MRC Centre for Global Infectious Disease Analysis
Lead Research Organisation:
Imperial College London
Department Name: School of Public Health
Abstract
The continuing threat from new infectious diseases has been highlighted in recent years by the emergence of MERS-coronavirus in the Middle East, Ebola in West Africa and Zika in Latin America. Preparing for and responding to such threats is a priority for public health agencies and governments worldwide. Equally importantly, as scientific research delivers new approaches to controlling existing infectious diseases such as malaria, HIV, tuberculosis and polio, there is a need to determine what interventions are likely to work best to limit the disease and illness caused by a specific disease in a particular setting.
In this context, computer modelling of the spread of diseases in populations coupled with scientifically rigorous data analysis have proven themselves as powerful tools for giving insight into how diseases spread and what can be done to limit that control that spread. The Centre for Global Infectious Disease Analysis undertakes research on these scientific methods and applies them to disease threats of concern.
A key feature of the Centre is the close links it has made with with public health agencies - such as the Public Health England, the Centers for Disease Control and Prevention in the US (CDC), and the World Health Organization (WHO) - organisations which have to formulate and implement strategies to control infectious diseases.
Senior scientists in the Centre are world-leaders in infectious disease modelling and analysis. They have broad experience in responding to real epidemics, and undertaking epidemiological research on endemic diseases (such as malaria, HIV, tuberculosis and polio). Their work directly influences disease control policy through the many interactions the Centre has with public health organisations and governments.
Funding provided by MRC and Imperial College has allowed dedicated investment into the development of close collaborative partnerships with PHE, CDC and WHO and governments and research centres in many low and middle income countries (LMICs). We also work closely with other important organisations who work on improving health in LMICs (notably the Bill and Melinda Gates Foundation, The Global Fund and Gavi). With each, our collaborative research has both scientific interest to Centre researchers and contributes to the evidence base for public health decisions. Centre funding supports a core technical capacity available to all projects and pays for dedicated liaison staff who facilitate and enhance our partnerships with major global health organisations and LMICs.
MRC funding has also facilitated a greater focus on collaboration, training and career development within the Centre - training the next generation of quantitative infectious disease epidemiologists. We are also involved in increasing knowledge of advanced modelling methods in public health institutions and the wider infectious disease research community, and so have run a large number of introductory short-courses and workshops (in 13 countries in the last 5 years)
This applied activity depends on more fundamental research undertaken in the Centre on the transmission dynamics of different diseases, how diseases evolve genetically over time, and on analysing new approaches to control or treat diseases. This research is interdisciplinary, with Centre researchers working with leading clinical and experimental scientists around the world.
Continued Centre funding will allow existing partnerships to be sustained and enhanced, and new collaborations with researchers and health agencies in LMICs to be developed. By supporting PhD training and postdoctoral career development, it will also continue to expand the UK skill base in mathematical modelling and advanced analysis applied to health problems. Last, continued MRC support will pump-prime new priority research areas, including work on improving the development of new vaccines and on tackling the global challenge posed by antimicrobial resistance.
In this context, computer modelling of the spread of diseases in populations coupled with scientifically rigorous data analysis have proven themselves as powerful tools for giving insight into how diseases spread and what can be done to limit that control that spread. The Centre for Global Infectious Disease Analysis undertakes research on these scientific methods and applies them to disease threats of concern.
A key feature of the Centre is the close links it has made with with public health agencies - such as the Public Health England, the Centers for Disease Control and Prevention in the US (CDC), and the World Health Organization (WHO) - organisations which have to formulate and implement strategies to control infectious diseases.
Senior scientists in the Centre are world-leaders in infectious disease modelling and analysis. They have broad experience in responding to real epidemics, and undertaking epidemiological research on endemic diseases (such as malaria, HIV, tuberculosis and polio). Their work directly influences disease control policy through the many interactions the Centre has with public health organisations and governments.
Funding provided by MRC and Imperial College has allowed dedicated investment into the development of close collaborative partnerships with PHE, CDC and WHO and governments and research centres in many low and middle income countries (LMICs). We also work closely with other important organisations who work on improving health in LMICs (notably the Bill and Melinda Gates Foundation, The Global Fund and Gavi). With each, our collaborative research has both scientific interest to Centre researchers and contributes to the evidence base for public health decisions. Centre funding supports a core technical capacity available to all projects and pays for dedicated liaison staff who facilitate and enhance our partnerships with major global health organisations and LMICs.
MRC funding has also facilitated a greater focus on collaboration, training and career development within the Centre - training the next generation of quantitative infectious disease epidemiologists. We are also involved in increasing knowledge of advanced modelling methods in public health institutions and the wider infectious disease research community, and so have run a large number of introductory short-courses and workshops (in 13 countries in the last 5 years)
This applied activity depends on more fundamental research undertaken in the Centre on the transmission dynamics of different diseases, how diseases evolve genetically over time, and on analysing new approaches to control or treat diseases. This research is interdisciplinary, with Centre researchers working with leading clinical and experimental scientists around the world.
Continued Centre funding will allow existing partnerships to be sustained and enhanced, and new collaborations with researchers and health agencies in LMICs to be developed. By supporting PhD training and postdoctoral career development, it will also continue to expand the UK skill base in mathematical modelling and advanced analysis applied to health problems. Last, continued MRC support will pump-prime new priority research areas, including work on improving the development of new vaccines and on tackling the global challenge posed by antimicrobial resistance.
Technical Summary
The continued threat posed by emerging infectious diseases has been highlighted in recent years by the emergence of MERS-coronavirus in the Middle East, Ebola in West Africa and Zika in Latin America. Preparedness therefore remains a policy priority for public health agencies and governments worldwide. In addition, as new vaccines, drugs and other interventions are developed for endemic diseases such as malaria, HIV and TB, there is a need to extrapolate from clinical trial results to determine which combination of interventions gives the optimal (or most cost-effective) control strategy for a specific disease in a particular setting.
In this context, modern epidemiological modelling and analysis methods have proven themselves increasingly powerful tools for giving insight into the patterns of emergence of novel outbreaks, the transmission dynamics of endemic diseases and the options available for the control of both. The Centre for Global Infectious Disease Analysis is a world leader in research in this area, and in translating our research into improved public-health decision-making. Since it was founded, MRC funding has supported this translation by facilitating the forging of close partnerships with all major global health organisations (e.g. WHO, PHE, CDC, BMGF, The Global Fund, Gavi) and research centres and public health agencies in many low and middle income countries (LMICs).
Continued funding for the Centre will allow existing partnerships to be sustained and enhanced, and new collaborations with researchers and health agencies in LMICs to be developed. By supporting PhD training and postdoctoral career development, it will also continue to expand the UK skill base in mathematical modelling and advanced analysis applied to health problems. Last, continued MRC support will pump-prime new priority research areas, including work on improving the development of new vaccines and on tackling the global challenge posed by antimicrobial resistance.
In this context, modern epidemiological modelling and analysis methods have proven themselves increasingly powerful tools for giving insight into the patterns of emergence of novel outbreaks, the transmission dynamics of endemic diseases and the options available for the control of both. The Centre for Global Infectious Disease Analysis is a world leader in research in this area, and in translating our research into improved public-health decision-making. Since it was founded, MRC funding has supported this translation by facilitating the forging of close partnerships with all major global health organisations (e.g. WHO, PHE, CDC, BMGF, The Global Fund, Gavi) and research centres and public health agencies in many low and middle income countries (LMICs).
Continued funding for the Centre will allow existing partnerships to be sustained and enhanced, and new collaborations with researchers and health agencies in LMICs to be developed. By supporting PhD training and postdoctoral career development, it will also continue to expand the UK skill base in mathematical modelling and advanced analysis applied to health problems. Last, continued MRC support will pump-prime new priority research areas, including work on improving the development of new vaccines and on tackling the global challenge posed by antimicrobial resistance.
Planned Impact
A primary aim of the MRC Centre for Global Infectious Disease Analysis is to have societal as well as academic impact - both in the UK and across the world. Our goal is to improve public and global health decision making in relation to infectious disease control through the use of advanced statistical and mathematical modelling methods, whether in emergencies like the West African Ebola epidemic in 2014, or in improving control of major infectious disease killers like HIV, malaria and Tuberculosis. We believe the only effective way of delivering on this goal is to form long-term collaborative partnerships with the leading public and global health organisations world-wide, providing analytical support and capacity building for those partners.
Since the Centre was founded in 2008, we have worked on dozens of policy-relevant problems with decision-makers around the world. We provided real-time support to the World Health Organization (WHO), the governments of the UK, and many other international partners during the 2001 H1N1 influenza pandemic, in relation to continued outbreaks of MERS coronavirus in the Middle East, during the 2014-15 West African Ebola epidemic, and, most recently, during the Latin American Zika epidemic. In addition, we have worked closely with WHO and the major international organisations (e.g. The Global Fund, Gavi and the Bill and Melinda Gates Foundation [BMGF]) that fund infectious disease control efforts in low income countries on HIV, malaria, tuberculosis, polio, influenza and a wide range of other diseases. Our relationship with BMGF is of particular strategic importance - it is both the largest funder of Centre research, but more importantly is a key stakeholder in global health decision-making.
These interactions, and our consequent impact on policy, is facilitated by staff dedicated to acting as liaisons between the scientists working in the Centre and the staff of the global and public health agencies we work with. Indeed, in times of crisis, we embed our staff in some of those key organisations. Recently, one of our researchers joined a WHO field mission to the Democratic Republic of Congo to help that country respond to an outbreak of Ebola.
In addition to formal research outputs, often the most important value we give to these organisations is advice provided from a dynamical modelling perspective. This analytical advisory role is multifaceted: from improving situational awareness in crises, advising on likely impact of interventions for endemic diseases, undertaking rapid analyses of priority questions, and advising on improving surveillance and data capture systems.
Capacity building within our partners is another priority, through informal skills transfer and formal training. The former occurs as a natural result of the degree of interaction, and for the latter we run short-courses, both in the Centre and at our partners' sites. Increasingly, we have also been undertaking capacity-building in low and middle income countries [LMIC], either by running disease-specific workshops with local ministries of health, or by training able local scientists. This activity will be further emphasised in the future.
In addition to impact on public health, we have also been increasing our collaborations with the pharmaceutical industry, most notably with vaccine manufacturers. In the last 5 years we have worked closely with GSK and Sanofi Pasteur, helping to characterise the effectiveness of their malaria and dengue vaccines, respectively. Our work involved analysing the data those companies collected on their products during clinical trials and advising them, WHO and regulatory agencies on how their vaccines might best be used. We also work with a wide range of public-private product development partnerships developing new vaccines, drugs and vector control measures.
Attached letters of support from UK DoH, GoS, PHE, US CDC, WHO and BMGF highlight the public health impact of the Centre.
Since the Centre was founded in 2008, we have worked on dozens of policy-relevant problems with decision-makers around the world. We provided real-time support to the World Health Organization (WHO), the governments of the UK, and many other international partners during the 2001 H1N1 influenza pandemic, in relation to continued outbreaks of MERS coronavirus in the Middle East, during the 2014-15 West African Ebola epidemic, and, most recently, during the Latin American Zika epidemic. In addition, we have worked closely with WHO and the major international organisations (e.g. The Global Fund, Gavi and the Bill and Melinda Gates Foundation [BMGF]) that fund infectious disease control efforts in low income countries on HIV, malaria, tuberculosis, polio, influenza and a wide range of other diseases. Our relationship with BMGF is of particular strategic importance - it is both the largest funder of Centre research, but more importantly is a key stakeholder in global health decision-making.
These interactions, and our consequent impact on policy, is facilitated by staff dedicated to acting as liaisons between the scientists working in the Centre and the staff of the global and public health agencies we work with. Indeed, in times of crisis, we embed our staff in some of those key organisations. Recently, one of our researchers joined a WHO field mission to the Democratic Republic of Congo to help that country respond to an outbreak of Ebola.
In addition to formal research outputs, often the most important value we give to these organisations is advice provided from a dynamical modelling perspective. This analytical advisory role is multifaceted: from improving situational awareness in crises, advising on likely impact of interventions for endemic diseases, undertaking rapid analyses of priority questions, and advising on improving surveillance and data capture systems.
Capacity building within our partners is another priority, through informal skills transfer and formal training. The former occurs as a natural result of the degree of interaction, and for the latter we run short-courses, both in the Centre and at our partners' sites. Increasingly, we have also been undertaking capacity-building in low and middle income countries [LMIC], either by running disease-specific workshops with local ministries of health, or by training able local scientists. This activity will be further emphasised in the future.
In addition to impact on public health, we have also been increasing our collaborations with the pharmaceutical industry, most notably with vaccine manufacturers. In the last 5 years we have worked closely with GSK and Sanofi Pasteur, helping to characterise the effectiveness of their malaria and dengue vaccines, respectively. Our work involved analysing the data those companies collected on their products during clinical trials and advising them, WHO and regulatory agencies on how their vaccines might best be used. We also work with a wide range of public-private product development partnerships developing new vaccines, drugs and vector control measures.
Attached letters of support from UK DoH, GoS, PHE, US CDC, WHO and BMGF highlight the public health impact of the Centre.
Organisations
- Imperial College London, United Kingdom (Collaboration, Lead Research Organisation)
- Government of Brazil (Collaboration)
- UNICEF, United States (Collaboration)
- Public Health England, United Kingdom (Collaboration)
- Central University of Venezuela (Collaboration)
- Global Fund to Fight AIDS, Tuberculosis and Malaria (Collaboration)
- University of Yaoundé (Collaboration)
- London School of Economics & Pol Sci, United Kingdom (Collaboration)
- Simprints (Collaboration)
- National Institute of Health, Pakistan (Collaboration)
- Healthsites.io (Collaboration)
- Global Solutions for Infectious Disease (Collaboration)
- University of Pretoria (Collaboration)
- Institute for Health Metrics and Evaluation (IHME) (Collaboration)
- University of Cambridge (Collaboration)
- University of Wisconsin Madison, United States (Collaboration)
- Government of Swaziland (Collaboration)
- Medicines Development for Global Health (Collaboration)
- University of Oxford, United Kingdom (Collaboration)
- Washington University in St. Louis (Collaboration)
- Clinton Health Access Initiative (Collaboration)
- Government of South Africa (Collaboration)
- Human Sciences Research Council (HSRC) (Collaboration)
- Fred Hutchinson Cancer Research Center (FHCRC) (Collaboration)
- World Health Organization (WHO) (Collaboration)
- MRC Dementias Platform UK (Collaboration)
- Colorado State University, United States (Collaboration)
- Antigen Discovery Inc (Collaboration)
- Jinan University (Collaboration)
- Ministry of Health, Ethiopia (Collaboration)
- World Vision Ethiopia (Collaboration)
- Mahidol University (Collaboration)
- National Institutes of Health, United States (Collaboration)
- Ministry of Health and Child Welfare of the Republic of Zimbabwe (Collaboration)
- Program for Appropriate Technology in Health (PATH) (Collaboration)
- King's College London, United Kingdom (Collaboration)
- University of Leicester, United Kingdom (Collaboration)
- University College London, United Kingdom (Collaboration)
- National Institute for Biological Standards and Control (NIBSC) (Collaboration)
- Institute of Tropical Medicine (Collaboration)
- Christian Medical College Vellore (Collaboration)
- Ethiopian Public Health Institute (Collaboration)
- Simon Fraser University, Canada (Collaboration)
- Johnson & Johnson Ltd, United Kingdom (Collaboration)
- Medicines for Malaria Venture (MMV) (Collaboration)
- University of Queensland, Australia (Collaboration)
- Foundation for Innovative New Diagnostics (FIND) (Collaboration)
- University of Ghent, Belgium (Collaboration)
- Sanofi (Collaboration)
- Edmund Mach Foundation (Collaboration)
- MM Global Health Consulting (Collaboration)
- University of Hong Kong, Hong Kong (Collaboration)
- Pennsylvania State University, United States (Collaboration)
- University Hospital of Laval University (Collaboration)
- Government of the UK (Collaboration)
- University of California, San Francisco, United States (Collaboration)
- Drugs for Neglected Diseases initiative (DNDi) (Collaboration)
- Sixth Framework Programme (FP6) (Collaboration)
- The Wellcome Trust Sanger Institute (Collaboration)
- Erasmus University Rotterdam (EUR) (Collaboration)
- Sorbonne University (Collaboration)
- McGill University, Canada (Collaboration)
- University of Bamako (Collaboration)
- University of Surrey, United Kingdom (Collaboration)
- Government of Colombia (Collaboration)
- Worldwide Antimalarial Resistance Network (Collaboration)
- PATH (Collaboration)
- Institute of Development Research (IRD) (Collaboration)
- U.S. Department of Agriculture USDA (Collaboration)
- Experimental Zooprophylactic Institute of the Venezie (Collaboration)
- Centre for Infectious Disease Research in Zambia (Collaboration)
- Royal Veterinary College, United Kingdom (Collaboration)
- University of the Witwatersrand, South Africa (Collaboration)
- The African Institute of Biomedical Science and Technology (Collaboration)
- National University of Río Negro (Collaboration)
- Johns Hopkins University, United States (Collaboration)
- Universite Montpellier (Collaboration)
- Takeda Pharmaceutical Company (Collaboration)
- University of Gothenburg, Sweden (Collaboration)
- University of California, Berkeley (Collaboration)
- International Society for Infectious Diseases (ISID) (Collaboration)
- University of Cape Town (Collaboration)
- Population Services International (Collaboration)
- Government of Madagascar (Collaboration)
- Diocese of Mutare Community Care Programme (Collaboration)
- Harvard University (Collaboration)
- University of Liverpool, United Kingdom (Collaboration)
- Research Institute for Health Sciences (IRSS) (Collaboration)
- Medical Research Council of South Africa (MRC) (Collaboration)
- University of Virginia, United States (Collaboration)
- Indian Ministry of Health (Collaboration)
- Africa Health Research Institute (Collaboration)
- International Epidemiologic Databases to Evaluate AIDS (IeDEA) (Collaboration)
- University of Indonesia, Indonesia (Collaboration)
- University of Grenoble (Collaboration)
- Centers for Disease Control and Prevention (CDC) (Collaboration)
- University of Antwerp, Belgium (Collaboration)
- United States President's Emergency Plan for AIDS Relief (Collaboration)
- University of Bristol, United Kingdom (Collaboration)
- Janssen Pharmaceutica NV (Collaboration)
- London Sch of Hygiene and Trop Medicine, United Kingdom (Collaboration)
- University of Glasgow, United Kingdom (Collaboration)
- Centre for Global Development (Collaboration)
- Technical University of Munich (Collaboration)
- Baylor School (Collaboration)
- Ministry of Health, Kenya (Collaboration)
- University of Copenhagen, Denmark (Collaboration)
- University of Sussex, United Kingdom (Collaboration)
- Wellcome Trust, LONDON (Collaboration)
- Wits Health Consortium (Collaboration)
- International Agency for Research on Cancer (IARC) (Collaboration)
- Global Health Asia Institute (Collaboration)
- MURAZ Center (Collaboration)
- Aurum Institute (Collaboration)
- Government of India (Collaboration)
- QIMR Berghofer Medical Res Institute (Collaboration)
- Pan American Health Organization (Collaboration)
- Avenir Health (Collaboration)
- The Statens Serum Institute (SSI) (Collaboration)
- University of Trento, Italy (Collaboration)
- University of Westminster, United Kingdom (Collaboration)
- United Nations (UN) (Collaboration)
- Ministry of Health Malawi (Collaboration)
- Government of The Gambia (Collaboration)
- Government of the United States of America (Collaboration)
- Oswaldo Cruz Foundation (Fiocruz) (Collaboration)
- Princeton University, United States (Collaboration)
- Cardiff University, United Kingdom (Collaboration)
- HealthMap (Collaboration)
- Roehampton University, United Kingdom (Collaboration)
- Natural History Museum (Collaboration)
- Rakai Health Sciences Program (Collaboration)
- Pasteur Institute, Paris (Collaboration)
- MRC/UVRI Uganda Research Unit on AIDS, Uganda (Collaboration)
- Joint United Nations Programme on HIV/AIDS (UNAIDS) (Collaboration)
- University of Warwick, United Kingdom (Collaboration)
- Zoological Soc London Inst of Zoology, United Kingdom (Collaboration)
- University of Oslo, Norway (Collaboration)
- Public Health Institute of Malawi (Collaboration)
- St George's University of London, United Kingdom (Collaboration)
- Bill and Melinda Gates Foundation (Collaboration)
- Stellenbosch University, South Africa (Collaboration)
- Medical Research Council (Collaboration)
- Broad Institute (Collaboration)
- Major National University of San Marcos (Collaboration)
- European Centre for Disease Prevention and Control (ECDC) (Collaboration)
- United States Department of State (Collaboration)
- Kenya National Malaria Control Programme (Collaboration)
- Biomedical Research and Training Inst, Zimbabwe (Collaboration)
- Kenyan Institute for Medical Research (KEMRI) (Collaboration)
- Phramongkutklao College of Medicine (Collaboration)
- Liverpool School of Tropical Medicine (Collaboration)
People |
ORCID iD |
| Neil Ferguson (Principal Investigator) |
Publications
Gaythorpe KAM
(2019)
Quantifying model evidence for yellow fever transmission routes in Africa.
