organisation UK Department for International Development 
Sector Public
Country United Kingdom
Start 11/2015 
End 03/2018
 
Description Population Effects of Antretroviral Therapy to Reduce HIV Transmission (PopART) - Health Economics
Amount £502,745 (GBP)
Funding ID PO15001410 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2015 
End 01/2020
 
Description Predicting the impact of insecticide resistance and new paradigms of vector control
Amount £161,331 (GBP)
Organisation IVCC 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2015 
End 05/2018
 
Description Predicting the impact of seasonal respiratory infection on temporal dynamics and characteristics of admission rates and time spent in hospital
Amount £115,260 (GBP)
Funding ID RDA02 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 11/2018 
End 10/2020
 
Description Predicting the public health impact of SSM-VIMT Phase III and IV trials
Amount £19,617,788 (GBP)
Organisation Malaria GIA Reference Center - PATH MVI 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2018 
End 12/2019
 
Description Progestin-based contraceptive modeling in high DMPA-IM use and high HIV incidence settings
Amount £378,999 (GBP)
Funding ID OPP1194416 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2018 
End 07/2020
 
Description Projections on eliminating NTDs (integrating mapping with modelling)
Amount £73,998 (GBP)
Funding ID OPP1156227 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2016 
End 10/2018
 
Description Projections on eliminating NTDs (integrating mapping with modelling).
Amount £20,392 (GBP)
Funding ID CRR00140 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2017 
End 12/2019
 
Description Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections (2018-2019)
Amount £480,563 (GBP)
Funding ID 2017/778519 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 01/2018 
End 12/2019
 
Description Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections (2018-2019)
Amount £480,563 (GBP)
Funding ID 2017/778519 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 01/2018 
End 12/2019
 
Description Quantifying Spatial Representativeness and Uncertainty in Antenatal Care Sentinel Surveillance for HIV in Sub-Saharan Africa.
Amount $53,375 (USD)
Funding ID 1R03AI125001-01A1 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 12/2016 
End 11/2018
 
Description Quantifying and preparing for the non-communicable disease burden in the ageing HIV-positive population in Kenya
Amount £134,891 (GBP)
Funding ID OISE-17-62962-1 
Organisation United States President's Emergency Plan for AIDS Relief 
Sector Public
Country United States
Start 08/2017 
End 09/2019
 
Description R01 Statistical Models for Estimating and Projecting HIV/AIDS Epidemics
Amount £25,290 (GBP)
Funding ID 5776-ICS-DHHS-6664 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2017 
End 08/2019
 
Description Research and Development of Reconstructing HIV Epidemics from HIV Phylogenetics
Amount £72,683 (GBP)
Funding ID Ref: 340798 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2018 
End 06/2021
 
Description Research for Health in Conflict (R4HC): multi-sectorial capacity strengthening, partnership building and research across the MENA region
Amount £432,399 (GBP)
Funding ID MOTEAAR 
Organisation Kings BRC 
Sector Academic/University
Country United Kingdom
Start 10/2017 
End 12/2021
 
Description Respiratory Infection Health Protection Research Unit
Amount £93,377 (GBP)
Funding ID IS-HPU-1112-10064 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2014 
End 03/2020
 
Description RooPfs (Can improved housing provide additional protection against clinical malaria over current best practice? A household-randomised controlled trial)
Amount £179,101 (GBP)
Funding ID RF020305 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 11/2014 
End 10/2019
 
Description Schisto Vaccine project extn via NTD Modelling Consortium, Warwick
Amount £121,248 (GBP)
Funding ID OPP1176780 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2017 
End 03/2019
 
Description Sources and Impact of Misclassification Errors in HIV Rapid Testing Algorithms in a Hyper-Endemic HIV Setting in sub-Saharan Africa
Amount £886,781 (GBP)
Funding ID OPP1131208 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 07/2015 
End 09/2019
 
Description TB Modelling and Analysis Consortium
Amount £37,133 (GBP)
Funding ID EPIDZJ6210/Imperial 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 01/2018 
End 06/2019
 
Description Thanzi La Onse -Frameworks and analysis to ensure value-for-money health care: developing theory, changing practices in low- and middle-income settings.
Amount £687,266 (GBP)
Funding ID R18664 
Organisation Research Councils UK (RCUK) 
Sector Public
Country United Kingdom
Start 10/2017 
End 12/2021
 
Description The delay-care cascade and its implications for TB transmission: a study in three country settings
Amount £125,031 (GBP)
Organisation Stop TB Partnership 
Sector Charity/Non Profit
Country Switzerland
Start 08/2017 
End 12/2018
 
Description The evolution of influenza virus; Studies of within host and between host evolution to improve pandemic risk assessment and vaccine updates
Amount £1,269,464 (GBP)
Funding ID 200187/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2016 
End 03/2020
 
Description The farm environment: an overlooked reservoir of Mycobacterium bovis?
Amount £21,364 (GBP)
Funding ID RLFEW3022 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 04/2016 
End 05/2019
 
Description The life course of human immune responses to influenza infection and vaccination
Amount £1,882,747 (GBP)
Funding ID 200861/Z/16/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2016 
End 01/2021
 
Description Tracking the flow of malaria parasites and drug resistance within the DRC and across its borders
Amount £264,838 (GBP)
Funding ID 00001346 
Organisation National Institute of Allergy and Infectious Diseases (NIAID) 
Sector Public
Country United States
Start 11/2018 
End 05/2023
 
Description Understanding links between microbial communities and emerging fungal pathogens in complex ecosystems
Amount £394,290 (GBP)
Funding ID NE/S000844/1 
Organisation Natural Environment Research Council 
Sector Public
Country United Kingdom
Start 11/2018 
End 10/2021
 
Description Unravelling and predicting the spatiotemporal structure of infectious disease outbreaks
Amount £99,995 (GBP)
Funding ID SBF004/1080 
Organisation Academy of Medical Sciences (AMS) 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2019 
End 03/2021
 
Description Validation of New Technologies for Diagnostic Evaluation of Tuberculosis (VANTDET)
Amount £1,212,037 (GBP)
Funding ID 12/65/27 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 03/2014 
End 12/2017
 
Description Zika: A fast new intervention and an innovative method of evaluation
Amount £34,518 (GBP)
Funding ID AID-OAA-F-16-00094 
Organisation United States Agency for International Development 
Sector Public
Country United States
Start 10/2016 
End 09/2019
 
Description iDSI 2 (DFID Supplement)
Amount £1,494,209 (GBP)
Funding ID OPP1134345 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 04/2017 
End 03/2020
 
Title Development of an individual based model for stochastic simulations of onchocerciasis 
Description Individual host model incorporating complex life cycle in humans and vectors to investigate interventions against human onchocerciasis that may require targeting of individuals and/or age sex groups 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2019 
Provided To Others? Yes  
Impact This research tool is now being used for; business case for macrofilaricides, development of clinical trial simulators, epidemiological impact of moxidectin, assessment of anti-Wolbachia drugs for the treatment of filariases. 
URL https://www.ncbi.nlm.nih.gov/pubmed/?term=hamley%2C+basanez
 
Title Development of clinical trial simulators to guide clinical development of macrofilaricides 
Description Collaboration with Drugs for Neglected Diseases Initiative (Geneva) Adaptation of a stochastic simulation model of transmission to mimic characteristics of clinical trials to help assess; optimal sample sizes, optimal interim and end points, demonstrate superiority or non-inferiority of novel drugs in comparison with current therapies 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2019 
Provided To Others? No  
Impact Not known yet Paper under review in Nature Communications 
 
Title HPCs-integrated formulations 
Description Generic core and expanded formulations of HIV prevention cascades for use in tracking progress with implementation of efficacious methods of HIV prevention including combination HIV prevention. The core cascade is applied to a population at a given risk of HIV infection and comprises three steps - motivation to use the method(s), accessibility of the method(s), and effective use of the method(s). The core cascade can be used for high-level monitoring and advocacy. The expanded formulation adds factors that can contribute to drop-offs between the main steps in the core cascade which can aid identification of time- and place-specifically appropriate interventions to increase the level of effective use. These cascades can be used in mathematical models to measure the impact of current levels of use of HIV prevention methods on on HIV incidence and evaluate the potential impact of alternative interventions targeted at the different steps in the cascade (i.e. to improve motivation, accessibility and/or effective use). 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2019 
Provided To Others? Yes  
Impact This work contributed to a decision by UNAIDS to adopt HIV prevention cascades as an international framework for tracking progress with implementing primary methods of HIV prevention and to produce international guidelines for countries on formulations to use and methods of measurement. 
 
Title HPCs-questionnaire 
Description Questionnaire comprising questions to measure and interpret HIV prevention cascades for male and female condoms, pre-exposure prophylaxis, voluntary medical male circumcision, sexual partner reduction and combination HIV prevention in general population surveys. 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2018 
Provided To Others? No  
Impact None as yet - the tool is currently being piloted in a large population survey in east Zimbabwe 
 
Title RDTs-smartphone camera app 
Description Smartphone camera application developed by our collaborators on the study on HIV misclassification errors (Global Solutions for Infectious Diseases) to collect and transmit images of the outputs from HIV rapid tests used in routine health services - thereby enabling evaluation by external experts of the quality of outputs from these tests and the accuracy of interpretation of these outputs by local clinic staff. 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2016 
Provided To Others? No  
Impact The tool has enabled us to establish that approximately 50% of false-negative HIV test results occurring in routine health services in Zimbabwe could be due to errors by local clinic staff in reading or recording the outputs from HIV rapid tests. 
 
Title YZ-UHP! survey management portal 
Description Portal showing progress with conducting general population surveys on use of HIV prevention methods. 
Type Of Material Improvements to research infrastructure 
Year Produced 2018 
Provided To Others? No  
Impact Improvements in tracking progress against targets and errors/inconsistencies in the data requiring investigation and correction resulting in improved data completeness and quality. 
 
Title A dynamic power-law sexual network model of gonorrhoea outbreaks 
Description Generates a dynamic power-law sexual network 
Type Of Material Computer model/algorithm 
Year Produced 2019 
Provided To Others? Yes  
Impact Impacts not yet recognised 
URL https://github.com/lwhittles/simdynet
 
Title All-India TB Model 
Description Model developed in collaboration with India National TB Programme, combining the best available epidemiological and surveillance data to capture India's TB epidemic on a national level. The model now forms the basis for different modelling analyses, conducted by the group, relating to TB in India. 
Type Of Material Computer model/algorithm 
Year Produced 2018 
Provided To Others? Yes  
Impact Model is currently being used to help inform India Government on strategic priorities for TB control in the country Updated 2020: model is applied by Indian government for their updated national strategic plan 
 
Title Creation and analysis of clinical trial databases 
Description DW3, Gates funded clinical trail for control of soil transmitted helminths. Tumikia - Gates funder clinical trial for control of soil transmitted helminths Geshiyaro - CIFF funded clinical trial for control of schistosomiasis and soil transmitted helminths 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact Sophisticated analysis of data and scientific publications 
 
Title Data from: Effect of culling on individual badger Meles meles behaviour: potential implications for bovine tuberculosis transmission 
Description 1. Culling wildlife as a form of disease management can have unexpected and sometimes counterproductive outcomes. In the UK, badgers (Meles meles) are culled in efforts to reduce badger-to-cattle transmission of Mycobacterium bovis, the causative agent of bovine tuberculosis (TB). However, culling has previously been associated with both increased and decreased incidence of M. bovis infection in cattle. 2. The adverse effects of culling have been linked to cull-induced changes in badger ranging, but such changes are not well documented at the individual level. Using GPS-collars, we characterised individual badger behaviour within an area subjected to widespread industry-led culling, comparing it with the same area before culling and with three unculled areas. 3. Culling was associated with a 61% increase (95% CI 27-103%) in monthly home range size, a 39% increase (95% CI 28-51%) in nightly maximum distance from the sett, and a 17% increase (95% CI 11-24%) in displacement between successive GPS-collar locations recorded at 20-minute intervals. Despite travelling further, we found a 91.2 minute (95% CI 67.1-115.3 minute) reduction in the nightly activity time of individual badgers associated with culling. These changes became apparent while culls were ongoing and persisted after culling ended. 4. Expanded ranging in culled areas was associated with individual badgers visiting 45% (95% CI 15-80%) more fields each month, suggesting that surviving individuals had the opportunity to contact more cattle. Moreover, surviving badgers showed a 19.9-fold increase (95% CI 10.8-36.4 increase) in the odds of trespassing into neighbouring group territories, increasing opportunities for intergroup contact. 5. Synthesis and Applications: Badger culling was associated with behavioural changes among surviving badgers which potentially increased opportunities for both badger-to-badger and badger-to-cattle transmission of M. bovis. Furthermore, by reducing the time badgers spent active, culling may have reduced badgers' accessibility to shooters, potentially undermining subsequent population control efforts. Our results specifically illustrate the challenges posed by badger behaviour to cull-based TB control strategies and furthermore, they highlight the negative impacts culling can have on integrated disease control strategies. 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
 
