Immunity to multiple pathogens: identification of a fungal immune receptor in barley to ascomycete and basidiomycete fungi

Lead Research Organisation: University of East Anglia
Department Name: Sainsbury Laboratory


The majority of plants are resistant to the majority of pathogens that exist in nature. In contrast, it is the minority of interactions that permit lifecycle completion of the pathogen. The proclivity of nonhost resistance to the majority of pathogens suggests plants have a substantial capacity to resist various pathogens and/or that pathogens must make crucial adaptations to proliferate on a plant species. We have identified a resistance locus that conditions resistance to the ascomycete and basidiomycete fungi Magnaporthe oryzae and Puccinia striiformis f. sp. tritici. These two pathogens cause significant impact on global wheat and rice production, and the possibility that the same immune receptor conditions multiple pathogen recognition has profound implications in plant pathology. The project will involve the isolation of the fungal immune receptor through a combination of map-based cloning, association genetics, and bioinformatics.


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Studentship Projects

Project Reference Relationship Related To Start End Student Name
BB/M011216/1 01/10/2015 30/09/2023
1786354 Studentship BB/M011216/1 01/10/2016 30/09/2020 Samuel Holden
Description Silvio 
Organisation University of Bologna
Country Italy 
Sector Academic/University 
PI Contribution Technical training and expertise, helping our partners to clone their genes of interest
Collaborator Contribution Access to a TILLING population of barley, which we are using to identify our own genes of interest
Impact None yet
Start Year 2017