in PLoS computational biology
Gaythorpe KA
(2020)
The effect of climate change on yellow fever disease burden in Africa.
in eLife
Furi L
(2019)
Methylation Warfare: Interaction of Pneumococcal Bacteriophages with Their Host.
in Journal of bacteriology
Fu H
(2020)
Explaining age disparities in tuberculosis burden in Taiwan: a modelling study.
in BMC infectious diseases
Fu H
(2021)
Modelling the global burden of drug-resistant tuberculosis avertable by a post-exposure vaccine
in Nature Communications
Fu H
(2021)
Database of epidemic trends and control measures during the first wave of COVID-19 in mainland China.
in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Friebel R
(2019)
On results reporting and evidentiary standards: spotlight on the Global Fund.
in Lancet (London, England)
Friebel R
(2019)
The Global Fund impact - Authors' reply
in The Lancet
Friebel R
(2018)
Centralisation of acute stroke services in London: Impact evaluation using two treatment groups.
in Health economics
| Description | Active case finding in South India |
| Geographic Reach | Asia |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Impact | Modelling analysis helped local authorities in their decision making for how to implement a highly resource intensive activity (active case finding) in a more efficient way. Guidance allowed a 20% increase in numbers of x-rays being diagnosed for TB. Awaiting further data to assess further impact on patient outcomes. |
| Description | Advise to Chinese government to set up national procurement |
| Geographic Reach | Asia |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Centralized national procurement process for pharmaceuticals was established in China based on this advise, launched in 2018. |
| Description | Advising on global polio policy to the Global Polio Eradication Initiative |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Guidance on vaccine choice during polio eradication endgame, release of global stockpile, development of a new oral poliovirus vaccine |
| Description | Advisory Board of Parasites & Vectors |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Shaping up the scope of the journal; engagement with contributors; advising the Editor-in-Chief |
| Guideline Title | 2018 BASHH UK national guideline for the management of infection with Mycoplasma genitalium |
| Description | British Association for Sexual Health and HIV guidelines on public health management of Mycoplasma genitalium and antimicrobial resistance |
| Geographic Reach | National |
| Policy Influence Type | Citation in clinical guidelines |
| URL | https://www.bashh.org/news/news/bashh-launches-new-nice-accredited-guidelines-to-help-prevent-mycopl... |
| Description | Chair of Oriole Global Health Limited |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Chair of OGH Limited which is helping UK Aid and DFID deliver the ASCEND project for the control of NTDs in resource poor settings. |
| URL | https://orioleglobalhealth.com |
| Description | Citation in Blackett review |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| URL | https://www.gov.uk/government/publications/computational-modelling-blackett-review |
| Description | Citation in GAVI decision to support HBV birth dose |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| URL | https://www.gavi.org/our-alliance/strategy/vaccine-investment-strategy |
| Description | Co-wrote a WHO protocol for assessing non-inferiority of bednets and indoor residual sprays |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | We have devised a protocol to enable novel vector control products that are part of an existing intervention class to be recommended by the WHO (and therefore purchased by the Global Fund) without the need to go through expensive randomised control trials. Update 2020 - The policy was refined and accepted by the Malaria Programme Advisory Comittee at the WHO. New bednets are currently being distributed across Africa which are predicted to have a significant public health benefit to the people using them. |
| Description | Collaboration with WHO Global Malaria Programme |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| Impact | This publication was cited in new policy guidance for the use of current rapid diagnostic tests for malaria, including guidance on when to switch test type if resistance mutations are present. |
| URL | https://www.who.int/malaria/mpac/en/ |
| Description | Commonwealth Heads of Government Malaria Committment |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| URL | https://www.malariasummit.com/ |
| Description | Comparison of different brands of bed nets |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Determine methods to ensure that bed nets procured by governments and charitable organisations are of an efficient standard |
| Description | Contribution to Kenya's National Strategic Plan for TB control |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| Guideline Title | HBV prevention of mother-child transmission |
| Description | Contribution to and citation in WHO guideline for HBV prevention of mother-child transmission |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in clinical guidelines |
| Description | Directing London Centre for NTD research - Helping deliver impact in the control of infectious diseases in resource poor settings |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Gave evidence to a government review |
| Impact | Creation of an evidence base of how best to control NTDs. Influence on WHO guidelines for disease control and funding by philanthropic organisations, (GATES and CIFF). Guidelines hope to improve health in resource poor settings. |
| URL | https://www.lshtm.ac.uk/newsevents/news/2013/ntd_research_launch.html |
| Description | EU policy on banning trade in vector species infected with Batrachochytrium salamandrivorans fungus |
| Geographic Reach | Europe |
| Policy Influence Type | Citation in other policy documents |
| Impact | Biosecurity-relevant policy on banning the import of vector species with a view to stopping the introduction of Batrachochytrium salamandrivorans into the EU |
| URL | https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32018D0320&from=EN |
| Description | Elimination Scenario Planning Exercise with Senegal & The Gambia |
| Geographic Reach | Africa |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Impact | Supported by The Global Fund, in 2016-2017 we undertook three workshops to support malaria country programme planning with The Gambia and Senegal. The last of these, in March 2017, was a joint workshop between the two programmes in which we coordinated discussions surrounding cross-border collaboration between the two countries. Our role in supporting the establishment of this new collaboration was acknowledged at the Malaria Summit held ahead of the Commonwealth Heads of Government meeting by the President of The Gambia (see URL below - we are mentioned in the film). A formal collaboration between the two countries was signed in January 2019. |
| URL | https://www.malariasummit.com/ |
| Description | GAVI Vaccine Investment Strategy |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Membership of the GAVI Vaccine Investment Strategy Committee which provided the scientific input for the recommendation of new vaccines to be supported by GAVI in the upcoming replenishment. This has a direct impact on worldwide childhood vaccination strategies. |
| URL | https://www.gavi.org/about/strategy/vaccine-investment-strategy/ |
| Description | HPCs-UNAIDS |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a national consultation |
| Description | HPCs-Zimbabwe |
| Geographic Reach | National |
| Policy Influence Type | Participation in a national consultation |
| Description | Informing strategic priorities for TB elimination in Mumbai, India |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Citation in other policy documents |
| Description | Malaria Policy Advisory Committee |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Impact | This committee provides advice directly to the WHO Global Malaria Programme on all topics relevant to malaria control and elimination. WHO guidance has direct impact on the policies adopted by national government, which over the past year has included amendment of treatment protocols, advice on current and new prevention interventions, allocation of global donor funding and certification of malaria elimination. |
| URL | https://www.who.int/malaria/mpac/en/ |
| Description | Member of Executive Management of Neglected Tropical Disease Modelling Consortium |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | Member of Influenza Incidence Analytics Group |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Member of expert group for MoD (Confidential) |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Membership of WHO Technical Advisory Group on Health benefit packages |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Issue WHO guidance on how to design healthcare packages eg Universal Healthcare Coverage |
| Description | Membership of regional WHO advisory committee on multi-drug-resistant TB in South East Asian Region |
| Geographic Reach | Asia |
| Policy Influence Type | Participation in a advisory committee |
| Description | Methods development for global HIV estimates and projections |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | We developed new mathematical models used to estimate and project trends in the global HIV epidemic. These models are used by all countries in sub-Saharan Africa and over 150 countries globally to develop official national estimates of their HIV epidemic and plan, budget, and allocate resources to the HIV response. Estimates are reported by UNAIDS as official global HIV estimates and projection, and they form consensus estimates underpinning resource allocation by the US President's Emergency Plan for AIDS Relief (PEPFAR) and the Global Fund to fight HIV, TB, and Malaria. |
| URL | http://aidsinfo.unaids.org |
| Description | NERVTAG (New and Emerging Respiratory Virus Threats Advisory Group) - Since 2015 |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| URL | https://www.gov.uk/government/groups/new-and-emerging-respiratory-virus-threats-advisory-group |
| Description | Pandemic influenza preparedness - advice to government |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Effective preparedness and response to pandemics, which are the highest category of risk identified on the National Risk Register of Civil Emergencies. This is an ongoing activity, supported by multiple relevant grants spanning different time-periods. Updated 2020: Involvement in coronavirus real time analysis and advice |
| Description | Participation in WHO consultation process for setting the 2030 Roadmap on Neglected Tropical Diseases |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Report of the consultation meeting by the WHO - Neglected Tropical Disease Modelling Consortium Report Open Letter for Gates Open Research on Onchocerciasis, Chagas Disease and Taeniasis/Cysticercosis - contribution by ICL by highlighting insights from mathematical modelling in these 3 disciplines for the achievement of the 2030 NTD goals. Will result in increases in survival. improved quality of life for patients, decrease in disease burden and infection. This modelling can be used with economic modelling to assess the cost effectiveness of the interventions modelled. |
| URL | https://www.who.int/neglected_diseases/news/WHO-launches-global-consultations-for-new-NTD-Roadmap/en... |
| Description | Presentation and participation in WHO Technical Consultation in Research priorities for the use of more highly sensitive diagnostics during pregnancy |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| URL | https://www.who.int/malaria/mpac/mpac-april2018-hi-sensitive-tests-session5.pdf?ua=1 |
| Description | Publication of work about Evidence Synthesis for Policy |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| URL | https://royalsociety.org/topics-policy/projects/evidence-synthesis/ |
| Description | Published estimates of Impact of President's Malaria Initiative used in 12th annual report to congress |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| Impact | Our estimates, published in PLoS Medicine, of the impact of the PMI since it's conception were used by PMI in it's report to congress. This report is used to advocate for resources for malaria prevention across 19 focus countries, amid a time when the US' contribution to foreign aid was being questioned. |
| URL | https://www.pmi.gov/docs/default-source/default-document-library/pmi-reports/2018-pmi-twelfth-annual... |
| Description | RDTs-WHO |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a national consultation |
| Impact | Evidence generated on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment contributed to a decision in Zimbabwe (and possibly elsewhere) to adopt a World Health Organisation recommendation to implement repeat HIV testing prior to initiating people onto antiretroviral treatment. This change in policy will reduce the numbers of HIV-negative people put on potentially life-long treatment, will reduce the occurrence of unnecessary side effects, and will reduce unnecessary expenditure. |
| Description | Scientific Advisory Group for Emergencies (SAGE) - Covid-19 |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Scientific Pandemic Influenza Group on Modelling (SPI-M-O) (since 2009) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| URL | https://www.gov.uk/government/publications/spi-m-publish-updated-modelling-summary |
| Description | Scientific committee for Pandemic Influenza - Modelling (SPI-M) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Evidence given to SPI_M committee directly influenced early messaging about the severity of COVID-19. |
| URL | https://www.gov.uk/government/groups/scientific-pandemic-influenza-subgroup-on-modelling |
| Description | Strategic Technical Advisory Group for Infectious Hazards at WHO |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Influence on continued operational response for Ebola outbreak in DRC - has led to increased situational awareness of epidemiological trends. HAs led to improved service provision from international organisations. |
| URL | https://www.who.int/emergencies/diseases/strategic-and-technical-advisory-group-for-infectious-hazar... |
| Description | Support MSF surveillance of malaria policy |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Provided evidence to allow MSF to monitor malaria severity using antinatal clinic data |
| URL | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114784 |
| Description | Support the development of guidelines for malaria surveillance in near-elimination settings. We have outlined a set of questions that should be asked to estimate whether an identified case of malaria was acquired locally or imported from abroad. These include statements on the time and location of travel, duration of stay and date of arrival of symptoms. Questions trailed in regions of South Africa. |
| Geographic Reach | Africa |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | TB control priorities in India |
| Geographic Reach | Asia |
| Policy Influence Type | Gave evidence to a government review |
| Description | Talk given to All Party PArliamentary Group on Biosecurity re COVID-19 |
| Geographic Reach | National |
| Policy Influence Type | Gave evidence to a government review |
| URL | https://www.parliament.uk/mps-lords-and-offices/offices/bicameral/post/post-events/future-biosecurit... |
| Description | Typhoid environmental surveillance advisory group for the Gates Foundation |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | UNAIDS reference group |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Impact | From 2015 to 2018, I co-chaired the UNAIDS Reference Group on Estimates, Modelling and Projections. This group advises UNAIDS and WHO on the methods used to generate international estimates of HIV infection and it's demographic impact. During this period, significant progress was made in improving these estimates - for example, for children infected with HIV, by incorporating age-structure into the models, and in producing local estimates of levels of HIV infection - that can be used to strengthen national HIV control programmes and, thereby, to further reduce levels of new infections and mortality. |
| URL | http://www.epidem.org/ |
| Guideline Title | WHO Dengue Vaccination recommendation |
| Description | WHO Dengue Vaccination recommendation |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in clinical guidelines |
| Impact | Recommendations on optimal vaccine use has led to changes in the delivery of vaccines in relevant populations |
| URL | https://www.who.int/wer/2016/wer9130.pdf?ua=1 |
| Description | WHO Flu Burden |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | WHO policy of recommending the use of second-in-class bednets against malaria |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Impacts not yet recognised |
| Description | WHO spread of pyrethroid resistant mosquitoes across Africa. |
| Geographic Reach | Africa |
| Policy Influence Type | Participation in a advisory committee |
| Impact | Collaboration with the World Health Organisation (WHO) Global Malaria Programme to understand the spread of pyrethroid resistant mosquitoes across Africa and how this influences the effectiveness of insecticide treated bednets used to control malaria. Though this has not led to any specific policy recommendations the work was presented in a WHO document (World Malaria Report 2019, Global report on insecticide resistance in malaria vectors: 2010-2016, accessed https://www.who.int/malaria/publications/atoz/9789241514057/en/ ) and on a live WHO webinar (https://apps.who.int/iris/bitstream/handle/10665/274556/WHO-CDS-GMP-2018.17-eng.pdf?ua=1). This work has supported the development of online threat maps for insecticide resistance status (https://www.who.int/malaria/maps/threats-about/en/). |
| URL | https://www.who.int/malaria/publications/atoz/9789241514057/en/ |
| Description | WHO world malaria report |
| Geographic Reach | Africa |
| Policy Influence Type | Citation in other policy documents |
| Impact | Tracking of ITN numbers and use |
| Description | World Malaria Report 2019 |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| Impact | Published estimates of exposure and burden of malaria during pregnancy and associated Low birthweight were incorporated into official WHO estimates underpinning the World Malaria Report estimates of malaria burden and progress. |
| URL | https://www.who.int/publications-detail/world-malaria-report-2019 |
| Description | Zimbabwe national AIDs council - workshop on HIV prevention cascade |
| Geographic Reach | Africa |
| Policy Influence Type | Participation in a national consultation |
| Description | A genealogical approach to tracking bacterial transmission (Xavier Didelot) |
| Amount | £403,170 (GBP) |
| Funding ID | MR/N010760/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 05/2019 |
| Description | A search-engine inspired platform enabling open sharing and access of both data and results from all genomic studies |
| Amount | £38,832 (GBP) |
| Funding ID | 219699/Z/19/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 01/2021 |
| Description | ALPHA network: HIV incidence trends and risk factors to describe patterns and risks for HIV incidence in selected communities in Southern and Eastern Africa |
| Amount | £170,846 (GBP) |
| Funding ID | EPPHZM5513/Imperial |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 10/2018 |
| End | 09/2020 |
| Description | APW WHO Global Malaria Programme |
| Amount | £17,932 (GBP) |
| Funding ID | 202011200 |
| Organisation | World Health Organization (WHO) |
| Sector | Public |
| Country | Global |
| Start | 06/2018 |
| End | 03/2019 |
| Description | Alessandra Lochen - PhD project support June2017 - Dec2020 |
| Amount | £119,955 (GBP) |
| Funding ID | PO 480075829 |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 07/2019 |
| End | 12/2023 |
| Description | Analysis of ALPHA Network |
| Amount | £37,490 (GBP) |
| Funding ID | PR2017/724002 EPPHZL91/IMPERIAL |
| Organisation | Joint United Nations Programme on HIV/AIDS (UNAIDS) |
| Sector | Public |
| Country | Global |
| Start | 12/2017 |
| End | 11/2018 |
| Description | Analytic and sequencing tools for poliovirus environmental surveillance |
| Amount | £876,522 (GBP) |
| Funding ID | OPP1171890 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 05/2017 |
| End | 11/2020 |
| Description | Antibiotic Resistance: Mathematical modelling simulating the evolutionary response of genococcus within human populations to gepotidacin use |
| Amount | £151,716 (GBP) |
| Funding ID | 3000862100 |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 06/2017 |
| End | 06/2019 |
| Description | Assessing the impact of waning vaccine efficacy on malarial elimination using a population transmission model |
| Amount | £61,597 (GBP) |
| Funding ID | GAT.0888-30-01320457-COL |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 10/2016 |
| End | 11/2018 |
| Description | Assessing the risk that chytridiomycosis poses to the megadiverse amphibian community of Madagascar |
| Amount | £119,900 (GBP) |
| Funding ID | D16ZO-022 |
| Organisation | Morris Animal Foundation |
| Sector | Private |
| Country | United States |
| Start | 09/2016 |
| End | 04/2020 |
| Description | BMGF Project Grant: Vaccine Modelling Initiative (VMI) 2 |
| Amount | £970,053 (GBP) |
| Funding ID | OPP1092240 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 06/2013 |
| End | 06/2020 |
| Description | Beyond 90-90-90: Phylodynamic analysis to guide HIV surveillance, control & elimination |
| Amount | £293,580 (GBP) |
| Organisation | Imperial College London |
| Department | School of Public Health |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 11/2021 |
| Description | Building International Collaborations on the Mathematical Modelling of Emerging Infectious Disease Threats (Neil Ferguson) |
| Amount | £49,657 (GBP) |
| Funding ID | P11329/DF118 |
| Organisation | Imperial College London |
| Department | Imperial College Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2008 |
| End | 12/2020 |
| Description | Building TRUST |
| Amount | £112,438 (GBP) |
| Funding ID | Sub Award No. 1800014 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 07/2015 |
| End | 06/2019 |
| Description | Control of TB in India: developing analytical tools |
| Amount | £385,936 (GBP) |
| Funding ID | OPP1095710 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2013 |
| End | 03/2020 |
| Description | Defining disease importation and target interventions from routine surveillance data |
| Amount | $100,000 (USD) |
