A multi-country analysis of temperature-mortality associations from a climate change perspective
Lead Research Organisation:
London School of Hygiene & Tropical Medicine
Department Name: Epidemiology and Population Health
Abstract
Non-optimal outdoor temperature is a known risk factor for human health, with increased mortality risk associated with both high and low exposures. Several studies have attempted to quantify the related impact in a changing climate, considering the predicted increase in average temperature and extreme weather events. However, temperature-mortality associations show a substantial geographical and temporal heterogeneity that is still largely unexplained, and little is known about the factors determining vulnerability or resilience of populations to the effects of temperature. This information is critical to produce reliable impact projections under climate change, and to develop effective public health policies to attenuate the health burden. This project aims to address these research gaps by offering a systematic evaluation of the association and future impact of temperature on mortality across populations with markedly different characteristics. This project benefits from the availability of the largest data set ever collected for this purpose, including data from 384 locations within 13 countries between 1972 and 2012. Analyses will be based on flexible analytical methods recently developed for modelling complex temperature-health relationships. A first assessment will explore the role of climatological, demographic, socio-economic and infrastructural characteristics in modifying the mortality risk of temperature. This information will be used in second assessment to project the impact under composite scenarios accounting for potential changes in susceptibility due to secular trends and implementation of mitigation and adaptation strategies. This project will provide a comprehensive characterization of the health effects of temperature and the related climate change impact, and a platform to quantitatively evaluate the benefits of alternative public health policies and adaptation measures.
Technical Summary
Non-optimal outdoor temperature is a known risk factor for human health, with increased mortality risk associated with both high and low exposures. Several studies have attempted to quantify the related impact in a changing climate, considering the predicted increase in average temperature and extreme weather events. However, temperature-mortality associations show a substantial geographical and temporal heterogeneity that is still largely unexplained, and little is known about the factors determining vulnerability or resilience of populations to the effects of temperature. This information is critical to produce reliable impact projections under climate change, and to develop effective public health policies to attenuate the health burden. This project aims to address these research gaps by offering a systematic evaluation of the association and future impact of temperature on mortality across populations with markedly different characteristics. This project benefits from the availability of the largest data set ever collected for this purpose, including data from 384 locations within 13 countries between 1972 and 2012. Analyses will be based on flexible analytical methods recently developed for modelling complex temperature-health relationships. A first assessment will explore the role of climatological, demographic, socio-economic and infrastructural characteristics in modifying the mortality risk of temperature. This information will be used in second assessment to project the impact under composite scenarios accounting for potential changes in susceptibility due to secular trends and implementation of mitigation and adaptation strategies. This project will provide a comprehensive characterization of the health effects of temperature and the related climate change impact, and a platform to quantitatively evaluate the benefits of alternative public health policies and adaptation measures.
Planned Impact
The project will primarily benefit the community of researchers and public health practitioners working in academia, governmental health organisations or charities. The multi-country nature of the project, and the provision of projections of climate change impact at a small geographical scale including different scenarios of adaptation strategies, will ensure a large audience to the research findings, feeding a discussion about the possible public health responses. More generally, the results of this study will also benefit politicians, non-governmental organisations or members of associations involved in the discussion and decision-making. The question of climate change is a hotly debated topic, in which potential health consequences have to be considered within a broad assessment of economical, technical and societal issues. This study will offer scientific evidence on temperature-related health impact to inform such discussion.
Organisations
- London School of Hygiene & Tropical Medicine (Lead Research Organisation)
- National and Kapodistrian University of Athens (Collaboration)
- Sorbonne University (Collaboration)
- Columbia University (Collaboration)
- Queensland University of Technology (QUT) (Collaboration)
- Umea University (Collaboration)
- Nagasaki University (Collaboration)
- University of Ottawa (Collaboration)
- University of Hasselt (Collaboration)
- Public Health Agency of Canada (Collaboration)
- Spanish National Research Council (CSIC) (Collaboration)
- Ludwig Maximilian University of Munich (LMU Munich) (Collaboration)
- University of Valencia (Collaboration)
- Seoul National University (Collaboration)
- Fudan University (Collaboration)
- Universidade de São Paulo (Collaboration)
- HARVARD UNIVERSITY (Collaboration)
- National Taiwan University (Collaboration)
- University of Tsukuba (Collaboration)
- PUBLIC HEALTH ENGLAND (Collaboration)
- Center for Research in Environmental Epidemiology (Collaboration)
- Centers for Disease Control and Prevention (CDC) (Collaboration)
- Lazio Regional Health Service (Collaboration)
- London School of Hygiene and Tropical Medicine (LSHTM) (Collaboration)
- University of Queensland (Collaboration)
- Children's Hospital of Philadelphia (Collaboration)
- University of Leuven (Collaboration)
Publications
Chung Y
(2018)
Changing Susceptibility to Non-Optimum Temperatures in Japan, 1972-2012: The Role of Climate, Demographic, and Socioeconomic Factors.
