This student is joining the MIBTP training year and will select a PhD project in Oct 2018

Lead Research Organisation: University of Birmingham
Department Name: Sch of Biosciences


This student is joining the MIBTP training year and will select a PhD project in Oct 2018


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Studentship Projects

Project Reference Relationship Related To Start End Student Name
BB/M01116X/1 01/10/2015 30/09/2023
1898467 Studentship BB/M01116X/1 02/10/2017 30/09/2021 Joanna Chustecki
Description -During time spent on this research, I have developed a novel analysis pipeline taking video data of mitochondrial motion captured on the confocal microscope and analyses it using various video tracking softwares, constructing social networks of the interactions between mitochondria, not before done in plants. We have illuminated the heterogeneity in social network statistics across the mitochondrial population in single cells.
-We have developed a novel model of mitochondrial motion in plant cells.
-We have used this model to discover where in potential morphospace these social networks of plant mitochondria lie, and how mitochondrial motion in plant cells has evolved to give the most efficient movement to balance individual energy conservation and delivery of information around the cell.
-We have generated new plant lines by crossing mitochondrial fluorescence into the msh1 mismatch repair mutant. This will give us insight into the motion of mitochondria in genetically perturbed plants. This will complement work done so far on the physically perturbed friendly-mitoGFP mutant.
Exploitation Route The aim of this research is to understand the energy efficiency of mitochondrial motion in wild type and mutant cells. IT therefore has implications for those working in agriculture and plant biotechnology sectors, looking at food security. Understanding how changes to the physical colocalisation and motion of organelles within plant cells carries potential of the increased energy delivery throughout plant cells. Arabidopsis thalaina being the system we used is an ideal model for transferring what we uncover into crop plants.
On an academic level, this methodology we have implemented may open up new avenues for researchers studying other organisms to undertake network analysis of physical and temporal interactions.
Sectors Agriculture, Food and Drink,Manufacturing, including Industrial Biotechology

Description Maddox prize attendance blog 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact I attended the John Maddox Prize award ceremony at the Wellcome collection, hosted by Sense about Science. I was encouraged to write a blog piece about this, and as I has done an internship with Sense about Science supported by BBSRC and the MIBTP scheme, it was uploaded to the MIBTP blog so new PhD students or those already in the program can see what opportunities are available to them.
Year(s) Of Engagement Activity 2020
Description Mathematics postgraduate seminar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Talk given to Mathematics department and the University of Birmingham for their postgraduate students. Sparked interesting chats and brought a biological application of modeling work to the department.
Year(s) Of Engagement Activity 2020