Title Develop statistical methods for determining whether a cases of malaria was acquired in the country of detection or imported from abroad. 
Description Develop a Bayesian method of taking a persons travel history, details of malaria endemicity and seasonality of transmission and determining the percentage likelihood that the case of malaria was: (1) acquired at home, (2) imported from abroad, (3) imported from another region of the country (4) was of unknown origin. 
Type Of Material Data analysis technique 
Year Produced 2018 
Provided To Others? No  
Impact None as yet 
 
Title EPP-ASM model for estimation HIV epidemic trends 
Description The EPP-ASM model is a new demographic-structured model for estimating HIV epidemic trends in sub-Saharan Africa. Compared to previously existing tools, the new model better captures the demographic impacts of the HIV epidemic and improves estimates of recent HIV incidence trends in generalised epidemic settings. 
Type Of Material Computer model/algorithm 
Year Produced 2019 
Provided To Others? Yes  
Impact - Model implemented in 2019 version of Spectrum software (v5.73) supported by UNAIDS for global HIV estimates and projections in developed in 2019 (to be published June 2019). - Model and software code utilised for HIV estimation by the Global Burden of Disease study by the Institute for Health Metrics and Evaluation 
URL https://github.com/mrc-ide/eppasm
 
Title Experiments for detection of Plasmodium berghei infected Anopheles stephensi mosquitoes using near-infrared spectroscopy 
Description Spectra from uninfected, indected and infectious mosquitoes 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact None currently 
URL https://doi.org/10.5281/zenodo.1001720
 
Title Fluscape project dataset 
Description Serological data from a study in China 
Type Of Material Database/Collection of data 
Year Produced 2015 
Provided To Others? Yes  
Impact None yet 
URL http://www.fluscape.org
 
Title HPV and HIV vaccination model 
Description Mathematical model of HIV and HPV transmission to assess HPV vaccination and screening programme for cervical cancer elimination in South Africa. 
Type Of Material Computer model/algorithm 
Year Produced 2019 
Provided To Others? No  
Impact Development is still ongoing. As a result of development, funding was received from WHO to carry out further modelling analysis to provide guidance for the vaccination and screening programmes to reach cervical cancer elimination in countries with high HIV prevalence. 
 
Title HSV2 - HIV Model 
Description Mathematical model designed to estimate the contribution of HSV2 to HIV transmission and impact of HSV2 vaccination globally 
Type Of Material Computer model/algorithm 
Year Produced 2019 
Provided To Others? No  
Impact Resulted in publications that will inform WHO business investment case for development of HSV2 vaccine 
 
Title Harvard Consortium for the creation of an international Alzheimer's database 
Description Drawing together of multiple longitudinal cohort databases 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Publications in 'Brain', 'Neuroscience' and 'Lancet' 
 
Title Household survey in Eastern Zimbawe 
Description Conducting a household survey in Eastern Zimbawe to determine HIV risks as part of a 20 year old study. See Manicaland HIV project (.org) 
Type Of Material Database/Collection of data 
Year Produced 2007 
Provided To Others? No  
Impact This has been going on since 2007 and it is on-going 
 
Title International risk of disease spread due to air travel 
Description Model to establish the number of exported cases due to air travel during an outbreak. This has been applied to Zika, Yellow Fever and COVID-19. 
Type Of Material Computer model/algorithm 
Year Produced 2018 
Provided To Others? Yes  
Impact Model has been used to inform US CDC on the risk of importation of Yellow Fever from Brazil Model is used to advise on the need of travel restrictions and role of travellers vaccinations. Paper published in 2019 in Scientific Reports. 
URL https://www.nature.com/articles/s41598-019-56521-9
 
Title MARDY - Antifiungal Resistance Database 
Description Online database of anti fungal resistance alleles for multiple fungal pathogens 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact Published in 2018 
URL http://mardy.dide.ic.ac.uk
 
Title Malaria socio-economic data 
Description qualitative and quantitative data from several West African countries on perceptions of quality, risk, costs and cost effectiveness 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Too early to identify impacts 
 
Title Manicaland - HPCs 
Description SQL database comprising data from the baseline general population survey for a study to measure and interpret HIV prevention cascades and to evaluate the impact of novel behavioural economics and community psychology interventions to strengthen these cascades in adolescent girls and young women and their male partners. The database includes HIV infection data obtained from provider-initiated HIV testing and counselling (PITC) and, for those who decline PITC, from laboratory tests conducted using dried blood spots collected in the survey. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact None as yet - data collection still in progress 
 
Title Manicaland - cohort 
Description SQL database comprising data from 6 rounds of a general population cohort survey in Manicaland, east Zimbabwe, with linked HIV test results 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact Data describing and interpreting declines in HIV prevalence, HIV incidence and AIDS mortality within the general population over the period 1998 to 2013. Results have been published in more than 200 scientific papers including Science and The Lancet. The findings from the study led to our being requested by UNAIDS to conduct in-depth investigations into the existence and causes of national HIV decline in Zimbabwe. 
 
Title Manicaland - test & treat 
Description Database containing data extracted from routine programme records at health centres in three districts of Manicaland province for the periods 6 months prior to and 6 months following the introduction of the 'treat all' policy for people living with HIV infection. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact None as yet. This database was compiled by a PhD student. Papers are currently being drafted for publication. 
 
Title Methodology for spatial mapping 
Description Developed two new statistical approaches. One now underpins the local burden of disease project at IHME 
Type Of Material Computer model/algorithm 
Year Produced 2017 
Provided To Others? Yes  
Impact Model results used widely for policy. 
 
Title Molecular Markers of Anti-malaria Partner Drug Resistence 
Description Systematic review of mutations in Pfmdr1 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact None yet 
URL https://gh.bmj.com/content/3/5/e000999
 
Title Multi-locus negative frequency dependent selection model 
Description This model describes the multi-locus negative frequency dependent selection model of bacterial population evolution. 
Type Of Material Computer model/algorithm 
Year Produced 2017 
Provided To Others? Yes  
Impact This model was described in the original publication (Corander et al 2017 Nat. Ecol. Evol. 1:1950-1960), and has subsequently been used to optimise vaccine designs as a part of current work-in-progress. 
URL https://github.com/nickjcroucher/multilocusNFDS/
 
Title Research database on schistosomiasis and soil-transmitted helminthiases  
Description The schistosomiasis and soil-transmitted helminthiases (STHs) research theme aims to pool and make available Individual Patient Data (IPD) from all available studies to address knowledge gaps and improve treatment outcomes for people affected by these diseases. By amalgamating and standardising available individual patient data, the utility of existing resources can be maximised to address priority questions on the treatment of schistosomiasis and STHs, to create a framework to prospectively assemble future studies, to guide the design of future studies, and to make research progress more efficient. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact No impacts known yet 
URL https://www.iddo.org/research-themes/schistosomiasis-sths
 
Title Review of the effectiveness of indoor spraying of insecticide for control of malaria 
Description Systematic review of experimental hut trial data 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact Not known yet 
 
Title Serosolver R package 
Description This R package allows other scientists to investigate the life course of infection of an individual with influenza strains by using serological data from different historical strains gathered at different time points. 
Type Of Material Computer model/algorithm 
Year Produced 2020 
Provided To Others? Yes  
Impact It is being used by other members of the scientific community to support research 
URL https://github.com/seroanalytics/serosolver
 
Title Systematic collation of coronavirus cases Internationally and in mainland China 
Description Collation fo publically available data from government sources ad media to reconstruct linelist of cases for cases detected outside of China Daily updated case numbers across 33 provinces in China 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? No  
Impact Used in COVID-19 response and publciation in MRC reports. 
 
Title Systematic review of key parameters for the WHO R&D priority pathogens 
Description Systematic review of key parameters required for mathematical modelling and outbreak analytics for the 9 pathogens identified by WHO as high potential to cause epidemics. 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? No  
Impact Not yet recognised, though used to support COVID-19 analysis. 
 
Title Website for snakebite research (VenBank) 
Description Interactive web portal for global snakebite epidemiological study 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
Impact none yet (beta testing) 
URL https://venbank.info/
 
Title Within-host evolution model 
Description Compartmental model of within-host recombination between bacteria. 
Type Of Material Computer model/algorithm 
Year Produced 2016 
Provided To Others? Yes  
Impact This model was the basis of the publication Croucher et al. (2016) PLoS Biol. 14(3):e1002394. 
URL https://github.com/nickjcroucher/mgeTransformation
 
Description ALPHA Network 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of data from Manicaland, Zimbabwe for use in pooled and comparative analyses of trends and determinants of HIV incidence in sub-Saharan African countries with generalised epidemics in the post-antiretroviral treatment era. Contributions to analyses of the pooled and site-specific data.
Collaborator Contribution The ALPHA Network coordinated by researchers at the LSHTM sourced funding from BMGF for the project, are designing the data analyses to be conducted in the project, and will be organising data analysis workshops and results dissemination activities for the project.
Impact No outputs as yet
Start Year 2019
 
Description Alzheimers Disease Epidemiology Research Group (ADERG) 
Organisation Erasmus University Rotterdam
Country Netherlands 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities.
Impact Scientific publucations
Start Year 2017
 
Description Alzheimers Disease Epidemiology Research Group (ADERG) 
Organisation MRC Dementias Platform UK
Country United Kingdom 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities.
Impact Scientific publucations
Start Year 2017
 
Description Alzheimers Disease Epidemiology Research Group (ADERG) 
Organisation University of Gothenburg
Country Sweden 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities.
Impact Scientific publucations
Start Year 2017
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation Africa Health Research Institute
Country South Africa 
Sector Charity/Non Profit 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation Biomedical Research and Training Institute (BRTI)
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation Kenyan Institute for Medical Research (KEMRI)
Country Kenya 
Sector Public 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Department Alpha Network
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Department Department of Population Health
Country United Kingdom 
Sector Academic/University 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation MRC/UVRI Uganda Research Unit on AIDS
Country Uganda 
Sector Public 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation Rakai Health Sciences Program
Country Uganda 
Sector Public 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation University of the Witwatersrand
Country South Africa 
Sector Academic/University 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Avian influenza in wild african penguins 
Organisation University of Pretoria
Department Faculty of Veterinary Science
Country South Africa 
Sector Academic/University 
PI Contribution Statistical and epidemiological design, analysis and interpretation
Collaborator Contribution Provide veterinary expertise Data collection Diagnostic analysis Provide ecological expertise
Impact None reported yet
Start Year 2019
 
Description Baylor School of Medicine (Sasirekha Ramani) 
Organisation Baylor School
Country United States 
Sector Academic/University 
PI Contribution Lead coordinator on a study and design of clinical study design
Collaborator Contribution Rotavirus virology
Impact Not yet
Start Year 2016
 
Description Behaviour and bovine TB 
Organisation Cardiff University
Department School of Geography and Planning
Country United Kingdom 
Sector Academic/University 
PI Contribution Statistical analysis
Collaborator Contribution Behavioural science expertise
Impact Publication in Vaccine
Start Year 2019
 
Description Biomedical Research and Training Institute, Zimbawe 
Organisation Biomedical Research and Training Institute (BRTI)
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution Provide Analysis
Collaborator Contribution They provide fieldwork
Impact Awarded a grant with Simon Gregson: Multi-Level Behavioral Economics and Community Psychology Approaches to Strengthen HIV Prevention Cascades in Adolescent Girls and Young Women in East Zimbabwe.
Start Year 2017
 
Description Bristol University 
Organisation University of Bristol
Department Proteomics Facility
Country United Kingdom 
Sector Academic/University 
PI Contribution Modelling, data analysis
Collaborator Contribution Economic analysis and modelling. Supervision of researchers.
Impact Publications on the impact of the Avahan intervention in India. On-going HIV projects funded by linkages. A collaboration HSV 2 vaccination.
 