in Environmental health perspectives
De' Donato FK
(2015)
Changes in the Effect of Heat on Mortality in the Last 20 Years in Nine European Cities. Results from the PHASE Project.
in International journal of environmental research and public health
Gasparrini A
(2016)
Changes in Susceptibility to Heat During the Summer: A Multicountry Analysis.
in American journal of epidemiology
Yang J
(2015)
Cardiovascular mortality risk attributable to ambient temperature in China.
in Heart (British Cardiac Society)
Tobías A
(2017)
Brief Report: Investigating Uncertainty in the Minimum Mortality Temperature: Methods and Application to 52 Spanish Cities.
in Epidemiology (Cambridge, Mass.)
Ahn JV
(2018)
Associations between objectively measured physical activity and later mental health outcomes in children: findings from the UK Millennium Cohort Study.
in Journal of epidemiology and community health
Sera F
(2019)
An extended mixed-effects framework for meta-analysis.
in Statistics in medicine
Cox B
(2016)
Ambient temperature as a trigger of preterm delivery in a temperate climate.
in Journal of epidemiology and community health
Liu C
(2019)
Ambient Particulate Air Pollution and Daily Mortality in 652 Cities.
in The New England journal of medicine
| Description | Modern methods for time series analysis |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Temperature, climate change and health |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Use of DLNMs in temperature-health studies |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| URL | http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/10kxh85C77hGm5PFkch6qfQ/ |
| Title | Personal website |
| Description | The website provides access to the outputs of my research, such as pdf versions and supplemental material of the published papers, summaries and updates of my research activity, and other information. In particular, scripts and data for reproducing the results of methodological or substantive papers are made available thorough the website. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2012 |
| Provided To Others? | Yes |
| Impact | The website is visited by 5-10 visitors each day. They download materials such as articles, scripts and data. |
| URL | http://www.ag-myresearch.com/ |
| Title | R package dlnm |
| Description | The package contains functions and data examples for running distributed lag non-linear models. It is provided within the free software R and downloadable from internet through the R program. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2009 |
| Provided To Others? | Yes |
| Impact | The software implementation in a free program has boosted the use of DLNMs among researchers in different countries, primarily (but not only) for studies on temperature and air pollution. Also, the package, developed in parallel with the statistical framework, offer a vehicle to promote the methodology and its use among non-statisticians. |
| URL | http://cran.r-project.org/web/packages/dlnm/index.html |
| Title | R package mvmeta |
| Description | The package contains functions and data examples for running univariate or multivariate meta-analysis and meta-regression. It is provided within the free software R and downloadable from internet through the R program. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2011 |
| Provided To Others? | Yes |
| Impact | The software implementation in a free program facilitates the use of multivariate meta-analytical techniques in the research community. Also, the package, developed in parallel with the statistical framework, offer a vehicle to promote the methodology and its use among non-statisticians. |
| URL | http://cran.r-project.org/web/packages/mvmeta/index.html |
| Title | Distributed lag non-linear models |
| Description | Flexible modelling technique for describing the temporal pattern of linear or non-linear exposure-response associations, termed exposure-lag-response associations. |
| Type Of Material | Data analysis technique |
| Year Produced | 2009 |
| Provided To Others? | Yes |
| Impact | Huge impact on research on the health effects of temperature and other risk factors, certified by the use of the technique in several peer-reviewed articles by different research groups: http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/10kxh85C77hGm5PFkch6qfQ/ |
| Title | Multivariate meta-analysis |
| Description | Application of multivariate-meta-analysis to pool complex associations defined by multiple parameters |
| Type Of Material | Data analysis technique |
| Year Produced | 2012 |
| Provided To Others? | Yes |
| Impact | Impact on applications of meta-analysis approaches, certified by the use of the technique in several peer-reviewed articles by different research groups: http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1bE6r3sM055G4oxSb_eqi8o/ |
| Title | Personal website |
| Description | The website provides access to the outputs of my research, such as pdf versions and supplemental material of the published papers, summaries and updates of my research activity, and other information. In particular, scripts and data for reproducing the results of methodological or substantive papers are made available thorough the website. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2012 |
| Provided To Others? | Yes |
| Impact | The website is visited by 5-10 visitors each day. They download materials such as articles, scripts and data. |
