Development of new antimicrobial surfaces- for oral health care and wound dressings

Lead Research Organisation: University College London
Department Name: Chemistry

Abstract

The project will involve the synthesis and characterisation of a new class of wound healing agent using light. We will seek to understand the mechanism of how light kills microbes on nanoparticle incorporated polymers. We will understand the physical chemistry of how nanoparticles absorb light and transfer this into radicals or singlet oxygen. This will be achieved by measuring fluorescence, electron paramagnetic resonance and chemical assays. This understanding will enable us to make more effective medical grade polymers with light activated agents and surfactants (by optimising the amounts needed and location within the polymer) to enhance wound healing and help reduce for example the occurrence of bed sores. The project will also look at the residues of trace chemicals on polymer materials and the ways that surfaces can be transformed to inhibit biofilms formation by changing the surface microstructure and chemical composition

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/S515255/1 01/10/2018 30/09/2022
2089246 Studentship EP/S515255/1 24/09/2018 30/09/2022 Georgia Sian Fleet