Description CDC Outbreak 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Developing rapid methodologies for analysis of fungal disease outbreaks
Collaborator Contribution Methodological and technological advances
Impact Ongoing manuscript preparation
Start Year 2014
 
Description Capacity building for research in conflict 
Organisation King's College London
Department Fondation Peters, King's College London
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Co-Principle Investigators on the project on capacity building for research in conflict.
Collaborator Contribution Co-Principle Investigators on the project on capacity building for research in conflict.
Impact Papers currently in draft.
Start Year 2018
 
Description Capacity building for research in conflict 
Organisation University of Cambridge
Department Cambridge Neuroscience
Country United Kingdom 
Sector Academic/University 
PI Contribution Co-Principle Investigators on the project on capacity building for research in conflict.
Collaborator Contribution Co-Principle Investigators on the project on capacity building for research in conflict.
Impact Papers currently in draft.
Start Year 2018
 
Description Central TB Division, Ministry of Health, Government of India 
Organisation Indian Ministry of Health
Country India 
Sector Public 
PI Contribution Ongoing work with Central TB Division to develop a modelling framework that can help them prioritise their TB control efforts across the country
Collaborator Contribution Developing the analytical framework in collaboration with national TB programme; coordinating with the programme to ensure that the model is maximally applicable; subcontracting additional analytical support from relevant experts in India
Impact Work ongoing
Start Year 2018
 
Description Centre for Infectious Disease Research Zambia 
Organisation Centre for Infectious Disease Research in Zambia
Country Zambia 
Sector Charity/Non Profit 
PI Contribution Study design and lab support for a rotavirus study
Collaborator Contribution Running a clinical trial of rotavirus vaccine in Zambia
Impact Successful application for "Human infection challenge vaccine (HIC-vac) network" with Roma Chilengi
Start Year 2018
 
Description Cervical Cancer Elimination 
Organisation Harvard University
Department Harvard Medical School
Country United States 
Sector Academic/University 
PI Contribution Mathematical modelling expertise and systematic reviews of epidemiological studies
Collaborator Contribution WHO - co-ordinating meetings and leading the initiative. Defining guidelines and co-ordinating media response Harvard University - Modelling analysis Laval - Modelling analysis and providing guidance McGill - Modelling analysis and providing guidance
Impact Numerous publications Informing WHO guidelines for cervical cancer elimination globally Media coverage
Start Year 2018
 
Description Cervical Cancer Elimination 
Organisation McGill University
Department Department of Epidemiology, Biostatistics and Occupational Health
Country Canada 
Sector Academic/University 
PI Contribution Mathematical modelling expertise and systematic reviews of epidemiological studies
Collaborator Contribution WHO - co-ordinating meetings and leading the initiative. Defining guidelines and co-ordinating media response Harvard University - Modelling analysis Laval - Modelling analysis and providing guidance McGill - Modelling analysis and providing guidance
Impact Numerous publications Informing WHO guidelines for cervical cancer elimination globally Media coverage
Start Year 2018
 
Description Cervical Cancer Elimination 
Organisation University Hospital of Laval University
Country Canada 
Sector Hospitals 
PI Contribution Mathematical modelling expertise and systematic reviews of epidemiological studies
Collaborator Contribution WHO - co-ordinating meetings and leading the initiative. Defining guidelines and co-ordinating media response Harvard University - Modelling analysis Laval - Modelling analysis and providing guidance McGill - Modelling analysis and providing guidance
Impact Numerous publications Informing WHO guidelines for cervical cancer elimination globally Media coverage
Start Year 2018
 
Description Cervical Cancer Elimination 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution Mathematical modelling expertise and systematic reviews of epidemiological studies
Collaborator Contribution WHO - co-ordinating meetings and leading the initiative. Defining guidelines and co-ordinating media response Harvard University - Modelling analysis Laval - Modelling analysis and providing guidance McGill - Modelling analysis and providing guidance
Impact Numerous publications Informing WHO guidelines for cervical cancer elimination globally Media coverage
Start Year 2018
 
Description Collaboration with Natashia Morris, Health GIS Centre, MRC South Africa 
Organisation Medical Research Council of South Africa (MRC)
Country South Africa 
Sector Public 
PI Contribution We have been in discussions with Dr Natashia Morris the Manager Health GIS Centre about how to determine whether a case of malaria identified by routine surveillance was contracted in country or imported from abroad. We have presented our methods and Dr Morris is looking to put into place systems which would allow the probability that a case of malaria was imported to be calculated instead of dichotomous decisions based on personal opinion.
Collaborator Contribution Provided information on data collected by the South African national malaria control programme and other countries in the E8 Partnership.
Impact None as yet.
Start Year 2018
 
Description Consolidated guidelines on HIV testing services for a changing epidemic 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution - Mathematical modelling of new algorithms and strategies for HIV diagnosis.
Collaborator Contribution - Technical leadership and oversight, production of normative guidance.
Impact - Revised 2019 WHO Consolidated Guidelines on HIV Testing Services - Policy brief: Consolidated guidelines on HIV testing services for a changing epidemic - Policy brief: WHO encourages countries to adapt HIV testing strategies in response to changing epidemic
Start Year 2018
 
Description Consultancy to develop guidelines for National Malaria Programmes for stratification, prioritisation and optimised resource allocation within strategic planning 
Organisation World Health Organization (WHO)
Department Global Malaria Programme
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution I am developing a document for National Malaria Programmes for stratification, prioritisation and optimised resource allocation within strategic planning as part of a wider drive to use routine malaria surveillance data for operational action.
Collaborator Contribution WHO is providing consultancy pay as well as general guidance and feedback
Impact No outputs to date.
Start Year 2019
 
Description DFID Ebola Situational Reports 
Organisation Government of the UK
Department Department for International Development (DfID)
Country United Kingdom 
Sector Public 
PI Contribution We have continued to share reports of the analysis of the ongoing Ebola outbreak in the Democratic Republic of the Congo. This has included projections of future incidence, bed demand, and vaccine demand estimates.
Collaborator Contribution Context for analysis needs e.g. requirements for vaccine demand.
Impact Reports for internal use at DFID and White Hall.
Start Year 2018
 
Description DeWorm3 
Organisation Natural History Museum
Country United Kingdom 
Sector Public 
PI Contribution Intellectual input, expertise and the training of staff.
Collaborator Contribution Intellectual input, expertise and the training of staff.
Impact Scientific journal publications in PLoS NTDs, Epidemics, Journal of Theoretical Biology, Lancet and Parasites and Vectors
Start Year 2016
 
Description DeWorm3 
Organisation University of Washington
Country United States 
Sector Academic/University 
PI Contribution Intellectual input, expertise and the training of staff.
Collaborator Contribution Intellectual input, expertise and the training of staff.
Impact Scientific journal publications in PLoS NTDs, Epidemics, Journal of Theoretical Biology, Lancet and Parasites and Vectors
Start Year 2016
 
Description Detection and Management of Ivermectin Resistance 
Organisation McGill University
Department Institute of Parasitology
Country Canada 
Sector Academic/University 
PI Contribution Mahematical modelling; preparation of papers; successful preparation of grant proposals
Collaborator Contribution Data on genetic analysis of filarial parasites (lymphatic filariasis, onchocerciasis) for mathematical modelling of the evolution and spread of anthelmintic resistance
Impact Outputs in the form of publications: PubMed ID numbers: 19805362; 19154624; 18382607; 17320006; 16834821. Outcomes in the form of invitations to speak at scientific meetings (Am Soc Trop Med Hyg, December 2008; Royal Society UK-Ghana collaboration, April 2008), and Expert Groups (WHO/World Bank, January 2008). Impacts in the form of invitation to belong to the Disease Reference Group on Helminths, World Health Organization.
 
Description Development of Clinical Trial Simulators for Macrofilaricidal Drugs for the Control of Filariases 
Organisation Drugs for Neglected Diseases initiative (DNDi)
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Development of clinical trial modelling simulators (paper in preparation)
Collaborator Contribution Meetings to discuss coordination of project
Impact Presentations to the Bill & Melinda Gates Foundation, American Society of Tropical Medicine and Hygiene, paper in preparation
Start Year 2016
 
Description Development of a viral kinetic model for Dengue infection 
Organisation Johnson & Johnson
Department Janssen Pharmaceuticals
Country United States 
Sector Private 
PI Contribution The aim of the Project is to develop a viral kinetics model for dengue infection in different species that enables evaluating the impact of a prophylactic intervention and/or therapeutic treatment on dengue infection. The goal is to build a viral kinetics model that has the potential to be translatable between species (mice - non-human primates (NHP) - human). The viral kinetics model will be used to gain more insight in the mechanism of action of the direct anti-viral drug candidates and to inform various stages of the drug development process, e.g. in determining different dosing regimens for upcoming studies. The hands-on modeling will be performed by an employee (post-doctoral research fellow) of the UNIVERSITY and a Global Clinical Pharmacology scientist of JANSSEN internally, under the supervision and scientific guidance from the Dengue development team, employees of Quantitative Sciences within JANSSEN, and appropriate representatives of the UNIVERSITY.
Collaborator Contribution The hands-on modeling will be performed by an employee (post-doctoral research fellow) of the UNIVERSITY and a Global Clinical Pharmacology scientist of JANSSEN internally, under the supervision and scientific guidance from the Dengue development team, employees of Quantitative Sciences within JANSSEN, and appropriate representatives of the UNIVERSITY.
Impact N/A at this stage.
Start Year 2019
 
Description District-level HIV estimation and HIV resource allocation in South Africa 
Organisation Government of South Africa
Department Department of Health
Country South Africa 
Sector Public 
PI Contribution - Statistical modelling of HIV surveillance and program data
Collaborator Contribution - Curation of survey and programme data. - Interpretation and implementation of estimates.
Impact - Official HIV estimates and targets for South Africa HIV programme
Start Year 2019
 
Description District-level HIV estimation and HIV resource allocation in South Africa 
Organisation Human Sciences Research Council (HSRC)
Country South Africa 
Sector Charity/Non Profit 
PI Contribution - Statistical modelling of HIV surveillance and program data
Collaborator Contribution - Curation of survey and programme data. - Interpretation and implementation of estimates.
Impact - Official HIV estimates and targets for South Africa HIV programme
Start Year 2019
 
Description District-level HIV estimation and HIV resource allocation in South Africa 
Organisation University of Cape Town
Country South Africa 
Sector Academic/University 
PI Contribution - Statistical modelling of HIV surveillance and program data
Collaborator Contribution - Curation of survey and programme data. - Interpretation and implementation of estimates.
Impact - Official HIV estimates and targets for South Africa HIV programme
Start Year 2019
 
Description District-level HIV estimation and HIV resource allocation in South Africa 
Organisation Wits Health Consortium
Country South Africa 
Sector Private 
PI Contribution - Statistical modelling of HIV surveillance and program data
Collaborator Contribution - Curation of survey and programme data. - Interpretation and implementation of estimates.
Impact - Official HIV estimates and targets for South Africa HIV programme
Start Year 2019
 
Description Dr. Kounbobr Roch Dabiré of IRSS (Burkina Faso) 
Organisation Research Institute for Health Sciences (IRSS)
Country Burkina Faso 
Sector Public 
PI Contribution We have provided training in the use of spectroscopy and the alalytical methods needed to interpret the results.
Collaborator Contribution Dr Dabiré leads a research team which is extending the methods we have developed to mosquito vectors of malaria in Africa.
Impact Project meeting in London (UK) and Bobo Dioulasso (Burkina Faso).
Start Year 2017
 