| Funding ID | OPP1161898 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2016 |
| End | 04/2018 |
| Description | Develop a novel, cost-effective, surveillance approach for malaria elimination through existing antenatal care platform |
| Amount | £56,255 (GBP) |
| Organisation | PATH |
| Sector | Charity/Non Profit |
| Country | Global |
| Start | 02/2018 |
| End | 08/2018 |
| Description | Developing modelling approaches for influenza control in the USA |
| Amount | £210,020 (GBP) |
| Funding ID | BAA 75D301-19-R-67835 |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Sector | Public |
| Country | United States |
| Start | 08/2019 |
| End | 08/2020 |
| Description | Development and pilot implementation of rapid poliovirus detection and sequencing from stool samples using nanopore technology |
| Amount | £197,654 (GBP) |
| Funding ID | OPP1207299 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2018 |
| End | 03/2020 |
| Description | Development of Methods to Measure and Interpret HIV Prevention Cascades in Population-Based Surveys |
| Amount | £766,317 (GBP) |
| Funding ID | OPP1161471 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2016 |
| End | 07/2020 |
| Description | Deworm3 unit for transmission dynamics, trial simulation and data analysis |
| Amount | £1,163,766 (GBP) |
| Funding ID | SON15004 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 04/2016 |
| End | 09/2020 |
| Description | Dynamic Modelling of HSV-2 and HIV Infections to Estimate the Burden of HSV-associated HIV Infections and the Predicted Impact of HSV Vaccines |
| Amount | £111,917 (GBP) |
| Funding ID | 202002015 |
| Organisation | World Health Organization (WHO) |
| Sector | Public |
| Country | Global |
| Start | 05/2018 |
| End | 12/2019 |
| Description | Early antiretroviral therapy and pre-exposure prophylaxis for HIV prevention among emale sex workers in Benin, West Africa |
| Amount | £121,857 (GBP) |
| Funding ID | OPP1098973 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 08/2014 |
| End | 12/2018 |
| Description | Ed Parker: The effect of maternal and neonatal viral exposure on innate and adaptive immune function |
| Amount | £34,726 (GBP) |
| Funding ID | 204834/Z/16/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2018 |
| End | 08/2019 |
| Description | Epidemiological analysis and mathematical modelling of poliovirus elimination and endgame vaccination strategies |
| Amount | £236,130 (GBP) |
| Funding ID | 2017/769688-0 |
| Organisation | World Health Organization (WHO) |
| Sector | Public |
| Country | Global |
| Start | 11/2017 |
| End | 08/2019 |
| Description | Evaluation work by LCNTDR for the Geshiaro project in support of EPHI |
| Amount | £383,276 (GBP) |
| Funding ID | R-1701-01771 |
| Organisation | Children's Investment Fund Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2018 |
| End | 06/2023 |
| Description | Evolutionary dynamics underlying pneumococcal genomic diversity |
| Amount | £640,778 (GBP) |
| Funding ID | 104169/Z/14/A |
| Organisation | Sir Henry Dale Fellowships |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 09/2022 |
| Description | Evolutionary dynamics underlying pneumococcal genomic diversity. |
| Amount | £708,513 (GBP) |
| Funding ID | 104169/Z/14/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 09/2019 |
| Description | Explore the Pathway of China NICE-like Mechanism by Piloting Three Suggested Projects |
| Amount | £172,623 (GBP) |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 12/2017 |
| End | 05/2019 |
| Description | Fellow Marga Pons Salort (Emergence and global epidemiology of non-polio enteroviruses) |
| Amount | £909,233 (GBP) |
| Funding ID | 216427/Z/19/Z |
| Organisation | Sir Henry Dale Fellowships |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 12/2024 |
| Description | Geospatial modelling for malaria risk stratification and intervention targeting |
| Amount | £219,507 (GBP) |
| Funding ID | 1606H5002/JH6 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 09/2016 |
| End | 08/2020 |
| Description | HC-HIV modeling activity |
| Amount | £156,940 (GBP) |
| Funding ID | 48345 |
| Organisation | United States Agency for International Development |
| Sector | Public |
| Country | United States |
| Start | 06/2017 |
| End | 08/2018 |
| Description | HIV Modelling Consortium Renewal |
| Amount | £3,527,347 (GBP) |
| Funding ID | OPP1084364 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 06/2013 |
| End | 01/2019 |
| Description | Human Infectious Challenge Vaccine (HIC vac) network |
| Amount | £2,041,189 (GBP) |
| Funding ID | MR/R005982/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2018 |
| End | 02/2020 |
| Description | IDC Genomics Lab refurb |
| Amount | £125,000 (GBP) |
| Organisation | St. Mary's Development Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2018 |
| End | 06/2020 |
| Description | ISID/ESCMID Fellowship - Using seroprevalence age profiles to identify changes in incidence and interruption of transmission of filarial infections in Mali |
| Amount | £6,125 (GBP) |
| Organisation | International Society for Infectious Diseases (ISID) |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 04/2019 |
| End | 06/2020 |
| Description | Immunological investigation for the implenatation of Live Attenuated Influenza Vaccination |
| Amount | £811,303 (GBP) |
| Funding ID | MR/R021643/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2018 |
| End | 12/2021 |
| Description | Impact of maternally derived antibodies and microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants |
| Amount | £255,266 (GBP) |
| Funding ID | JXR11990 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 12/2018 |
| Description | Improving HIV phylodynamic research capacity in Botswana |
| Amount | £13,580 (GBP) |
| Organisation | United Kingdom Research and Innovation |
| Department | Global Challenges Research Fund |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 07/2020 |
| Description | Improving the efficacy of malaria prevention in an insecticide resistant Africa |
| Amount | £162,798 (GBP) |
| Funding ID | 200222/B/15/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 10/2019 |
| Description | Integrating Ethics and Equity into Priority Setting for Universal Health Coverage: A Proof-of-Concept Study in South Africa |
| Amount | £128,944 (GBP) |
| Funding ID | 208045/Z/17/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 01/2020 |
| Description | Joint estimation of HIV and adult mortality trends in sub-Saharan Africa |
| Amount | £67,680 (GBP) |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 08/2018 |
| End | 12/2019 |
| Description | Key populations and HIV epidemics in Sub-Saharan Africa: Developing better epidemiologic tools to inform priorities and programs |
| Amount | £179,258 (GBP) |
| Funding ID | PO: 2003388501 |
| Organisation | Family Health International |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 06/2016 |
| End | 03/2019 |
| Description | Kris Parag: Minimum Models for Optimal Epidemic Monitoring and Control |
| Amount | £288,432 (GBP) |
| Funding ID | MR/S019693/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2018 |
| End | 10/2021 |
| Description | London Centre for NTD Research |
| Amount | £555,000 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 06/2015 |
| End | 05/2019 |
| Description | London Centre for NTD Research (renewal 3) |
| Amount | £785,649 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 06/2018 |
| End | 05/2021 |
| Description | MIDAS 2: Models for synthesising molecular, clinical and epidemiological data, and translation to public health response (NIH) |
| Amount | £1,246,328 (GBP) |
| Funding ID | 1U01GM110721-01 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 09/2014 |
| End | 05/2019 |
| Description | MIDAS: Modeling Epidemic Infectious Diseases Using Sequence Analysis |
| Amount | £300,028 (GBP) |
| Funding ID | 258162IMP |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 01/2016 |
| End | 05/2020 |
| Description | Malaria Eradication Metrics |
| Amount | £222,688 (GBP) |
| Funding ID | CRR00280 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 03/2019 |
| End | 09/2021 |
| Description | Mapping the risk of international infectious disease spread |
| Amount | £120,202 (GBP) |
| Funding ID | AID-OAA-F-16-00115 |
| Organisation | United States Agency for International Development |
| Sector | Public |
| Country | United States |
| Start | 10/2016 |
| End | 12/2018 |
| Description | Mathematical Modelling of Microfilaricidal Drugs for River Blindness: from Patients to Populations |
| Amount | £50,870 (GBP) |
| Organisation | Drugs for Neglected Diseases initiative (DNDi) |
| Sector | Charity/Non Profit |
| Country | Switzerland |
| Start | 06/2016 |
| End | 05/2019 |
| Description | Mathematical modeling in the HPTN Renewal |
| Amount | £724,350 (GBP) |
| Funding ID | 2UMIAI068617 Sub#0000800798 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 01/2014 |
| End | 11/2020 |
| Description | Mathematical modelling of poliovirus transmission to support the endgame |
| Amount | £487,817 (GBP) |
| Funding ID | OPP1099374 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2013 |
| End | 07/2018 |
| Description | Maximising the public health impact of new approaches to control malaria in pregnancy through the translation of evidence-based global policies to country level policies and plans. |
| Amount | £42,075 (GBP) |
| Funding ID | CSA-2014-276 |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 01/2016 |
| End | 12/2018 |
| Description | Model development for the draft WHO global report on insecticide resistance in malaria vectors |
| Amount | £13,901 (GBP) |
| Funding ID | 2018/797131-0 |
| Organisation | World Health Organization (WHO) |
| Sector | Public |
| Country | Global |
| Start | 03/2018 |
| End | 12/2018 |
| Description | Model development for the draft WHO global report on insecticide resistance in malaria vectors |
| Amount | £258,706 (GBP) |
| Organisation | IVCC |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 02/2020 |
| Description | Modeling Anorectal HIV Transmission in Women |
| Amount | £288,589 (GBP) |
| Funding ID | 5R01AI057020 Sub#201224310-05 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 11/2014 |
| End | 05/2019 |
| Description | Modelling antimalarial target product profiles for reducing P. falciparum malaria transmission |
| Amount | £316,782 (GBP) |
| Funding ID | PO14/00561 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 10/2013 |
| End | 02/2019 |
| Description | Modelling in support of India program , development and use of new tools and programmatic prioritization |
| Amount | £247,862 (GBP) |
| Funding ID | OPP1205227 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2018 |
| End | 10/2020 |
| Description | Modelling the Elimination of Onchocerciasis in Cameroon (International Exchanges) |
| Amount | £11,999 (GBP) |
| Funding ID | IES/R2/181017 |
| Organisation | The Royal Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2018 |
| End | 12/2020 |
| Description | Modelling the Value of Vaccines in Reducing the Burden of Antimicrobial Resistance |
| Amount | £53,674 (GBP) |
| Funding ID | OPP1190803 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 06/2019 |
| End | 04/2020 |
| Description | Modelling the potential impact of intermittent preventive treatment of malaria in pregnancy on antimalarial drug resistance |
| Amount | £99,998 (GBP) |
| Funding ID | ch160084 |
| Organisation | Royal Society of Medicine |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2016 |
| End | 08/2018 |
| Description | Modelling the spatiotemporal dynamics of arbovirus transmission: implications for disease control and elimination |
| Amount | £969,469 (GBP) |
| Funding ID | 213494/Z/18/Z |
| Organisation | Sir Henry Dale Fellowships |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2019 |
| End | 08/2024 |
| Description | Multi-Level Behavioral Economics and Community Psychology Approaches to Strengthen HIV Prevention Cascades in Adolescent Girls and Young Women in East Zimbabwe |
| Amount | £1,621,588 (GBP) |
| Funding ID | 1R01MH114562-01 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 09/2017 |
| End | 07/2021 |
| Description | Multidisciplinary Studies of HIV/AIDS and Aging (R21) |
| Amount | £205,531 (GBP) |
| Funding ID | 1R21AG053093 - 01 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 09/2016 |
| End | 07/2019 |
| Description | NIHR Senior Investigator Award |
| Amount | £120,000 (GBP) |
| Funding ID | P/O 427921 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2009 |
| End | 04/2021 |
| Description | NIHR: NIHR HPRU in Modelling Methodology |
| Amount | £4,234,300 (GBP) |
| Funding ID | HPRU-2012-10080 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 03/2020 |
| Description | NTD Consortium - CIFF Project |
| Amount | £184,212 (GBP) |
| Funding ID | MA4501202974 |
| Organisation | Children's Investment Fund Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2015 |
| End | 04/2018 |
| Description | NTD Consortium Renewal (STH, Schisto, Oncho) |
| Amount | £770,936 (GBP) |
| Funding ID | 1708CR001/VP1 (OPP1184344) |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2017 |
| End | 02/2021 |
| Description | Near-Infrared Spectroscopy: A One-Stop-Shop for Mosquito Epidemiological Monitoring? |
| Amount | £643,683 (GBP) |
| Funding ID | MR/P01111X/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 02/2020 |
| Description | New Data and Models to Track Progress Towards Reducing New HIV Infections |
| Amount | £861,803 (GBP) |
| Funding ID | OPP1190661 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 05/2018 |
| End | 03/2022 |
| Description | Newton Fund Researcher Links Grant |
| Amount | £34,450 (GBP) |
| Funding ID | 2016-RLWK7-10289 |
| Organisation | British Council |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 01/2018 |
| Description | Optimal spatial scales for deployment of multiple first line therapies for malaria |
| Amount | £105,750 (GBP) |
| Funding ID | RGF\EA180225 |
| Organisation | Royal Society of Medicine |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2017 |
| End | 03/2021 |
| Description | Pete Winskill Fellowship |
| Amount | £197,958 (GBP) |
| Organisation | Imperial College London |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2018 |
| End | 09/2022 |
| Description | Phase variable epigenetic regulation in Firmicutes |
| Amount | £298,700 (GBP) |
| Funding ID | RM33G0360 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 12/2018 |
| Description | Population Effects of Antretroviral Therapy to Reduce HIV Transmission (PopART) - Health Economics |
| Amount | £502,745 (GBP) |
| Funding ID | PO15001410 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 06/2015 |
| End | 01/2020 |
| Description | Population Effects of Antretroviral Therapy to Reduce HIV Transmission (PopART) - Health Economics |
| Amount | £12,709 (GBP) |
| Organisation | UK Department for International Development |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2015 |
| End | 03/2018 |
| Description | Predicting the impact of insecticide resistance and new paradigms of vector control |
| Amount | £161,331 (GBP) |
| Organisation | IVCC |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2015 |
| End | 05/2018 |
| Description | Predicting the impact of seasonal respiratory infection on temporal dynamics and characteristics of admission rates and time spent in hospital |
| Amount | £115,260 (GBP) |
| Funding ID | RDA02 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 10/2020 |
| Description | Predicting the public health impact of SSM-VIMT Phase III and IV trials |
| Amount | £19,617,788 (GBP) |
| Organisation | Malaria GIA Reference Center - PATH MVI |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 12/2019 |
| Description | Priority Setting for UHC (transfer from NICE) |
| Amount | £222,478 (GBP) |
| Funding ID | 2017 AVH |
| Organisation | Rockefeller Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 10/2016 |
| End | 12/2018 |
| Description | Progestin-based contraceptive modeling in high DMPA-IM use and high HIV incidence settings |
| Amount | £378,999 (GBP) |
| Funding ID | OPP1194416 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 09/2018 |
| End | 07/2020 |
| Description | Projections on eliminating NTDs (integrating mapping with modelling) |
| Amount | £73,998 (GBP) |
| Funding ID | OPP1156227 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2016 |
| End | 10/2018 |
| Description | Projections on eliminating NTDs (integrating mapping with modelling). |
| Amount | £20,392 (GBP) |
| Funding ID | CRR00140 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2017 |
| End | 12/2019 |
| Description | Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections (2018-2019) |
| Amount | £480,563 (GBP) |
| Funding ID | 2017/778519 |
| Organisation | Joint United Nations Programme on HIV/AIDS (UNAIDS) |
| Sector | Public |
| Country | Global |
| Start | 01/2018 |
| End | 12/2019 |
| Description | Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections (2018-2019) |
| Amount | £480,563 (GBP) |
| Funding ID | 2017/778519 |
| Organisation | Joint United Nations Programme on HIV/AIDS (UNAIDS) |
| Sector | Public |
| Country | Global |
| Start | 01/2018 |
| End | 12/2019 |
| Description | Quantifying Spatial Representativeness and Uncertainty in Antenatal Care Sentinel Surveillance for HIV in Sub-Saharan Africa. |
| Amount | $53,375 (USD) |
| Funding ID | 1R03AI125001-01A1 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 12/2016 |
| End | 11/2018 |
| Description | Quantifying and preparing for the non-communicable disease burden in the ageing HIV-positive population in Kenya |
| Amount | £134,891 (GBP) |
| Funding ID | OISE-17-62962-1 |
| Organisation | United States President's Emergency Plan for AIDS Relief |
| Sector | Public |
| Country | United States |
| Start | 08/2017 |
| End | 09/2019 |
| Description | R01 Statistical Models for Estimating and Projecting HIV/AIDS Epidemics |
| Amount | £25,290 (GBP) |
| Funding ID | 5776-ICS-DHHS-6664 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 09/2017 |
| End | 08/2019 |
| Description | Research and Development of Reconstructing HIV Epidemics from HIV Phylogenetics |
| Amount | £72,683 (GBP) |
| Funding ID | Ref: 340798 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 06/2018 |
| End | 06/2021 |
| Description | Research for Health in Conflict (R4HC): multi-sectorial capacity strengthening, partnership building and research across the MENA region |
| Amount | £432,399 (GBP) |
| Funding ID | MOTEAAR |
| Organisation | Kings BRC |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2017 |
| End | 12/2021 |
| Description | Respiratory Infection Health Protection Research Unit |
| Amount | £93,377 (GBP) |
| Funding ID | IS-HPU-1112-10064 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 03/2020 |
| Description | RooPfs (Can improved housing provide additional protection against clinical malaria over current best practice? A household-randomised controlled trial) |
| Amount | £179,101 (GBP) |
| Funding ID | RF020305 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2014 |
| End | 10/2019 |
| Description | Royal Society Laboratory Refurbishment Award |
| Amount | £188,326 (GBP) |
| Organisation | The Royal Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 08/2017 |
| Description | Schisto Vaccine project extn via NTD Modelling Consortium, Warwick |
| Amount | £121,248 (GBP) |
| Funding ID | OPP1176780 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 09/2017 |
| End | 03/2019 |
| Description | Sources and Impact of Misclassification Errors in HIV Rapid Testing Algorithms in a Hyper-Endemic HIV Setting in sub-Saharan Africa |
| Amount | £886,781 (GBP) |
| Funding ID | OPP1131208 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 07/2015 |
| End | 09/2019 |
| Description | Spread of antimicrobial resistance in Guyana: A pilot study of private supply and demand side factors |
| Amount | £26,570 (GBP) |
| Organisation | United Kingdom Research and Innovation |
| Department | Global Challenges Research Fund |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2019 |
| End | 07/2020 |
| Description | TB Modelling and Analysis Consortium |
| Amount | £37,133 (GBP) |
| Funding ID | EPIDZJ6210/Imperial |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 01/2018 |
| End | 06/2019 |
| Description | Thanzi La Onse -Frameworks and analysis to ensure value-for-money health care: developing theory, changing practices in low- and middle-income settings. |
| Amount | £687,266 (GBP) |
| Funding ID | R18664 |
| Organisation | Research Councils UK (RCUK) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2017 |
| End | 12/2021 |
| Description | The delay-care cascade and its implications for TB transmission: a study in three country settings |
| Amount | £125,031 (GBP) |
| Organisation | Stop TB Partnership |
| Sector | Charity/Non Profit |
| Country | Switzerland |
| Start | 08/2017 |
| End | 12/2018 |
| Description | The development of an Alzheimer's disease clinical trial simulator, parameter estimation from international patient cohorts and standardizing epidemiological measurement platforms for cohort studies |
| Amount | £775,501 (GBP) |
| Funding ID | HQR00720 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2019 |
| End | 06/2020 |
| Description | The evolution of influenza virus; Studies of within host and between host evolution to improve pandemic risk assessment and vaccine updates |
| Amount | £1,269,464 (GBP) |
| Funding ID | 200187/Z/15/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2016 |
| End | 03/2020 |
| Description | The evolutionary dynamics of multiazole resistance in pathogenic Aspergillus fungi |
| Amount | £427,006 (GBP) |
| Funding ID | NE/P001165/1 |
| Organisation | Natural Environment Research Council |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2016 |
| End | 04/2020 |
| Description | The farm environment: an overlooked reservoir of Mycobacterium bovis? |
| Amount | £21,364 (GBP) |
| Funding ID | RLFEW3022 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 05/2019 |
| Description | The life course of human immune responses to influenza infection and vaccination |
| Amount | £1,882,747 (GBP) |
| Funding ID | 200861/Z/16/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 01/2021 |
| Description | Tracking the flow of malaria parasites and drug resistance within the DRC and across its borders |
| Amount | £264,838 (GBP) |
| Funding ID | 00001346 |
| Organisation | National Institute of Allergy and Infectious Diseases (NIAID) |
| Sector | Public |
| Country | United States |
| Start | 11/2018 |
| End | 05/2023 |
| Description | Understanding links between microbial communities and emerging fungal pathogens in complex ecosystems |
| Amount | £394,290 (GBP) |
| Funding ID | NE/S000844/1 |