| URL | http://www.ag-myresearch.com/ |
| Title | R package dlnm |
| Description | The package contains functions and data examples for running distributed lag non-linear models. It is provided within the free software R and downloadable from internet through the R program. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2009 |
| Provided To Others? | Yes |
| Impact | The software implementation in a free program has boosted the use of DLNMs among researchers in different countries, primarily (but not only) for studies on temperature and air pollution. Also, the package, developed in parallel with the statistical framework, offer a vehicle to promote the methodology and its use among non-statisticians. Huge impact on research on the health effects of temperature and other risk factors, certified by the use of the technique in several peer-reviewed articles by different research groups: http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1bE6r3sM055G4oxSb_eqi8o/ |
| URL | http://cran.r-project.org/web/packages/dlnm/index.html |
| Title | R package mvmeta |
| Description | The package contains functions and data examples for running univariate or multivariate meta-analysis and meta-regression. It is provided within the free software R and downloadable from internet through the R program. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2011 |
| Provided To Others? | Yes |
| Impact | The software implementation in a free program facilitates the use of multivariate meta-analytical techniques in the research community. Also, the package, developed in parallel with the statistical framework, offer a vehicle to promote the methodology and its use among non-statisticians. Impact on application of meta-analytical approaches, certified by the use of the technique in several peer-reviewed articles by different research groups: http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/10kxh85C77hGm5PFkch6qfQ/ |
| URL | http://cran.r-project.org/web/packages/mvmeta/index.html |
| Description | Developing Methods to Enhance Environmental Epidemiological Risk Assessments |
| Organisation | Centers for Disease Control and Prevention (CDC) |
| Department | Division of Parasitic Diseases and Malaria |
| Country | United States |
| Sector | Public |
| PI Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Collaborator Contribution | Leading the development of the research project, leading on writing up of peer-review publications |
| Impact | Not yet |
| Start Year | 2014 |
| Description | Methodological work on distributed lag linear and non-linear models |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Leading the development of the methodological research, leading on writing up of peer-review publications |
| Collaborator Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Impact | Peer-reviewed publications in international journals and oral presentations in international congresses |
| Start Year | 2014 |
| Description | Methodological work on distributed lag linear and non-linear models |
| Organisation | Ludwig Maximilian University of Munich (LMU Munich) |
| Department | Department of Neurology |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Leading the development of the methodological research, leading on writing up of peer-review publications |
| Collaborator Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Impact | Peer-reviewed publications in international journals and oral presentations in international congresses |
| Start Year | 2014 |
| Description | Modelling health effects of environmental exposures |
| Organisation | Children's Hospital of Philadelphia |
| Department | Center for Pediatric Clinical Effectiveness |
| Country | United States |
| Sector | Hospitals |
| PI Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Collaborator Contribution | Leading the development of the methodological research, leading on writing up of peer-review publications |
| Impact | Peer-reviewed publications in international journals and oral presentations in international congresses |
| Start Year | 2012 |
| Description | Modelling health effects of environmental exposures |
| Organisation | Columbia University |
| Department | Department of Environmental Health Sciences |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Collaborator Contribution | Leading the development of the methodological research, leading on writing up of peer-review publications |
| Impact | Peer-reviewed publications in international journals and oral presentations in international congresses |
| Start Year | 2012 |
| Description | Modelling health effects of environmental exposures |
| Organisation | Harvard University |
| Department | Harvard T.H. Chan School of Public Health |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Collaborator Contribution | Leading the development of the methodological research, leading on writing up of peer-review publications |
| Impact | Peer-reviewed publications in international journals and oral presentations in international congresses |
| Start Year | 2012 |
| Description | Modelling health effects of environmental exposures |
| Organisation | Public Health Agency of Canada |
| Department | Canada Prenatal Nutrition Program |
| Country | Canada |
| Sector | Public |