Description EIT Cross KIC Education 2018 - Challenge Based Learning 
Organisation Sorbonne University
Country France 
Sector Academic/University 
PI Contribution co-PI
Collaborator Contribution co-PIs
Impact Climate change and Health MOOC: https://www.futurelearn.com/courses/climate-change-public-health
Start Year 2018
 
Description EIT Cross KIC Education 2018 - Challenge Based Learning 
Organisation University of Grenoble
Country France 
Sector Academic/University 
PI Contribution co-PI
Collaborator Contribution co-PIs
Impact Climate change and Health MOOC: https://www.futurelearn.com/courses/climate-change-public-health
Start Year 2018
 
Description EIT Cross KIC Education 2018 - Challenge Based Learning 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution co-PI
Collaborator Contribution co-PIs
Impact Climate change and Health MOOC: https://www.futurelearn.com/courses/climate-change-public-health
Start Year 2018
 
Description Epidemiology and Control of Cystic Echinococcosis in Peru 
Organisation National University of Río Negro
Country Argentina 
Sector Academic/University 
PI Contribution Participation in and presentations at Newton Fund Workshop in Lima, September 2018 Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey
Collaborator Contribution Convening and organisation of Newton Fund Workshop Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey
Impact Multidisciplinary collaboration: epidemiologists, veterinarians, parasitologists, mathematical modellers
Start Year 2018
 
Description Epidemiology and Control of Cystic Echinococcosis in Peru 
Organisation National University of San Marcos
Country Peru 
Sector Academic/University 
PI Contribution Participation in and presentations at Newton Fund Workshop in Lima, September 2018 Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey
Collaborator Contribution Convening and organisation of Newton Fund Workshop Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey
Impact Multidisciplinary collaboration: epidemiologists, veterinarians, parasitologists, mathematical modellers
Start Year 2018
 
Description Epidemiology and Control of Cystic Echinococcosis in Peru 
Organisation University of Surrey
Country United Kingdom 
Sector Academic/University 
PI Contribution Participation in and presentations at Newton Fund Workshop in Lima, September 2018 Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey
Collaborator Contribution Convening and organisation of Newton Fund Workshop Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey
Impact Multidisciplinary collaboration: epidemiologists, veterinarians, parasitologists, mathematical modellers
Start Year 2018
 
Description Epidemiology and Control of Schistosomiasis and Soil-Transmitted Helminthiasis 
Organisation University of Cambridge
Department University of Cambridge, BBSRC IGF Drosophila Genomics Facility
Country United Kingdom 
Sector Academic/University 
PI Contribution Supervision of PhD students, in UK (together with the Schistosomiasis Control Initiative and the Royal Veterinary College) and Australia, for the analysis of data and preparation of joint publications
Collaborator Contribution Sharing of parasitological and epidemiological data pre- and post-implementation of control interventions based on anthelmintic chemotherapy in Africa for joint analysis through shared students
Impact Publications in peer-review journals
 
Description Epidemiology and Control of Schistosomiasis and Soil-Transmitted Helminthiasis 
Organisation University of Queensland
Department University of Queensland Diamantina Institute
Country Australia 
Sector Academic/University 
PI Contribution Supervision of PhD students, in UK (together with the Schistosomiasis Control Initiative and the Royal Veterinary College) and Australia, for the analysis of data and preparation of joint publications
Collaborator Contribution Sharing of parasitological and epidemiological data pre- and post-implementation of control interventions based on anthelmintic chemotherapy in Africa for joint analysis through shared students
Impact Publications in peer-review journals
 
Description Epidemiology and Control of Taeniasis/Cysticercosis 
Organisation Government of Madagascar
Country Madagascar 
Sector Public 
PI Contribution Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts
Collaborator Contribution Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030.
Impact Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports
Start Year 2017
 
Description Epidemiology and Control of Taeniasis/Cysticercosis 
Organisation Imperial College London
Department Schistosomiasis Control Initiative (SCI)
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts
Collaborator Contribution Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030.
Impact Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports
Start Year 2017
 
Description Epidemiology and Control of Taeniasis/Cysticercosis 
Organisation Institute of Tropical Medicine Antwerp
Country Belgium 
Sector Academic/University 
PI Contribution Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts
Collaborator Contribution Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030.
Impact Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports
Start Year 2017
 
Description Epidemiology and Control of Taeniasis/Cysticercosis 
Organisation Royal Veterinary College (RVC)
Country United Kingdom 
Sector Academic/University 
PI Contribution Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts
Collaborator Contribution Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030.
Impact Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports
Start Year 2017
 
Description Epidemiology and Control of Taeniasis/Cysticercosis 
Organisation Technical University of Munich
Country Germany 
Sector Academic/University 
PI Contribution Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts
Collaborator Contribution Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030.
Impact Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports
Start Year 2017
 
Description Epidemiology and Control of Taeniasis/Cysticercosis 
Organisation The Statens Serum Institute (SSI)
Country Denmark 
Sector Public 
PI Contribution Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts
Collaborator Contribution Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030.
Impact Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports
Start Year 2017
 
Description Epidemiology and Control of Taeniasis/Cysticercosis 
Organisation University of Ghent
Country Belgium 
Sector Academic/University 
PI Contribution Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts
Collaborator Contribution Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030.
Impact Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports
Start Year 2017
 
Description Epidemiology of Onchocerciasis and Loiasis in Central Africa 
Organisation University of Montpellier
Country France 
Sector Academic/University 
PI Contribution Preparation of joint publications and research proposals that have been successfully funded (e.g. Royal Society)
Collaborator Contribution Sharing of data for joint analysis of parasitological and epidemiological features of infections caused by Onchocerca volvulus and Loa loa
Impact Publications in peer-review journals; reports for World Health Organization (on Alternative Treatment Strategies for onchocerciasis). See also presence in London Centre for Neglected Tropical Disease Research: https://www.londonntd.org/research/projects-search/developing-models-of-loiasis-transmission-to-inform-control-of-the-disease
 
Description Epidemiology of Onchocerciasis and Loiasis in Central Africa 
Organisation University of Yaoundé
Country Cameroon 
Sector Academic/University 
PI Contribution Preparation of joint publications and research proposals that have been successfully funded (e.g. Royal Society)
Collaborator Contribution Sharing of data for joint analysis of parasitological and epidemiological features of infections caused by Onchocerca volvulus and Loa loa
Impact Publications in peer-review journals; reports for World Health Organization (on Alternative Treatment Strategies for onchocerciasis). See also presence in London Centre for Neglected Tropical Disease Research: https://www.londonntd.org/research/projects-search/developing-models-of-loiasis-transmission-to-inform-control-of-the-disease
 
Description Ethics in universal health coverage 
Organisation University of Stellenbosch
Country South Africa 
Sector Academic/University 
PI Contribution Principle investigator for the research project on ethics in universal health coverage.
Collaborator Contribution Co-principle investigator for the research project on ethics in universal health coverage.
Impact Conference presentations, publications in process.
Start Year 2018
 
Description Ethics in universal health coverage 
Organisation University of the Witwatersrand
Department Wits Reproductive Health and HIV Institute
Country South Africa 
Sector Academic/University 
PI Contribution Principle investigator for the research project on ethics in universal health coverage.
Collaborator Contribution Co-principle investigator for the research project on ethics in universal health coverage.
Impact Conference presentations, publications in process.
Start Year 2018
 
Description Floyd Dowell of United States Department of Agriculture 
Organisation U.S. Department of Agriculture USDA
Department Agricultural Research Service
Country United States 
Sector Public 
PI Contribution We have developed new analytical methods to understand how mosquito age, species and infection status (with the malaria parasite) changes the light being measured by a spectrometer
Collaborator Contribution Dr Dowell is a Research Agricultural Engineer who has pioneered work using Near Infrared Spectroscopy to investigate the age of mosquitoes. Dr Dowell provided training and technical advice to scientists from Imperial College London and our partners
Impact Training of UK, Burkinabe and Australian Scientists in the use of spectrometer
Start Year 2017
 
Description FluScape 
Organisation Johns Hopkins University
Department Johns Hopkins Bloomberg School of Public Health
Country United States 
Sector Academic/University 
PI Contribution We run an epidemiological study in Southern China. At imperial we manage the field site and conduct mathematical and statistical analysis.
Collaborator Contribution Johns Hopkins manage the information systems and also conduct mathematical and statistical analysis.
Impact Any paper with Cummings as a co-author.
Start Year 2008
 
Description Foundation for Innovative New Diagnostics 
Organisation Foundation for Innovative New Diagnostics (FIND)
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Contributing modelling analysis in support of WHO recommendations for new diagnostic tools for tuberculosis
Collaborator Contribution Developing a modelling framework to project the potential impact of new diagnostic tools being supported by FIND, on the TB epidemic in settings such as South Africa. The work will be used to inform new WHO guidelines.
Impact Work ongoing
Start Year 2018
 
Description Future preventive therapy regimens for TB 
Organisation Aurum Institute
Country South Africa 
Sector Public 
PI Contribution Modelling analysis in support of new WHO guidelines for target profiles of future regimens
Collaborator Contribution Providing data and inputs for the modelling
Impact New target product profiles from WHO currently in preparation - will incorporate modelling Manuscript pending
Start Year 2019
 
Description Future preventive therapy regimens for TB 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution Modelling analysis in support of new WHO guidelines for target profiles of future regimens
Collaborator Contribution Providing data and inputs for the modelling
Impact New target product profiles from WHO currently in preparation - will incorporate modelling Manuscript pending
Start Year 2019
 
Description Gagandeep Kang-Christian Medical College 
Organisation Christian Medical College, Vellore
Country India 
Sector Academic/University 
PI Contribution Gastrointestinal Sciences. Statistical, epidemiological and mathematical analysis
Collaborator Contribution Clinical studies, immunological analysis
Impact multiple publications, grant renewal in 2020
Start Year 2010
 
Description Geshiaro 
Organisation Ethiopian Public Health Institute
Country Ethiopia 
Sector Public 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities
Impact No outputs yet.
Start Year 2018
 
Description Geshiaro 
Organisation Ministry of Health, Ethiopia
Country Ethiopia 
Sector Public 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities
Impact No outputs yet.
Start Year 2018
 
Description Geshiaro 
Organisation Simprints
Country United Kingdom 
Sector Public 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities
Impact No outputs yet.
Start Year 2018
 
Description Geshiaro 
Organisation World Vision Ethiopia
Country Ethiopia 
Sector Public 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities
Impact No outputs yet.
Start Year 2018
 
Description Geshiyaro project (clinical trial) 
Organisation Ethiopian Public Health Institute
Country Ethiopia 
Sector Public 
PI Contribution Design of trial Monitoring and evaluation of progress
Collaborator Contribution Implementers of NTD treatments Partners in Monitoring and Evaluation
Impact Publication on protocol of trial in 'Parasites and Vectors' in October 2019
Start Year 2019
 
Description Global Burden of disease 
Organisation Institute for Health Metrics and Evaluation (IHME)
Country United States 
Sector Charity/Non Profit 
PI Contribution Provided algorithms for the local burden of disease project
Collaborator Contribution Publications (3 in nature 1 in the New England Journal of Medicine, 1 in Lancet)
Impact Publications (3 in nature 1 in the New England Journal of Medicine, 1 in Lancet)
Start Year 2016
 
Description Greg Devine at QIMR Berghofer (Brisbane, Australia) 
Organisation QIMR Berghofer Medical Research Institute
Country Australia 
Sector Academic/University 
PI Contribution Provide funding to run experiments in Australia on local Aedes mosquito populations
Collaborator Contribution Partner running experiments in Australia on local Aedes mosquito populations
Impact None yet
Start Year 2017
 
Description HIV DREAMS evaluation 
Organisation United States Department of State
Department Office of the Global AIDS Coordinator
Country United States 
Sector Public 
PI Contribution Samir Bhatt's group worked with OGAC to estimate the rate of change of new diagnoses among pregnant women.
Collaborator Contribution Technical expertise in data preparation
Impact Samir Bhatt produced the modelled estimates that were used by OGAC in their world AIDS day report. The announcement was made by Amb Birx in December 2019.
Start Year 2016
 
