Reverse engineering impingement in total hip replacements

Lead Research Organisation: University of Leeds
Department Name: Mechanical Engineering

Abstract

Hip replacement surgery is being performed on increasing numbers of patients, additionally greater demands are being placed on prostheses due to obesity and increasing patient expectations. As a consequence the number of revision surgeries which have higher associated costs and poorer outcomes are escalating. A significant proportion of failures are the result of mechanical mechanisms, often caused by impingement (between hip replacement components and/or bony structures). The key factors affecting the incidence and consequences of impingement are implant design, patient and surgical variation.
Better understanding of the factors that lead to revision is very important, the frequency of THR and revision THR procedures are expected to more than double by 2030 [Kurtz,JBJSAm,2007]. Revision surgery costs significantly more than primary surgery [Vanhegan, JBJSBr, 2012] and ultimately has poorer outcomes for patients. Recent National Joint Registry data cites the leading causes of mechanical failure as being dislocation, subluxation and aseptic loosening. The latter is caused by high torques, as well as biological responses to excessive wear. A root cause of all of these failure modes can be impingement, and therefore reducing the occurrence and severity of impingement following THR will reduce associated failures and improve outcomes.
The effects of patient hip bony anatomy and component positioning on the likelihood and occurrence of impingement are not known. This studentship will develop methodologies to investigate these parameters in patient specific models in an experimental anatomical simulator.

Publications

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Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/R512291/1 01/10/2017 30/06/2022
2091202 Studentship EP/R512291/1 01/10/2017 30/09/2021 Simon Paul Williams
 
Description Industrial placement during second year CDT TERM 
Organisation DePuy Synthes
Country United States 
Sector Private 
PI Contribution Spent three weeks shadowing DePuy engineers in a laboratory environment. Conducted research into hip simulators to provide information for my PhD.
Collaborator Contribution DePuy engineers expertise, access to their Beeston, UK facility, office space, laboratory access.
Impact Gained insight into an industrial laboratory and provided context for my PhD research.
Start Year 2019
 
Description iMBE 'Engineer a human' 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact I took part in a public engagement event at Leeds City College which aimed at educating and inspiring college-aged students to pursue a career in medical and biological engineering.
Year(s) Of Engagement Activity 2018