| PI Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Collaborator Contribution | Leading the development of the methodological research, leading on writing up of peer-review publications |
| Impact | Peer-reviewed publications in international journals and oral presentations in international congresses |
| Start Year | 2012 |
| Description | Modelling health effects of environmental exposures |
| Organisation | University of Hasselt |
| Department | Centre for Environmental Sciences |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Collaborator Contribution | Leading the development of the methodological research, leading on writing up of peer-review publications |
| Impact | Peer-reviewed publications in international journals and oral presentations in international congresses |
| Start Year | 2012 |
| Description | Modelling health effects of environmental exposures |
| Organisation | University of Leuven |
| Department | Department of Public Health and Primary Care |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Collaborator Contribution | Leading the development of the methodological research, leading on writing up of peer-review publications |
| Impact | Peer-reviewed publications in international journals and oral presentations in international congresses |
| Start Year | 2012 |
| Description | Modelling health effects of environmental exposures |
| Organisation | University of Ottawa |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Technical contribution on statistical methods and software programs, intellectual contribution to publications |
| Collaborator Contribution | Leading the development of the methodological research, leading on writing up of peer-review publications |
| Impact | Peer-reviewed publications in international journals and oral presentations in international congresses |
| Start Year | 2012 |
| Description | Multi-Country Multi-City (MCC) Collaborative Research Network |
| Organisation | Harvard University |
| Department | Harvard T.H. Chan School of Public Health |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | I have established and currently coordinating an international collaboration of more than 80 researchers from more than 40 countries, working on a program aiming to produce epidemiological evidence on associations between environmental stressors, climate, and health (http://mccstudy.lshtm.ac.uk/). The list of partners is long: see http://mccstudy.lshtm.ac.uk/participants/. |
| Collaborator Contribution | It is collaborative network that has produced already important research outputs (http://mccstudy.lshtm.ac.uk/publications/). |
| Impact | http://mccstudy.lshtm.ac.uk/publications/ |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Fudan University |
| Country | China |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Harvard University |
| Department | Harvard T.H. Chan School of Public Health |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Lazio Regional Health Service |
| Country | Italy |
| Sector | Public |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Nagasaki University |
| Country | Japan |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | National Taiwan University |
| Country | Taiwan, Province of China |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Public Health England |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Queensland University of Technology (QUT) |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Seoul National University |
| Country | Korea, Republic of |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Spanish National Research Council (CSIC) |
| Country | Spain |
| Sector | Public |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Umea University |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | Universidade de São Paulo |
| Country | Brazil |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | University of Ottawa |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | University of Queensland |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | Multi-country analysis of temperature effects |
| Organisation | University of Tsukuba |
| Country | Japan |
| Sector | Academic/University |
| PI Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | Peer-reviewed publications, oral contributions and workshops in international congresses |
| Start Year | 2013 |
| Description | PHASE project |
| Organisation | Center for Research in Environmental Epidemiology |
| Country | Spain |
| Sector | Academic/University |
| PI Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | One peer-reviewed article: de' Donato FK, Leone M, Scortichini M, De Sario M, Katsouyanni K, Lanki T, Basagana X, Ballester F, Astrom C, Paldy A, Pascal M, Gasparrini A, Menne B, Michelozzi M. Changes in the effect of heat on mortality in the last 20 years in nine European cities. Results from the PHASE project. International Journal of Environmental Research and Public Health. 2015;12(12):15567-15583. Oral contributions in international conferences: Scortichini M, de'Donato F, Astrom DO, Basagana X, Gasparrini A, Iniguez C, Katsouyanni K, Lanki T, Paldy A, Pascal M, Michelozzi P, Analitis A. An annual comparison of the effects of summer temperatures on mortality for 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. de'Donato F, Leone M, Analitis A, Paldy A, Lanki T, Gasparrini A, Pascal M, Astrom C, Ballester F, Basagana X, Michelozzi P. Temporal variations in the effect heat and cold, by age group and cause of death in 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. |