Description HIV Preventation Trial Network 
Organisation Fred Hutchinson Cancer Research Center (FHCRC)
Country United States 
Sector Charity/Non Profit 
PI Contribution A collaborative centre that develops and uses mathematical models to support HPTN research activities and inform research directions. We collaborate with: Statistical Centre for HIV/AIDS Research and Prevention.
Collaborator Contribution See above
Impact See publications, presentations and workshops on https://hptnmodelling.org/resources/
Start Year 2014
 
Description HIV Prevention Trial Network Modelling Centre 
Organisation Fred Hutchinson Cancer Research Center (FHCRC)
Country United States 
Sector Charity/Non Profit 
PI Contribution Lead on Mathematical modelling to inform and complement research activities of the HPTN. Conduct mathematical modelling and computer simulation studies anchored to the best available data to support and inform HPTN research activities and directions with the overarching aim to combat the HIV/AIDS epidemic more efficiently
Collaborator Contribution Lead of statistical centre who is funding the HPTN modelling centre. Provide data and statistical expertise, conduct trials that provide data for mathematical modelling.
Impact A number of publications: https://hptnmodelling.org/resources/?resourcetype=publications Multidisciplinary - epidemiology, mathematical modelling, statistics, clinical research
Start Year 2013
 
Description HIV prevention cascades 
Organisation Bill and Melinda Gates Foundation
Country United States 
Sector Charity/Non Profit 
PI Contribution Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications.
Collaborator Contribution The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas.
Impact UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health
Start Year 2015
 
Description HIV prevention cascades 
Organisation Biomedical Research and Training Institute (BRTI)
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications.
Collaborator Contribution The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas.
Impact UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health
Start Year 2015
 
Description HIV prevention cascades 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS)
Country Global 
Sector Public 
PI Contribution Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications.
Collaborator Contribution The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas.
Impact UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health
Start Year 2015
 
Description HIV prevention cascades 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications.
Collaborator Contribution The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas.
Impact UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health
Start Year 2015
 
Description HIV prevention cascades 
Organisation Ministry of Health and Child Welfare of the Republic of Zimbabwe
Country Zimbabwe 
Sector Public 
PI Contribution Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications.
Collaborator Contribution The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas.
Impact UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health
Start Year 2015
 
Description HIV prevention cascades 
Organisation Population Services International
Country United States 
Sector Charity/Non Profit 
PI Contribution Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications.
Collaborator Contribution The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas.
Impact UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health
Start Year 2015
 
Description HIV rapid test misclassification errors 
Organisation Biomedical Research and Training Institute (BRTI)
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing.
Collaborator Contribution The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study
Impact Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology
Start Year 2015
 
Description HIV rapid test misclassification errors 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing.
Collaborator Contribution The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study
Impact Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology
Start Year 2015
 
Description HIV rapid test misclassification errors 
Organisation Global Solutions for Infectious Disease
Country United States 
Sector Charity/Non Profit 
PI Contribution Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing.
Collaborator Contribution The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study
Impact Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology
Start Year 2015
 
Description HIV rapid test misclassification errors 
Organisation Ministry of Health and Child Welfare of the Republic of Zimbabwe
Country Zimbabwe 
Sector Public 
PI Contribution Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing.
Collaborator Contribution The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study
Impact Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology
Start Year 2015
 
Description HIV rapid test misclassification errors 
Organisation Roehampton University
Country United Kingdom 
Sector Academic/University 
PI Contribution Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing.
Collaborator Contribution The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study
Impact Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology
Start Year 2015
 
Description HIV rapid test misclassification errors 
Organisation University of Copenhagen
Department Department of Public Health
Country Denmark 
Sector Academic/University 
PI Contribution Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing.
Collaborator Contribution The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study
Impact Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology
Start Year 2015
 
Description HPRU Modelling 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution I am a theme lead for the HPRU in Modelling Methodology held by Neil Ferguson.
Collaborator Contribution Marc Baguelin (co-I for this MRC grant) is also a theme lead.
Impact None yet.
Start Year 2014
 
Description HPRU Respiratory Infections 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution I am a theme lead for Respiratory infections and will help to supervise staff at Imperial and PHE.
Collaborator Contribution They will also co supervise staff and helped to write the grant.
Impact None yet.
Start Year 2014
 
Description HSV2 vaccine 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS)
Country Global 
Sector Public 
PI Contribution Mathematical Modelling expertise and modelling analysis
Collaborator Contribution Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews
Impact Publications to come
Start Year 2019
 
Description HSV2 vaccine 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Mathematical Modelling expertise and modelling analysis
Collaborator Contribution Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews
Impact Publications to come
Start Year 2019
 
Description HSV2 vaccine 
Organisation Oswaldo Cruz Foundation (Fiocruz)
Country Brazil 
Sector Public 
PI Contribution Mathematical Modelling expertise and modelling analysis
Collaborator Contribution Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews
Impact Publications to come
Start Year 2019
 
Description HSV2 vaccine 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Mathematical Modelling expertise and modelling analysis
Collaborator Contribution Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews
Impact Publications to come
Start Year 2019
 
Description HSV2 vaccine 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution Mathematical Modelling expertise and modelling analysis
Collaborator Contribution Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews
Impact Publications to come
Start Year 2019
 
Description How can modelling contribute to achieving the goals for Chagas disease in the horizon 2020 and beyond? 
Organisation Pan American Health Organization
Country United States 
Sector Charity/Non Profit 
PI Contribution Development of a data platform for collation and curation of Chagas disease epidemiological data Development of force of infection models for Chagas disease Contribution to papers on Chagas disease modelling
Collaborator Contribution Princeton: Contribution of expertise in mathematical modelling Sussex: Contribution of machine learning methods PAHO: Funding of in country workshops and person based in Washington dedicated to systematic reviews, data entry and liaising with endemic countries
Impact Publication of papers in Clinical Infectious Diseases, BMJ Global Health Attendance to WHO meeting in Geneva in April 2019 to help assess through modelling, the feasibility of the WHO proposed goals for Chagas disease, 2021- 2030 Preparation of a Gates Open Research open letter
Start Year 2018
 
Description How can modelling contribute to achieving the goals for Chagas disease in the horizon 2020 and beyond? 
Organisation Princeton University
Country United States 
Sector Academic/University 
PI Contribution Development of a data platform for collation and curation of Chagas disease epidemiological data Development of force of infection models for Chagas disease Contribution to papers on Chagas disease modelling
Collaborator Contribution Princeton: Contribution of expertise in mathematical modelling Sussex: Contribution of machine learning methods PAHO: Funding of in country workshops and person based in Washington dedicated to systematic reviews, data entry and liaising with endemic countries
Impact Publication of papers in Clinical Infectious Diseases, BMJ Global Health Attendance to WHO meeting in Geneva in April 2019 to help assess through modelling, the feasibility of the WHO proposed goals for Chagas disease, 2021- 2030 Preparation of a Gates Open Research open letter
Start Year 2018
 
Description How can modelling contribute to achieving the goals for Chagas disease in the horizon 2020 and beyond? 
Organisation University of Sussex
Country United Kingdom 
Sector Academic/University 
PI Contribution Development of a data platform for collation and curation of Chagas disease epidemiological data Development of force of infection models for Chagas disease Contribution to papers on Chagas disease modelling
Collaborator Contribution Princeton: Contribution of expertise in mathematical modelling Sussex: Contribution of machine learning methods PAHO: Funding of in country workshops and person based in Washington dedicated to systematic reviews, data entry and liaising with endemic countries
Impact Publication of papers in Clinical Infectious Diseases, BMJ Global Health Attendance to WHO meeting in Geneva in April 2019 to help assess through modelling, the feasibility of the WHO proposed goals for Chagas disease, 2021- 2030 Preparation of a Gates Open Research open letter
Start Year 2018
 
Description IMPPACT: Maximising the public health impact of interventions to control malaria in pregnancy 
Organisation Liverpool School of Tropical Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution To generate modelling and mapping of optimal preventative strategies for the prevention of malaria in pregnancy. These results were presented at Regional meetings of national policymakers in West and East Africa in Togo and Kenya respectively.
Collaborator Contribution Other partners were responsible for organising meetings, developing stakeholder interviews and translating results from recent trials into other policy-relevant recommendations and outputs.
Impact Multi-disciplinary: Modelling, Qualitative and Quantitive research, health economics and policy-making Regional meetings in Togo and Kenya Publication in PLoS Medicine and further publication pending.
Start Year 2015
 
Description IMPPACT: Maximising the public health impact of interventions to control malaria in pregnancy 
Organisation Sixth Framework Programme (FP6)
Department European and Developing Countries Clinical Trials Partnership
Country Netherlands 
Sector Public 
PI Contribution To generate modelling and mapping of optimal preventative strategies for the prevention of malaria in pregnancy. These results were presented at Regional meetings of national policymakers in West and East Africa in Togo and Kenya respectively.
Collaborator Contribution Other partners were responsible for organising meetings, developing stakeholder interviews and translating results from recent trials into other policy-relevant recommendations and outputs.
Impact Multi-disciplinary: Modelling, Qualitative and Quantitive research, health economics and policy-making Regional meetings in Togo and Kenya Publication in PLoS Medicine and further publication pending.
Start Year 2015
 
Description Information on a novel malaria transmission blocking vaccine candidate 
Organisation National Institutes of Health (NIH)
Department Vaccine Research Center (VRC)
Country United States 
Sector Public 
PI Contribution We are using mathematical models to predict the effectiveness of a novel vaccine candidate when used in a small scale field trial and in a wider mass distribution campaign.
Collaborator Contribution Provide details on the vaccine candidate including its efficacy and duration of protection.
Impact Predictive models that can support sample size calculations to adequately power studies.
Start Year 2019
 
Description Integrating genomic surveillance and ecological modelling to maximise pneumococcal vaccine efficacy 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Providing expertise in mathematical modelling and genomic epidemiology.
Collaborator Contribution Genome sequencing, sharing of data and expertise in epidemiology and vaccinology.
Impact No outputs yet.
Start Year 2019
 
Description Javier Martin (Dr) -NIBSC 
Organisation National Institute for Biological Standards and Control (NIBSC)
Country United Kingdom 
Sector Public 
PI Contribution Sequencing and analysis of polio virus in environmental samples
Collaborator Contribution Virus isolation and sequencing
Impact A supplement to the existing grant and a new grant
Start Year 2017
 
Description Jinan University 
Organisation Jinan University
Country China 
Sector Academic/University 
PI Contribution We will provide samples and analysis and Jinan will conduct immunological assays
Collaborator Contribution We will provide samples and analysis and Jinan will conduct immunological assays
Impact None yet
Start Year 2016
 
Description Kenya National Aid Control Council - Dr Nduku Kilonzo - Preparing for the double burden HIV 
Organisation Kenya National Malaria Control Programme
Country Kenya 
Sector Public 
PI Contribution Tim Hallett leads the research to inform policy
Collaborator Contribution Partners run the programme in Kenya
Impact A grant was obtained in 2017 and it is still active. Publication of 2 manuscripts in BMJ Global Health and CID
Start Year 2014
 
Description Laval University 
Organisation University Hospital of Laval University
Country Canada 
Sector Hospitals 
PI Contribution Collaborating with two teams lead by Michel Alary (HIV) and Marc Brisson (HPV Vaccination). I provide expetise in Modelling Statistical Analysis and Epidemiological expertise at the intersection between HIV and HPV.
Collaborator Contribution Michel Alary provides the epidemiological expertise and Marc Brisson provides modelling in health economic expertise.
Impact Multiple Publications and successful grant applications.
 