| Organisation | Natural Environment Research Council |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 10/2021 |
| Description | Unravelling and predicting the spatiotemporal structure of infectious disease outbreaks |
| Amount | £99,995 (GBP) |
| Funding ID | SBF004/1080 |
| Organisation | Academy of Medical Sciences (AMS) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2019 |
| End | 03/2021 |
| Description | Validation of New Technologies for Diagnostic Evaluation of Tuberculosis (VANTDET) |
| Amount | £1,212,037 (GBP) |
| Funding ID | 12/65/27 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 12/2017 |
| Description | Zika: A fast new intervention and an innovative method of evaluation |
| Amount | £34,518 (GBP) |
| Funding ID | AID-OAA-F-16-00094 |
| Organisation | United States Agency for International Development |
| Sector | Public |
| Country | United States |
| Start | 10/2016 |
| End | 09/2019 |
| Description | iDSI 2 (DFID Supplement) |
| Amount | £1,494,209 (GBP) |
| Funding ID | OPP1134345 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 04/2017 |
| End | 03/2020 |
| Title | Development of an individual based model for stochastic simulations of onchocerciasis |
| Description | Individual host model incorporating complex life cycle in humans and vectors to investigate interventions against human onchocerciasis that may require targeting of individuals and/or age sex groups |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | This research tool is now being used for; business case for macrofilaricides, development of clinical trial simulators, epidemiological impact of moxidectin, assessment of anti-Wolbachia drugs for the treatment of filariases. |
| URL | https://www.ncbi.nlm.nih.gov/pubmed/?term=hamley%2C+basanez |
| Title | Development of clinical trial simulators to guide clinical development of macrofilaricides |
| Description | Collaboration with Drugs for Neglected Diseases Initiative (Geneva) Adaptation of a stochastic simulation model of transmission to mimic characteristics of clinical trials to help assess; optimal sample sizes, optimal interim and end points, demonstrate superiority or non-inferiority of novel drugs in comparison with current therapies |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | Not known yet Paper under review in Nature Communications |
| Title | HPCs-integrated formulations |
| Description | Generic core and expanded formulations of HIV prevention cascades for use in tracking progress with implementation of efficacious methods of HIV prevention including combination HIV prevention. The core cascade is applied to a population at a given risk of HIV infection and comprises three steps - motivation to use the method(s), accessibility of the method(s), and effective use of the method(s). The core cascade can be used for high-level monitoring and advocacy. The expanded formulation adds factors that can contribute to drop-offs between the main steps in the core cascade which can aid identification of time- and place-specifically appropriate interventions to increase the level of effective use. These cascades can be used in mathematical models to measure the impact of current levels of use of HIV prevention methods on on HIV incidence and evaluate the potential impact of alternative interventions targeted at the different steps in the cascade (i.e. to improve motivation, accessibility and/or effective use). |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | This work contributed to a decision by UNAIDS to adopt HIV prevention cascades as an international framework for tracking progress with implementing primary methods of HIV prevention and to produce international guidelines for countries on formulations to use and methods of measurement. |
| Title | HPCs-questionnaire |
| Description | Questionnaire comprising questions to measure and interpret HIV prevention cascades for male and female condoms, pre-exposure prophylaxis, voluntary medical male circumcision, sexual partner reduction and combination HIV prevention in general population surveys. |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | None as yet - the tool is currently being piloted in a large population survey in east Zimbabwe |
| Title | RDTs-smartphone camera app |
| Description | Smartphone camera application developed by our collaborators on the study on HIV misclassification errors (Global Solutions for Infectious Diseases) to collect and transmit images of the outputs from HIV rapid tests used in routine health services - thereby enabling evaluation by external experts of the quality of outputs from these tests and the accuracy of interpretation of these outputs by local clinic staff. |
| Type Of Material | Physiological assessment or outcome measure |
| Year Produced | 2016 |
| Provided To Others? | No |
| Impact | The tool has enabled us to establish that approximately 50% of false-negative HIV test results occurring in routine health services in Zimbabwe could be due to errors by local clinic staff in reading or recording the outputs from HIV rapid tests. |
| Title | YZ-UHP! survey management portal |
| Description | Portal showing progress with conducting general population surveys on use of HIV prevention methods. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | Improvements in tracking progress against targets and errors/inconsistencies in the data requiring investigation and correction resulting in improved data completeness and quality. |
| Title | A dynamic power-law sexual network model of gonorrhoea outbreaks |
| Description | Generates a dynamic power-law sexual network |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | Impacts not yet recognised |
| URL | https://github.com/lwhittles/simdynet |
| Title | All-India TB Model |
| Description | Model developed in collaboration with India National TB Programme, combining the best available epidemiological and surveillance data to capture India's TB epidemic on a national level. The model now forms the basis for different modelling analyses, conducted by the group, relating to TB in India. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Model is currently being used to help inform India Government on strategic priorities for TB control in the country Updated 2020: model is applied by Indian government for their updated national strategic plan |
| Title | Creation and analysis of clinical trial databases |
| Description | DW3, Gates funded clinical trail for control of soil transmitted helminths. Tumikia - Gates funder clinical trial for control of soil transmitted helminths Geshiyaro - CIFF funded clinical trial for control of schistosomiasis and soil transmitted helminths |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Sophisticated analysis of data and scientific publications |
| Title | Data from: Effect of culling on individual badger Meles meles behaviour: potential implications for bovine tuberculosis transmission |
| Description | 1. Culling wildlife as a form of disease management can have unexpected and sometimes counterproductive outcomes. In the UK, badgers (Meles meles) are culled in efforts to reduce badger-to-cattle transmission of Mycobacterium bovis, the causative agent of bovine tuberculosis (TB). However, culling has previously been associated with both increased and decreased incidence of M. bovis infection in cattle. 2. The adverse effects of culling have been linked to cull-induced changes in badger ranging, but such changes are not well documented at the individual level. Using GPS-collars, we characterised individual badger behaviour within an area subjected to widespread industry-led culling, comparing it with the same area before culling and with three unculled areas. 3. Culling was associated with a 61% increase (95% CI 27-103%) in monthly home range size, a 39% increase (95% CI 28-51%) in nightly maximum distance from the sett, and a 17% increase (95% CI 11-24%) in displacement between successive GPS-collar locations recorded at 20-minute intervals. Despite travelling further, we found a 91.2 minute (95% CI 67.1-115.3 minute) reduction in the nightly activity time of individual badgers associated with culling. These changes became apparent while culls were ongoing and persisted after culling ended. 4. Expanded ranging in culled areas was associated with individual badgers visiting 45% (95% CI 15-80%) more fields each month, suggesting that surviving individuals had the opportunity to contact more cattle. Moreover, surviving badgers showed a 19.9-fold increase (95% CI 10.8-36.4 increase) in the odds of trespassing into neighbouring group territories, increasing opportunities for intergroup contact. 5. Synthesis and Applications: Badger culling was associated with behavioural changes among surviving badgers which potentially increased opportunities for both badger-to-badger and badger-to-cattle transmission of M. bovis. Furthermore, by reducing the time badgers spent active, culling may have reduced badgers' accessibility to shooters, potentially undermining subsequent population control efforts. Our results specifically illustrate the challenges posed by badger behaviour to cull-based TB control strategies and furthermore, they highlight the negative impacts culling can have on integrated disease control strategies. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Title | Develop statistical methods for determining whether a cases of malaria was acquired in the country of detection or imported from abroad. |
| Description | Develop a Bayesian method of taking a persons travel history, details of malaria endemicity and seasonality of transmission and determining the percentage likelihood that the case of malaria was: (1) acquired at home, (2) imported from abroad, (3) imported from another region of the country (4) was of unknown origin. |
| Type Of Material | Data analysis technique |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | None as yet |
| Title | EPP-ASM model for estimation HIV epidemic trends |
| Description | The EPP-ASM model is a new demographic-structured model for estimating HIV epidemic trends in sub-Saharan Africa. Compared to previously existing tools, the new model better captures the demographic impacts of the HIV epidemic and improves estimates of recent HIV incidence trends in generalised epidemic settings. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | - Model implemented in 2019 version of Spectrum software (v5.73) supported by UNAIDS for global HIV estimates and projections in developed in 2019 (to be published June 2019). - Model and software code utilised for HIV estimation by the Global Burden of Disease study by the Institute for Health Metrics and Evaluation |
| URL | https://github.com/mrc-ide/eppasm |
| Title | Experiments for detection of Plasmodium berghei infected Anopheles stephensi mosquitoes using near-infrared spectroscopy |
| Description | Spectra from uninfected, indected and infectious mosquitoes |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | None currently |
| URL | https://doi.org/10.5281/zenodo.1001720 |
| Title | Fluscape project dataset |
| Description | Serological data from a study in China |
| Type Of Material | Database/Collection of data |
| Year Produced | 2015 |
| Provided To Others? | Yes |
| Impact | None yet |
| URL | http://www.fluscape.org |
| Title | HPV and HIV vaccination model |
| Description | Mathematical model of HIV and HPV transmission to assess HPV vaccination and screening programme for cervical cancer elimination in South Africa. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | Development is still ongoing. As a result of development, funding was received from WHO to carry out further modelling analysis to provide guidance for the vaccination and screening programmes to reach cervical cancer elimination in countries with high HIV prevalence. |
| Title | HSV2 - HIV Model |
| Description | Mathematical model designed to estimate the contribution of HSV2 to HIV transmission and impact of HSV2 vaccination globally |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | Resulted in publications that will inform WHO business investment case for development of HSV2 vaccine |
| Title | Harvard Consortium for the creation of an international Alzheimer's database |
| Description | Drawing together of multiple longitudinal cohort databases |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | Publications in 'Brain', 'Neuroscience' and 'Lancet' |
| Title | Household survey in Eastern Zimbawe |
| Description | Conducting a household survey in Eastern Zimbawe to determine HIV risks as part of a 20 year old study. See Manicaland HIV project (.org) |
| Type Of Material | Database/Collection of data |
| Year Produced | 2007 |
| Provided To Others? | No |
| Impact | This has been going on since 2007 and it is on-going |
| Title | International risk of disease spread due to air travel |
| Description | Model to establish the number of exported cases due to air travel during an outbreak. This has been applied to Zika, Yellow Fever and COVID-19. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Model has been used to inform US CDC on the risk of importation of Yellow Fever from Brazil Model is used to advise on the need of travel restrictions and role of travellers vaccinations. Paper published in 2019 in Scientific Reports. |
| URL | https://www.nature.com/articles/s41598-019-56521-9 |
| Title | MARDY - Antifiungal Resistance Database |
| Description | Online database of anti fungal resistance alleles for multiple fungal pathogens |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Published in 2018 |
| URL | http://mardy.dide.ic.ac.uk |
| Title | Malaria socio-economic data |
| Description | qualitative and quantitative data from several West African countries on perceptions of quality, risk, costs and cost effectiveness |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | Too early to identify impacts |
| Title | Manicaland - HPCs |
| Description | SQL database comprising data from the baseline general population survey for a study to measure and interpret HIV prevention cascades and to evaluate the impact of novel behavioural economics and community psychology interventions to strengthen these cascades in adolescent girls and young women and their male partners. The database includes HIV infection data obtained from provider-initiated HIV testing and counselling (PITC) and, for those who decline PITC, from laboratory tests conducted using dried blood spots collected in the survey. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | None as yet - data collection still in progress |
| Title | Manicaland - cohort |
| Description | SQL database comprising data from 6 rounds of a general population cohort survey in Manicaland, east Zimbabwe, with linked HIV test results |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | Data describing and interpreting declines in HIV prevalence, HIV incidence and AIDS mortality within the general population over the period 1998 to 2013. Results have been published in more than 200 scientific papers including Science and The Lancet. The findings from the study led to our being requested by UNAIDS to conduct in-depth investigations into the existence and causes of national HIV decline in Zimbabwe. |
| Title | Manicaland - test & treat |
| Description | Database containing data extracted from routine programme records at health centres in three districts of Manicaland province for the periods 6 months prior to and 6 months following the introduction of the 'treat all' policy for people living with HIV infection. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | None as yet. This database was compiled by a PhD student. Papers are currently being drafted for publication. |
| Title | Methodology for spatial mapping |
| Description | Developed two new statistical approaches. One now underpins the local burden of disease project at IHME |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | Model results used widely for policy. |
| Title | Molecular Markers of Anti-malaria Partner Drug Resistence |
| Description | Systematic review of mutations in Pfmdr1 |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | None yet |
| URL | https://gh.bmj.com/content/3/5/e000999 |
| Title | Multi-locus negative frequency dependent selection model |
| Description | This model describes the multi-locus negative frequency dependent selection model of bacterial population evolution. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | This model was described in the original publication (Corander et al 2017 Nat. Ecol. Evol. 1:1950-1960), and has subsequently been used to optimise vaccine designs as a part of current work-in-progress. |
| URL | https://github.com/nickjcroucher/multilocusNFDS/ |
| Title | Research database on schistosomiasis and soil-transmitted helminthiases |
| Description | The schistosomiasis and soil-transmitted helminthiases (STHs) research theme aims to pool and make available Individual Patient Data (IPD) from all available studies to address knowledge gaps and improve treatment outcomes for people affected by these diseases. By amalgamating and standardising available individual patient data, the utility of existing resources can be maximised to address priority questions on the treatment of schistosomiasis and STHs, to create a framework to prospectively assemble future studies, to guide the design of future studies, and to make research progress more efficient. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | No impacts known yet |
| URL | https://www.iddo.org/research-themes/schistosomiasis-sths |
| Title | Review of the effectiveness of indoor spraying of insecticide for control of malaria |
| Description | Systematic review of experimental hut trial data |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Not known yet |
| Title | Serosolver R package |
| Description | This R package allows other scientists to investigate the life course of infection of an individual with influenza strains by using serological data from different historical strains gathered at different time points. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| Impact | It is being used by other members of the scientific community to support research |
| URL | https://github.com/seroanalytics/serosolver |
| Title | Systematic collation of coronavirus cases Internationally and in mainland China |
| Description | Collation fo publically available data from government sources ad media to reconstruct linelist of cases for cases detected outside of China Daily updated case numbers across 33 provinces in China |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | No |
| Impact | Used in COVID-19 response and publciation in MRC reports. |
| Title | Systematic review of key parameters for the WHO R&D priority pathogens |
| Description | Systematic review of key parameters required for mathematical modelling and outbreak analytics for the 9 pathogens identified by WHO as high potential to cause epidemics. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | Not yet recognised, though used to support COVID-19 analysis. |
| Title | Website for snakebite research (VenBank) |
| Description | Interactive web portal for global snakebite epidemiological study |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | none yet (beta testing) |
| URL | https://venbank.info/ |
| Title | Within-host evolution model |
| Description | Compartmental model of within-host recombination between bacteria. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | This model was the basis of the publication Croucher et al. (2016) PLoS Biol. 14(3):e1002394. |
| URL | https://github.com/nickjcroucher/mgeTransformation |
| Description | ALPHA Network |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provision of data from Manicaland, Zimbabwe for use in pooled and comparative analyses of trends and determinants of HIV incidence in sub-Saharan African countries with generalised epidemics in the post-antiretroviral treatment era. Contributions to analyses of the pooled and site-specific data. |
| Collaborator Contribution | The ALPHA Network coordinated by researchers at the LSHTM sourced funding from BMGF for the project, are designing the data analyses to be conducted in the project, and will be organising data analysis workshops and results dissemination activities for the project. |
| Impact | No outputs as yet |
| Start Year | 2019 |
| Description | Alzheimers Disease Epidemiology Research Group (ADERG) |
| Organisation | Erasmus University Rotterdam |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | expertise, intellectual input and the training of staff |
| Collaborator Contribution | expertise, intellectual input and the training of staff, access to data, equipment and facilities. |
| Impact | Scientific publucations |
| Start Year | 2017 |
| Description | Alzheimers Disease Epidemiology Research Group (ADERG) |
| Organisation | MRC Dementias Platform UK |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | expertise, intellectual input and the training of staff |
| Collaborator Contribution | expertise, intellectual input and the training of staff, access to data, equipment and facilities. |
| Impact | Scientific publucations |
| Start Year | 2017 |
| Description | Alzheimers Disease Epidemiology Research Group (ADERG) |
| Organisation | University of Gothenburg |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | expertise, intellectual input and the training of staff |
| Collaborator Contribution | expertise, intellectual input and the training of staff, access to data, equipment and facilities. |
| Impact | Scientific publucations |
| Start Year | 2017 |
| Description | Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network |
| Organisation | Africa Health Research Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa. |
| Collaborator Contribution | - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites |
| Impact | - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO |
| Start Year | 2013 |
| Description | Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network |
| Organisation | Biomedical Research and Training Institute (BRTI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa. |
| Collaborator Contribution | - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites |
| Impact | - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO |
| Start Year | 2013 |
| Description | Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network |
| Organisation | Kenyan Institute for Medical Research (KEMRI) |
| Country | Kenya |
| Sector | Public |
| PI Contribution | - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa. |
| Collaborator Contribution | - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites |
| Impact | - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO |
| Start Year | 2013 |