| Start Year | 2012 |
| Description | PHASE project |
| Organisation | Lazio Regional Health Service |
| Country | Italy |
| Sector | Public |
| PI Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | One peer-reviewed article: de' Donato FK, Leone M, Scortichini M, De Sario M, Katsouyanni K, Lanki T, Basagana X, Ballester F, Astrom C, Paldy A, Pascal M, Gasparrini A, Menne B, Michelozzi M. Changes in the effect of heat on mortality in the last 20 years in nine European cities. Results from the PHASE project. International Journal of Environmental Research and Public Health. 2015;12(12):15567-15583. Oral contributions in international conferences: Scortichini M, de'Donato F, Astrom DO, Basagana X, Gasparrini A, Iniguez C, Katsouyanni K, Lanki T, Paldy A, Pascal M, Michelozzi P, Analitis A. An annual comparison of the effects of summer temperatures on mortality for 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. de'Donato F, Leone M, Analitis A, Paldy A, Lanki T, Gasparrini A, Pascal M, Astrom C, Ballester F, Basagana X, Michelozzi P. Temporal variations in the effect heat and cold, by age group and cause of death in 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. |
| Start Year | 2012 |
| Description | PHASE project |
| Organisation | National and Kapodistrian University of Athens |
| Country | Greece |
| Sector | Academic/University |
| PI Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | One peer-reviewed article: de' Donato FK, Leone M, Scortichini M, De Sario M, Katsouyanni K, Lanki T, Basagana X, Ballester F, Astrom C, Paldy A, Pascal M, Gasparrini A, Menne B, Michelozzi M. Changes in the effect of heat on mortality in the last 20 years in nine European cities. Results from the PHASE project. International Journal of Environmental Research and Public Health. 2015;12(12):15567-15583. Oral contributions in international conferences: Scortichini M, de'Donato F, Astrom DO, Basagana X, Gasparrini A, Iniguez C, Katsouyanni K, Lanki T, Paldy A, Pascal M, Michelozzi P, Analitis A. An annual comparison of the effects of summer temperatures on mortality for 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. de'Donato F, Leone M, Analitis A, Paldy A, Lanki T, Gasparrini A, Pascal M, Astrom C, Ballester F, Basagana X, Michelozzi P. Temporal variations in the effect heat and cold, by age group and cause of death in 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. |
| Start Year | 2012 |
| Description | PHASE project |
| Organisation | Sorbonne University |
| Country | France |
| Sector | Academic/University |
| PI Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | One peer-reviewed article: de' Donato FK, Leone M, Scortichini M, De Sario M, Katsouyanni K, Lanki T, Basagana X, Ballester F, Astrom C, Paldy A, Pascal M, Gasparrini A, Menne B, Michelozzi M. Changes in the effect of heat on mortality in the last 20 years in nine European cities. Results from the PHASE project. International Journal of Environmental Research and Public Health. 2015;12(12):15567-15583. Oral contributions in international conferences: Scortichini M, de'Donato F, Astrom DO, Basagana X, Gasparrini A, Iniguez C, Katsouyanni K, Lanki T, Paldy A, Pascal M, Michelozzi P, Analitis A. An annual comparison of the effects of summer temperatures on mortality for 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. de'Donato F, Leone M, Analitis A, Paldy A, Lanki T, Gasparrini A, Pascal M, Astrom C, Ballester F, Basagana X, Michelozzi P. Temporal variations in the effect heat and cold, by age group and cause of death in 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. |
| Start Year | 2012 |
| Description | PHASE project |
| Organisation | Umea University |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | One peer-reviewed article: de' Donato FK, Leone M, Scortichini M, De Sario M, Katsouyanni K, Lanki T, Basagana X, Ballester F, Astrom C, Paldy A, Pascal M, Gasparrini A, Menne B, Michelozzi M. Changes in the effect of heat on mortality in the last 20 years in nine European cities. Results from the PHASE project. International Journal of Environmental Research and Public Health. 2015;12(12):15567-15583. Oral contributions in international conferences: Scortichini M, de'Donato F, Astrom DO, Basagana X, Gasparrini A, Iniguez C, Katsouyanni K, Lanki T, Paldy A, Pascal M, Michelozzi P, Analitis A. An annual comparison of the effects of summer temperatures on mortality for 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. de'Donato F, Leone M, Analitis A, Paldy A, Lanki T, Gasparrini A, Pascal M, Astrom C, Ballester F, Basagana X, Michelozzi P. Temporal variations in the effect heat and cold, by age group and cause of death in 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. |
| Start Year | 2012 |
| Description | PHASE project |
| Organisation | University of Valencia |
| Country | Spain |
| Sector | Academic/University |
| PI Contribution | Contributed to the definition of the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Collaborator Contribution | Leading the collaborative project; formalized the collaboration; defined the collaboration format, the research directions and research outcomes; leading or contribution on specific sub-projects |