Description London Centre for NTD Research 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Collaborator Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Impact Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations.
Start Year 2013
 
Description London Centre for NTD Research 
Organisation Natural History Museum
Country United Kingdom 
Sector Public 
PI Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Collaborator Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Impact Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations.
Start Year 2013
 
Description London Centre for NTD Research 
Organisation Royal Veterinary College (RVC)
Country United Kingdom 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Collaborator Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Impact Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations.
Start Year 2013
 
Description London Centre for NTD Research 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Collaborator Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Impact Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations.
Start Year 2013
 
Description MIT Broad Institute 
Organisation Broad Institute
Country United States 
Sector Charity/Non Profit 
PI Contribution Contribution of whole genome sequences of Cryptococcus neoformans, analysis and experimental data
Collaborator Contribution Contribution of whole genome sequences of Cryptococcus neoformans and analysis.
Impact Paper in submission
Start Year 2012
 
Description MRC Centre for Global Health Analysis - "Breaking silos and building collaborations for integrated and sustainable management of cholangiocarcinoma and its causal pathogen Opisthorchis viverrini in LMICs in the Lower Mekong Region 
Organisation Global Health Asia Institute
Country Thailand 
Sector Charity/Non Profit 
PI Contribution PI
Collaborator Contribution co-I
Impact none yet
Start Year 2018
 
Description MRC Centre for Global Health Analysis - "Breaking silos and building collaborations for integrated and sustainable management of cholangiocarcinoma and its causal pathogen Opisthorchis viverrini in LMICs in the Lower Mekong Region 
Organisation International Agency for Research on Cancer (IARC)
Country France 
Sector Academic/University 
PI Contribution PI
Collaborator Contribution co-I
Impact none yet
Start Year 2018
 
Description MRC Centre for Global Health Analysis - "Breaking silos and building collaborations for integrated and sustainable management of cholangiocarcinoma and its causal pathogen Opisthorchis viverrini in LMICs in the Lower Mekong Region 
Organisation Phramongkutklao College of Medicine
Country Thailand 
Sector Academic/University 
PI Contribution PI
Collaborator Contribution co-I
Impact none yet
Start Year 2018
 
Description MRC Dementias Collaboration 
Organisation MRC Dementias Platform UK
Country United Kingdom 
Sector Academic/University 
PI Contribution Creation of clinical trial simulator for possible therapies for Alzheimer's New methods for analysis of epidemiological data for Alzheimer's disease progression
Collaborator Contribution Clincial, Statistical and Epidemiological input
Impact Publications in scientific journals
Start Year 2019
 
Description Malaria in Pregnancy 
Organisation Liverpool School of Tropical Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution This collaboration involves estimating the burden of malaria in pregnancy, its relationship with transmission and the impact of interventions. I provide mathematical modelling expertise, data analysis to questions relevant to these issues.
Collaborator Contribution Members of the Malaria in Pregnancy Consortium Secretariat provide support for these analyses in terms of providing access to data and academic support and input. As well as providing funding for travel to meetings.
Impact I developed the first model of malaria in pregnancy (Walker et al, Nature Communications 2012) and its link to transmission and using this was able to develop the first map of potential low birth weight burden attributable to malaria (Walker et al, Lancet Global Health 2014). I am also part of a working group looking at the incremental impact of switching to a policy of testing pregnant women for malaria and treating them if infected (Incremental Screening and Treatment) relative to treating them presumptively which will provide scientific support to an Evidence Review Group which will report to the Malaria Policy Advisory Committee of the World Health Organisation about the potential area of application of this strategy. I provided a preliminary version of this analysis during a Malaria in Pregnancy symposium at ASTMH 2014 in New Orleans. Research from this collaboration was also presented at the Evidence Review Group meeting into Intermittent screening and treatment in pregnancy and the safety of ACTs in the first trimester at WHO in Geneva in July 2015 and had direct influence on WHO malaria in pregnancy policy.
Start Year 2014
 
Description Malaria mapping and burden 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution I provided supervision and worked collaboratively to produce malaria estimates for the global burden of disease project, the WHO and the global fund.
Collaborator Contribution Two subcontract grants, computational facilities, data preparation and synthesis, facility space at the Big data institute
Impact 2 papers submitted to the Lancet, 1 paper accepted in Nature
Start Year 2016
 
Description Malaria project collaborations 
Organisation Government of The Gambia
Country Gambia 
Sector Public 
PI Contribution Guide economic work packages
Collaborator Contribution co-production of research questions, data collection, analysis and dissemination
Impact Papers in press and preparation
 
Description Malaria project collaborations 
Organisation MURAZ Center
Country Burkina Faso 
Sector Academic/University 
PI Contribution Guide economic work packages
Collaborator Contribution co-production of research questions, data collection, analysis and dissemination
Impact Papers in press and preparation
 
Description Malaria project collaborations 
Organisation Medical Research Council (MRC)
Department MRC Unit, The Gambia
Country Gambia 
Sector Public 
PI Contribution Guide economic work packages
Collaborator Contribution co-production of research questions, data collection, analysis and dissemination
Impact Papers in press and preparation
 
Description Malaria project collaborations 
Organisation University of Bamako
Country Mali 
Sector Academic/University 
PI Contribution Guide economic work packages
Collaborator Contribution co-production of research questions, data collection, analysis and dissemination
Impact Papers in press and preparation
 
Description Malawi Public Health Institute 
Organisation Public Health Institute of Malawi
Country Malawi 
Sector Public 
PI Contribution Analysis of data
Collaborator Contribution Collation of data
Impact Nothing to report
Start Year 2018
 
Description Malawi/Kenya 
Organisation Wellcome Trust
Department Malawi-Liverpool Wellcome Trust Clinical Research Programme
Country Malawi 
Sector Academic/University 
PI Contribution I recruited a Research Assistant from Malawi, on a UK Royal Society Global Challenges grant, in June 2017 to undertake modelling of the impact of intermittent treatment in pregnancy for malaria on drug resistance development. He worked for a year and a half working with me training in mathematical modelling.
Collaborator Contribution The partner hosted our postdoc for a number of months in Malawi, provided supervision and regular phone calls to discuss the progress of the project. They are also currently undertaking large trials of intermittent preventive treatment in pregnant women, and these trials helped to inform our modelling analysis.
Impact The RA recruited has now gone on to a PhD to LSHTM in the same field, which we hope will contribute to capacity building.
Start Year 2016
 
Description Mapping housing quality 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution A collaborative project mapping housing quality in Africa
Collaborator Contribution Research support, data assistance
Impact 1 paper accepted in Nature (article)
Start Year 2018
 
Description Mapping the risk of international infectious disease spread 
Organisation HealthMap
Sector Charity/Non Profit 
PI Contribution Developing a mathematical model of spatial spread of infectious diseases
Collaborator Contribution Providing data on Ebola
Impact Talks at several conferences Papers in preparation
Start Year 2016
 
Description Mapping the risk of international infectious disease spread 
Organisation Healthsites.io
Country France 
Sector Private 
PI Contribution Developing a mathematical model of spatial spread of infectious diseases
Collaborator Contribution Providing data on Ebola
Impact Talks at several conferences Papers in preparation
Start Year 2016
 
Description Mapping the risk of international infectious disease spread 
Organisation International Society for Infectious Diseases (ISID)
Department Program for Monitoring Emerging Diseases
Country United States 
Sector Charity/Non Profit 
PI Contribution Developing a mathematical model of spatial spread of infectious diseases
Collaborator Contribution Providing data on Ebola
Impact Talks at several conferences Papers in preparation
Start Year 2016
 
Description Mapping the risk of international infectious disease spread 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Developing a mathematical model of spatial spread of infectious diseases
Collaborator Contribution Providing data on Ebola
Impact Talks at several conferences Papers in preparation
Start Year 2016
 
Description Medicines for Malaria Venture 
Organisation Medicines for Malaria Venture (MMV)
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution We are using mathematical modelling to estimate the impact of both existing antimalarial drugs and also products in development on malaria transmission, and their cost-effectiveness.
Collaborator Contribution Funding (research costs and 1 postdoc for 3 years), requests for research and advice on ongoing work.
Impact A data collaboration with the Worldwide Antimalarial Resistance Network and Sanofi Ltd to access clinical trial data. We published three papers: Nature Communications (2017), Malaria Journal (2017) and Trends in Parasitology (2017).
Start Year 2013
 
Description Member of Malaria Modelling Consortium 
Organisation Bill and Melinda Gates Foundation
Country United States 
Sector Charity/Non Profit 
PI Contribution I participated in consortium meetings, and contributed substantially to a Malaria Modelling Consortium report to the World Health Organization Malaria Policy Advisory Group on results from modelling mass drug administration for malaria control.
Collaborator Contribution Other modelling partners contribute modelling results, the Gates Foundation coordinate activities, arrange meetings and fund travel for the meetings.
Impact Malaria Modelling Consortium report to the World Health Organization Malaria Policy Advisory Group on results from modelling mass drug administration for malaria control. This is now published as a paper in Lancet Global Health.
Start Year 2015
 
Description Memorandum of Understanding with National Institute of Health - Colombia 
Organisation Government of Colombia
Department National Institute of Health, Colombia
Country Colombia 
Sector Public 
PI Contribution Cooperative working and exchange of research in public health and education activities in science and technology. Overseeing study design, data analysis and write-up.
Collaborator Contribution Cooperative working and exchange of research in public health and education activities in science and technology. Data sharing.
Impact Kelly Charniga (PhD) funded by Imperial President Scholarship
Start Year 2017
 
Description Miren Iturizza-Gomara (Prof-Mrs) University of Liverpool 
Organisation University of Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution Microbiome analysis
Collaborator Contribution Provide rotavirus
Impact 1 publication BMJ Open
Start Year 2018
 
Description Modelling West Nile Virus in Italy 
Organisation Edmund Mach Foundation
Country Italy 
Sector Charity/Non Profit 
PI Contribution Mathematical modelling expertise
Collaborator Contribution Provision of data Mathematical modelling expertise
Impact 1 paper published in PLoS NTDs and one manuscript under review Conference presentations
Start Year 2018
 
Description Modelling West Nile Virus in Italy 
Organisation Experimental Zooprophylactic Institute of the Venezie
Country Italy 
Sector Public 
PI Contribution Mathematical modelling expertise
Collaborator Contribution Provision of data Mathematical modelling expertise
Impact 1 paper published in PLoS NTDs and one manuscript under review Conference presentations
Start Year 2018
 
Description Modelling West Nile Virus in Italy 
Organisation Pasteur Institute, Paris
Country France 
Sector Charity/Non Profit 
PI Contribution Mathematical modelling expertise
Collaborator Contribution Provision of data Mathematical modelling expertise
Impact 1 paper published in PLoS NTDs and one manuscript under review Conference presentations
Start Year 2018
 
Description Modelling West Nile Virus in Italy 
Organisation University of Trento
Country Italy 
Sector Academic/University 
PI Contribution Mathematical modelling expertise
Collaborator Contribution Provision of data Mathematical modelling expertise
Impact 1 paper published in PLoS NTDs and one manuscript under review Conference presentations
Start Year 2018
 
Description Modelling and dengue vaccines 
Organisation Takeda Pharmaceutical Company
Department Takeda Global Research & Development Centre (Europe)
Country United Kingdom 
Sector Private 
PI Contribution Modelling related to Dengue disease and vaccination.
Collaborator Contribution Know how with regard to its therapeutic area vaccines and in particular, but limited to its Dengue, Norovirus and Polio candidate vaccines.
Impact N?A at this stage.
Start Year 2018
 
Description Modelling dengue vaccination 
Organisation Sanofi
Department Sanofi Research Division
Country France 
Sector Private 
PI Contribution Mathematical modelling of immunogenicity and efficacy data
Collaborator Contribution Provision of data Contribution to mathematical modelling
Impact Publication of several papers Talks at numerous conferences
Start Year 2013
 
Description Modelling pandemic influenza in the USA 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Building model of pandemic influenza in USA to support CDC planning
Collaborator Contribution Providing data and convening network of modelling
Impact Ongoing
Start Year 2019
 
Description Modelling the elimination of onchocerciasis in Cameroon 
Organisation Royal Veterinary College (RVC)
Country United Kingdom 
Sector Academic/University 
PI Contribution Joint publication in Systematic Reviews Mentoring of a PhD student from Cameroon through AIMS Cameroon for mathematical modelling Provide the mathematical and geostatistical modelling expertise
Collaborator Contribution Responsible for collating and curating the data Drafting of manuscript for publication
Impact Mentoring of a PhD student and modelling outcomes that will help the MoH in Cameroon to identify optimal interventions for onchocerciasis elimination
Start Year 2018
 