| Description | Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Department | Alpha Network |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa. |
| Collaborator Contribution | - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites |
| Impact | - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO |
| Start Year | 2013 |
| Description | Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Department | Department of Population Health |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa. |
| Collaborator Contribution | - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites |
| Impact | - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO |
| Start Year | 2013 |
| Description | Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network |
| Organisation | MRC/UVRI Uganda Research Unit on AIDS |
| Country | Uganda |
| Sector | Public |
| PI Contribution | - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa. |
| Collaborator Contribution | - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites |
| Impact | - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO |
| Start Year | 2013 |
| Description | Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network |
| Organisation | Rakai Health Sciences Program |
| Country | Uganda |
| Sector | Public |
| PI Contribution | - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa. |
| Collaborator Contribution | - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites |
| Impact | - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO |
| Start Year | 2013 |
| Description | Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network |
| Organisation | University of the Witwatersrand |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa. |
| Collaborator Contribution | - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites |
| Impact | - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO |
| Start Year | 2013 |
| Description | Avian influenza in wild african penguins |
| Organisation | University of Pretoria |
| Department | Faculty of Veterinary Science |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Statistical and epidemiological design, analysis and interpretation |
| Collaborator Contribution | Provide veterinary expertise Data collection Diagnostic analysis Provide ecological expertise |
| Impact | None reported yet |
| Start Year | 2019 |
| Description | Baylor School of Medicine (Sasirekha Ramani) |
| Organisation | Baylor School |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Lead coordinator on a study and design of clinical study design |
| Collaborator Contribution | Rotavirus virology |
| Impact | Not yet |
| Start Year | 2016 |
| Description | Behaviour and bovine TB |
| Organisation | Cardiff University |
| Department | School of Geography and Planning |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Statistical analysis |
| Collaborator Contribution | Behavioural science expertise |
| Impact | Publication in Vaccine |
| Start Year | 2019 |
| Description | Biomedical Research and Training Institute, Zimbawe |
| Organisation | Biomedical Research and Training Institute (BRTI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Provide Analysis |
| Collaborator Contribution | They provide fieldwork |
| Impact | Awarded a grant with Simon Gregson: Multi-Level Behavioral Economics and Community Psychology Approaches to Strengthen HIV Prevention Cascades in Adolescent Girls and Young Women in East Zimbabwe. |
| Start Year | 2017 |
| Description | Bristol University |
| Organisation | University of Bristol |
| Department | Proteomics Facility |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Modelling, data analysis |
| Collaborator Contribution | Economic analysis and modelling. Supervision of researchers. |
| Impact | Publications on the impact of the Avahan intervention in India. On-going HIV projects funded by linkages. A collaboration HSV 2 vaccination. |
| Description | CDC Outbreak |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Country | United States |
| Sector | Public |
| PI Contribution | Developing rapid methodologies for analysis of fungal disease outbreaks |
| Collaborator Contribution | Methodological and technological advances |
| Impact | Ongoing manuscript preparation |
| Start Year | 2014 |
| Description | Capacity building for research in conflict |
| Organisation | King's College London |
| Department | Fondation Peters, King's College London |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Co-Principle Investigators on the project on capacity building for research in conflict. |
| Collaborator Contribution | Co-Principle Investigators on the project on capacity building for research in conflict. |
| Impact | Papers currently in draft. |
| Start Year | 2018 |
| Description | Capacity building for research in conflict |
| Organisation | University of Cambridge |
| Department | Cambridge Neuroscience |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-Principle Investigators on the project on capacity building for research in conflict. |
| Collaborator Contribution | Co-Principle Investigators on the project on capacity building for research in conflict. |
| Impact | Papers currently in draft. |
| Start Year | 2018 |
| Description | Central TB Division, Ministry of Health, Government of India |
| Organisation | Indian Ministry of Health |
| Country | India |
| Sector | Public |
| PI Contribution | Ongoing work with Central TB Division to develop a modelling framework that can help them prioritise their TB control efforts across the country |
| Collaborator Contribution | Developing the analytical framework in collaboration with national TB programme; coordinating with the programme to ensure that the model is maximally applicable; subcontracting additional analytical support from relevant experts in India |
| Impact | Work ongoing |
| Start Year | 2018 |
| Description | Centre for Infectious Disease Research Zambia |
| Organisation | Centre for Infectious Disease Research in Zambia |
| Country | Zambia |
| Sector | Charity/Non Profit |
| PI Contribution | Study design and lab support for a rotavirus study |
| Collaborator Contribution | Running a clinical trial of rotavirus vaccine in Zambia |
| Impact | Successful application for "Human infection challenge vaccine (HIC-vac) network" with Roma Chilengi |
| Start Year | 2018 |
| Description | Cervical Cancer Elimination |
| Organisation | Harvard University |
| Department | Harvard Medical School |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Mathematical modelling expertise and systematic reviews of epidemiological studies |
| Collaborator Contribution | WHO - co-ordinating meetings and leading the initiative. Defining guidelines and co-ordinating media response Harvard University - Modelling analysis Laval - Modelling analysis and providing guidance McGill - Modelling analysis and providing guidance |
| Impact | Numerous publications Informing WHO guidelines for cervical cancer elimination globally Media coverage |
| Start Year | 2018 |
| Description | Cervical Cancer Elimination |
| Organisation | McGill University |
| Department | Department of Epidemiology, Biostatistics and Occupational Health |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Mathematical modelling expertise and systematic reviews of epidemiological studies |
| Collaborator Contribution | WHO - co-ordinating meetings and leading the initiative. Defining guidelines and co-ordinating media response Harvard University - Modelling analysis Laval - Modelling analysis and providing guidance McGill - Modelling analysis and providing guidance |
| Impact | Numerous publications Informing WHO guidelines for cervical cancer elimination globally Media coverage |
| Start Year | 2018 |
| Description | Cervical Cancer Elimination |
| Organisation | University Hospital of Laval University |
| Country | Canada |
| Sector | Hospitals |
| PI Contribution | Mathematical modelling expertise and systematic reviews of epidemiological studies |
| Collaborator Contribution | WHO - co-ordinating meetings and leading the initiative. Defining guidelines and co-ordinating media response Harvard University - Modelling analysis Laval - Modelling analysis and providing guidance McGill - Modelling analysis and providing guidance |
| Impact | Numerous publications Informing WHO guidelines for cervical cancer elimination globally Media coverage |
| Start Year | 2018 |
| Description | Cervical Cancer Elimination |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | Mathematical modelling expertise and systematic reviews of epidemiological studies |
| Collaborator Contribution | WHO - co-ordinating meetings and leading the initiative. Defining guidelines and co-ordinating media response Harvard University - Modelling analysis Laval - Modelling analysis and providing guidance McGill - Modelling analysis and providing guidance |
| Impact | Numerous publications Informing WHO guidelines for cervical cancer elimination globally Media coverage |
| Start Year | 2018 |
| Description | Collaboration with Natashia Morris, Health GIS Centre, MRC South Africa |
| Organisation | Medical Research Council of South Africa (MRC) |
| Country | South Africa |
| Sector | Public |
| PI Contribution | We have been in discussions with Dr Natashia Morris the Manager Health GIS Centre about how to determine whether a case of malaria identified by routine surveillance was contracted in country or imported from abroad. We have presented our methods and Dr Morris is looking to put into place systems which would allow the probability that a case of malaria was imported to be calculated instead of dichotomous decisions based on personal opinion. |
| Collaborator Contribution | Provided information on data collected by the South African national malaria control programme and other countries in the E8 Partnership. |
| Impact | None as yet. |
| Start Year | 2018 |
| Description | Consolidated guidelines on HIV testing services for a changing epidemic |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | - Mathematical modelling of new algorithms and strategies for HIV diagnosis. |
| Collaborator Contribution | - Technical leadership and oversight, production of normative guidance. |
| Impact | - Revised 2019 WHO Consolidated Guidelines on HIV Testing Services - Policy brief: Consolidated guidelines on HIV testing services for a changing epidemic - Policy brief: WHO encourages countries to adapt HIV testing strategies in response to changing epidemic |
| Start Year | 2018 |
| Description | Consultancy to develop guidelines for National Malaria Programmes for stratification, prioritisation and optimised resource allocation within strategic planning |
| Organisation | World Health Organization (WHO) |
| Department | Global Malaria Programme |
| Country | Switzerland |
| Sector | Charity/Non Profit |
| PI Contribution | I am developing a document for National Malaria Programmes for stratification, prioritisation and optimised resource allocation within strategic planning as part of a wider drive to use routine malaria surveillance data for operational action. |
| Collaborator Contribution | WHO is providing consultancy pay as well as general guidance and feedback |
| Impact | No outputs to date. |
| Start Year | 2019 |
| Description | DFID Ebola Situational Reports |
| Organisation | Government of the UK |
| Department | Department for International Development (DfID) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | We have continued to share reports of the analysis of the ongoing Ebola outbreak in the Democratic Republic of the Congo. This has included projections of future incidence, bed demand, and vaccine demand estimates. |
| Collaborator Contribution | Context for analysis needs e.g. requirements for vaccine demand. |
| Impact | Reports for internal use at DFID and White Hall. |
| Start Year | 2018 |
| Description | DeWorm3 |
| Organisation | Natural History Museum |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Intellectual input, expertise and the training of staff. |
| Collaborator Contribution | Intellectual input, expertise and the training of staff. |
| Impact | Scientific journal publications in PLoS NTDs, Epidemics, Journal of Theoretical Biology, Lancet and Parasites and Vectors |
| Start Year | 2016 |
| Description | DeWorm3 |
| Organisation | University of Washington |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Intellectual input, expertise and the training of staff. |
| Collaborator Contribution | Intellectual input, expertise and the training of staff. |
| Impact | Scientific journal publications in PLoS NTDs, Epidemics, Journal of Theoretical Biology, Lancet and Parasites and Vectors |
| Start Year | 2016 |
| Description | Detection and Management of Ivermectin Resistance |
| Organisation | McGill University |
| Department | Institute of Parasitology |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Mahematical modelling; preparation of papers; successful preparation of grant proposals |
| Collaborator Contribution | Data on genetic analysis of filarial parasites (lymphatic filariasis, onchocerciasis) for mathematical modelling of the evolution and spread of anthelmintic resistance |
| Impact | Outputs in the form of publications: PubMed ID numbers: 19805362; 19154624; 18382607; 17320006; 16834821. Outcomes in the form of invitations to speak at scientific meetings (Am Soc Trop Med Hyg, December 2008; Royal Society UK-Ghana collaboration, April 2008), and Expert Groups (WHO/World Bank, January 2008). Impacts in the form of invitation to belong to the Disease Reference Group on Helminths, World Health Organization. |
| Description | Development of Clinical Trial Simulators for Macrofilaricidal Drugs for the Control of Filariases |
| Organisation | Drugs for Neglected Diseases initiative (DNDi) |
| Country | Switzerland |
| Sector | Charity/Non Profit |
| PI Contribution | Development of clinical trial modelling simulators (paper in preparation) |
| Collaborator Contribution | Meetings to discuss coordination of project |
| Impact | Presentations to the Bill & Melinda Gates Foundation, American Society of Tropical Medicine and Hygiene, paper in preparation |
| Start Year | 2016 |
| Description | Development of a viral kinetic model for Dengue infection |
| Organisation | Johnson & Johnson |
| Department | Janssen Pharmaceuticals |
| Country | United States |
| Sector | Private |
| PI Contribution | The aim of the Project is to develop a viral kinetics model for dengue infection in different species that enables evaluating the impact of a prophylactic intervention and/or therapeutic treatment on dengue infection. The goal is to build a viral kinetics model that has the potential to be translatable between species (mice - non-human primates (NHP) - human). The viral kinetics model will be used to gain more insight in the mechanism of action of the direct anti-viral drug candidates and to inform various stages of the drug development process, e.g. in determining different dosing regimens for upcoming studies. The hands-on modeling will be performed by an employee (post-doctoral research fellow) of the UNIVERSITY and a Global Clinical Pharmacology scientist of JANSSEN internally, under the supervision and scientific guidance from the Dengue development team, employees of Quantitative Sciences within JANSSEN, and appropriate representatives of the UNIVERSITY. |
| Collaborator Contribution | The hands-on modeling will be performed by an employee (post-doctoral research fellow) of the UNIVERSITY and a Global Clinical Pharmacology scientist of JANSSEN internally, under the supervision and scientific guidance from the Dengue development team, employees of Quantitative Sciences within JANSSEN, and appropriate representatives of the UNIVERSITY. |
| Impact | N/A at this stage. |
| Start Year | 2019 |
| Description | District-level HIV estimation and HIV resource allocation in South Africa |
| Organisation | Government of South Africa |
| Department | Department of Health |
| Country | South Africa |
| Sector | Public |
| PI Contribution | - Statistical modelling of HIV surveillance and program data |
| Collaborator Contribution | - Curation of survey and programme data. - Interpretation and implementation of estimates. |
| Impact | - Official HIV estimates and targets for South Africa HIV programme |
| Start Year | 2019 |
| Description | District-level HIV estimation and HIV resource allocation in South Africa |
| Organisation | Human Sciences Research Council (HSRC) |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | - Statistical modelling of HIV surveillance and program data |
| Collaborator Contribution | - Curation of survey and programme data. - Interpretation and implementation of estimates. |
| Impact | - Official HIV estimates and targets for South Africa HIV programme |
| Start Year | 2019 |
| Description | District-level HIV estimation and HIV resource allocation in South Africa |
| Organisation | University of Cape Town |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | - Statistical modelling of HIV surveillance and program data |
| Collaborator Contribution | - Curation of survey and programme data. - Interpretation and implementation of estimates. |
| Impact | - Official HIV estimates and targets for South Africa HIV programme |
| Start Year | 2019 |
| Description | District-level HIV estimation and HIV resource allocation in South Africa |
| Organisation | Wits Health Consortium |
| Country | South Africa |
| Sector | Private |
| PI Contribution | - Statistical modelling of HIV surveillance and program data |
| Collaborator Contribution | - Curation of survey and programme data. - Interpretation and implementation of estimates. |
| Impact | - Official HIV estimates and targets for South Africa HIV programme |
| Start Year | 2019 |
| Description | Dr. Kounbobr Roch Dabiré of IRSS (Burkina Faso) |
| Organisation | Research Institute for Health Sciences (IRSS) |
| Country | Burkina Faso |
| Sector | Public |
| PI Contribution | We have provided training in the use of spectroscopy and the alalytical methods needed to interpret the results. |
| Collaborator Contribution | Dr Dabiré leads a research team which is extending the methods we have developed to mosquito vectors of malaria in Africa. |
| Impact | Project meeting in London (UK) and Bobo Dioulasso (Burkina Faso). |
| Start Year | 2017 |
| Description | EIT Cross KIC Education 2018 - Challenge Based Learning |
| Organisation | Sorbonne University |
| Country | France |
| Sector | Academic/University |
| PI Contribution | co-PI |
| Collaborator Contribution | co-PIs |
| Impact | Climate change and Health MOOC: https://www.futurelearn.com/courses/climate-change-public-health |
| Start Year | 2018 |
| Description | EIT Cross KIC Education 2018 - Challenge Based Learning |
| Organisation | University of Grenoble |
| Country | France |
| Sector | Academic/University |
| PI Contribution | co-PI |
| Collaborator Contribution | co-PIs |
| Impact | Climate change and Health MOOC: https://www.futurelearn.com/courses/climate-change-public-health |
| Start Year | 2018 |
| Description | EIT Cross KIC Education 2018 - Challenge Based Learning |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | co-PI |
| Collaborator Contribution | co-PIs |
| Impact | Climate change and Health MOOC: https://www.futurelearn.com/courses/climate-change-public-health |
| Start Year | 2018 |
| Description | Epidemiology and Control of Cystic Echinococcosis in Peru |
| Organisation | National University of Río Negro |
| Country | Argentina |
| Sector | Academic/University |
| PI Contribution | Participation in and presentations at Newton Fund Workshop in Lima, September 2018 Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey |
| Collaborator Contribution | Convening and organisation of Newton Fund Workshop Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey |
| Impact | Multidisciplinary collaboration: epidemiologists, veterinarians, parasitologists, mathematical modellers |
| Start Year | 2018 |
| Description | Epidemiology and Control of Cystic Echinococcosis in Peru |
| Organisation | National University of San Marcos |
| Country | Peru |
| Sector | Academic/University |
| PI Contribution | Participation in and presentations at Newton Fund Workshop in Lima, September 2018 Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey |
| Collaborator Contribution | Convening and organisation of Newton Fund Workshop Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey |
| Impact | Multidisciplinary collaboration: epidemiologists, veterinarians, parasitologists, mathematical modellers |
| Start Year | 2018 |
| Description | Epidemiology and Control of Cystic Echinococcosis in Peru |
| Organisation | University of Surrey |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Participation in and presentations at Newton Fund Workshop in Lima, September 2018 Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey |
| Collaborator Contribution | Convening and organisation of Newton Fund Workshop Updated February 2020: Joint supervision of MSc Epidemiology student at Imperial College London and external supervision of a PhD student at the University of Surrey |
| Impact | Multidisciplinary collaboration: epidemiologists, veterinarians, parasitologists, mathematical modellers |
| Start Year | 2018 |
| Description | Epidemiology and Control of Schistosomiasis and Soil-Transmitted Helminthiasis |
| Organisation | University of Cambridge |
| Department | University of Cambridge, BBSRC IGF Drosophila Genomics Facility |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Supervision of PhD students, in UK (together with the Schistosomiasis Control Initiative and the Royal Veterinary College) and Australia, for the analysis of data and preparation of joint publications |
| Collaborator Contribution | Sharing of parasitological and epidemiological data pre- and post-implementation of control interventions based on anthelmintic chemotherapy in Africa for joint analysis through shared students |
| Impact | Publications in peer-review journals |
| Description | Epidemiology and Control of Schistosomiasis and Soil-Transmitted Helminthiasis |
| Organisation | University of Queensland |
| Department | University of Queensland Diamantina Institute |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Supervision of PhD students, in UK (together with the Schistosomiasis Control Initiative and the Royal Veterinary College) and Australia, for the analysis of data and preparation of joint publications |
| Collaborator Contribution | Sharing of parasitological and epidemiological data pre- and post-implementation of control interventions based on anthelmintic chemotherapy in Africa for joint analysis through shared students |
| Impact | Publications in peer-review journals |
| Description | Epidemiology and Control of Taeniasis/Cysticercosis |
| Organisation | Government of Madagascar |