| Impact | One peer-reviewed article: de' Donato FK, Leone M, Scortichini M, De Sario M, Katsouyanni K, Lanki T, Basagana X, Ballester F, Astrom C, Paldy A, Pascal M, Gasparrini A, Menne B, Michelozzi M. Changes in the effect of heat on mortality in the last 20 years in nine European cities. Results from the PHASE project. International Journal of Environmental Research and Public Health. 2015;12(12):15567-15583. Oral contributions in international conferences: Scortichini M, de'Donato F, Astrom DO, Basagana X, Gasparrini A, Iniguez C, Katsouyanni K, Lanki T, Paldy A, Pascal M, Michelozzi P, Analitis A. An annual comparison of the effects of summer temperatures on mortality for 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. de'Donato F, Leone M, Analitis A, Paldy A, Lanki T, Gasparrini A, Pascal M, Astrom C, Ballester F, Basagana X, Michelozzi P. Temporal variations in the effect heat and cold, by age group and cause of death in 9 European cities. International Society for Environmental Epidemiology (ISEE) Conference - Seattle, 24-28 August 2014. |
| Start Year | 2012 |
| Title | R package dlnm |
| Description | The package contains functions and data examples for running distributed lag non-linear models. The software is freely downloadable by everybody, and it is licensed under the GNU General Public License, meaning that, under appropriate reference and the assurance that novel material is provided under the same licence terms, it can be modified and extended by other researchers. |
| IP Reference | |
| Protection | Copyrighted (e.g. software) |
| Year Protection Granted | 2009 |
| Licensed | Yes |
| Impact | The software implementation in a free program has boosted the use of DLNMs among researchers in different countries, primarily (but not only) for studies on temperature and air pollution. Also, the package, developed in parallel with the statistical framework, offer a vehicle to promote the methodology and its use among non-statisticians. |
| Title | R package mvmeta |
| Description | The package contains functions and data examples for running univariate or multivariate meta-analysis and meta-regression. The software is freely downloadable by everybody, and it is licensed under the GNU General Public License, meaning that, under appropriate reference and the assurance that novel material is provided under the same licence terms, it can be modified and extended by other researchers. |
| IP Reference | |
| Protection | Copyrighted (e.g. software) |
| Year Protection Granted | 2011 |
| Licensed | Yes |
| Impact | The software implementation in a free program facilitates the use of multivariate meta-analytical techniques in the research community. Also, the package, developed in parallel with the statistical framework, offer a vehicle to promote the methodology and its use among non-statisticians. |
| Title | R package dlnm |
| Description | The package contains functions and data examples for running distributed lag non-linear models. It is provided within the free software R and downloadable from internet through the R program. |
| Type Of Technology | Software |
| Year Produced | 2009 |
| Open Source License? | Yes |
| Impact | The software implementation in a free program has boosted the use of DLNMs among researchers in different countries, primarily (but not only) for studies on temperature and air pollution. Also, the package, developed in parallel with the statistical framework, offer a vehicle to promote the methodology and its use among non-statisticians. |
| URL | http://cran.r-project.org/web/packages/dlnm/index.html |
| Title | R package mvmeta |
| Description | The package contains functions and data examples for running univariate or multivariate meta-analysis and meta-regression. It is provided within the free software R and downloadable from internet through the R program. |
| Type Of Technology | Software |
| Year Produced | 2011 |
| Open Source License? | Yes |
| Impact | The software implementation in a free program facilitates the use of multivariate meta-analytical techniques in the research community. Also, the package, developed in parallel with the statistical framework, offer a vehicle to promote the methodology and its use among non-statisticians. |
| URL | http://cran.r-project.org/web/packages/mvmeta/index.html |
| Description | Centre for Statistical Modelling (CSM) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | Yes |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Centre of the London School of Hygiene & Tropical Medicine Seminars and other activities are usually attended by 50-100 researchers, PhD or MSc students |
| Year(s) Of Engagement Activity | 2011,2012,2013,2014,2015,2016,2017,2018,2019,2020 |
| URL | http://csm.lshtm.ac.uk/ |
| Description | Invited talks |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Series of invited talks and workshops in well-known research institutions and companies, such as Harvard School of Public Health, Karolinska Institute, Royal Statistical Society, The Children Hospital of Philadelphia, Centre for Research in Environmental Epidemiology (CREAL), University of Pennsylvania, Ludwig Maximilians University, Swiss Tropical and Public Health Institute, Open University, St George's University of London, IQVIA, European Centre for Medium-Range Weather Forecasts (ECMWF), Centers for Disease Control and Prevention (CDC), Emory University |
| Year(s) Of Engagement Activity | 2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020 |