Description Modelling the elimination of onchocerciasis in Cameroon 
Organisation University of Yaoundé
Country Cameroon 
Sector Academic/University 
PI Contribution Joint publication in Systematic Reviews Mentoring of a PhD student from Cameroon through AIMS Cameroon for mathematical modelling Provide the mathematical and geostatistical modelling expertise
Collaborator Contribution Responsible for collating and curating the data Drafting of manuscript for publication
Impact Mentoring of a PhD student and modelling outcomes that will help the MoH in Cameroon to identify optimal interventions for onchocerciasis elimination
Start Year 2018
 
Description Modelling the epidemiological impact of moxidectin for the control and elimination of onchocerciasis 
Organisation Medicines Development for Global Health
Country Australia 
Sector Private 
PI Contribution Providing modelling simulations to assess the probabilities of elimination in policy relevant settings. Preparation of joint publications and posters
Collaborator Contribution Provision of phase III clinical trial data for model parameterisation Provision of input throughout the collaboration
Impact Preparation of FDA dossier for approval of moxidectin for human use
Start Year 2017
 
Description Modelling to support Kenya's National Strategic Plan for TB control 
Organisation Ministry of Health, Kenya
Country Kenya 
Sector Public 
PI Contribution Providing analysis and modelling in support of Kenya's upcoming National Strategic Plan for TB control
Collaborator Contribution Kenya's new national strategic plan will be used as a model by funding agencies such as the Global Fund, for applications by other countries. The modelling component of the strategic plan plays a key role in prioritisation amongst different interventions, and the Global Fund and other donors will require that other future applications are structured in the same way.
Impact Modelling input into National Strategic Plan, to be launched on World TB Day (24 Mar 2019) Work ongoing
Start Year 2017
 
Description Modelling within host kinetics of dengue 
Organisation Janssen Pharmaceutica NV
Country Belgium 
Sector Private 
PI Contribution Mathematical modelling expertise
Collaborator Contribution Provision of data Contribution to modelling
Impact Not yet recognised - collaboration ongoing
Start Year 2019
 
Description NHIR emergency room demand 
Organisation Imperial College London
Department NIHR/Wellcome Trust Imperial Clinical Research Facility
Country United Kingdom 
Sector Academic/University 
PI Contribution Assisting St Mary hospital and Charing-cross to predict A&E patient demand.
Collaborator Contribution Funding and data assistance (preparation and collection)
Impact None yet
Start Year 2018
 
Description NIH Pakistan 
Organisation National Institute of Health, Pakistan
Country Pakistan 
Sector Public 
PI Contribution Analyse data
Collaborator Contribution Work together on sequencing poliovirus circulating in Pakistan and Afghanistan
Impact manuscript under review
Start Year 2016
 
Description NIRS Queensland 
Organisation QIMR Berghofer Medical Research Institute
Country Australia 
Sector Academic/University 
PI Contribution Providing technical support and specialist knowledge
Collaborator Contribution Data and field expertise
Impact not known
Start Year 2017
 
Description NTD Modelling Consortium 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data.
Impact Scientific publications
Start Year 2015
 
Description NTD Modelling Consortium 
Organisation University of Warwick
Country United Kingdom 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data.
Impact Scientific publications
Start Year 2015
 
Description Naomi model for district-level HIV estimates in sub-Saharan Africa 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution - Developed new model for district-level estimates of HIV prevalence, antiretroviral treatment coverage, and new HIV infections in sub-Saharan Africa. - Developed web-based software interface for district HIV estimates used by national governments in 25 sub-Saharan African countries.
Collaborator Contribution - Provided technical expertise on surveillance data and statistical modelling. - Provided data inputs to modelling. - Supported implementation of software tool with national governments.
Impact - District HIV estimates used for US Government PEPFAR 2020 budget allocations. - Manuscript in preparation. - District level HIV estimates to be publicly released by UNAIDS in June 2020.
Start Year 2019
 
Description Naomi model for district-level HIV estimates in sub-Saharan Africa 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS)
Country Global 
Sector Public 
PI Contribution - Developed new model for district-level estimates of HIV prevalence, antiretroviral treatment coverage, and new HIV infections in sub-Saharan Africa. - Developed web-based software interface for district HIV estimates used by national governments in 25 sub-Saharan African countries.
Collaborator Contribution - Provided technical expertise on surveillance data and statistical modelling. - Provided data inputs to modelling. - Supported implementation of software tool with national governments.
Impact - District HIV estimates used for US Government PEPFAR 2020 budget allocations. - Manuscript in preparation. - District level HIV estimates to be publicly released by UNAIDS in June 2020.
Start Year 2019
 
Description Naomi model for district-level HIV estimates in sub-Saharan Africa 
Organisation United States President's Emergency Plan for AIDS Relief
Country United States 
Sector Public 
PI Contribution - Developed new model for district-level estimates of HIV prevalence, antiretroviral treatment coverage, and new HIV infections in sub-Saharan Africa. - Developed web-based software interface for district HIV estimates used by national governments in 25 sub-Saharan African countries.
Collaborator Contribution - Provided technical expertise on surveillance data and statistical modelling. - Provided data inputs to modelling. - Supported implementation of software tool with national governments.
Impact - District HIV estimates used for US Government PEPFAR 2020 budget allocations. - Manuscript in preparation. - District level HIV estimates to be publicly released by UNAIDS in June 2020.
Start Year 2019
 
Description Naomi model for district-level HIV estimates in sub-Saharan Africa 
Organisation University of Washington
Country United States 
Sector Academic/University 
PI Contribution - Developed new model for district-level estimates of HIV prevalence, antiretroviral treatment coverage, and new HIV infections in sub-Saharan Africa. - Developed web-based software interface for district HIV estimates used by national governments in 25 sub-Saharan African countries.
Collaborator Contribution - Provided technical expertise on surveillance data and statistical modelling. - Provided data inputs to modelling. - Supported implementation of software tool with national governments.
Impact - District HIV estimates used for US Government PEPFAR 2020 budget allocations. - Manuscript in preparation. - District level HIV estimates to be publicly released by UNAIDS in June 2020.
Start Year 2019
 
Description Novel candidate vaccine for Schistoma mansoni 
Organisation Bill and Melinda Gates Foundation
Country United States 
Sector Charity/Non Profit 
PI Contribution Design on end points and potential impact of vaccine in resource poor settings
Collaborator Contribution Implementation of the pilot experiments in animal models and phase I trials in humans
Impact Successful trials in baboons. Imperial team helped analyse trial data
Start Year 2019
 
Description Novel candidate vaccine for Schistoma mansoni 
Organisation National Institutes of Health (NIH)
Country United States 
Sector Public 
PI Contribution Design on end points and potential impact of vaccine in resource poor settings
Collaborator Contribution Implementation of the pilot experiments in animal models and phase I trials in humans
Impact Successful trials in baboons. Imperial team helped analyse trial data
Start Year 2019
 
Description PATH Innovation Collaboration - ANC-based surveillance tool 
Organisation Kenyan Institute for Medical Research (KEMRI)
Department KEMRI/CDC Research and Public Health Collaboration
Country Kenya 
Sector Charity/Non Profit 
PI Contribution I am developing a statistical model using routine testing data from antenatal clinics in Western Kenya to estimate malaria transmission within the general population
Collaborator Contribution In-country collaborators PATH, Kenya Medical Research Institute and the US CDC are responsible for collecting, collating and providing the data, as well as organising dissemination workshops.
Impact A dissemination meeting took place in Kisumu in August 2018.
Start Year 2016
 
Description PATH Innovation Collaboration - ANC-based surveillance tool 
Organisation Program for Appropriate Technology in Health (PATH)
Country United States 
Sector Charity/Non Profit 
PI Contribution I am developing a statistical model using routine testing data from antenatal clinics in Western Kenya to estimate malaria transmission within the general population
Collaborator Contribution In-country collaborators PATH, Kenya Medical Research Institute and the US CDC are responsible for collecting, collating and providing the data, as well as organising dissemination workshops.
Impact A dissemination meeting took place in Kisumu in August 2018.
Start Year 2016
 
Description PATH to pilot novel bednet in pilot intervention trials 
Organisation PATH
Country Global 
Sector Charity/Non Profit 
PI Contribution Provide technical support to help design a programme to monitor the efficacy and effectiveness of the introduction of a new type of bednet in Burkina Faso, Rwanda and Mozambique.
Collaborator Contribution Liaison with National Malaria Control Programmes and local partners to set up data collection and regulatory approval.
Impact Entomological and epidemiological data on the effectiveness of the Interceptor G2 bednet. Data on the ability of near infra-red spectroscopy for monitoring the age of mosquito populations. Update 2020 - Work conducted as part of this project has facilitated funding which will distribute 38 million improved bednets in Africa. Mathematical models predict that this will avert an additional 49.1 million clinical cases of malaria (95% confidence intervals 39.1-55.7 million cases) over the three-year life-expectancy of the net. This will save approximately 73,500 lives during this time.
Start Year 2018
 
Description PB-PG-0317-20039 - Uptake, effectiveness and acceptability of routine screening of pregnant migrants for latent tuberculosis infection in antenatal care: a feasibility study 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Economic analysis
Collaborator Contribution Collecting data
Impact None yet
Start Year 2019
 
Description Policy response to ECHO trial 
Organisation University of California, Berkeley
Country United States 
Sector Academic/University 
PI Contribution Mathematical modelling
Collaborator Contribution Expertise in reproductive health and modelling
Impact Publication in The Lancet
Start Year 2019
 
Description Polio Environmental Surveillance in Dhaka 
Organisation University of Virginia (UVa)
Country United States 
Sector Academic/University 
PI Contribution Statistical and mathematical analysis; genetic sequencing of detected enteroviruses
Collaborator Contribution Collection of demographic data, sewage physicochemical properties and pathogen data from sewage
Impact None yet
Start Year 2018
 
Description Population Dynamics of Human Ascariasis 
Organisation University of Westminster
Country United Kingdom 
Sector Academic/University 
PI Contribution Data analysis, statistical and mathematical modelling through MRc-funded PhD student
Collaborator Contribution Sharing of data on chemo-expulsion studies of Ascaris lumbricoides in Bangladesh for the analysis and modelling of the population dynamics of ascariasis in human populations
Impact Publications, PubMed ID Number: 19208229; 20385140; 20620142
Start Year 2006
 
Description Population genomic statistical methods 
Organisation University of Oslo
Department Department of Oceanography
Country Norway 
Sector Academic/University 
PI Contribution Provided data analysis
Collaborator Contribution They provided software and statistical methods
Impact Software and publications
Start Year 2015
 
Description Predicting the impact of transmission blocking vaccines for malaria 
Organisation National Institutes of Health (NIH)
Country United States 
Sector Public 
PI Contribution Provided expertise in data analysis and mathematical modelling
Collaborator Contribution Provided data from randomised control trial of new vaccine in Burkina Faso
Impact No outputs yet
Start Year 2019
 
Description Preparation of a business case for investment in the development of macrofilaricides for onchocerciasis 
Organisation MM Global Health Consulting
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Modelling the epidemiological impact of hypothetical macrofilaricides in comparison with moxidectin and ivermectin across APOC projects in Africa.
Collaborator Contribution Provision of framework to support business case Regular input Act as liaison with WHO and Bill and Melinda Gates Foundation.
Impact No outputs known yet. Simulations will be linked to economic evaluations at Imperial College London.
Start Year 2019
 
Description Prevention and Restriction on Anti Microbial Resistance AMR) in Pneumococci by Multi Level Modelling 
Organisation The Wellcome Trust Sanger Institute
Department MRC Centre for Genomics and Global Health, WTCHG and WTSI
Country United Kingdom 
Sector Academic/University 
PI Contribution Data analysis and lab work
Collaborator Contribution Data provision
Impact Multiple publications; sequenced data has emerged.Work ongoing on publication.
Start Year 2012
 
Description Priority setting for healthcare services in India 
Organisation Center for Global Development
Country United States 
Sector Charity/Non Profit 
PI Contribution Provision of technical expertise Analysis of data Policy translation (evidence into action)
Collaborator Contribution CHAI - analysis of data NHAI - Policy makers - provision of data and identification of areas of development
Impact No recognised ouputs yet
Start Year 2020
 