| Country | Madagascar |
| Sector | Public |
| PI Contribution | Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts |
| Collaborator Contribution | Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030. |
| Impact | Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports |
| Start Year | 2017 |
| Description | Epidemiology and Control of Taeniasis/Cysticercosis |
| Organisation | Imperial College London |
| Department | Schistosomiasis Control Initiative (SCI) |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts |
| Collaborator Contribution | Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030. |
| Impact | Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports |
| Start Year | 2017 |
| Description | Epidemiology and Control of Taeniasis/Cysticercosis |
| Organisation | Institute of Tropical Medicine Antwerp |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts |
| Collaborator Contribution | Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030. |
| Impact | Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports |
| Start Year | 2017 |
| Description | Epidemiology and Control of Taeniasis/Cysticercosis |
| Organisation | Royal Veterinary College (RVC) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts |
| Collaborator Contribution | Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030. |
| Impact | Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports |
| Start Year | 2017 |
| Description | Epidemiology and Control of Taeniasis/Cysticercosis |
| Organisation | Technical University of Munich |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts |
| Collaborator Contribution | Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030. |
| Impact | Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports |
| Start Year | 2017 |
| Description | Epidemiology and Control of Taeniasis/Cysticercosis |
| Organisation | The Statens Serum Institute (SSI) |
| Country | Denmark |
| Sector | Public |
| PI Contribution | Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts |
| Collaborator Contribution | Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030. |
| Impact | Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports |
| Start Year | 2017 |
| Description | Epidemiology and Control of Taeniasis/Cysticercosis |
| Organisation | University of Ghent |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019 Updated January 2020 - Workshop occured 26-27 April 2019 at Imperial College London. Paper published in Bulletin of the WHO as a result of workshop. Preparation of joint manuscripts |
| Collaborator Contribution | Preparation of joint manuscripts Updated January 2020 Contribution to preparation of joint presentation to the WHO meeting in April 2019 as part of the consultation for setting the new road map for NTDs for 2021-2030. |
| Impact | Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation. Updated February 2020: Publications in Bulletin of WHO, Open Gates Research Paper under review in Scientific Reports |
| Start Year | 2017 |
| Description | Epidemiology of Onchocerciasis and Loiasis in Central Africa |
| Organisation | University of Montpellier |
| Country | France |
| Sector | Academic/University |
| PI Contribution | Preparation of joint publications and research proposals that have been successfully funded (e.g. Royal Society) |
| Collaborator Contribution | Sharing of data for joint analysis of parasitological and epidemiological features of infections caused by Onchocerca volvulus and Loa loa |
| Impact | Publications in peer-review journals; reports for World Health Organization (on Alternative Treatment Strategies for onchocerciasis). See also presence in London Centre for Neglected Tropical Disease Research: https://www.londonntd.org/research/projects-search/developing-models-of-loiasis-transmission-to-inform-control-of-the-disease |
| Description | Epidemiology of Onchocerciasis and Loiasis in Central Africa |
| Organisation | University of Yaoundé |
| Country | Cameroon |
| Sector | Academic/University |
| PI Contribution | Preparation of joint publications and research proposals that have been successfully funded (e.g. Royal Society) |
| Collaborator Contribution | Sharing of data for joint analysis of parasitological and epidemiological features of infections caused by Onchocerca volvulus and Loa loa |
| Impact | Publications in peer-review journals; reports for World Health Organization (on Alternative Treatment Strategies for onchocerciasis). See also presence in London Centre for Neglected Tropical Disease Research: https://www.londonntd.org/research/projects-search/developing-models-of-loiasis-transmission-to-inform-control-of-the-disease |
| Description | Ethics in universal health coverage |
| Organisation | University of Stellenbosch |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Principle investigator for the research project on ethics in universal health coverage. |
| Collaborator Contribution | Co-principle investigator for the research project on ethics in universal health coverage. |
| Impact | Conference presentations, publications in process. |
| Start Year | 2018 |
| Description | Ethics in universal health coverage |
| Organisation | University of the Witwatersrand |
| Department | Wits Reproductive Health and HIV Institute |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Principle investigator for the research project on ethics in universal health coverage. |
| Collaborator Contribution | Co-principle investigator for the research project on ethics in universal health coverage. |
| Impact | Conference presentations, publications in process. |
| Start Year | 2018 |
| Description | Floyd Dowell of United States Department of Agriculture |
| Organisation | U.S. Department of Agriculture USDA |
| Department | Agricultural Research Service |
| Country | United States |
| Sector | Public |
| PI Contribution | We have developed new analytical methods to understand how mosquito age, species and infection status (with the malaria parasite) changes the light being measured by a spectrometer |
| Collaborator Contribution | Dr Dowell is a Research Agricultural Engineer who has pioneered work using Near Infrared Spectroscopy to investigate the age of mosquitoes. Dr Dowell provided training and technical advice to scientists from Imperial College London and our partners |
| Impact | Training of UK, Burkinabe and Australian Scientists in the use of spectrometer |
| Start Year | 2017 |
| Description | FluScape |
| Organisation | Johns Hopkins University |
| Department | Johns Hopkins Bloomberg School of Public Health |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | We run an epidemiological study in Southern China. At imperial we manage the field site and conduct mathematical and statistical analysis. |
| Collaborator Contribution | Johns Hopkins manage the information systems and also conduct mathematical and statistical analysis. |
| Impact | Any paper with Cummings as a co-author. |
| Start Year | 2008 |
| Description | Foundation for Innovative New Diagnostics |
| Organisation | Foundation for Innovative New Diagnostics (FIND) |
| Country | Switzerland |
| Sector | Charity/Non Profit |
| PI Contribution | Contributing modelling analysis in support of WHO recommendations for new diagnostic tools for tuberculosis |
| Collaborator Contribution | Developing a modelling framework to project the potential impact of new diagnostic tools being supported by FIND, on the TB epidemic in settings such as South Africa. The work will be used to inform new WHO guidelines. |
| Impact | Work ongoing |
| Start Year | 2018 |
| Description | Future preventive therapy regimens for TB |
| Organisation | Aurum Institute |
| Country | South Africa |
| Sector | Charity/Non Profit |
| PI Contribution | Modelling analysis in support of new WHO guidelines for target profiles of future regimens |
| Collaborator Contribution | Providing data and inputs for the modelling |
| Impact | New target product profiles from WHO currently in preparation - will incorporate modelling Manuscript pending |
| Start Year | 2019 |
| Description | Future preventive therapy regimens for TB |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | Modelling analysis in support of new WHO guidelines for target profiles of future regimens |
| Collaborator Contribution | Providing data and inputs for the modelling |
| Impact | New target product profiles from WHO currently in preparation - will incorporate modelling Manuscript pending |
| Start Year | 2019 |
| Description | Gagandeep Kang-Christian Medical College |
| Organisation | Christian Medical College, Vellore |
| Country | India |
| Sector | Academic/University |
| PI Contribution | Gastrointestinal Sciences. Statistical, epidemiological and mathematical analysis |
| Collaborator Contribution | Clinical studies, immunological analysis |
| Impact | multiple publications, grant renewal in 2020 |
| Start Year | 2010 |
| Description | Geshiaro |
| Organisation | Ethiopian Public Health Institute |
| Country | Ethiopia |
| Sector | Public |
| PI Contribution | expertise, intellectual input and the training of staff |
| Collaborator Contribution | expertise, intellectual input and the training of staff, access to data, equipment and facilities |
| Impact | No outputs yet. |
| Start Year | 2018 |
| Description | Geshiaro |
| Organisation | Ministry of Health, Ethiopia |
| Country | Ethiopia |
| Sector | Public |
| PI Contribution | expertise, intellectual input and the training of staff |
| Collaborator Contribution | expertise, intellectual input and the training of staff, access to data, equipment and facilities |
| Impact | No outputs yet. |
| Start Year | 2018 |
| Description | Geshiaro |
| Organisation | Simprints |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | expertise, intellectual input and the training of staff |
| Collaborator Contribution | expertise, intellectual input and the training of staff, access to data, equipment and facilities |
| Impact | No outputs yet. |
| Start Year | 2018 |
| Description | Geshiaro |
| Organisation | World Vision Ethiopia |
| Country | Ethiopia |
| Sector | Public |
| PI Contribution | expertise, intellectual input and the training of staff |
| Collaborator Contribution | expertise, intellectual input and the training of staff, access to data, equipment and facilities |
| Impact | No outputs yet. |
| Start Year | 2018 |
| Description | Geshiyaro project (clinical trial) |
| Organisation | Ethiopian Public Health Institute |
| Country | Ethiopia |
| Sector | Public |
| PI Contribution | Design of trial Monitoring and evaluation of progress |
| Collaborator Contribution | Implementers of NTD treatments Partners in Monitoring and Evaluation |
| Impact | Publication on protocol of trial in 'Parasites and Vectors' in October 2019 |
| Start Year | 2019 |
| Description | Global Burden of disease |
| Organisation | Institute for Health Metrics and Evaluation (IHME) |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Provided algorithms for the local burden of disease project |
| Collaborator Contribution | Publications (3 in nature 1 in the New England Journal of Medicine, 1 in Lancet) |
| Impact | Publications (3 in nature 1 in the New England Journal of Medicine, 1 in Lancet) |
| Start Year | 2016 |
| Description | Greg Devine at QIMR Berghofer (Brisbane, Australia) |
| Organisation | QIMR Berghofer Medical Research Institute |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Provide funding to run experiments in Australia on local Aedes mosquito populations |
| Collaborator Contribution | Partner running experiments in Australia on local Aedes mosquito populations |
| Impact | None yet |
| Start Year | 2017 |
| Description | HIV DREAMS evaluation |
| Organisation | United States Department of State |
| Department | Office of the Global AIDS Coordinator |
| Country | United States |
| Sector | Public |
| PI Contribution | Samir Bhatt's group worked with OGAC to estimate the rate of change of new diagnoses among pregnant women. |
| Collaborator Contribution | Technical expertise in data preparation |
| Impact | Samir Bhatt produced the modelled estimates that were used by OGAC in their world AIDS day report. The announcement was made by Amb Birx in December 2019. |
| Start Year | 2016 |
| Description | HIV Preventation Trial Network |
| Organisation | Fred Hutchinson Cancer Research Center (FHCRC) |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | A collaborative centre that develops and uses mathematical models to support HPTN research activities and inform research directions. We collaborate with: Statistical Centre for HIV/AIDS Research and Prevention. |
| Collaborator Contribution | See above |
| Impact | See publications, presentations and workshops on https://hptnmodelling.org/resources/ |
| Start Year | 2014 |
| Description | HIV Prevention Trial Network Modelling Centre |
| Organisation | Fred Hutchinson Cancer Research Center (FHCRC) |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Lead on Mathematical modelling to inform and complement research activities of the HPTN. Conduct mathematical modelling and computer simulation studies anchored to the best available data to support and inform HPTN research activities and directions with the overarching aim to combat the HIV/AIDS epidemic more efficiently |
| Collaborator Contribution | Lead of statistical centre who is funding the HPTN modelling centre. Provide data and statistical expertise, conduct trials that provide data for mathematical modelling. |
| Impact | A number of publications: https://hptnmodelling.org/resources/?resourcetype=publications Multidisciplinary - epidemiology, mathematical modelling, statistics, clinical research |
| Start Year | 2013 |
| Description | HIV prevention cascades |
| Organisation | Bill and Melinda Gates Foundation |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications. |
| Collaborator Contribution | The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas. |
| Impact | UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health |
| Start Year | 2015 |
| Description | HIV prevention cascades |
| Organisation | Biomedical Research and Training Institute (BRTI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications. |
| Collaborator Contribution | The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas. |
| Impact | UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health |
| Start Year | 2015 |
| Description | HIV prevention cascades |
| Organisation | Joint United Nations Programme on HIV/AIDS (UNAIDS) |
| Country | Global |
| Sector | Public |
| PI Contribution | Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications. |
| Collaborator Contribution | The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas. |
| Impact | UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health |
| Start Year | 2015 |
| Description | HIV prevention cascades |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications. |
| Collaborator Contribution | The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas. |
| Impact | UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health |
| Start Year | 2015 |
| Description | HIV prevention cascades |
| Organisation | Ministry of Health and Child Welfare of the Republic of Zimbabwe |
| Country | Zimbabwe |
| Sector | Public |
| PI Contribution | Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications. |
| Collaborator Contribution | The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas. |
| Impact | UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health |
| Start Year | 2015 |
| Description | HIV prevention cascades |
| Organisation | Population Services International |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications. |
| Collaborator Contribution | The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas. |
| Impact | UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health |
| Start Year | 2015 |
| Description | HIV rapid test misclassification errors |
| Organisation | Biomedical Research and Training Institute (BRTI) |
| Country | Zimbabwe |
| Sector | Charity/Non Profit |
| PI Contribution | Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing. |
| Collaborator Contribution | The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study |
| Impact | Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology |
| Start Year | 2015 |
| Description | HIV rapid test misclassification errors |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Country | United States |
| Sector | Public |
| PI Contribution | Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing. |
| Collaborator Contribution | The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study |
| Impact | Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology |
| Start Year | 2015 |
| Description | HIV rapid test misclassification errors |
| Organisation | Global Solutions for Infectious Disease |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing. |
| Collaborator Contribution | The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study |
| Impact | Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology |
| Start Year | 2015 |
| Description | HIV rapid test misclassification errors |
| Organisation | Ministry of Health and Child Welfare of the Republic of Zimbabwe |
| Country | Zimbabwe |
| Sector | Public |
| PI Contribution | Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing. |
| Collaborator Contribution | The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study |
| Impact | Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology |
| Start Year | 2015 |
| Description | HIV rapid test misclassification errors |
| Organisation | Roehampton University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing. |
| Collaborator Contribution | The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study |
| Impact | Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology |
| Start Year | 2015 |
| Description | HIV rapid test misclassification errors |
| Organisation | University of Copenhagen |
| Department | Department of Public Health |
| Country | Denmark |
| Sector | Academic/University |
| PI Contribution | Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing. |
| Collaborator Contribution | The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study |
| Impact | Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology |
| Start Year | 2015 |
| Description | HPRU Modelling |
| Organisation | Public Health England |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | I am a theme lead for the HPRU in Modelling Methodology held by Neil Ferguson. |
| Collaborator Contribution | Marc Baguelin (co-I for this MRC grant) is also a theme lead. |
| Impact | None yet. |
| Start Year | 2014 |
| Description | HPRU Respiratory Infections |
| Organisation | Public Health England |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | I am a theme lead for Respiratory infections and will help to supervise staff at Imperial and PHE. |
| Collaborator Contribution | They will also co supervise staff and helped to write the grant. |
| Impact | None yet. |
| Start Year | 2014 |
| Description | HSV2 vaccine |
| Organisation | Joint United Nations Programme on HIV/AIDS (UNAIDS) |
| Country | Global |
| Sector | Public |
| PI Contribution | Mathematical Modelling expertise and modelling analysis |
| Collaborator Contribution | Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews |
| Impact | Publications to come |
| Start Year | 2019 |
| Description | HSV2 vaccine |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Mathematical Modelling expertise and modelling analysis |
| Collaborator Contribution | Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews |
| Impact | Publications to come |
| Start Year | 2019 |
| Description | HSV2 vaccine |
| Organisation | Oswaldo Cruz Foundation (Fiocruz) |
| Country | Brazil |
| Sector | Public |
| PI Contribution | Mathematical Modelling expertise and modelling analysis |
| Collaborator Contribution | Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews |
| Impact | Publications to come |
| Start Year | 2019 |
| Description | HSV2 vaccine |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Mathematical Modelling expertise and modelling analysis |
| Collaborator Contribution | Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews |
| Impact | Publications to come |
| Start Year | 2019 |
| Description | HSV2 vaccine |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | Mathematical Modelling expertise and modelling analysis |
| Collaborator Contribution | Bristol - mathematical modelling and epidemiological review Fiocruz - assisting with access to data UNAIDs - provided data for analysis WHO - leading the coordination of project. Building a business case for development of HSV2 vaccine. Provide scientific input and guidance LSHTM - provide guidance and assist with systematic reviews |
| Impact | Publications to come |
| Start Year | 2019 |
| Description | How can modelling contribute to achieving the goals for Chagas disease in the horizon 2020 and beyond? |
| Organisation | Pan American Health Organization |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Development of a data platform for collation and curation of Chagas disease epidemiological data Development of force of infection models for Chagas disease Contribution to papers on Chagas disease modelling |
| Collaborator Contribution | Princeton: Contribution of expertise in mathematical modelling Sussex: Contribution of machine learning methods PAHO: Funding of in country workshops and person based in Washington dedicated to systematic reviews, data entry and liaising with endemic countries |
| Impact | Publication of papers in Clinical Infectious Diseases, BMJ Global Health Attendance to WHO meeting in Geneva in April 2019 to help assess through modelling, the feasibility of the WHO proposed goals for Chagas disease, 2021- 2030 Preparation of a Gates Open Research open letter |
| Start Year | 2018 |
| Description | How can modelling contribute to achieving the goals for Chagas disease in the horizon 2020 and beyond? |
| Organisation | Princeton University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Development of a data platform for collation and curation of Chagas disease epidemiological data Development of force of infection models for Chagas disease Contribution to papers on Chagas disease modelling |
| Collaborator Contribution | Princeton: Contribution of expertise in mathematical modelling Sussex: Contribution of machine learning methods PAHO: Funding of in country workshops and person based in Washington dedicated to systematic reviews, data entry and liaising with endemic countries |
| Impact | Publication of papers in Clinical Infectious Diseases, BMJ Global Health Attendance to WHO meeting in Geneva in April 2019 to help assess through modelling, the feasibility of the WHO proposed goals for Chagas disease, 2021- 2030 Preparation of a Gates Open Research open letter |
