Engineering genetic regulation in Clostridium to improve industrial properties
Lead Research Organisation:
Imperial College London
Department Name: Life Sciences
Abstract
Many commercially valuable chemicals are produced from unsustainable and environmentally damaging petrochemical sources. For these reasons, routes of chemical production that are carbon-neutral and are sourced from renewable starting materials are desirable. Clostridium are anaerobic bacteria with members innately able to produce a variety of commercially valuable chemicals from plant-based matter via the acetone-butanol-ethanol (ABE) fermentation pathway. This process has been commercialised by Green Biologics Ltd. who have developed a highly productive industrial fermentation platform. However, a number of Clostridium's characteristics limit their fermentation potential under industrial conditions. The aim of this project is to use a novel strain engineering technique to generate strains of Clostridium with enhanced properties relevant to Green Biologics Ltd. industrial process.
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
BB/R505791/1 | 01/10/2017 | 31/12/2021 | |||
1960943 | Studentship | BB/R505791/1 | 30/09/2017 | 22/12/2021 |