Description Priority setting for healthcare services in India 
Organisation Clinton Health Access Initiative
Country United States 
Sector Charity/Non Profit 
PI Contribution Provision of technical expertise Analysis of data Policy translation (evidence into action)
Collaborator Contribution CHAI - analysis of data NHAI - Policy makers - provision of data and identification of areas of development
Impact No recognised ouputs yet
Start Year 2020
 
Description Priority setting for healthcare services in India 
Organisation Government of India
Department National Health Authority, India
Country India 
Sector Public 
PI Contribution Provision of technical expertise Analysis of data Policy translation (evidence into action)
Collaborator Contribution CHAI - analysis of data NHAI - Policy makers - provision of data and identification of areas of development
Impact No recognised ouputs yet
Start Year 2020
 
Description Real time outbreak modelling and analysis 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution Continuous provision on modelling expertise and analysis for ongoing Ebola virus disease outbreak in DRC and current Corona virus outbreak.
Collaborator Contribution Provision of data for analysis and coordination of interactions with additional modelling groups.
Impact 40 reports sent to WHO which have been used to inform situational awareness and fed into policy decisions, particularly estimates of admissibility and future projections of case numbers for Ebola outbreak.
Start Year 2010
 
Description Recent HIV infection surveillance to monitor HIV incidence and evaluate intervention impact 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution - Development of mathematical and statistical models for analysing novel recent HIV infection surveillance data. - Design of evaluation study about impact of secondary schools on HIV risk and pregnancy amongst adolescent girls and young women.
Collaborator Contribution - Collection and interpretation of novel surveillance data.
Impact Not yet recognised
Start Year 2018
 
Description Recent HIV infection surveillance to monitor HIV incidence and evaluate intervention impact 
Organisation Ministry of Health Malawi
Country Malawi 
Sector Public 
PI Contribution - Development of mathematical and statistical models for analysing novel recent HIV infection surveillance data. - Design of evaluation study about impact of secondary schools on HIV risk and pregnancy amongst adolescent girls and young women.
Collaborator Contribution - Collection and interpretation of novel surveillance data.
Impact Not yet recognised
Start Year 2018
 
Description Recent HIV infection surveillance to monitor HIV incidence and evaluate intervention impact 
Organisation University of California, San Francisco
Department School of Medicine (UCSF)
Country United States 
Sector Academic/University 
PI Contribution - Development of mathematical and statistical models for analysing novel recent HIV infection surveillance data. - Design of evaluation study about impact of secondary schools on HIV risk and pregnancy amongst adolescent girls and young women.
Collaborator Contribution - Collection and interpretation of novel surveillance data.
Impact Not yet recognised
Start Year 2018
 
Description Reciprocal capacity building workshop - focus on yellow fever outbreak and response 
Organisation Government of Brazil
Department Ministry of Health Brazil
Country Brazil 
Sector Public 
PI Contribution Provision of expertise in capacity building for modelling and data analytics - particularly for regional partners in LMICs.
Collaborator Contribution MoH - provision of data for analysis Fiocruz - provision of field training for workshop for Imperial staff and coordination of networking
Impact Workshop planned for July 2020.
Start Year 2017
 
Description Reciprocal capacity building workshop - focus on yellow fever outbreak and response 
Organisation Oswaldo Cruz Foundation (Fiocruz)
Country Brazil 
Sector Public 
PI Contribution Provision of expertise in capacity building for modelling and data analytics - particularly for regional partners in LMICs.
Collaborator Contribution MoH - provision of data for analysis Fiocruz - provision of field training for workshop for Imperial staff and coordination of networking
Impact Workshop planned for July 2020.
Start Year 2017
 
Description Reconstructing dengue transmission intensity in Indonesia from multiple dtata sources 
Organisation Sanofi
Country Global 
Sector Private 
PI Contribution Provision of Mathematical modelling expertise
Collaborator Contribution Provision of data Expertise in data interpretation
Impact Publication in PLoS NTDs Poster and talk at ASTMH (American Society of Tropical Medicine and Hygiene)
Start Year 2018
 
Description Reconstructing dengue transmission intensity in Indonesia from multiple dtata sources 
Organisation University of Indonesia
Country Indonesia 
Sector Academic/University 
PI Contribution Provision of Mathematical modelling expertise
Collaborator Contribution Provision of data Expertise in data interpretation
Impact Publication in PLoS NTDs Poster and talk at ASTMH (American Society of Tropical Medicine and Hygiene)
Start Year 2018
 
Description Research to Improve the Detection and Treatment of Latent Tuberculosis Infection (RID-TB) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Economic analysis
Collaborator Contribution Collecting data
Impact None yet
Start Year 2018
 
Description Respiratory infections sample collection 
Organisation Mahidol University
Country Thailand 
Sector Academic/University 
PI Contribution Data analysis
Collaborator Contribution Provide knowledge, data, samples and DNA
Impact Publications; sequenced data
Start Year 2012
 
Description Restriction modification analysis 
Organisation University of Leicester
Department University of Leicester, Proteomics facility
Country United Kingdom 
Sector Academic/University 
PI Contribution Provided strains, DNA and data analysis
Collaborator Contribution Provided techniques and new strains
Impact Publication and sequenced data
Start Year 2015
 
Description START-IPT study collaborator 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution We have produced models of Intermittent Preventive Treatment for malaria in school children, to assist the design of a trial and give an estimate of likely effect.
Collaborator Contribution Design and carrying out a cluster-randomized trial of Intermittent Preventive Treatment for malaria in school children in Uganda.
Impact Informed trial design. The collaboration is multi disciplinary, including mathematical modellers, clinicians, epidemiologists.
Start Year 2014
 
Description Sanofi data collaboration 
Organisation Sanofi
Country Global 
Sector Private 
PI Contribution We have carried out secondary analysis of trial data, to estimate the post-treatment prophylactic effect of artesunate amodiaquine.
Collaborator Contribution They contributed data.
Impact Published in BMC Medicine 2020.
Start Year 2014
 
Description Sarah Cleveland - Glasgow 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Centre Investigator, Christl Donnelly directly involved in the design and analysis of epidemological and ecological data relating to rabies control in Tanzania
Collaborator Contribution Provide data and ecological expertise 
Impact A PhD student, Sarah Hayes -SPH EPSRC scholarship
Start Year 2016
 
Description Sarah Cleveland and Katie Hampson- Glasgow 
Organisation University of Glasgow
Department MRC - University of Glasgow Centre for Virus Research
Country United Kingdom 
Sector Academic/University 
PI Contribution Centre Investigator, Christl Donnelly directly involved in the design and analysis of epidemological and ecological data relating to rabies control in Tanzania
Collaborator Contribution Provide data and ecological expertise 
Impact A PhD student, Sarah Hayes -SPH EPSRC scholarship
Start Year 2016
 
Description Set up of collaborative research partnership 
Organisation Clinton Health Access Initiative
Country United States 
Sector Charity/Non Profit 
PI Contribution Establishment of research collaboration and negotiation of data sharing agreement/materials transfer agreement with collaborators. (Swaziland National Malaria Control Programme).
Collaborator Contribution Agreement to enter into research collaboration and sharing of data for the purpose of this surveillance study. Negotiation of data transfer agreement/materials transfer agreement with collaborators.
Impact None as yet.
Start Year 2017
 
Description Set up of collaborative research partnership 
Organisation Government of Swaziland
Country Swaziland 
Sector Public 
PI Contribution Establishment of research collaboration and negotiation of data sharing agreement/materials transfer agreement with collaborators. (Swaziland National Malaria Control Programme).
Collaborator Contribution Agreement to enter into research collaboration and sharing of data for the purpose of this surveillance study. Negotiation of data transfer agreement/materials transfer agreement with collaborators.
Impact None as yet.
Start Year 2017
 
Description St Georges Hospital 
Organisation St George's University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Research into the genomics of Cryptococcal meningitis. Co-supervision of MRC PhD student
Collaborator Contribution Imperial College: Genomic analysis St Georges Hospital: Clinical trials, phenotypic analyses
Impact See publications list
 
Description Studies on Onchocerciasis-Associated Epilepsy 
Organisation University of Antwerp
Country Belgium 
Sector Academic/University 
PI Contribution Participation in First International Workshop on Onchocerciasis-Associated Epilepsy (OAE), University of Antwerp, October 2017; Chairing Symposium on OAE at the American Society of Tropical Medicine & Hygiene (ASTMH) annual meeting, New Orleans, October 2018; preparation of joint manuscripts Updated February 2020: Preparation and publication of patients in Infectious Diseases of Poverty, PLoS Neglected Tropical Diseases. Mentoring of a PhD student through AIMS Cameroon from transmission dynamics modelling and collaboration on a Wellcome Trust application by the mentored student
Collaborator Contribution Convening and organisation of First International Workshop on Onchocerciasis-Associated Epilepsy (OAE); coordination of the OAE Alliance; organisation of Symposium at ASTMH; drafting of joint manuscripts; submission of Organised Session on Morbidity Management and Disability Prevention for European Congress of Tropical Medicine and International Health (ECTMIH), Liverpool, September 2019 Updated February 2020: Assisting in the implementation of a joint MSc in Epidemiology student to link onchocerciasis transmission models to epilepsy
Impact Published manuscripts (e.g. in Infectious Diseases of Poverty) and manuscripts under review (e.g. in Frontiers in Neurology). Multidisciplinary collaboration: Neurologists; epidemiologists; physicians; social scientists.
Start Year 2017
 
Description Studies on epidemiology, morbidity and control of Loiasis 
Organisation Institute of Development Research (IRD)
Country France 
Sector Academic/University 
PI Contribution Preparation of joint publications published in Trends in Parasitology and Open Forum Infectious Diseases. Supervision of a Foundation Year 2 Postgraduate Medical Training Programme physician Development of mathematical models for Loiasis transmission and control
Collaborator Contribution Preparation of joint publications published in Trends in Parasitology and Open Forum Infectious Diseases. Contribution to data collation and curation
Impact Publication of two papers. Presentations at the Inaugural World NTD day at the London Centre for Neglected Tropical Disease Research.
Start Year 2018
 
Description Testing of Near-Infrared Spectroscopy in Africa - Brian Foy 
Organisation Colorado State University
Country United States 
Sector Academic/University 
PI Contribution There is a clinical trial of a new systemic insecticide ivermectin in Burkina Faso designed to test whether repeated mass drug administrations can suppress the local mosquito population. RIMDAMAL II (https://clinicaltrials.gov/ct2/show/NCT03967054) is a double-blind, cluster randomized trial and we are using Near-Infrared Spectroscopy to determine whether we can detect a difference in the age of the mosquito population in the different arms of the trial.
Collaborator Contribution The work is being lead by Professor Brian Foy of Colorado State University who will provide spectra from mosquitoes from different arms of the randomised control trial. Our estimates of age will be compared to other methods conducted on the same mosquitoes.
Impact The project is highly multidisciplinary including epidemiologists, entomologists, clinicians and computer scientists.
Start Year 2019
 
Description The Broad Institute Genomics Collaboration 
Organisation Broad Institute
Country United States 
Sector Charity/Non Profit 
PI Contribution Whole Genome Sequencing and Analysis
Collaborator Contribution De Novo techniques for whole genome sequencing of Cryptococcus
Impact Manuscripts in preparation Updated 2020: Manuscripts published in mBio and research ongoing
Start Year 2014
 
Description The Global Fund 
Organisation Global Fund to Fight AIDS, Tuberculosis and Malaria
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Modelling of scenarios to support the 2019 Investment Case
Collaborator Contribution Provided scenarios and input data
Impact Global Fund Investment Case: https://www.theglobalfund.org/en/news/2019-02-08-global-partners-commit-to-step-up-the-fight-against-aids-tb-and-malaria/
Start Year 2018
 
Description The farm environment: an overlooked reservoir of Mycobacterium bovis? 
Organisation University of Warwick
Department University of Warwick Research Students Skills Programme
Country United Kingdom 
Sector Academic/University 
PI Contribution Advising on sampling, analysis and interpretation of data, drafting manuscripts and reports
Collaborator Contribution Collecting samples, processing in the laboratory including control samples, drafting manuscripts and reports
Impact Conference presentations
Start Year 2016
 
Description The population dynamics of malaria within the mosquito and how this is influenced by temperature 
Organisation Penn State University
Cou