| Start Year | 2018 |
| Description | How can modelling contribute to achieving the goals for Chagas disease in the horizon 2020 and beyond? |
| Organisation | University of Sussex |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Development of a data platform for collation and curation of Chagas disease epidemiological data Development of force of infection models for Chagas disease Contribution to papers on Chagas disease modelling |
| Collaborator Contribution | Princeton: Contribution of expertise in mathematical modelling Sussex: Contribution of machine learning methods PAHO: Funding of in country workshops and person based in Washington dedicated to systematic reviews, data entry and liaising with endemic countries |
| Impact | Publication of papers in Clinical Infectious Diseases, BMJ Global Health Attendance to WHO meeting in Geneva in April 2019 to help assess through modelling, the feasibility of the WHO proposed goals for Chagas disease, 2021- 2030 Preparation of a Gates Open Research open letter |
| Start Year | 2018 |
| Description | IMPPACT: Maximising the public health impact of interventions to control malaria in pregnancy |
| Organisation | Liverpool School of Tropical Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | To generate modelling and mapping of optimal preventative strategies for the prevention of malaria in pregnancy. These results were presented at Regional meetings of national policymakers in West and East Africa in Togo and Kenya respectively. |
| Collaborator Contribution | Other partners were responsible for organising meetings, developing stakeholder interviews and translating results from recent trials into other policy-relevant recommendations and outputs. |
| Impact | Multi-disciplinary: Modelling, Qualitative and Quantitive research, health economics and policy-making Regional meetings in Togo and Kenya Publication in PLoS Medicine and further publication pending. |
| Start Year | 2015 |
| Description | IMPPACT: Maximising the public health impact of interventions to control malaria in pregnancy |
| Organisation | Sixth Framework Programme (FP6) |
| Department | European and Developing Countries Clinical Trials Partnership |
| Country | Netherlands |
| Sector | Public |
| PI Contribution | To generate modelling and mapping of optimal preventative strategies for the prevention of malaria in pregnancy. These results were presented at Regional meetings of national policymakers in West and East Africa in Togo and Kenya respectively. |
| Collaborator Contribution | Other partners were responsible for organising meetings, developing stakeholder interviews and translating results from recent trials into other policy-relevant recommendations and outputs. |
| Impact | Multi-disciplinary: Modelling, Qualitative and Quantitive research, health economics and policy-making Regional meetings in Togo and Kenya Publication in PLoS Medicine and further publication pending. |
| Start Year | 2015 |
| Description | Information on a novel malaria transmission blocking vaccine candidate |
| Organisation | National Institutes of Health (NIH) |
| Department | Vaccine Research Center (VRC) |
| Country | United States |
| Sector | Public |
| PI Contribution | We are using mathematical models to predict the effectiveness of a novel vaccine candidate when used in a small scale field trial and in a wider mass distribution campaign. |
| Collaborator Contribution | Provide details on the vaccine candidate including its efficacy and duration of protection. |
| Impact | Predictive models that can support sample size calculations to adequately power studies. |
| Start Year | 2019 |
| Description | Integrating genomic surveillance and ecological modelling to maximise pneumococcal vaccine efficacy |
| Organisation | Public Health England |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Providing expertise in mathematical modelling and genomic epidemiology. |
| Collaborator Contribution | Genome sequencing, sharing of data and expertise in epidemiology and vaccinology. |
| Impact | No outputs yet. |
| Start Year | 2019 |
| Description | Javier Martin (Dr) -NIBSC |
| Organisation | National Institute for Biological Standards and Control (NIBSC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Sequencing and analysis of polio virus in environmental samples |
| Collaborator Contribution | Virus isolation and sequencing |
| Impact | A supplement to the existing grant and a new grant |
| Start Year | 2017 |
| Description | Jinan University |
| Organisation | Jinan University |
| Country | China |
| Sector | Academic/University |
| PI Contribution | We will provide samples and analysis and Jinan will conduct immunological assays |
| Collaborator Contribution | We will provide samples and analysis and Jinan will conduct immunological assays |
| Impact | None yet |
| Start Year | 2016 |
| Description | Kenya National Aid Control Council - Dr Nduku Kilonzo - Preparing for the double burden HIV |
| Organisation | Kenya National Malaria Control Programme |
| Country | Kenya |
| Sector | Public |
| PI Contribution | Tim Hallett leads the research to inform policy |
| Collaborator Contribution | Partners run the programme in Kenya |
| Impact | A grant was obtained in 2017 and it is still active. Publication of 2 manuscripts in BMJ Global Health and CID |
| Start Year | 2014 |
| Description | Laval University |
| Organisation | University Hospital of Laval University |
| Country | Canada |
| Sector | Hospitals |
| PI Contribution | Collaborating with two teams lead by Michel Alary (HIV) and Marc Brisson (HPV Vaccination). I provide expetise in Modelling Statistical Analysis and Epidemiological expertise at the intersection between HIV and HPV. |
| Collaborator Contribution | Michel Alary provides the epidemiological expertise and Marc Brisson provides modelling in health economic expertise. |
| Impact | Multiple Publications and successful grant applications. |
| Description | London Centre for NTD Research |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration |
| Collaborator Contribution | expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration |
| Impact | Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations. |
| Start Year | 2013 |
| Description | London Centre for NTD Research |
| Organisation | Natural History Museum |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration |
| Collaborator Contribution | expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration |
| Impact | Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations. |
| Start Year | 2013 |
| Description | London Centre for NTD Research |
| Organisation | Royal Veterinary College (RVC) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration |
| Collaborator Contribution | expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration |
| Impact | Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations. |
| Start Year | 2013 |
| Description | London Centre for NTD Research |
| Organisation | The Wellcome Trust Sanger Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration |
| Collaborator Contribution | expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration |
| Impact | Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations. |
| Start Year | 2013 |
| Description | MIT Broad Institute |
| Organisation | Broad Institute |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Contribution of whole genome sequences of Cryptococcus neoformans, analysis and experimental data |
| Collaborator Contribution | Contribution of whole genome sequences of Cryptococcus neoformans and analysis. |
| Impact | Paper in submission |
| Start Year | 2012 |
| Description | MRC Centre for Global Health Analysis - "Breaking silos and building collaborations for integrated and sustainable management of cholangiocarcinoma and its causal pathogen Opisthorchis viverrini in LMICs in the Lower Mekong Region |
| Organisation | Global Health Asia Institute |
| Country | Thailand |
| Sector | Charity/Non Profit |
| PI Contribution | PI |
| Collaborator Contribution | co-I |
| Impact | none yet |
| Start Year | 2018 |
| Description | MRC Centre for Global Health Analysis - "Breaking silos and building collaborations for integrated and sustainable management of cholangiocarcinoma and its causal pathogen Opisthorchis viverrini in LMICs in the Lower Mekong Region |
| Organisation | International Agency for Research on Cancer (IARC) |
| Country | France |
| Sector | Academic/University |
| PI Contribution | PI |
| Collaborator Contribution | co-I |
| Impact | none yet |
| Start Year | 2018 |
| Description | MRC Centre for Global Health Analysis - "Breaking silos and building collaborations for integrated and sustainable management of cholangiocarcinoma and its causal pathogen Opisthorchis viverrini in LMICs in the Lower Mekong Region |
| Organisation | Phramongkutklao College of Medicine |
| Country | Thailand |
| Sector | Academic/University |
| PI Contribution | PI |
| Collaborator Contribution | co-I |
| Impact | none yet |
| Start Year | 2018 |
| Description | MRC Dementias Collaboration |
| Organisation | MRC Dementias Platform UK |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Creation of clinical trial simulator for possible therapies for Alzheimer's New methods for analysis of epidemiological data for Alzheimer's disease progression |
| Collaborator Contribution | Clincial, Statistical and Epidemiological input |
| Impact | Publications in scientific journals |
| Start Year | 2019 |
| Description | Malaria in Pregnancy |
| Organisation | Liverpool School of Tropical Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | This collaboration involves estimating the burden of malaria in pregnancy, its relationship with transmission and the impact of interventions. I provide mathematical modelling expertise, data analysis to questions relevant to these issues. |
| Collaborator Contribution | Members of the Malaria in Pregnancy Consortium Secretariat provide support for these analyses in terms of providing access to data and academic support and input. As well as providing funding for travel to meetings. |
| Impact | I developed the first model of malaria in pregnancy (Walker et al, Nature Communications 2012) and its link to transmission and using this was able to develop the first map of potential low birth weight burden attributable to malaria (Walker et al, Lancet Global Health 2014). I am also part of a working group looking at the incremental impact of switching to a policy of testing pregnant women for malaria and treating them if infected (Incremental Screening and Treatment) relative to treating them presumptively which will provide scientific support to an Evidence Review Group which will report to the Malaria Policy Advisory Committee of the World Health Organisation about the potential area of application of this strategy. I provided a preliminary version of this analysis during a Malaria in Pregnancy symposium at ASTMH 2014 in New Orleans. Research from this collaboration was also presented at the Evidence Review Group meeting into Intermittent screening and treatment in pregnancy and the safety of ACTs in the first trimester at WHO in Geneva in July 2015 and had direct influence on WHO malaria in pregnancy policy. |
| Start Year | 2014 |
| Description | Malaria mapping and burden |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | I provided supervision and worked collaboratively to produce malaria estimates for the global burden of disease project, the WHO and the global fund. |
| Collaborator Contribution | Two subcontract grants, computational facilities, data preparation and synthesis, facility space at the Big data institute |
| Impact | 2 papers submitted to the Lancet, 1 paper accepted in Nature |
| Start Year | 2016 |
| Description | Malaria project collaborations |
| Organisation | Government of The Gambia |
| Country | Gambia |
| Sector | Public |
| PI Contribution | Guide economic work packages |
| Collaborator Contribution | co-production of research questions, data collection, analysis and dissemination |
| Impact | Papers in press and preparation |
| Description | Malaria project collaborations |
| Organisation | MURAZ Center |
| Country | Burkina Faso |
| Sector | Academic/University |
| PI Contribution | Guide economic work packages |
| Collaborator Contribution | co-production of research questions, data collection, analysis and dissemination |
| Impact | Papers in press and preparation |
| Description | Malaria project collaborations |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Unit, The Gambia |
| Country | Gambia |
| Sector | Public |
| PI Contribution | Guide economic work packages |
| Collaborator Contribution | co-production of research questions, data collection, analysis and dissemination |
| Impact | Papers in press and preparation |
| Description | Malaria project collaborations |
| Organisation | University of Bamako |
| Country | Mali |
| Sector | Academic/University |
| PI Contribution | Guide economic work packages |
| Collaborator Contribution | co-production of research questions, data collection, analysis and dissemination |
| Impact | Papers in press and preparation |
| Description | Malawi Public Health Institute |
| Organisation | Public Health Institute of Malawi |
| Country | Malawi |
| Sector | Public |
| PI Contribution | Analysis of data |
| Collaborator Contribution | Collation of data |
| Impact | Nothing to report |
| Start Year | 2018 |
| Description | Malawi/Kenya |
| Organisation | Wellcome Trust |
| Department | Malawi-Liverpool Wellcome Trust Clinical Research Programme |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | I recruited a Research Assistant from Malawi, on a UK Royal Society Global Challenges grant, in June 2017 to undertake modelling of the impact of intermittent treatment in pregnancy for malaria on drug resistance development. He worked for a year and a half working with me training in mathematical modelling. |
| Collaborator Contribution | The partner hosted our postdoc for a number of months in Malawi, provided supervision and regular phone calls to discuss the progress of the project. They are also currently undertaking large trials of intermittent preventive treatment in pregnant women, and these trials helped to inform our modelling analysis. |
| Impact | The RA recruited has now gone on to a PhD to LSHTM in the same field, which we hope will contribute to capacity building. |
| Start Year | 2016 |
| Description | Mapping housing quality |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | A collaborative project mapping housing quality in Africa |
| Collaborator Contribution | Research support, data assistance |
| Impact | 1 paper accepted in Nature (article) |
| Start Year | 2018 |
| Description | Mapping the risk of international infectious disease spread |
| Organisation | HealthMap |
| Sector | Charity/Non Profit |
| PI Contribution | Developing a mathematical model of spatial spread of infectious diseases |
| Collaborator Contribution | Providing data on Ebola |
| Impact | Talks at several conferences Papers in preparation |
| Start Year | 2016 |
| Description | Mapping the risk of international infectious disease spread |
| Organisation | Healthsites.io |
| Country | France |
| Sector | Private |
| PI Contribution | Developing a mathematical model of spatial spread of infectious diseases |
| Collaborator Contribution | Providing data on Ebola |
| Impact | Talks at several conferences Papers in preparation |
| Start Year | 2016 |
| Description | Mapping the risk of international infectious disease spread |
| Organisation | International Society for Infectious Diseases (ISID) |
| Department | Program for Monitoring Emerging Diseases |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Developing a mathematical model of spatial spread of infectious diseases |
| Collaborator Contribution | Providing data on Ebola |
| Impact | Talks at several conferences Papers in preparation |
| Start Year | 2016 |
| Description | Mapping the risk of international infectious disease spread |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Developing a mathematical model of spatial spread of infectious diseases |
| Collaborator Contribution | Providing data on Ebola |
| Impact | Talks at several conferences Papers in preparation |
| Start Year | 2016 |
| Description | Medicines for Malaria Venture |
| Organisation | Medicines for Malaria Venture (MMV) |
| Country | Switzerland |
| Sector | Charity/Non Profit |
| PI Contribution | We are using mathematical modelling to estimate the impact of both existing antimalarial drugs and also products in development on malaria transmission, and their cost-effectiveness. |
| Collaborator Contribution | Funding (research costs and 1 postdoc for 3 years), requests for research and advice on ongoing work. |
| Impact | A data collaboration with the Worldwide Antimalarial Resistance Network and Sanofi Ltd to access clinical trial data. We published three papers: Nature Communications (2017), Malaria Journal (2017) and Trends in Parasitology (2017). |
| Start Year | 2013 |
| Description | Member of Malaria Modelling Consortium |
| Organisation | Bill and Melinda Gates Foundation |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | I participated in consortium meetings, and contributed substantially to a Malaria Modelling Consortium report to the World Health Organization Malaria Policy Advisory Group on results from modelling mass drug administration for malaria control. |
| Collaborator Contribution | Other modelling partners contribute modelling results, the Gates Foundation coordinate activities, arrange meetings and fund travel for the meetings. |
| Impact | Malaria Modelling Consortium report to the World Health Organization Malaria Policy Advisory Group on results from modelling mass drug administration for malaria control. This is now published as a paper in Lancet Global Health. |
| Start Year | 2015 |
| Description | Memorandum of Understanding with National Institute of Health - Colombia |
| Organisation | Government of Colombia |
| Department | National Institute of Health, Colombia |
| Country | Colombia |
| Sector | Public |
| PI Contribution | Cooperative working and exchange of research in public health and education activities in science and technology. Overseeing study design, data analysis and write-up. |
| Collaborator Contribution | Cooperative working and exchange of research in public health and education activities in science and technology. Data sharing. |
| Impact | Kelly Charniga (PhD) funded by Imperial President Scholarship |
| Start Year | 2017 |
| Description | Miren Iturizza-Gomara (Prof-Mrs) University of Liverpool |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Microbiome analysis |
| Collaborator Contribution | Provide rotavirus |
| Impact | 1 publication BMJ Open |
| Start Year | 2018 |
| Description | Modelling West Nile Virus in Italy |
| Organisation | Edmund Mach Foundation |
| Country | Italy |
| Sector | Charity/Non Profit |
| PI Contribution | Mathematical modelling expertise |
| Collaborator Contribution | Provision of data Mathematical modelling expertise |
| Impact | 1 paper published in PLoS NTDs and one manuscript under review Conference presentations |
| Start Year | 2018 |
| Description | Modelling West Nile Virus in Italy |
| Organisation | Experimental Zooprophylactic Institute of the Venezie |
| Country | Italy |
| Sector | Public |
| PI Contribution | Mathematical modelling expertise |
| Collaborator Contribution | Provision of data Mathematical modelling expertise |
| Impact | 1 paper published in PLoS NTDs and one manuscript under review Conference presentations |
| Start Year | 2018 |
| Description | Modelling West Nile Virus in Italy |
| Organisation | Pasteur Institute, Paris |
| Country | France |
| Sector | Charity/Non Profit |
| PI Contribution | Mathematical modelling expertise |
| Collaborator Contribution | Provision of data Mathematical modelling expertise |
| Impact | 1 paper published in PLoS NTDs and one manuscript under review Conference presentations |
| Start Year | 2018 |
| Description | Modelling West Nile Virus in Italy |
| Organisation | University of Trento |
| Country | Italy |
| Sector | Academic/University |
| PI Contribution | Mathematical modelling expertise |
| Collaborator Contribution | Provision of data Mathematical modelling expertise |
| Impact | 1 paper published in PLoS NTDs and one manuscript under review Conference presentations |
| Start Year | 2018 |
| Description | Modelling and dengue vaccines |
| Organisation | Takeda Pharmaceutical Company |
| Department | Takeda Global Research & Development Centre (Europe) |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Modelling related to Dengue disease and vaccination. |
| Collaborator Contribution | Know how with regard to its therapeutic area vaccines and in particular, but limited to its Dengue, Norovirus and Polio candidate vaccines. |
| Impact | N?A at this stage. |
| Start Year | 2018 |
| Description | Modelling dengue vaccination |
| Organisation | Sanofi |
| Department | Sanofi Research Division |
| Country | France |
| Sector | Private |
| PI Contribution | Mathematical modelling of immunogenicity and efficacy data |
| Collaborator Contribution | Provision of data Contribution to mathematical modelling |
| Impact | Publication of several papers Talks at numerous conferences |
| Start Year | 2013 |
| Description | Modelling pandemic influenza in the USA |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Country | United States |
| Sector | Public |
| PI Contribution | Building model of pandemic influenza in USA to support CDC planning |
| Collaborator Contribution | Providing data and convening network of modelling |
| Impact | Ongoing |
| Start Year | 2019 |
| Description | Modelling the elimination of onchocerciasis in Cameroon |
| Organisation | Royal Veterinary College (RVC) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Joint publication in Systematic Reviews Mentoring of a PhD student from Cameroon through AIMS Cameroon for mathematical modelling Provide the mathematical and geostatistical modelling expertise |
| Collaborator Contribution | Responsible for collating and curating the data Drafting of manuscript for publication |
| Impact | Mentoring of a PhD student and modelling outcomes that will help the MoH in Cameroon to identify optimal interventions for onchocerciasis elimination |
| Start Year | 2018 |
| Description | Modelling the elimination of onchocerciasis in Cameroon |
| Organisation | University of Yaoundé |
| Country | Cameroon |
| Sector | Academic/University |
| PI Contribution | Joint publication in Systematic Reviews Mentoring of a PhD student from Cameroon through AIMS Cameroon for mathematical modelling Provide the mathematical and geostatistical modelling expertise |
