Modelling biofilms in heterogeneous environments

Lead Research Organisation: University of Edinburgh
Department Name: Sch of Physics and Astronomy

Abstract

When biofilms aggregate on a surface, they form a structure known as a biofilm. This structure affords the bacterial colony higher resistances to both chemical and physical removal methods than their planktonic counterparts. Understanding how biofilms grow, proliferate and endure is an important area of research in both clinical and industrial perspectives.

Much of the research into bacterial populations takes place in very idealised conditions consisting of monospecies populations, spatially uniform drug concentrations and so on. Using various computational modelling techniques, this project aims to investigate the effects of environments which are more varying in their nature, including spatially heterogeneous drug concentrations, multispecies biofilms and non-uniform surfaces exposed to an external flow field.

Publications

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Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/R512242/1 01/10/2017 30/09/2021
1942225 Studentship EP/R512242/1 01/09/2017 31/08/2021 Patrick Charles Sinclair