| Collaborator Contribution | Responsible for collating and curating the data Drafting of manuscript for publication |
| Impact | Mentoring of a PhD student and modelling outcomes that will help the MoH in Cameroon to identify optimal interventions for onchocerciasis elimination |
| Start Year | 2018 |
| Description | Modelling the epidemiological impact of moxidectin for the control and elimination of onchocerciasis |
| Organisation | Medicines Development for Global Health |
| Country | Australia |
| Sector | Private |
| PI Contribution | Providing modelling simulations to assess the probabilities of elimination in policy relevant settings. Preparation of joint publications and posters |
| Collaborator Contribution | Provision of phase III clinical trial data for model parameterisation Provision of input throughout the collaboration |
| Impact | Preparation of FDA dossier for approval of moxidectin for human use |
| Start Year | 2017 |
| Description | Modelling to support Kenya's National Strategic Plan for TB control |
| Organisation | Ministry of Health, Kenya |
| Country | Kenya |
| Sector | Public |
| PI Contribution | Providing analysis and modelling in support of Kenya's upcoming National Strategic Plan for TB control |
| Collaborator Contribution | Kenya's new national strategic plan will be used as a model by funding agencies such as the Global Fund, for applications by other countries. The modelling component of the strategic plan plays a key role in prioritisation amongst different interventions, and the Global Fund and other donors will require that other future applications are structured in the same way. |
| Impact | Modelling input into National Strategic Plan, to be launched on World TB Day (24 Mar 2019) Work ongoing |
| Start Year | 2017 |
| Description | Modelling within host kinetics of dengue |
| Organisation | Janssen Pharmaceutica NV |
| Country | Belgium |
| Sector | Private |
| PI Contribution | Mathematical modelling expertise |
| Collaborator Contribution | Provision of data Contribution to modelling |
| Impact | Not yet recognised - collaboration ongoing |
| Start Year | 2019 |
| Description | NHIR emergency room demand |
| Organisation | Imperial College London |
| Department | NIHR/Wellcome Trust Imperial Clinical Research Facility |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Assisting St Mary hospital and Charing-cross to predict A&E patient demand. |
| Collaborator Contribution | Funding and data assistance (preparation and collection) |
| Impact | None yet |
| Start Year | 2018 |
| Description | NIH Pakistan |
| Organisation | National Institute of Health, Pakistan |
| Country | Pakistan |
| Sector | Public |
| PI Contribution | Analyse data |
| Collaborator Contribution | Work together on sequencing poliovirus circulating in Pakistan and Afghanistan |
| Impact | manuscript under review |
| Start Year | 2016 |
| Description | NIRS Queensland |
| Organisation | QIMR Berghofer Medical Research Institute |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Providing technical support and specialist knowledge |
| Collaborator Contribution | Data and field expertise |
| Impact | not known |
| Start Year | 2017 |
| Description | NTD Modelling Consortium |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | expertise, intellectual input and the training of staff |
| Collaborator Contribution | expertise, intellectual input and the training of staff, access to data. |
| Impact | Scientific publications |
| Start Year | 2015 |
| Description | NTD Modelling Consortium |
| Organisation | University of Warwick |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | expertise, intellectual input and the training of staff |
| Collaborator Contribution | expertise, intellectual input and the training of staff, access to data. |
| Impact | Scientific publications |
| Start Year | 2015 |
| Description | Naomi model for district-level HIV estimates in sub-Saharan Africa |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Country | United States |
| Sector | Public |
| PI Contribution | - Developed new model for district-level estimates of HIV prevalence, antiretroviral treatment coverage, and new HIV infections in sub-Saharan Africa. - Developed web-based software interface for district HIV estimates used by national governments in 25 sub-Saharan African countries. |
| Collaborator Contribution | - Provided technical expertise on surveillance data and statistical modelling. - Provided data inputs to modelling. - Supported implementation of software tool with national governments. |
| Impact | - District HIV estimates used for US Government PEPFAR 2020 budget allocations. - Manuscript in preparation. - District level HIV estimates to be publicly released by UNAIDS in June 2020. |
| Start Year | 2019 |
| Description | Naomi model for district-level HIV estimates in sub-Saharan Africa |
| Organisation | Joint United Nations Programme on HIV/AIDS (UNAIDS) |
| Country | Global |
| Sector | Public |
| PI Contribution | - Developed new model for district-level estimates of HIV prevalence, antiretroviral treatment coverage, and new HIV infections in sub-Saharan Africa. - Developed web-based software interface for district HIV estimates used by national governments in 25 sub-Saharan African countries. |
| Collaborator Contribution | - Provided technical expertise on surveillance data and statistical modelling. - Provided data inputs to modelling. - Supported implementation of software tool with national governments. |
| Impact | - District HIV estimates used for US Government PEPFAR 2020 budget allocations. - Manuscript in preparation. - District level HIV estimates to be publicly released by UNAIDS in June 2020. |
| Start Year | 2019 |
| Description | Naomi model for district-level HIV estimates in sub-Saharan Africa |
| Organisation | United States President's Emergency Plan for AIDS Relief |
| Country | United States |
| Sector | Public |
| PI Contribution | - Developed new model for district-level estimates of HIV prevalence, antiretroviral treatment coverage, and new HIV infections in sub-Saharan Africa. - Developed web-based software interface for district HIV estimates used by national governments in 25 sub-Saharan African countries. |
| Collaborator Contribution | - Provided technical expertise on surveillance data and statistical modelling. - Provided data inputs to modelling. - Supported implementation of software tool with national governments. |
| Impact | - District HIV estimates used for US Government PEPFAR 2020 budget allocations. - Manuscript in preparation. - District level HIV estimates to be publicly released by UNAIDS in June 2020. |
| Start Year | 2019 |
| Description | Naomi model for district-level HIV estimates in sub-Saharan Africa |
| Organisation | University of Washington |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | - Developed new model for district-level estimates of HIV prevalence, antiretroviral treatment coverage, and new HIV infections in sub-Saharan Africa. - Developed web-based software interface for district HIV estimates used by national governments in 25 sub-Saharan African countries. |
| Collaborator Contribution | - Provided technical expertise on surveillance data and statistical modelling. - Provided data inputs to modelling. - Supported implementation of software tool with national governments. |
| Impact | - District HIV estimates used for US Government PEPFAR 2020 budget allocations. - Manuscript in preparation. - District level HIV estimates to be publicly released by UNAIDS in June 2020. |
| Start Year | 2019 |
| Description | Novel candidate vaccine for Schistoma mansoni |
| Organisation | Bill and Melinda Gates Foundation |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Design on end points and potential impact of vaccine in resource poor settings |
| Collaborator Contribution | Implementation of the pilot experiments in animal models and phase I trials in humans |
| Impact | Successful trials in baboons. Imperial team helped analyse trial data |
| Start Year | 2019 |
| Description | Novel candidate vaccine for Schistoma mansoni |
| Organisation | National Institutes of Health (NIH) |
| Country | United States |
| Sector | Public |
| PI Contribution | Design on end points and potential impact of vaccine in resource poor settings |
| Collaborator Contribution | Implementation of the pilot experiments in animal models and phase I trials in humans |
| Impact | Successful trials in baboons. Imperial team helped analyse trial data |
| Start Year | 2019 |
| Description | PATH Innovation Collaboration - ANC-based surveillance tool |
| Organisation | Kenyan Institute for Medical Research (KEMRI) |
| Department | KEMRI/CDC Research and Public Health Collaboration |
| Country | Kenya |
| Sector | Charity/Non Profit |
| PI Contribution | I am developing a statistical model using routine testing data from antenatal clinics in Western Kenya to estimate malaria transmission within the general population |
| Collaborator Contribution | In-country collaborators PATH, Kenya Medical Research Institute and the US CDC are responsible for collecting, collating and providing the data, as well as organising dissemination workshops. |
| Impact | A dissemination meeting took place in Kisumu in August 2018. |
| Start Year | 2016 |
| Description | PATH Innovation Collaboration - ANC-based surveillance tool |
| Organisation | Program for Appropriate Technology in Health (PATH) |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | I am developing a statistical model using routine testing data from antenatal clinics in Western Kenya to estimate malaria transmission within the general population |
| Collaborator Contribution | In-country collaborators PATH, Kenya Medical Research Institute and the US CDC are responsible for collecting, collating and providing the data, as well as organising dissemination workshops. |
| Impact | A dissemination meeting took place in Kisumu in August 2018. |
| Start Year | 2016 |
| Description | PATH to pilot novel bednet in pilot intervention trials |
| Organisation | PATH |
| Country | Global |
| Sector | Charity/Non Profit |
| PI Contribution | Provide technical support to help design a programme to monitor the efficacy and effectiveness of the introduction of a new type of bednet in Burkina Faso, Rwanda and Mozambique. |
| Collaborator Contribution | Liaison with National Malaria Control Programmes and local partners to set up data collection and regulatory approval. |
| Impact | Entomological and epidemiological data on the effectiveness of the Interceptor G2 bednet. Data on the ability of near infra-red spectroscopy for monitoring the age of mosquito populations. Update 2020 - Work conducted as part of this project has facilitated funding which will distribute 38 million improved bednets in Africa. Mathematical models predict that this will avert an additional 49.1 million clinical cases of malaria (95% confidence intervals 39.1-55.7 million cases) over the three-year life-expectancy of the net. This will save approximately 73,500 lives during this time. |
| Start Year | 2018 |
| Description | PB-PG-0317-20039 - Uptake, effectiveness and acceptability of routine screening of pregnant migrants for latent tuberculosis infection in antenatal care: a feasibility study |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Economic analysis |
| Collaborator Contribution | Collecting data |
| Impact | None yet |
| Start Year | 2019 |
| Description | Policy response to ECHO trial |
| Organisation | University of California, Berkeley |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Mathematical modelling |
| Collaborator Contribution | Expertise in reproductive health and modelling |
| Impact | Publication in The Lancet |
| Start Year | 2019 |
| Description | Polio Environmental Surveillance in Dhaka |
| Organisation | University of Virginia (UVa) |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Statistical and mathematical analysis; genetic sequencing of detected enteroviruses |
| Collaborator Contribution | Collection of demographic data, sewage physicochemical properties and pathogen data from sewage |
| Impact | None yet |
| Start Year | 2018 |
| Description | Population Dynamics of Human Ascariasis |
| Organisation | University of Westminster |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Data analysis, statistical and mathematical modelling through MRc-funded PhD student |
| Collaborator Contribution | Sharing of data on chemo-expulsion studies of Ascaris lumbricoides in Bangladesh for the analysis and modelling of the population dynamics of ascariasis in human populations |
| Impact | Publications, PubMed ID Number: 19208229; 20385140; 20620142 |
| Start Year | 2006 |
| Description | Population genomic statistical methods |
| Organisation | University of Oslo |
| Department | Department of Oceanography |
| Country | Norway |
| Sector | Academic/University |
| PI Contribution | Provided data analysis |
| Collaborator Contribution | They provided software and statistical methods |
| Impact | Software and publications |
| Start Year | 2015 |
| Description | Predicting the impact of transmission blocking vaccines for malaria |
| Organisation | National Institutes of Health (NIH) |
| Country | United States |
| Sector | Public |
| PI Contribution | Provided expertise in data analysis and mathematical modelling |
| Collaborator Contribution | Provided data from randomised control trial of new vaccine in Burkina Faso |
| Impact | No outputs yet |
| Start Year | 2019 |
| Description | Preparation of a business case for investment in the development of macrofilaricides for onchocerciasis |
| Organisation | MM Global Health Consulting |
| Country | Switzerland |
| Sector | Charity/Non Profit |
| PI Contribution | Modelling the epidemiological impact of hypothetical macrofilaricides in comparison with moxidectin and ivermectin across APOC projects in Africa. |
| Collaborator Contribution | Provision of framework to support business case Regular input Act as liaison with WHO and Bill and Melinda Gates Foundation. |
| Impact | No outputs known yet. Simulations will be linked to economic evaluations at Imperial College London. |
| Start Year | 2019 |
| Description | Prevention and Restriction on Anti Microbial Resistance AMR) in Pneumococci by Multi Level Modelling |
| Organisation | The Wellcome Trust Sanger Institute |
| Department | MRC Centre for Genomics and Global Health, WTCHG and WTSI |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Data analysis and lab work |
| Collaborator Contribution | Data provision |
| Impact | Multiple publications; sequenced data has emerged.Work ongoing on publication. |
| Start Year | 2012 |
| Description | Priority setting for healthcare services in India |
| Organisation | Center for Global Development |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Provision of technical expertise Analysis of data Policy translation (evidence into action) |
| Collaborator Contribution | CHAI - analysis of data NHAI - Policy makers - provision of data and identification of areas of development |
| Impact | No recognised ouputs yet |
| Start Year | 2020 |
| Description | Priority setting for healthcare services in India |
| Organisation | Clinton Health Access Initiative |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Provision of technical expertise Analysis of data Policy translation (evidence into action) |
| Collaborator Contribution | CHAI - analysis of data NHAI - Policy makers - provision of data and identification of areas of development |
| Impact | No recognised ouputs yet |
| Start Year | 2020 |
| Description | Priority setting for healthcare services in India |
| Organisation | Government of India |
| Department | National Health Authority, India |
| Country | India |
| Sector | Public |
| PI Contribution | Provision of technical expertise Analysis of data Policy translation (evidence into action) |
| Collaborator Contribution | CHAI - analysis of data NHAI - Policy makers - provision of data and identification of areas of development |
| Impact | No recognised ouputs yet |
| Start Year | 2020 |
| Description | Real time outbreak modelling and analysis |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | Continuous provision on modelling expertise and analysis for ongoing Ebola virus disease outbreak in DRC and current Corona virus outbreak. |
| Collaborator Contribution | Provision of data for analysis and coordination of interactions with additional modelling groups. |
| Impact | 40 reports sent to WHO which have been used to inform situational awareness and fed into policy decisions, particularly estimates of admissibility and future projections of case numbers for Ebola outbreak. |
| Start Year | 2010 |
| Description | Recent HIV infection surveillance to monitor HIV incidence and evaluate intervention impact |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Country | United States |
| Sector | Public |
| PI Contribution | - Development of mathematical and statistical models for analysing novel recent HIV infection surveillance data. - Design of evaluation study about impact of secondary schools on HIV risk and pregnancy amongst adolescent girls and young women. |
| Collaborator Contribution | - Collection and interpretation of novel surveillance data. |
| Impact | Not yet recognised |
| Start Year | 2018 |
| Description | Recent HIV infection surveillance to monitor HIV incidence and evaluate intervention impact |
| Organisation | Ministry of Health Malawi |
| Country | Malawi |
| Sector | Public |
| PI Contribution | - Development of mathematical and statistical models for analysing novel recent HIV infection surveillance data. - Design of evaluation study about impact of secondary schools on HIV risk and pregnancy amongst adolescent girls and young women. |
| Collaborator Contribution | - Collection and interpretation of novel surveillance data. |
| Impact | Not yet recognised |
| Start Year | 2018 |
| Description | Recent HIV infection surveillance to monitor HIV incidence and evaluate intervention impact |
| Organisation | University of California, San Francisco |
| Department | School of Medicine (UCSF) |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | - Development of mathematical and statistical models for analysing novel recent HIV infection surveillance data. - Design of evaluation study about impact of secondary schools on HIV risk and pregnancy amongst adolescent girls and young women. |
| Collaborator Contribution | - Collection and interpretation of novel surveillance data. |
| Impact | Not yet recognised |
| Start Year | 2018 |
| Description | Reciprocal capacity building workshop - focus on yellow fever outbreak and response |
| Organisation | Government of Brazil |
| Department | Ministry of Health Brazil |
| Country | Brazil |
| Sector | Public |
| PI Contribution | Provision of expertise in capacity building for modelling and data analytics - particularly for regional partners in LMICs. |
| Collaborator Contribution | MoH - provision of data for analysis Fiocruz - provision of field training for workshop for Imperial staff and coordination of networking |
| Impact | Workshop planned for July 2020. |
| Start Year | 2017 |
| Description | Reciprocal capacity building workshop - focus on yellow fever outbreak and response |
| Organisation | Oswaldo Cruz Foundation (Fiocruz) |
| Country | Brazil |
| Sector | Public |
| PI Contribution | Provision of expertise in capacity building for modelling and data analytics - particularly for regional partners in LMICs. |
| Collaborator Contribution | MoH - provision of data for analysis Fiocruz - provision of field training for workshop for Imperial staff and coordination of networking |
| Impact | Workshop planned for July 2020. |
| Start Year | 2017 |
| Description | Reconstructing dengue transmission intensity in Indonesia from multiple dtata sources |
| Organisation | Sanofi |
| Country | Global |
| Sector | Private |
| PI Contribution | Provision of Mathematical modelling expertise |
| Collaborator Contribution | Provision of data Expertise in data interpretation |
| Impact | Publication in PLoS NTDs Poster and talk at ASTMH (American Society of Tropical Medicine and Hygiene) |
| Start Year | 2018 |
| Description | Reconstructing dengue transmission intensity in Indonesia from multiple dtata sources |
| Organisation | Universitas Indonesia |
| Country | Indonesia |
| Sector | Academic/University |
| PI Contribution | Provision of Mathematical modelling expertise |
| Collaborator Contribution | Provision of data Expertise in data interpretation |
| Impact | Publication in PLoS NTDs Poster and talk at ASTMH (American Society of Tropical Medicine and Hygiene) |
| Start Year | 2018 |
| Description | Research to Improve the Detection and Treatment of Latent Tuberculosis Infection (RID-TB) |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Economic analysis |
| Collaborator Contribution | Collecting data |
| Impact | None yet |
| Start Year | 2018 |
| Description | Respiratory infections sample collection |
| Organisation | Mahidol University |
| Country | Thailand |
| Sector | Academic/University |
| PI Contribution | Data analysis |
| Collaborator Contribution | Provide knowledge, data, samples and DNA |
| Impact | Publications; sequenced data |
| Start Year | 2012 |
| Description | Restriction modification analysis |
| Organisation | University of Leicester |
| Department | University of Leicester, Proteomics facility |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provided strains, DNA and data analysis |
| Collaborator Contribution | Provided techniques and new strains |
| Impact | Publication and sequenced data |
| Start Year | 2015 |
| Description | START-IPT study collaborator |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We have produced models of Intermittent Preventive Treatment for malaria in school children, to assist the design of a trial and give an estimate of likely effect. |
| Collaborator Contribution | Design and carrying out a cluster-randomized trial of Intermittent Preventive Treatment for malaria in school children in Uganda. |
| Impact | Informed trial design. The collaboration is multi disciplinary, including mathematical modellers, clinicians, epidemiologists. |
| Start Year | 2014 |
| Description | Sanofi data collaboration |
| Organisation | Sanofi |
| Country | Global |
| Sector | Private |
| PI Contribution | We have carried out secondary analysis of trial data, to estimate the post-treatment prophylactic effect of artesunate amodiaquine. |
| Collaborator Contribution | They contributed data. |
| Impact | Published in BMC Medicine 2020. |
| Start Year | 2014 |
| Description | Sarah Cleveland - Glasgow |
| Organisation | University of Glasgow |
| Country | United Kingdom |
| Sector | Academic/University |